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CTP and coordinate ParB partition complex dynamics and ParA-ATPase activation for ParABS-mediated DNA partitioning

Authors: James A Taylor, Yeonee Seol, Jagat Budhathoki, Keir C Neuman, Kiyoshi Mizuuchi

Journal: Elife

PubMed ID: 34286695

Doi: 10.7554/eLife.65651

Products & Services: PCR Cloning and Subcloning

The circadian clock gates adult emergence by controlling the timecourse of metamorphosis

Authors: Brandon Mark, Liliana Bustos-González, Guadalupe Cascallares, Felipe Conejera, John Ewer

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34183412

Doi: 10.1073/pnas.2023249118

Products & Services: Proteins, Expression, Isolation and Analysis

Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes

Authors: Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P M Labib

Journal: Biochem J

PubMed ID: 34195792

Doi: 10.1042/BCJ20210315

Products & Services: Mammalian Expression

KDM1A Promotes Immunosuppression in Hepatocellular Carcinoma by Regulating PD-L1 through Demethylating MEF2D

Authors: Yonglan Wang, Kun Cao

Journal: J Immunol Res

PubMed ID: 34307695

Doi: 10.1155/2021/9965099

Structural and immunological characterization of an epitope within the PAN motif of ectodomain I in apical membrane antigen 1 for vaccine development

Authors: Amarin Rittipornlertrak, Boondarika Nambooppha, Anucha Muenthaisong, Veerasak Punyapornwithaya, Saruda Tiwananthagorn, Yang-Tsung Chung, Bumduuren Tuvshintulga, Thillaiampalam Sivakumar, Naoaki Yokoyama, Nattawooti Sthitmatee

Journal: PeerJ

PubMed ID: 34316404

Doi: 10.7717/peerj.11765

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Identification of Three Clf-Sdr Subfamily Proteins in , and Comparative Genomics Analysis of a Locus Encoding CWA Proteins in Species

Authors: Zhewei Sun, Xueya Zhang, Danying Zhou, Kexin Zhou, Qiaoling Li, Hailong Lin, Wei Lu, Hongmao Liu, Junwan Lu, Xi Lin, Kewei Li, Teng Xu, Mei Zhu, Qiyu Bao, Hailin Zhang

Journal: Front Microbiol

PubMed ID: 34394031

Doi: 10.3389/fmicb.2021.691087

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The enhanced phosphorus use efficiency in phosphate-deficient and mycorrhiza-inoculated barley seedlings involves activation of different sets of PHT1 transporters in roots

Authors: Rajat Srivastava, Parul Sirohi, Harsh Chauhan, Rahul Kumar

Journal: Planta

PubMed ID: 34312721

Doi: 10.1007/s00425-021-03687-0

Products & Services: Protein Tools

Global Profiling of Phosphorylation Reveals the Barley Roots Response to Phosphorus Starvation and Resupply

Authors: Zengke Ma, Juncheng Wang, Chengdao Li, Panrong Ren, Lirong Yao, Baochun Li, Yaxiong Meng, Xiaole Ma, Erjing Si, Ke Yang, Xunwu Shang, Huajun Wang

Journal: Front Plant Sci

PubMed ID: 34335649

Doi: 10.3389/fpls.2021.676432

Products & Services: Protein Tools

AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment

Authors: Yue Yu, Shu-Ming Ye, De-Yun Liu, Li-Qi Yang

Journal: Exp Anim

PubMed ID: 34305077

Doi: 10.1538/expanim.21-0056

Products & Services: Custom DNA/RNA Oligos

CABE-RY: A PAM-flexible dual-mutation base editor for reliable modeling of multi-nucleotide variants

Authors: Wanyu Tao, Qing Liu, Shisheng Huang, Xin Wang, Shiyuan Qu, Junfan Guo, Danfeng Ou, Guanglei Li, Yu Zhang, Xiangmin Xu, Xingxu Huang

Journal: Mol Ther Nucleic Acids

PubMed ID: 34513298

Doi: 10.1016/j.omtn.2021.07.016

Products & Services: PCR Cloning and Subcloning

Characterization of the Role of the Neoxanthin Synthase Gene in Carotenoid Biosynthesis in Chinese Kale

Authors: Yue Jian, Chenlu Zhang, Yating Wang, Zhiqing Li, Jing Chen, Wenting Zhou, Wenli Huang, Min Jiang, Hao Zheng, Mengyao Li, Huiying Miao, Fen Zhang, Huanxiu Li, Qiaomei Wang, Bo Sun

Journal: Genes (Basel)

PubMed ID: 34440295

Doi: 10.3390/genes12081122

Products & Services: Protein Tools

K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle

Authors: Yuanyuan Yu, Qingyun Zheng, Satchal K Erramilli, Man Pan, Seongjin Park, Yuan Xie, Jingxian Li, Jingyi Fei, Anthony A Kossiakoff, Lei Liu, Minglei Zhao

Journal: Nat Chem Biol

PubMed ID: 34239127

Doi: 10.1038/s41589-021-00823-5

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Muscone suppresses gastric cancer via regulation of miRNA-145

Authors: Feng Gao, Shihai Yan, Zheng Sun, Jia Wang

Journal: Food Sci Nutr

PubMed ID: 34531985

Doi: 10.1002/fsn3.2269

Products & Services: Gene Synthesis

The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach

Authors: Sergio Romero-Romero, Miguel Costas, Daniel-Adriano Silva Manzano, Sina Kordes, Erendira Rojas-Ortega, Cinthya Tapia, Yasel Guerra, Sooruban Shanmugaratnam, Adela Rodríguez-Romero, David Baker, Birte Höcker, D Alejandro Fernández-Velasco

