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A rechargeable anti-thrombotic coating for blood-contacting devices

Authors: Hyun Ok Ham, Carolyn A Haller, Guowei Su, Erbin Dai, Madhukar S Patel, David R Liu, Jian Liu, Elliot L Chaikof

Journal: Biomaterials

PubMed ID: 34303154

Doi: 10.1016/j.biomaterials.2021.121011

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Comparative genetic analyses provide clues about capsule switching in Streptococcus suis 2 strains with different virulence levels and genetic backgrounds

Authors: Yinchu Zhu, Wenyang Dong, Jiale Ma, Yue Zhang, Xiaojun Zhong, Zihao Pan, Guangjin Liu, Zongfu Wu, Huochun Yao

Journal: Microbiol Res

PubMed ID: 34256310

Doi: 10.1016/j.micres.2021.126814

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An Integrated Approach for Discovering Noncanonical MHC-I Peptides Encoded by Small Open Reading Frames

Authors: Lei Chen, Yuanliang Zhang, Ying Yang, Yang Yang, Huihui Li, Xuan Dong, Hongwei Wang, Zhi Xie, Qian Zhao

Journal: J Am Soc Mass Spectrom

PubMed ID: 34260243

Doi: 10.1021/jasms.1c00076

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Upregulation of fibroblast growth factor 2 contributes to endometriosis through SPRYs/DUSP6/ERK signaling pathway

Authors: Xiaoyan Yu, Yuping Wang, Xiaowei Tan, Mingjiang Li

Journal: Acta Histochem

PubMed ID: 34224989

Doi: 10.1016/j.acthis.2021.151749

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Genome analysis of cotton leafroll dwarf virus reveals variability in the silencing suppressor protein, genotypes and genomic recombinants in the USA

Authors: Afsha Tabassum, Sudeep Bag, Nelson D Suassuna, Kassie N Conner, Peng Chee, Robert C Kemerait, Phillip Roberts

Journal: PLoS ONE

PubMed ID: 34232966

Doi: 10.1371/journal.pone.0252523

Products & Services: PCR Cloning and Subcloning

Comparison of alternative integration sites in the chromosome and the native plasmids of the cyanobacterium Synechocystis sp PCC 6803 in respect to expression efficiency and copy number

Authors: Csaba Nagy, Kati Thiel, Edita Mulaku, Henna Mustila, Paula Tamagnini, Eva-Mari Aro, Catarina C Pacheco, Pauli Kallio

Journal: Microb Cell Fact

PubMed ID: 34246263

Doi: 10.1186/s12934-021-01622-2

Products & Services: PCR Cloning and Subcloning

Mouse Models of Achromatopsia in Addressing Temporal "Point of No Return" in Gene-Therapy

Authors: Nan-Kai Wang, Pei-Kang Liu, Yang Kong, Sarah R Levi, Wan-Chun Huang, Chun-Wei Hsu, Hung-Hsi Wang, Nelson Chen, Yun-Ju Tseng, Peter M J Quinn, Ming-Hong Tai, Chyuan-Sheng Lin, Stephen H Tsang

Journal: Int J Mol Sci

PubMed ID: 34360834

Doi: 10.3390/ijms22158069

Products & Services: PCR Cloning and Subcloning

Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells

Authors: Benoît Malleret, Abbas El Sahili, Matthew Zirui Tay, Guillaume Carissimo, Alice Soh Meoy Ong, Wisna Novera, Jianqing Lin, Rossarin Suwanarusk, Varakorn Kosaisavee, Trang T T Chu, Ameya Sinha, Shanshan Wu Howland, Yiping Fan, Jakub Gruszczyk, Wai-Hong Tham, Yves Colin, Sebastian Maurer-Stroh, Georges Snounou, Lisa F P Ng, Jerry Kok Yen Chan, Ann-Marie Chacko, Julien Lescar, Rajesh Chandramohanadas, François Nosten, Bruce Russell, Laurent Rénia

Journal: Nat Microbiol

PubMed ID: 34294905

Doi: 10.1038/s41564-021-00939-3

Products & Services: PCR Cloning and Subcloning

Single-molecule analysis of processive double-stranded RNA cleavage by Drosophila Dicer-2

Authors: Masahiro Naganuma, Hisashi Tadakuma, Yukihide Tomari

Journal: Nat Commun

PubMed ID: 34257295

Doi: 10.1038/s41467-021-24555-1

Products & Services: PCR and Cloning

Absolute quantification of SARS-CoV-2 with Clarity Plus™ digital PCR

Authors: Shawn Yi Han Tan, Sheng Yi Milton Kwek, Huiyu Low, Yan Ling Joy Pang

Journal: Methods

PubMed ID: 34273478

Doi: 10.1016/j.ymeth.2021.07.005

Products & Services: ORF cDNA Clones/MolecularCloud

Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor

Authors: Elita Yuliantie, Wijnand J C van der Velden, Viktorija Labroska, Antao Dai, Fenghui Zhao, Sanaz Darbalaei, Giuseppe Deganutti, Tongyang Xu, Qingtong Zhou, Dehua Yang, Mette M Rosenkilde, Patrick M Sexton, Ming-Wei Wang, Denise Wootten

Journal: Biochem Pharmacol

PubMed ID: 34339714

Doi: 10.1016/j.bcp.2021.114715

Products & Services: Mutant Libraries

Functional Analyses of Four Missense Mutations Present in Patients with Atypical Femoral Fractures

Authors: Nerea Ugartondo, Núria Martínez-Gil, Mònica Esteve, Natàlia Garcia-Giralt, Neus Roca-Ayats, Diana Ovejero, Xavier Nogués, Adolfo Díez-Pérez, Raquel Rabionet, Daniel Grinberg, Susanna Balcells

