客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 90/514 每页显示数量

CG Dinucleotide Removal in Bioluminescent and Fluorescent Reporters Improves HIV-1 Replication and Reporter Gene Expression for Dual Imaging in Humanized Mice

Authors: Chandra N Roy, Mariana A Benitez Moreno, Chris Kline, Zandrea Ambrose

Journal: J Virol

PubMed ID: 34232063

Doi: 10.1128/JVI.00449-21

Products & Services: Gene Synthesis

Hydroxychloroquine Induces Apoptosis in Cholangiocarcinoma Reactive Oxygen Species Accumulation Induced by Autophagy Inhibition

Authors: Jiaqi Chen, Qiaoya Pan, Yang Bai, Xuepeng Chen, Yi Zhou

Journal: Front Mol Biosci

PubMed ID: 34568426

Doi: 10.3389/fmolb.2021.720370

Products & Services: Gene Synthesis

Corrigendum: Reductive Power Generated by Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis

Authors: Thabatta L S A Rosa, Maria Angela M Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A Silva, Christine R Montague, Tianao Yuan, Julio J Amaral, Georgia C Atella, Patrícia S Rosa, Katherine A Mattos, Brian C VanderVen, Ramanuj Lahiri, Nicole S Sampson, Patrick J Brennan, John T Belisle, Maria Cristina V Pessolani, Marcia Berrêdo-Pinho

Journal: Front Cell Infect Microbiol

PubMed ID: 34650934

Doi: 10.3389/fcimb.2021.765326

Products & Services: Gene Synthesis

A Novel TLR4-Binding Domain of Peroxiredoxin From Triggers NLRP3 Inflammasome Activation in Macrophages

Authors: Xia Li, Meng Feng, Yanqing Zhao, Yuhan Zhang, Ruixue Zhou, Hang Zhou, Zhen Pang, Hiroshi Tachibana, Xunjia Cheng

Journal: Front Immunol

PubMed ID: 34659265

Doi: 10.3389/fimmu.2021.758451

Products & Services: Custom DNA/RNA Oligos

Two novel SARS-CoV-2 surrogate virus neutralization assays are suitable for assessing successful immunization with mRNA-1273

Authors: Alexander Krüttgen, Maike Lauen, Hanna Klingel, Matthias Imöhl, Michael Kleines

Journal: J Virol Methods

PubMed ID: 34563583

Doi: 10.1016/j.jviromet.2021.114297

Products & Services: SARS-CoV-2 qRT-PCR Detection Assay

Advancements in detection of SARS-CoV-2 infection for confronting COVID-19 pandemics

Authors: Yuan Zhou, Li Zhang, You-Hua Xie, Jian Wu

Journal: Lab Invest

PubMed ID: 34497366

Doi: 10.1038/s41374-021-00663-w

Products & Services: SARS-CoV-2 qRT-PCR Detection Assay

Ablation of PDE4B protects from Pseudomonas aeruginosa-induced acute lung injury in mice by ameliorating the cytostorm and associated hypothermia

Authors: Lina Abou Saleh, Abigail Boyd, Ileana V Aragon, Anna Koloteva, Domenico Spadafora, Wadad Mneimneh, Robert A Barrington, Wito Richter

Journal: FASEB J

PubMed ID: 34383981

Doi: 10.1096/fj.202100495R

Products & Services: Recombinant Antibody Expression

Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia

Authors: Samoil Sekulovski, Pascal Devant, Silvia Panizza, Tasos Gogakos, Anda Pitiriciu, Katharina Heitmeier, Ewan Phillip Ramsay, Marie Barth, Carla Schmidt, Thomas Tuschl, Frank Baas, Stefan Weitzer, Javier Martinez, Simon Trowitzsch

Journal: Nat Commun

PubMed ID: 34584079

Doi: 10.1038/s41467-021-25870-3

Products & Services: Recombinant Antibody Expression

Effect of ORF7 of SARS-CoV-2 on the Chemotaxis of Monocytes and Neutrophils In Vitro

Authors: Gang Wang, Jun Guan, Guojun Li, Fengtian Wu, Qin Yang, Chunhong Huang, Junwei Shao, Lichen Xu, Zixuan Guo, Qihui Zhou, Haihong Zhu, Zhi Chen

Journal: Dis Markers

PubMed ID: 34603560

Doi: 10.1155/2021/6803510

Products & Services: Proteins, Expression, Isolation and Analysis

Fabrication of a Silk Sericin Hydrogel System Delivering Human Lactoferrin Using Genetically Engineered Silk with Improved Bioavailability to Alleviate Chemotherapy-Induced Immunosuppression

Authors: Sheng Xu, Huanhuan Tan, Qianqian Yang, Riyuan Wang, Chi Tian, Yanting Ji, Ping Zhao, Qingyou Xia, Feng Wang

Journal: ACS Appl Mater Interfaces

PubMed ID: 34525798

Doi: 10.1021/acsami.1c08409

Products & Services: Proteins, Expression, Isolation and Analysis

Distinct endocytosis and immune activation of poly(lactic-co-glycolic) acid nanoparticles prepared by single- and double-emulsion evaporation

Authors: Lennart Pusch, Regine Brox, Karl Scheuer, Tadahiro Yokosawa, Mingjian Wu, Benjamin Apeleo Zubiri, Erdmann Spiecker, Klaus D Jandt, Dagmar Fischer, Holger Hackstein

Journal: Nanomedicine (Lond)

PubMed ID: 34523349

Doi: 10.2217/nnm-2021-0022

Products & Services: Proteins, Expression, Isolation and Analysis

Discovery of an Heparin-Binding Epidermal Growth Factor Domain Antibody from a Phage Library and Analysis of Its Inhibitory Effects in SKOV3 Cells

Authors: Peng Lü, Songlin Qiu, Ye Pan, Shenyan Shi, Qian Yu, Feng Yu, Lianjun Miao, Huiying Wang, Keping Chen

