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Sequential dynamics of virological and serological changes in the serum of SARS-CoV-2 infected patients

Authors: Serge Ouoba, Mafumi Okimoto, Shintaro Nagashima, Yoshihiro Kitahara, Kei Miwata, Ko Ko, Bunthen E, Aya Sugiyama, Kazuaki Takahashi, Takemasa Sakaguchi, Toshiro Takafuta, Junko Tanaka

Journal: J Med Virol

PubMed ID: 34897741

Doi: 10.1002/jmv.27518

Products & Services: Protein and Antibody Reagents

Cell-Penetrating Antimicrobial Peptides Derived from an Atypical Staphylococcal δ-Toxin

Authors: Kathyana Deeyagahage, Antonio Ruzzini

Journal: Microbiol Spectr

PubMed ID: 34937169

Doi: 10.1128/spectrum.01584-21

Products & Services: Peptide Synthesis

SARS-CoV-2 prevalence and immunity: a hospital-based study from Malawi

Authors: C Meinus, R Singer, B Nandi, O Jagot, B Becker-Ziaja, B Karo, B Mvula, A Jansen, J Baumann, A Schultz

Journal: Int J Infect Dis

PubMed ID: 34929356

Doi: 10.1016/j.ijid.2021.12.336

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Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine (CoronaVac) in inadvertently vaccinated healthy children

Authors: Eder Gatti Fernandes, Giselle Ibette Silva López-Lopes, Valeria Oliveira Silva, Rosemeire Yamashiro, Karen Cristina Rolim Madureira, Juliana Failde Gallo, José Angelo Lindoso, Helena Keico Sato, Núbia Virginia D'Avila Limeira de Araujo, Maria Ligia Bacciotte Ramos Nerger, Luis Fernando Macedo Brigido

Journal: Rev Inst Med Trop Sao Paulo

PubMed ID: 34878041

Doi: 10.1590/S1678-9946202163083

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Inhibition of micro RNA miR-122-5p prevents lipopolysaccharide-induced myocardial injury by inhibiting oxidative stress, inflammation and apoptosis via targeting GIT1

Authors: Wenliang Song, Tiening Zhang, Ni Yang, Tao Zhang, Ri Wen, Chunfeng Liu

Journal: Bioengineered

PubMed ID: 34002676

Doi: 10.1080/21655979.2021.1926201

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De novo design of a transcription factor for a progesterone biosensor

Authors: Kun Liu, Yunsen Zhang, Ke Liu, Yunqiu Zhao, Bei Gao, Xinyi Tao, Ming Zhao, Feng-Qing Wang, Dongzhi Wei

Journal: Biosens Bioelectron

PubMed ID: 35134684

Doi: 10.1016/j.bios.2021.113897

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Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

Authors: Zhenghai Tang, Dominique Davidson, Rui Li, Ming-Chao Zhong, Jin Qian, Jun Chen, André Veillette

Journal: Cell Rep

PubMed ID: 34910922

Doi: 10.1016/j.celrep.2021.110111

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The protective effects of S14G-humanin (HNG) against lipopolysaccharide (LPS)- induced inflammatory response in human dental pulp cells (hDPCs) mediated by the TLR4/MyD88/NF-κB pathway

Authors: Ping Zhang, Zhiqiang Cui, Shuai Li

Journal: Bioengineered

PubMed ID: 34605740

Doi: 10.1080/21655979.2021.1979914

Products & Services: Mammalian Expression

Cabergoline possesses a beneficial effect on blood-brain barrier (BBB) integrity against lipopolysaccharide (LPS)

Authors: Lina You, Haidong Jiang

Journal: Bioengineered

PubMed ID: 34592907

Doi: 10.1080/21655979.2021.1987066

Products & Services: Plasmid DNA Preparation

ER proteins decipher the tubulin code to regulate organelle distribution

Authors: Pengli Zheng, Christopher J Obara, Ewa Szczesna, Jonathon Nixon-Abell, Kishore K Mahalingan, Antonina Roll-Mecak, Jennifer Lippincott-Schwartz, Craig Blackstone

Journal: Nature

PubMed ID: 34912111

Doi: 10.1038/s41586-021-04204-9

Products & Services: Mutant Libraries

Multiplexed CRISPR-mediated engineering of protein secretory pathway genes in the thermotolerant methylotrophic yeast Ogataea thermomethanolica

Authors: Worarat Kruasuwan, Aekkachai Puseenam, Sutipa Tanapongpipat, Niran Roongsawang

Journal: PLoS ONE

PubMed ID: 34941944

Doi: 10.1371/journal.pone.0261754

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Cell Surface SARS-CoV-2 Nucleocapsid Protein Modulates Innate and Adaptive Immunity

Authors: Alberto Domingo López-Muñoz, Ivan Kosik, Jaroslav Holly, Jonathan W Yewdell

Journal: biorxiv

PubMed ID: 34931195

Doi: 10.1101/2021.12.10.472169

Products & Services: Mammalian Expression

A single-nucleotide mutation within the TBX3 enhancer increased body size in Chinese horses

Authors: Xuexue Liu, Yanli Zhang, Wujun Liu, Yefang Li, Jianfei Pan, Yabin Pu, Jianlin Han, Ludovic Orlando, Yuehui Ma, Lin Jiang

