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Polydopamine nanoparticles with different sizes for NIR-promoted gene delivery and synergistic photothermal therapy

Authors: Peng Zhang, Xinfang Li, Qinan Xu, Youxiang Wang, Jian Ji

Journal: Colloids Surf B Biointerfaces

PubMed ID: 34601352

Doi: 10.1016/j.colsurfb.2021.112125

Products & Services: Molecular Biology Reagents

Ceramide Regulates Anti-Tumor Mechanisms of Erianin in Androgen-Sensitive and Castration-Resistant Prostate Cancers

Authors: I Gusti Md Gde Surya C Trapika, Xin Tracy Liu, Long Hoa Chung, Felcia Lai, Chanlu Xie, Yang Zhao, Shaohui Cui, Jinbiao Chen, Collin Tran, Qian Wang, Shubiao Zhang, Anthony S Don, George Qian Li, Jane R Hanrahan, Yanfei Qi

Journal: Front Oncol

PubMed ID: 34604081

Doi: 10.3389/fonc.2021.738078

Products & Services: Molecular Biology Reagents

Impaired Antibody-Dependent Cellular Cytotoxicity in a Spanish Cohort of Patients With COVID-19 Admitted to the ICU

Authors: Lorena Vigón, Javier García-Pérez, Sara Rodríguez-Mora, Montserrat Torres, Elena Mateos, María Castillo de la Osa, Miguel Cervero, Rosa Malo De Molina, Cristina Navarro, María Aránzazu Murciano-Antón, Valentín García-Gutiérrez, Vicente Planelles, José Alcamí, Mayte Pérez-Olmeda, Mayte Coiras, María Rosa López-Huertas

Journal: Front Immunol

PubMed ID: 34616404

Doi: 10.3389/fimmu.2021.742631

Products & Services: Mammalian Expression

Bitter Taste Receptor T2R14 Modulates Gram-Positive Bacterial Internalization and Survival in Gingival Epithelial Cells

Authors: Manoj Reddy Medapati, Anjali Yadav Bhagirath, Nisha Singh, Robert J Schroth, Rajinder P Bhullar, Kangmin Duan, Prashen Chelikani

Journal: Int J Mol Sci

PubMed ID: 34576085

Doi: 10.3390/ijms22189920

Products & Services: Mammalian Expression

The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling

Authors: Chen Shen, Anmada Nayak, Leif R Neitzel, Amber A Adams, Maya Silver-Isenstadt, Leah M Sawyer, Hassina Benchabane, Huilan Wang, Nawat Bunnag, Bin Li, Daniel T Wynn, Fan Yang, Marta Garcia-Contreras, Charles H Williams, Sivanesan Dakshanamurthy, Charles C Hong, Nagi G Ayad, Anthony J Capobianco, Yashi Ahmed, Ethan Lee, David J Robbins

Journal: Nat Commun

PubMed ID: 34489457

Doi: 10.1038/s41467-021-25634-z

Products & Services: Mammalian Expression

ONAC066, A Stress-Responsive NAC Transcription Activator, Positively Contributes to Rice Immunity Against Through Modulating Expression of and Three Cytochrome P450 Genes

Authors: Xi Yuan, Hui Wang, Yan Bi, Yuqing Yan, Yizhou Gao, Xiaohui Xiong, Jiajing Wang, Dayong Li, Fengming Song

Journal: Front Plant Sci

PubMed ID: 34567053

Doi: 10.3389/fpls.2021.749186

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Trivalent Subunit Vaccine Candidates for COVID-19 and Their Delivery Devices

Authors: Oscar A Ortega-Rivera, Matthew D Shin, Angela Chen, Veronique Beiss, Miguel A Moreno-Gonzalez, Miguel A Lopez-Ramirez, Maria Reynoso, Hong Wang, Brett L Hurst, Joseph Wang, Jonathan K Pokorski, Nicole F Steinmetz

Journal: J Am Chem Soc

PubMed ID: 34490778

Doi: 10.1021/jacs.1c06600

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Rapid reconstruction of porcine reproductive and respiratory syndrome virus using synthetic DNA fragments

Authors: Julien Mélade, Géraldine Piorkowski, Hawa Sophia Bouzidi, Alain Medawar, Claudine Raffy, Xavier de Lamballerie, Antoine Nougairède

Journal: Comput Struct Biotechnol J

PubMed ID: 34589186

Doi: 10.1016/j.csbj.2021.08.040

Products & Services: GenParts™ DNA Fragments

Shaping Liposomes by Cell-Free Expressed Bacterial Microtubules

Authors: Johannes Kattan, Anne Doerr, Marileen Dogterom, Christophe Danelon

Journal: ACS Synth Biol

PubMed ID: 34585918

Doi: 10.1021/acssynbio.1c00278

Products & Services: GenParts™ DNA Fragments

EndoBind detects endogenous protein-protein interactions in real time

Authors: Anke Bill, Sheryll Espinola, Daniel Guthy, Jacob R Haling, Mylene Lanter, Min Lu, Anthony Marelli, Angelica Mendiola, Loren Miraglia, Brandon L Taylor, Leonardo Vargas, Anthony P Orth, Frederick J King

Journal: Commun Biol

PubMed ID: 34526658

Doi: 10.1038/s42003-021-02600-5

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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M inhibitors

