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Cholesterol analogs modulate lipid nanoparticle performance for mRNA delivery after lyophilization and enable ocular disease therapy

Authors: Ting Wang, Wanqi Li, Jianyang Chen, Sitian Cheng, Min Gao, Chengyu Jiang, Chengyu Jiang, Bingyi Hu, Tzu-Cheng Sung, Akon Higuchi

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.103044

Products & Services: Custom mRNA synthesis

NIR-II Biomimetic Nanoplatform Optogenetic CD274 Editing of HNSCC Immunogenicity for Enhanced Photoimmunotherapy

Authors: Yang Chen, Longcai Liu, Xiaojuan Hu, Yilin Huang, Shijie Yao, Lichen Ji, Hai Zou, Xiaozhou Mou, Yu Cai

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.102803

Products & Services: Synthetic Guide RNA CRISPR Plasmids

Palmitic acid reprograms neutrophils to compromise vascular integrity and promote breast cancer lung metastasis

Authors: Peng Qian, Yuxin Li, Yifeng Han, Chun Xu, Peng Zou, Fuming Yang, Xiaozhen Kang, Mengdi Wu, Jie Dong, Zhengyun Zou, Jiwu Wei

Journal: Immunity

PubMed ID: 42034064

Doi: 10.1016/j.immuni.2026.03.026

Products & Services: Recombinant Proteins Lentivirus Packaging Protein Electrophoresis and Western

PEX11 mediates intralumenal vesicle formation in peroxisomes

Authors: Nathan E Tharp, Chelsea An, James Hwang, Nayeli S Shad, Zachary J Wright, Bonnie Bartel

Journal: Nature Communications

PubMed ID: 42014717

Doi: 10.1038/s41467-026-71873-3

Products & Services: Custom Vector Construction Protein Electrophoresis and Western

Quadruple pegRNA enables programmable and efficient large genomic insertion

Authors: Ya-Jing Shi, Zi-Yi Ding, Ying Wu, Zhou He, Yi-Zhou Zhang, Yu-Lu Zhang, Yu-Ming Zhang, Xiang-Rui Huang, Hao Yin, Ying Zhang

Journal: Nature

PubMed ID: 42020736

Doi: 10.1038/s41586-026-10395-w

Products & Services: Cell Isolation

Multi-level Integrated Engineering Enhances Neutral β-Glucanase Production in Komagataella phaffii

Authors: Hai Xu, Xiaowei Shao, Yuzhe Peng, Xiuxia Liu, Chunli Liu, Zhonghu Bai, Yankun Yang

Journal: Journal of biotechnology

PubMed ID: 41999774

Doi: 10.1016/j.jbiotec

Harnessing Microbial Bioremediation and Wastewater Valorization for Production of (Methyl)muconates via Engineered Metabolic Pathways in Aromatic Pollutant Mixtures

Authors: Siqing Fan, Xueni Fu, Xiaoyu Wang, Lvjing Wang, Hongyu Chen, Christopher E French, Hongzhi Tang, Hao Ren, Zhenmei Lu

Journal: Environmental science & technology

PubMed ID: 42049681

Doi: 10.1021/acs.est.5c11064

Products & Services: Gene Synthesis

Revisiting the antizyme 1 - ODC interaction reveals low-nanomolar affinity

Authors: Grzegorz P Bereta, Elżbieta Wątor-Wilk, Paweł Kochanowski, Jakub Nowak, Tomasz Kantyka, Przemysław Grudnik

Journal: Amino Acids

PubMed ID: 41989609

Doi: 10.1007/s00726-026-03519-z

Products & Services: PCR Cloning and Subcloning

Structural and functional dissection of a higherorder oligomerization interface in yeast ceramide synthase

Authors: Qi Fang, Chang Yang, Nan Yao, Tian Xie, Xin Gong

Journal: Nature Communications

PubMed ID: 41917020

Doi: doi.org/10.1038/s41467-026-71272-8

Products & Services: Protein and Antibody Isolation

The COP1-ADA2b module mediates light regulation of DNA double-strand break repair in Arabidopsis

Authors: Li Chen, Liman Diao, Jiaqi Ruan, Yanli Deng, Kai Zhang, Yan Guan, Ling Li, Min Liang, Lina Peng, Jiayi Shi, Shilong Zhang, Minqing Liu, Yupeng Li, Zhilei Mao, Wenxiu Wang, Hong-Quan Yang, Tongtong Guo

Journal: Nature Communications

PubMed ID: 41820379

Doi: 10.1038/s41467-026-70673-z

Products & Services: Catalog Antibodies