Journal: Curr Biol

PubMed ID: 34906355

Doi: 10.1016/j.cub.2021.11.052

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Kinetic Characterization of Human Histone Deacetylase 8 With Medium-Chain Fatty Acyl Lysine

Authors: Harrison Yoo, Gregory A Polsinelli

Journal: Epigenet Insights

PubMed ID: 34917889

Doi: 10.1177/25168657211065685

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SARS-CoV-2-triggered mast cell rapid degranulation induces alveolar epithelial inflammation and lung injury

Authors: Meng-Li Wu, Feng-Liang Liu, Jing Sun, Xin Li, Xiao-Yan He, Hong-Yi Zheng, Yan-Heng Zhou, Qihong Yan, Ling Chen, Guo-Ying Yu, Junbiao Chang, Xia Jin, Jincun Zhao, Xin-Wen Chen, Yong-Tang Zheng, Jian-Hua Wang

Journal: Signal Transduct Target Ther

PubMed ID: 34921131

Doi: 10.1038/s41392-021-00849-0

Products & Services: Protein and Antibody Isolation

Effect of human secretory calcium-binding phosphoprotein proline-glutamine rich 1 protein on Porphyromonas gingivalis and identification of its active portions

Authors: Charline Mary, Aurélien Fouillen, Pierre Moffatt, Dainelys Guadarrama Bello, Rima M Wazen, Daniel Grenier, Antonio Nanci

Journal: Sci Rep

PubMed ID: 34887426

Doi: 10.1038/s41598-021-02661-w

Products & Services: Mammalian Expression

KRas-transformed epithelia cells invade and partially dedifferentiate by basal cell extrusion

Authors: John Fadul, Teresa Zulueta-Coarasa, Gloria M Slattum, Nadja M Redd, Mauricio Franco Jin, Michael J Redd, Stephan Daetwyler, Danielle Hedeen, Jan Huisken, Jody Rosenblatt

Journal: Nat Commun

PubMed ID: 34893591

Doi: 10.1038/s41467-021-27513-z

Products & Services: PCR Cloning and Subcloning

RGEN-seq for highly sensitive amplification-free screen of off-target sites of gene editors

Authors: Alexander Kuzin, Brendan Redler, Jaya Onuska, Alexei Slesarev

Journal: Sci Rep

PubMed ID: 34880355

Doi: 10.1038/s41598-021-03160-8

Products & Services: Mammalian Expression

Nonmuscle myosin heavy chain IIA facilitates SARS-CoV-2 infection in human pulmonary cells

Authors: Jian Chen, Jun Fan, Zhilu Chen, Miaomiao Zhang, Haoran Peng, Jian Liu, Longfei Ding, Mingbin Liu, Chen Zhao, Ping Zhao, Shuye Zhang, Xiaoyan Zhang, Jianqing Xu

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34873039

Doi: 10.1073/pnas.2111011118

Products & Services: Plasmid DNA Preparation

Structure, mechanism, and inhibition of Hedgehog acyltransferase

Authors: Claire E Coupland, Sebastian A Andrei, T Bertie Ansell, Loic Carrique, Pramod Kumar, Lea Sefer, Rebekka A Schwab, Eamon F X Byrne, Els Pardon, Jan Steyaert, Anthony I Magee, Thomas Lanyon-Hogg, Mark S P Sansom, Edward W Tate, Christian Siebold

Journal: Mol Cell

PubMed ID: 34890564

Doi: 10.1016/j.molcel.2021.11.018

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African Swine Fever Virus cysteine protease pS273R Inhibits Pyroptosis by Non-canonically Cleaving Gasdermin D

Authors: Gaihong Zhao, Tingting Li, Xuemin Liu, Taoqing Zhang, Zhaoxia Zhang, Li Kang, Jie Song, Shijun Zhou, Xin Chen, Xiao Wang, Jiangnan Li, Li Huang, Changyao Li, Zhigao Bu, Jun Zheng, Changjiang Weng

Journal: J Biol Chem

PubMed ID: 34890644

Doi: 10.1016/j.jbc.2021.101480

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MVA vector expression of SARS-CoV-2 spike protein and protection of adult Syrian hamsters against SARS-CoV-2 challenge

Authors: Clement A Meseda, Charles B Stauft, Prabhuanand Selvaraj, Christopher Z Lien, Cyntia Pedro, Ivette A Nuñez, Amy M Woerner, Tony T Wang, Jerry P Weir

Journal: npj Vaccines

PubMed ID: 34862398

Doi: 10.1038/s41541-021-00410-8

Products & Services: Protein and Antibody Isolation

Analysis of CcGASA family members in Citrus clementina (Hort ex Tan) by a genome-wide approach

Authors: Tianli Wu, Yun Zhong, Min Chen, Bo Wu, Ting Wang, Bo Jiang, Guangyan Zhong

Journal: BMC Plant Biol

PubMed ID: 34852791

Doi: 10.1186/s12870-021-03326-6

Products & Services: Protein Tools

The microtubule-associated protein She1 coordinates directional spindle positioning by spatially restricting dynein activity

Authors: Kari H Ecklund, Megan E Bailey, Kelly A Kossen, Carsten K Dietvorst, Charles L Asbury, Steven M Markus

Journal: J Cell Sci

PubMed ID: 34854468

Doi: 10.1242/jcs.258510

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Cloning and Characterization of Two Putative P-Type ATPases from the Marine Microalga Similar to Plant H-ATPases and Their Gene Expression Analysis under Conditions of Hyperosmotic Salt Shock