Authors: Srinivas Chamakuri, Shuo Lu, Melek Nihan Ucisik, Kurt M Bohren, Ying-Chu Chen, Huang-Chi Du, John C Faver, Ravikumar Jimmidi, Feng Li, Jian-Yuan Li, Pranavanand Nyshadham, Stephen S Palmer, Jeroen Pollet, Xuan Qin, Shannon E Ronca, Banumathi Sankaran, Kiran L Sharma, Zhi Tan, Leroy Versteeg, Zhifeng Yu, Martin M Matzuk, Timothy Palzkill, Damian W Young

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34426525

Doi: 10.1073/pnas.2111172118

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Loading Effect of Chitosan Derivative Nanoparticles on Different Antigens and Their Immunomodulatory Activity on Dendritic Cells

Authors: Chaojie Xu, Ronge Xing, Song Liu, Yukun Qin, Kecheng Li, Huahua Yu, Pengcheng Li

Journal: Mar Drugs

PubMed ID: 34677435

Doi: 10.3390/md19100536

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Stable isotope tracing to assess tumor metabolism in vivo

Authors: Brandon Faubert, Alpaslan Tasdogan, Sean J Morrison, Thomas P Mathews, Ralph J DeBerardinis

Journal: Nat Protoc

PubMed ID: 34535790

Doi: 10.1038/s41596-021-00605-2

Products & Services: Endotoxin Detection & Removal System

Genomic investigation of a household SARS-CoV-2 disease cluster in Arizona involving a cat, dog, and pet owner

Authors: Hayley D Yaglom, Gavriella Hecht, Andrew Goedderz, Daniel Jasso-Selles, Jennifer L Ely, Irene Ruberto, Jolene R Bowers, David M Engelthaler, Heather Venkat

Journal: One Health

PubMed ID: 34604494

Doi: 10.1016/j.onehlt.2021.100333

Products & Services: Protein Reagents and Products

FGF21 ameliorates hepatic fibrosis by multiple mechanisms

Authors: Fanrui Meng, Mir Hassan Khoso, Kai Kang, Qi He, Yukai Cao, Xinghao Jiang, Wei Xiao, Deshan Li

Journal: Mol Biol Rep

PubMed ID: 34536190

Doi: 10.1007/s11033-021-06707-0

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular and Enzymatic Characterization of Flavonoid 3'-Hydroxylase of ×

Authors: Julia Weissensteiner, Christian Molitor, Silvija Marinovic, Lisa Führer, Syed Waqas Hassan, Olly Sanny Hutabarat, Andreas Spornberger, Karl Stich, Johanna Hausjell, Oliver Spadiut, Christian Haselmair-Gosch, Heidi Halbwirth

Journal: Plants (Basel)

PubMed ID: 34579488

Doi: 10.3390/plants10091956

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Hinge influences in murine IgG binding to Cryptococcus neoformans capsule

Authors: Diane Sthefany Lima de Oliveira, Verenice Paredes, Adrielle Veloso Caixeta, Nicole Moreira Henriques, Maggie P Wear, Patrícia Albuquerque, Maria Sueli Soares Felipe, Arturo Casadevall, André Moraes Nicola

Journal: Immunology

PubMed ID: 34458991

Doi: 10.1111/imm.13411

Products & Services: Recombinant Antibody Expression

Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Ovalbumin-Specific Cell Mediated Immunity in Mice Model

Authors: So Yeon Ahn, Chau Thuy Tien Le, Eun-Ju Ko

Journal: Biology (Basel)

PubMed ID: 34571785

Doi: 10.3390/biology10090908

Products & Services: Recombinant Proteins

Marburg and Ebola Virus mRNA 3' Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing

Authors: Sudip Khadka, Caroline G Williams, Joyce Sweeney-Gibbons, Christopher F Basler

Journal: J Virol

PubMed ID: 34346762

Doi: 10.1128/JVI.00652-21

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Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients

Authors: Yuanling Yu, Meiyu Wang, Xiaoai Zhang, Shufen Li, Qingbin Lu, Haolong Zeng, Hongyan Hou, Hao Li, Mengyi Zhang, Fei Jiang, Jiajing Wu, Ruxia Ding, Zehua Zhou, Min Liu, Weixue Si, Tao Zhu, Hangwen Li, Jie Ma, Yuanyuan Gu, Guangbiao She, Xiaokun Li, Yulan Zhang, Ke Peng, Weijin Huang, Wei Liu, Youchun Wang

Journal: Signal Transduct Target Ther

PubMed ID: 34561414

Doi: 10.1038/s41392-021-00759-1

Products & Services: Mammalian Expression

Tissue-Resident-Memory CD8 T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes

Authors: Tao Peng, Khamsone Phasouk, Catherine N Sodroski, Sijie Sun, Yon Hwangbo, Erik D Layton, Lei Jin, Alexis Klock, Kurt Diem, Amalia S Magaret, Lichen Jing, Kerry Laing, Alvason Li, Meei-Li Huang, Max Mertens, Christine Johnston, Keith R Jerome, David M Koelle, Anna Wald, David M Knipe, Lawrence Corey, Jia Zhu

Journal: Front Immunol

PubMed ID: 34552595

Doi: 10.3389/fimmu.2021.735643

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Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin

