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The BEL1-like homeodomain protein OsBLH4 regulates rice plant height, grain number, and heading date by repressing the expression of OsGA2ox1

Authors: Chengjuan Cao, Shuaiqiang Guo, Ping Deng, Shiyi Yang, Jing Xu, Tengfei Hu, Zhijuan Hu, Di Chen, Hongsheng Zhang, Ian Paul Navea, Joong Hyoun Chin, Wenhua Zhang, Wen Jing

Journal: Plant J

PubMed ID: 38824648

Doi: 10.1111/tpj.16857

Products & Services: Molecular Biology Reagents

Ectoine enhances recombinant antibody production in Chinese hamster ovary cells by promoting cell cycle arrest

Authors: Salinthip Jarusintanakorn, Enrico Mastrobattista, Montarop Yamabhai

Journal: N Biotechnol

PubMed ID: 38945523

Doi: 10.1016/j.nbt.2024.06.006

Products & Services: Recombinant Proteins

CD147-K148me2-Driven Tumor Cell-Macrophage Crosstalk Provokes NSCLC Immunosuppression via the CCL5/CCR5 Axis

Authors: Ke Wang, Xiaohong Chen, Peng Lin, Jiao Wu, Qiang Huang, Zhi-Nan Chen, Jiale Tian, Hao Wang, Ye Tian, Mingyan Shi, Meirui Qian, Bengang Hui, Yumeng Zhu, Ling Li, Rui Yao, Huijie Bian, Ping Zhu, Ruo Chen, Liang Chen

Journal: Adv Sci (Weinh)

PubMed ID: 38873823

Doi: 10.1002/advs.202400611

Products & Services: Recombinant Proteins

Functional diversity among cardiolipin binding sites on the mitochondrial ADP/ATP carrier

Authors: Nanami Senoo, Dinesh K Chinthapalli, Matthew G Baile, Vinaya K Golla, Bodhisattwa Saha, Abraham O Oluwole, Oluwaseun B Ogunbona, James A Saba, Teona Munteanu, Yllka Valdez, Kevin Whited, Macie S Sheridan, Dror Chorev, Nathan N Alder, Eric R May, Carol V Robinson, Steven M Claypool

Journal: EMBO J

PubMed ID: 38839991

Doi: 10.1038/s44318-024-00132-2

Products & Services: Proteins, Expression, Isolation and Analysis

Elucidating the role of primary and secondary sphere Zn ligands in the cyanobacterial CO uptake complex NDH-1: The essentiality of arginine in zinc coordination and catalysis

Authors: Ross M Walker, Minquan Zhang, Robert L Burnap

Journal: Biochim Biophys Acta Bioenerg

PubMed ID: 38906312

Doi: 10.1016/j.bbabio.2024.149149

Products & Services: Mutant Libraries

Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast

Authors: Yuanwei Gou, Dongfang Li, Minghui Zhao, Mengxin Li, Jiaojiao Zhang, Yilian Zhou, Feng Xiao, Gaofei Liu, Haote Ding, Chenfan Sun, Cuifang Ye, Chang Dong, Jucan Gao, Di Gao, Zehua Bao, Lei Huang, Zhinan Xu, Jiazhang Lian

Journal: Nat Commun

PubMed ID: 38898098

Doi: 10.1038/s41467-024-49554-w

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Recovery kinetics of dual AAV-mediated human otoferlin expression

Authors: Jonathan B Sellon, Kathy S So, Andrew D'Arcangelo, Sarah Cancelarich, Meghan C Drummond, Peter G Slade, Ning Pan, Tyler M Gibson, Tian Yang, Joseph C Burns, Adam T Palermo, Lars Becker

Journal: Front Mol Neurosci

PubMed ID: 38952419

Doi: 10.3389/fnmol.2024.1376128

Products & Services: Gene Synthesis

Boosting PRRSV-Specific Cellular Immunity: The Immunological Profiling of an Fc-Fused Multi-CTL Epitope Vaccine in Mice