Authors: Dmitrii A Matalin, Dmitrii E Khramov, Alexey V Shuvalov, Vadim S Volkov, Yurii V Balnokin, Larissa G Popova

Journal: Plants (Basel)

PubMed ID: 34961138

Doi: 10.3390/plants10122667

Products & Services: Protein Tools

Safety evaluation of the mouse TCRα - transduced T cell product in preclinical models in vivo and in vitro

Authors: Anastasiia Kalinina, Alexandra Bruter, Nadezhda Persiyantseva, Yulia Silaeva, Maria Zamkova, Ludmila Khromykh, Dmitry Kazansky

Journal: Biomed Pharmacother

PubMed ID: 34915667

Doi: 10.1016/j.biopha.2021.112480

Products & Services: Molecular Biology Reagents

Design of Mimetic Antibodies Targeting the SARS-CoV-2 Spike Glycoprotein Based on the GB1 Domain: A Molecular Simulation and Experimental Study

Authors: Anderson A. E Santo; Aline Reis; Anderson A. Pinheiro; Paulo I. da Costa; Gustavo T. Feliciano

Journal: Biochemistry

PubMed ID: 40096593

Doi: 10.1021/acs.biochem.4c00671

Construction, expression, purification, characterization, and structural analysis of microbial transglutaminase variants

Authors: Xiaoping Song, Hefang Sheng, Yueqiao Zhou, Yin Yu, Yingjiao He, Zihan Wang

Journal: Biotechnol Appl Biochem

PubMed ID: 34894362

Doi: 10.1002/bab.2298

Products & Services: Recombinant Antibody Expression

Edaravone Improves the Post-traumatic Brain Injury Dysfunction in Learning and Memory by Modulating Nrf2/ARE Signal Pathway

Authors: Xiushan Li, Jing Yu, Dongzhou Ma, Xuehui Weng

Journal: Clinics (Sao Paulo)

PubMed ID: 34878029

Doi: 10.6061/clinics/2021/e3131

Products & Services: Plasmid DNA Preparation

Biomaterial-mediated presentation of wnt5a mimetic ligands enhances chondrogenesis and metabolism of stem cells by activating non-canonical Wnt signaling

Authors: Yingrui Deng, Xiaoting Zhang, Rui Li, Zhuo Li, Boguang Yang, Peng Shi, Honglu Zhang, Chunming Wang, Chunyi Wen, Gang Li, Liming Bian

Journal: Biomaterials

PubMed ID: 34959028

Doi: 10.1016/j.biomaterials.2021.121316

Products & Services: Protein and Antibody Isolation

Tanshinone IIA sodium sulfonate attenuates inflammation by upregulating circ-Sirt1 and inhibiting the entry of NF-κB into the nucleus

Authors: Jiao Lan, Ke Li, Austin Gresham, Jifei Miao

Journal: Eur J Pharmacol

PubMed ID: 34896110

Doi: 10.1016/j.ejphar.2021.174693

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KIAA1217 Promotes Epithelial-Mesenchymal Transition and Hepatocellular Carcinoma Metastasis by Interacting with and Activating STAT3

Authors: Yanhong Wang, Na Li, Yanping Zheng, Anqing Wang, Chunlei Yu, Zhenbo Song, Shuyue Wang, Ying Sun, Lihua Zheng, Guannan Wang, Lei Liu, Jingwen Yi, Yanxin Huang, Muqing Zhang, Yongli Bao, Luguo Sun

Journal: Int J Mol Sci

PubMed ID: 35008530

Doi: 10.3390/ijms23010104

Products & Services: Plasmid DNA Preparation

Exposure to in Asian Elephants () in Thailand

Authors: Ruenruetai Udonsom, Yoshifumi Nishikawa, Ragab M Fereig, Thitirat Topisit, Natchakorn Kulkaweewut, Supitcha Chanamrung, Charoonluk Jirapattharasate

Journal: Pathogens

PubMed ID: 35055950

Doi: 10.3390/pathogens11010002

Products & Services: Protein and Antibody Isolation

Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men

Authors: Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong

Journal: Emerg Microbes Infect

PubMed ID: 34709140

Doi: 10.1080/22221751.2021.1999777

The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling

Authors: Xihua Wang, Shuyuan Guan, Lingbin Sun, Zhongliang Dai

Journal: Environ Toxicol Pharmacol

PubMed ID: 34883242

Doi: 10.1016/j.etap.2021.103782

Products & Services: Protein and Antibody Isolation

Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

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Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

Products & Services: Protein Tools

Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

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Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

Products & Services: Peptide Synthesis

CASP5 and CR1 as potential biomarkers for Kawasaki disease: an Integrated Bioinformatics-Experimental Study

Authors: Yazdan Rahmati, Hasan Mollanoori, Sajad Najafi, Sajjad Esmaeili, Mohammad Reza Alivand

Journal: BMC Pediatr

PubMed ID: 34895171

Doi: 10.1186/s12887-021-03003-5

Products & Services: Molecular Biology Tools

Key factors determining competitions between double-stranded RNAs in Tribolium castaneum

Authors: Xu Shen, Yingchuan Peng, Huifang Song, Jinda Wang, Jun Zhao, Peian Tang, Zhaojun Han, Kangxu Wang

