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The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis

Authors: Jihui Zhang, Hongwei Lei, Xiu Li

Journal: Bioengineered

PubMed ID: 34965184

Doi: 10.1080/21655979.2021.2001911

Products & Services: Gene Synthesis

Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma

Authors: Huaijun Wang, Zhongqian Hu, Uday Kumar Sukumar, Rajendran Jc Bose, Arsenii Telichko, Jeremy J Dahl, Ramasamy Paulmurugan

Journal: Nanotheranostics

PubMed ID: 34976581

Doi: 10.7150/ntno.63320

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Sterility of Sustained-release Buprenorphine

Authors: Shraddha I Cantara, Crystal Gergye, Vanessa K Lee, Michael Huerkamp

Journal: J Am Assoc Lab Anim Sci

PubMed ID: 35082006

Doi: 10.30802/AALAS-JAALAS-21-000105

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ADAM17 regulates the proliferation and extracellular matrix of keloid fibroblasts by mediating the EGFR/ERK signaling pathway

Authors: Xin Le, You-Fen Fan

Journal: J Plast Surg Hand Surg

PubMed ID: 34978504

Doi: 10.1080/2000656X.2021.2017944

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Blue-light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection

Authors: Shaista Naqvi, Qin He, Franziska Trusch, Huishan Qiu, Jasmine Pham, Qingguo Sun, John M Christie, Eleanor M Gilroy, Paul R J Birch

Journal: New Phytol

PubMed ID: 34923631

Doi: 10.1111/nph.17929

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Investigation of putative antimicrobial peptides in Carassius gibel, revealing a practical approach to screening antimicrobials

Authors: Yujun Zhang, Ping Deng, Caijiao Dai, Mengke Wu, Xueqin Liu, Lijuan Li, Xiaoyi Pan, Junfa Yuan

Journal: Fish Shellfish Immunol

PubMed ID: 34990806

Doi: 10.1016/j.fsi.2021.12.050

Products & Services: Recombinant Proteins

Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells

Authors: Bruna Cristina Falavinha, María Julia Barisón, Carmen Lúcia Kuniyoshi Rebelatto, Bruna Hilzendeger Marcon, Alessandra de Melo Aguiar, Evelin Brandão da Silva, Marco Augusto Stimamiglio, Patrícia Shigunov

Journal: Stem Cells Int

PubMed ID: 35047041

Doi: 10.1155/2022/4930932

Products & Services: ORF cDNA Clones/MolecularCloud

Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase

Authors: Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza, Ikechukwu Achilonu

Journal: Protein J

PubMed ID: 35083643

Doi: 10.1007/s10930-021-10037-2

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The H, N and C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1

Authors: Courtney N Johnson, Xiaoping Xu, Stephen P Holloway, David S Libich

Journal: Biomol NMR Assign

PubMed ID: 34994941

Doi: 10.1007/s12104-021-10061-4

Products & Services: Mutant Libraries

Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

Products & Services: Bacterial Expression

Hemagglutinin-based DNA vaccines containing trimeric self-assembling nanoparticles confer protection against influenza

Authors: Yongbo Qiao, Shenghui Jin, Jiaojiao Nie, Yaotian Chang, Bo Wang, Shanshan Guan, Qinghan Li, Yuhua Shi, Wei Kong, Yaming Shan

Journal: J Leukoc Biol

PubMed ID: 35040188

Doi: 10.1002/JLB.6A1021-535R

Products & Services: Mammalian Expression

K-edge anomalous SAXS for protein solution structure modeling

Authors: Karman Virk, Kento Yonezawa, Komal Choukate, Lucky Singh, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35102886

Doi: 10.1107/S205979832101247X

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High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

Products & Services: PCR Cloning and Subcloning

Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Authors: Siriorn P Watcharananan, Peera Jaru-Ampornpan, Suree Sahawongcharoen, Nattakan Naitook, Orawan Himananto, Anan Jongkaewwattana, Chavachol Setthaudom, Sasivimol Rattanasiri, Angsana Phuphuakrat, Ammarin Thakkinstian, Viroon Mavichak

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

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Inhibition of microRNA-448 suppresses CD4 T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus

Authors: Jing Zhang, Yun Guo, Yue Sun, Lihua Chang, Xiaofei Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 35121374

Doi: 10.1016/j.bbrc.2022.01.097

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Degradation of dimethachlon by a newly isolated bacterium Paenarthrobacter sp strain JH-1 relieves its toxicity against Chlorella ellipsoidea

Authors: Mingliang Zhang, Wankui Jiang, Siyuan Gao, Qian Zhu, Zhijian Ke, Mingli Jiang, Jiguo Qiu, Qing Hong

Journal: Environ Res

PubMed ID: 35031339

Doi: 10.1016/j.envres.2022.112706

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NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway

Authors: Bo Li, Qian Xiao, Liping Shan, Yongsheng Song

Journal: Cell Cycle

PubMed ID: 34974790

Doi: 10.1080/15384101.2021.2021050

Products & Services: Plasmid DNA Preparation

Hempseed () Peptides WVSPLAGRT and IGFLIIWV Exert Anti-inflammatory Activity in the LPS-Stimulated Human Hepatic Cell Line