Authors: Xinnuo Lei, Jinzhao Ban, Zhi Wu, Shinuo Cao, Mo Zhou, Li Zhang, Rui Zhu, Huipeng Lu, Shanyuan Zhu

Journal: Vet Sci

PubMed ID: 38922021

Doi: 10.3390/vetsci11060274

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Identification of core techniques that enhance genome editing of human T cells expressing synthetic antigen receptors

Authors: Ju-Fang Chang, Nils Wellhausen, Nils Wolfgang Engel, Jack H Landmann, Caitlin R Hopkins, January Salas-McKee, Adham S Bear, Mehmet Emrah Selli, Sangya Agarwal, Julie Jadlowsky, Gerald P Linette, Saar Gill, Carl H June, Joseph A Fraietta, Nathan Singh

Journal: Cancer Immunol Res

PubMed ID: 38869428

Doi: 10.1158/2326-6066.CIR-24-0251

Products & Services: Molecular Biology Reagents

Astragaloside IV inhibits cell viability and glycolysis of hepatocellular carcinoma by regulating KAT2A-mediated succinylation of PGAM1

Authors: Yuanzhang Zhu, Fei Lu

Journal: BMC Cancer

PubMed ID: 38835015

Doi: 10.1186/s12885-024-12438-9

Products & Services: Molecular Biology Reagents

One-shot design elevates functional expression levels of a voltage-gated potassium channel

Authors: Jonathan Jacob Weinstein, Chandamita Saikia, Izhar Karbat, Adi Goldenzweig, Eitan Reuveny, Sarel Jacob Fleishman

Journal: Protein Sci

PubMed ID: 38747377

Doi: 10.1002/pro.4995

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DNA-controlled protein fluorescence: Design of aptamer-split peptide hetero-modulator for GFP to respond to intracellular ATP levels

Authors: Ki Sung Park, Hanvit Cha, Jia Niu, Hyongsok Tom Soh, Jin Hyup Lee, Seung Pil Pack

Journal: Nucleic Acids Res

PubMed ID: 38917331

Doi: 10.1093/nar/gkae532

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Exploring solute binding proteins in Pseudomonas aeruginosa that bind to γ-aminobutyrate and 5-aminovalerate and their role in activating sensor kinases

Authors: Jean Paul Cerna-Vargas, Tino Krell

Journal: Microbiologyopen

PubMed ID: 38780167

Doi: 10.1002/mbo3.1415

Products & Services: Gene Synthesis

A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism

Authors: Shin-Ichiro Takayanagi, Sayaka Chuganji, Masahiro Tanaka, Bo Wang, Saki Hasegawa, Ken Fukumoto, Nariaki Wasano, Makoto Kakitani, Nakaba Ochiai, Yohei Kawai, Tatsuki Ueda, Akihiro Ishikawa, Yuko Kurimoto, Asami Fukui, Sanae Kamibayashi, Eri Imai, Atsushi Kunisato, Hajime Nozawa, Shin Kaneko

Journal: Commun Biol

PubMed ID: 38834758

Doi: 10.1038/s42003-024-06297-0

Products & Services: Proteins, Expression, Isolation and Analysis

Capturing totipotency in human cells through spliceosomal repression

Authors: Shiyu Li, Min Yang, Hui Shen, Li Ding, Xuehui Lyu, Kexin Lin, Jennie Ong, Peng Du

Journal: Cell

PubMed ID: 38843832

Doi: 10.1016/j.cell.2024.05.010

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NpeA is a secreted Type IV effector containing an N-WASP-binding short linear motif that promotes niche formation

Authors: Agostina Giménez, Mariela G Del Giudice, Paula V López, Francisco Guaimas, Hugo Sámano-Sánchez, Toby J Gibson, Lucía B Chemes, Carlos O Arregui, Juan E Ugalde, Cecilia Czibener

Journal: MBio

PubMed ID: 38847540

Doi: 10.1128/mbio.00726-24

Products & Services: Gene Synthesis

XIST dampens X chromosome activity in a SPEN-dependent manner during early human development