Journal: Pestic Biochem Physiol

PubMed ID: 35082032

Doi: 10.1016/j.pestbp.2021.105009

Products & Services: Gene Synthesis

Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro

Authors: Lin Chen, Zhi-Qiang Pan, Chang-Bin Zhai

Journal: Folia Histochem Cytobiol

PubMed ID: 34905214

Doi: 10.5603/FHC.a2021.0031

Products & Services: Gene Fragments

Hydroxysafflor yellow A inhibits the proliferation, migration, and invasion of colorectal cancer cells through the PPARγ/PTEN/Akt signaling pathway

Authors: Dan Su, Chunye Lv

Journal: Bioengineered

PubMed ID: 34889713

Doi: 10.1080/21655979.2021.2009965

Products & Services: Gene Synthesis

An immunochromatographic assay utilizing magnetic nanoparticles to detect major peanut allergen Ara h 1 in processed foods

Authors: Hsin-Yi Yin, Yi-Ting Li, Wen-Che Tsai, Hong-Yu Dai, Hsiao-Wei Wen

Journal: Food Chem

PubMed ID: 34952385

Doi: 10.1016/j.foodchem.2021.131844

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Critical residues for proteolysis activity of maize chlorotic dwarf virus (MCDV) 3C-like protease and comparison of activity of orthologous waikavirus proteases

Authors: Lucy R Stewart, Matthew Willman, DeeMarie Marty, Anna Emmick Cole, Kristen Willie

Journal: Virology

PubMed ID: 34998226

Doi: 10.1016/j.virol.2021.12.008

Products & Services: Gene Synthesis

Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis

Authors: Yi-Ping Liu, Zhong-Zhi Qiu, Xu-Hui Li, En-You Li

Journal: World J Gastrointest Oncol

PubMed ID: 35070046

Doi: 10.4251/wjgo.v13.i12.2114

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Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma

Authors: Liya Wang, Lucia Unger, Hanan Sharif, Staffan Eriksson, Vinzenz Gerber, Henrik Rönnberg

Journal: BMC Mol Cell Biol

PubMed ID: 34906077

Doi: 10.1186/s12860-021-00399-x

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Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma

Authors: Liya Wang, Lucia Unger, Hanan Sharif, Staffan Eriksson, Vinzenz Gerber, Henrik Rönnberg

Journal: BMC Mol Cell Biol

PubMed ID: 34906077

Doi: 10.1186/s12860-021-00399-x

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Chromosome-specific painting unveils chromosomal fusions and distinct allopolyploid species in the Saccharum complex

Authors: Fan Yu, Xinwang Zhao, Jin Chai, Xueer Ding, Xueting Li, Yongji Huang, Xianhong Wang, Jiayun Wu, Muqing Zhang, Qinghui Yang, Zuhu Deng, Jiming Jiang

Journal: New Phytol

PubMed ID: 34874076

Doi: 10.1111/nph.17905

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Ndufa6 regulates adipogenic differentiation via Scd1

Authors: Jingwei Zhang, Wei Wang, Ninghan Feng, Xuan Jiang, Shenglong Zhu, Yong Q Chen

Journal: Adipocyte

PubMed ID: 34793269

Doi: 10.1080/21623945.2021.2007590

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Circular RNA erythrocyte membrane protein band 41 assuages ultraviolet irradiation-induced apoptosis of lens epithelial cells by stimulating 5'-bisphosphate nucleotidase 1 in a miR-24-3p-dependent manner

Authors: Cuiyun Zhou, Xiaoqiong Huang, Xia Li, Yan Xiong

Journal: Bioengineered

PubMed ID: 34652259

Doi: 10.1080/21655979.2021.1990196

Products & Services: Protein Electrophoresis and Western

Transcription factor specificity protein 1-mediated Serine/threonine kinase 39 upregulation promotes the proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells by activating the transforming growth factor-β1 /Smad2/3 pathway

Authors: Jing Wang, Zhenyu Fan, Jia Li, Jingmao Yang, Xiaofei Liu, Jilin Cheng

Journal: Bioengineered

PubMed ID: 34281492

Doi: 10.1080/21655979.2021.1947939

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Correction to: Expanding the Genetic and Phenotypic Spectrum of Female Infertility Caused by TUBB8 Mutations

Authors: Qianneng Lu, Xiaolan Zhang, Qiqi Cao, Congjing Wang, Jie Ding, Chun Zhao, Junqiang Zhang, Xiufeng Ling, Qingxia Meng, Ran Huo, Hong Li

Journal: Reprod Sci

PubMed ID: 34542892

Doi: 10.1007/s43032-021-00742-9

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Melatonin protects H9c2 cardiomyoblasts from oxygen glucose deprivation and reperfusion-induced injury by inhibiting Rac1/JNK/Foxo3a/Bim signaling pathway

Authors: Yulin Wang, Ying Jian, Xiaofu Zhang, Bin Ni, Mingwei Wang, Chunqi Pan

Journal: Cell Biol Int

PubMed ID: 34882903

Doi: 10.1002/cbin.11739

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Enhancing the detection sensitivity of nanobody against aflatoxin B through structure-guided modification

Authors: Ting He, Yao Nie, Tingting Yan, Jiang Zhu, Xiaoling He, Ying Li, Qi Zhang, Xiaoqian Tang, Rui Hu, Yunhuang Yang, Maili Liu