Authors: Ivan Cruz-Chamorro, Guillermo Santos-Sánchez, Carlotta Bollati, Martina Bartolomei, Jianqiang Li, Anna Arnoldi, Carmen Lammi

Journal: J Agric Food Chem

PubMed ID: 35007086

Doi: 10.1021/acs.jafc.1c07520

Products & Services: Protein and Antibody Isolation

Clinical Potential of lncRNA PPP1R26-AS1 in Breast Cancer and Its Contribution to Cancer Progression

Authors: Shuping Zhou, Shaoli Zhang, Hui Zhang, Junxia Ma, Huangzhen Dai, Lili Qu, Meixiang Zhou

Journal: Mol Biotechnol

PubMed ID: 35064892

Doi: 10.1007/s12033-022-00452-w

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Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor

Authors: Jinliang Wang, Jie Luo, Zhiyuan Wen, Xinxin Wang, Lei Shuai, Gongxun Zhong, Chong Wang, Ziruo Sun, Weiye Chen, Jinying Ge, Renqiang Liu, Xijun Wang, Zhigao Bu

Journal: MBio

PubMed ID: 35012335

Doi: 10.1128/mbio.02443-21

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Anti-aquaporin-4 immunoglobulin G colorimetric detection by silver nanoparticles

Authors: Akemi M Higa, Ariana S Moraes, Flávio M Shimizu, Raquel G Bueno, Luís A Peroni, Francisco T Strixino, Nise A C Sousa, Elenice Deffune, Ana Lívia C Bovolato, Osvaldo N Oliveira, Doralina G Brum, Fabio L Leite

Journal: Nanomedicine

PubMed ID: 35114406

Doi: 10.1016/j.nano.2022.102531

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Genome-wide identification and expression pattern analysis of the TCP transcription factor family in

Authors: Li Yu, Qiangwen Chen, Jiarui Zheng, Feng Xu, Jiabao Ye, Weiwei Zhang, Yongling Liao, Xiaoyan Yang

Journal: Plant Signal Behav

PubMed ID: 35068346

Doi: 10.1080/15592324.2021.1994248

Products & Services: Protein Tools

Anti-Coagulant and Antimicrobial Recombinant Heparin-Binding Major Ampullate Spidroin 2 (MaSp2) Silk Protein

Authors: Pranothi Mulinti, Dorina Diekjürgen, Kristen Kurtzeborn, Narayanaganesh Balasubramanian, Shane J Stafslien, David W Grainger, Amanda E Brooks

Journal: Bioengineering (Basel)

PubMed ID: 35200400

Doi: 10.3390/bioengineering9020046

Products & Services: Gene Synthesis

Anti-Coagulant and Antimicrobial Recombinant Heparin-Binding Major Ampullate Spidroin 2 (MaSp2) Silk Protein

Authors: Pranothi Mulinti, Dorina Diekjürgen, Kristen Kurtzeborn, Narayanaganesh Balasubramanian, Shane J Stafslien, David W Grainger, Amanda E Brooks

Journal: Bioengineering (Basel)

PubMed ID: 35200400

Doi: 10.3390/bioengineering9020046

Products & Services: Gene Synthesis

lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway

Authors: Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang

Journal: Mediators Inflamm

PubMed ID: 35125964

Doi: 10.1155/2022/6979117

Products & Services: Custom DNA/RNA Oligos

Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay

Authors: Kai Zhang, Zhenqiang Fan, Yue Huang, Yuedi Ding, Minhao Xie, Minghe Wang

Journal: Talanta

PubMed ID: 34998144

Doi: 10.1016/j.talanta.2022.123207

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Antibody response following SARS-CoV-2 vaccination among patients with type 2 diabetes mellitus: A systematic review

Authors: Nanny Natalia M Soetedjo, Maria Riastuti Iryaningrum, Sherly Lawrensia, Hikmat Permana

Journal: Diabetes Metab Syndr

PubMed ID: 35104750

Doi: 10.1016/j.dsx.2022.102406

Products & Services: Protein and Antibody Reagents

Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection

Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang

Journal: Environ Sci Technol

PubMed ID: 35049283

Doi: 10.1021/acs.est.1c07172

Products & Services: Protein and Antibody Isolation

Characterization of male-biased fatty acid desaturase in the jewel wasp Nasonia vitripennis and its role in pheromone production

Authors: Jian-Qiu Cheng, Yu-Mei Tao, Jing Li, Yong-Zhuo Chen, Hao-Yuan Hu

Journal: J Exp Zool B Mol Dev Evol

PubMed ID: 34995007

Doi: 10.1002/jez.b.23120

Products & Services: Polyclonal Antibody Services

Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI9 norovirus, as revealed by structural analysis

Authors: Tomomi Kimura-Someya, Miyuki Kato-Murayama, Kazushige Katsura, Naoki Sakai, Kazutaka Murayama, Kazuharu Hanada, Mikako Shirouzu, Yuichi Someya

Journal: FEBS Open Bio

PubMed ID: 35038379

Doi: 10.1002/2211-5463.13370

Products & Services: Gene Fragments

Formation of Calprotectin-Derived Peptides in the Airways of Children with Cystic Fibrosis

Authors: Teagan S Edwards, Nina Dickerhof, Nicholas J Magon, Louise N Paton, Peter D Sly, Anthony J Kettle