Authors: Charbel Alfeghaly, Gaël Castel, Emmanuel Cazottes, Madeleine Moscatelli, Eva Moinard, Miguel Casanova, Juliette Boni, Kasturi Mahadik, Jenna Lammers, Thomas Freour, Louis Chauviere, Carla Piqueras, Ruben Boers, Joachim Boers, Joost Gribnau, Laurent David, Jean-François Ouimette & Claire Rougeulle

Journal: Nat Struct Mol Biol

PubMed ID: 38834912

Doi: 10.1038/s41594-024-01325-3

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Characterization and regulation of cell cycle-independent noncanonical gene targeting

Authors: Shinta Saito & Noritaka Adachi

Journal: Nature Communications

PubMed ID: 38890315

Doi: 10.1038/s41467-024-49385-9.

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A safe and potentiated multi-type HPV L2-E7 nanoparticle vaccine with combined prophylactic and therapeutic activity

Authors: Xueer Zhao, Yueru Zhang, Oscar Trejo-Cerro, Ecem Kaplan, Zhe Li, Femke Albertsboer, Neyla El Hammiri, Filipe Colaço Mariz, Lawrence Banks, Simone Ottonello, Martin Müller

Journal: npj Vaccines

PubMed ID: 38926425

Doi: 10.1038/s41541-024-00914-z

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Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex

Authors: Qiyin An, Yong Wang, Zhenhua Tian, Jie Han, Jinyue Li, Fumeng Liao, Feiyang Yu, Haiyan Zhao, Yancheng Wen, Heng Zhang & Zengqin Deng

Journal: Cell Research

PubMed ID: 38834762

Doi: 10.1038/s41422-024-00981-w

Products & Services: Proteins, Expression, Isolation and Analysis

Estrogen-mediated DNMT1 and DNMT3A recruitment by EZH2 silences miR-570-3p that contributes to papillary thyroid malignancy through DPP4

Authors: Xiarong Hu, Qingyao Ye, HuanQuan Lu, Zhiming Wu, Siyuan Chen, Ruinian Zheng

Journal: Clin Epigenetics

PubMed ID: 38890707

Doi: 10.1186/s13148-024-01685-z

Products & Services: Proteins, Expression, Isolation and Analysis

Enhanced Recombinant Protein Expression in Insect Cells by Natural and Recombinant Components of Lepidoptera Hemolymph

Authors: Javier López-Vidal, Susana Martínez-Pulgarín, Diego Martínez-Alonso, Miguel Cid, José M Escribano

Journal: Viruses

PubMed ID: 38932236

Doi: 10.3390/v16060944

Products & Services: Proteins, Expression, Isolation and Analysis

A quadrivalent recombinant influenza Hemagglutinin vaccine induced strong protective immune responses in animal models

Authors: Jin Feng, Yingying Du, Liyun Chen, Wenhan Su, Hailiu Wei, Aijiao Liu, Xiaojun Jiang, Jianmin Guo, Cailing Dai, Yuhua Xu, Tao Peng

Journal: Vaccine

PubMed ID: 38834431

Doi: 10.1016/j.vaccine.2024.05.056

Products & Services: Proteins, Expression, Isolation and Analysis Peptide Library Services

CEPs suppress auxin signaling but promote cytokinin signaling to inhibit root growth in Arabidopsis

Authors: Yuwen Zhang, Xingliang Duan, Zhen Wang, Yuanda Lv, Weicong Qi, Lun Li, Le Luo, Wei Xuan

Journal: Biochem Biophys Res Commun .