Authors: Delia Susan-Resiga, Emmanuelle Girard, Rachid Essalmani, Anna Roubtsova, Jadwiga Marcinkiewicz, Rabeb M Derbali, Alexandra Evagelidis, Jae H Byun, Paul F Lebeau, Richard C Austin, Nabil G Seidah

Journal: J Biol Chem

PubMed ID: 34508778

Doi: 10.1016/j.jbc.2021.101177

Products & Services: Mammalian Expression

Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton

Authors: Katharina Vestre, Irene Persiconi, Marita Borg Distefano, Nadia Mensali, Noemi Antonella Guadagno, Marine Bretou, Sébastien Wälchli, Catharina Arnold-Schrauf, Oddmund Bakke, Marc Dalod, Ana-Maria Lennon-Dumenil, Cinzia Progida

Journal: J Cell Sci

PubMed ID: 34494097

Doi: 10.1242/jcs.259221

Products & Services: Proteins, Expression, Isolation and Analysis

Expression of Biofilm-Degrading Enzymes in Plants and Automated High-Throughput Activity Screening Using Experimental Biofilms

Authors: P Opdensteinen, S J Dietz, B B Gengenbach, J F Buyel

Journal: Front Bioeng Biotechnol

PubMed ID: 34621728

Doi: 10.3389/fbioe.2021.708150

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Lipopolysaccharide Is a 4-Aminoarabinose Donor to Exogenous Polyisoprenyl Phosphates through the Reverse Reaction of the Enzyme ArnT

Authors: Beth A Scarbrough, Colleen R Eade, Amanda J Reid, Tiffany C Williams, Jerry M Troutman

Journal: ACS Omega

PubMed ID: 34632229

Doi: 10.1021/acsomega.1c04036

Products & Services: Proteins, Expression, Isolation and Analysis

Novel Antimicrobial Peptides from a Cecropin-Like Region of Heteroscorpine-1 from Venom with Membrane Disruption Activity

Authors: Rima Erviana, Yutthakan Saengkun, Prapenpuksiri Rungsa, Nisachon Jangpromma, Patcharaporn Tippayawat, Sompong Klaynongsruang, Jureerut Daduang, Sakda Daduang

Journal: Molecules

PubMed ID: 34641415

Doi: 10.3390/molecules26195872

Products & Services: Peptide Synthesis

Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions

Authors: Md Sifatul Islam, Md Soyib Hasan, Md Nazmul Hasan, Shamsul H Prodhan, Tahmina Islam, Ajit Ghosh

Journal: Sci Rep

PubMed ID: 34521910

Doi: 10.1038/s41598-021-97691-9

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Resistance of SARS-CoV-2 Delta variant to neutralization by BNT162b2-elicited antibodies in Asians

Authors: Bei Wang, Yun Shan Goh, Siew-Wai Fong, Barnaby Edward Young, Eve Zi Xian Ngoh, Jean-Marc Chavatte, Siti Nazihah Mohd Salleh, Nicholas Kim-Wah Yeo, Siti Naqiah Amrun, Pei Xiang Hor, Chiew Yee Loh, Chia Yin Lee, Yi-Hao Chan, Zi Wei Chang, Matthew Zirui Tay, Angeline Rouers, Anthony Torres-Ruesta, Guillaume Carissimo, Mun Kuen Soh, Raphael Tze Chuen Lee, Yani Xu, Surinder Pada, Raymond Tzer Pin Lin, Yee-Sin Leo, David C Lye, Sebastian Maurer-Stroh, Lisa F P Ng, Laurent Renia, Cheng-I Wang

Journal: Lancet Reg Health West Pac

PubMed ID: 34568853

Doi: 10.1016/j.lanwpc.2021.100276

Products & Services: Recombinant Proteins

MicroRNA-140-5p represses chondrocyte pyroptosis and relieves cartilage injury in osteoarthritis by inhibiting cathepsin B/Nod-like receptor protein 3

Authors: Lei Zhang, Jianjun Qiu, Jixiang Shi, Shaoyang Liu, Hanlin Zou

Journal: Bioengineered

PubMed ID: 34565303

Doi: 10.1080/21655979.2021.1985342

Products & Services: Gene Synthesis

Ultrafast, sensitive, and portable detection of COVID-19 IgG using flexible organic electrochemical transistors

Authors: Hong Liu, Anneng Yang, Jiajun Song, Naixiang Wang, Puiyiu Lam, Yuenling Li, Helen Ka-Wai Law, Feng Yan

Journal: Sci Adv

PubMed ID: 34524851

Doi: 10.1126/sciadv.abg8387

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Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys

Authors: Julien Baruteau, Sharon C Cunningham, Berna Seker Yilmaz, Dany P Perocheau, Simon Eaglestone, Derek Burke, Adrian J Thrasher, Simon N Waddington, Leszek Lisowski, Ian E Alexander, Paul Gissen

Journal: Mol Ther Methods Clin Dev

PubMed ID: 34703837

Doi: 10.1016/j.omtm.2021.09.005

Products & Services: Codon Optimization

An observational study of breakthrough SARS-CoV-2 Delta variant infections among vaccinated healthcare workers in Vietnam