Journal: J Mol Biol

PubMed ID: 34271011

Doi: 10.1016/j.jmb.2021.167153

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A Cas12a-based CRISPR interference system for multigene regulation in mycobacteria

Authors: Neil Fleck, Christoph Grundner

Journal: J Biol Chem

PubMed ID: 34298016

Doi: 10.1016/j.jbc.2021.100990

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Longitudinal evaluation of laboratory-based serological assays for SARS-CoV-2 antibody detection

Authors: K A Bond, E Williams, S Nicholson, S Lim, D Johnson, B Cox, M Putland, E Gardiner, E Tippett, M Graham, F Mordant, M Catton, S R Lewin, K Subbarao, B P Howden, D A Williamson

Journal: Pathology

PubMed ID: 34412859

Doi: 10.1016/j.pathol.2021.05.093

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Fast and reliable detection of SARS-CoV-2 antibodies based on surface plasmon resonance

Authors: Caroline Rodrigues Basso, Camila Dantas Malossi, Amanda Haisi, Valber de Albuquerque Pedrosa, Alexandre Naime Barbosa, Rejane Tommasini Grotto, João Pessoa Araujo Junior

Journal: Anal Methods

PubMed ID: 34231576

Doi: 10.1039/d1ay00737h

Products & Services: Recombinant Proteins

Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes

Authors: Lucas F de Lima, André L Ferreira, Marcelo D T Torres, William R de Araujo, Cesar de la Fuente-Nunez

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34244421

Doi: 10.1073/pnas.2106724118

Products & Services: Mammalian Expression

Selective Inhibitors of the Inducible Nitric Oxide Synthase as Modulators of Cell Responses in LPS-Stimulated Human Monocytes

Authors: Marialucia Gallorini, Monica Rapino, Helmut Schweikl, Amelia Cataldi, Rosa Amoroso, Cristina Maccallini

Journal: Molecules

PubMed ID: 34361571

Doi: 10.3390/molecules26154419

Products & Services: Proteins, Expression, Isolation and Analysis

Circular RNA Circ_0067934 Attenuates Ferroptosis of Thyroid Cancer Cells by miR-545-3p/SLC7A11 Signaling

Authors: Hui-Hui Wang, Jia-Ni Ma, Xiao-Rong Zhan

Journal: Front Endocrinol (Lausanne)

PubMed ID: 34290668

Doi: 10.3389/fendo.2021.670031

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CRISPR/Cas9-based inactivation of human papillomavirus oncogenes E6 or E7 induces senescence in cervical cancer cells

Authors: Raviteja Inturi, Per Jemth

Journal: Virology

PubMed ID: 34280810

Doi: 10.1016/j.virol.2021.07.005

Products & Services: Codon Optimization

Neutralizing Antibodies Titers and Side Effects in Response to BNT162b2 Vaccine in Healthcare Workers with and without Prior SARS-CoV-2 Infection

Authors: José Javier Morales-Núñez, José Francisco Muñoz-Valle, Carlos Meza-López, Lin-Fa Wang, Andrea Carolina Machado Sulbarán, Paola Carolina Torres-Hernández, Martín Bedolla-Barajas, Brenda De la O-Gómez, Paulina Balcázar-Félix, Jorge Hernández-Bello

Journal: Vaccines (Basel)

PubMed ID: 34358158

Doi: 10.3390/vaccines9070742

Short carboxyl terminal parathyroid hormone peptides modulate human parathyroid hormone signaling in mouse osteoblasts

Authors: Kittrawee Kritmetapak, Ravinder J Singh, Theodore A Craig, Jolaine M Hines, Rajiv Kumar

Journal: Biochem Biophys Res Commun

PubMed ID: 34332324

Doi: 10.1016/j.bbrc.2021.07.085

Products & Services: Plasmid DNA Preparation

Charting elimination in the pandemic: a SARS-CoV-2 serosurvey of blood donors in New Zealand

Authors: Lauren H Carlton, Tiffany Chen, Alana L Whitcombe, Reuben McGregor, Greg Scheurich, Campbell R Sheen, James M Dickson, Chris Bullen, Annie Chiang, Daniel J Exeter, Janine Paynter, Michael G Baker, Richard Charlewood, Nicole J Moreland

Journal: Epidemiol Infect

PubMed ID: 34668464

Doi: 10.1017/S0950268821001643

Products & Services: Recombinant Proteins

An MST4-pβ-Catenin Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis

Authors: Hui Zhang, Moubin Lin, Chao Dong, Yang Tang, Liwei An, Junyi Ju, Fuping Wen, Fan Chen, Meng Wang, Wenjia Wang, Min Chen, Yun Zhao, Jixi Li, Steven X Hou, Xinhua Lin, Lulu Hu, Wenbo Bu, Dianqing Wu, Lin Li, Shi Jiao, Zhaocai Zhou

Journal: Adv Sci (Weinh)

PubMed ID: 34240584

Doi: 10.1002/advs.202004850

Products & Services: CRISPR Libraries

Fine-tuning the expression of pathway gene in yeast using a regulatory library formed by fusing a synthetic minimal promoter with different Kozak variants

Authors: Liping Xu, Pingping Liu, Zhubo Dai, Feiyu Fan, Xueli Zhang

Journal: Microb Cell Fact

PubMed ID: 34320991

Doi: 10.1186/s12934-021-01641-z

Products & Services: Plasmid DNA Preparation

CRISPR/Cas9-mediated engineering of Escherichia coli for n-butanol production from xylose in defined medium

Authors: Ali Samy Abdelaal, Kamran Jawed, Syed Shams Yazdani

Journal: J Ind Microbiol Biotechnol

PubMed ID: 30982114

Doi: 10.1007/s10295-019-02180-8

Products & Services: Gene Synthesis

Assessment of infectivity and the impact on neutralizing activity of immune sera of the COVID-19 variant, CAL.20C