Journal: Cancer Biother Radiopharm

PubMed ID: 34529926

Doi: 10.1089/cbr.2021.0123

Products & Services: Proteins, Expression, Isolation and Analysis

METTL3-mediated mA RNA methylation promotes the anti-tumour immunity of natural killer cells

Authors: Hao Song, Jiaxi Song, Ming Cheng, Meijuan Zheng, Tian Wang, Sha Tian, Richard A Flavell, Shu Zhu, Hua-Bing Li, Chen Ding, Haiming Wei, Rui Sun, Hui Peng, Zhigang Tian

Journal: Nat Commun

PubMed ID: 34535671

Doi: 10.1038/s41467-021-25803-0

Products & Services: Proteins, Expression, Isolation and Analysis

Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43

Authors: Takashi Shiroyama, Kouji Fukuyama, Motohiro Okada

Journal: Int J Mol Sci

PubMed ID: 34576176

Doi: 10.3390/ijms221810013

Products & Services: Proteins, Expression, Isolation and Analysis

The molecular basis of extensively drug-resistant Salmonella Typhi isolates from pediatric septicemia patients

Authors: Chanmi Kim, Iqra Latif, Durga P Neupane, Gi Young Lee, Ryan S Kwon, Alia Batool, Qasim Ahmed, Muhammad Usman Qamar, Jeongmin Song

Journal: PLoS ONE

PubMed ID: 34582469

Doi: 10.1371/journal.pone.0257744

Products & Services: PCR and Cloning

Identification of BvgA-Dependent and BvgA-Independent Small RNAs (sRNAs) in Bordetella pertussis Using the Prokaryotic sRNA Prediction Toolkit ANNOgesic

Authors: Kyung Moon, Minji Sim, Chin-Hsien Tai, Kyungyoon Yoo, Charlotte Merzbacher, Sung-Huan Yu, David D Kim, Jaehyun Lee, Konrad U Förstner, Qing Chen, Scott Stibitz, Leslie G Knipling, Deborah M Hinton

Journal: Microbiol Spectr

PubMed ID: 34550019

Doi: 10.1128/Spectrum.00044-21

Products & Services: GenParts™ DNA Fragments

Genome-Wide CRISPR Screen Identifies RACK1 as a Critical Host Factor for Flavivirus Replication

Authors: Byron Shue, Abhilash I Chiramel, Berati Cerikan, Thu-Hien To, Sonja Frölich, Stephen M Pederson, Emily N Kirby, Nicholas S Eyre, Ralf F W Bartenschlager, Sonja M Best, Michael R Beard

Journal: J Virol

PubMed ID: 34586867

Doi: 10.1128/JVI.00596-21

Products & Services: Proteins, Expression, Isolation and Analysis

Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response

Authors: Kishu Ranjan, Matija Hedl, Saloni Sinha, Xuchen Zhang, Clara Abraham

Journal: J Clin Invest

PubMed ID: 34623328

Doi: 10.1172/JCI145472

Products & Services: Mutagenesis Services

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

Authors: Luka Bacic, Guillaume Gaullier, Anton Sabantsev, Laura C Lehmann, Klaus Brackmann, Despoina Dimakou, Mario Halic, Graeme Hewitt, Simon J Boulton, Sebastian Deindl

Journal: Elife

PubMed ID: 34486521

Doi: 10.7554/eLife.71420

Products & Services: Custom Vector Construction

Baculovirus infection affects caterpillar chemoperception

Authors: Angel Llopis-Giménez, Gabriela Caballero-Vidal, Emmanuelle Jacquin-Joly, Cristina Maria Crava, Salvador Herrero

Journal: Insect Biochem Mol Biol

PubMed ID: 34536505

Doi: 10.1016/j.ibmb.2021.103648

Products & Services: ORF cDNA Clones/MolecularCloud

Ackr3-Venus knock-in mouse lights up brain vasculature

Authors: Aliza T Ehrlich, Meriem Semache, Pierre Couvineau, Stefan Wojcik, Hiroyuki Kobayashi, Marcus Thelen, Florence Gross, Mireille Hogue, Christian Le Gouill, Emmanuel Darcq, Michel Bouvier, Brigitte L Kieffer

Journal: Mol Brain

PubMed ID: 34583741

Doi: 10.1186/s13041-021-00862-y

Products & Services: Catalog Peptides

Antibody Screening Results for Anti-Nucleocapsid Antibodies Toward the Development of a Lateral Flow Assay to Detect SARS-CoV-2 Nucleocapsid Protein

Authors: David M Cate, Joshua D Bishop, Helen V Hsieh, Veronika A Glukhova, Luis F Alonzo, H Gleda Hermansky, Brianda Barrios-Lopez, Benjamin D Grant, Caitlin E Anderson, Ethan Spencer, Samantha Kuhn, Ryan Gallagher, Rafael Rivera, Crissa Bennett, Samantha A Byrnes, John T Connelly, Puneet K Dewan, David S Boyle, Bernhard H Weigl, Kevin P Nichols

Journal: ACS Omega

PubMed ID: 34608447

Doi: 10.1021/acsomega.1c01253

Products & Services: Gene Synthesis

Intranasal vaccination with a recombinant protein CTA1-DD-RBF protects mice against hRSV infection

Authors: Hai Li, Hu Ren, Yan Zhang, Lei Cao, Wenbo Xu

Journal: Sci Rep

PubMed ID: 34545126

Doi: 10.1038/s41598-021-97535-6

Products & Services: Endotoxin Detection & Removal System

High-Level Expression of Palmitoylated MPP1 Recombinant Protein in Mammalian Cells

Authors: Agnieszka Chytła, Weronika Gajdzik-Nowak, Agnieszka Biernatowska, Aleksander F Sikorski, Aleksander Czogalla

Journal: Membranes (Basel)