Authors: Nguyen Van Vinh Chau, Nghiem My Ngoc, Lam Anh Nguyet, Vo Minh Quang, Nguyen Thi Han Ny, Dao Bach Khoa, Nguyen Thanh Phong, Le Mau Toan, Nguyen Thi Thu Hong, Nguyen Thi Kim Tuyen, Voong Vinh Phat, Le Nguyen Truc Nhu, Nguyen Huynh Thanh Truc, Bui Thi Ton That, Huynh Phuong Thao, Tran Nguyen Phuong Thao, Vo Trong Vuong, Tran Thi Thanh Tam, Ngo Tan Tai, Ho The Bao, Huynh Thi Kim Nhung, Nguyen Thi Ngoc Minh, Nguyen Thi My Tien, Nguy Cam Huy, Marc Choisy, Dinh Nguyen Huy Man, Dinh Thi Bich Ty, Nguyen To Anh, Le Thi Tam Uyen, Tran Nguyen Hoang Tu, Lam Minh Yen, Nguyen Thanh Dung, Le Manh Hung, Nguyen Thanh Truong, Tran Tan Thanh, Guy Thwaites, Le Van Tan

Journal: EClinicalMedicine

PubMed ID: 34608454

Doi: 10.1016/j.eclinm.2021.101143

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Loss of Function of and in Rice Promotes Early Maturing and Semi-Dwarfism in γ-Irradiated IWP and Genome-Edited Pusa Basmati-1

Authors: M T Andrew-Peter-Leon, Ramchander Selvaraj, K K Kumar, Mehanathan Muthamilarasan, Jeshima Khan Yasin, M Arumugam Pillai

Journal: Front Plant Sci

PubMed ID: 34630462

Doi: 10.3389/fpls.2021.714066

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Plant-Expressed Receptor Binding Domain of the SARS-CoV-2 Spike Protein Elicits Humoral Immunity in Mice

Authors: Puna Maya Maharjan, Jinyeong Cheon, Jiyun Jung, Haerim Kim, Jaewon Lee, Minjeong Song, Gi Uk Jeong, Youngchan Kwon, Byoungshik Shim, Sunghwa Choe

Journal: Vaccines (Basel)

PubMed ID: 34579215

Doi: 10.3390/vaccines9090978

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Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted

Authors: Jeremy D Rubinstein, Xiang Zhu, Thomas Leemhuis, Giang Pham, Lorraine Ray, Sana Emberesh, Sonata Jodele, Shawn Thomas, Jose A Cancelas, Catherine M Bollard, Patrick J Hanley, Michael D Keller, Olivia Grimley, Diana Clark, Teri Clark, Cecilia S Lindestam Arlehamn, Alessandro Sette, Stella M Davies, Adam S Nelson, Michael S Grimley, Carolyn Lutzko

Journal: Blood Adv

PubMed ID: 34473237

Doi: 10.1182/bloodadvances.2021004456

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Glycosylation reduces the glycan-independent immunomodulatory effect of recombinant Orysata lectin in Drosophila S2 cells

Authors: Pengyu Chen, Kristof De Schutter, Sonia Serna, Simin Chen, Qun Yang, Niels-Christian Reichardt, Els J M Van Damme, Guy Smagghe

Journal: Sci Rep

PubMed ID: 34504130

Doi: 10.1038/s41598-021-97161-2

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Circular RNA hsa_circ_0001598 promotes programmed death-ligand-1-mediated immune escape and trastuzumab resistance via sponging miR-1184 in breast cancer cells

Authors: Li Huang, Jing Ma, Min Cui

Journal: Immunol Res

PubMed ID: 34559381

Doi: 10.1007/s12026-021-09237-w

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A Peptide-Based Assay Discriminates Individual Antibody Response to the COVID-19 Pfizer/BioNTech mRNA Vaccine

Authors: Immacolata Polvere, Serena Voccola, Alfredina Parrella, Gaetano Cardinale, Lucrezia Zerillo, Romualdo Varricchio, Jessica Raffaella Madera, Romania Stilo, Pasquale Vito, Tiziana Zotti

Journal: Vaccines (Basel)

PubMed ID: 34579224

Doi: 10.3390/vaccines9090987

Prior infection and age impacts antibody persistence after SARS-CoV-2 mRNA vaccine

Authors: Elizabeth Fraley, Cas LeMaster, Santosh Khanal, Dithi Banerjee, Tomi Pastinen, Elin Grundberg, Rangaraj Selvarangan, Todd Bradley

Journal: Clin Infect Dis

PubMed ID: 34551091

Doi: 10.1093/cid/ciab850

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Prior infection and age impacts antibody persistence after SARS-CoV-2 mRNA vaccine

Authors: Elizabeth Fraley, Cas LeMaster, Santosh Khanal, Dithi Banerjee, Tomi Pastinen, Elin Grundberg, Rangaraj Selvarangan, Todd Bradley

Journal: Clin Infect Dis

PubMed ID: 34551091

Doi: 10.1093/cid/ciab850

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Cytochrome P450-catalyzed biosynthesis of furanoditerpenoids in the bioenergy crop switchgrass (Panicum virgatum L)

