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Functional Insights into Silymarin as an Antiviral Agent against Enterovirus A71 (EV-A71)

Authors: Salima Lalani, Malihe Masomian, Chit Laa Poh

Journal: Int J Mol Sci

PubMed ID: 34445463

Doi: 10.3390/ijms22168757

Products & Services: Plasmid DNA Preparation

Genome-wide characterization and expression profiling of the Phospholipase C (PLC) gene family in three orchids of economic importance

Authors: Madhvi Kanchan, Thakku R Ramkumar, Jaspreet K Sembi

Journal: J Genet Eng Biotechnol

PubMed ID: 34420115

Doi: 10.1186/s43141-021-00217-z

Products & Services: Protein Tools

PGLYRP2 as a novel biomarker for the activity and lipid metabolism of systemic lupus erythematosus

Authors: Hui Li, Defang Meng, Jieting Jia, Hua Wei

Journal: Lipids Health Dis

PubMed ID: 34461924

Doi: 10.1186/s12944-021-01515-8

Products & Services: Custom DNA/RNA Oligos

Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease

Authors: Mayada Metwally, Ali Bayoumi, Anis Khan, Leon A Adams, Rocio Aller, Carmelo García-Monzón, María Teresa Arias-Loste, Elisabetta Bugianesi, Luca Miele, Alisi Anna, Olivier Latchoumanin, Shuanglin Han, Shafi Alenizi, Rasha El Sharkawy, Afaf Elattar, Rocio Gallego-Durán, Janett Fischer, Thomas Berg, Christopher Liddle, Manuel Romero-Gomez, Jacob George, Mohammed Eslam

Journal: EBioMedicine

PubMed ID: 34388518

Doi: 10.1016/j.ebiom.2021.103521

Products & Services: ORF cDNA Clones/MolecularCloud

N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization

Authors: Michael J Currie, Lavanyaa Manjunath, Christopher R Horne, Phillip M Rendle, Ramaswamy Subramanian, Rosmarie Friemann, Antony J Fairbanks, Andrew C Muscroft-Taylor, Rachel A North, Renwick C J Dobson

Journal: J Biol Chem

PubMed ID: 34437902

Doi: 10.1016/j.jbc.2021.101113

Products & Services: Plasmid DNA Preparation

Vestibular and Auditory Hair Cell Regeneration Following Targeted Ablation of Hair Cells With Diphtheria Toxin in Zebrafish

Authors: Erin Jimenez, Claire C Slevin, Luis Colón-Cruz, Shawn M Burgess

Journal: Front Cell Neurosci

PubMed ID: 34489643

Doi: 10.3389/fncel.2021.721950

Products & Services: PCR Cloning and Subcloning

Genome-Wide Identification, Expression and Functional Analysis Reveal the Involvement of FCS-Like Zinc Finger Gene Family in Submergence Response in Rice

Authors: Yamei Ma, Junliang Zhao, Hua Fu, Tifeng Yang, Jingfang Dong, Wu Yang, Luo Chen, Lian Zhou, Jian Wang, Bin Liu, Shaohong Zhang, David Edwards

Journal: Rice (N Y)

PubMed ID: 34417910

Doi: 10.1186/s12284-021-00519-3

Products & Services: Protein Tools

Cas9-derived peptides presented by MHC Class II that elicit proliferation of CD4 T-cells

Authors: Vijaya L Simhadri, Louis Hopkins, Joseph R McGill, Brian R Duke, Swati Mukherjee, Kate Zhang, Zuben E Sauna

Journal: Nat Commun

PubMed ID: 34429421

Doi: 10.1038/s41467-021-25414-9

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Impaired Cx43 gap junction endocytosis causes morphological and functional defects in zebrafish

Authors: Caitlin Hyland, Michael Mfarej, Giorgos Hiotis, Sabrina Lancaster, Noelle Novak, M Kathryn Iovine, Matthias M Falk

Journal: Mol Biol Cell

PubMed ID: 34379446

Doi: 10.1091/mbc.E20-12-0797

Influence of Fc modifications and IgG subclass on biodistribution of humanized antibodies targeting L1CAM

Authors: Sai Kiran Sharma, Maya Suzuki, Hong Xu, Joshua A Korsen, Zachary Samuels, Hongfen Guo, Brandon Nemieboka, Alessandra Piersigilli, Kimberly J Edwards, Nai-Kong Cheung, Jason S Lewis

Journal: J Nucl Med

PubMed ID: 34353869

Doi: 10.2967/jnumed.121.262383

Products & Services: Gene Synthesis

Author Correction: Identification, characterization and control of a sequence variant in monoclonal antibody drug product: a case study

Authors: Anushikha Thakur, Rekha Nagpal, Avik Kumar Ghosh, Deepak Gadamshetty, Sirisha Nagapattinam, Malini Subbarao, Shreshtha Rakshit, Sneha Padiyar, Suma Sreenivas, Nagaraja Govindappa, Harish V Pai, Ramakrishnan Melarkode Subbaraman

Journal: Sci Rep

PubMed ID: 34462514

Doi: 10.1038/s41598-021-96916-1

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The Aneugenicity of Ketone Bodies in Colon Epithelial Cells Is Mediated by Microtubule Hyperacetylation and Is Blocked by Resveratrol

Authors: Haruka Sudo, Akira Kubo

Journal: Int J Mol Sci

PubMed ID: 34502304

Doi: 10.3390/ijms22179397

Products & Services: Mammalian Expression

Alteration of Allergen Fold of Bos d 5 into a Hypoallergenic Vaccine for Immunotherapy of Cow's Milk Allergy

Authors: Yaqiong Cui, Yang Yu, Shuxiang Lin, Li Xu, Liuxu Li, Chunquan Cai, Huiqiang Li