PubMed ID: 34564532

Doi: 10.3390/membranes11090715

Products & Services: Custom Vector Construction

Gimap5 Inhibits Lung Cancer Growth by Interacting With M6PR

Authors: Pei Dai, Zhongxiang Tang, Pinglang Ruan, Ousman Bajinka, Dan Liu, Yurong Tan

Journal: Front Oncol

PubMed ID: 34604035

Doi: 10.3389/fonc.2021.699847

Products & Services: Custom Vector Construction

DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation

Authors: Hung-Hsi Chen, Hsin-I Yu, Rudy Rudy, Sim-Lin Lim, Yi-Fen Chen, Shu-Hsing Wu, Shu-Chun Lin, Muh-Hwa Yang, Woan-Yuh Tarn

Journal: iScience

PubMed ID: 34568799

Doi: 10.1016/j.isci.2021.103086

Products & Services: Catalog Antibody

The impact of chromophore choice on the assembly kinetics and primary photochemistry of a red/green cyanobacteriochrome

Authors:

Journal: Phys Chem Chem Phys

PubMed ID: 34374395

Doi: 10.1039/d1cp02696h

Products & Services: Bacterial Expression

High incidences of chromosomal aberrations and Y chromosome micro-deletions as prominent causes for recurrent pregnancy losses in highly ethnic and consanguineous population

Authors: Arshad A Pandith, Usma Manzoor, Ina Amin, Abida Ahmad, Masarat Rashid, Mahrukh H Zargar, Shayesta Rah, Fayaz A Dar, Iqbal Qasim, Dheera Sanadhya

Journal: Arch Gynecol Obstet

PubMed ID: 34542677

Doi: 10.1007/s00404-021-06235-z

Products & Services: Gene Synthesis

Expression of IL-20 Receptor Subunit β Is Linked to EAE Neuropathology and CNS Neuroinflammation

Authors: Jacquelyn R Dayton, Yinyu Yuan, Lisa P Pacumio, Bryce G Dorflinger, Samantha C Yoo, Mariah J Olson, Sara I Hernández-Suárez, Moira M McMahon, Lillian Cruz-Orengo

Journal: Front Cell Neurosci

PubMed ID: 34557075

Doi: 10.3389/fncel.2021.683687

Products & Services: Recombinant Proteins

Genome-scale identification of () family genes and molecular characterization of their responses to diverse nutrient stresses in allotetraploid rapeseed

Authors: Ying Liu, Ying-Peng Hua, Huan Chen, Ting Zhou, Cai-Peng Yue, Jin-Yong Huang

Journal: PeerJ

PubMed ID: 34603847

Doi: 10.7717/peerj.12007

Products & Services: Protein Tools

Physiologically Relevant Free Ca Ion Concentrations Regulate STRA6-Calmodulin Complex Formation via the BP2 Region of STRA6

Authors: Brianna D Young, Kristen M Varney, Paul T Wilder, Brianna K Costabile, Edwin Pozharski, Mary E Cook, Raquel Godoy-Ruiz, Oliver B Clarke, Filippo Mancia, David J Weber

Journal: J Mol Biol

PubMed ID: 34592217

Doi: 10.1016/j.jmb.2021.167272

Products & Services: Proteins, Expression, Isolation and Analysis

Chronic colitis upregulates microRNAs suppressing brain-derived neurotrophic factor in the adult heart

Authors: Yanbo Tang, Kevin T Kline, Xiaoying S Zhong, Ying Xiao, Haifeng Lian, Jun Peng, Xiaowei Liu, Don W Powell, Guodu Tang, Qingjie Li

Journal: PLoS ONE

PubMed ID: 34543287

Doi: 10.1371/journal.pone.0257280

Products & Services: Recombinant Proteins

Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription

Authors: John Pang, Nam Nguyen, Jens Luebeck, Laurel Ball, Andrey Finegersh, Shuling Ren, Takuya Nakagawa, Mitchell Flagg, Sayed Sadat, Paul S Mischel, Guorong Xu, Kathleen Fisch, Theresa Guo, Gabrielle Cahill, Bharat Panuganti, Vineet Bafna, Joseph Califano

Journal: Clin Cancer Res

PubMed ID: 34548317

Doi: 10.1158/1078-0432.CCR-21-2484

Products & Services: Custom Vector Construction

Androgen Receptor-Mediated Nuclear Transport of NRDP1 in Prostate Cancer Cells Is Associated with Worse Patient Outcomes

Authors: Thomas Steele, Anhao Sam, Shawna Evans, Elizabeth Browning, Sheryl Krig, Katelyn Macias, Adarsh Konda, Salma Siddiqui, Blythe Durbin-Johnson, Paramita Ghosh, Ruth Vinall

Journal: Cancers (Basel)

PubMed ID: 34503235

Doi: 10.3390/cancers13174425

Products & Services: Proteins, Expression, Isolation and Analysis

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Authors: Qiufeng Liu, Dehua Yang, Youwen Zhuang, Tristan I Croll, Xiaoqing Cai, Antao Dai, Xinheng He, Jia Duan, Wanchao Yin , Chenyu Ye, Fulai Zhou, Beili Wu, Qiang Zhao, H Eric Xu, Ming-Wei Wang, Yi Jiang

Journal: Nat Chem Biol.