Authors: Andrew Muchlinski, Meirong Jia, Kira Tiedge, Jason S Fell, Kyle A Pelot, Lisl Chew, Danielle Davisson, Yuxuan Chen, Justin Siegel, John T Lovell, Philipp Zerbe

Journal: Plant J

PubMed ID: 34514645

Doi: 10.1111/tpj.15492

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Recombinant expression, purification, and characterization of full-length human BST-2 from Escherichia coli

Authors: Amukelani Marivate, Zikhona Njengele-Tetyana, Muhammad Qasim Fish, Salerwe Mosebi

Journal: Protein Expr Purif

PubMed ID: 34500069

Doi: 10.1016/j.pep.2021.105969

Products & Services: Recombinant Proteins

Multiplexed analysis of small extracellular vesicle-derived mRNAs by droplet digital PCR and machine learning improves breast cancer diagnosis

Authors: Chunchen Liu, Bo Li, Huixian Lin, Chao Yang, Jingyun Guo, Binbin Cui, Weilun Pan, Junjie Feng, Tingting Luo, Fuxin Chu, Xiaonan Xu, Lei Zheng, Shuhuai Yao

Journal: Biosens Bioelectron

PubMed ID: 34507095

Doi: 10.1016/j.bios.2021.113615

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, Encoding a Pentatricopeptide Repeat Protein, Is Essential for Chloroplast RNA Editing and Biogenesis in Soybean

Authors: Xingxing Feng, Suxin Yang, Yaohua Zhang, Cheng Zhiyuan, Kuanqiang Tang, Guang Li, Hui Yu, Jiantian Leng, Qingyu Wang

Journal: Front Plant Sci

PubMed ID: 34567023

Doi: 10.3389/fpls.2021.690973

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PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection

Authors: Zhenyu Wang, Jing Chen, Xingchen Wu, Dan Ma, Xiaohua Zhang, Ruizhen Li, Cong Han, Haixin Liu, Xiangrui Yin, Qian Du, Dewen Tong, Yong Huang

Journal: PLoS Pathog

PubMed ID: 34543359

Doi: 10.1371/journal.ppat.1009940

Products & Services: Proteins, Expression, Isolation and Analysis

Aptamer/antibody sandwich method for digital detection of SARS-CoV2 nucleocapsid protein

Authors: Chenchen Ge, Juan Feng, Jiaming Zhang, Kai Hu, Dou Wang, Ling Zha, Xuejuan Hu, Rongsong Li

Journal: Talanta

PubMed ID: 34635237

Doi: 10.1016/j.talanta.2021.122847

Products & Services: Proteins, Expression, Isolation and Analysis

Efficient and high-throughput pseudorecombinant-chimeric Cucumber mosaic virus-based VIGS in maize

Authors: Huangai Li, Danfeng Zhang, Ke Xie, Yan Wang, Qiansheng Liao, Yiguo Hong, Yule Liu

Journal: Plant Physiol

PubMed ID: 34606612

Doi: 10.1093/plphys/kiab443

Products & Services: Proteins, Expression, Isolation and Analysis

Shigella ubiquitin ligase IpaH78 targets gasdermin D for degradation to prevent pyroptosis and enable infection

Authors: Giovanni Luchetti, Justin L Roncaioli, Roberto A Chavez, Alexander F Schubert, Eric M Kofoed, Rohit Reja, Tommy K Cheung, Yuxin Liang, Joshua D Webster, Isabelle Lehoux, Elizabeth Skippington, Janina Reeder, Benjamin Haley, Man Wah Tan, Christopher M Rose, Kim Newton, Nobuhiko Kayagaki, Russell E Vance, Vishva M Dixit

Journal: Cell Host Microbe

PubMed ID: 34492225

Doi: 10.1016/j.chom.2021.08.010

Products & Services: Proteins, Expression, Isolation and Analysis

MiR-92d-3p suppresses the progression of diabetic nephropathy renal fibrosis by inhibiting the C3/HMGB1/TGF-β1 pathway

Authors:

Journal: Biosci Rep

PubMed ID: 33729484

Doi: 10.1042/BSR20203131

Products & Services: Proteins, Expression, Isolation and Analysis

Brain-derived extracellular vesicles mediated coagulopathy, inflammation and apoptosis after sepsis

Authors: Huaying Lin, Hongguang Chen, Bo Qi, Yi Jiang, Naqi Lian, Xiaoli Zhuang, Yonghao Yu

Journal: Thromb Res

PubMed ID: 34583153

Doi: 10.1016/j.thromres.2021.09.014

Products & Services: Proteins, Expression, Isolation and Analysis

Novel Small Molecule Growth Inhibitor Affecting Bacterial Outer Membrane Reduces Extraintestinal Pathogenic Escherichia coli (ExPEC) Infection in Avian Model

Authors: Dipak Kathayat, Yosra A Helmy, Loic Deblais, Vishal Srivastava, Gary Closs, Rahul Khupse, Gireesh Rajashekara

Journal: Microbiol Spectr

PubMed ID: 34468186

Doi: 10.1128/Spectrum.00006-21

Products & Services: Proteins, Expression, Isolation and Analysis

Novel c-Jun N-Terminal Kinase (JNK) Inhibitors with an 11-Indeno[1,2-]quinoxalin-11-one Scaffold