Journal: Int J Biol Macromol

PubMed ID: 34863829

Doi: 10.1016/j.ijbiomac.2021.11.182

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Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials

Authors: Gang Zeng, Qianhui Wu, Hongxing Pan, Minjie Li, Juan Yang, Lin Wang, Zhiwei Wu, Deyu Jiang, Xiaowei Deng, Kai Chu, Wen Zheng, Lei Wang, Wanying Lu, Bihua Han, Yuliang Zhao, Fengcai Zhu, Hongjie Yu, Weidong Yin

Journal: Lancet Infect Dis

PubMed ID: 34890537

Doi: 10.1016/S1473-3099(21)00681-2

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A new self-attenuated therapeutic influenza vaccine that uses host cell-restricted attenuation by artificial microRNAs

Authors: Ke Wen, Haiyan Wang, Yanping Chen, Huixiao Yang, Zhichao Zheng, Yongyong Yan, Realivazquez Adilene, Mingtao Zeng

Journal: Int J Pharm

PubMed ID: 34883209

Doi: 10.1016/j.ijpharm.2021.121325

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Cloning and functional identification of setaria italica somatic embryogenesis receptor-like kinase1 gene (SiSERK1)

Authors: Guofan Wu, Wenbo Li, Nongfu Tian, Xin Wang, Wangze Wu, Sheng Zheng

Journal: Gene

PubMed ID: 34902513

Doi: 10.1016/j.gene.2021.146119

Products & Services: Protein and Antibody Isolation

Motif-driven protein binder design towards transferrin receptor helical domain

Authors: Dick J Sjöström, Camilla Mohlin, Elena Ambrosetti, Scott J Garforth, Ana I Teixeira, Sinisa Bjelic

Journal: FEBS J

PubMed ID: 34862739

Doi: 10.1111/febs.16311

Products & Services: Protein and Antibody Isolation

Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

Authors: Moustafa T Mabrouk, Kevin Chiem, Edurne Rujas, Wei-Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H Nissly, Victoria S Cavener, Nina R Boyle, Ty A Sornberger, Suresh V Kuchipudi, Joaquin Ortega, Jean-Philippe Julien, Luis Martinez-Sobrido, Jonathan Lovell

Journal: Sci Adv

PubMed ID: 34851667

Doi: 10.1126/sciadv.abj1476

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Antifungal activity and mode of action of synthetic peptides derived from the tick OsDef2 defensin

Authors: Kabuzi R Mbuayama, Helena Taute, Adam A Strӧmstedt, Megan J Bester, Anabella R M Gaspar

Journal: J Pept Sci

PubMed ID: 34866278

Doi: 10.1002/psc.3383

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Barcoded reciprocal hemizygosity analysis via sequencing illuminates the complex genetic basis of yeast thermotolerance

Authors: Melanie B Abrams, Julie N Chuong, Faisal AlZaben, Claire A Dubin, Jeffrey M Skerker, Rachel B Brem

Journal: G3 (Bethesda)

PubMed ID: 34878132

Doi: 10.1093/g3journal/jkab412

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Architecture of the chloroplast PSI-NDH supercomplex in Hordeum vulgare

Authors: Liangliang Shen, Kailu Tang, Wenda Wang, Chen Wang, Hangjun Wu, Zhiyuan Mao, Shaoya An, Shenghai Chang, Tingyun Kuang, Jian-Ren Shen, Guangye Han, Xing Zhang

Journal: Nature

PubMed ID: 34879391

Doi: 10.1038/s41586-021-04277-6

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Rhomboid-like Protein 5 Provided Partial Protection against Homologous Challenge in Forms of Recombinant Protein and DNA Plasmid in Chickens

Authors: Di Tian, Xiaoqian Liu, Xiangrui Li, Lixin Xu, Ruofeng Yan, Xiaokai Song

Journal: Vaccines (Basel)

PubMed ID: 35062693

Doi: 10.3390/vaccines10010032

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Bio inspired growth factor loaded self assembling peptide nano hydrogel for chronic wound healing

Authors: E Santhini, R Parthasarathy, M Shalini, S Dhivya, L Amalorpava Mary, V Vijaya Padma

Journal: Int J Biol Macromol

PubMed ID: 34920072

Doi: 10.1016/j.ijbiomac.2021.12.026

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pH Low Insertion Peptide-Modified Programmed Cell Death-Ligand 1 Potently Suppresses T-Cell Activation Under Acidic Condition

Authors: Ying Sun, Linhan Hu, Peng Yang, Min Zhang, Xinwei Wang, He Xiao, Chunxia Qiao, Jing Wang, Longlong Luo, Jiannan Feng, Yuanqiang Zheng, Yi Wang, Yanchun Shi, Guojiang Chen

Journal: Front Immunol

PubMed ID: 35003115

Doi: 10.3389/fimmu.2021.794226

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Construction, Investigation and Application of TEV Protease Variants with Improved Oxidative Stability

Authors: Enkhtuya Bayar, Yuanyuan Ren, Yinghua Chen, Yafang Hu, Shuncheng Zhang, Xuelian Yu, Jun Fan

Journal: J Microbiol Biotechnol

PubMed ID: 34528919

Doi: 10.4014/jmb.2106.06075

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Induction of Th1 and Th2 in the protection against SARS-CoV-2 through mucosal delivery of an adenovirus vaccine expressing an engineered spike protein