PubMed ID: 34556862

Doi: 10.1038/s41589-021-00841-3

Products & Services: Peptide Synthesis

Human cytomegalovirus expands a CD8+ T cell population with loss of BCL11B expression and gain of NK cell identity

Authors: Rosa Sottile, M Kazim Panjwani, Colleen M Lau, Anthony F Daniyan, Kento Tanaka, Juliet N Barker, Renier J Brentjens, Joseph C Sun, Jean-Benoît Le Luduec, Katharine C Hsu

Journal: Sci Immunol

PubMed ID: 34559552

Doi: 10.1126/sciimmunol.abe6968

Products & Services: Gene Synthesis

Combining spike- and nucleocapsid-based vaccines improves distal control of SARS-CoV-2

Authors: Tanushree Dangi, Jacob Class, Nicole Palacio, Justin M Richner, Pablo Penaloza MacMaster

Journal: Cell Rep

PubMed ID: 34450033

Doi: 10.1016/j.celrep.2021.109664

Products & Services: Peptide Array Services

Design and Selection of Engineered Lytic Proteins With Decolonizing Activity

Authors: Diana Gutiérrez, Lorena Rodríguez-Rubio, Patricia Ruas-Madiedo, Lucía Fernández, Ana Belén Campelo, Yves Briers, Martin Weiss Nielsen, Karl Pedersen, Rob Lavigne, Pilar García, Ana Rodríguez

Journal: Front Microbiol

PubMed ID: 34594314

Doi: 10.3389/fmicb.2021.723834

Products & Services: Custom Vector Construction

A phage-encoded nucleoid associated protein compacts both host and phage DNA and derepresses H-NS silencing

Authors: Bokyung Son, Jennifer Patterson-West, Melissa Arroyo-Mendoza, Revathy Ramachandran, James R Iben, Jingen Zhu, Venigalla Rao, Emilios K Dimitriadis, Deborah M Hinton

Journal: Nucleic Acids Res

PubMed ID: 34365505

Doi: 10.1093/nar/gkab678

Products & Services: Gene Synthesis

The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid-liquid phase separation

Authors: Izzy Owen, Debra Yee, Hala Wyne, Theodora Myrto Perdikari, Victoria Johnson, Jeremy Smyth, Robert Kortum, Nicolas L Fawzi, Frank Shewmaker

Journal: J Cell Sci

PubMed ID: 34357401

Doi: 10.1242/jcs.258578

Products & Services: Proteins, Expression, Isolation and Analysis

miR‑32‑5p suppresses the proliferation and migration of pancreatic adenocarcinoma cells by targeting TLDC1

Authors: Peng Yuan, Chaofeng Tang, Bendong Chen, Peng Lei, Jianjun Song, Guojun Xin, Zuozheng Wang, Yongfeng Hui, Weijie Yao, Genwang Wang, Guozhong Zhao

Journal: Mol Med Rep

PubMed ID: 34468015

Doi: 10.3892/mmr.2021.12392

Products & Services: Custom Vector Construction

Long noncoding RNA LAMTOR5-AS1 interference affects microRNA-506-3p/E2F6-mediated behavior of non-small cell lung cancer cells

Authors: Guojie Chen, Kai Wang, Guoshu Li, Leidong Wang, Yangyang Xiao, Bo Chen

Journal: Oncol Res

PubMed ID: 34588094

Doi: 10.3727/096504021X16328213967104

Products & Services: Gene Synthesis

Myeloma patients with COVID-19 have superior antibody responses compared to patients fully vaccinated with the BNT162b2 vaccine

Authors: Maria Gavriatopoulou, Evangelos Terpos, Panagiotis Malandrakis, Ioannis Ntanasis-Stathopoulos, Alexandros Briasoulis, Sentiljana Gumeni, Despina Fotiou, Eleni-Dimitra Papanagnou, Magdalini Migkou, Foteini Theodorakakou, Evangelos Eleutherakis-Papaiakovou, Nikolaos Kanellias, Ioannis P Trougakos, Efstathios Kastritis, Meletios-Athanasios Dimopoulos

Journal: Br J Haematol

PubMed ID: 34528249

Doi: 10.1111/bjh.17841

Products & Services: PCR and Cloning

A human antibody against human endothelin receptor type A that exhibits antitumor potency

Authors: Man-Seok Ju, Hye-Mi Ahn, Seong-Gu Han, Sanghwan Ko, Jung-Hyun Na, Migyeong Jo, Chung Su Lim, Byoung Joon Ko, Yeon Gyu Yu, Won-Kyu Lee, Youn-Jae Kim, Sang Taek Jung

Journal: Exp Mol Med

PubMed ID: 34588605

Doi: 10.1038/s12276-021-00678-9

Products & Services: Proteins, Expression, Isolation and Analysis

Genome editing with type II-C CRISPR-Cas9 systems from Neisseria meningitidis in rice

Authors: Rongfang Xu, Ruiying Qin, Hongjun Xie, Juan Li, Xiaoshuang Liu, Mingdong Zhu, Yang Sun, Yinghong Yu, Pingli Lu, Pengcheng Wei

Journal: Plant Biotechnol J

PubMed ID: 34582079

Doi: 10.1111/pbi.13716

Products & Services: Synthetic sgRNA and crRNA Service

Neutralizing Antibodies against SARS-CoV-2, Anti-Ad5 Antibodies, and Reactogenicity in Response to Ad5-nCoV (CanSino Biologics) Vaccine in Individuals with and without Prior SARS-CoV-2

Authors: Jorge Hernández-Bello, José Javier Morales-Núñez, Andrea Carolina Machado-Sulbarán, Saúl Alberto Díaz-Pérez, Paola Carolina Torres-Hernández, Paulina Balcázar-Félix, Jesús Alberto Gutiérrez-Brito, José Alvaro Lomelí-Nieto, José Francisco Muñoz-Valle

Journal: Vaccines (Basel)

PubMed ID: 34579284

Doi: 10.3390/vaccines9091047

Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity

Authors: Shang Yu Gong, Debashree Chatterjee, Jonathan Richard, Jérémie Prévost, Alexandra Tauzin, Romain Gasser, Yuxia Bo, Dani Vézina, Guillaume Goyette, Gabrielle Gendron-Lepage, Halima Medjahed, Michel Roger, Marceline Côté, Andrés Finzi

Journal: Virology

PubMed ID: 34536797

Doi: 10.1016/j.virol.2021.09.001

Products & Services: Recombinant Proteins

Modulation of heterologous protein secretion in the thermotolerant methylotrophic yeast Ogataea thermomethanolica TBRC 656 by CRISPR-Cas9 system

