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Rice stripe virus activates the bZIP17/28 branch of the unfolded protein response signalling pathway to promote viral infection

Authors: Chenyang Li, Tianze Zhang, Yu Liu, Zongdi Li, Yaqin Wang, Shuai Fu, Yi Xu, Tong Zhou, Jianxiang Wu, Xueping Zhou

Journal: Mol Plant Pathol

PubMed ID: 34897936

Doi: 10.1111/mpp.13171

Products & Services: Catalog Antibodies

GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1

Authors: Lucia Balazova, Miroslav Balaz, Carla Horvath, Áron Horváth, Caroline Moser, Zuzana Kovanicova, Adhideb Ghosh, Umesh Ghoshdastider, Vissarion Efthymiou, Elke Kiehlmann, Wenfei Sun, Hua Dong, Lianggong Ding, Ez-Zoubir Amri, Pirjo Nuutila, Kirsi A Virtanen, Tarja Niemi, Barbara Ukropcova, Jozef Ukropec, Pawel Pelczar, Thorsten Lamla, Bradford Hamilton, Heike Neubauer, Christian Wolfrum

Journal: Nat Commun

PubMed ID: 34880217

Doi: 10.1038/s41467-021-27442-x

Products & Services: Mammalian Expression

RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation

Authors: Fabian Poetz, Joshua Corbo, Yevgen Levdansky, Alexander Spiegelhalter, Doris Lindner, Vera Magg, Svetlana Lebedeva, Jörg Schweiggert, Johanna Schott, Eugene Valkov, Georg Stoecklin

Journal: Nat Commun

PubMed ID: 34887419

Doi: 10.1038/s41467-021-27471-6

Products & Services: Gene Fragments

Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

Authors: Yukiko Sato, Kamila R Mustafina, Yishan Luo, Carolina Martini, David Y Thomas, Paul W Wiseman, John W Hanrahan

Journal: Sci Rep

PubMed ID: 34853321

Doi: 10.1038/s41598-021-02420-x

Products & Services: Plasmid DNA Preparation

Expression profile of RNA binding protein in cervical cancer using bioinformatics approach

Authors: Zhiyuan Huang, Fang Li, Qinchuan Li

Journal: Cancer Cell Int

PubMed ID: 34863153

Doi: 10.1186/s12935-021-02319-7

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Soybean miR159 Regulatory Network Involved in Gibberellin-Modulated Resistance to

Authors: Piao Lei, Nawei Qi, Yuan Zhou, Yuanyuan Wang, Xiaofeng Zhu, Yuanhu Xuan, Xiaoyu Liu, Haiyan Fan, Lijie Chen, Yuxi Duan

Journal: Int J Mol Sci

PubMed ID: 34884977

Doi: 10.3390/ijms222313172

Products & Services: Protein and Antibody Isolation

Non-β-blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

Authors: Caroline T Seebauer, Matthew S Graus, Lan Huang, Alex J McCann, Jill Wylie-Sears, Frank R Fontaine, Tara Karnezis, David Zurakowski, Steven J Staffa, Frédéric A Meunier, John B Mulliken, Joyce Bischoff, Mathias Francois

Journal: J Clin Invest

PubMed ID: 34874911

Doi: 10.1172/JCI151109

Products & Services: ORF cDNA Clones/MolecularCloud

Rhomboid-like Protein 5 Provided Partial Protection against Homologous Challenge in Forms of Recombinant Protein and DNA Plasmid in Chickens

Authors: Di Tian, Xiaoqian Liu, Xiangrui Li, Lixin Xu, Ruofeng Yan, Xiaokai Song

Journal: Vaccines (Basel)

PubMed ID: 35062693

Doi: 10.3390/vaccines10010032

Products & Services: Endotoxin Detection & Removal System

Bak and Bcl-xL Participate in Regulating Sensitivity of Solid Tumor Derived Cell Lines to Mcl-1 Inhibitors

Authors: Viacheslav V Senichkin, Nikolay V Pervushin, Alexey V Zamaraev, Elena V Sazonova, Anton P Zuev, Alena Y Streletskaia, Tatiana A Prikazchikova, Timofei S Zatsepin, Olga V Kovaleva, Elena M Tchevkina, Boris Zhivotovsky, Gelina S Kopeina

Journal: Cancers (Basel)

PubMed ID: 35008345

Doi: 10.3390/cancers14010181

Products & Services: Plasmid DNA Preparation

Comparison of SARS-CoV-2 Antibody Response 4 Weeks After Homologous vs Heterologous Third Vaccine Dose in Kidney Transplant Recipients: A Randomized Clinical Trial

Authors: Roman Reindl-Schwaighofer, Andreas Heinzel, Manuel Mayrdorfer, Rhea Jabbour, Thomas M Hofbauer, Anne Merrelaar, Michael Eder, Florina Regele, Konstantin Doberer, Paul Spechtl, Constantin Aschauer, Maximilian Koblischke, Christopher Paschen, Farsad Eskandary, Karin Hu, Barbara Öhler, Arshdeep Bhandal, Sabine Kleibenböck, Rahel I Jagoditsch, Bianca Reiskopf, Florian Heger, Gregor Bond, Georg A Böhmig, Robert Strassl, Lukas Weseslindtner, Alexander Indra, Judith H Aberle, Michael Binder, Rainer Oberbauer

Journal: JAMA Intern Med

PubMed ID: 34928302

Doi: 10.1001/jamainternmed.2021.7372

Products & Services: Protein and Antibody Reagents

Development of competitive and noncompetitive immunoassays for clothianidin with high sensitivity and specificity using phage-displayed peptides