PubMed ID: 38626621

Doi: 10.1016/j.bbrc.2024.149934

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Next-generation nanovaccine induces durable immunity and protects against SARS-CoV-2

Authors: Kathleen A Ross, Sean Kelly, Kruttika S Phadke, Nathan Peroutka-Bigus, Olufemi Fasina, Alaric Siddoway, Surya K Mallapragada, Michael J Wannemuehler, Bryan H Bellaire, Balaji Narasimhan

Journal: Acta Biomater

PubMed ID: 38844193

Doi: 10.1016/j.actbio.2024.05.048

Products & Services: Molecular Biology Reagents

Identification of potential crucial cuproptosis-related genes in myocardial ischemia-reperfusion injury through the bioinformatic analysis

Authors: Rong Huang, Rongfeng Xu, Rui Zhang, Wenjie Zuo, Zhenjun Ji, Zaixiao Tao, Yongjun Li, Genshan Ma

Journal: Clinics (Sao Paulo)

PubMed ID: 38901133

Doi: 10.1016/j.clinsp.2024.100410

Products & Services: Gene Synthesis

Transcriptional genes of lysosome-associated membrane protein 2A in sciatic nerve injuries by bioinformatics

Authors: Eun Jung Sohn, Kun-Taek Park

Journal: Neuroreport

PubMed ID: 38935077

Doi: 10.1097/WNR.0000000000002066

Products & Services: Gene Synthesis

High sugar diet-induced fatty acid oxidation potentiates cytokine-dependent cardiac ECM remodeling

Authors: Jayati Gera, Dheeraj Kumar, Gunjan Chauhan, Adarsh Choudhary, Lavi Rani, Lolitika Mandal, Sudip Mandal

Journal: J Cell Biol

PubMed ID: 38916917

Doi: 10.1083/jcb.202306087

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Hepatitis C virus NS5A and core protein induce fibrosis-related genes regulation on Huh7 cells through activation of LX2 cells

Authors: Tania G Heredia-Torres, Veronica Alvarado-Martínez, Ana R Rincon-Sanchez, Sonia A Lozano-Sepulveda, Kame Galan-Huerta, Daniel Arellanos-Soto, Ana M Rivas-Estilla

Journal: Ann Hepatol

PubMed ID: 38852781

Doi: 10.1016/j.aohep.2024.101517

Products & Services: Molecular Biology Reagents

Sequence and structure analyses of lytic polysaccharide monooxygenases mined from metagenomic DNA of humus samples around white-rot fungi in Cuc Phuong tropical forest, Vietnam

Authors: Nam-Hai Truong, Thi-Thu-Hong Le, Hong-Duong Nguyen, Hong-Thanh Nguyen, Trong-Khoa Dao, Thi-Minh-Nguyet Tran, Huyen-Linh Tran, Dinh-Trong Nguyen, Thi-Quy Nguyen, Thi-Hong-Thao Phan, Thi-Huyen Do, Ngoc-Han Phan, Thi-Cam-Nhung Ngo, Van-Van Vu

Journal: PeerJ

PubMed ID: 38938609

Doi: 10.7717/peerj.17553

Products & Services: Molecular Biology Reagents

nCas9 Engineering for Improved Target Interaction Presents an Effective Strategy to Enhance Base Editing

Authors: Guiquan Zhang, Ziguo Song, Shisheng Huang, Yafeng Wang, Jiayuan Sun, Lu Qiao, Guanglei Li, Yuanyuan Feng, Wei Han, Jin Tang, Yulin Chen, Xingxu Huang, Furui Liu, Xiaolong Wang, Jianghuai Liu

Journal: Adv Sci (Weinh)

PubMed ID: 38881503

Doi: 10.1002/advs.202405426

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Improvement of TaC9-ABE mediated correction of human SMN2 gene

Authors: Xiaohua Peng, Yue Chi, Jinling Wang, Shuangpeng Li, Yang Liu, Chengcheng Tang, Xiaoqing Zhou, Xuan Lu, Yue Gao, Liangxue Lai, Min Chen, Qingjian Zou

Journal: Biotechnol Bioeng

PubMed ID: 38923503

Doi: 10.1002/bit.28780

Products & Services: GenCrispr Cas9 Genome Editing

Structural basis for hormone recognition and distinctive Gq protein coupling by the kisspeptin receptor

Authors: Shiyi Shen, Dongxue Wang, Heng Liu, Xinheng He, Yinglong Cao, Juanhua Chen, Shujie Li, Xi Cheng, H Eric Xu, Jia Duan