Authors: Nai-Hsiang Chung, Ying-Chin Chen, Shiu-Ju Yang, Yu-Ching Lin, Horng-Yunn Dou, Lily Hui-Ching Wang, Ching-Len Liao, Yen-Hung Chow

Journal: Vaccine

PubMed ID: 34952759

Doi: 10.1016/j.vaccine.2021.12.024

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SARS-CoV-2 recombinant proteins stimulate distinct cellular and humoral immune response profiles in samples from COVID-19 convalescent patients

Authors: Laís Teodoro da Silva, Marina Mazzilli Ortega, Bruna Tiaki Tiyo, Isabelle Freire Tabosa Viana, Tayná Evily de Lima, Tania Regina Tozetto-Mendoza, Luanda Mara da Silva Oliveira, Franciane Mouradian Emidio Teixeira, Roberto Dias Lins, Alexandre de Almeida, Maria Cassia Mendes-Correa, Alberto Jose da Silva Duarte, Telma Miyuki Oshiro

Journal: Clinics (Sao Paulo)

PubMed ID: 34878034

Doi: 10.6061/clinics/2021/e3548

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Porcine Genome-Wide CRISPR Screen Identifies the Golgi Apparatus Complex Protein COG8 as a Pivotal Regulator of Influenza Virus Infection

Authors: Ao Zhou, Wenhua Zhang, Xia Dong, Bin Tang

Journal: CRISPR J

PubMed ID: 34935491

Doi: 10.1089/crispr.2021.0054

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Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion

Authors: Taimoor H Qazi, Jingyu Wu, Victoria G Muir, Shoshana Weintraub, Sarah E Gullbrand, Daeyeon Lee, David Issadore, Jason A Burdick

Journal: Adv Mater

PubMed ID: 34932833

Doi: 10.1002/adma.202109194

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Low-dose cyclooxygenase-2 (COX-2) inhibitor celecoxib plays a protective role in the rat model of neonatal necrotizing enterocolitis

Authors:

Journal: Bioengineered

PubMed ID: 34546832

Doi: 10.1080/21655979.2021.1980646

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Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner

Authors: Khushwant S Bhullar, Fatemeh Ashkar, Jianping Wu

Journal: Food Chem (Oxf)

PubMed ID: 35415678

Doi: 10.1016/j.fochms.2021.100069

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Protection against avian coronavirus conferred by oral vaccination with live bacteria secreting LTB-fused viral proteins

Authors: Avishai Lublin, Chen Katz, Nady Gruzdev, Itamar Yadid, Itai Bloch, Yigal Farnoushi, Luba Simanov, Asaf Berkowitz, Dalia Elyahu, Jacob Pitcovski, Ehud Shahar

Journal: Vaccine

PubMed ID: 34998606

Doi: 10.1016/j.vaccine.2021.12.053

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Microbial synthesis of 4-hydroxybenzoic acid from renewable feedstocks

Authors: Yueyang Chen, Yufen Chen, Lijun Liu, Yang Zhang, Jifeng Yuan

Journal: Food Chem (Oxf)

PubMed ID: 35415641

Doi: 10.1016/j.fochms.2021.100059

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Ultrasound treatment can increase digestibility of myofibrillar protein of pork with modified atmosphere packaging

Authors: Shuai Jiang, Miao Zhang, Hui Liu, Qian Li, Dejiang Xue, Yingqun Nian, Di Zhao, Kai Shan, Chen Dai, Chunbao Li

Journal: Food Chem

PubMed ID: 35030336

Doi: 10.1016/j.foodchem.2021.131811

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4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase

Authors: Emma G Jackson, Giuliano Cutolo, Bo Yang, Nageswari Yarravarapu, Mary W N Burns, Ganka Bineva-Todd, Chloë Roustan, James B Thoden, Halley M Lin-Jones, Toin H van Kuppevelt, Hazel M Holden, Benjamin Schumann, Jennifer J Kohler, Christina M Woo, Matthew R Pratt

Journal: ACS Chem Biol

PubMed ID: 34931806

Doi: 10.1021/acschembio.1c00818

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Overproduction of medicinal ergot alkaloids based on a fungal platform

Authors: Yongpeng Yao, Wei Wang, Wenyu Shi, Rui Yan, Jun Zhang, Guangzheng Wei, Ling Liu, Yongsheng Che, Chunyan An, Shu-Shan Gao

Journal: Metab Eng

PubMed ID: 34902590

Doi: 10.1016/j.ymben.2021.12.002

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Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp

Authors: Carlos Alberto-Silva, Fernanda Calheta Vieira Portaro, Roberto Tadashi Kodama, Halyne Queiroz Pantaleão, Hidetoshi Inagaki, Ken-Ichi Nihei, Katsuhiro Konno

Journal: Toxins (Basel)

PubMed ID: 34941722

Doi: 10.3390/toxins13120885

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A vesicular stomatitis virus-based prime-boost vaccination strategy induces potent and protective neutralizing antibodies against SARS-CoV-2

