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Generation of antigen-specific paired-chain antibodies using large language models

Authors: Perry T Wasdin, Nicole V Johnson, Alexis K Janke, Sofia Held, Toma M Marinov, Gwen Jordaan, Rebecca A Gillespie, Léna Vandenabeele, Fani Pantouli, Olivia C Powers, Matthew J Vukovich, Clinton M Holt, Jeongryeol Kim, Grant Hansman, Jennifer Logue, Helen Y Chu, Sarah F Andrews, Masaru Kanekiyo, Giuseppe A Sautto, Ted M Ross, Daniel J Sheward, Jason S McLellan, Alexandra A Abu-Shmais, Ivelin S Georgiev

Journal: Cell

PubMed ID: 41192421

Doi: 10.1016/j.cell.2025.10.006.

Products & Services: Protein and Antibody Isolation

On-target off-tumor toxicity of claudin18.2-directed CAR-T cells in preclinical models

Authors: Filippo Birocchi, Antonio J Almazan, Aiyana Parker, Amanda A Bouffard, Sadie Goncalves, Christopher Kelly, Jessica Frank, Mark B Leick, Nicholas J Haradhvala, Shaw Kagawa, Gad Getz, Giulia Escobar, Diego Salas-Benito, Adele Mucci, Trisha R Berger, Marcela V Maus

Journal: Nature Communications

PubMed ID: 41176533

Doi: 10.1038/s41467-025-61858-z.

Products & Services: Monoclonal Antibody Services

Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence

Authors: Melinda Soeung, Xinmiao Yan, Ciro Zanca, Jing Qian, Menuka Karki, Fei Duan, Hania Khan, Li Zhang, David H Peng, Mariah Williams, Rong He, Ziheng Chen, Luigi Perelli, Jianfeng Chen, Rebecca S Tidwell, Pankaj K Chauhan, Courtney N Le, Truong N A Lam, Nirjar Bhattacharya, Rutvi Shah, I-Lin Ho, Jason P Gay, Caroline C Carrillo, Ningping Feng, Kang Le, Guang Gao, Teresa L Perry, Faika Mseeh, Yongying Jiang, Quanyun A Xu, Niki Marie Zacharias, Rahul A Sheth, Tharakeswara K Bathala, Priya Rao, Najat C Daw, Durga N Tripathi, Cheryl L Walker, Mohammad M Mohammad, Jianhua Zhang, Guangchun Han, Yanshuo Chu, Ruiping Wang, Minghao Dang, Enyu Dai, Fuduan Peng, Yunhe Liu, Akshaya Jadhav, Wenhua Lang, Claudio A Arrechedera, Leticia Campos Clemente, Edwin R Parra, Hsinyi Lu, Cara L Haymaker, Ignacio I Wistuba, Andrew Futreal, Andrea Viale, Michael J Soth, Philip Jones, Joseph R Marszalek, Timothy Heffernan, Giulio F Draetta, Nizar M Tannir, Jianjun Gao, Linghua Wang, Giannicola Genovese, Pavlos Msaouel

Journal: Nature Communications

PubMed ID: 41290625

Doi: 10.1038/s41467-025-65462-z.

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Cancer-associated snaR-A noncoding RNA interacts with core splicing machinery and disrupts processing of mRNA subpopulations

Authors: Sihang Zhou, Simon Lizarazo, Sandip Chorghade, Leela Mouli, Ruiying Cheng, Rajendra K C, Auinash Kalsotra, Kevin Van Bortle

Journal: Nature Communications

PubMed ID: 41290606

Doi: 10.1038/s41467-025-65448-x.