Authors: Serhii A Liakhov, Igor A Schepetkin, Olexander S Karpenko, Hanna I Duma, Nadiia M Haidarzhy, Liliya N Kirpotina, Anastasia R Kovrizhina, Andrei I Khlebnikov, Irina Y Bagryanskaya, Mark T Quinn

Journal: Molecules

PubMed ID: 34577159

Doi: 10.3390/molecules26185688

Products & Services: Proteins, Expression, Isolation and Analysis

Assessment of prediction methods for protein structures determined by NMR in CASP14: Impact of AlphaFold2

Authors: Yuanpeng Janet Huang, Ning Zhang, Beate Bersch, Krzysztof Fidelis, Masayori Inouye, Yojiro Ishida, Andriy Kryshtafovych, Naohiro Kobayashi, Yutaka Kuroda, Gaohua Liu, Andy LiWang, G V T Swapna, Nan Wu, Toshio Yamazaki, Gaetano T Montelione

Journal: Proteins

PubMed ID: 34559429

Doi: 10.1002/prot.26246

Products & Services: Proteins, Expression, Isolation and Analysis

Fungal Community Shift Along Steep Environmental Gradients from Geothermal Soils in Yellowstone National Park

Authors: Anna L Bazzicalupo, Sonya Erlandson, Margaret Branine, Megan Ratz, Lauren Ruffing, Nhu H Nguyen, Sara Branco

Journal: Microb Ecol

PubMed ID: 34468785

Doi: 10.1007/s00248-021-01848-y

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MiR-1236-3p Inhibits the Proliferation, Invasion, and Migration of Colon Cancer Cells and Hinders Epithelial-Mesenchymal Transition by Targeting DCLK3

Authors: Yibin Zhao, Hongyi Zhou, Jie Shen, Shaohui Yang, Ke Deng, Qi Li, Wei Cui

Journal: Front Oncol

PubMed ID: 34540665

Doi: 10.3389/fonc.2021.688882

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A sick plot-based protocol for dry root rot disease assessment in field-grown chickpea plants

Authors: Vadivelmurugan Irulappan, Komal Vitthalrao Mali, Basavanagouda S Patil, Hanumappa Manjunatha, Saifulla Muhammad, Muthappa Senthil-Kumar

Journal: Appl Plant Sci

PubMed ID: 34504738

Doi: 10.1002/aps3.11445

Products & Services: DNA Sequencing

Chimeric VLPs Bearing VP60 from Two Serotypes of Are Protective against Both Viruses

Authors: Kevin P Dalton, Carmen Alvarado, Edel Reytor, Maria Del Carmen Nuñez, Ana Podadera, Diego Martínez-Alonso, Jose Manuel Martin Alonso, Ines Nicieza, Silvia Gómez-Sebastián, Romy M Dalton, Francisco Parra, José M Escribano

Journal: Vaccines (Basel)

PubMed ID: 34579243

Doi: 10.3390/vaccines9091005

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Odorant-binding proteins in canine anal sac glands indicate an evolutionarily conserved role in mammalian chemical communication

Authors: Sunita Janssenswillen, Kim Roelants, Sebastien Carpentier, Hilde de Rooster, Mieke Metzemaekers, Bram Vanschoenwinkel, Paul Proost, Franky Bossuyt

Journal: BMC Ecol Evol

PubMed ID: 34565329

Doi: 10.1186/s12862-021-01910-w

Products & Services: DNA Sequencing

Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response

Authors: Jeong A Park, Linlin Wang, Nai-Kong V Cheung

Journal: J Hematol Oncol

PubMed ID: 34496935

Doi: 10.1186/s13045-021-01156-5

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Identification of putative muscarinic acetylcholine receptor genes in Bactrocera dorsalis and functional analysis of Bdor-mAChR-B

Authors: Jian-Fang Li, Xiao-Yu Zhang, Xue Bai, Hong-Ai Su, Ya-Lan Liu, Yong-Yue Lu, Yi-Xiang Qi

Journal: Insect Biochem Mol Biol

PubMed ID: 34582990

Doi: 10.1016/j.ibmb.2021.103657

Products & Services: DNA Sequencing

Insights into the Molecular Mechanisms of Histone Code Recognition by the BRPF3 Bromodomain

Authors: Soumen Barman, Anirban Roy, Ishita Bardhan, Thirukumaran Kandasamy, Shivani Shivani, Babu Sudhamalla

Journal: Chem Asian J

PubMed ID: 34448544

Doi: 10.1002/asia.202100793

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Development of mesothelin-specific CAR NK-92 cells for the treatment of gastric cancer

Authors: Bihui Cao, Manting Liu, Jingjun Huang, Jingwen Zhou, Junping Li, Hui Lian, Wensou Huang, Yongjian Guo, Shuo Yang, Liteng Lin, Mingyue Cai, Cheng Zhi, Jingqiang Wu, Licong Liang, Yuling Hu, Hong Hu, Jinping He, Baoxia Liang, Qi Zhao, Kangshun Zhu

Journal: Int J Biol Sci

PubMed ID: 34671203

Doi: 10.7150/ijbs.64630

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Zoonotic potential of a novel bat morbillivirus