Journal: J Immunol

PubMed ID: 35046105

Doi: 10.4049/jimmunol.2001017

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Development of a Salmonella-based oral vaccine to control intestinal colonization of Shiga-toxin-producing Escherichia coli (STEC) in animals

Authors: Florencia Iannino, Paula J Uriza, Cecilia M Duarte, María V Pepe, Mara S Roset, Gabriel Briones

Journal: Vaccine

PubMed ID: 35086742

Doi: 10.1016/j.vaccine.2022.01.032

Products & Services: Gene Fragments

Genome-Wide Identification and Expression Profile Analysis of the SnRK2 Gene Family in Nicotiana tabacum

Authors: Jinghao Li, Jiangyu Song, Changjun Li, Juntao Ma, Jiawang Liu, Xiaowei Zhu, Jingchao Li, Fan He, Chao Yang

Journal: Biochem Genet

PubMed ID: 35048221

Doi: 10.1007/s10528-021-10170-8

Products & Services: Protein Tools

Mesenchymal Stem Cell-Derived Exosomes Improved Cerebral Infarction via Transferring miR-23a-3p to Activate Microglia

Authors: Chenglong Dong, Maogang Chen, Binggang Cai, Cheng Zhang, Guodong Xiao, Weifeng Luo

Journal: Neuromolecular Med

PubMed ID: 35001328

Doi: 10.1007/s12017-021-08686-8

Products & Services: ORF cDNA Clones/MolecularCloud

Selection and T-cell antigenicity of synthetic long peptides derived from SARS-CoV-2

Authors: Katarzyna Piadel, Amin Haybatollahi, Angus George Dalgleish, Peter Lawrence Smith

Journal: J Gen Virol

PubMed ID: 35014605

Doi: 10.1099/jgv.0.001698

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RBP4 regulates androgen receptor expression and steroid synthesis in Sertoli cells from Bactrian camels

Authors: Qi Wang, Quanwei Zhang, Yina Li, Xingxu Zhao, Yong Zhang

Journal: Reprod Domest Anim

PubMed ID: 35014100

Doi: 10.1111/rda.14081

Products & Services: Plasmid DNA Preparation

Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells

Authors: Xiaohong Zhang, Stephen H Wright

Journal: Int J Mol Sci

PubMed ID: 35163393

Doi: 10.3390/ijms23031472

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Assessment on anti-SARS-CoV-2 receptor-binding domain antibodies among CoronaVac-vaccinated Indonesian adults

Authors: Juandy Jo, Astia Sanjaya, Reinhard Pinontoan, Maroloan Aruan, Rury Mega Wahyuni, Venansi Viktaria

Journal: Clin Exp Vaccine Res

PubMed ID: 35223672

Doi: 10.7774/cevr.2022.11.1.116

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Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses primed by an injected vaccine

Authors: Jacob Pitcovski, Nady Gruzdev, Anna Abzach, Chen Katz, Ran Ben-Adiva, Michal Brand-Shwartz, Itamar Yadid, Einav Ratzon-Ashkenazi, Ken Emquies, Hadasa Israeli, Hadar Haviv, Irena Rapoport, Itai Bloch, Roy Shadmon, Zohar Eitan, Dalia Eliahu, Talia Hilel, Morris Laster, Sigal Kremer-Tal, Tamara Byk-Tennenbaum, Ehud Shahar

Journal: Vaccine

PubMed ID: 35078662

Doi: 10.1016/j.vaccine.2022.01.025

Products & Services: Protein and Antibody Isolation

Survey of SARS-CoV-2 in dogs and cats in high-risk areas during the second wave of COVID-19 outbreak, Thailand

Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Aphinya Hangsawek, Suchart Waenkaew, Anek Mungaomklang, Ratanaporn Tangwangvivat, Alongkorn Amonsin

Journal: Zoonoses Public Health

PubMed ID: 34981900

Doi: 10.1111/zph.12907

Production and application of mouse monoclonal antibodies targeting linear epitopes in pB602L of African swine fever virus

Authors: Pengfei Wang, Chunguo Liu, Shida Wang, Lili Wen, Zhibin Shi, Yue Chi, Ming Wang, Zaisi Liu, Zhenzhao Sun, Lili Wei, Decheng Yang, Xijun He, Jingfei Wang

Journal: Arch Virol

PubMed ID: 34984562

Doi: 10.1007/s00705-021-05335-0

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Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands

Authors: Ting Zhang, Minya Zhou, Heqing Cai, Kunning Yan, Yiwen Zha, Wenwen Zhuang, Jingyan Liang, Yong Cheng

Journal: Transgenic Res

PubMed ID: 35034272

Doi: 10.1007/s11248-021-00292-5

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Protocol for structure determination of SARS-CoV-2 main protease at near-physiological-temperature by serial femtosecond crystallography

Authors: Fatma Betul Ertem, Omur Guven, Cengizhan Buyukdag, Oktay Gocenler, Esra Ayan, Busra Yuksel, Mehmet Gul, Gozde Usta, Barıs Cakılkaya, J Austin Johnson, E Han Dao, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Brandon Hayes, Mengning Liang, Mark S Hunter, Alexander Batyuk, Raymond G Sierra, Gihan Ketawala, Sabine Botha, Çağdaş Dağ, Hasan DeMirci