Journal: Int J Mol Sci

PubMed ID: 34299011

Doi: 10.3390/ijms22147395

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Transmissible gastroenteritis virus ORF3b up-regulates miR-885-3p to counteract TNF-α production via inhibiting NF-κB pathway

Authors: Jianxiong Guo, Xiaomin Zhao, Zhihao Liu, Dan Liu, Xiaoyi Tang, Kaili Wang, Mengli Wang, Yong Huang, Dewen Tong

Journal: Vet Microbiol

PubMed ID: 34375914

Doi: 10.1016/j.vetmic.2021.109189

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The protective effect of NF-κB signaling pathway inhibitor PDTC on mice with chronic atrophic gastritis

Authors: Jun-Yan Jiang, Dai-Jiang Liu, Mao-Xia Liu

Journal: Scand J Gastroenterol

PubMed ID: 34310252

Doi: 10.1080/00365521.2021.1953130

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Phenotypic characterization of cell culture-derived hepatitis E virus subjected to different chemical treatments: Application in virus removal via nanofiltration

Authors: Shoji Ideno, Takamasa Inoue, Kadue Takahashi, Takeru Urayama, Hideki Maeno, Kaoru Takeuchi, Kaoru Sakai

Journal: J Virol Methods

PubMed ID: 34302862

Doi: 10.1016/j.jviromet.2021.114244

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Convergent epitope-specific T cell responses after SARS-CoV-2 infection and vaccination

Authors: Anastasia A Minervina, Mikhail V Pogorelyy, Allison M Kirk, E Kaitlynn Allen, Kim J Allison, Chun-Yang Lin, David C Brice, Xun Zhu, Kasi Vegesana, Gang Wu, Jeremy Chase Crawford, Stacey Schultz-Cherry, Jeremie H Estepp, Maureen A McGargill, Joshua Wolf, Paul G Thomas

Journal: medrxiv

PubMed ID: 34341799

Doi: 10.1101/2021.07.12.21260227

Products & Services: GenParts™ DNA Fragments

Unconventional Spidroin Assemblies in Aqueous Dope for Spinning into Tough Synthetic Fibers

Authors: Chun-Fei Hu, Zhi-Gang Qian, Qingfa Peng, Yaopeng Zhang, Xiao-Xia Xia

Journal: ACS Biomater Sci Eng

PubMed ID: 34259496

Doi: 10.1021/acsbiomaterials.1c00492

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A -Derived Particulate Vaccine Protects against Infection

Authors: Zennia Jean C Gonzaga, Christina Merakou, Antonio DiGiandomenico, Gregory P Priebe, Bernd H A Rehm

Journal: Vaccines (Basel)

PubMed ID: 34358220

Doi: 10.3390/vaccines9070803

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Molecular Survey of Tick-Borne Pathogens Reveals Diversity and Novel Organisms With Veterinary and Public Health Significance in Wildlife From a National Nature Reserve of China

Authors: Jifei Yang, Xiaojun Wang, Jinming Wang, Zhijie Liu, Qingli Niu, Muhammad Uzair Mukhtar, Guiquan Guan, Hong Yin

Journal: Front Vet Sci

PubMed ID: 34322535

Doi: 10.3389/fvets.2021.682963

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Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif

Authors: Mark Ultsch, Michael J Holliday, Stefan Gerhardy, Paul Moran, Suzie J Scales, Nidhi Gupta, Francesca Oltrabella, Cecilia Chiu, Wayne Fairbrother, Charles Eigenbrot, Daniel Kirchhofer

Journal: Commun Biol

PubMed ID: 34316015

Doi: 10.1038/s42003-021-02387-5

Products & Services: DNA Sequencing

T cruzi DNA polymerase beta (Tcpolβ) is phosphorylated in vitro by CK1, CK2 and TcAUK1 leading to the potentiation of its DNA synthesis activity

Authors: Edio Maldonado, Diego A Rojas, Fabiola Urbina, Aldo Solari

Journal: PLoS Negl Trop Dis

PubMed ID: 34260580

Doi: 10.1371/journal.pntd.0009588

Products & Services: DNA Sequencing

RNA editing enzyme adenosine deaminases acting on RNA 1 deficiency increases the sensitivity of non-small cell lung cancer cells to anlotinib by regulating CX3CR1-fractalkine expression

Authors: Min Wu, Mengmeng Jin, Xiaohui Cao, Kun Qian, Lei Zhao

Journal: Drug Dev Res

PubMed ID: 34319598

Doi: 10.1002/ddr.21861

Products & Services: DNA Sequencing

Exosome-delivered miR-221/222 exacerbates tumor liver metastasis by targeting SPINT1 in colorectal cancer

Authors: Fei Tian, Peiyun Wang, Dan Lin, Jiajia Dai, Qibing Liu, Yu Guan, Yang Zhan, Yichen Yang, Wenpeng Wang, Jiefu Wang, Jia Liu, Lei Zheng, Yan Zhuang, Jun Hu, Junfeng Wang, Dalu Kong, Kegan Zhu

Journal: Cancer Sci

PubMed ID: 34125460

Doi: 10.1111/cas.15028

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SPNS2 enables T cell egress from lymph nodes during an immune response

Authors: Martyna Okuniewska, Victoria Fang, Audrey Baeyens, Varsha Raghavan, June-Yong Lee, Dan R Littman, Susan R Schwab

Journal: Cell Rep

PubMed ID: 34260944

Doi: 10.1016/j.celrep.2021.109368

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ZIC2 upregulates lncRNA SNHG12 expression to promote endometrial cancer cell proliferation and migration by activating the Notch signaling pathway