Authors: Benhur Lee, Satoshi Ikegame, Jillian Carmichael, Heather Wells, Robert Furler, Joshua Acklin, Hsin-Ping Chiu, Kasopefoluwa Oguntuyo, Robert Cox, Aum Patel, Shreyas Kowdle, Christian Stevens, Miles Eckley, Shijun Zhan, Jean Lim, Takao Hashiguchi, Edison Luís Durigon, Tony Schountz, Jonathan Epstein, Richard Plemper, Peter Daszak, Simon Anthony

Journal: Res Sq

PubMed ID: 34611656

Doi: 10.21203/rs.3.rs-926789/v1

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Nicotinamide Adenine Dinucleotide-Dependent Flavin Oxidoreductase of Functions as a Potential Novel Virulence Factor and Not Only as a Metabolic Enzyme

Authors: Xing Xie, Fei Hao, Rong Chen, Jingjing Wang, Yanna Wei, Jin Liu, Haiyan Wang, Zhenzhen Zhang, Yun Bai, Guoqing Shao, Qiyan Xiong, Zhixin Feng

Journal: Front Microbiol

PubMed ID: 34671334

Doi: 10.3389/fmicb.2021.747421

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Divergent regulation of inflammatory cytokines by mTORC1 in THP-1-derived macrophages and intestinal epithelial Caco-2 cells

Authors: Harleen Kaur, Anjeza Erickson, Régis Moreau

Journal: Life Sci

PubMed ID: 34478760

Doi: 10.1016/j.lfs.2021.119920

Grass Carp Reovirus VP56 Allies VP4, Recruits, Blocks, and Degrades RIG-I to More Effectively Attenuate IFN Responses and Facilitate Viral Evasion

Authors: Hang Su, Zhiwei Liao, Chunrong Yang, Yongan Zhang, Jianguo Su

Journal: Microbiol Spectr

PubMed ID: 34523975

Doi: 10.1128/Spectrum.01000-21

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Recovery of Memory B-cell Subsets and Persistence of Antibodies in Convalescent COVID-19 Patients

Authors: Anuradha Rajamanickam, Nathella Pavan Kumar, Arul Nancy P, Nandhini Selvaraj, Saravanan Munisankar, Rachel Mariam Renji, Vijayalakshmi V, Manoj Murhekar, Jeromie Wesley Vivian Thangaraj, Muthusamy Santhosh Kumar, C P Girish Kumar, Tarun Bhatnagar, Manickam Ponnaiah, R Sabarinathan, V Saravana Kumar, Subash Babu

Journal: Am J Trop Med Hyg

PubMed ID: 34583334

Doi: 10.4269/ajtmh.21-0883

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Circular RNA ERBB2 Contributes to Proliferation and Migration of Airway Smooth Muscle Cells via miR-98-5p/IGF1R Signaling in Asthma

Authors: Jun-Qian Huang, Fang Wang, Long-Tao Wang, Yong-Mei Li, Jun-Li Lu, Jian-You Chen

Journal: J Asthma Allergy

PubMed ID: 34616159

Doi: 10.2147/JAA.S326058

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Dnj1 Promotes Virulence in by Maintaining Robust Endoplasmic Reticulum Homeostasis Under Temperature Stress

Authors: Linda C Horianopoulos, Christopher W J Lee, Guanggan Hu, Mélissa Caza, James W Kronstad

Journal: Front Microbiol

PubMed ID: 34566931

Doi: 10.3389/fmicb.2021.727039

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Structural basis of an epitope tagging system derived from Haloarcula marismortui bacteriorhodopsin I D94N and its monoclonal antibody GD-26

Authors: Po-Jung Pao, Min-Feng Hsu, Ming-Hui Chiang, Chun-Ting Chen, Cheng-Chung Lee, Andrew H-J Wang

Journal: FEBS J

PubMed ID: 34499806

Doi: 10.1111/febs.16184

Products & Services: Bacterial Expression

Combinations of Single Chain Variable Fragments From HIV Broadly Neutralizing Antibodies Demonstrate High Potency and Breadth

Authors: Rebecca T van Dorsten, Kshitij Wagh, Penny L Moore, Lynn Morris

Journal: Front Immunol

PubMed ID: 34603312

Doi: 10.3389/fimmu.2021.734110

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ER Bodies Are Induced by and Negatively Regulate Immunity

Authors: José S Rufián, James M Elmore, Eduardo R Bejarano, Carmen R Beuzon, Gitta L Coaker

Journal: Mol Plant Microbe Interact

PubMed ID: 34110257

Doi: 10.1094/MPMI-11-20-0330-SC

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Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts

Authors: Anissa A Widjaja, Sivakumar Viswanathan, Dong Jinrui, Brijesh K Singh, Jessie Tan, Joyce Goh Wei Ting, David Lamb, Shamini G Shekeran, Benjamin L George, Sebastian Schafer, David Carling, Eleonora Adami, Stuart A Cook

Journal: Front Mol Biosci

PubMed ID: 34651016

Doi: 10.3389/fmolb.2021.740650

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Fluorometric coupled enzyme assay for N-sulfotransferase activity of N-deacetylase/N-sulfotransferase (NDST)

Authors: Joshua Atienza, Ilona Tkachyova, Michael Tropak, Xiaolian Fan, Andreas Schulze