Journal: Int Arch Allergy Immunol

PubMed ID: 34515139

Doi: 10.1159/000517998

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Enhanced tumor homing of pathogen-mimicking liposomes driven by R848 stimulation: A new platform for synergistic oncology therapy

Authors: Xiaobei Cheng, Pei Yu, Xiang Zhou, Jiale Zhu, Yubao Han, Chao Zhang, Lingyi Kong

Journal: Acta Pharm Sin B

PubMed ID: 35256955

Doi: 10.1016/j.apsb.2021.08.018

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Molecular Cloning and Expression Profile of Class Genes Related to Sepal Development in

Authors: Zhuoxing Liu, Dasheng Zhang, Weiwei Zhang, Lei Xiong, Qingqing Liu, Fengluan Liu, Hanchun Li, Xiangjie An, Lijie Cui, Daike Tian

Journal: Plants (Basel)

PubMed ID: 34451674

Doi: 10.3390/plants10081629

Products & Services: GenParts™ DNA Fragments

Enhanced genome editing efficiency of CRISPR PLUS: Cas9 chimeric fusion proteins

Authors: Jongjin Park, Jiyoung Yoon, Daekee Kwon, Mi-Jung Han, Sunmee Choi, Slki Park, Junghyuk Lee, Kiwook Lee, Jaehwan Lee, Seunghee Lee, Kyung-Sun Kang, Sunghwa Choe

Journal: Sci Rep

PubMed ID: 34376729

Doi: 10.1038/s41598-021-95406-8

Products & Services: Mammalian Expression

Evidence that class I glutamine amidotransferase, GAT1_21, acts as a glutaminase in roots of Arabidopsis thaliana

Authors: Shrikaar Kambhampati, Aga Pajak, Frédéric Marsolais

Journal: Plant Sci

PubMed ID: 34620437

Doi: 10.1016/j.plantsci.2021.111033

Products & Services: Proteins, Expression, Isolation and Analysis

Der p 38 Is a Bidirectional Regulator of Eosinophils and Neutrophils in Allergy

Authors: Min Hwa Hong, Ayesha Kashif, Geunyeong Kim, Beom Seok Park, Na Rae Lee, Eun Ju Yang, Ji Young Mun, Hyosun Choi, Sang-Hoon Kim, Hyun Jik Kim, Soo Jin Lee, Ji-Sook Lee, Yujin Hong, In Sik Kim

Journal: J Immunol

PubMed ID: 34462314

Doi: 10.4049/jimmunol.2001144

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Quantitative SARS-CoV-2 Spike Antibody Response in COVID-19 Patients Using Three Fully Automated Immunoassays and a Surrogate Virus Neutralization Test

Authors: Yoonjoo Kim, Ji Hyun Lee, Geon Young Ko, Ji Hyeong Ryu, Joo Hee Jang, Hyunjoo Bae, Seung-Hyo Yoo, Ae-Ran Choi, Jin Jung, Jongmin Lee, Eun-Jee Oh

Journal: Diagnostics (Basel)

PubMed ID: 34441430

Doi: 10.3390/diagnostics11081496

Products & Services: Proteins, Expression, Isolation and Analysis

Novel Host Recognition Mechanism of the K1 Capsule-Specific Phage of : Capsular Polysaccharide as the First Receptor and Lipopolysaccharide as the Secondary Receptor

Authors: Qianwen Gong, Xuhang Wang, Haosheng Huang, Yu Sun, Xinjie Qian, Feng Xue, Jianluan Ren, Jianjun Dai, Fang Tang

Journal: J Virol

PubMed ID: 34191582

Doi: 10.1128/JVI.00920-21

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Targeted and activatable nanosystem for fluorescent and optoacoustic imaging of immune-mediated inflammatory diseases and therapy via inhibiting NF-κB/NLRP3 pathways

Authors: Lihe Sun, Juan Ouyang, Zhuo Zeng, Cheng Zeng, Yunqing Ma, Fang Zeng, Shuizhu Wu

Journal: Bioact Mater

PubMed ID: 34901531

Doi: 10.1016/j.bioactmat.2021.08.010

Products & Services: Proteins, Expression, Isolation and Analysis

HIV-1 Nef interacts with the cyclin K/CDK13 complex to antagonize SERINC5 for optimal viral infectivity

Authors: Qingqing Chai, Sunan Li, Morgan K Collins, Rongrong Li, Iqbal Ahmad, Silas F Johnson, Dylan A Frabutt, Zhichang Yang, Xiaojing Shen, Liangliang Sun, Jian Hu, Judd F Hultquist, B Matija Peterlin, Yong-Hui Zheng

Journal: Cell Rep

PubMed ID: 34380030

Doi: 10.1016/j.celrep.2021.109514

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Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

Authors: Olivia Swanson, Brianna Rhodes, Avivah Wang, Shi-Mao Xia, Robert Parks, Haiyan Chen, Aja Sanzone, Melissa Cooper, Mark K Louder, Bob C Lin, Nicole A Doria-Rose, Mattia Bonsignori, Kevin O Saunders, Kevin Wiehe, Barton F Haynes, Mihai L Azoitei

Journal: Cell Rep

PubMed ID: 34407396

Doi: 10.1016/j.celrep.2021.109561

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TET3 promotes AML growth and epigenetically regulates glucose metabolism and leukemic stem cell associated pathways

Authors: Alex Jose Pulikkottil, Shiva Bamezai, Tobias Ammer, Fabian Mohr, Kristin Feder, Naidu M Vegi, Tamoghna Mandal, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Amit Sinha, Christian Buske, Vijay P S Rawat