Authors: Worarat Kruasuwan, Aekkachai Puseenam, Chitwadee Phithakrotchanakoon, Sutipa Tanapongpipat, Niran Roongsawang

Journal: PLoS ONE

PubMed ID: 34582499

Doi: 10.1371/journal.pone.0258005

Products & Services: Gene Synthesis

An analysis of antibody responses and clinical sequalae of the Sinopharm HB02 COVID19 vaccine in dialysis patients in the United Arab Emirates

Authors: Stephen Geoffrey Holt, Sally Mahmoud, Wasim Ahmed, Juan Manuel Acuna, Ayman Kamal Al Madani, Islam Eltantawy, Walid Abbas Zaher, Gareth John Goodier, Nawal Ahmed Al Kaabi, Ali Abdulkareem Al Obaidli

Journal: Nephrology (Carlton)

PubMed ID: 34569677

Doi: 10.1111/nep.13980

ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier

Authors: Xihua Yue , Yi Qian , Lianhui Zhu , Bopil Gim, Mengjing Bao , Jie Jia , Shuaiyang Jing , Yijing Wang , Chuanting Tan , Francesca Bottanelli , Pascal Ziltener , Sunkyu Choi , Piliang Hao , Intaek Lee

Journal: BMC Biol

PubMed ID: 34493279

Doi: 10.1186/s12915-021-01137-7

Products & Services: Proteins, Expression, Isolation and Analysis

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation

Authors: Hongyi Zhou, Huabo Su, Weiqin Chen

Journal: Int J Mol Sci

PubMed ID: 34502418

Doi: 10.3390/ijms22179509

Products & Services: CRISPR Plasmids

A Cross-Reactive Monoclonal Antibody Against Neuraminidases of Both H9N2 and H3N2 Influenza Viruses Shows Protection in Mice Challenging Models

Authors: Fei Wang, Zhimin Wan, Jinsen Wu, Yajuan Wang, Hui Fu, Hongxia Shao, Kun Qian, Wei Gao, Jianqiang, Aijian Qin

Journal: Frontiers in Microbiology

Doi: 10.3389/fmicb.2021.730449

Products & Services: Gene Synthesis

Application of the amplification-free SERS-based CRISPR/Cas12a platform in the identification of SARS-CoV-2 from clinical samples

Authors: Jiajie Liang, Peijun Teng, Wei Xiao, Guanbo He, Qifang Song, Ying Zhang, Bin Peng, Gan Li, Liangshan Hu, Donglin Cao, Yong Tang

Journal: J Nanobiotechnology

PubMed ID: 34496881

Doi: 10.1186/s12951-021-01021-0

Products & Services: DNA Sequencing

A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease

Authors: Stephanie Patchett, Zongyang Lv, Wioletta Rut, Miklos Békés, Marcin Drag, Shaun K Olsen, Tony T Huang

Journal: Cell Rep

PubMed ID: 34547223

Doi: 10.1016/j.celrep.2021.109754

Products & Services: DNA Sequencing

Fusion of cellobiose phosphorylase and potato alpha-glucan phosphorylase facilitates substrate channeling for enzymatic conversion of cellobiose to starch

Authors: Xinyu Liu, Huawei Hou, Yapeng Li, Sen Yang, Hui Lin, Hongge Chen

Journal: Prep Biochem Biotechnol

PubMed ID: 34550864

Doi: 10.1080/10826068.2021.1977949

Products & Services: DNA Sequencing

Structure and function relationship of OqxB efflux pump from Klebsiella pneumoniae

Authors: Nagakumar Bharatham, Purnendu Bhowmik, Maho Aoki, Ui Okada, Sreevalli Sharma, Eiki Yamashita, Anirudh P Shanbhag, Sreenath Rajagopal, Teby Thomas, Maitrayee Sarma, Riya Narjari, Savitha Nagaraj, Vasanthi Ramachandran, Nainesh Katagihallimath, Santanu Datta, Satoshi Murakami

Journal: Nat Commun

PubMed ID: 34518546

Doi: 10.1038/s41467-021-25679-0

Products & Services: DNA Sequencing

Association of a GATA Binding Protein 4 Polymorphism with the Risk of Hypospadias in the Chinese Children

Authors: Jiawei Chen, Xinhai Cui, Aiwu Li, Guowei Li, Fengyin Sun

Journal: Urol Int

PubMed ID: 34569527

Doi: 10.1159/000518644

Products & Services: Custom Vector Construction

NMPylation and de-NMPylation of SARS-CoV-2 nsp9 by the NiRAN domain

Authors: Bing Wang, Dmitri Svetlov, Irina Artsimovitch

Journal: Nucleic Acids Res

PubMed ID: 34352100

Doi: 10.1093/nar/gkab677

Products & Services: Custom Vector Construction

A genome-wide screen reveals the involvement of enterobactin-mediated iron acquisition in Escherichia coli survival during copper stress

Authors: Kaitlin Casanova-Hampton, Alexis Carey, Sarah Kassam, Alyssa Garner, George L Donati, Shankar Thangamani, Sargurunathan Subashchandrabose

Journal: Metallomics

PubMed ID: 34415046

Doi: 10.1093/mtomcs/mfab052

Products & Services: Custom Vector Construction

De novo design of tyrosine and serine kinase-driven protein switches

Authors: Nicholas B Woodall, Zara Weinberg, Jesslyn Park, Florian Busch, Richard S Johnson, Mikayla J Feldbauer, Michael Murphy, Maggie Ahlrichs, Issa Yousif, Michael J MacCoss, Vicki H Wysocki, Hana El-Samad, David Baker

Journal: Nat Struct Mol Biol

PubMed ID: 34518698

Doi: 10.1038/s41594-021-00649-8

Products & Services: Custom Vector Construction

The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity

Authors: Konrad J Mostert, Nandini Sharma, Marianne van der Zwaag, Roxine Staats, Lizbé Koekemoer, Ruchi Anand, Ody C M Sibon, Erick Strauss