Authors: Pengyu Cai, Gaijuan Li, Mingxiu Wu, Bin Zhang, Hong Bai

Journal: Mol Med Rep

PubMed ID: 34278490

Doi: 10.3892/mmr.2021.12271

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De novo biosynthesis of garbanzol and fustin in Streptomyces albus based on a potential flavanone 3-hydroxylase with 2-hydroxylase side activity

Authors: Laura Marín, Ignacio Gutiérrez-Del-Río, Claudio Jesús Villar, Felipe Lombó

Journal: Microb Biotechnol

PubMed ID: 34216097

Doi: 10.1111/1751-7915.13874

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Condition-dependent structural collapse in the intrinsically disordered N-terminal domain of prion protein

Authors: Eric H-L Chen, Kuei-Ming Lin, Jason C Sang, Meng-Ru Ho, Chih-Hsuan Lee, Orion Shih, Chun-Jen Su, Yi-Qi Yeh, U-Ser Jeng, Rita P-Y Chen

Journal: IUBMB Life

PubMed ID: 34288372

Doi: 10.1002/iub.2528

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Evolution of a σ-(c-di-GMP)-anti-σ switch

Authors: Maria A Schumacher, Kelley A Gallagher, Neil A Holmes, Govind Chandra, Max Henderson, David T Kysela, Richard G Brennan, Mark J Buttner

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34290147

Doi: 10.1073/pnas.2105447118

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The identification and structural analysis of potential 14-3-3 interaction sites on the bone regulator protein Schnurri-3

Authors: Lorenzo Soini, Seppe Leysen, Tom Crabbe, Jeremy Davis, Christian Ottmann

Journal: Acta Crystallogr F Struct Biol Commun

PubMed ID: 34341191

Doi: 10.1107/S2053230X21006658

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Selective Moonlighting Cell-Penetrating Peptides

Authors: Rafael Morán-Torres, David A Castillo González, Maria Luisa Durán-Pastén, Beatriz Aguilar-Maldonado, Susana Castro-Obregón, Gabriel Del Rio

Journal: Pharmaceutics

PubMed ID: 34452080

Doi: 10.3390/pharmaceutics13081119

Products & Services: Peptide Synthesis

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

Authors: Kanchan Devkota, Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau, Pegah Ghiabi, Taraneh Hajian, Peter Loppnau, Albina Bolotokova, Karla J F Satchell, Ke Wang, Deyao Li, Jing Liu, David Smil, Minkui Luo, Jian Jin, Paul V Fish, Peter J Brown, Masoud Vedadi

Journal: SLAS Discov

PubMed ID: 34192965

Doi: 10.1177/24725552211026261

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Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

Authors: Lingshu Wang, Tongqing Zhou, Yi Zhang, Eun Sung Yang, Chaim A Schramm, Wei Shi, Amarendra Pegu, Olamide K Oloninyi, Amy Ransier, Samuel Darko, Sandeep R Narpala, Christian Hatcher, David R Martinez, Yaroslav Tsybovsky, Emily Phung, Olubukola M Abiona, Evan M Cale, Lauren A Chang, Kizzmekia S Corbett, Anthony T DiPiazza, Ingelise J Gordon, Kwanyee Leung, Tracy Liu, Rosemarie D Mason, Alexandra Nazzari, Laura Novik, Adam S Olia, Tyler Stephens, Christopher D Stringham, Chloe Adrienna Talana, I-Ting Teng, Danielle Wagner, Alicia T Widge, Baoshan Zhang, Mario Roederer, Julie E Ledgerwood, Tracy J Ruckwardt, Martin R Gaudinski, Ralph S Baric, Barney S Graham, Adrian B McDermott, Daniel C Douek, Peter D Kwong, John R Mascola, Nancy J Sullivan, John Misasi

Journal: Science

PubMed ID: 33655252

Doi: 10.1126/science.abh1766

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Bisulfite Amplicon Sequencing Can Detect Glia and Neuron Cell-Free DNA in Blood Plasma

Authors: Zac Chatterton, Natalia Mendelev, Sean Chen, Walter Carr, Gary H Kamimori, Yongchao Ge, Andrew J Dwork, Fatemeh Haghighi

Journal: Front Mol Neurosci

PubMed ID: 34276305

Doi: 10.3389/fnmol.2021.672614

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A GRA2 minimal promoter improves the efficiency of TATi / Tet-Off conditional regulation of gene expression in Toxoplasma gondii

Authors: Mohammad Farouq Sharifpour, Shadi Khadiv, Markus Meissner, Milton M McAllister

Journal: Mol Biochem Parasitol.

PubMed ID: 34051228

Doi: 10.1016/j.molbiopara.2021.111384

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Molecular and biological characterization of severe strain infecting soybean in India

Authors: Nagamani Sandra, Ankita Tripathi, S K Lal, Bikash Mandal, Rakesh Kumar Jain

Journal: 3 Biotech

PubMed ID: 34458057

Doi: 10.1007/s13205-021-02925-2

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The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

Authors: James M Murithi, Ioanna Deni, Charisse Flerida A Pasaje, John Okombo, Jessica L Bridgford, Nina F Gnädig, Rachel L Edwards, Tomas Yeo, Sachel Mok, Anna Y Burkhard, Olivia Coburn-Flynn, Eva S Istvan, Tomoyo Sakata-Kato, Maria G Gomez-Lorenzo, Annie N Cowell, Kathryn J Wicht, Claire Le Manach, Gavreel F Kalantarov, Sumanta Dey, Maëlle Duffey, Benoît Laleu, Amanda K Lukens, Sabine Ottilie, Manu Vanaerschot, Ilya N Trakht, Francisco-Javier Gamo, Dyann F Wirth, Daniel E Goldberg, Audrey R Odom John, Kelly Chibale, Elizabeth A Winzeler, Jacquin C Niles, David A Fidock