Products & Services: Molecular Biology Reagents

Glycosaminoglycans activate peptidylarginine deiminase 4 by enhancing calcium affinity

Authors: Grzegorz P. Bereta， Ewa Bielecka， Karolina Marzec， Łukasz Pijanowski， Artur P. Biela， Piotr Wilk， Marta Kamińska， Jakub Nowak， Elżbieta Wątor-Wilk， Przemysław Grudnik， Dominik Kowalczyk， Joanna Kozieł， Piotr Mydel， Marcin Poręba， Tomasz Kantyka

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 41166417

Doi: doi.org/10.1073/pnas.2508369122

Products & Services: Gene Synthesis

SmallTalk: a novel small-sized fusion tag for peptide expression and purification

Authors: Atika Tariq, Nestor G Casillas-Vega, Alma Gomez-Loredo, Xristo Zarate

Journal: FEBS Open Bio

PubMed ID: 41220226

Doi: 10.1002/2211-5463.70147

Products & Services: Gene Synthesis

Structural insights into antagonist recognition by the vasopressin V2 receptor

Authors: Tianwei Zhang, Hongli Liu, Chongzhao You, Yixiao Zhang, Youwei Xu, Benxun Pan, Canrong Wu, Sanshan Jin, Yu-Ling Yin, Kai Wu, Yue Chen, Hong Sun, Yuan Si, Yangxia Tan, Wanchao Yin, H Eric Xu, Dong Guo, Yi Jiang

Journal: Nature Communications

PubMed ID: 41188237

Doi: 10.1038/s41467-025-64735-x

Products & Services: Protein and Antibody Isolation

Anti-PD-L2 immunotherapy is efficacious against melanoma in aged hosts through IL-17 and IFNγ signalling

Authors: Carlos O Ontiveros, Myrna G Garcia, Clare E Murray, Yilun Deng, Haiyan Bai, Christopher Tanner, Bernice Leung, Xin Li, Alvaro Padron, Ryan M Reyes, Aravind Kancharla, Kah Teong Soh, Shanmugarajan Krishnan, Dhan Chand, Akshaya Balasubramanian, Courtney Hegner, Claudia V Jakubzick, Harshita B Gupta, Mary Jo Turk, Mark Sundrud, Jose R Conejo-Garcia, Tyler J Curiel

Journal: Nature Communications

PubMed ID: 41261166

Doi: 10.1038/s41467-025-65025-2.

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Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses

Authors: Tosca Holtrop, Arianne M Brandsma, Louris J Feitsma, Steffen Krohn, Petra Moerer, Frederique van den Haak, Anouk Versnel, Leonie Voss, Elsemieke M Passchier, Maaike Nederend, J H Marco Jansen, Anouk G van Mourik, Rolf T Urbanus, Diane van der Woude, Roger E G Schutgens, Rene E M Toes, Bert J C Janssen, Anja Lux, Kevin Budding, Matthias Peipp, Jeanette H W Leusen

Journal: Nature Communications

PubMed ID: 41258113

Doi: 10.1038/s41467-025-65133-z.

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Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase

Authors: Ke Wu, Zheng Wang, Deqiang Yao, Shaobai Li, Xiaozhu Wang, Yuanyuan Zhang, Mi Cao, Yafeng Shen, Shunpeng Xing, Jian Wu, Ming Lei, Pengfei Lan

Journal: Nature Communications

PubMed ID: 41290650

Doi: 10.1038/s41467-025-65488-3.

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Structural basis of regulated N-glycosylation at the secretory translocon

Authors: Melvin Yamsek, Mengxiao Ma, Roshan Jha, Yu Wan, Qianru Li, Frank Zhong, Katherine DeLong, Zhe Ji, Rajat Rohatgi, Robert J Keenan

Journal: Nature

PubMed ID: 41261126

Doi: 10.1038/s41586-025-09756-8.

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ER protein CLCC1 promotes nuclear envelope fusion in herpesviral and host processes

Authors: Bing Dai, Adrian W Sperl, Lucas Polack, Isabel Mejia, Haley Dame, Tien Huynh, Chloe Deveney, Nathalie Lavoie, Chanyoung Lee, John G Doench, Matthew D Daugherty, Ekaterina E Heldwein

Journal: Nature Communications

PubMed ID: 41271665

Doi: 10.1038/s41467-025-65115-1.