Journal: Leukemia

PubMed ID: 34462525

Doi: 10.1038/s41375-021-01390-3

Products & Services: Stable Cell Lines

Randomized Trial of a Third Dose of mRNA-1273 Vaccine in Transplant Recipients

Authors: Victoria G Hall, Victor H Ferreira, Terrance Ku, Matthew Ierullo, Beata Majchrzak-Kita, Cecilia Chaparro, Nazia Selzner, Jeffrey Schiff, Michael McDonald, George Tomlinson, Vathany Kulasingam, Deepali Kumar, Atul Humar

Journal: N Engl J Med

PubMed ID: 34379917

Doi: 10.1056/NEJMc2111462

Products & Services: SARS-CoV-2 qRT-PCR Detection Assay

Context-Specific Function of the Engineered Peptide Domain of PHPB

Authors: R Alexander Martino, Edwin C Fluck, Jacqueline Murphy, Qiang Wang, Henry Hoff, Ruth A Pumroy, Claudia Y Lee, Joshua J Sims, Soumitra Roy, Vera Y Moiseenkova-Bell, James M Wilson

Journal: J Virol

PubMed ID: 34346767

Doi: 10.1128/JVI.01164-21

Products & Services: Recombinant Antibody Expression

Dihydrotanshinone I inhibits the growth of hepatoma cells by direct inhibition of Src

Authors: Xiao-Li Jiang, Bo Deng, Sui-Hui Deng, Min Cai, Wen-Jun Ding, Zhang-Bin Tan, Rui-Xue Chen, You-Cai Xu, Hong-Lin Xu, Shuang-Wei Zhang, Shi-Qing Zhang, Bin Liu, Jing-Zhi Zhang

Journal: Phytomedicine

PubMed ID: 34538671

Doi: 10.1016/j.phymed.2021.153705

Products & Services: Proteins, Expression, Isolation and Analysis

Efficient Dicer processing of virus-derived double-stranded RNAs and its modulation by RIG-I-like receptor LGP2

Authors: Yuqiang Zhang, Yan Xu, Yunpeng Dai, Zhe Li, Jiaxing Wang, Zhi Ye, Yanxin Ren, Hua Wang, Wan-Xiang Li, Jinfeng Lu, Shou-Wei Ding, Yang Li

Journal: PLoS Pathog

PubMed ID: 34343211

Doi: 10.1371/journal.ppat.1009790

Products & Services: Proteins, Expression, Isolation and Analysis

Multigenerational selection towards longevity changes the protective role of vitamin C against graphene oxide-induced oxidative stress in house crickets

Authors: Barbara Flasz, Marta Dziewięcka, Andrzej Kędziorski, Monika Tarnawska, Jan Augustyniak, Maria Augustyniak

Journal: Environ Pollut

PubMed ID: 34416498

Doi: 10.1016/j.envpol.2021.117996

Products & Services: Proteins, Expression, Isolation and Analysis

Structure of a Minimal α-Carboxysome-Derived Shell and Its Utility in Enzyme Stabilization

Authors: Yong Quan Tan, Samson Ali, Bo Xue, Wei Zhe Teo, Lay Hiang Ling, Maybelle Kho Go, Hong Lv, Robert C Robinson, Akihiro Narita, Wen Shan Yew

Journal: Biomacromolecules

PubMed ID: 34384019

Doi: 10.1021/acs.biomac.1c00533

Products & Services: Proteins, Expression, Isolation and Analysis

Combined 4-1BB and ICOS co-stimulation improves anti-tumor efficacy and persistence of dual anti-CD19/CD20 chimeric antigen receptor T cells

Authors: Ying Wang, Kailun Zhong, Jun Ke, Xi Chen, Yi Chen, Wangyun Shu, Chunhuan Chen, Shan Hu, Xiaoke Sun, Haibin Huang, Chong Luo, Lifang Liu, Jiaming Yang, Yongke Zhang, Huijun Zhi

Journal: Cytotherapy

PubMed ID: 33863641

Doi: 10.1016/j.jcyt.2021.02.117

Products & Services: Proteins, Expression, Isolation and Analysis

Novel Glutamate-Putrescine Ligase Activity in : A New Function for Gene

Authors: Verónica Rodríguez-Herrero, Arnau Peris, Mónica Camacho, Vanesa Bautista, Julia Esclapez, María-José Bonete

Journal: Biomolecules

PubMed ID: 34439822

Doi: 10.3390/biom11081156

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Unbiased proteomic mapping of the LINE-1 promoter using CRISPR Cas9

Authors: Erica M Briggs, Paolo Mita, Xiaoji Sun, Susan Ha, Nikita Vasilyev, Zev R Leopold, Evgeny Nudler, Jef D Boeke, Susan K Logan

Journal: Mob DNA

PubMed ID: 34425899

Doi: 10.1186/s13100-021-00249-9

Products & Services: Plasmid DNA Preparation

Longitudinal Assessment of Cytokine Expression and Plasminogen Activation in Hantavirus Cardiopulmonary Syndrome Reveals Immune Regulatory Dysfunction in End-Stage Disease

Authors: Peter Simons, Yan Guo, Virginie Bondu, Susan L Tigert, Michelle Harkins, Samuel Goodfellow, Cana Tompkins, Devon Chabot-Richards, Xuexian O Yang, Laura Gonzalez Bosc, Steven Bradfute, Daniel A Lawrence, Tione Buranda

Journal: Viruses

PubMed ID: 34452463

Doi: 10.3390/v13081597

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Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles

Authors: Zekun Mu, Kevin Wiehe, Kevin O Saunders, Rory Henderson, Derek W Cain, Robert Parks, Diana Martik, Katayoun Mansouri, Robert J Edwards, Amanda Newman, Xiaozhi Lu, Shi-Mao Xia, Mattia Bonsignori, David Montefiori, Qifeng Han, Sravani Venkatayogi, Tyler Evangelous, Yunfei Wang, Wes Rountree, Ying Tam, Christopher Barbosa, S Munir Alam, Wilton B Williams, Norbert Pardi, Drew Weissman, Barton F Haynes

Journal: biorxiv

PubMed ID: 34401876

Doi: 10.1101/2021.08.09.455714

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A truncated glycoprotein G vaccine formulated with Advax-CpG adjuvant provides protection of mice against genital herpes simplex virus 2 infection

Authors: Staffan Görander, Yoshikazu Honda-Okubo, Malin Bäckström, Jeremy Baldwin, Tomas Bergström, Nikolai Petrovsky, Jan-Åke Liljeqvist

Journal: Vaccine

PubMed ID: 34456075

Doi: 10.1016/j.vaccine.2021.08.050

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DNA-guided photoactivatable probe-based chemical proteomics reveals the reader protein of mRNA methylation

Authors: Yepei Huang, Xue Bai, Zhenchang Guo, Hanyang Dong, Yun Fu, Hui Zhang, Guijin Zhai, Shanshan Tian, Ye Wang, Kai Zhang

Journal: iScience

PubMed ID: 34553132

Doi: 10.1016/j.isci.2021.103046

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Interaction of Antimicrobial Peptide Ponericin W1, Thanatin, and Mastatopara-S with Genomic DNA

Authors: Hongyan Zhang, Sha Liu, Xindan Li, Wenjun Wang, Lili Deng, Kaifang Zeng

Journal: Foods

PubMed ID: 34441696

Doi: 10.3390/foods10081919

Products & Services: Peptide Tools

Optimization of antigen-specific CD8 T cell activation conditions for infectious diseases including COVID-19

Authors: Chanchan Xiao, Congling Qiu, Jieping Deng, Jiezhou Ye, Lijuan Gao, Jun Su, Oscar Junhong Luo, Pengcheng Wang, Guobing Chen

Journal: STAR Protoc

PubMed ID: 34414379

Doi: 10.1016/j.xpro.2021.100789

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Dual concentration-dependent effect of ascorbic acid on PAP(248-286) amyloid formation and SEVI-mediated HIV infection

Authors: Satabdee Mohapatra, Guru Krishna Kumar Viswanathan, Lukas Wettstein, Elad Arad, Ashim Paul, Vijay Kumar, Raz Jelinek, Jan Münch, Daniel Segal

Journal: RSC Chem Biol

PubMed ID: 34704058

Doi: 10.1039/d1cb00084e

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Targeted genetic screening in bacteria with a Cas12k-guided transposase

Authors: Weizhong Chen, Ze-Hui Ren, Na Tang, Guoshi Chai, Hongyuan Zhang, Yifei Zhang, Jiacheng Ma, Zhaowei Wu, Xia Shen, Xingxu Huang, Guan-Zheng Luo, Quanjiang Ji

Journal: Cell Rep

PubMed ID: 34469724

Doi: 10.1016/j.celrep.2021.109635

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Vaccination against the Protozoan Parasite Primes the Activation of Toll-like Receptors in Turkeys and Chickens Determined by a Set of Newly Developed Multiplex RT-qPCRs

Authors: Taniya Mitra, Beatrice Bramberger, Ivana Bilic, Michael Hess, Dieter Liebhart

Journal: Vaccines (Basel)

PubMed ID: 34579197

Doi: 10.3390/vaccines9090960

Products & Services: ORF cDNA Clones/MolecularCloud

Downregulation of miR-1-3p expression inhibits the hypertrophy and mineralization of chondrocytes in DDH

Authors: Rui Ding, Xijuan Liu, Jian Zhang, Jinghong Yuan, Sikuan Zheng, Xigao Cheng, Jingyu Jia

Journal: J Orthop Surg Res

PubMed ID: 34407854

Doi: 10.1186/s13018-021-02666-1

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Mapping human calreticulin regions important for structural stability

Authors: Evaldas Čiplys, Tautvydas Paškevičius, Eimantas Žitkus, Juras Bielskis, Raimundas Ražanskas, Tomas Šneideris, Vytautas Smirnovas, Algirdas Kaupinis, David J Tester, Michael J Ackerman, Peter Højrup, Marek Michalak, Gunnar Houen, Rimantas Slibinskas

Journal: Biochim Biophys Acta Proteins Proteom

PubMed ID: 34358706

Doi: 10.1016/j.bbapap.2021.140710

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Inhibition of Border Disease Virus Replication With Lentivirus-Mediated shRNAs

Authors: Mohammad Javad Hajihasani Arani, Azam Mokhtari, Behnaz Saffar, Leila Asadi Samani

Journal: Front Vet Sci

PubMed ID: 34447803

Doi: 10.3389/fvets.2021.708591

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Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells

Authors: Konrad Klockmeier, Eduardo Silva Ramos, Tamás Raskó, Adrián Martí Pastor, Erich E Wanker

Journal: J Mol Biol

PubMed ID: 34364876

Doi: 10.1016/j.jmb.2021.167184

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Pan-Sarbecovirus Neutralizing Antibodies in BNT162b2-Immunized SARS-CoV-1 Survivors

Authors: Chee-Wah Tan, Wan-Ni Chia, Barnaby E Young, Feng Zhu, Beng-Lee Lim, Wan-Rong Sia, Tun-Linn Thein, Mark I-C Chen, Yee-Sin Leo, David C Lye, Lin-Fa Wang