Journal: ACS Chem Biol

PubMed ID: 34582681

Doi: 10.1021/acschembio.1c00535

Products & Services: Custom Vector Construction

Feline thymidine kinase 1: molecular characterization and evaluation of its serum form as a diagnostic biomarker

Authors: Liya Wang, Hanan Sharif, Sara Saellström, Henrik Rönnberg, Staffan Eriksson

Journal: BMC Vet Res

PubMed ID: 34579716

Doi: 10.1186/s12917-021-03030-5

Products & Services: Custom Vector Construction

Molecular basis of human ATM kinase inhibition

Authors: K Stakyte, M Rotheneder, K Lammens, J D Bartho, U Grädler, T Fuchß, U Pehl, A Alt, E van de Logt, K P Hopfner

Journal: Nat Struct Mol Biol

PubMed ID: 34556870

Doi: 10.1038/s41594-021-00654-x

Products & Services: Custom Vector Construction

Zinc-finger protein MdBBX7/MdCOL9, a target of MdMIEL1 E3 ligase, confers drought tolerance in apple

Authors: Pengxiang Chen, Fang Zhi, Xuewei Li, Wenyun Shen, Mingjia Yan, Jieqiang He, Chana Bao, Tianle Fan, Shuangxi Zhou, Fengwang Ma, Qingmei Guan

Journal: Plant Physiol

PubMed ID: 34618120

Doi: 10.1093/plphys/kiab420

Products & Services: Custom RNAi Services

Spectroscopic evidence of tetanus toxin translocation domain bilayer-induced refolding and insertion

Authors: Pierce T O'Neil, Victor Vasquez-Montes, Liskin Swint-Kruse, Michael R Baldwin, Alexey S Ladokhin

Journal: Biophys J

PubMed ID: 34555358

Doi: 10.1016/j.bpj.2021.09.030

Products & Services: Codon Optimization

Spike protein of SARS-CoV-2 activates macrophages and contributes to induction of acute lung inflammation in male mice

Authors: Xiaoling Cao, Yan Tian, Vi Nguyen, Yuping Zhang, Chao Gao, Rong Yin, Wayne Carver, Daping Fan, Helmut Albrecht, Taixing Cui, Wenbin Tan

Journal: FASEB J

PubMed ID: 34365657

Doi: 10.1096/fj.202002742RR

Products & Services: Codon Optimization

Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing

Authors: Sarah A Schoonraad, Kristine M Fischenich, Kevin N Eckstein, Victor Crespo-Cuevas, Lea M Savard, Archish Muralidharan, Andrew A Tomaschke, Asais Camila Uzcategui, Mark A Randolph, Robert R McLeod, Virginia L Ferguson, Stephanie J Bryant

Journal: Biofabrication

PubMed ID: 34479218

Doi: 10.1088/1758-5090/ac23ab

Products & Services: Catalog Peptides

Serological Assays for Assessing Postvaccination SARS-CoV-2 Antibody Response

Authors: Sally A Mahmoud, Subhashini Ganesan, Shivaraj Naik, Safaa Bissar, Isra Al Zamel, K N Warren, Walid A Zaher, Gulfaraz Khan

Journal: Microbiol Spectr

PubMed ID: 34585943

Doi: 10.1128/Spectrum.00733-21

Products & Services: Serology SARS-Cov-2 detection kits

Isotype-Specific Fc Effector Functions Enhance Antibody-Mediated Rift Valley Fever Virus Protection

Authors: Haley N Cartwright, Dominique J Barbeau, Anita K McElroy

Journal: mSphere

PubMed ID: 34494884

Doi: 10.1128/mSphere.00556-21

Products & Services: Catalog Antibody

Lysine Residues in the MK-Rich Region Are Not Required for Binding of the PbsP Protein From Group B Streptococci to Plasminogen

Authors: Francesco Coppolino, Letizia Romeo, Giampiero Pietrocola, Germana Lentini, Giuseppe Valerio De Gaetano, Giuseppe Teti, Roberta Galbo, Concetta Beninati

Journal: Front Cell Infect Microbiol

PubMed ID: 34568085

Doi: 10.3389/fcimb.2021.679792

Products & Services: Peptide Synthesis

Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs

Authors: Lifeng Fu, Shuai Shao, Yong Feng, Fei Ye, Xue Sun, Qingling Wang, Feng Yu, Qisheng Wang, Baoying Huang, Peihua Niu, Xuebing Li, Catherine C L Wong, Jianxun Qi, Wenjie Tan, George Fu Gao

Journal: MBio

PubMed ID: 34579576

Doi: 10.1128/mBio.02220-21

Products & Services: Peptide Synthesis

Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA binding induce Aicardi-Goutières-syndrome-like encephalopathy

Authors: Taisuke Nakahama, Yuki Kato, Toshiharu Shibuya, Maal Inoue, Jung In Kim, Tuangtong Vongpipatana, Hiroyuki Todo, Yanfang Xing, Yukio Kawahara

Journal: Immunity

PubMed ID: 34525338

Doi: 10.1016/j.immuni.2021.08.022

Products & Services: Stable Cell Lines

Development of a Recombinant RBD Subunit Vaccine for SARS-CoV-2

Authors: Yi-Sheng Sun, Jing-Jing Zhou, Han-Ping Zhu, Fang Xu, Wen-Bin Zhao, Hang-Jing Lu, Zhen Wang, Shu-Qing Chen, Ping-Ping Yao, Jian-Min Jiang, Zhan Zhou

Journal: Viruses

PubMed ID: 34696367

Doi: 10.3390/v13101936

Products & Services: SARS-CoV-2 qRT-PCR Detection Assay

Vaspin Mediates the Intraorgan Crosstalk Between Heart and Adipose Tissue in Lipoatrophic Mice

Authors: Donghui Zhang, Hong Zhu, Enbo Zhan, Fan Wang, Yue Liu, Wei Xu, Xian Liu, Jingjin Liu, Shufeng Li, Yong Pan, Yongshun Wang, Wei Cao