Authors: Zhongcheng Zhou, Peng Du, Meixing Yu, Daniel T. Baptista-Hon, Man Miao, Andy P. Xiang, Johnson Yiu-Nam Lau, COVID-19 Immunity Investigation Group, Gen Li, Kang Zhang

Journal: Signal transduction and targeted therapy

PubMed ID: 34315848

Doi: 10.1038/s41392-021-00695-0

Products & Services: Gene Services

Development of an Immunochromatographic Strip Using Conjugated Gold Nanoparticles for the Rapid Detection of Klebsiella pneumoniae Causing Neonatal Sepsis

Authors: Noha M. Elhosseiny, Tamer M. Samir, Aliaa A. Ali , Amani A. El‐Kholy and Ahmed S. Attia

Journal: Pharmaceutics

PubMed ID: 34452099

Doi: 10.3390/pharmaceutics13081141

Products & Services: Peptide Synthesis

Three optimized assays for the evaluation of compounds that can rescue p53 mutants

Authors: Jiale Wu, Huaxin Song, Zhengyuan Wang, Min Lu

Journal: STAR Protoc

PubMed ID: 34382015

Doi: 10.1016/j.xpro.2021.100688

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Effects of sevoflurane exposure during different stages of pregnancy on the brain development of rat offspring

Authors: Feng-He Cui, Jie Li, Ke-Zhong Li, Yong-Gang Xie, Xiao-Ling Zhao

Journal: J Anesth

PubMed ID: 34279702

Doi: 10.1007/s00540-021-02972-2

Products & Services: Recombinant Proteins

Evaluation of a novel biomarker of type XXVIII collagen formation, PRO-C28, in samples from cancer and heart failure with preserved ejection fraction patients

Authors: Alexander L Reese-Petersen, Nicholas Willumsen, Patricia Palau, Julio Nunez, Shu Sun, Tina Manon Jensen, Bibi Kamall, Morten A Karsdal, Federica Genovese

Journal: J Pharm Biomed Anal

PubMed ID: 34358813

Doi: 10.1016/j.jpba.2021.114272

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Identification of a Novel Cleavage Site and Confirmation of the Effectiveness of NgAgo Gene Editing on RNA Targets

Authors: Jiayao Qu, Yali Xie, Zhaoyi Guo, Xiangting Liu, Jing Jiang, Ting Chen, Kai Li, Zheng Hu, Dixian Luo

Journal: Mol Biotechnol

PubMed ID: 34302285

Doi: 10.1007/s12033-021-00372-1

Products & Services: Nucleic Acid Purification & Analysis

HBx represses WDR77 to enhance HBV replication by DDB1-mediated WDR77 degradation in the liver

Authors: Hongfeng Yuan, Lina Zhao, Ying Yuan, Haolin Yun, Wei Zheng, Yu Geng, Guang Yang, Yufei Wang, Man Zhao, Xiaodong Zhang

Journal: Theranostics

PubMed ID: 34373747

Doi: 10.7150/thno.57531

Products & Services: Nucleic Acid Purification & Analysis

Long-chain polyphosphates impair SARS-CoV-2 infection and replication

Authors: Veronica Ferrucci, Dae-Young Kong, Fatemeh Asadzadeh, Laura Marrone, Angelo Boccia, Roberto Siciliano, Giuseppina Criscuolo, Camilla Anastasio, Fabrizio Quarantelli, Marika Comegna, Ida Pisano, Margherita Passariello, Ilaria Iacobucci, Rosa Della Monica, Barbara Izzo, Pellegrino Cerino, Giovanna Fusco, Maurizio Viscardi, Sergio Brandi, Bianca Maria Pierri, Giorgia Borriello, Claudia Tiberio, Luigi Atripaldi, Martina Bianchi, Giovanni Paolella, Ettore Capoluongo, Giuseppe Castaldo, Lorenzo Chiariotti, Maria Monti, Claudia De Lorenzo, Kyong-Seop Yun, Stefano Pascarella, Jae-Ho Cheong, Hong-Yeoul Kim, Massimo Zollo

Journal: Sci Signal

PubMed ID: 34230209

Doi: 10.1126/scisignal.abe5040

Products & Services: Mammalian Expression

Endocytosis of peroxiredoxin 1 links sterile inflammation to immunoparalysis in pediatric patients following cardiopulmonary bypass

Authors: Chia-Hsiung Liu, Zheng-Hua Huang, Shu-Chien Huang, Tzuu-Shuh Jou

Journal: Redox Biol

PubMed ID: 34332210

Doi: 10.1016/j.redox.2021.102086

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Pancreatic Extracellular Matrix/Alginate Hydrogels Provide a Supportive Microenvironment for Insulin-Producing Cells

Authors: Dongzhi Wang, Yi Zhu, Yan Huang, Jiachen Zhu, Biwen Zhu, Yahong Zhao, Yuhua Lu, Zhiwei Wang, Yibing Guo

Journal: ACS Biomater Sci Eng

PubMed ID: 34251797

Doi: 10.1021/acsbiomaterials.1c00269

Products & Services: DNA Sequencing

Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells

Authors: Wei-Ching Chen, Minh D To, Peter M K Westcott, Reyno Delrosario, Il-Jin Kim, Mark Philips, Quan Tran, Saumya R Bollam, Hani Goodarzi, Nora Bayani, Olga Mirzoeva, Allan Balmain

Journal: Nat Commun

PubMed ID: 34257283

Doi: 10.1038/s41467-021-24498-7

Products & Services: DNA Sequencing

Topical cationic hairy particles targeting cell free DNA in dermis enhance treatment of psoriasis