Latent-TGF-β has a domain swapped architecture

Authors: Mingliang Jin, Robert I Seed, Tiffany Shing, Li Wang, Junrui Li, Yifan Cheng, Stephen L Nishimura

Journal: Nature Communications

PubMed ID: 41290649

Doi: 10.1038/s41467-025-65465-w.

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Development of a cross-protective common cold coronavirus vaccine

Authors: Tanushree Dangi, Shiyi Li, Pablo Penaloza-MacMaster

Journal: Journal of virology

PubMed ID: 41123344

Doi: 10.1128/jvi.01526-25

Products & Services: Codon Optimization

Crystal structures of Ryanodine Receptor reveal dantrolene and azumolene interactions guiding inhibitor development

Authors: Hadiatullah Hadiatullah, Lianyun Lin, Zhiyan Wang, Rajamanikandan Sundarraj, Qing Wang, Xinru Lai, Nagomi Kurebayashi, Takuya Kobayashi, Toshiko Yamazawa, Yu Seby Chen, Wenlan Wang, Hongxia Zhao, Yiqing Yin, Takashi Murayama, Filip Van Petegem, Zhiguang Yuchi

Journal: Nature Communications

PubMed ID: 41253812

Doi: 10.1038/s41467-025-65096-1.

Products & Services: Protein and Antibody Isolation

Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22

Authors: Elisia Villemure, Tom Januario, Mingshuo Zeng, Hanna G Budayeva, Benjamin T Walters, Aaron Lictao, Ke Sherry Li, Xiaofen Ye, Caroline L Gilchrist, Bridget Hoag, Nicholas F Endres, Peter L Hsu, John Chan, Tommy K Cheung, Michael R Costa, Jean-Philippe Fortin, Noriko Ishisoko, Brett M Babin, Joyce Liu, Alexandra Frommlet, Joachim Rudolph, Robert L Yauch

Journal: Nature Communications

PubMed ID: 41184243

Doi: 10.1038/s41467-025-64669-4.

PCR-generated DNA templates enable efficient, rapid, and cost-effective mRNA synthesis

Authors: Naveen Kumar, Nicholas C Hazell, Jiani Bei, Tina Nguyen, Haitao Hu

Journal: Methods

PubMed ID: 40825451

Doi: 10.1016/j.ymeth.2025.08.007

Products & Services: PCR Cloning and Subcloning

De novo designed voltage-gated anion channels suppress neuron firing

Authors: Chen Zhou, Huican Li, Jiaxing Wang, Cheng Qian, Hui Xiong, Zhilin Chu, Qiming Shao, Xuan Li, Shijin Sun, Ke Sun, Aiqin Zhu, Jiawei Wang, Xueqin Jin, Fan Yang, Tamer M Gamal El-Din, Bo Li, Jing Huang, Kun Wu, Peilong Lu

Journal: Cell

PubMed ID: 41106381

Doi: 10.1016/j.cell.2025.09.023

Products & Services: Protein and Antibody Isolation

A novel low-cost and sensitive electrochemical biosensor based on Yb-protein/GO/SPE for rare earth element detection

Authors: Ting Zhang, Danni Ma, Jiaxing Gong, Bolun Sun, Fuman Cai

Journal: Sustainable Chemistry and Pharmacy

Doi: doi.org/10.1016/j.scp.2025.102248

Products & Services: Molecular Biology Reagents

Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity

Authors: Marta Alberti, Martina Tamburello, Stefano Salamone, Giorgio Gallinella, Cinzia Sanna, Giovanni Battista Appendino, Marco L Lolli, Alberto Massarotti, Federica Pollastro, Riccardo Miggiano