Authors: Tianyang You, Yuan Ding, He Chen, Guangyue Song, Lianrun Huang, Minghua Wang, Xiude Hua

Journal: J Hazard Mater

PubMed ID: 34896720

Doi: 10.1016/j.jhazmat.2021.128011

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A New Testing Platform Using Fingerstick Blood for Quantitative Antibody Response Evaluation after SARS-CoV-2 Vaccination

Authors: Jinwei Du, Dayu Zhang, Joseph A Pathakamuri, Daniel Kuebler, Ying Yang, Yulia Loginova, Eric Chu, Roberta Madej, Jocelyn V Neves, Brianna Singer, Holly Radke, Naomi Spencer, Elizabeth Rizk, Aiguo Zhang, Chuanyi M Lu, Michael Y Sha

Journal: Emerg Microbes Infect

PubMed ID: 34951566

Doi: 10.1080/22221751.2021.2023328

Products & Services: Protein and Antibody Reagents

Rapid directed molecular evolution of fluorescent proteins in mammalian cells

Authors: Siranush Babakhanova, Erica E Jung, Kazuhiko Namikawa, Hanbin Zhang, Yangdong Wang, Oksana M Subach, Dmitry A Korzhenevskiy, Tatiana V Rakitina, Xian Xiao, Wenjing Wang, Jing Shi, Mikhail Drobizhev, Demian Park, Lea Eisenhard, Hongyun Tang, Reinhard W Köster, Fedor V Subach, Edward S Boyden, Kiryl D Piatkevich

Journal: Protein Sci

PubMed ID: 34913537

Doi: 10.1002/pro.4261

Products & Services: Gene Synthesis

Selective suppression of IL-10 transcription by calcineurin in dendritic cells through inactivation of CREB

Authors: Xiuyuan Lu, Masatsugu Oh-Hora, Kiyoshi Takeda, Sho Yamasaki

Journal: Int Immunol

PubMed ID: 34953165

Doi: 10.1093/intimm/dxab112

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Simplified Point-of-Care Full SARS-CoV-2 Genome Sequencing Using Nanopore Technology

Authors: Anton Pembaur, Erwan Sallard, Patrick Philipp Weil, Jennifer Ortelt, Parviz Ahmad-Nejad, Jan Postberg

Journal: Microorganisms

PubMed ID: 34946199

Doi: 10.3390/microorganisms9122598

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Induction of Th1 and Th2 in the protection against SARS-CoV-2 through mucosal delivery of an adenovirus vaccine expressing an engineered spike protein

Authors: Nai-Hsiang Chung, Ying-Chin Chen, Shiu-Ju Yang, Yu-Ching Lin, Horng-Yunn Dou, Lily Hui-Ching Wang, Ching-Len Liao, Yen-Hung Chow

Journal: Vaccine

PubMed ID: 34952759

Doi: 10.1016/j.vaccine.2021.12.024

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SARS-CoV-2 recombinant proteins stimulate distinct cellular and humoral immune response profiles in samples from COVID-19 convalescent patients

Authors: Laís Teodoro da Silva, Marina Mazzilli Ortega, Bruna Tiaki Tiyo, Isabelle Freire Tabosa Viana, Tayná Evily de Lima, Tania Regina Tozetto-Mendoza, Luanda Mara da Silva Oliveira, Franciane Mouradian Emidio Teixeira, Roberto Dias Lins, Alexandre de Almeida, Maria Cassia Mendes-Correa, Alberto Jose da Silva Duarte, Telma Miyuki Oshiro

Journal: Clinics (Sao Paulo)

PubMed ID: 34878034

Doi: 10.6061/clinics/2021/e3548

Products & Services: Protein and Antibody Reagents

Porcine Genome-Wide CRISPR Screen Identifies the Golgi Apparatus Complex Protein COG8 as a Pivotal Regulator of Influenza Virus Infection

Authors: Ao Zhou, Wenhua Zhang, Xia Dong, Bin Tang

Journal: CRISPR J

PubMed ID: 34935491

Doi: 10.1089/crispr.2021.0054

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Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion

Authors: Taimoor H Qazi, Jingyu Wu, Victoria G Muir, Shoshana Weintraub, Sarah E Gullbrand, Daeyeon Lee, David Issadore, Jason A Burdick

Journal: Adv Mater

PubMed ID: 34932833

Doi: 10.1002/adma.202109194

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Bio inspired growth factor loaded self assembling peptide nano hydrogel for chronic wound healing

Authors: E Santhini, R Parthasarathy, M Shalini, S Dhivya, L Amalorpava Mary, V Vijaya Padma

Journal: Int J Biol Macromol

PubMed ID: 34920072

Doi: 10.1016/j.ijbiomac.2021.12.026

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Chromosome-specific painting unveils chromosomal fusions and distinct allopolyploid species in the Saccharum complex

Authors: Fan Yu, Xinwang Zhao, Jin Chai, Xueer Ding, Xueting Li, Yongji Huang, Xianhong Wang, Jiayun Wu, Muqing Zhang, Qinghui Yang, Zuhu Deng, Jiming Jiang

Journal: New Phytol

PubMed ID: 34874076

Doi: 10.1111/nph.17905

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Ndufa6 regulates adipogenic differentiation via Scd1

Authors: Jingwei Zhang, Wei Wang, Ninghan Feng, Xuan Jiang, Shenglong Zhu, Yong Q Chen