Authors: Yanzi Yan, Huiyi Liang, Xingliang Liu, Lixin Liu, Yongming Chen

Journal: Biomaterials

PubMed ID: 34293700

Doi: 10.1016/j.biomaterials.2021.121027

Products & Services: DNA Sequencing

Homodimerization of a proximal region within the C-terminus of the orphan G-protein coupled receptor GPR179

Authors: Wolfrat Bachert, Lisa Klotz, Heinrich Sticht, Ralf Enz

Journal: Neurochem Int

PubMed ID: 34333057

Doi: 10.1016/j.neuint.2021.105150

Products & Services: DNA Sequencing

Differential DNA Methylation and Expression of miRNAs in Adipose Tissue From Twin Pairs Discordant for Type 2 Diabetes

Authors: Emma Nilsson, Magdalena Vavakova, Alexander Perfilyev, Johanna Säll, Per-Anders Jansson, Pernille Poulsen, Jonathan Lou S Esguerra, Lena Eliasson, Allan Vaag, Olga Göransson, Charlotte Ling

Journal: Diabetes

PubMed ID: 34315727

Doi: 10.2337/db20-0324

Products & Services: DNA Sequencing

TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway

Authors: Da-Cen Lin, Si-Yi Zheng, Zhi-Guang Zhang, Jian-Hua Luo, Zhuang-Li Zhu, Li Li, Lu-Shan Chen, Xinjian Lin, James S K Sham, Mo-Jun Lin, Rui-Xiang Zhou

Journal: Cancer Lett

PubMed ID: 34311033

Doi: 10.1016/j.canlet.2021.07.038

Products & Services: DNA Sequencing

PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis

Authors: Zili Liu, Honglin Wang, Shaoqian Wang, Jie Gao, Lei Niu

Journal: Bone Joint Res

PubMed ID: 34254815

Doi: 10.1302/2046-3758.107.BJR-2020-0200.R2

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CRISPR-/Cas12a-Mediated Liposome-Amplified Strategy for the Surface-Enhanced Raman Scattering and Naked-Eye Detection of Nucleic Acid and Application to Food Authenticity Screening

Authors: Jianghua Liu, Jiahui Chen, Di Wu, Mingquan Huang, Jian Chen, Ruiyuan Pan, Yongning Wu, Guoliang Li

Journal: Anal Chem

PubMed ID: 34278781

Doi: 10.1021/acs.analchem.1c01163

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Dual Targeting of Endoplasmic Reticulum by Redox-Deubiquitination Regulation for Cancer Therapy

Authors: Biao Cai, Mengfei Hou, Shijun Zhang, Zhixiang Xin, Jiwei Huang, Jingxing Yang, Yueming Wang, Xingyun Cai, Shaowei Xie, Chunfu Zhang, Yiran Huang

Journal: Int J Nanomedicine

PubMed ID: 34354353

Doi: 10.2147/IJN.S321612

Products & Services: Proteins, Expression, Isolation and Analysis

Overexpressed MPS-1 contributes to endometrioma development through the NF-κB signaling pathway

Authors: Yang Liu, Junyan Ma, Liqi Zhang, Jun Lin, Xiaohua Liu

Journal: Reprod Biol Endocrinol

PubMed ID: 34266426

Doi: 10.1186/s12958-021-00796-z

Products & Services: Proteins, Expression, Isolation and Analysis

Latent tuberculosis co-infection is associated with heightened levels of humoral, cytokine and acute phase responses in seropositive SARS-CoV-2 infection

Authors: Anuradha Rajamanickam, Nathella Pavan Kumar, Chandrasekaran Padmapriyadarsini, Arul Nancy, Nandhini Selvaraj, Kushiyasri Karunanithi, Saravanan Munisankar, Shrinivasa Bm, Rachel Mariam Renji, T C Ambu, Vijayalakshmi Venkataramani, Subash Babu

Journal: J Infect

PubMed ID: 34329676

Doi: 10.1016/j.jinf.2021.07.029

Products & Services: Proteins, Expression, Isolation and Analysis

Structure of a mammalian sperm cation channel complex

Authors: Shiyi Lin, Meng Ke, Yuqi Zhang, Zhen Yan, Jianping Wu

Journal: Nature

PubMed ID: 34225353

Doi: 10.1038/s41586-021-03742-6

Products & Services: Proteins, Expression, Isolation and Analysis

Epitope-Paratope Interaction of a Neutralizing Human Anti-Hepatitis B Virus PreS1 Antibody That Recognizes the Receptor-Binding Motif

Authors: Jisu Hong, Youngjin Choi, Yoonjoo Choi, Jiwoo Lee, Hyo Jeong Hong

Journal: Vaccines (Basel)

PubMed ID: 34358170

Doi: 10.3390/vaccines9070754

Products & Services: Proteins, Expression, Isolation and Analysis

Adult-born proopiomelanocortin neurons derived from Rax-expressing precursors mitigate the metabolic effects of congenital hypothalamic proopiomelanocortin deficiency

Authors: Gábor Wittmann, Malcolm J Low, Ronald M Lechan

Journal: Mol Metab

PubMed ID: 34329773

Doi: 10.1016/j.molmet.2021.101312

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Cytosolic GDH1 degradation restricts protein synthesis to sustain tumor cell survival following amino acid deprivation

Authors: Jialiang Shao, Tiezhu Shi, Hua Yu, Yufeng Ding, Liping Li, Xiang Wang, Xiongjun Wang

Journal: EMBO J

PubMed ID: 34269483

Doi: 10.15252/embj.2020107480

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Clinical utility of a serum biomarker panel in distinguishing prostate cancer from benign prostate hyperplasia