Journal: Cell Chem Biol

PubMed ID: 34233174

Doi: 10.1016/j.chembiol.2021.06.006

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Genome-Wide Identification and Expression Analysis of Tomato Gene Family during Development and Stress

Authors: Lu Yang, Haohao Cao, Xiaoping Zhang, Liangxian Gui, Qiang Chen, Gui Qian, Jiaxin Xiao, Zhengguo Li

Journal: Int J Mol Sci

PubMed ID: 34299327

Doi: 10.3390/ijms22147708

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YB-1 Is Altered in Pregnancy-Associated Disorders and Affects Trophoblast in Vitro Properties via Alternation of Multiple Molecular Traits

Authors: Violeta Stojanovska, Aneri Shah, Katja Woidacki, Florence Fischer, Mario Bauer, Jonathan A Lindquist, Peter R Mertens, Ana C Zenclussen

Journal: Int J Mol Sci

PubMed ID: 34281280

Doi: 10.3390/ijms22137226

Products & Services: Proteins, Expression, Isolation and Analysis

Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth

Authors: Fangrui Wu, Shenyou Nie, Yuan Yao, Tong Huo, Xin Li, Xiaowei Wu, Jidong Zhao, Yi-Lun Lin, Yinjie Zhang, Qianxing Mo, Yongcheng Song

Journal: Theranostics

PubMed ID: 34373735

Doi: 10.7150/thno.56737

Products & Services: Mammalian Expression

RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer

Authors: Mark P Labrecque, Lisha G Brown, Ilsa M Coleman, Bryce Lakely, Nicholas J Brady, John K Lee, Holly M Nguyen, Dapei Li, Brian Hanratty, Michael C Haffner, David S Rickman, Lawrence D True, Daniel W Lin, Hung-Ming Lam, Joshi J Alumkal, Eva Corey, Peter S Nelson, Colm Morrissey

Journal: Cancer Res

PubMed ID: 34312180

Doi: 10.1158/0008-5472.CAN-21-0307

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Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex

Authors: Maria Velkova, Nicola Silva, Maria Rosaria Dello Stritto, Alexander Schleiffer, Pierre Barraud, Markus Hartl, Verena Jantsch

Journal: PLoS Genet

PubMed ID: 34252074

Doi: 10.1371/journal.pgen.1009663

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Genomic identification of nitrogen assimilation-related genes and transcriptional characterization of their responses to nitrogen in allotetraploid rapeseed

Authors: Yue Wang, Ying-Peng Hua, Ting Zhou, Jin-Yong Huang, Cai-Peng Yue

Journal: Mol Biol Rep

PubMed ID: 34327662

Doi: 10.1007/s11033-021-06599-0

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Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor

Authors: Fenghui Zhao, Chao Zhang, Qingtong Zhou, Kaini Hang, Xinyu Zou, Yan Chen, Fan Wu, Qidi Rao, Antao Dai, Wanchao Yin, Dan-Dan Shen, Yan Zhang, Tian Xia, Raymond C Stevens, H Eric Xu, Dehua Yang, Lihua Zhao, Ming-Wei Wang

Journal: Elife

PubMed ID: 34254582

Doi: 10.7554/eLife.68719

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Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

Authors: Maryam Izadi, Eric Seemann, Dirk Schlobinski, Lukas Schwintzer, Britta Qualmann, Michael M Kessels

Journal: Elife

PubMed ID: 34264190

Doi: 10.7554/eLife.67718

Products & Services: Proteins, Expression, Isolation and Analysis

HDAC inhibitors induce LIFR expression and promote a dormancy phenotype in breast cancer

Authors: Miranda E Clements, Lauren Holtslander, Courtney Edwards, Vera Todd, Samuel D R Dooyema, Kennady Bullock, Kensey Bergdorf, Cynthia A Zahnow, Roisin M Connolly, Rachelle W Johnson

Journal: Oncogene

PubMed ID: 34247191

Doi: 10.1038/s41388-021-01931-1

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Low efficiency of leucocyte plugging-based drug delivery to cancer in mice

Authors: Baifeng Qian, Andreas Termer, Christof M Sommer, Arianeb Mehrabi, Eduard Ryschich

Journal: Drug Deliv Transl Res

PubMed ID: 34319578

Doi: 10.1007/s13346-021-01028-y

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Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model

Authors: Johannes Gebert, Ozkan Gelincik, Mine Oezcan-Wahlbrink, Jason D Marshall, Alejandro Hernandez-Sanchez, Katharina Urban, Mark Long, Eduardo Cortes, Elena Tosti, Eva-Maria Katzenmaier, Yurong Song, Ali Elsaadi, Nan Deng, Eduardo Vilar, Vera Fuchs, Nina Nelius, Yan P Yuan, Aysel Ahadova, Shizuko Sei, Robert H Shoemaker, Asad Umar, Lei Wei, Song Liu, Peer Bork, Winfried Edelmann, Magnus von Knebel Doeberitz, Steven M Lipkin, Matthias Kloor

Journal: Gastroenterology

PubMed ID: 34224739

Doi: 10.1053/j.gastro.2021.06.073

Products & Services: Proteins, Expression, Isolation and Analysis

A single residue can modulate nanocage assembly in salt dependent ferritin

Authors: Mantu Kumar, Joanna Markiewicz-Mizera, Julian David Janna Olmos, Piotr Wilk, Przemysław Grudnik, Artur P Biela, Małgorzata Jemioła-Rzemińska, Andrzej Górecki, Soumyananda Chakraborti, Jonathan G Heddle