Authors: Gyoung Nyoun Kim, Jung-Ah Choi, Kunyu Wu, Nasrin Saeedian, Eunji Yang, Hayan Park, Sun-Je Woo, Gippeum Lim, Seong-Gyu Kim, Su-Kyeong Eo, Hoe Won Jeong, Taewoo Kim, Jae-Hyung Chang, Sang Hwan Seo, Na Hyung Kim, Eunsil Choi, Seungho Choo, Sangkyun Lee, Andrew Winterborn, Yue Li, Kate Parham, Justin M Donovan, Brock Fenton, Jimmy D Dikeakos, Gregory A Dekaban, S M Mansour Haeryfar, Ryan M Troyer, Eric J Arts, Stephen D Barr, Manki Song, C Yong Kang

Journal: PLoS Pathog

PubMed ID: 34914812

Doi: 10.1371/journal.ppat.1010092

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HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma

Authors: Benjy Jy Tan, Kenji Sugata, Omnia Reda, Misaki Matsuo, Kyosuke Uchiyama, Paola Miyazato, Vincent Hahaut, Makoto Yamagishi, Kaoru Uchimaru, Yutaka Suzuki, Takamasa Ueno, Hitoshi Suzushima, Hiroo Katsuya, Masahito Tokunaga, Yoshikazu Uchiyama, Hideaki Nakamura, Eisaburo Sueoka, Atae Utsunomiya, Masahiro Ono, Yorifumi Satou

Journal: J Clin Invest

PubMed ID: 34907908

Doi: 10.1172/JCI150472

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Rice stripe virus activates the bZIP17/28 branch of the unfolded protein response signalling pathway to promote viral infection

Authors: Chenyang Li, Tianze Zhang, Yu Liu, Zongdi Li, Yaqin Wang, Shuai Fu, Yi Xu, Tong Zhou, Jianxiang Wu, Xueping Zhou

Journal: Mol Plant Pathol

PubMed ID: 34897936

Doi: 10.1111/mpp.13171

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GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1

Authors: Lucia Balazova, Miroslav Balaz, Carla Horvath, Áron Horváth, Caroline Moser, Zuzana Kovanicova, Adhideb Ghosh, Umesh Ghoshdastider, Vissarion Efthymiou, Elke Kiehlmann, Wenfei Sun, Hua Dong, Lianggong Ding, Ez-Zoubir Amri, Pirjo Nuutila, Kirsi A Virtanen, Tarja Niemi, Barbara Ukropcova, Jozef Ukropec, Pawel Pelczar, Thorsten Lamla, Bradford Hamilton, Heike Neubauer, Christian Wolfrum

Journal: Nat Commun

PubMed ID: 34880217

Doi: 10.1038/s41467-021-27442-x

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RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation

Authors: Fabian Poetz, Joshua Corbo, Yevgen Levdansky, Alexander Spiegelhalter, Doris Lindner, Vera Magg, Svetlana Lebedeva, Jörg Schweiggert, Johanna Schott, Eugene Valkov, Georg Stoecklin

Journal: Nat Commun

PubMed ID: 34887419

Doi: 10.1038/s41467-021-27471-6

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Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

Authors: Yukiko Sato, Kamila R Mustafina, Yishan Luo, Carolina Martini, David Y Thomas, Paul W Wiseman, John W Hanrahan

Journal: Sci Rep

PubMed ID: 34853321

Doi: 10.1038/s41598-021-02420-x

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Expression profile of RNA binding protein in cervical cancer using bioinformatics approach

Authors: Zhiyuan Huang, Fang Li, Qinchuan Li

Journal: Cancer Cell Int

PubMed ID: 34863153

Doi: 10.1186/s12935-021-02319-7

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Soybean miR159 Regulatory Network Involved in Gibberellin-Modulated Resistance to

Authors: Piao Lei, Nawei Qi, Yuan Zhou, Yuanyuan Wang, Xiaofeng Zhu, Yuanhu Xuan, Xiaoyu Liu, Haiyan Fan, Lijie Chen, Yuxi Duan

Journal: Int J Mol Sci

PubMed ID: 34884977

Doi: 10.3390/ijms222313172

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Non-β-blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

Authors: Caroline T Seebauer, Matthew S Graus, Lan Huang, Alex J McCann, Jill Wylie-Sears, Frank R Fontaine, Tara Karnezis, David Zurakowski, Steven J Staffa, Frédéric A Meunier, John B Mulliken, Joyce Bischoff, Mathias Francois

Journal: J Clin Invest

PubMed ID: 34874911

Doi: 10.1172/JCI151109

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Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors

Authors: Tamara Muliaditan, Leena Halim, Lynsey M Whilding, Benjamin Draper, Daniela Y Achkova, Fahima Kausar, Maya Glover, Natasha Bechman, Appitha Arulappu, Jenifer Sanchez, Katie R Flaherty, Jana Obajdin, Kristiana Grigoriadis, Pierre Antoine, Daniel Larcombe-Young, Caroline M Hull, Richard Buus, Peter Gordon, Anita Grigoriadis, David M Davies, Anna Schurich, John Maher

Journal: Cell Rep Med

PubMed ID: 35028604

Doi: 10.1016/j.xcrm.2021.100457

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Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model

Authors: Murad Alahdal, Rongxiang Huang, Li Duan, Deng Zhiqin, Ouyang Hongwei, Wencui Li, Daping Wang

Journal: Front Immunol

PubMed ID: 34956209

Doi: 10.3389/fimmu.2021.781185

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SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells

Authors: Jinliang Wang, Guan Yang, Xinxin Wang, Zhiyuan Wen, Lei Shuai, Jie Luo, Chong Wang, Ziruo Sun, Renqiang Liu, Jinying Ge, Xijun He, Ronghong Hua, Xijun Wang, Xiao Yang, Weiye Chen, Gongxun Zhong, Zhigao Bu

Journal: Cell Discov

PubMed ID: 34903715

Doi: 10.1038/s41421-021-00357-z

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SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice NF-ĸB Activation

Authors: Jie Xia, Wenqi Tang, Jiangmei Wang, Dengming Lai, Qi Xu, Ruoqiong Huang, Yaoqin Hu, Xiaojue Gong, Jiajie Fan, Qiang Shu, Jianguo Xu

Journal: Front Immunol

PubMed ID: 34950152

Doi: 10.3389/fimmu.2021.791753

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SARS-CoV-2 seroprevalence, seroconversion and neutralizing antibodies in a systemic lupus erythematosus cohort and comparison to controls

Authors: Hannah R Mathew, May Y Choi, Katherine Buhler, Xenia Gukova, Francesca S Cardwell, Heather Waldhauser, Ann E Clarke, Marvin J Fritzler

Journal: Lupus

PubMed ID: 34874781

Doi: 10.1177/09612033211063793

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Engineering a Pseudo-26-kDa Glutathione Transferase from / for Structure, Kinetics, and Ligandin Studies

Authors: Neo Padi, Blessing Oluebube Akumadu, Olga Faerch, Chinyere Aloke, Vanessa Meyer, Ikechukwu Achilonu

Journal: Biomolecules

PubMed ID: 34944488

Doi: 10.3390/biom11121844

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Novel pentose-regulated promoter of with application in controlling heterologous gene expression

Authors: Sukanya Jeennor, Jutamas Anantayanon, Chanikul Chutrakul, Sarocha Panchanawaporn, Kobkul Laoteng

Journal: Biotechnol Rep (Amst)

PubMed ID: 35004236

Doi: 10.1016/j.btre.2021.e00695

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Bak and Bcl-xL Participate in Regulating Sensitivity of Solid Tumor Derived Cell Lines to Mcl-1 Inhibitors

Authors: Viacheslav V Senichkin, Nikolay V Pervushin, Alexey V Zamaraev, Elena V Sazonova, Anton P Zuev, Alena Y Streletskaia, Tatiana A Prikazchikova, Timofei S Zatsepin, Olga V Kovaleva, Elena M Tchevkina, Boris Zhivotovsky, Gelina S Kopeina

Journal: Cancers (Basel)

PubMed ID: 35008345

Doi: 10.3390/cancers14010181

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Comparison of SARS-CoV-2 Antibody Response 4 Weeks After Homologous vs Heterologous Third Vaccine Dose in Kidney Transplant Recipients: A Randomized Clinical Trial

Authors: Roman Reindl-Schwaighofer, Andreas Heinzel, Manuel Mayrdorfer, Rhea Jabbour, Thomas M Hofbauer, Anne Merrelaar, Michael Eder, Florina Regele, Konstantin Doberer, Paul Spechtl, Constantin Aschauer, Maximilian Koblischke, Christopher Paschen, Farsad Eskandary, Karin Hu, Barbara Öhler, Arshdeep Bhandal, Sabine Kleibenböck, Rahel I Jagoditsch, Bianca Reiskopf, Florian Heger, Gregor Bond, Georg A Böhmig, Robert Strassl, Lukas Weseslindtner, Alexander Indra, Judith H Aberle, Michael Binder, Rainer Oberbauer

Journal: JAMA Intern Med

PubMed ID: 34928302

Doi: 10.1001/jamainternmed.2021.7372

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Development of competitive and noncompetitive immunoassays for clothianidin with high sensitivity and specificity using phage-displayed peptides

Authors: Tianyang You, Yuan Ding, He Chen, Guangyue Song, Lianrun Huang, Minghua Wang, Xiude Hua

Journal: J Hazard Mater

PubMed ID: 34896720

Doi: 10.1016/j.jhazmat.2021.128011

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A New Testing Platform Using Fingerstick Blood for Quantitative Antibody Response Evaluation after SARS-CoV-2 Vaccination

Authors: Jinwei Du, Dayu Zhang, Joseph A Pathakamuri, Daniel Kuebler, Ying Yang, Yulia Loginova, Eric Chu, Roberta Madej, Jocelyn V Neves, Brianna Singer, Holly Radke, Naomi Spencer, Elizabeth Rizk, Aiguo Zhang, Chuanyi M Lu, Michael Y Sha

Journal: Emerg Microbes Infect

PubMed ID: 34951566

Doi: 10.1080/22221751.2021.2023328

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Rapid directed molecular evolution of fluorescent proteins in mammalian cells

Authors: Siranush Babakhanova, Erica E Jung, Kazuhiko Namikawa, Hanbin Zhang, Yangdong Wang, Oksana M Subach, Dmitry A Korzhenevskiy, Tatiana V Rakitina, Xian Xiao, Wenjing Wang, Jing Shi, Mikhail Drobizhev, Demian Park, Lea Eisenhard, Hongyun Tang, Reinhard W Köster, Fedor V Subach, Edward S Boyden, Kiryl D Piatkevich

Journal: Protein Sci

PubMed ID: 34913537

Doi: 10.1002/pro.4261

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