Authors: Michael A Kiebish, Poornima Tekumalla, Shobha Ravipaty, Albert Dobi, Shiv Srivastava, Wenfang Wu, Saurabh Patil, Tracey Friss, Allison Klotz, Alagarsamy Srinivasan, Jennifer Cullen, Inger L Rosner, Amina Ali, Sandra Laszlo, Michele Petrovic, Neil Fleshner, Jeonifer Garren, Greg Miller, Nischal Mahaveer Chand, Leonardo O Rodrigues, Elder Granger, Mark D Kellogg, Shen Luan, Eleftherios Diamandis, Viatcheslav R Akmaev, Rangaprasad Sarangarajan, Chas Bountra, Stephen J Freedland, David G McLeod, Niven R Narain

Journal: Sci Rep

PubMed ID: 34302010

Doi: 10.1038/s41598-021-94438-4

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Hepta-Histidine Inhibits Tau Aggregation

Authors: Kanoh Kondo, Teikichi Ikura, Hikari Tanaka, Kyota Fujita, Sumire Takayama, Yuki Yoshioka, Kazuhiko Tagawa, Hidenori Homma, Su Liu, Ryosuke Kawasaki, Yong Huang, Nobutoshi Ito, Shin-Ichi Tate, Hitoshi Okazawa

Journal: ACS Chem Neurosci

PubMed ID: 34319089

Doi: 10.1021/acschemneuro.1c00164

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The importance of vitellogenin receptors in the oviposition of the pond wolf spider, Pardosa pseudoannulata

Authors: Zhi-Ming Yang, Tian-Yu Lu, Yong Wu, Na Yu, Guang-Ming Xu, Qian-Qian Han, Ze-Wen Liu

Journal: Insect Sci

PubMed ID: 34237799

Doi: 10.1111/1744-7917.12933

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High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins

Authors: Josefien W Hommes, Rachel M Kratofil, Sigrid Wahlen, Carla J C de Haas, Reeni B Hildebrand, G Kees Hovingh, Micheal Otto, Miranda van Eck, Menno Hoekstra, Suzanne J A Korporaal, Bas G J Surewaard

Journal: Sci Rep

PubMed ID: 34321507

Doi: 10.1038/s41598-021-94651-1

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An octopamine receptor confers selective toxicity of amitraz on honeybees and mites

Authors: Lei Guo, Xin-Yu Fan, Xiaomu Qiao, Craig Montell, Jia Huang

Journal: Elife

PubMed ID: 34263722

Doi: 10.7554/eLife.68268

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Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays

Authors: Ahmed Ismail, Farah M Shurrab, Hadeel T Al-Jighefee, Duaa W Al-Sadeq, Hamda Qotba, Ibrahim Abdu Al-Shaar, Hadi M Yassine, Laith J Abu-Raddad, Gheyath K Nasrallah

Journal: Front Biosci (Landmark Ed)

PubMed ID: 34340267

Doi: 10.52586/4934

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Gadolinium-labeled affibody-XTEN recombinant vector for detection of HER2+ lesions of ovarian cancer lung metastasis using quantitative MRI

Authors: Alireza Nomani, Geng Li, Siavash Yousefi, Shawn Wu, Obeid M Malekshah, Shahryar K Nikkhoi, Mehrdad Pourfathi, Rahim Rizi, Arash Hatefi

Journal: J Control Release

PubMed ID: 34284047

Doi: 10.1016/j.jconrel.2021.07.022

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Assays for studying normal suppressive ERAD-associated retrotranslocation pathways in yeast

Authors: Satarupa Bhaduri, Sonya E Neal

Journal: STAR Protoc

PubMed ID: 34278330

Doi: 10.1016/j.xpro.2021.100640

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Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry

Authors: Alessandra Luchini, Samantha Micciulla, Giacomo Corucci, Krishna Chaithanya Batchu, Andreas Santamaria, Valerie Laux, Tamim Darwish, Robert A Russell, Michel Thepaut, Isabelle Bally, Franck Fieschi, Giovanna Fragneto

Journal: Sci Rep

PubMed ID: 34290262

Doi: 10.1038/s41598-021-93996-x

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AstraZeneca (AZD1222) Covid 19 vaccine-associated adverse drug event: a case report

Authors: Capassoni Marco, Ketabchi Sheyda, Cassisa Angelo, Caramelli Riccardo, Molinu Antonietta Anna, Galluccio Felice, Guiducci Serena

Journal: J Med Virol

PubMed ID: 34214206

Doi: 10.1002/jmv.27175

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miR-29c-3p regulates TET2 expression and inhibits autophagy process in Parkinson's disease models

Authors: Ruili Wang, Jie Yao, Fuhua Gong, Songsheng Chen, Ya He, Chunting Hu, Chen Li

Journal: Genes Cells

PubMed ID: 34086379

Doi: 10.1111/gtc.12877

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Development of a Bioluminescent Human Osteosarcoma Model in Humanized NSG Mice: A Pilot Study

Authors: Yunmi Ko, Yeon Ho Jeong, Jin-Hee Seo, Jun Ah Lee

Journal: In Vivo

PubMed ID: 34182491

Doi: 10.21873/invivo.12485

Products & Services: Proteins, Expression, Isolation and Analysis

Loss of MIC60 Aggravates Neuronal Death by Inducing Mitochondrial Dysfunction in a Rat Model of Intracerebral Hemorrhage

Authors: Ruming Deng, Wenjie Wang, Xiang Xu, Jiasheng Ding, Jiahe Wang, Siyuan Yang, Haiying Li, Haitao Shen, Xiang Li, Gang Chen

Journal: Mol Neurobiol

PubMed ID: 34232477

Doi: 10.1007/s12035-021-02468-w

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PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging

Authors: Anna S Kirstein, Stephanie Kehr, Michèle Nebe, Martha Hanschkow, Lisa A G Barth, Judith Lorenz, Melanie Penke, Jana Breitfeld, Diana Le Duc, Kathrin Landgraf, Antje Körner, Peter Kovacs, Peter F Stadler, Wieland Kiess, Antje Garten