Journal: N Engl J Med

PubMed ID: 34407341

Doi: 10.1056/NEJMoa2108453

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Early warning and rapid public health response to prevent COVID-19 outbreaks in long-term care facilities (LTCF) by monitoring SARS-CoV-2 RNA in LTCF site-specific sewage samples and assessment of antibodies response in this population: prospective study protocol

Authors: Bonita E Lee, Christopher Sikora, Douglas Faulder, Eleanor Risling, Lorie A Little, Yuanyuan Qiu, Tiejun Gao, Ross Bulat, Stephen Craik, Steve E Hrudey, Arto Ohinmaa, Carole A Estabrooks, Anne-Claude Gingras, Carmen Charlton, John Kim, Heidi Wood, Alyssia Robinson, Jamil N Kanji, Nathan Zelyas, Sheila F O'Brien, Steven Drews, Xiao-Li Pang

Journal: BMJ Open

PubMed ID: 34417219

Doi: 10.1136/bmjopen-2021-052282

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Influenza Virus-like Particle (VLP) Vaccines Expressing the SARS-CoV-2 S Glycoprotein, S1, or S2 Domains

Authors: Ki-Back Chu, Hae-Ji Kang, Keon-Woong Yoon, Hae-Ahm Lee, Eun-Kyung Moon, Beom-Ku Han, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 34452044

Doi: 10.3390/vaccines9080920

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Metabolic Engineering of BD16 for Heterologous Expression of Synthetic Gene Cassette and L-Alanine Production in the Recombinant Strain Using Fed-Batch Fermentation

Authors: Anshula Sharma, Masafumi Noda, Masanori Sugiyama, Baljinder Kaur, Ajaz Ahmad

Journal: Foods

PubMed ID: 34441741

Doi: 10.3390/foods10081964

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miRNA-451 regulates the NF-κB signaling pathway by targeting IKKβ to inhibit glioma cell growth

Authors: Yang Nan, Liyun Guo, Yingwei Zhen, Le Wang, Bingcheng Ren, Xingjie Chen, Yalin Lu, Kai Yu, Yue Zhong, Qiang Huang

Journal: Cell Cycle

PubMed ID: 34463194

Doi: 10.1080/15384101.2021.1969496

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Litopenaeus vannamei peroxiredoxin 2-like is involved in WSSV infection by interaction with wsv089 and VP26

Authors: Xing-Chao Ren, Xiao-Ping Liu, Qing-Hui Liu

Journal: Dev Comp Immunol

PubMed ID: 34450129

Doi: 10.1016/j.dci.2021.104243

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A continuous spectrophotometric assay for glutathione-independent glyoxalases

Authors: Tomiris Mulikova, Zhanibek Bekkhozhin, Aizat Abdirassil, Darkhan Utepbergenov

Journal: Anal Biochem

PubMed ID: 34391725

Doi: 10.1016/j.ab.2021.114317

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Radiation-Induced Phosphorylation of a Prion-Like Domain Regulates Transformation by FUS-CHOP

Authors: Mark Chen, Joseph P Foster, Ian C Lock, Nathan H Leisenring, Andrea R Daniel, Warren Floyd, Eric Xu, Ian J Davis, David G Kirsch

Journal: Cancer Res

PubMed ID: 34385184

Doi: 10.1158/0008-5472.CAN-20-1497

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An ester bond underlies the mechanical strength of a pathogen surface protein

Authors: Hai Lei, Quan Ma, Wenfei Li, Jing Wen, Haibo Ma, Meng Qin, Wei Wang, Yi Cao

Journal: Nat Commun

PubMed ID: 34426584

Doi: 10.1038/s41467-021-25425-6

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Meet the authors: Michael Ranes and Sebastian Guettler

Authors:

Journal: Mol Cell

PubMed ID: 34416135

Doi: 10.1016/j.molcel.2021.08.002

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Dynamics of SARS-CoV-2 Spike Proteins in Cell Entry: Control Elements in the Amino-Terminal Domains

Authors: Enya Qing, Tom Kicmal, Binod Kumar, Grant M Hawkins, Emily Timm, Stanley Perlman, Tom Gallagher

Journal: MBio

PubMed ID: 34340537

Doi: 10.1128/mBio.01590-21

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Deep survey for designing a vaccine against SARS-CoV-2 and its new mutations

Authors: Bahareh Vakili, Ashkan Bagheri, Manica Negahdaripour

Journal: Biologia (Bratisl)

PubMed ID: 34421121

Doi: 10.1007/s11756-021-00866-y

Products & Services: Codon Optimization

Compact RNA editors with small Cas13 proteins

Authors: Soumya Kannan, Han Altae-Tran, Xin Jin, Victoria J Madigan, Rachel Oshiro, Kira S Makarova, Eugene V Koonin, Feng Zhang

Journal: Nat Biotechnol

PubMed ID: 34462587

Doi: 10.1038/s41587-021-01030-2

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Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor

Authors: Shanshan Ma, Yan Chen, Antao Dai, Wanchao Yin, Jia Guo, Dehua Yang, Fulai Zhou, Yi Jiang, Ming-Wei Wang, H Eric Xu

Journal: Cell Res

PubMed ID: 34453129

Doi: 10.1038/s41422-021-00557-y

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Structure of the Human Cholesterol Transporter ABCG1

Authors: Liga Skarda, Julia Kowal, Kaspar P Locher

Journal: J Mol Biol

PubMed ID: 34461069

Doi: 10.1016/j.jmb.2021.167218

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Development of a chimeric protein based on a proteomic approach for the serological diagnosis of human tegumentary leishmaniasis