Journal: Adipocyte

PubMed ID: 34793269

Doi: 10.1080/21623945.2021.2007590

Products & Services: Recombinant Proteins

Circular RNA erythrocyte membrane protein band 41 assuages ultraviolet irradiation-induced apoptosis of lens epithelial cells by stimulating 5'-bisphosphate nucleotidase 1 in a miR-24-3p-dependent manner

Authors: Cuiyun Zhou, Xiaoqiong Huang, Xia Li, Yan Xiong

Journal: Bioengineered

PubMed ID: 34652259

Doi: 10.1080/21655979.2021.1990196

Products & Services: Protein Electrophoresis and Western

Transcription factor specificity protein 1-mediated Serine/threonine kinase 39 upregulation promotes the proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells by activating the transforming growth factor-β1 /Smad2/3 pathway

Authors: Jing Wang, Zhenyu Fan, Jia Li, Jingmao Yang, Xiaofei Liu, Jilin Cheng

Journal: Bioengineered

PubMed ID: 34281492

Doi: 10.1080/21655979.2021.1947939

Products & Services: Protein and Antibody Isolation

Correction to: Expanding the Genetic and Phenotypic Spectrum of Female Infertility Caused by TUBB8 Mutations

Authors: Qianneng Lu, Xiaolan Zhang, Qiqi Cao, Congjing Wang, Jie Ding, Chun Zhao, Junqiang Zhang, Xiufeng Ling, Qingxia Meng, Ran Huo, Hong Li

Journal: Reprod Sci

PubMed ID: 34542892

Doi: 10.1007/s43032-021-00742-9

Products & Services: DNA Sequencing

Melatonin protects H9c2 cardiomyoblasts from oxygen glucose deprivation and reperfusion-induced injury by inhibiting Rac1/JNK/Foxo3a/Bim signaling pathway

Authors: Yulin Wang, Ying Jian, Xiaofu Zhang, Bin Ni, Mingwei Wang, Chunqi Pan

Journal: Cell Biol Int

PubMed ID: 34882903

Doi: 10.1002/cbin.11739

Products & Services: Custom Vector Construction

Enhancing the detection sensitivity of nanobody against aflatoxin B through structure-guided modification

Authors: Ting He, Yao Nie, Tingting Yan, Jiang Zhu, Xiaoling He, Ying Li, Qi Zhang, Xiaoqian Tang, Rui Hu, Yunhuang Yang, Maili Liu

Journal: Int J Biol Macromol

PubMed ID: 34863829

Doi: 10.1016/j.ijbiomac.2021.11.182

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Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials

Authors: Gang Zeng, Qianhui Wu, Hongxing Pan, Minjie Li, Juan Yang, Lin Wang, Zhiwei Wu, Deyu Jiang, Xiaowei Deng, Kai Chu, Wen Zheng, Lei Wang, Wanying Lu, Bihua Han, Yuliang Zhao, Fengcai Zhu, Hongjie Yu, Weidong Yin

Journal: Lancet Infect Dis

PubMed ID: 34890537

Doi: 10.1016/S1473-3099(21)00681-2

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A new self-attenuated therapeutic influenza vaccine that uses host cell-restricted attenuation by artificial microRNAs

Authors: Ke Wen, Haiyan Wang, Yanping Chen, Huixiao Yang, Zhichao Zheng, Yongyong Yan, Realivazquez Adilene, Mingtao Zeng

Journal: Int J Pharm

PubMed ID: 34883209

Doi: 10.1016/j.ijpharm.2021.121325

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Cloning and functional identification of setaria italica somatic embryogenesis receptor-like kinase1 gene (SiSERK1)

Authors: Guofan Wu, Wenbo Li, Nongfu Tian, Xin Wang, Wangze Wu, Sheng Zheng

Journal: Gene

PubMed ID: 34902513

Doi: 10.1016/j.gene.2021.146119

Products & Services: Protein and Antibody Isolation

Motif-driven protein binder design towards transferrin receptor helical domain

Authors: Dick J Sjöström, Camilla Mohlin, Elena Ambrosetti, Scott J Garforth, Ana I Teixeira, Sinisa Bjelic

Journal: FEBS J

PubMed ID: 34862739

Doi: 10.1111/febs.16311

Products & Services: Protein and Antibody Isolation

Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

Authors: Moustafa T Mabrouk, Kevin Chiem, Edurne Rujas, Wei-Chiao Huang, Dushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H Nissly, Victoria S Cavener, Nina R Boyle, Ty A Sornberger, Suresh V Kuchipudi, Joaquin Ortega, Jean-Philippe Julien, Luis Martinez-Sobrido, Jonathan Lovell

Journal: Sci Adv

PubMed ID: 34851667

Doi: 10.1126/sciadv.abj1476

Products & Services: Protein and Antibody Isolation

Antifungal activity and mode of action of synthetic peptides derived from the tick OsDef2 defensin

Authors: Kabuzi R Mbuayama, Helena Taute, Adam A Strӧmstedt, Megan J Bester, Anabella R M Gaspar

Journal: J Pept Sci

PubMed ID: 34866278

Doi: 10.1002/psc.3383

Products & Services: Peptide Synthesis

Barcoded reciprocal hemizygosity analysis via sequencing illuminates the complex genetic basis of yeast thermotolerance

Authors: Melanie B Abrams, Julie N Chuong, Faisal AlZaben, Claire A Dubin, Jeffrey M Skerker, Rachel B Brem

Journal: G3 (Bethesda)

PubMed ID: 34878132

Doi: 10.1093/g3journal/jkab412

Products & Services: Protein and Antibody Isolation

Architecture of the chloroplast PSI-NDH supercomplex in Hordeum vulgare

Authors: Liangliang Shen, Kailu Tang, Wenda Wang, Chen Wang, Hangjun Wu, Zhiyuan Mao, Shaoya An, Shenghai Chang, Tingyun Kuang, Jian-Ren Shen, Guangye Han, Xing Zhang