Journal: Cell Rep

PubMed ID: 38935498

Doi: 10.1016/j.celrep.2024.114389

Products & Services: Recombinant Proteins

Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design

Authors: Manjeet Mukherjee, Philip J Day, Duncan Laverty, Juan A Bueren-Calabuig, Andrew J Woodhead, Charlotte Griffiths-Jones, Steve Hiscock, Charlotte East, Susan Boyd, Marc O'Reilly

Journal: Structure

PubMed ID: 38870939

Doi: 10.1016/j.str.2024.05.011

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The BICD2 dynein cargo adaptor binds to the HPV16 L2 capsid protein and promotes HPV infection

Authors: Kaitlyn Speckhart, Jeongjoon Choi, Daniel DiMaio, Billy Tsai

Journal: PLoS Pathog

PubMed ID: 38829892

Doi: 10.1371/journal.ppat.1012289

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The role of shear forces in primary and secondary nucleation of amyloid fibrils

Authors: Emil Axell, Jing Hu, Max Lindberg, Alexander J Dear, Lei Ortigosa-Pascual, Ewa A Andrzejewska, Greta Šneiderienė, Dev Thacker, Tuomas P J Knowles, Emma Sparr, Sara Linse

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38875148

Doi: 10.1073/pnas.2322572121

Products & Services: Molecular Biology Reagents

Dual-Omics Approach Unveils Novel Perspective on the Quality Control of Genetically Engineered Exosomes

Authors: Christopher Olson, Konstantin Ivanov, Darin Boyes, David Bengford, Joy Ku, Renceh Flojo, Pengyang Zhang, Biao Lu

Journal: Pharmaceutics

PubMed ID: 38931944

Doi: 10.3390/pharmaceutics16060824

Products & Services: Molecular Biology Reagents

The generation of stable transgenic lines in the human-infective nematode Strongyloides stercoralis

Authors: Ruhi Patel, Astra S Bryant, Michelle L Castelletto, Breanna Walsh, Damia Akimori, Elissa A Hallem

Journal: G3 (Bethesda)

PubMed ID: 38839055

Doi: 10.1093/g3journal/jkae122

Products & Services: Molecular Biology Reagents

The annotation of has been concealed by its protein-coding pseudogene

Authors: Emil K Gustavsson, Siddharth Sethi, Yujing Gao, Jonathan W Brenton, Sonia García-Ruiz, David Zhang, Raquel Garza, Regina H Reynolds, James R Evans, Zhongbo Chen, Melissa Grant-Peters, Hannah Macpherson, Kylie Montgomery, Rhys Dore, Anna I Wernick, Charles Arber, Selina Wray, Sonia Gandhi, Julian Esselborn, Cornelis Blauwendraat, Christopher H Douse, Anita Adami, Diahann A M Atacho, Antonina Kouli, Annelies Quaegebeur, Roger A Barker, Elisabet Englund, Frances Platt, Johan Jakobsson, Nicholas W Wood, Henry Houlden, Harpreet Saini, Carla F Bento, John Hardy, Mina Ryten

Journal: Sci Adv

PubMed ID: 38924406

Doi: 10.1126/sciadv.adk1296

Products & Services: Proteins, Expression, Isolation and Analysis

Arabidopsis pollen prolyl-hydroxylases P4H4/6 are relevant for correct hydroxylation and secretion of LRX11 in pollen tubes

Authors: Ana R Sede, Diego L Wengier, Cecilia Borassi, Martiniano Ricardi, Sofía C Somoza, Rafael Aguiló, José M Estevez, Jorge P Muschietti

Journal: J Exp Bot

PubMed ID: 38877792

Doi: 10.1093/jxb/erae269

Products & Services: Proteins, Expression, Isolation and Analysis

Ancient nitrogenases are ATP dependent

Authors: Derek F Harris, Holly R Rucker, Amanda K Garcia, Zhi-Yong Yang, Scott D Chang, Hannah Feinsilber, Betül Kaçar, Lance C Seefeldt

Journal: MBio

PubMed ID: 38869277

Doi: 10.1128/mbio.01271-24

Products & Services: Proteins, Expression, Isolation and Analysis

MiR-23b-3p alleviates Sjögren's syndrome by targeting SOX6 and inhibiting the NF-κB signaling