Journal: Journal of natural products

PubMed ID: 41143446

Doi: 10.1021/acs.jnatprod.5c00887

Products & Services: PCR Cloning and Subcloning

Simultaneous Monitoring of Intracellular Glucose and Extracellular Lactate in Single Cells to Assess Cell Tumorigenicity

Authors: Hui Liu, Yu Liu, Songqin Liu, Yafeng Wu

Journal: Analytical Chemistry

PubMed ID: 41035132

Doi: 10.1021/acs.analchem.5c03740

Products & Services: Recombinant Proteins

Structural basis for 3C and 3CD recruitment by enteroviral genomes during negative-strand RNA synthesis

Authors: Naba Krishna Das, Alisha Patel, Reem Abdelghani, Deepak Koirala

Journal: Nature Communications

PubMed ID: 41120315

Doi: doi.org/10.1038/s41467-025-64376-0

Products & Services: Codon Optimization PCR Cloning and Subcloning

Gibberellin triggers ATG8-dependent autophagic degradation of DELLA proteins to promote seed germination and skotomorphogenesis under nutrient starvation in Arabidopsis

Authors: Shilong Zhang, Lu Jiang, Huiru Chen, Huishan Liu, Minyu Xiong, Yuting Niu, Lingyi Xie, Lu Wang, Zhilei Mao, Tongtong Guo, Wenxiu Wang, Hong-Quan Yang

Journal: Molecular Plant

PubMed ID: 41108080

Doi: 10.1016/j.molp.2025.10.011

Products & Services: Catalog Antibodies

Pfs230 Domains 7–10 Encoded by DNA Vaccines Induce Potent Complement-Independent Transmission-Blocking Antibody Against Plasmodium falciparum

Authors: Yi Cao, Clifford T H Hayashi, Abhai K Tripathi, Eizo Takashima, Takafumi Tsuboi, Tucker B Harju, Nirbhay Kumar

Journal: The Journal of infectious diseases

PubMed ID: 41172338

Doi: doi.org/10.1093/infdis/jiaf555

Products & Services: PCR Cloning and Subcloning

RNA replicon vaccination confers long-lasting protection against H5N1 avian influenza in 23 zoo bird species

Authors: Marion Stettler, Stefan Hoby, Christian Wenker, Fabia Wyss, Elisabeth Heiderich, Lisa Butticaz, Nicolas Ruggli, Karin Darpel & Gert Zimmer

Journal: Nature Communications

PubMed ID: 41115934

Doi: 10.1038/s41467-025-64301-5

Products & Services: Protein Electrophoresis and Western

Targeted degradation of endogenous YAP by nanobody bioPROTAC inhibits tumor progression

Authors: Runhua Zhou, Huifang Wang, Gui-Ming Zhang, Yawei Liu, Xiao-Lian Liu, Zhifen Li, Guangwei Shi, Junling Yuan, Chengming Qu, Yang Li, Liang Chen, Jingnan Huang, Hongchao Zhou, Lingyun Dai, Chongzhi Bai, Jigang Wang, Le Yu, Zhijie Li & Yi-Lei Li

Journal: Nature Communications

PubMed ID: 41130953

Doi: 10.1038/s41467-025-64426-7

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Metabolic regulation of behavior by the intestinal enzyme FMO-2

Authors: Elizabeth S Kitto, Safa Beydoun, Ella Henry, Megan L Schaller, Mira Bhandari, Sarah A Easow, Angela M Tuckowski, Marshall B Howington, Ajay Bhat, Aditya Sridhar, Eugene Chung, Charles R Evans, Scott F Leiser

Journal: SCIENCE ADVANCES

PubMed ID: 41134904

Doi: 10.1126/sciadv.adx3018

Products & Services: Recombinant Proteins

Of condensates and coats - reciprocal regulation of clathrin assembly and the growth of protein networks

Authors: Brandon T. Malady, Andromachi Papagiannoula, Advika Kamatar, Susovan Sarkar, Gavin T. Lebrun, Liping Wang, Carl C. Hayden, Eileen M. Lafer, David J. Owen, Sigrid Milles & Jeanne C. Stachowiak