Journal: Front Cell Dev Biol

PubMed ID: 34631690

Doi: 10.3389/fcell.2021.647131

Products & Services: Recombinant Antibody Expression

Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain

Authors: Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Svetlana A Semenova, Avinash Chekuru, Paul Wirsching, Volker Kroehne, Saygın Bilican, Shady Sayed, Sylke Winkler, Sandra Spieß, Anja Machate, Jan Kaslin, Pertti Panula, Michael Brand

Journal: PLoS Genet

PubMed ID: 34516550

Doi: 10.1371/journal.pgen.1009794

Products & Services: Proteins, Expression, Isolation and Analysis

The evidence for and consequences of metabotropic glutamate receptor heterodimerization

Authors: Tyler W McCullock, Paul J Kammermeier

Journal: Neuropharmacology

PubMed ID: 34547332

Doi: 10.1016/j.neuropharm.2021.108801

Products & Services: Proteins, Expression, Isolation and Analysis

Tagging and Capturing of Lentiviral Vectors Using Short RNAs

Authors: Martin Panigaj, Michael P Marino, Jakob Reiser

Journal: Int J Mol Sci

PubMed ID: 34638603

Doi: 10.3390/ijms221910263

Products & Services: Plasmid DNA Preparation

RBD-homodimer, a COVID-19 subunit vaccine candidate, elicits immunogenicity and protection in rodents and nonhuman primates

Authors: Xiaoyan Pan, Jian Shi, Xue Hu, Yan Wu, Liang Zeng, Yanfeng Yao, Weijuan Shang, Kunpeng Liu, Ge Gao, Weiwei Guo, Yun Peng, Shaohong Chen, Xiaoxiao Gao, Cheng Peng, Juhong Rao, Jiaxuan Zhao, Cheng Gong, Hui Zhou, Yudong Lu, Zili Wang, Xiliang Hu, WenJuan Cong, Lijuan Fang, Yongxiang Yan, Jing Zhang, Hui Xiong, Jizu Yi, Zhiming Yuan, Pengfei Zhou, Chao Shan, Gengfu Xiao

Journal: Cell Discov

PubMed ID: 34493710

Doi: 10.1038/s41421-021-00320-y

Products & Services: Plasmid DNA Preparation

Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo

Authors: Debashis Dutta, Malabendu Jana, Moumita Majumder, Susanta Mondal, Avik Roy, Kalipada Pahan

Journal: Nat Commun

PubMed ID: 34508096

Doi: 10.1038/s41467-021-25767-1

Products & Services: Peptide Synthesis

Mass balance method for SI-traceable purity assignment of synthetic oxytocin

Authors: Sheng Wang, Peize Wu, Ming Li, Ting Huang, Naijie Shi, Liuxing Feng, Hongmei Li

Journal: J Pharm Biomed Anal

PubMed ID: 34656934

Doi: 10.1016/j.jpba.2021.114401

Products & Services: Peptide Synthesis

Surface-enhanced Raman scattering-based detection of plasmin activity by specific peptide substrate

Authors: Nazife Nur Yazgan, Tugba Bulat, Ali Topcu, Fahriye Ceyda Dudak, Ismail Hakki Boyaci, Uğur Tamer

Journal: Food Chem

PubMed ID: 34624781

Doi: 10.1016/j.foodchem.2021.131235

Products & Services: Peptide Synthesis

Identification and Characterization of Rift Valley Fever Virus-Specific T Cells Reveals a Dependence on CD40/CD40L Interactions for Prevention of Encephalitis

Authors: Dominique J Barbeau, Haley N Cartwright, Jessica R Harmon, Jessica R Spengler, Christina F Spiropoulou, John Sidney, Alessandro Sette, Anita K McElroy

Journal: J Virol

PubMed ID: 34495703

Doi: 10.1128/JVI.01506-21

Products & Services: Peptide Synthesis

Optimised Heterologous Expression and Functional Analysis of the F1-Capsular Antigen Regulator Caf1R

Authors: Dharmender K Gahlot, Gyles Ifill, Sheila MacIntyre

Journal: Int J Mol Sci

PubMed ID: 34575967

Doi: 10.3390/ijms22189805

Products & Services: ORF cDNA Clones/MolecularCloud

Glucagon-Like Peptide-2 Modulates Enteric Paneth Cells Immune Response and Alleviates Gut Inflammation During Intravenous Fluid Infusion in Mice With a Central Catheter

Authors: Guifang Deng, Qiucheng Lei, Xuejin Gao, Yupeng Zhang, Huazhen Zheng, Jingcheng Bi, Xinying Wang

Journal: Front Nutr

PubMed ID: 34540875

Doi: 10.3389/fnut.2021.688715

Products & Services: Nucleic Acid Purification & Analysis

Exploration of the Role of the C-Terminal Domain of Human DNA Topoisomerase IIα in Catalytic Activity

Authors: Ashley C Dougherty, Mariam G Hawaz, Kristine G Hoang, Judy Trac, Jacob M Keck, Carmen Ayes, Joseph E Deweese

Journal: ACS Omega

PubMed ID: 34660952

Doi: 10.1021/acsomega.1c02083

Products & Services: Mutagenesis Services

The DNA Recognition Motif of GapR Has an Intrinsic DNA Binding Preference towards AT-rich DNA

Authors: Qian Huang, Bo Duan, Zhi Qu, Shilong Fan, Bin Xia

Journal: Molecules

PubMed ID: 34641320

Doi: 10.3390/molecules26195776

Products & Services: Mutagenesis Services

Author Correction: Enhanced genome editing efficiency of CRISPR PLUS: Cas9 chimeric fusion proteins

Authors: Jongjin Park, Jiyoung Yoon, Daekee Kwon, Mi-Jung Han, Sunmee Choi, Slki Park, Junghyuk Lee, Kiwook Lee, Jaehwan Lee, Seunghee Lee, Kyung-Sun Kang, Sunghwa Choe