Authors: Yan Cai, Yi Zhang, Sihan Wang, E Changyong

Journal: Mol Immunol

PubMed ID: 38901181

Doi: 10.1016/j.molimm.2024.06.002

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PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2

Authors: Noah Giacon, Ettore Lo Cascio, Valeria Pennacchietti, Flavio De Maio, Giulia Santarelli, Diego Sibilia, Federica Tiberio, Maurizio Sanguinetti, Wanda Lattanzi, Angelo Toto, Alessandro Arcovito

Journal: Sci Rep

PubMed ID: 38844490

Doi: 10.1038/s41598-024-63239-w

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Inefficient recruitment of DDX39B impedes pre-spliceosome assembly on introns

Authors: Chloe K Nagasawa, Aaron O Bailey, William K Russell, Mariano A Garcia-Blanco

Journal: RNA

PubMed ID: 38575347

Doi: 10.1261/rna.079933.123

Products & Services: Proteins, Expression, Isolation and Analysis

Discovery of Monovalent Direct Degraders of BRD4 That Act Via the Recruitment of DCAF11

Authors: Gregory S Parker, Julia I Toth, Sarah Fish, Gabrielle A Blanco, Taylor Kampert, Xiaoming Li, Linette Yang, Craig R Stumpf, Kenneth Steadman, Aleksandar Jamborcic, Stephen Chien, Elizabeth Daniele, Alejandro Dearie, Geoffray Leriche, Simon Bailey, Peggy A Thompson

Journal: Mol Cancer Ther

PubMed ID: 38907538

Doi: 10.1158/1535-7163.MCT-24-0219

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular Mechanism of WWOX Inhibiting the Development of Esophageal Cancer by Inhibiting Hippo Signaling Pathway

Authors: Zihan Chen, Jingyu Sun, Lili Zhang, Yanglin Sun, Qingqing Ni, Hongkun Zhu, Miao Hui, Longzhen Zhang, Qiang Wang

Journal: Biochem Genet

PubMed ID: 38902482

Doi: 10.1007/s10528-024-10856-9

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Integration of Image Pattern Recognition and Photon Sensor for Analyzing Cytokine Gene Expression Using πCode MicroDisc

Authors: On-Anong Juntit, Kanokporn Sornsuwan, Umpa Yasamut, Chatchai Tayapiwatana

Journal: Biosensors (Basel)

PubMed ID: 38920610

Doi: 10.3390/bios14060306

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T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector

Authors: Ingrid Fert, Laëtitia Douguet, Benjamin Vesin, Fanny Moncoq, Amandine Noirat, Pierre Authié, Sylvain Ciret, Fabien Le Chevalier, Catherine Blanc, Yakov Vitrenko, Pierre Charneau, Laleh Majlessi, François Anna

Journal: npj Vaccines

PubMed ID: 38858404

Doi: 10.1038/s41541-024-00894-0

Products & Services: Proteins, Expression, Isolation and Analysis

Evaluation of transmission-blocking potential of PvPSOP25 using transgenic murine malaria parasite and clinical isolates

Authors: Biying Zhang, Hao Feng, Yan Zhao, Di Zhang, Xinxin Yu, Yusi Li, Ying Zeng, Sataporn Thongpoon, Wanlapa Roobsoong, Yudi Wu, Fei Liu, Jetsumon Sattabongkot, Hui Min, Liwang Cui, Yaming Cao

Journal: PLoS Negl Trop Dis

PubMed ID: 38865344

Doi: 10.1371/journal.pntd.0012231

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Comparison of the performance of SAG2, GRA6, and GRA7 for serological diagnosis of infection in cats

Authors: Serges Sabukunze, Haorong Gu, Lin Zhao, Honglin Jia, Huanping Guo

Journal: Front Vet Sci

PubMed ID: 38898997

Doi: 10.3389/fvets.2024.1423581

Products & Services: Proteins, Expression, Isolation and Analysis

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