Journal: Nature

PubMed ID: 34879391

Doi: 10.1038/s41586-021-04277-6

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Construction, expression, purification, characterization, and structural analysis of microbial transglutaminase variants

Authors: Xiaoping Song, Hefang Sheng, Yueqiao Zhou, Yin Yu, Yingjiao He, Zihan Wang

Journal: Biotechnol Appl Biochem

PubMed ID: 34894362

Doi: 10.1002/bab.2298

Products & Services: Recombinant Antibody Expression

Edaravone Improves the Post-traumatic Brain Injury Dysfunction in Learning and Memory by Modulating Nrf2/ARE Signal Pathway

Authors: Xiushan Li, Jing Yu, Dongzhou Ma, Xuehui Weng

Journal: Clinics (Sao Paulo)

PubMed ID: 34878029

Doi: 10.6061/clinics/2021/e3131

Products & Services: Plasmid DNA Preparation

Biomaterial-mediated presentation of wnt5a mimetic ligands enhances chondrogenesis and metabolism of stem cells by activating non-canonical Wnt signaling

Authors: Yingrui Deng, Xiaoting Zhang, Rui Li, Zhuo Li, Boguang Yang, Peng Shi, Honglu Zhang, Chunming Wang, Chunyi Wen, Gang Li, Liming Bian

Journal: Biomaterials

PubMed ID: 34959028

Doi: 10.1016/j.biomaterials.2021.121316

Products & Services: Protein and Antibody Isolation

Tanshinone IIA sodium sulfonate attenuates inflammation by upregulating circ-Sirt1 and inhibiting the entry of NF-κB into the nucleus

Authors: Jiao Lan, Ke Li, Austin Gresham, Jifei Miao

Journal: Eur J Pharmacol

PubMed ID: 34896110

Doi: 10.1016/j.ejphar.2021.174693

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Deferasirox combination with eltrombopag shows anti-myelodysplastic syndrome effects by enhancing iron deprivation-related apoptosis

Authors: Lei Huang, Mengyue Tian, Zhaoyun Liu, Chunyan Liu, Rong Fu

Journal: J Investig Med

PubMed ID: 34921125

Doi: 10.1136/jim-2021-002147

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Seven-Month Analysis of Five SARS-CoV-2 Antibody Assay Results after ChAdOx1 nCoV-19 Vaccination: Significant Decrease in SARS-CoV-2 Antibody Titer

Authors: Seri Jeong, Nuri Lee, Su-Kyung Lee, Eun-Jung Cho, Jungwon Hyun, Min-Jeong Park, Wonkeun Song, Eun-Ju Jung, Heungjeong Woo, Yu-Bin Seo, Jin-Ju Park, Hyun-Soo Kim

Journal: Diagnostics (Basel)

PubMed ID: 35054251

Doi: 10.3390/diagnostics12010085

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Seven-Month Analysis of Five SARS-CoV-2 Antibody Assay Results after ChAdOx1 nCoV-19 Vaccination: Significant Decrease in SARS-CoV-2 Antibody Titer

Authors: Seri Jeong, Nuri Lee, Su-Kyung Lee, Eun-Jung Cho, Jungwon Hyun, Min-Jeong Park, Wonkeun Song, Eun-Ju Jung, Heungjeong Woo, Yu-Bin Seo, Jin-Ju Park, Hyun-Soo Kim

Journal: Diagnostics (Basel)

PubMed ID: 35054251

Doi: 10.3390/diagnostics12010085

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Developing a secretory AcGFP1-based IRES expression system for efficient production of mammalian recombinant proteins

Authors: Zhongcheng Zou, Matthew Spencer, Peter D Sun

Journal: Protein Expr Purif

PubMed ID: 34920134

Doi: 10.1016/j.pep.2021.106029

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COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer

Authors: Cong Zeng, John P Evans, Karthik Chakravarthy, Panke Qu, Sarah Reisinger, No-Joon Song, Mark P Rubinstein, Peter G Shields, Zihai Li, Shan-Lu Liu

Journal: Cancer Cell

PubMed ID: 34986328

Doi: 10.1016/j.ccell.2021.12.014

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The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling

Authors: Xihua Wang, Shuyuan Guan, Lingbin Sun, Zhongliang Dai

Journal: Environ Toxicol Pharmacol

PubMed ID: 34883242

Doi: 10.1016/j.etap.2021.103782

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Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

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Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

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Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

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Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

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CASP5 and CR1 as potential biomarkers for Kawasaki disease: an Integrated Bioinformatics-Experimental Study

Authors: Yazdan Rahmati, Hasan Mollanoori, Sajad Najafi, Sajjad Esmaeili, Mohammad Reza Alivand

Journal: BMC Pediatr

PubMed ID: 34895171

Doi: 10.1186/s12887-021-03003-5

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Key factors determining competitions between double-stranded RNAs in Tribolium castaneum

Authors: Xu Shen, Yingchuan Peng, Huifang Song, Jinda Wang, Jun Zhao, Peian Tang, Zhaojun Han, Kangxu Wang

Journal: Pestic Biochem Physiol

PubMed ID: 35082032

Doi: 10.1016/j.pestbp.2021.105009

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Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro

Authors: Lin Chen, Zhi-Qiang Pan, Chang-Bin Zhai

Journal: Folia Histochem Cytobiol

PubMed ID: 34905214

Doi: 10.5603/FHC.a2021.0031

Products & Services: Gene Fragments

Hydroxysafflor yellow A inhibits the proliferation, migration, and invasion of colorectal cancer cells through the PPARγ/PTEN/Akt signaling pathway

Authors: Dan Su, Chunye Lv

Journal: Bioengineered

PubMed ID: 34889713

Doi: 10.1080/21655979.2021.2009965

Products & Services: Gene Synthesis

An immunochromatographic assay utilizing magnetic nanoparticles to detect major peanut allergen Ara h 1 in processed foods

Authors: Hsin-Yi Yin, Yi-Ting Li, Wen-Che Tsai, Hong-Yu Dai, Hsiao-Wei Wen

Journal: Food Chem

PubMed ID: 34952385

Doi: 10.1016/j.foodchem.2021.131844

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Critical residues for proteolysis activity of maize chlorotic dwarf virus (MCDV) 3C-like protease and comparison of activity of orthologous waikavirus proteases

Authors: Lucy R Stewart, Matthew Willman, DeeMarie Marty, Anna Emmick Cole, Kristen Willie

Journal: Virology

PubMed ID: 34998226

Doi: 10.1016/j.virol.2021.12.008

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Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis

Authors: Yi-Ping Liu, Zhong-Zhi Qiu, Xu-Hui Li, En-You Li

Journal: World J Gastrointest Oncol

PubMed ID: 35070046

Doi: 10.4251/wjgo.v13.i12.2114

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Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma

Authors: Liya Wang, Lucia Unger, Hanan Sharif, Staffan Eriksson, Vinzenz Gerber, Henrik Rönnberg

Journal: BMC Mol Cell Biol

PubMed ID: 34906077

Doi: 10.1186/s12860-021-00399-x

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Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma

Authors: Liya Wang, Lucia Unger, Hanan Sharif, Staffan Eriksson, Vinzenz Gerber, Henrik Rönnberg

Journal: BMC Mol Cell Biol

PubMed ID: 34906077

Doi: 10.1186/s12860-021-00399-x

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KIAA1217 Promotes Epithelial-Mesenchymal Transition and Hepatocellular Carcinoma Metastasis by Interacting with and Activating STAT3

Authors: Yanhong Wang, Na Li, Yanping Zheng, Anqing Wang, Chunlei Yu, Zhenbo Song, Shuyue Wang, Ying Sun, Lihua Zheng, Guannan Wang, Lei Liu, Jingwen Yi, Yanxin Huang, Muqing Zhang, Yongli Bao, Luguo Sun

Journal: Int J Mol Sci

PubMed ID: 35008530

Doi: 10.3390/ijms23010104

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Exposure to in Asian Elephants () in Thailand

Authors: Ruenruetai Udonsom, Yoshifumi Nishikawa, Ragab M Fereig, Thitirat Topisit, Natchakorn Kulkaweewut, Supitcha Chanamrung, Charoonluk Jirapattharasate

Journal: Pathogens

PubMed ID: 35055950

Doi: 10.3390/pathogens11010002

Products & Services: Protein and Antibody Isolation

Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men

Authors: Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong

Journal: Emerg Microbes Infect

PubMed ID: 34709140

Doi: 10.1080/22221751.2021.1999777

Hsa_circ_0003204 Knockdown Weakens Ox-LDL-Induced Cell Injury by Regulating miR-188-3p/TRPC6 Axis in Human Carotid Artery Endothelial Cells and THP-1 Cells

Authors: Wenjia Peng, Shuai Li, Shiyue Chen, Jiacheng Yang, Ze Sun

Journal: Front Cardiovasc Med

PubMed ID: 34912856

Doi: 10.3389/fcvm.2021.731890

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Highly portable quantitative screening test for prostate-specific antigen at point of care

Authors: Balaji Srinivasan, David M Nanus, David Erickson, Saurabh Mehta

Journal: Curr Res Biotechnol

PubMed ID: 35083431

Doi: 10.1016/j.crbiot.2021.11.003

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Phytochrome interacting factor 3 regulates pollen mitotic division through auxin signalling and sugar metabolism pathways in tomato

Authors: Dandan Yang, Yue Liu, Muhammad Ali, Lei Ye, Changtian Pan, Mengzhuo Li, Xiaolin Zhao, Fangjie Yu, Xinai Zhao, Gang Lu

Journal: New Phytol

PubMed ID: 34812499

Doi: 10.1111/nph.17878

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Immunoglobulin a suppresses B cell receptor-mediated activation of mouse B cells with differential inhibition of signaling molecules

Authors: Kouya Yamaki, Masato Terashi, Saori Yamamoto, Rei Fujiwara, Jun-Ichi Inoue, Kishi Shimizu, Sakura Yanagita, Yuma Doi, Kei-Ichiro Kimura, Kayo Kotani, Mai Sugihara, Yutaka Koyama

Journal: Immunopharmacol Immunotoxicol

PubMed ID: 34844505

Doi: 10.1080/08923973.2021.2006216

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Robust Antibody Levels in Both Diabetic and Non-Diabetic Individuals After BNT162b2 mRNA COVID-19 Vaccination

Authors: Hamad Ali, Abdulmohsen Alterki, Sardar Sindhu, Barrak Alahmad, Maha Hammad, Salman Al-Sabah, Mohammad Alghounaim, Mohammad H Jamal, Ali Aldei, Mohammad J Mairza, Maitham Husain, Sriraman Deverajan, Rasheed Ahmad, Preethi Cherian, Irina Alkhairi, Abdullah Alkandari, Jehad Abubaker, Mohamed Abu-Farha, Fahd Al-Mulla