Journal: Sci Rep

PubMed ID: 34508163

Doi: 10.1038/s41598-021-98186-3

Products & Services: Mammalian Expression

Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools

Authors: Viktor Mojr, Mohammad Roghanian, Hedvig Tamman, Duy Dinh Do Pham, Magdalena Petrová, Radek Pohl, Hiraku Takada, Katleen Van Nerom, Hanna Ainelo, Julien Caballero-Montes, Steffi Jimmy, Abel Garcia-Pino, Vasili Hauryliuk, Dominik Rejman

Journal: ACS Chem Biol

PubMed ID: 34477366

Doi: 10.1021/acschembio.1c00398

Products & Services: Mammalian Expression

Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation

Authors: Eleonora Turco, Adriana Savova, Flora Gere, Luca Ferrari, Julia Romanov, Martina Schuschnig, Sascha Martens

Journal: Nat Commun

PubMed ID: 34471133

Doi: 10.1038/s41467-021-25572-w

Products & Services: Insect Expression

Multiple strategies for metabolic engineering of Escherichia coli for efficient production of glycolate

Authors: Tong Zhu, Die Yao, Di Li, Hongtao Xu, Shiru Jia, Changhao Bi, Jun Cai, Xinna Zhu, Xueli Zhang

Journal: Biotechnol Bioeng

PubMed ID: 34491579

Doi: 10.1002/bit.27934

Products & Services: GenParts™ DNA Fragments

Spectroscopic and functional characterization of the [2Fe-2S] scaffold protein Nfu from Synechocystis PCC6803

Authors: Zechariah Thompson, Insiya Fidai, Christine Wachnowsky, Amber L Hendricks, J A Cowan

Journal: Biochimie

PubMed ID: 34582998

Doi: 10.1016/j.biochi.2021.09.013

Products & Services: Gene Synthesis

CriTER-A: A Novel Temperature-Dependent Noncoding RNA Switch in the Telomeric Transcriptome of

Authors: Cristina Romero-López, Alfredo Berzal-Herranz, José Luis Martínez-Guitarte, Mercedes de la Fuente

Journal: Int J Mol Sci

PubMed ID: 34638651

Doi: 10.3390/ijms221910310

Products & Services: Plasmid DNA Preparation

CAMKK2 regulates mitochondrial function by controlling succinate dehydrogenase expression, post-translational modification, megacomplex assembly, and activity in a cell-type-specific manner

Authors: Mohammad Golam Sabbir, Carla G Taylor, Peter Zahradka

Journal: Cell Commun Signal

PubMed ID: 34563205

Doi: 10.1186/s12964-021-00778-z

Products & Services: ORF cDNA Clones/MolecularCloud

Sex-specific pubertal and metabolic regulation of Kiss1 neurons via Nhlh2

Authors: Silvia Leon, Rajae Talbi, Elizabeth A McCarthy, Kaitlin Ferrari, Chrysanthi Fergani, Lydie Naule, Ji Hae Choi, Rona S Carroll, Ursula B Kaiser, Carlos F Aylwin, Alejandro Lomniczi, Víctor M Navarro

Journal: Elife

PubMed ID: 34494548

Doi: 10.7554/eLife.69765

Products & Services: Custom Vector Construction

Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells

Authors: Cesar L Cuevas-Velazquez, Tamara Vellosillo, Karina Guadalupe, Hermann Broder Schmidt, Feng Yu, David Moses, Jennifer A N Brophy, Dante Cosio-Acosta, Alakananda Das, Lingxin Wang, Alexander M Jones, Alejandra A Covarrubias, Shahar Sukenik, José R Dinneny

Journal: Nat Commun

PubMed ID: 34521831

Doi: 10.1038/s41467-021-25736-8

Products & Services: GenParts™ DNA Fragments

A Secreted Chorismate Mutase from pv Attenuates Virulence and Walnut Blight Symptoms

Authors: Renata de A B Assis, Cíntia H D Sagawa, Paulo A Zaini, Houston J Saxe, Phillip A Wilmarth, Brett S Phinney, Michelle Salemi, Leandro M Moreira, Abhaya M Dandekar

Journal: Int J Mol Sci

PubMed ID: 34638715

Doi: 10.3390/ijms221910374

Products & Services: Mutagenesis Services

Elucidating mechanisms of antitumor immunity mediated by live oncolytic vaccinia and heat-inactivated vaccinia

Authors: Weiyi Wang, Shuaitong Liu, Peihong Dai, Ning Yang, Yi Wang, Rachel A Giese, Taha Merghoub, Jedd Wolchok, Liang Deng

Journal: J Immunother Cancer

PubMed ID: 34593618

Doi: 10.1136/jitc-2021-002569

Products & Services: Recombinant Antibody Expression

Altered metabolomic states elicited by Flg22 and FlgII-28 in Solanum lycopersicum: intracellular perturbations and metabolite defenses

Authors: Dylan R Zeiss, Paul A Steenkamp, Lizelle A Piater, Ian A Dubery

Journal: BMC Plant Biol

PubMed ID: 34548030

Doi: 10.1186/s12870-021-03200-5

Products & Services: Catalog Peptides

A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis

Authors: Jie Zheng, Lu Yao, Yijing Zhou, Xiaoqun Gu, Can Wang, Kaifan Bao, Yang Sun, Min Hong

Journal: Cell Death Dis

PubMed ID: 34561424

Doi: 10.1038/s41419-021-04159-9

Products & Services: Custom DNA/RNA Oligos

Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

Authors: Jaime L Chao, Michael Korzinkin, Alex Zhavoronkov, Ivan V Ozerov, Matthew T Walker, Kathleen Higgins, Mark W Lingen, Evgeny Izumchenko, Peter A Savage

Journal: Cell Rep Med

PubMed ID: 34622236

Doi: 10.1016/j.xcrm.2021.100399

Products & Services: Catalog Peptides