Journal: Nanoscale

PubMed ID: 34195748

Doi: 10.1039/d1nr01632f

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Coatomer protein COPƐ, a novel NS1-interacting protein, promotes the replication of Porcine Parvovirus via attenuation of the production of type I interferon

Authors: Songbiao Chen, Nannan Chen, Bichen Miao, Jiang Peng, Xuezhi Zhang, Caiyi Chen, Xiujuan Zhang, Lingling Chang, Qian Du, Yong Huang, Dewen Tong

Journal: Vet Microbiol

PubMed ID: 34365051

Doi: 10.1016/j.vetmic.2021.109188

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Overlapping Functions of the Paralogous Proteins AtPAP2 and AtPAP9 in

Authors: Renshan Zhang, Xiaoqian Guan, Meijing Yang, Yee-Song Law, Chia Pao Voon, Junran Yan, Feng Sun, Boon Leong Lim

Journal: Int J Mol Sci

PubMed ID: 34298863

Doi: 10.3390/ijms22147243

SARS-CoV-2 Infection in Dogs and Cats from Southern Germany and Northern Italy during the First Wave of the COVID-19 Pandemic

Authors: Julia Klaus, Eric Zini, Katrin Hartmann, Herman Egberink, Anja Kipar, Michèle Bergmann, Carlo Palizzotto, Shan Zhao, Francesco Rossi, Vittoria Franco, Federico Porporato, Regina Hofmann-Lehmann, Marina L Meli

Journal: Viruses

PubMed ID: 34452319

Doi: 10.3390/v13081453

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Membranotropic and biological activities of the membrane fusion peptides from SARS-CoV spike glycoprotein: The importance of the complete internal fusion peptide domain

Authors: Luis Guilherme Mansor Basso, Ana Eliza Zeraik, Ana Paula Felizatti, Antonio José Costa-Filho

Journal: Biochim Biophys Acta Biomembr

PubMed ID: 34274319

Doi: 10.1016/j.bbamem.2021.183697

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CDK1 controls CHMP7-dependent nuclear envelope reformation

Authors: Alberto T Gatta, Yolanda Olmos, Caroline L Stoten, Qu Chen, Peter B Rosenthal, Jeremy G Carlton

Journal: Elife

PubMed ID: 34286694

Doi: 10.7554/eLife.59999

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Genome-Wide Characterization of B-Box Gene Family and Its Roles in Responses to Light Quality and Cold Stress in Tomato

Authors: Xin Bu, Xiujie Wang, Jiarong Yan, Ying Zhang, Shunyuan Zhou, Xin Sun, Youxin Yang, Golam Jalal Ahammed, Yufeng Liu, Mingfang Qi, Feng Wang, Tianlai Li

Journal: Front Plant Sci

PubMed ID: 34290726

Doi: 10.3389/fpls.2021.698525

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Endomembrane-Targeting Effectors Modulate PAMP Triggered Immune Responses in Plants

Authors: Md Musharaf Hossain, Edel Pérez-López, Christopher D Todd, Yangdou Wei, Peta C Bonham-Smith

Journal: Front Microbiol

PubMed ID: 34276588

Doi: 10.3389/fmicb.2021.651279

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ANXA10 promotes melanoma metastasis by suppressing E3 ligase TRIM41-directed PKD1 degradation

Authors: Xuerui Zhang, Zhaoqing Hu, Xinran Wang, Lin Li, Banghui Zhu, Xiaolei Lin, Jing Zhang, Zichun Hua

Journal: Cancer Lett

PubMed ID: 34324862

Doi: 10.1016/j.canlet.2021.07.033

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Neofunctionalisation of the Sli gene leads to self-compatibility and facilitates precision breeding in potato

Authors: Ernst-Jan Eggers, Ate van der Burgt, Sjaak A W van Heusden, Michiel E de Vries, Richard G F Visser, Christian W B Bachem, Pim Lindhout

Journal: Nat Commun

PubMed ID: 34230471

Doi: 10.1038/s41467-021-24267-6

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Targeting TRAF3IP2 alleviates high glucose-induced cardiomyocyte inflammation and apoptosis

Authors: Jing Wei, Tao Yan, Yuanhong Liang

Journal: Drug Dev Res

PubMed ID: 34260107

Doi: 10.1002/ddr.21856

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Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1

Authors: Naotaka Tsutsumi, Qianhui Qu, Maša Mavri, Maibritt S Baggesen, Shoji Maeda, Deepa Waghray, Christian Berg, Brian K Kobilka, Mette M Rosenkilde, Georgios Skiniotis, K Christopher Garcia

Journal: Immunity

PubMed ID: 34216564

Doi: 10.1016/j.immuni.2021.06.001

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Human low-density lipoprotein receptor plays an important role in hepatitis B virus infection

Authors: Yingying Li, Guangxiang Luo

Journal: PLoS Pathog

PubMed ID: 34293069

Doi: 10.1371/journal.ppat.1009722

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Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus

Authors: Elvira Tarasova, Sonali Dhindwal, Matthew Popp, Sakeenah Hussain, Reza Khayat

Journal: MBio

PubMed ID: 34311576

Doi: 10.1128/mBio.00763-21

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Fulvic acid enhances drought resistance in tea plants by regulating the starch and sucrose metabolism and certain secondary metabolism

Authors: Chen Qiu, Jianhao Sun, Jiazhi Shen, Shuning Zhang, Yiqian Ding, Zhongshuai Gai, Kai Fan, Lubin Song, Bo Chen, Zhaotang Ding, Yu Wang