Journal: Nature Communications

PubMed ID: 41093888

Doi: 10.1038/s41467-025-64816-x

Mycobacterium tuberculosis-specific T cells restrain anti-cancer drug-induced neutrophilic lung inflammation in tuberculosis

Authors: Kee Woong Kwon, Tae Gun Kang, Jii Bum Lee, Eunsol Choi, Hagyu Kim, Min Chul Park, Sangwon Choi, Kyungmin Kim, Hyeong Woo Kim, Su Jin Jeong, Hye Ryun Kim, Sung Jae Shin, Sang-Jun Ha

Journal: Nature Communications

PubMed ID: 41053048

Doi: 10.1038/s41467-025-63930-0

Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies

Authors: Sebastian P Fuchs, Paula G Mondragon, Rachel Zabizhin, Shallu Tomer, Li Wang, Ethan Cook, Dawn M Dudley, Kimberly L Weisgrau, Jessica Furlott, Jennifer Coonen, Eric Alexander, Jun Xie, Guangping Gao, James M Termini, Jose M Martinez-Navio, Anjie Zhen, Ronald C Desrosiers

Journal: Nature Communications

PubMed ID: 41057323

Doi: 10.1038/s41467-025-63970-6

Journal of Controlled Release

Authors: Fei Li, Quan Wang, Tingting Wang, Chen Xiong, Ziling Chen, Hanzhi Ouyang, Xiaoding Lou, Fan Xia, Shixuan Wang, Meng Wu, Jun Dai

Journal: Journal of controlled release

Doi: 10.1016/j.jconrel.2025.114337

Products & Services: Plasmid DNA Preparation

A Robust, High-Titer, Semi-Automated, and In-Culture Antibody-Capturing Transient CHO Platform Technology

Authors: Lauren Gebhardt, Molica Abel, Jing Zhou, Audrey M Vogt, Bo Hee Shin, Sarah L Herrick Wagman, Ana Santos, Jerome Puginier, Florian M Wurm, Maria J Wurm, Guoying Grace Yan, Adedolapo Adeniyi, Sean K H Lim, Will Somers, Laura Lin, Aaron M D'Antona, Xiaotian Zhong

Journal: Antibodies

PubMed ID: 41133681

Doi: 10.3390/antib 14040087

Products & Services: Protein and Antibody Isolation

Microbial binding module employs sophisticated clustered saccharide patches to selectively adhere to mucins

Authors: Thapakorn Jaroentomeechai, Billy Veloz, Cátia O Soares, Felix Goerdeler, Ana Sofia Grosso, Christian Büll, Rebecca L Miller, Sanae Furukawa, Irene Ginés-Alcober, Víctor Taleb, Pedro Merino, Mattia Ghirardello, Ismael Compañón, Helena Coelho, Jorge S Dias, Renaud Vincentelli, Bernard Henrissat, Hiren Joshi, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Ramon Hurtado-Guerrero, Yoshiki Narimatsu

Journal: Nature Communications

PubMed ID: 41083434

Doi: 10.1038/s41467-025-63756-w

SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade

Authors: Adam J. Grippin, Christiano Marconi, Sage Copling, Nan Li, Chen Braun, Cole Woody, Elliana Young, Priti Gupta, Min Wang, Annette Wu, Seong Dong Jeong, Dhruvkumar Soni, Frances Weidert, Chao Xie, Eden Goldenberg, Andrew Kim, Chong Zhao, Anna DeVries, Paul Castillo, Rishabh Lohray, Michael K. Rooney, Benjamin R. Schrank, Yifan Wang, Yifan Ma, D3CODE Team, …Steven H. Lin

Journal: Nature

PubMed ID: 41125896

Doi: 10.1038/s41586-025-09655-y

αTIGIT-IL2 achieves tumor regression by promoting tumor-infiltrating regulatory T cell fragility in mouse models