Journal: STAR Protoc

PubMed ID: 35194584

Doi: 10.1016/j.xpro.2022.101158

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Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue

Authors: Yingzi Tan, Miao Wang, Yijun Chen

Journal: ACS Synth Biol

PubMed ID: 35006674

Doi: 10.1021/acssynbio.1c00578

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An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein

Authors: Yahiro Mukai, Masayuki Horie, Shohei Kojima, Junna Kawasaki, Ken Maeda, Keizo Tomonaga

Journal: FEBS Lett

PubMed ID: 35043395

Doi: 10.1002/1873-3468.14290

Products & Services: Recombinant Antibody Expression

Nucleic acid biomarkers to assess graft injury after liver transplantation

Authors: Elissa Bardhi, Jennifer McDaniels, Thomas Rousselle, Daniel G Maluf, Valeria R Mas

Journal: JHEP Rep

PubMed ID: 35243279

Doi: 10.1016/j.jhepr.2022.100439

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The Role of Variants in Neurodevelopmental Diseases: Genotype-Phenotype Association

Authors: Li Shu, Neng Xiao, Jiong Qin, Qi Tian, Yanghui Zhang, Haoxian Li, Jing Liu, Qinrui Li, Weiyue Gu, Pengchao Wang, Hua Wang, Xiao Mao

Journal: Front Mol Neurosci

PubMed ID: 35095415

Doi: 10.3389/fnmol.2021.775479

Products & Services: Mammalian Expression

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma

Authors: Suraya Elfrink, Martin Ter Beest, Luuk Janssen, Marijke Baltissen, Pascal Jansen, Angelique N Kenyon, Raymond Steen, Daynelys de Windt, Philipp Michael Hagemann, Corine Hess, Dick-Johan van Spronsen, Brigiet Hoevenaars, Ellen van der Spek, Zijun Y Xu-Monette, Ken H Young, Charlotte Kaffa, Sander Bervoets, Jolien van Heek, Eva Hesius, Charlotte M de Winde, Michiel Vermeulen, Michiel van den Brand, Blanca Scheijen, Annemiek van Spriel

Journal: Blood Adv

PubMed ID: 35086136

Doi: 10.1182/bloodadvances.2021004366

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Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Authors: Diego Angosto-Bazarra, Cristina Alarcón-Vila, Laura Hurtado-Navarro, María C Baños, Jack Rivers-Auty, Pablo Pelegrín

Journal: BMC Biol

PubMed ID: 34996441

Doi: 10.1186/s12915-021-01220-z

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Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden

Authors: Julia Femel, Luuk van Hooren, Melanie Herre, Jessica Cedervall, Falk Saupe, Elisabeth J M Huijbers, Danielle R J Verboogen, Matthias Reichel, Victor L Thijssen, Arjan W Griffioen, Lars Hellman, Anna Dimberg, Anna-Karin Olsson

Journal: Cancer Immunol Immunother

PubMed ID: 35018481

Doi: 10.1007/s00262-021-03139-4

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Experimental Periodontitis Deteriorated Atherosclerosis Associated With Trimethylamine N-Oxide Metabolism in Mice

Authors: Lingling Xiao, Lingyan Huang, Xin Zhou, Dan Zhao, Yan Wang, Haiyan Min, Shiyu Song, Weibin Sun, Qian Gao, Qingang Hu, Sijing Xie

Journal: Front Cell Infect Microbiol

PubMed ID: 35118014

Doi: 10.3389/fcimb.2021.820535

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Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening

Authors: Meghan J O'Melia, Adriana Mulero-Russe, Jihoon Kim, Alyssa Pybus, Deborah DeRyckere, Levi Wood, Douglas K Graham, Edward Botchwey, Andrés J García, Susan N Thomas

Journal: Adv Mater

PubMed ID: 34989049

Doi: 10.1002/adma.202108084

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RIPPA: Identification of MHC-II Binding Peptides from Antigen Using a Yeast Display-Based Approach

Authors: Rongzeng Liu, Wei Jiang, Ying Li, Elizabeth D Mellins

Journal: Curr Protoc

PubMed ID: 35041265

Doi: 10.1002/cpz1.350

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Antigenic and immunogenic properties of recombinant proteins consisting of two immunodominant African swine fever virus proteins fused with bacterial lipoprotein OprI

Authors: Guanglei Zhang, Wei Liu, Zhan Gao, Yanyan Chang, Sicheng Yang, Qian Peng, Sudan Ge, Bijing Kang, Junjun Shao, Huiyun Chang

Journal: Virol J

PubMed ID: 35062983

Doi: 10.1186/s12985-022-01747-9

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Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study

Authors: Layaly Shkair, Ekaterina Evgenevna Garanina, Ekaterina Vladimirovna Martynova, Alena Igorevna Kolesnikova, Svetlana Sergeevna Arkhipova, Angelina Andreevna Titova, Albert Anatolevich Rizvanov, Svetlana Francevna Khaiboullina

Journal: Pharmaceutics

PubMed ID: 35056989

Doi: 10.3390/pharmaceutics14010093

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Improving one-step scarless genome editing in by combining co-CRISPR selection with sgRNA target site masking

