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Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A

Authors: Dell'Orco D, Dal Cortivo G.

Journal: Sci Rep

PubMed ID: 31882816

Doi: 10.1038/s41598-019-56606-5

Products & Services: Gene Synthesis Gene Synthesis

Reduced sensitivity of the SARS-CoV-2 Lambda variant to monoclonal antibodies and neutralizing antibodies induced by infection and vaccination

Authors: Meiyu Wang, Li Zhang, Qianqian Li, Bo Wang, Ziteng Liang, Yeqing Sun, Jianhui Nie, Jiajing Wu, Xiaodong Su, Xiaowang Qu, Yuhua Li, Youchun Wang, Weijin Huang

Journal: Emerg Microbes Infect

PubMed ID: 34818119

Doi: 10.1080/22221751.2021.2008775

Products & Services: Peptide Synthesis

Autophagy protein LC3C binding to phospholipid and interaction with lipid membranes.

Authors: Uxue Ballesteros , Asier Etxaniz , Marina N Iriondo , Yaiza R Varela , Melisa Lázaro , Ana R Viguera , L Ruth Montes , Mikel Valle , Félix M Goñi , Alicia Alonso

Journal: Int J Biol Macromol

PubMed ID: 35618088

Doi: 10.1016/j.ijbiomac.2022.05.129.

Products & Services: Mutagenesis Services

Optimization and validation of CAR transduction into human primary NK cells using CRISPR and AAV

Authors: Meisam Naeimi Kararoudi, Shibi Likhite, Ezgi Elmas, ..., Branden S. Moriarity, Kathrin Meyer, Dean A. Lee

Journal: CellPress

Doi: crmeth.2022.100236

Products & Services: Plasmid DNA Preparation

Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway.

Authors: Shenglong Zhu, Jingwei Zhang, Xuan Jiang, Wei Wang, Yong Q Chen

Journal: EBioMedicine

PubMed ID: 35588628

Doi: 10.1016/j.ebiom.2022.104060

Products & Services: PCR Cloning and Subcloning

Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain

Authors: Airah Javorsky, Patrick O Humbert , Marc Kvansakul

Journal: Commun Biol

PubMed ID: 34117354

Doi: 10.1038/s42003-021-02250-7

Products & Services: Codon Optimization

SpG and SpRY variants expand the CRISPR toolbox for genome editing in zebraﬁsh

Authors: Fang Liang, Yu Zhang, Lin Li, Yexin Yang, Ji-Feng Fei, Yanmei Liu, Wei Qin

Journal: Nat Commun

PubMed ID: 35701400

Doi: 10.1038/s41467-022-31034-8

Products & Services: Synthetic sgRNA and crRNA Service

An in-library ligation strategy and its application in CRISPR/Cas9 screening of high-order gRNA combinations

Authors: Zhike Lu, Ke Ni, Yingying Wang, Yangfan Zhou, Yini Li, Jianfeng Yan, Qingkai Song, Min Liu, Yujun Xu, Zhenxing Yu, Tiannan Guo and Lijia Ma

Journal: Nucleic Acids Res

PubMed ID: 35670669

Doi: 10.1093/nar/gkac458

Products & Services: Oligo pool

Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376

Authors: Xiao-dong Luan, Bin-xian Chen, Wei-juan Shang , Wan-chao Yin , Ye Jin , Lei-ke Zhang , H. Eric Xu and Shu-yang Zhang

Journal: acta pharmacologica sinica

Doi: 10.1038/s41401-022-00929-z

Products & Services: Gene Synthesis

Missense mutations affecting Ca-coordination in GCAP1 lead to cone-rod dystrophies by altering protein structural and functional properties

Authors: Giuditta Dal Cortivo, Valerio Marino, Francesco Bonì, Mario Milani, Daniele Dell'Orco

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 32650103

Doi: 10.1016/j.bbamcr.2020.118794

Products & Services: PCR Cloning and Subcloning Gene Synthesis

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