Journal: J Biol Chem

PubMed ID: 34273354

Doi: 10.1016/j.jbc.2021.100968

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Longitudinal variation in SARS-CoV-2 antibody levels and emergence of viral variants: implications for the ability of serological assays to predict immunity

Authors: Frauke Muecksch, Helen Wise, Kate Templeton, Becky Batchelor, Maria Squires, Kirsty McCance, Lisa Jarvis, Kristen Malloy, Elizabeth Furrie, Claire Richardson, Jacqueline MacGuire, Ian Godber, Alana Burns, Sally Mavin, Fengwen Zhang, Fabian Schmidt, Paul Bieniasz, Sara Jenks, Theodora Hatziioannou

Journal: medrxiv

PubMed ID: 34268524

Doi: 10.1101/2021.07.02.21259939

Single-chain Fragment variable antibody targeting cholecystokinin-B receptor for pain reduction

Authors: K N Westlund, M A Montera, A E Goins, S R A Alles, M Afaghpour-Becklund, R Bartel, R Durvasula, A Kunamneni

Journal: Neurobiol Pain

PubMed ID: 34458647

Doi: 10.1016/j.ynpai.2021.100067

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The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response

Authors: Bo Liu, Jiancheng Huang, Amina Ashraf, Oindrila Rahaman, Jing Lou, Ling Wang, Peiliang Cai, Jinping Wen, Shoaib Anwaar, Xiaoli Liu, Hai Ni, Dipyaman Ganguly, Jijun Zhao, Cliff Y Yang

Journal: Nat Commun

PubMed ID: 34215755

Doi: 10.1038/s41467-021-24352-w

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Genome-wide identification of candidate aquaporins involved in water accumulation of pomegranate outer seed coat

Authors: Jianjian Liu, Gaihua Qin, Chunyan Liu, Xiuli Liu, Jie Zhou, Jiyu Li, Bingxin Lu, Jianrong Zhao

Journal: PeerJ

PubMed ID: 34316414

Doi: 10.7717/peerj.11810

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Screening New Xylanase Biocatalysts from the Mangrove Soil Diversity

Authors: Corinne Ivaldi, Mariane Daou, Laurent Vallon, Alexandra Bisotto, Mireille Haon, Sona Garajova, Emmanuel Bertrand, Craig B Faulds, Giuliano Sciara, Adrien Jacotot, Cyril Marchand, Mylène Hugoni, Harivony Rakotoarivonina, Marie-Noëlle Rosso, Caroline Rémond, Patricia Luis, Eric Record

Journal: Microorganisms

PubMed ID: 34361919

Doi: 10.3390/microorganisms9071484

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Tobacco BY2 cells expressing recombinant cardosin B as an alternative for production of active milk clotting enzymes

Authors: André Folgado, Rita Abranches

Journal: Sci Rep

PubMed ID: 34262119

Doi: 10.1038/s41598-021-93882-6

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Heat-dependent opening of TRPV1 in the presence of capsaicin

Authors: Do Hoon Kwon, Feng Zhang, Yang Suo, Jonathan Bouvette, Mario J Borgnia, Seok-Yong Lee

Journal: Nat Struct Mol Biol

PubMed ID: 34239123

Doi: 10.1038/s41594-021-00616-3

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The upstream 5' splice site remains associated to the transcription machinery during intron synthesis

Authors: Yodfat Leader, Galit Lev Maor, Matan Sorek, Ronna Shayevitch, Maram Hussein, Ofir Hameiri, Luna Tammer, Jonathan Zonszain, Ifat Keydar, Dror Hollander, Eran Meshorer, Gil Ast

Journal: Nat Commun

PubMed ID: 34315864

Doi: 10.1038/s41467-021-24774-6

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Low neutralizing antibody responses in WM, CLL and NHL patients after the first dose of the BNT162b2 and AZD1222 vaccine

Authors: Maria Gavriatopoulou, Evangelos Terpos, Efstathios Kastritis, Alexandros Briasoulis, Sentiljana Gumeni, Ioannis Ntanasis-Stathopoulos, Aimilia D Sklirou, Panagiotis Malandrakis, Evangelos Eleutherakis-Papaiakovou, Magdalini Migkou, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Clin Exp Med

PubMed ID: 34283338

Doi: 10.1007/s10238-021-00746-4

Overexpression of Douglas-Fir () in Induces Embryonic Programs and Embryo-like Structures in the Mutant but Not in Wild Type Plants

Authors: Mariana A Vetrici, Dmytro P Yevtushenko, Santosh Misra

Journal: Plants (Basel)

PubMed ID: 34451571

Doi: 10.3390/plants10081526

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Integrated workflow for urinary prostate specific antigen N-glycosylation analysis using sdAb partitioning and downstream capillary electrophoresis separation

Authors: Balazs Reider, Eszter Gacsi, Hajnalka Jankovics, Ferenc Vonderviszt, Tibor Szarvas, Andras Guttman, Gabor Jarvas

Journal: Anal Chim Acta

PubMed ID: 34625256

Doi: 10.1016/j.aca.2021.338892

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Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

Authors: Jérémie Prévost, Jonathan Richard, Romain Gasser, Shilei Ding, Clément Fage, Sai Priya Anand, Damien Adam, Natasha Gupta Vergara, Alexandra Tauzin, Mehdi Benlarbi, Shang Yu Gong, Guillaume Goyette, Anik Privé, Sandrine Moreira, Hugues Charest, Michel Roger, Walther Mothes, Marzena Pazgier, Emmanuelle Brochiero, Guy Boivin, Cameron F Abrams, Arne Schön, Andrés Finzi