Authors: Katharina J Götze, Achmed Mrestani, Paula Beckmann, Knut Krohn, Diana Le Duc, Akhil Velluva, Mathias A Böhme, Manfred Heckmann, Rami Abou Jamra, Johannes R Lemke, Hendrik Bläker, Nicole Scholz, Dmitrij Ljaschenko, Tobias Langenhan

Journal: Biol Methods Protoc

PubMed ID: 35087953

Doi: 10.1093/biomethods/bpac003

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The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities

Authors: Raffaele Iennaco, Giulio Formenti, Camilla Trovesi, Riccardo Lorenzo Rossi, Chiara Zuccato, Tiziana Lischetti, Vittoria Dickinson Bocchi, Andrea Scolz, Cristina Martínez-Labarga, Olga Rickards, Michela Pacifico, Angelica Crottini, Anders Pape Møller, Richard Zhenghuan Chen, Thomas Francis Vogt, Giulio Pavesi, David Stephen Horner, Nicola Saino, Elena Cattaneo

Journal: Cell Death Differ

PubMed ID: 34974533

Doi: 10.1038/s41418-021-00914-9

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Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids

Authors: Icaro Putinhon Caruso, Vitor Dos Santos Almeida, Mariana Juliani do Amaral, Guilherme Caldas de Andrade, Gabriela Rocha de Araújo, Talita Stelling de Araújo, Jéssica Moreira de Azevedo, Glauce Moreno Barbosa, Leonardo Bartkevihi, Peter Reis Bezerra, Katia Maria Dos Santos Cabral, Isabella Otênio de Lourenço, Clara L F Malizia-Motta, Aline de Luna Marques, Nathane Cunha Mebus-Antunes, Thais Cristtina Neves-Martins, Jéssica Maróstica de Sá, Karoline Sanches, Marcos Caique Santana-Silva, Ariana Azevedo Vasconcelos, Marcius da Silva Almeida, Gisele Cardoso de Amorim, Cristiane Dinis Anobom, Andrea T Da Poian, Francisco Gomes-Neto, Anderson S Pinheiro, Fabio C L Almeida

Journal: Int J Biol Macromol

PubMed ID: 35077748

Doi: 10.1016/j.ijbiomac.2022.01.121

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A Palette of Fluorescent A42 Peptides Labelled at a Range of Surface-Exposed Sites

Authors: Dev Thacker, Mara Bless, Mohammad Barghouth, Enming Zhang, Sara Linse

Journal: Int J Mol Sci

PubMed ID: 35163577

Doi: 10.3390/ijms23031655

Products & Services: Bacterial Expression

Activation of the plant mevalonate pathway by extracellular ATP

Authors: Sung-Hwan Cho, Katalin Tóth, Daewon Kim, Phuc H Vo, Chung-Ho Lin, Pubudu P Handakumbura, Albert Rivas Ubach, Sterling Evans, Ljiljana Paša-Tolić, Gary Stacey

Journal: Nat Commun

PubMed ID: 35064110

Doi: 10.1038/s41467-022-28150-w

Products & Services: Protein and Antibody Isolation

Recognition and Chaperoning by Pex19, Followed by Trafficking and Membrane Insertion of the Peroxisome Proliferation Protein, Pex11

Authors: Katarzyna M Zientara-Rytter, Shanmuga S Mahalingam, Jean-Claude Farré, Krypton Carolino, Suresh Subramani

Journal: Cells

PubMed ID: 35011719

Doi: 10.3390/cells11010157

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The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a

Authors: Luiza Mamigonian Bessa, Serafima Guseva, Aldo R Camacho-Zarco, Nicola Salvi, Damien Maurin, Laura Mariño Perez, Maiia Botova, Anas Malki, Max Nanao, Malene Ringkjøbing Jensen, Rob W H Ruigrok, Martin Blackledge

Journal: Sci Adv

PubMed ID: 35044811

Doi: 10.1126/sciadv.abm4034

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Minc03328 effector gene downregulation severely affects Meloidogyne incognita parasitism in transgenic Arabidopsis thaliana

Authors: Valdeir Junio Vaz Moreira, Isabela Tristan Lourenço-Tessutti, Marcos Fernando Basso, Maria Eugênia Lisei-de-Sa, Carolina Vianna Morgante, Bruno Paes-de-Melo, Fabrício Barbosa Monteiro Arraes, Diogo Martins-de-Sa, Maria Cristina Mattar Silva, Janice de Almeida Engler, Maria Fatima Grossi-de-Sa

Journal: Planta

PubMed ID: 35050413

Doi: 10.1007/s00425-022-03823-4

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Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex

Authors: Sunesh Sethumadhavan, Marie Barth, Robbert M Spaapen, Carla Schmidt, Simon Trowitzsch, Robert Tampé

Journal: Sci Rep

PubMed ID: 35087068

Doi: 10.1038/s41598-022-05000-9

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Long-Term High-Fat Diet Consumption Depletes Glial Cells and Tyrosine Hydroxylase-Containing Neurons in the Brain of Middle-Aged Rats