Authors: Guilherme Caetano Garcia, Ana Maria Ravena Severino Carvalho, Mariana Costa Duarte, Matheus Fernandes Costa E Silva, Fernanda Alvarenga Cardoso Medeiros, Eduardo Antonio Ferraz Coelho, Dênia Monteiro de Moura Franco, Denise Utsch Gonçalves, Tiago Antônio de Oliveira Mendes, Daniel Menezes-Souza

Journal: Appl Microbiol Biotechnol

PubMed ID: 34432132

Doi: 10.1007/s00253-021-11518-1

Products & Services: Bacterial Expression

Optimising PHBV biopolymer production in haloarchaea via CRISPRi-mediated redirection of carbon flux

Authors: Lin Lin, Junyu Chen, Ruchira Mitra, Quanxiu Gao, Feiyue Cheng, Tong Xu, Zhenqiang Zuo, Hua Xiang, Jing Han

Journal: Commun Biol

PubMed ID: 34433872

Doi: 10.1038/s42003-021-02541-z

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RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers

Authors: Hannah G Abraham, Peter J Ulintz, Laura Goo, Joel A Yates, Andrew C Little, Liwei Bao, Zhifen Wu, Sofia D Merajver

Journal: Front Oncol

PubMed ID: 34513691

Doi: 10.3389/fonc.2021.712041

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Expressing Type I Interferon From Atlantic Salmon Enhances the Innate Antiviral Immune Response and

Authors: Carlos Muñoz, Josue González-Lorca, Mick Parra, Sarita Soto, Natalia Valdes, Ana María Sandino, Rodrigo Vargas, Alex González, Mario Tello

Journal: Front Immunol

PubMed ID: 34475871

Doi: 10.3389/fimmu.2021.696781

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Identifying the Basis for VirS/VirR Two-Component Regulatory System Control of Clostridium perfringens Beta-Toxin Production

Authors: Iman Mehdizadeh Gohari, Jihong Li, Bruce A McClane

Journal: J Bacteriol

PubMed ID: 34228498

Doi: 10.1128/JB.00279-21

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A novel RNA detection technique for point-of-care identification of pathogens

Authors: Mekbib Astatke, Olivia Tiburzi, Amy Connolly

Journal: J Immunoassay Immunochem

PubMed ID: 34355634

Doi: 10.1080/15321819.2021.1955380

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Genome editing with CRISPR/Cas9 in Pinus radiata (D. Don)

Authors: Charleson Poovaiah, Lorelle Phillips, Barbara Geddes, Cathie Reeves, Mathias Sorieul and Glenn Thorlby

Journal: BMC Plant Biology

PubMed ID: 34376154

Doi: 10.1186/s12870-021-03143-x

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GRB2 enforces homology-directed repair initiation by MRE11.

Authors: Zu Ye, Shengfeng Xu, Yin Shi, Albino Bacolla, Aleem Syed, Davide Moiani, Chi-Lin Tsai, Qiang Shen, Guang Peng, Paul G Leonard, Darin E Jones, Bin Wang, John A Tainer, Zamal Ahmed

Journal: Sci Adv

Doi: 10.1126/sciadv.abe9254

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Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor

Authors: Yue Wang, Shimeng Guo, Youwen Zhuang, Ying Yun, Peiyu Xu, Xinheng He, Jia Guo, Wanchao Yin, H Eric Xu, Xin Xie, Yi Jiang

Journal: Nat Commun.

PubMed ID: 34417468

Doi: 10.1038/s41467-021-25364-2

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An EZH2-dependent transcriptional complex promotes aberrant epithelial remodelling after injury

Authors: Huy Q Le, Matthew A Hill, Ines Kollak, Martina Keck, Victoria Schroeder, Johannes Wirth, Wioletta Skronska-Wasek, Eva Schruf, Benjamin Strobel, Heiko Stahl, Franziska E Herrmann, Alexandre R Campos, Jun Li, Karsten Quast, Dagmar Knebel, Coralie Viollet, Matthew J Thomas, David Lamb, James P Garnett

Journal: EMBO Rep

PubMed ID: 34224201

Doi: 10.15252/embr.202152785

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Comprehensive Proteome and Lysine Acetylome Analysis Reveals the Widespread Involvement of Acetylation in Cold Resistance of Pepper ( L)

Authors: Zhoubin Liu, Jingshuang Song, Wu Miao, Bozhi Yang, Zhuqing Zhang, Wenchao Chen, Fangjun Tan, Huan Suo, Xiongze Dai, Xuexiao Zou, Lijun Ou

Journal: Front Plant Sci

PubMed ID: 34512705

Doi: 10.3389/fpls.2021.730489

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Human Cystathionine γ-Lyase Is Inhibited by -Nitrosation: A New Crosstalk Mechanism between NO and HS

Authors: Dalila G F Fernandes, João Nunes, Catarina S Tomé, Karim Zuhra, João M F Costa, Alexandra M M Antunes, Alessandro Giuffrè, João B Vicente

Journal: Antioxidants (Basel)

PubMed ID: 34573023

Doi: 10.3390/antiox10091391

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DSB-3 reveals conservation and divergence among protein complexes promoting meiotic double-strand breaks

Authors: Albert W Hinman, Hsin-Yi Yeh, Baptiste Roelens, Kei Yamaya, Alexander Woglar, Henri-Marc G Bourbon, Peter Chi, Anne M Villeneuve

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34389685

Doi: 10.1073/pnas.2109306118

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Immune responses in COVID-19 respiratory tract and blood reveal mechanisms of disease severity