Journal: biorxiv

PubMed ID: 34268505

Doi: 10.1101/2021.07.09.451812

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Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration

Authors: Hao Huang, Alexander Gont, Lynn Kee, Ruben Dries, Kathrin Pfeifer, Bandana Sharma, David N Debruyne, Matthew Harlow, Satyaki Sengupta, Jikui Guan, Caleb M Yeung, Wenchao Wang, Bengt Hallberg, Ruth H Palmer, Meredith S Irwin, Rani E George

Journal: Cell Rep

PubMed ID: 34260934

Doi: 10.1016/j.celrep.2021.109363

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LncRNA HOXA11-AS promotes cell growth by sponging miR-24-3p to regulate JPT1 in prostate cancer

Authors: Y Cheng, H-Y Xiong, Y-M Li, H-R Zuo, Y Liu, G-L Liao

Journal: Eur Rev Med Pharmacol Sci

PubMed ID: 34337714

Doi: 10.26355/eurrev_202107_26377

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Association of total and neutralizing SARS-CoV-2 spike -receptor binding domain antibodies with epidemiological and clinical characteristics after immunization with the 1 and 2 doses of the BNT162b2 vaccine

Authors: Athanasios Michos, Elizabeth-Barbara Tatsi, Filippos Filippatos, Charilaos Dellis, Dimitra Koukou, Vasiliki Efthymiou, Evangelia Kastrinelli, Aimilia Mantzou, Vasiliki Syriopoulou

Journal: Vaccine

PubMed ID: 34400017

Doi: 10.1016/j.vaccine.2021.07.067

An increase in VGF expression through a rapid, transcription-independent, autofeedback mechanism improves cognitive function

Authors: Wei-Jye Lin, Yan Zhao, Zhe Li, Shuyu Zheng, Jin-Lin Zou, Noël A Warren, Purva Bali, Jingru Wu, Mengdan Xing, Cheng Jiang, Yamei Tang, Stephen R Salton, Xiaojing Ye

Journal: Transl Psychiatry

PubMed ID: 34238925

Doi: 10.1038/s41398-021-01489-2

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Activation of Adenosine A Receptor in Ischemic Stroke: Neuroprotection by Tetrahydroxy Stilbene Glycoside as an Agonist

Authors: Lingyu Ruan, Guanghui Li, Wenlong Zhao, Huihui Meng, Qi Zheng, Junsong Wang

Journal: Antioxidants (Basel)

PubMed ID: 34356346

Doi: 10.3390/antiox10071112

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Differential Modulation of Heat-Inducible Genes Across Diverse Genotypes and Molecular Cloning of a sHSP From Pearl Millet [ (L) R Br]

Authors: S Mukesh Sankar, C Tara Satyavathi, Sharmistha Barthakur, Sumer Pal Singh, C Bharadwaj, S L Soumya

Journal: Front Plant Sci

PubMed ID: 34335644

Doi: 10.3389/fpls.2021.659893

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Introduction of the Carotenoid Biosynthesis α-Branch Into sp PCC 6803 for Lutein Production

Authors: Martin Lehmann, Evgenia Vamvaka, Alejandro Torrado, Peter Jahns, Marcel Dann, Lea Rosenhammer, Amel Aziba, Dario Leister, Thilo Rühle

Journal: Front Plant Sci

PubMed ID: 34295345

Doi: 10.3389/fpls.2021.699424

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The B-cell Receptor Autoantigen LRPAP1 Can Replace Variable Antibody Regions to Target Mantle Cell Lymphoma Cells

Authors: Moritz Bewarder, Maximilian Kiefer, Helene Will, Kathrin Olesch, Clara Moelle, Stephan Stilgenbauer, Konstantinos Christofyllakis, Dominic Kaddu-Mulindwa, Joerg Thomas Bittenbring, Natalie Fadle, Evi Regitz, Lea Kaschek, Markus Hoth, Frank Neumann, Klaus-Dieter Preuss, Michael Pfreundschuh, Lorenz Thurner

Journal: HemaSphere

PubMed ID: 34263144

Doi: 10.1097/HS9.0000000000000620

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Persistent symptoms in adult patients one year after COVID-19: a prospective cohort study

Authors: Jessica Seeßle, Tim Waterboer, Theresa Hippchen, Julia Simon, Marietta Kirchner, Adeline Lim, Barbara Müller, Uta Merle

Journal: Clin Infect Dis

PubMed ID: 34223884

Doi: 10.1093/cid/ciab611

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Antibody Response After Initial Vaccination for SARS-CoV-2 in Patients With Amyloidosis

Authors: Efstathios Kastritis, Evangelos Terpos, Aimilia Sklirou, Foteini Theodorakakou, Despina Fotiou, Eleni-Dimitra Papanagnou, Tina Bagratuni, Nikolaos Kanellias, Maria Gavriatopoulou, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: HemaSphere

PubMed ID: 34278231

Doi: 10.1097/HS9.0000000000000614

Human Hyaluronidase PH20 Potentiates the Antitumor Activities of Mesothelin-Specific CAR-T Cells Against Gastric Cancer

Authors: Ruocong Zhao, Yuanbin Cui, Yongfang Zheng, Shanglin Li, Jiang Lv, Qiting Wu, Youguo Long, Suna Wang, Yao Yao, Wei Wei, Jie Yang, Bin-Chao Wang, Zhenfeng Zhang, Hui Zeng, Yangqiu Li, Peng Li

Journal: Front Immunol

PubMed ID: 34326835

Doi: 10.3389/fimmu.2021.660488

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High Prevalence of Anti-PF4 Antibodies Following ChAdOx1 nCov-19 (AZD1222) Vaccination Even in the Absence of Thrombotic Events