Authors: Mei-Chuan Chou, Hsiang-Chun Lee, Yen-Chin Liu, Patrick Szu-Ying Yen, Ching-Kuan Liu, Chu-Huang Chen, Tzu-Han Hsieh, Shiou-Lan Chen

Journal: Cells

PubMed ID: 35053411

Doi: 10.3390/cells11020295

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Development of Peptide Targeted PLGA-PEGylated Nanoparticles Loading Licochalcone-A for Ocular Inflammation

Authors: Ruth Galindo, Elena Sánchez-López, María José Gómara, Marta Espina, Miren Ettcheto, Amanda Cano, Isabel Haro, Antoni Camins, María Luisa García

Journal: Pharmaceutics

PubMed ID: 35214019

Doi: 10.3390/pharmaceutics14020285

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Fifty Shades of E: Innate Immune Evasion by the Viral Endonucleases of All Pestivirus Species

Authors: Elena de Martin, Matthias Schweizer

Journal: Viruses

PubMed ID: 35215858

Doi: 10.3390/v14020265

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Cardiac troponin T and autoimmunity in skeletal muscle aging

Authors: Tan Zhang, Xin Feng, Juan Dong, Zherong Xu, Bo Feng, Karen M Haas, Peggy M Cawthon, Kristen M Beavers, Barbara Nicklas, Stephen Kritchevsky

Journal: Geroscience

PubMed ID: 35034279

Doi: 10.1007/s11357-022-00513-7

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CRISPR guides induce gene silencing in plants in the absence of Cas

Authors: Veerendra Kumar Sharma, Sandeep Marla, Wenguang Zheng, Divya Mishra, Jun Huang, Wei Zhang, Geoffrey Preston Morris, David Edward Cook

Journal: Genome Biol

PubMed ID: 34980227

Doi: 10.1186/s13059-021-02586-7

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De Novo Transcriptome of (Cactaceae) under In Vitro Conditions and Identification of Glyoxalase Genes

Authors: Carolina Enríquez-González, Cristina Garcidueñas-Piña, Osvaldo Adrián Castellanos-Hernández, Sergio Enríquez-Aranda, Abraham Loera-Muro, Gilberto Ocampo, Eugenio Pérez-Molphe Balch, José Francisco Morales-Domínguez

Journal: Plants (Basel)

PubMed ID: 35161380

Doi: 10.3390/plants11030399

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Objective to identify and verify the regulatory mechanism of DTNBP1 as a prognostic marker for hepatocellular carcinoma

Authors: Xianyi Cheng, Dezhi Li, Tiangyang Qi, Jia Sun, Tao Zhou, Wei V Zheng

Journal: Sci Rep

PubMed ID: 34997064

Doi: 10.1038/s41598-021-04055-4

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Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

Authors: Wei Shi, Lingshu Wang, Tongqing Zhou, Mallika Sastry, Eun Sung Yang, Yi Zhang, Man Chen, Xuejun Chen, Misook Choe, Adrian Creanga, Kwan Leung, Adam S Olia, Amarendra Pegu, Reda Rawi, Chen-Hsiang Shen, Erik-Stephane D Stancofski, Chloe Adrienna Talana, I-Ting Teng, Shuishu Wang, Kizzmekia S Corbett, Yaroslav Tsybovsky, John R Mascola, Peter D Kwong

Journal: biorxiv

PubMed ID: 35118472

Doi: 10.1101/2022.01.25.477770

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Three Specific Potential Epitopes That Could Be Recognized by T Cells of Convalescent COVID-19 Patients Were Identified From Spike Protein

Authors: Yunwen Zhang, Zhengrong Yang, Mingyuan Tang, Hao Li, Tian Tang, Guilian Li, Yifan Zhong, Xiaomin Zhang, Xiaohui Wang, Chuan Wang

Journal: Front Immunol

PubMed ID: 35154095

Doi: 10.3389/fimmu.2022.752622

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Single-conformation spectroscopy of cold, protonated PG-containing peptides: switching β-turn types and formation of a sequential type II/II' double β-turn

Authors: John T Lawler, Christopher P Harrilal, Andrew F DeBlase, Edwin L Sibert, Scott A McLuckey, Timothy S Zwier

Journal: Phys Chem Chem Phys

PubMed ID: 35019911

Doi: 10.1039/d1cp04852j

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A murine Skint6 W168X allele contributes to autoimmune disease in a transgenic model

Authors: Jiyu Ju, Hui Wang, Meng Lian, Yatao Bao, Yanyan Zhang, Zhiwei Xu

Journal: Lupus

PubMed ID: 35045734

Doi: 10.1177/09612033221074544

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Comprehensive engineering of a therapeutic neutralizing antibody targeting SARS-CoV-2 spike protein to neutralize escape variants

Authors: Taichi Kuramochi, Siok Wan Gan, Adrian W S Ho, Bei Wang, Nagisa Kageji, Takeru Nambu, Sayaka Iida, Momoko Okuda-Miura, Wei Shan Chia, Chiew Ying Yeo, Dan Chen, Wen-Hsin Lee, Eve Zi Xian Ngoh, Siti Nazihah Mohd Salleh, Cheng-I Wang, Tomoyuki Igawa, Hideaki Shimada