Authors: Tianci Wang, Yupu Xu, Zhengfeng Zhang, Yaqi Wu, Long Chen, Xiaodong Zheng, Hui Peng, Qiang Zou, Rui Sun, Hongdi Ma, Haoyu Sun, Zhigang Tian & Xiaohu Zheng

Journal: Nature Communications

PubMed ID: 41107262

Doi: 10.1038/s41467-025-64296-z

Baculovirus-Mediated Gene Therapy: Targeting BIRC6 for Lung and Breast Cancer

Authors: Abril Marchesini, Santiago M Gómez Bergna, Leslie C Amorós Morales, María Florencia López, Larisa Vásquez, Silvana E Tongiani, Florencia González Morán, Víctor Romanowski, María Florencia Gottardo, Matias L Pidre

Journal: Viruses

PubMed ID: 41305480

Doi: 10.3390/v17111458

Products & Services: PCR Cloning and Subcloning Plasmid DNA Preparation

DLFea4AMPGen de novo design of antimicrobial peptides by integrating features learned from deep learning models

Authors: Han Gao, Feifei Guan, Boyu Luo, Dongdong Zhang, Wei Liu, Yuying Shen, Lingxi Fan, Guoshun Xu, Yuan Wang, Tao Tu, Ningfeng Wu, Bin Yao, Huiying Luo, Yue Teng, Jian Tian, Huoqing Huang

Journal: Nature Communications

PubMed ID: 41093853

Doi: 10.1038/s41467-025-64378-y

A human-specific regulatory mechanism revealed in a pre-implantation model

Authors: Raquel Fueyo, Sicong Wang, Olivia J. Crocker, Tomek Swigut, Hiromitsu Nakauchi & Joanna Wysocka

Journal: Nature

PubMed ID: 41034587

Doi: 10.1038/s41586-025-09571-1

Mechanism-based peroxiredoxin 3 inhibitors exploit a covalent warhead for cancer therapy

Authors: Kimberly J Nelson, Terrence L Smalley Jr, Terri Messier, Rajesh Gumpena, Uma Gandhi, Stephanie Milczarek, Aida Habibovic, Hattie Hoffman, Victoria Gibson, Robert J Hondal, W Todd Lowther, Brian Cunniff

Journal: SCIENCE ADVANCES

PubMed ID: 41171914

Doi: 41171914

Virus-inspired lipopeptide-derived nucleic acid delivery to cartilage for osteoarthritis therapy

Authors: Yu Fu, Yulan Huang, Yunjiao Wang, Zhenlan Fu, Wenyun Cai, Lu Wang, Yuchun Wu, Xing Zhou, Zhongyi Ma, Zhigang Xu, Yaqin Tang, Jing Xie, Jiayun Jiang, Robert J. Lee & Chong Li

Journal: Nature Communications

PubMed ID: 41102140

Doi: 10.1038/s41467-025-64212-5

The nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection

Authors: Tai-Ting Woo, Yuka Takeo, Mara C Harwood, Ethan T Houck, Daniel DiMaio, Billy Tsai

Journal: SCIENCE ADVANCES

PubMed ID: 41124246

Doi: 10.1126/sciadv.adz6792

DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage

Authors: Zihui Yan, Guanjin Qu, Xin Chen, Gang Zheng & Huaming Wu

Journal: Nature Communications

PubMed ID: 41102205

Doi: 10.1038/s41467-025-64230-3

Discovery of a Serine-Directed Chemical Reaction for Site-Specific Protein Modification via Phage Display Screening

Authors: Yingjie Lei, Kai Zhao, Mengzhun Guo, Liang Guo, Jinfeng Chen, Mengjiao Li, Dandan Liu, Kai Chen, Jiahao Mei, Tian Li, Bing Yang, Jing Huang, Bobo Dang

Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PubMed ID: 41108661

Doi: doi.org/10.1002/anie.202514412

Products & Services: Protein and Antibody Isolation

ROS-triggered self-assembling peptide hydrogel combining bacterial entrapment and intracellular penetration for Salmonella Typhimurium-induced enteritis therapy

Authors: Wenwen Meng, Hao Yang, Wenqian Zhang, Xueyan Li, Jiajun Sun, Ting Hu, Wei Li, Yaohong Zhu, Yong Wang, Xi Ma, Guiyan Yang, Jiufeng Wang

Journal: Chemical Engineering Journal

Doi: doi.org/10.1016/j.cej.2025.169392

Products & Services: Peptide Synthesis

Noncanonical target-strand cytosine base editing via engineered Un1Cas12f1 platform

Authors: Ziguo Song, Junfan Guo, Zhanqing Fan, Shuhong Huang, Guanglei Li, Zichang Zhao, Bingchun Chen, Shisheng Huang, Wenxin Zheng, Yinghui Wei, Yulin Chen, Xingxu Huang, Jianghuai Liu, Lina Wu, Xiaolong Wang

Journal: Nature Communications

PubMed ID: 41152217

Doi: 10.1038/s41467-025-64562-0

Products & Services: Plasmid DNA Preparation

Metal fluoride nanoregulators reverse therapeutic resistance via stemness remodeling to trigger pyroptosis for chemoimmunotherapy

Authors: Shumin Sun, Nailin Yang, Jihu Nie, Linzhu Zhang, Di Wang, Xingwei Sun, Yong Jin, Liang Cheng

Journal: Bioactive Materials

PubMed ID: 41211577

Doi: 10.1016/j.bioactmat.2025.10.011

Products & Services: Protein and Antibody Isolation

Non-canonical dihydrolipoyl transacetylase promotes chemotherapy resistance via mitochondrial tetrahydrofolate signaling

Authors: Jung Seok Hwang, JiHoon Kang, Jaehyun Kim, Kiyoung Eun, Sophia West, Hannah E Bacho, Vanessa Avalos, Sydney Shuff, Dong M Shin, Nabil F Saba, Kelly R Magliocca, Cheng-Kui Qu, Haian Fu, Suresh S Ramalingam, Andrey A Ivanov, Taro Hitosugi, Sumin Kang

Journal: Nature Communications

PubMed ID: 41062483

Doi: 10.1038/s41467-025-63892-3

Arabidopsis response to the apocarotenoid zaxinone involves interference with strigolactone signaling via binding to DWARF14

Authors: Juan C Moreno, Umar F Shahul Hameed, Aparna Balakrishna, Abdugaffor Ablazov, Kit Xi Liew, Muhammad Jamil, Jianing Mi, Kawthar Alashoor, Alexandre de Saint Germain, Stefan T Arold, Salim Al-Babili

Journal: Nature Communications

PubMed ID: 41038837

Doi: 10.1038/s41467-025-63845-w

Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment for Self-Reinforcing Photodynamic Immunotherapy

Authors: Shurong Qin, Qi Wang, Zhuangwei Zhang, Junhui Gu, Guanzhong He, Fei Zeng, Ruiyue Chen, Bangshun He, Yuzhen Wang, Meng Wang, Yujun Song

Journal: Journal of the American Chemical Society

PubMed ID: 41059938

Doi: 10.1021/jacs.5c10242

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ZBP1 pathway promotes tumor immunogenicity in thecombinationofanti-HER2therapyandepigenetic therapy

Authors: Qishan Wang, Zhihao Wu, Yuanqin Yang, Chao Yang, Haoran Deng, Xingyue Zhou, Shuting Xu, Lingling Wu, Xiaochuan Hong, Xueni Yu, Lu Lu, Liufu Deng

Journal: Cell Reports

Doi: 10.1016/j.celrep.2025.116314

Products & Services: Protein Electrophoresis and Western