Journal: Front Immunol

PubMed ID: 34899701

Doi: 10.3389/fimmu.2021.752233

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Generation of a Novel High-Affinity Antibody Binding to PCSK9 Catalytic Domain with Slow Dissociation Rate by CDR-Grafting, Alanine Scanning and Saturated Site-Directed Mutagenesis for Favorably Treating Hypercholesterolemia

Authors: Zhengli Bai, Menglong Xu, Ying Mei, Tuo Hu, Panpan Zhang, Manman Chen, Wenxiu Lv, Chenchen Lu, Shuhua Tan

Journal: Biomedicines

PubMed ID: 34944600

Doi: 10.3390/biomedicines9121783

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Methodology to Quantify Collagen Subtypes and Crosslinks: Application in Minipig Cartilages

Authors: Benjamin J Bielajew, Jerry C Hu, Kyriacos A Athanasiou

Journal: Cartilage

PubMed ID: 34823380

Doi: 10.1177/19476035211060508

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Delayed fractional dosing with RTS,S/AS01 improves humoral immunity to malaria via a balance of polyfunctional NANP6- and Pf16-specific antibodies

Authors: Jishnu Das, Jonathan K Fallon, Timothy C Yu, Ashlin Michell, Todd J Suscovich, Caitlyn Linde, Harini Natarajan, Joshua Weiner, Margherita Coccia, Scott Gregory, Margaret E Ackerman, Elke Bergmann-Leitner, Laura Fontana, Sheetij Dutta, Douglas A Lauffenburger, Erik Jongert, Ulrike Wille-Reece, Galit Alter

Journal: Med (N Y)

PubMed ID: 35590199

Doi: 10.1016/j.medj.2021.10.003

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Eurasian Avian-like M1 Plays More Important Role than M2 in Pathogenicity of 2009 Pandemic H1N1 Influenza Virus in Mice

Authors: Lixiang Xie, Guanlong Xu, Lingxiang Xin, Zhaofei Wang, Rujuan Wu, Mingqing Wu, Yuqiang Cheng, Hengan Wang, Yaxian Yan, Jingjiao Ma, Jianhe Sun

Journal: Viruses

PubMed ID: 34960604

Doi: 10.3390/v13122335

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Bioinspired gelatin/bioceramic composites loaded with bone morphogenetic protein-2 (BMP-2) promote osteoporotic bone repair

Authors: M C Echave, I Erezuma, N Golafshan, M Castilho, F B Kadumudi, C Pimenta-Lopes, F Ventura, A Pujol, J J Jimenez, J A Camara, R Hernáez-Moya, L Iturriaga, L Sáenz Del Burgo, I Iloro, M Azkargorta, F Elortza, R Lakshminarayanan, T H Al-Tel, P García-García, R Reyes, A Delgado, C Évora, J L Pedraz, A Dolatshahi-Pirouz, G Orive

Journal: Biomater Adv

PubMed ID: 35513949

Doi: 10.1016/j.msec.2021.112539

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Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use

Authors: Chunyu Wang, Jiaxu Hong, Zhenlin Yang, Xujiao Zhou, Yuhan Yang, Yu Kong, Binfan Chen, Huifang Wu, Bin-Zhi Qian, Dimiter S Dimitrov, Xingtao Zhou, Yanling Wu, Tianlei Ying

Journal: Small Methods

PubMed ID: 35174992

Doi: 10.1002/smtd.202100966

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Immuno-transcriptomic profiling of extracranial pediatric solid malignancies

Authors: Andrew S Brohl, Sivasish Sindiri, Jun S Wei, David Milewski, Hsien-Chao Chou, Young K Song, Xinyu Wen, Jeetendra Kumar, Hue V Reardon, Uma S Mudunuri, Jack R Collins, Sushma Nagaraj, Vineela Gangalapudi, Manoj Tyagi, Yuelin J Zhu, Katherine E Masih, Marielle E Yohe, Jack F Shern, Yue Qi, Udayan Guha, Daniel Catchpoole, Rimas J Orentas, Igor B Kuznetsov, Nicolas J Llosa, John A Ligon, Brian K Turpin, Daniel G Leino, Shintaro Iwata, Irene L Andrulis, Jay S Wunder, Silvia R C Toledo, Paul S Meltzer, Ching Lau, Beverly A Teicher, Heather Magnan, Marc Ladanyi, Javed Khan

Journal: Cell Rep

PubMed ID: 34818552

Doi: 10.1016/j.celrep.2021.110047

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ACE Inhibitory Peptide from Skin Collagen Hydrolysate of as Potential for Protecting HUVECs Injury

Authors: Shuilin Cai, Nan Pan, Min Xu, Yongchang Su, Kun Qiao, Bei Chen, Bingde Zheng, Meitian Xiao, Zhiyu Liu

Journal: Mar Drugs

PubMed ID: 34940654

Doi: 10.3390/md19120655

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Kinetic proofreading of lipochitooligosaccharides determines signal activation of symbiotic plant receptors

Authors: Kira Gysel, Mette Laursen, Mikkel B Thygesen, Damiano Lironi, Zoltán Bozsóki, Christian T Hjuler, Nicolai N Maolanon, Jeryl Cheng, Peter K Bjørk, Maria Vinther, Lene H Madsen, Henriette Rübsam, Artur Muszyński, Arshia Ghodrati, Parastoo Azadi, John T Sullivan, Clive W Ronson, Knud J Jensen, Mickaël Blaise, Simona Radutoiu, Jens Stougaard, Kasper R Andersen