Authors: Evangelos Terpos, Marianna Politou, Ioannis Ntanasis-Stathopoulos, Vangelis Karalis, Efrosyni Merkouri, Despina Fotiou, Maria Gavriatopoulou, Panagiotis Malandrakis, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Vaccines (Basel)

PubMed ID: 34358129

Doi: 10.3390/vaccines9070712

Surveillance of Borrelia miyamotoi-carrying ticks and genomic analysis of isolates in Inner Mongolia, China

Authors: Kozue Sato, Dan Liu, Yunhong Cui, Xuhong Yin, Lihua Zhang, Hong Li, Tingfu Wang, Rongxin Liu, Lijing Wu, Saixia Lu, Ting Gao, Zitong Zhang, Minzhi Cao, Guodong Wang, Chunpu Li, Dacheng Yan, Norio Ohashi, Shuji Ando, Hiroki Kawabata

Journal: Parasit Vectors

PubMed ID: 34274015

Doi: 10.1186/s13071-021-04809-z

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Host-interactor screens of Phytophthora infestans RXLR proteins reveal vesicle trafficking as a major effector-targeted process

Authors: Benjamin Petre, Mauricio P Contreras, Tolga O Bozkurt, Martin H Schattat, Jan Sklenar, Sebastian Schornack, Ahmed Abd-El-Haliem, Roger Castells-Graells, Rosa Lozano-Durán, Yasin F Dagdas, Frank L H Menke, Alexandra M E Jones, Jack H Vossen, Silke Robatzek, Sophien Kamoun, Joe Win

Journal: Plant Cell

PubMed ID: 33677602

Doi: 10.1093/plcell/koab069

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Neutrophil elastase promotes neointimal hyperplasia by targeting toll-like receptor 4 (TLR4)-NF-κB signalling

Authors: Mei Yang, Qishan Chen, Li Mei, Guanmei Wen, Weiwei An, Xinmiao Zhou, Kaiyuan Niu, Chenxin Liu, Meixia Ren, Kun Sun, Qingzhong Xiao, Li Zhang

Journal: Br J Pharmacol

PubMed ID: 34076894

Doi: 10.1111/bph.15583

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SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses

Authors: George W Carnell, Katarzyna A Ciazynska, David A Wells, Xiaoli Xiong, Ernest T Aguinam, Stephen H McLaughlin, Donna Mallery, Soraya Ebrahimi, Lourdes Ceron-Gutierrez, Benedikt Asbach, Sebastian Einhauser, Ralf Wagner, Leo C James, Rainer Doffinger, Jonathan L Heeney, John A G Briggs

Journal: J Virol

PubMed ID: 33963055

Doi: 10.1128/JVI.00203-21

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Effective Antitumor of Orally Intestinal Targeting Penetrating Peptide-Loaded Tyroserleutide/PLGA Nanoparticles in Hepatocellular Carcinoma

Authors: Chenjun Ma, Tiantian Wei, Yingying Hua, Zhongjie Wang, Liefeng Zhang

Journal: Int J Nanomedicine

PubMed ID: 34239301

Doi: 10.2147/IJN.S315713

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P2X7R in Mast Cells is a Potential Target for Salicylic Acid and Aspirin in Treatment of Inflammatory Pain

Authors: Yucui Jiang, Fan Ye, Ying Du, Yingxin Zong, Zongxiang Tang

Journal: J Inflamm Res

PubMed ID: 34239315

Doi: 10.2147/JIR.S313348

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Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism

Authors: Fumika Ochiai-Homma, Emiko Kuribayashi-Okuma, Yuya Tsurutani, Kenichi Ishizawa, Wataru Fujii, Kohei Odajima, Mika Kawagoe, Yoshihiro Tomomitsu, Masataka Murakawa, Shinichiro Asakawa, Daigoro Hirohama, Michito Nagura, Shigeyuki Arai, Osamu Yamazaki, Yoshifuru Tamura, Yoshihide Fujigaki, Tetsuo Nishikawa, Shigeru Shibata

Journal: Hypertens Res

PubMed ID: 34326480

Doi: 10.1038/s41440-021-00710-5

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Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy

Authors: Katherine W Cook, Wei Xue, Peter Symonds, Ian Daniels, Mohamed Gijon, David Boocock, Clare Coveney, Amanda K Miles, Sabaria Shah, Suha Atabani, Ruhul H Choudhury, Poonam Vaghela, Daisy Weston, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal: J Immunother Cancer

PubMed ID: 34321274

Doi: 10.1136/jitc-2020-001910

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A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in

Authors: Dayana C Farhat, Matthew W Bowler, Guillaume Communie, Dominique Pontier, Lucid Belmudes, Caroline Mas, Charlotte Corrao, Yohann Couté, Alexandre Bougdour, Thierry Lagrange, Mohamed-Ali Hakimi, Christopher Swale

Journal: Elife

PubMed ID: 34263725

Doi: 10.7554/eLife.68312

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ACTH treatment promotes murine cardiac allograft acceptance

Authors: Jing Zhao, Liwei Jiang, Mayuko Uehara, Naima Banouni, Basmah S Al Dulaijan, Jamil Azzi, Takaharu Ichimura, Xiaofei Li, Petr Jarolim, Paolo Fiorina, Stefan G Tullius, Joren C Madsen, Vivek Kasinath, Reza Abdi

Journal: JCI Insight

PubMed ID: 34236047

Doi: 10.1172/jci.insight.143385

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Low efficiency of leucocyte plugging-based drug delivery to cancer in mice

Authors: Baifeng Qian, Andreas Termer, Christof M Sommer, Arianeb Mehrabi, Eduard Ryschich

Journal: Drug Deliv Transl Res

PubMed ID: 34319578

Doi: 10.1007/s13346-021-01028-y

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