Authors: Wuji Zhang, Brendon Chua, Kevin Selva, Lukasz Kedzierski, Thomas Ashhurst, Ebene Haycroft, Suzanne Shoffner, Luca Hensen, David Boyd, Fiona James, Effie Mouhtouris, Jason Kwong, Kyra Chua, George Drewett, Ana Copaescu, Julie Dobson, Louise Rowntree, Jennifer Habel, Lilith Allen, Hui-Fern Koay, Jessica Neil, Matthew Gartner, Christina Lee, Patiyan Andersson, Torsten Seemann, Norelle Sherry, Fatima Amanat, Florian Krammer, Sarah Londrigan, Linda Wakim, Nicholas King, Dale Godfrey, Laura Mackay, Paul Thomas, Suellen Nicholson, Kelly Arnold, Amy Chung, Natasha Holmes, Olivia Smibert, Jason Trubiano, Claire Gordon, Thi Nguyen, Katherine Kedzierska

Journal: Res Sq

PubMed ID: 34462740

Doi: 10.21203/rs.3.rs-802084/v1

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SARS-CoV-2 Isolates Show Impaired Replication in Human Immune Cells but Differential Ability to Replicate and Induce Innate Immunity in Lung Epithelial Cells

Authors: Miao Jiang, Pekka Kolehmainen, Laura Kakkola, Sari Maljanen, Krister Melén, Teemu Smura, Ilkka Julkunen, Pamela Österlund

Journal: Microbiol Spectr

PubMed ID: 34378952

Doi: 10.1128/Spectrum.00774-21

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A newly characterized malaria antigen on erythrocyte and merozoite surfaces induces parasite inhibitory antibodies

Authors: Ian C Michelow, Sangshin Park, Shu-Whei Tsai, Bonnie Rayta, Charisse Flerida A Pasaje, Sara Nelson, Angela M Early, Anne P Frosch, George Ayodo, Dipak K Raj, Christina E Nixon, Christian P Nixon, Sunthorn Pond-Tor, Jennifer F Friedman, Michal Fried, Patrick E Duffy, Karine G Le Roch, Jacquin C Niles, Jonathan D Kurtis

Journal: J Exp Med

PubMed ID: 34342640

Doi: 10.1084/jem.20200170

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Interaction of Human C5a with the Major Peptide Fragments of C5aR1: Direct Evidence in Support of "Two-Site" Binding Paradigm

Authors: Aurosikha Das, Lalita Mohan Behera, Soumendra Rana

Journal: ACS Omega

PubMed ID: 34514259

Doi: 10.1021/acsomega.1c03400

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compensates for in mice in the amino-terminal acetylation pathway

Authors: Hyae Yon Kweon, Mi-Ni Lee, Max Dorfel, Seungwoon Seo, Leah Gottlieb, Thomas PaPazyan, Nina McTiernan, Rasmus Ree, David Bolton, Andrew Garcia, Michael Flory, Jonathan Crain, Alison Sebold, Scott Lyons, Ahmed Ismail, Elaine Marchi, Seong-Keun Sonn, Se-Jin Jeong, Sejin Jeon, Shinyeong Ju, Simon J Conway, Taesoo Kim, Hyun-Seok Kim, Cheolju Lee, Tae-Young Roh, Thomas Arnesen, Ronen Marmorstein, Goo Taeg Oh, Gholson J Lyon

Journal: Elife

PubMed ID: 34355692

Doi: 10.7554/eLife.65952

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Conformational equilibria in allosteric control of Hsp70 chaperones

Authors: Wei Wang, Qinglian Liu, Qun Liu, Wayne A Hendrickson

Journal: Mol Cell

PubMed ID: 34453889

Doi: 10.1016/j.molcel.2021.07.039

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Activated Alpha 2-Macroglobulin Is a Novel Mediator of Mesangial Cell Profibrotic Signaling in Diabetic Kidney Disease

Authors: Jackie Trink, Renzhong Li, Yaseelan Palarasah, Stéphan Troyanov, Thomas E Andersen, Johannes J Sidelmann, Mark D Inman, Salvatore V Pizzo, Bo Gao, Joan C Krepinsky

Journal: Biomedicines

PubMed ID: 34572299

Doi: 10.3390/biomedicines9091112

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Long Non-Coding RNA TRG-AS1 Promoted Proliferation and Invasion of Lung Cancer Cells Through the miR-224-5p/SMAD4 Axis

Authors: Mengyan Zhang, Weiguo Zhu, Mansour Haeryfar, Sumei Jiang, Xiang Jiang, Wei Chen, Jiancheng Li

Journal: Onco Targets Ther

PubMed ID: 34408438

Doi: 10.2147/OTT.S297336

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Objective Measurements Associated with the Preferred Eating Qualities of Fermented Salamis

Authors: Jihan Kim, Scott Knowles, Raise Ahmad, Li Day

Journal: Foods

PubMed ID: 34574113

Doi: 10.3390/foods10092003

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Ion Transport Activity Assay for Microbial Rhodopsin Expressed in Cells

Authors: Masae Konno, Keiichi Inoue, Hideki Kandori

Journal: Bio Protoc

PubMed ID: 34458409

Doi: 10.21769/BioProtoc.4115

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Insertion of prpoD_rpoS fragment enhances expression of recombinant protein by dps auto-inducible promoter in Escherichia coli

Authors: Dina Mulyanti, Sundani Nurono Soewandhi, Catur Riani

Journal: Mol Biol Rep

PubMed ID: 34342815

Doi: 10.1007/s11033-021-06562-z

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Hydrolysis of a second Asp-Pro site at the N-terminus of NOTCH3 in inherited vascular dementia

Authors: Xiaojie Zhang, Soo Jung Lee, Michael M Wang

Journal: Sci Rep

PubMed ID: 34446744

Doi: 10.1038/s41598-021-96679-9

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A micro-peptide encoded by HOXB-AS3 promotes the proliferation and viability of oral squamous cell carcinoma cell lines by directly binding with IGF2BP2 to stabilize c-Myc