Journal: MAbs

PubMed ID: 35293276

Doi: 10.1080/19420862.2022.2040350

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USF1 Transcriptionally Regulates UGT1A3 and Promotes Lung Adenocarcinoma Progression by Regulating Neurotrophin Signaling Pathway

Authors: Yu Wang, Yun-Xia Zhao, Xiang-Wei Zhang, Yuan-Zhu Jiang, Wei Ma, Lin Zhang, Wei Dong

Journal: Front Mol Biosci

PubMed ID: 35155573

Doi: 10.3389/fmolb.2022.758968

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Ion currents through Kir potassium channels are gated by anionic lipids

Authors: Ruitao Jin, Sitong He, Katrina A Black, Oliver B Clarke, Di Wu, Jani R Bolla, Paul Johnson, Agalya Periasamy, Ahmad Wardak, Peter Czabotar, Peter M Colman, Carol V Robinson, Derek Laver, Brian J Smith, Jacqueline M Gulbis

Journal: Nat Commun

PubMed ID: 35079013

Doi: 10.1038/s41467-022-28148-4

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Covalent coupling of Spike's receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2

Authors:

Journal: Sci Rep

PubMed ID: 35027583

Doi: 10.1038/s41598-021-03675-0

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Rapid sequence evolution is associated with genetic incompatibilities in the plastid Clp complex

Authors: Salah E Abdel-Ghany, Lisa M LaManna, Haleakala T Harroun, Pal Maliga, Daniel B Sloan

Journal: Plant Mol Biol

PubMed ID: 35039977

Doi: 10.1007/s11103-022-01241-4

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DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3

Authors: Feng Hu, Ki On Fong, May Pui Lai Cheung, Jessica Aijia Liu, Rui Liang, Tsz Wai Li, Rakesh Sharma, Philip Pun-Ching Ip, Xintao Yang, Martin Cheung

Journal: Adv Sci (Weinh)

PubMed ID: 35088579

Doi: 10.1002/advs.202105226

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Genome-wide characterization of Histone gene family and expression profiling during microspore development in radish (Raphanus sativus L)

Authors: Qijiao Wang, Lianxue Fan, Xiaojun Su, Jiali Ying, Liang Xu, Cui Li, Yan Wang, Liwang Liu

Journal: Gene

PubMed ID: 34990794

Doi: 10.1016/j.gene.2021.146180

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Isoforms of the neuropeptide myosuppressin differentially modulate the cardiac neuromuscular system of the American lobster,

Authors: Emily R Oleisky, Meredith E Stanhope, J Joe Hull, Patsy S Dickinson

Journal: J Neurophysiol

PubMed ID: 35044860

Doi: 10.1152/jn.00338.2021

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Elucidating the 3D Structure of a Surface Membrane Antigen from as a Serodiagnostic Biomarker of Chagas Disease

Authors: Flavio Di Pisa, Stefano De Benedetti, Enrico Mario Alessandro Fassi, Mauro Bombaci, Renata Grifantini, Angelo Musicò, Roberto Frigerio, Angela Pontillo, Cinzia Rigo, Sandra Abelli, Romualdo Grande, Nadia Zanchetta, Davide Mileto, Alessandro Mancon, Alberto Rizzo, Alessandro Gori, Marina Cretich, Giorgio Colombo, Martino Bolognesi, Louise Jane Gourlay

Journal: Vaccines (Basel)

PubMed ID: 35062732

Doi: 10.3390/vaccines10010071

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The ectomycorrhizal basidiomycete Laccaria bicolor releases a GH28 polygalacturonase that plays a key role in symbiosis establishment

Authors: Feng Zhang, Aurore Labourel, Mireille Haon, Minna Kemppainen, Emilie Da Silva Machado, Nicolas Brouilly, Claire Veneault-Fourrey, Annegret Kohler, Marie-Noëlle Rosso, Alejandro Pardo, Bernard Henrissat, Jean-Guy Berrin, Francis Martin

Journal: New Phytol

PubMed ID: 34942023

Doi: 10.1111/nph.17940

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Mechanism of MyD88S mediated signal termination

Authors: Katarzyna Pustelny, Katarzyna Kuska, Andrzej Gorecki, Bogdan Musielak, Ewelina Dobosz, Benedykt Wladyka, Joanna Koziel, Anna Czarna, Tad Holak, Grzegorz Dubin

Journal: Cell Commun Signal

PubMed ID: 35057808

Doi: 10.1186/s12964-021-00811-1

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Target-Based Virtual Screening and LC/MS-Guided Isolation Procedure for Identifying Phloroglucinol-Terpenoid Inhibitors of SARS-CoV-2

Authors: Bo Hou, Yu-Min Zhang, Han-Yi Liao, Li-Feng Fu, De-Dong Li, Xin Zhao, Jian-Xun Qi, Wei Yang, Geng-Fu Xiao, Lian Yang, Zheng-Yu Zuo, Lin Wang, Xiang-Lei Zhang, Fang Bai, Liu Yang, George F Gao, Hao Song, Jiang-Miao Hu, Wei-Juan Shang, Jun Zhou

Journal: J Nat Prod

PubMed ID: 35084181

Doi: 10.1021/acs.jnatprod.1c00805

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Discovery of Fragment-Based Inhibitors of SARS-CoV 2 PL Pro