Journal: J Proteomics

PubMed ID: 34298183

Doi: 10.1016/j.jprot.2021.104337

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Antibodies Targeting Two Epitopes in SARS-CoV-2 Neutralize Pseudoviruses with the Spike Proteins from Different Variants

Authors: Chee-Hing Yang, Hui-Chun Li, Wen-Han Lee, Shih-Yen Lo

Journal: Pathogens

PubMed ID: 34358019

Doi: 10.3390/pathogens10070869

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TIMELESS-TIPIN and UBXN-3 promote replisome disassembly during DNA replication termination in Caenorhabditis elegans

Authors: Yisui Xia, Ryo Fujisawa, Tom D Deegan, Remi Sonneville, Karim P M Labib

Journal: EMBO J

PubMed ID: 34269473

Doi: 10.15252/embj.2021108053

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Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation

Authors: Joel D Allen, Himanshi Chawla, Firdaus Samsudin, Lorena Zuzic, Aishwary Tukaram Shivgan, Yasunori Watanabe, Wan-Ting He, Sean Callaghan, Ge Song, Peter Yong, Philip J M Brouwer, Yutong Song, Yongfei Cai, Helen M E Duyvesteyn, Tomas Malinauskas, Joeri Kint, Paco Pino, Maria J Wurm, Martin Frank, Bing Chen, David I Stuart, Rogier W Sanders, Raiees Andrabi, Dennis R Burton, Sai Li, Peter J Bond, Max Crispin

Journal: Biochemistry

PubMed ID: 34213308

Doi: 10.1021/acs.biochem.1c00279

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Seasonal Variation in Transcriptomic Profiling of Fully Developed Tuberous Roots Enriches Candidate Genes in Essential Metabolic Pathways and Phytohormone Signaling

Authors: Qianqian Xiang, Siyuan Hu, Ayalew Ligaba-Osena, Jiayao Yang, Fudan Tong, Wanli Guo

Journal: Front Plant Sci

PubMed ID: 34305963

Doi: 10.3389/fpls.2021.659645

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Emerging Insights into Keratin 16 Expression during Metastatic Progression of Breast Cancer

Authors: Maha Elazezy, Sandra Schwentesius, Luisa Stegat, Harriet Wikman, Stefan Werner, Wael Y Mansour, Antonio Virgilio Failla, Sven Peine, Volkmar Müller, Jean Paul Thiery, Majid Ebrahimi Warkiani, Klaus Pantel, Simon A Joosse

Journal: Cancers (Basel)

PubMed ID: 34359774

Doi: 10.3390/cancers13153869

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A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors

Authors: Subramanyam Vankadara, Yun Xuan Wong, Boping Liu, Yi Yang See, Li Hong Tan, Qian Wen Tan, Gang Wang, Ratna Karuna, Xue Guo, Shu Ting Tan, Jia Yi Fong, Joma Joy, C S Brian Chia

Journal: Bioorg Med Chem Lett

PubMed ID: 34271072

Doi: 10.1016/j.bmcl.2021.128263

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Overexpression of Douglas-Fir () in Induces Embryonic Programs and Embryo-like Structures in the Mutant but Not in Wild Type Plants

Authors: Mariana A Vetrici, Dmytro P Yevtushenko, Santosh Misra

Journal: Plants (Basel)

PubMed ID: 34451571

Doi: 10.3390/plants10081526

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Differential Serotonin Uptake Mechanisms at the Human Maternal-Fetal Interface

Authors: Petra Baković, Maja Kesić, Maja Perić, Ivona Bečeheli, Marina Horvatiček, Meekha George, Lipa Čičin-Šain, Gernot Desoye, Christian Wadsack, Ute Panzenboeck, Jasminka Štefulj

Journal: Int J Mol Sci

PubMed ID: 34360573

Doi: 10.3390/ijms22157807

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Nanopore Sequencing Accurately Identifies the Cisplatin Adduct on DNA

Authors: Fubo Ma, Shuanghong Yan, Jinyue Zhang, Yu Wang, Liying Wang, Yuqin Wang, Shanyu Zhang, Xiaoyu Du, Panke Zhang, Hong-Yuan Chen, and Shuo Huang

Journal: ACS Sensors

PubMed ID: 34319692

Doi: doi.org/10.1021/acssensors.1c01212

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Mapping Potential Engineering Sites of Mycobacterium smegmatis porin A (MspA) to Form a Nanoreactor

Authors: Jinyue Zhang, Jiao Cao, Wendong Jia, Shanyu Zhang, Shuanghong Yan, Yuqin Wang, Panke Zhang, Hong-Yuan Chen, Wenfei Li, Shuo Huang

Journal: ACS Sens.

PubMed ID: 34107684

Doi: 10.1021/acssensors.1c00792

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A Live-Attenuated Zika Virus Vaccine with High Production Capacity Confers Effective Protection in Neonatal Mice

Authors: Xianmiao Ye, Xinglong Liu, Tao Shu, Weiqi Deng, Min Liao, Yali Zheng, Xuehua Zheng, Xiaoyan Zhang, Ting Li, Wenxia Fan, Linbing Qu, Ling Chen, Feng Li, Liqiang Feng

Journal: J Virol.