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34716271

Doi: 10.1073/pnas.2111031118

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A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants

Authors: Novalia Pishesha, Thibault J Harmand, Paul W Rothlauf, Patrique Praest, Ryan K Alexander, Renate van den Doel, Mariel J Liebeskind, Maria A Vakaki, Nicholas McCaul, Charlotte Wijne, Elisha Verhaar, William Pinney, Hailey Heston, Louis-Marie Bloyet, Marjorie Cornejo Pontelli, Ma Xenia G Ilagan, Robert Jan Lebbink, William J Buchser, Emmanuel J H J Wiertz, Sean P J Whelan, Hidde L Ploegh

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34654739

Doi: 10.1073/pnas.2116147118

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First cases of SARS-CoV-2 infection in dogs and cats in Thailand

Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Napawan Bunpapong, Supanat Boonyapisitsopa, Rachod Tantilertcharoen, Navapon Techakriengkrai, Sirilak Surachetpong, Ratanaporn Tangwangvivat, Kamol Suwannakarn, Alongkorn Amonsin

Journal: Transbound Emerg Dis

PubMed ID: 34739748

Doi: 10.1111/tbed.14383

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

Authors: Yaozong Chen, Lulu Sun, Irfan Ullah, Guillaume Beaudoin-Bussières, Sai Priya Anand, Andrew P Hederman, William D Tolbert, Rebekah Sherburn, Dung N Nguyen, Lorie Marchitto, Shilei Ding, Di Wu, Yuhong Luo, Suneetha Gottumukkala, Sean Moran, Priti Kumar, Grzegorz Piszczek, Walther Mothes, Margaret E Ackerman, Andrés Finzi, Pradeep D Uchil, Frank J Gonzalez, Marzena Pazgier

Journal: biorxiv

PubMed ID: 34845451

Doi: 10.1101/2021.11.24.469776

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AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway

Authors: Hoi Yin Mak, Qian Ouyang, Sergey Tumanov, Jiesi Xu, Ping Rong, Feitong Dong, Sin Man Lam, Xiaowei Wang, Ivan Lukmantara, Ximing Du, Mingming Gao, Andrew J Brown, Xin Gong, Guanghou Shui, Roland Stocker, Xun Huang, Shuai Chen, Hongyuan Yang

Journal: Nat Commun

PubMed ID: 34824276

Doi: 10.1038/s41467-021-27279-4

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Regulation of neuronal excitation-transcription coupling by Kv21-induced clustering of somatic L-type Ca channels at ER-PM junctions

Authors: Nicholas C Vierra, Samantha C O'Dwyer, Collin Matsumoto, L Fernando Santana, James S Trimmer

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34750263

Doi: 10.1073/pnas.2110094118

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Polymerization of C9 enhances bacterial cell envelope damage and killing by membrane attack complex pores

Authors: Dennis J Doorduijn, Dani A C Heesterbeek, Maartje Ruyken, Carla J C de Haas, Daphne A C Stapels, Piet C Aerts, Suzan H M Rooijakkers, Bart W Bardoel

Journal: PLoS Pathog

PubMed ID: 34752492

Doi: 10.1371/journal.ppat.1010051

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Immune signatures underlying post-acute COVID-19 lung sequelae

Authors: I S Cheon, C Li, Y M Son, N P Goplen, Y Wu, T Cassmann, Z Wang, X Wei, J Tang, Y Li, H Marlow, S Hughes, L Hammel, T M Cox, E Goddery, K Ayasoufi, D Weiskopf, J Boonyaratanakornkit, H Dong, H Li, R Chakraborty, A J Johnson, E Edell, J J Taylor, M H Kaplan, A Sette, B J Bartholmai, R Kern, R Vassallo, J Sun

Journal: Sci Immunol

PubMed ID: 34591653

Doi: 10.1126/sciimmunol.abk1741

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Pharmacokinetics of Monoclonal Antibody and Antibody Fragments in the Mouse Eye Following Systemic Administration

Authors: David Bussing, Zhe Li, Yingyi Li, Hsuan-Ping Chang, Hsueh-Yuan Chang, Leiming Guo, Ashwni Verma, Dhaval K Shah

Journal: AAPS J

PubMed ID: 34750690

Doi: 10.1208/s12248-021-00647-0

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Robust Antigen-Specific T Cell Activation within Injectable 3D Synthetic Nanovaccine Depots

Authors: Jorieke Weiden, Marjolein Schluck, Melina Ioannidis, Eric A W van Dinther, Mahboobeh Rezaeeyazdi, Fawad Omar, Juulke Steuten, Dion Voerman, Jurjen Tel, Mustafa Diken, Sidi A Bencherif, Carl G Figdor, Martijn Verdoes

Journal: ACS Biomater Sci Eng

PubMed ID: 34734689

Doi: 10.1021/acsbiomaterials.0c01648

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Proteogenomic discovery of neoantigens facilitates personalized multi-antigen targeted T cell immunotherapy for brain tumors

Authors: Samuel Rivero-Hinojosa, Melanie Grant, Aswini Panigrahi, Huizhen Zhang, Veronika Caisova, Catherine M Bollard, Brian R Rood

Journal: Nat Commun

PubMed ID: 34795224

Doi: 10.1038/s41467-021-26936-y

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Humoral immune response following prime and boost BNT162b2 vaccination in people living with HIV on antiretroviral therapy

Authors: Nils Jedicke, Metodi V Stankov, Anne Cossmann, Alexandra Dopfer-Jablonka, Christine Knuth, Gerrit Ahrenstorf, Gema Morillas Ramos, Georg M N Behrens