Authors: Qiangqiang Wei; Ashley J. Taylor; Mahesh Angadrao Barmade; Kevin B. Teuscher; Somanath Chowdhury; Chideraa Apakama; Jordan Anderson-Daniels; Zhu Yongqing; David C. Schultz; Tyson A. Rietz; Taylor M. South; Mackenzie M. Crow; Bin Zhao; Kangsa Amporndanai; John L. Sensintaffar; Jason Phan; Sara Cherry; Mark Denison; Taekyu Lee; Stephen W. Fesik

Journal: Journal of Medicinal Chemistry

PubMed ID: 41521555

Doi: 10.1021/acs.jmedchem.5c02832

A dual regulatory circuit consisting of S -adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei

Authors: Manish M. Patel; Oleg A. Volkov; Christopher Leija; Andrew Lemoff; Margaret A. Phillips

Journal: PLOS Pathogens

PubMed ID: 30365568

Doi: 10.1371/journal.ppat.1007404

Discovery of Fragment-Based Inhibitors of SARS-CoV 2 PL Pro

Journal: Journal of Medicinal Chemistry

PubMed ID: 41521555

Doi: 10.1021/acs.jmedchem.5c02832

The First FRET-Based RNA Aptamer NanoKit for Sensitively and Specifically Detecting c-di-GMP

Authors: Ya Gao , Yurui Xu , Yanyan Li , Kerong Chen , Xiaotong Wu , Yuhang Liu , Xuli Feng , Desheng Kong , Xinghai Ning

Journal: Nano Lett

PubMed ID: 34994567

Doi: 10.1021/acs.nanolett.1c03970

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Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

Authors: Algirdas Grevys, Rahel Frick, Simone Mester, Karine Flem-Karlsen, Jeannette Nilsen, Stian Foss, Kine Marita Knudsen Sand, Thomas Emrich, Jens Andre Alexander Fischer, Victor Greiff, Inger Sandlie, Tilman Schlothauer, Jan Terje Andersen

Journal: iScience

PubMed ID: 35118359

Doi: 10.1016/j.isci.2022.103746

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CRISPR/Cas12a Technology Combined With RPA for Rapid and Portable SFTSV Detection

Authors: Mengqian Huang, Sihua Liu, Yanan Xu, Aqian Li, Wei Wu, Mifang Liang, Guoyu Niu, Zhiyun Wang, Tao Wang

Journal: Front Microbiol

PubMed ID: 35145502

Doi: 10.3389/fmicb.2022.754995

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A network of Gα signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF

Authors: Naincy R Chandan, Saji Abraham, Shuvasree SenGupta, Carole A Parent, Alan V Smrcka

Journal: Sci Signal

PubMed ID: 35041463

Doi: 10.1126/scisignal.abi9869

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Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma

Authors: Sofie Kirial Mørk, Mohammad Kadivar, Kalijn Fredrike Bol, Arianna Draghi, Marie Christine Wulff Westergaard, Signe Koggersbøl Skadborg, Nana Overgaard, Anders Bundgård Sørensen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Christina Westmose Yde, Thomas Trolle, Christian Garde, Jens Friis-Nielsen, Nis Nørgaard, Dennis Christensen, Jens Vindahl Kringelum, Marco Donia, Sine Reker Hadrup, Inge Marie Svane

Journal: Oncoimmunology

PubMed ID: 35036074

Doi: 10.1080/2162402X.2021.2023255

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Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide

Authors: Nathalie Vanderheijden, Annelies Stevaert, Jiexiong Xie, Xiaolei Ren, Cyril Barbezange, Sam Noppen, Isabelle Desombere, Bruno Verhasselt, Peter Geldhof, Nick Vereecke, Veerle Stroobants, Dayoung Oh, Merijn Vanhee, Lieve M J Naesens, Hans J Nauwynck

Journal: Front Immunol

PubMed ID: 35069571

Doi: 10.3389/fimmu.2021.790415

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Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance

Authors: Gabriel Therizols, Zeina Bash-Imam, Baptiste Panthu, Christelle Machon, Anne Vincent, Julie Ripoll, Sophie Nait-Slimane, Mounira Chalabi-Dchar, Angéline Gaucherot, Maxime Garcia, Florian Laforêts, Virginie Marcel, Jihane Boubaker-Vitre, Marie-Ambre Monet, Céline Bouclier, Christophe Vanbelle, Guillaume Souahlia, Elise Berthel, Marie Alexandra Albaret, Hichem C Mertani, Michel Prudhomme, Martin Bertrand, Alexandre David, Jean-Christophe Saurin, Philippe Bouvet, Eric Rivals, Théophile Ohlmann, Jérôme Guitton, Nicole Dalla Venezia, Julie Pannequin, Frédéric Catez, Jean-Jacques Diaz

Journal: Nat Commun

PubMed ID: 35013311

Doi: 10.1038/s41467-021-27847-8

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CD46 Isoforms Influence the Mode of Entry by Human Herpesvirus 6A/B in T Cells

Authors: Litten Sørensen Rossen, Vivien R Schack, Katrine Kyd Holstein Thuesen, Bettina Bundgaard, Per Höllsberg

Journal: J Virol

PubMed ID: 35019717

Doi: 10.1128/JVI.01557-21

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