Authors: Fei Leng, Yan-Yu Miu, Yi Zhang, Hao Luo, Xiao-Li Lu, Hui Cheng, Zhi-Guo Zheng

Journal: Oncol Lett

PubMed ID: 34457052

Doi: 10.3892/ol.2021.12958

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Platelet-derived growth factor (PDGF)-BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase

Authors: Huan Chen, Yan Teng, Xingmin Chen, Zhihao Liu, Fan Geng, Yanzhuo Liu, Haisong Jiang, Ziyan Wang, Lu Yang

Journal: CNS Neurosci Ther

PubMed ID: 34346167

Doi: 10.1111/cns.13708

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Evidence for UV-green dichromacy in the basal hymenopteran Sirex noctilio (Siricidae)

Authors: Quentin Guignard, Johannes Spaethe, Bernard Slippers, Martin Strube-Bloss, Jeremy D Allison

Journal: Sci Rep

PubMed ID: 34341410

Doi: 10.1038/s41598-021-95107-2

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Engineering analysis of multienzyme cascade reactions for 3'-sialyllactose synthesis

Authors: Sabine Schelch, Manuel Eibinger, Stefanie Gross Belduma, Barbara Petschacher, Jürgen Kuballa, Bernd Nidetzky

Journal: Biotechnol Bioeng

PubMed ID: 34289079

Doi: 10.1002/bit.27898

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Does Differential Receptor Distribution Underlie Variable Responses to a Neuropeptide in the Lobster Cardiac System?

Authors: Audrey J Muscato, Patrick Walsh, Sovannarath Pong, Alixander Pupo, Roni J Gross, Andrew E Christie, J Joe Hull, Patsy S Dickinson

Journal: Int J Mol Sci

PubMed ID: 34445418

Doi: 10.3390/ijms22168703

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Genome-Wide Identification and Characterization of KNOTTED-Like Homeobox (KNOX) Homologs in Garlic ( L) and Their Expression Profilings Responding to Exogenous Cytokinin and Gibberellin

Authors: Siyu Zhang, Yupeng Pan, Chengchen Zhi, Yujie Zheng, Xi'ao Wang, Xiaxia Li, Zhihui Cheng

Journal: Int J Mol Sci

PubMed ID: 34502163

Doi: 10.3390/ijms22179237

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Inhibition of NOD1 Attenuates Neonatal Hypoxia-Ischemia Induced Long-Term Cognitive Impairments in Mice Through Modulation of Autophagy-Related Proteins

Authors: Fang Liu, Mingyu Shao, Feng Xu, Fang Rong

Journal: Neuropsychiatr Dis Treat

PubMed ID: 34421301

Doi: 10.2147/NDT.S314884

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Rapid CRISPR/Cas9 Editing of Genotype IX African Swine Fever Virus Circulating in Eastern and Central Africa

Authors: Hussein M Abkallo, Nicholas Svitek, Bernard Oduor, Elias Awino, Sonal P Henson, Samuel O Oyola, Stephen Mwalimu, Nacrya Assad-Garcia, Walter Fuchs, Sanjay Vashee, Lucilla Steinaa

Journal: Front Genet

PubMed ID: 34527025

Doi: 10.3389/fgene.2021.733674

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Three-layered control of mRNA poly(A) tail synthesis in

Authors: Matti Turtola, M Cemre Manav, Ananthanarayanan Kumar, Agnieszka Tudek, Seweryn Mroczek, Paweł S Krawczyk, Andrzej Dziembowski, Manfred Schmid, Lori A Passmore, Ana Casañal, Torben Heick Jensen

Journal: Genes Dev

PubMed ID: 34385261

Doi: 10.1101/gad.348634.121

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Inhibition of Three Citrus Pathogenic Fungi by Peptide PAF56 Involves Cell Membrane Damage

Authors: Wenjun Wang, Guirong Feng, Xindan Li, Changqing Ruan, Jian Ming, Kaifang Zeng

Journal: Foods

PubMed ID: 34574141

Doi: 10.3390/foods10092031

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CRISPR-mediated Labeling of Cells in Chick Embryos Based on Selectively Expressed Genes

Authors: Masahito Yamagata, Joshua R Sanes

Journal: Bio Protoc

PubMed ID: 34458399

Doi: 10.21769/BioProtoc.4105

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Butyryl/Caproyl-CoA:Acetate CoA-transferase: cloning, expression and characterization of the key enzyme involved in medium-chain fatty acid biosynthesis

Authors: Qingzhuoma Yang, Shengtao Guo, Qi Lu, Yong Tao, Decong Zheng, Qinmao Zhou, Jun Liu

Journal: Biosci Rep

PubMed ID: 34338280

Doi: 10.1042/BSR20211135

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Sulfated glycosaminoglycans and low-density lipoprotein receptor mediate the cellular entry of Clostridium novyi alpha-toxin

Authors: Yao Zhou, Diyin Li, Jianhua Luo, Aizhong Chen, Xingxing Li, Zhenrui Pan, Li Wan, Liuqing He, Danyang Li, Yanyan Li , Min Dong, Liang Tao

Journal: Cell Res

PubMed ID: 33972749

Doi: 10.1038/s41422-021-00510-z

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Secreted Expression of mRNA-Encoded Truncated ACE2 Variants for SARS-CoV-2 via Lipid-Like Nanoassemblies

Authors: Min Li, Sanpeng Li, Yixuan Huang, Haixia Chen, Songya Zhang, Zhicheng Zhang, Weigang Wu, Xiaobin Zeng, Boping Zhou, Bin Li

Journal: Adv Mater

PubMed ID: 34278613

Doi: 10.1002/adma.202101707

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