PubMed ID: 33910950

Doi: 10.1128/JVI.00383-21

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Evaluation of Benzylpenicillin as an Internal Standard for Measurement of Piperacillin Bone Concentrations via Microdialysis

Authors: Martin Bruun Knudsen, Mats Bue, Louise L Pontoppidan, Magnus A Hvistendahl, Kjeld S?balle, Maiken Stilling, Pelle Hanberg

Journal: J Pharm Sci

PubMed ID: 34102200

Doi: 10.1016/j.xphs.2021.06.008

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Versatile and efficient in vivo genome editing with compact Streptococcus pasteurianus Cas9

Authors: Zhiquan Liu, Siyu Chen, Wanhua xie, Yuning Song, Jinze Li, Liangxue Lai, Zhanjun Li

Journal: Molecular Therapy

Doi: doi.org/10.1016/j.ymthe.2021.06.013

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Structural basis of substrate recognition and translocation by human ABCA4

Authors: Tian Xie， Zike Zhang, Qi Fang, Bowen Du& Xin Gong

Journal: Nature Communications

PubMed ID: 34158497

Doi: doi.org/10.1038/s41467-021-24194-6

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LncRSPH9-4 Facilitates Meningitic Escherichia coli-Caused Blood-Brain Barrier Disruption via miR-17-5p/MMP3 Axis

Authors: Bojie Xu , Ruicheng Yang, Jiyang Fu, Bo Yang, Jiaqi Chen , Chen Tan, Huanchun Chen and Xiangru Wang

Journal: International Journal of Molecular Sciences

PubMed ID: 34198485

Doi: 10.3390/ijms22126343

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Peptides affecting outer membrane lipid asymmetry (MlaA-OmpC/F) system reduce avian pathogenic (APEC) colonization in chickens

Authors: Dipak Kathayat, Gary Closs, Yosra A Helmy, Dhanashree Lokesh, Sochina Ranjit, Gireesh Rajashekara

Journal: Appl Environ Microbiol

PubMed ID: 34132592

Doi: 10.1128/AEM.00567-21

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Metformin-Inducible Small Heterodimer Partner Interacting Leucine Zipper Protein Ameliorates Intestinal Inflammation

Authors: SeungCheon Yang, Jin-Sil Park, Sun-Hee Hwang, Keun-Hyung Cho, Hyun Sik Na, JeongWon Choi, Jooyeon Jhun, Seung-Jun Kim, Bo-In Lee, Sung-Hwan Park, Mi-La Cho

Journal: Front Immunol

PubMed ID: 34211461

Doi: 10.3389/fimmu.2021.652709

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Histone demethylase PHF8 promotes cell growth and metastasis of non-small-cell lung cancer through activating Wnt/β-catenin signaling pathway

Authors: Yan Hu, Hanshuo Mu, Ying Yang

Journal: Histol Histopathol

PubMed ID: 34100557

Doi: 10.14670/HH-18-349

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LINC00839 Regulates Proliferation, Migration, Invasion, Apoptosis and Glycolysis in Neuroblastoma Cells Through miR-338-3p/GLUT1 Axis

Authors: Lixia Yang, Liangyan Pei, Jilong Yi

Journal: Neuropsychiatr Dis Treat

PubMed ID: 34188473

Doi: 10.2147/NDT.S309467

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Humoral and cellular immune responses against SARS-CoV-2 variants and human coronaviruses after single BNT162b2 vaccination

Authors: Metodi V Stankov, Anne Cossmann, Agnes Bonifacius, Alexandra Dopfer-Jablonka, Gema Morillas Ramos, Nina Gödecke, Anna Zychlinsky Scharff, Christine Happle, Anna-Lena Boeck, Anh Thu Tran, Isabell Pink, Marius M Hoeper, Rainer Blasczyk, Martin S Winkler, Inga Nehlmeier, Amy Kempf, Heike Hofmann-Winkler, Markus Hoffmann, Britta Eiz-Vesper, Stefan Pöhlmann, Georg M N Behrens

Journal: Clin Infect Dis

PubMed ID: 34134134

Doi: 10.1093/cid/ciab555

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Dissecting Out the Molecular Mechanism of Insecticidal Activity of Ostreolysin A6/Pleurotolysin B Complexes on Western Corn Rootworm

Authors: Matej Milijaš Jotić, Anastasija Panevska, Ioan Iacovache, Rok Kostanjšek, Martina Mravinec, Matej Skočaj, Benoît Zuber, Ana Pavšič, Jaka Razinger, Špela Modic, Francesco Trenti, Graziano Guella, Kristina Sepčić

Journal: Toxins (Basel)

PubMed ID: 34209983

Doi: 10.3390/toxins13070455

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The local anesthetic ropivacaine suppresses progression of breast cancer by regulating miR-27b-3p/YAP axis

Authors: Lu Zhao, Shuang Han, Junde Hou, Wenhui Shi, Yonglei Zhao, Yongxue Chen

Journal: Aging (Albany NY)

PubMed ID: 34126594

Doi: 10.18632/aging.203160

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Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation

Authors: Sandra Torres, Estel Solsona-Vilarrasa, Susana Nuñez, Nuria Matías, Naroa Insausti-Urkia, Fernanda Castro, Mireia Casasempere, Gemma Fabriás, Josefina Casas, Carlos Enrich, José C Fernández-Checa, Carmen Garcia-Ruiz

Journal: Redox Biol

PubMed ID: 34175669

Doi: 10.1016/j.redox.2021.102052

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Allelic diversification after transposable element exaptation promoted as the master sex determining gene of sablefish

Authors: Amaury Herpin, Manfred Schartl, Alexandra Depincé, Yann Guiguen, Julien Bobe, Aurélie Hua-Van, Edward S Hayman, Anna Octavera, Goro Yoshizaki, Krista M Nichols, Giles W Goetz, J Adam Luckenbach

Journal: Genome Res

PubMed ID: 34183453

Doi: 10.1101/gr.274266.120

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Self-assembled small messenger RNA nanospheres for efficient therapeutic apoptin expression and synergistic Gene-Chemotherapy of breast cancer