Journal: HIV Med

PubMed ID: 34725907

Doi: 10.1111/hiv.13202

Co-translational biogenesis of lipid droplet integral membrane proteins

Authors: Pawel Leznicki, Hayden O Schneider, Jada V Harvey, Wei Q Shi, Stephen High

Journal: J Cell Sci

PubMed ID: 34558621

Doi: 10.1242/jcs.259220

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Quench-Release-Based Fluorescent Immunosensor for the Rapid Detection of Tumor Necrosis Factor α

Authors: Haimei Li, Xinyu Li, Limei Chen, Baowei Li, Hang Dong, Hongying Liu, Xueying Yang, Hiroshi Ueda, Jinhua Dong

Journal: ACS Omega

PubMed ID: 34841143

Doi: 10.1021/acsomega.1c03941

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The ZO-1 protein Polychaetoid as an upstream regulator of the Hippo pathway in Drosophila

Authors: Qingliang Sang, Gang Wang, David B Morton, Hui Wu, Baotong Xie

Journal: PLoS Genet

PubMed ID: 34748546

Doi: 10.1371/journal.pgen.1009894

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Zipper head mechanism of telomere synthesis by human telomerase

Authors: Futang Wan, Yongbo Ding, Yuebin Zhang, Zhenfang Wu, Shaobai Li, Lin Yang, Xiangyu Yan, Pengfei Lan, Guohui Li, Jian Wu, Ming Lei

Journal: Cell Res

PubMed ID: 34782750

Doi: 10.1038/s41422-021-00586-7

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Hybridization-proximity labeling reveals spatially ordered interactions of nuclear RNA compartments

Authors: Karen Yap, Tek Hong Chung, Eugene V Makeyev

Journal: Mol Cell

PubMed ID: 34741808

Doi: 10.1016/j.molcel.2021.10.009

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Increased carvone production in Escherichia coli by balancing limonene conversion enzyme expression via targeted quantification concatamer proteome analysis

Authors: Erika Yoshida, Motoki Kojima, Munenori Suzuki, Fumio Matsuda, Kazutaka Shimbo, Akiko Onuki, Yousuke Nishio, Yoshihiro Usuda, Akihiko Kondo, Jun Ishii

Journal: Sci Rep

PubMed ID: 34764337

Doi: 10.1038/s41598-021-01469-y

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Inhibition of miR-15a-5p Promotes the Chemoresistance to Pirarubicin in Hepatocellular Carcinoma via Targeting eIF4E

Authors: Ying Zhang, Qingsong Tie, Zhiwei Bao, Zhi Shao, Lan Zhang

Journal: Comput Math Methods Med

PubMed ID: 34812269

Doi: 10.1155/2021/6468405

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Characterization of a novel transcript variant: implications for D6D activity regulation in cells

Authors: Kristin A Marks, Maria F Fernandes, Kalsha H Diaguarachchige De Silva, Michelle V Tomczewski, Ken D Stark, Robin E Duncan

Journal: Biochem Cell Biol

PubMed ID: 34738827

Doi: 10.1139/bcb-2020-0538

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A novel framework integrating AI model and enzymological experiments promotes identification of SARS-CoV-2 3CL protease inhibitors and activity-based probe

Authors: Fan Hu, Lei Wang, Yishen Hu, Dongqi Wang, Weijie Wang, Jianbing Jiang, Nan Li, Peng Yin

Journal: Brief Bioinform

PubMed ID: 34368837

Doi: 10.1093/bib/bbab301

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Clinical Considerations During Breakthrough Coronavirus Disease 2019 Infections in Vaccinated Individuals With Autoimmunity

Authors: Joseph M Rocco, Luxin Pei, Frances Galindo, Elizabeth Laidlaw, Irini Sereti

Journal: Open Forum Infect Dis

PubMed ID: 34917696

Doi: 10.1093/ofid/ofab577

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High-throughput Microwell-seq 2.0 profiles massively multiplexed chemical perturbation

Authors: Haide Chen, Yuan Liao, Guodong Zhang , Zhongyi Sun, Lei Yang, Xing Fang, Huiyu Sun, Lifeng Ma, Yuting Fu, Jingyu Li, Qile Guo, Xiaoping Han, Guoji Guo

Journal: Cell Discov

PubMed ID: 34750394

Doi: 10.1038/s41421-021-00333-7

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Development of a novel promoter engineering-based strategy for creating an efficient para-nitrophenol-mineralizing bacterium

Authors: Kaiyue Huo, Yujie Liu, Rui Huang, Yiting Zhang, Honglu Liu, You Che, Chao Yang

Journal: J Hazard Mater.

PubMed ID: 34753648

Doi: 10.1016/j.jhazmat.2021.127672.

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Neutralization of SARS-CoV-2 Variants in Transplant Recipients After Two and Three Doses of mRNA-1273 Vaccine : Secondary Analysis of a Randomized Trial

Authors: Deepali Kumar, Victor H Ferreira, Victoria G Hall, Queenie Hu, Reuben Samson, Terrance Ku, Matthew Ierullo, Beata Majchrzak-Kita, George Tomlinson, Anne-Claude Gingras, Atul Humar

Journal: Ann Intern Med

PubMed ID: 34807716

Doi: 10.7326/M21-3480

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Author Correction: Disulfide-compatible phage-assisted continuous evolution in the periplasmic space

Authors: Mary S Morrison, Tina Wang, Aditya Raguram, Colin Hemez, David R Liu

Journal: Nat Commun

PubMed ID: 34789771

Doi: 10.1038/s41467-021-27102-0

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