Authors: Yuxia Tang, Xiang Liao, Chunyan Wang, Ying Liu, Jing Pan, Ying Tian, Zhaogang Teng, Guangming Lu

Journal: J Colloid Interface Sci

PubMed ID: 34192626

Doi: 10.1016/j.jcis.2021.06.061

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MiR-513b-5p represses autophagy during the malignant progression of hepatocellular carcinoma by targeting PIK3R3

Authors: Wei Jin, Yilei Liang, Shuyou Li, Guoxiang Lin, Haiying Liang, Zhenni Zhang, Weiming Zhang, Rongjun Nie

Journal: Aging (Albany NY)

PubMed ID: 34120890

Doi: 10.18632/aging.203135

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Mulberroside A repairs high fructose diet-induced damage of intestinal epithelial and blood-brain barriers in mice: A potential for preventing hippocampal neuroinflammatory injury

Authors: Yu R,Wen S,Wang Q,Wang C,Zhang L,Wu X,Li J,Kong L

Journal: Journal of neurochemistry

PubMed ID: 33205422

Doi: 10.1111/jnc.15242

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Inherent backbone dynamics fine-tune the functional plasticity of Tudor domains

Authors: Ashish A Kawale, Björn M Burmann

Journal: Structure

PubMed ID: 34197736

Doi: 10.1016/j.str.2021.06.007

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Design, synthesis, biological evaluation and structural characterization of novel GEBR library PDE4D inhibitors

Authors: Chiara Brullo, Federica Rapetti, Sara Abbate, Tommaso Prosdocimi, Archimede Torretta, Marta Semrau, Matteo Massa, Silvana Alfei, Paola Storici, Emilio Parisini, Olga Bruno

Journal: Eur J Med Chem

PubMed ID: 34171658

Doi: 10.1016/j.ejmech.2021.113638

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A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy

Authors: Akemi Kosaka, Yuki Yajima, Mayumi Hatayama, Katsuya Ikuta, Takaaki Sasaki, Noriko Hirai, Syunsuke Yasuda, Marino Nagata, Ryusuke Hayashi, Shohei Harabuchi, Kenzo Ohara, Mizuho Ohara, Takumi Kumai, Kei Ishibashi, Yui Hirata-Nozaki, Toshihiro Nagato, Kensuke Oikawa, Yasuaki Harabuchi, Esteban Celis, Toshikatsu Okumura, Yoshinobu Ohsaki, Hiroya Kobayashi, Takayuki Ohkuri

Journal: Cancer Sci

PubMed ID: 34009705

Doi: 10.1111/cas.14973

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Pharmacokinetics, Immunogenicity and Safety Study for SHR-1309 Injection and Perjeta® in Healthy Chinese Male Volunteers

Authors: Yingzi Cui, Dongyang Cui, Xinran Ren, Xuesong Chen, Guangwen Liu, Zhengzhi Liu, Yanli Wang, Xinyao Qu, Yicheng Zhao, Haimiao Yang

Journal: Front Pharmacol

PubMed ID: 34149414

Doi: 10.3389/fphar.2021.660541

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Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing

Authors: Phuc Leo H Vo, Christopher Acree, Melissa L Smith, Samuel H Sternberg

Journal: Mob DNA

PubMed ID: 34103093

Doi: 10.1186/s13100-021-00242-2

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Cellulosome Localization Patterns Vary across Life Stages of Anaerobic Fungi

Authors: Stephen P Lillington, William Chrisler, Charles H Haitjema, Sean P Gilmore, Chuck R Smallwood, Vaithiyalingam Shutthanandan, James E Evans, Michelle A O'Malley

Journal: MBio

PubMed ID: 34061594

Doi: 10.1128/mBio.00832-21

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Nuclear factor kappa B inhibitor suppresses experimental autoimmune neuritis in mice via declining macrophages polarization to M1 type

Authors: Donghui Shen, Fengna Chu, Yue Lang, Chao Zheng, Chunrong Li, Kangding Liu, Jie Zhu

Journal: Clin Exp Immunol

PubMed ID: 34118070

Doi: 10.1111/cei.13637

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Identification of testicular Foxq1 as a critical modulator of lactate metabolism in mouse Sertoli cells

Authors: Zetao Liu, Mingyou Yuan, Xiangxiang Meng, Haiwen Bie, Shaobo Yao

Journal: Histochem Cell Biol

PubMed ID: 34091745

Doi: 10.1007/s00418-021-01994-x

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Mummichog gill and operculum exhibit functionally consistent claudin-10 paralog profiles and Claudin-10c hypersaline response

Authors: Chun Chih Chen, William S Marshall, George N Robertson, Regina R F Cozzi, Scott P Kelly

Journal: Biol Open

PubMed ID: 34156063

Doi: 10.1242/bio.058868

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Multi-locus sequence typing analysis of Mycoplasma synoviae isolates reveals unique sequence types in China

Authors: Xiaorong Zhang, Yang Chen, Di Xie, Mengjiao Guo, Shuang Ma, Mengyao Chen, Dianfeng Chu, Yantao Wu

Journal: Vet Microbiol

PubMed ID: 34166888

Doi: 10.1016/j.vetmic.2021.109101

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The Rac-GAP alpha2-chimaerin signals via CRMP2 and stathmins in the development of the ocular motor system

Authors: Luis Carretero-Rodriguez, Ragnheiður Guðjónsdóttir, Ivana Poparic, Madeline Louise Reilly, Mary Chol, Isaac H Bianco, Marco Chiapello, Renata Feret, Michael J Deery, Sarah Guthrie

Journal: J Neurosci

PubMed ID: 34168008

Doi: 10.1523/JNEUROSCI.0983-19.2021

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