Journal: Glycobiology

PubMed ID: 34080004

Doi: 10.1093/glycob/cwab048

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Identification of Circular RNAs Related to Vascular Endothelial Proliferation, Migration, and Angiogenesis After Spinal Cord Injury Using Microarray Analysis in Female Mice

Authors: Xin Ye, Yilei Chen, Jiasheng Wang, Jian Chen, Ying Yao, Lin-Lin Wang, Fengdong Zhao

Journal: Front Neurol

PubMed ID: 34539543

Doi: 10.3389/fneur.2021.666750

Products & Services: Proteins, Expression, Isolation and Analysis

Tissue dynamics of von Willebrand factor characterized by a novel fluorescent protein-von Willebrand factor chimera

Authors: Linru Xu, Yanyang Qiu, Yanqing Li, Yaxuan Wei, Yan Wan, Wei Deng

Journal: J Thromb Haemost

PubMed ID: 34592034

Doi: 10.1111/jth.15542

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Parasitic modulation of host development by ubiquitin-independent protein degradation

Authors: Weijie Huang, Allyson M MacLean, Akiko Sugio, Abbas Maqbool, Marco Busscher, Shu-Ting Cho, Sophien Kamoun, Chih-Horng Kuo, Richard G H Immink, Saskia A Hogenhout

Journal: Cell

PubMed ID: 34536345

Doi: 10.1016/j.cell.2021.08.029

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Bacterial Cytological Profiling Identifies Rhodanine-Containing PAINS Analogs as Specific Inhibitors of Thymidylate Kinase

Authors: Elizabeth T Montaño, Jason F Nideffer, Joseph Sugie, Eray Enustun, Adam B Shapiro, Hannah Tsunemoto, Alan I Derman, Kit Pogliano, Joe Pogliano

Journal: J Bacteriol

PubMed ID: 34280002

Doi: 10.1128/JB.00105-21

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Characterization of a Novel Shewanella algae Arginine Decarboxylase Expressed in Escherichia coli

Authors: Xiao-Dong Pei, Liang-Hua Lu, Shi-Yang Yue, Ya Li, Xiao-Ling Liu, Fan Li, Ke-Jie Wu, Cheng-Hua Wang

Journal: Mol Biotechnol

PubMed ID: 34532832

Doi: 10.1007/s12033-021-00397-6

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Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction

Authors: Kristopher A Knight, Christopher W Coyle, Caelan E Radford, Ernest T Parker, Andrew Fedanov, Jordan M Shields, Fania Szlam, Anatolii Purchel, Michelle Chen, Gabriela Denning, Roman M Sniecinski, Pete Lollar, H Trent Spencer, Eric A Gaucher, Christopher B Doering

Journal: Blood Adv

PubMed ID: 34477814

Doi: 10.1182/bloodadvances.2021004742

Products & Services: PCR Cloning and Subcloning

The increased presence of repetitive motifs in the KDDR-plus recombinant protein, a kinesin-derived antigen from Leishmania infantum, improves the diagnostic performance of serological tests for human and canine visceral leishmaniasis

Authors: Williane Fernanda Siqueira, Agostinho Gonçalves Viana, João Luís Reis Cunha, Leticia Mansur Rosa, Lilian Lacerda Bueno, Daniella Castanheira Bartholomeu, Mariana Santos Cardoso, Ricardo Toshio Fujiwara

Journal: PLoS Negl Trop Dis

PubMed ID: 34534217

Doi: 10.1371/journal.pntd.0009759

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The EDS1-PAD4-ADR1 node mediates Arabidopsis pattern-triggered immunity

Authors: Rory N Pruitt, Federica Locci, Friederike Wanke, Lisha Zhang, Svenja C Saile, Anna Joe, Darya Karelina, Chenlei Hua, Katja Fröhlich, Wei-Lin Wan, Meijuan Hu, Shaofei Rao, Sara C Stolze, Anne Harzen, Andrea A Gust, Klaus Harter, Matthieu H A J Joosten, Bart P H J Thomma, Jian-Min Zhou, Jeffery L Dangl, Detlef Weigel, Hirofumi Nakagami, Claudia Oecking, Farid El Kasmi, Jane E Parker, Thorsten Nürnberger

Journal: Nature

PubMed ID: 34497423

Doi: 10.1038/s41586-021-03829-0

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Thioredoxin reductase from Bacillus cereus exhibits distinct reduction and NADPH-binding properties

Authors: Marita Shoor, Ingvild Gudim, Hans-Petter Hersleth, Marta Hammerstad

Journal: FEBS Open Bio

PubMed ID: 34492167

Doi: 10.1002/2211-5463.13289

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Epitope-dependent thermodynamic signature of single-domain antibodies against hen egg lysozyme

Authors: Hiroki Akiba, Hiroko Tamura, Jose M M Caaveiro, Kouhei Tsumoto

Journal: J Biochem

PubMed ID: 34519785

Doi: 10.1093/jb/mvab082

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Crus2 Glycine-Rich Region Contributes Largely to the Antiviral Activity of the Whole-Protein Molecule by Interacting with VP26, a WSSV Structural Protein

Authors: Yue Wang, Chao Zhang, Wen-Hong Fang, Hong-Yu Ma, Xin-Cang Li

Journal: Mar Drugs

PubMed ID: 34677443

Doi: 10.3390/md19100544

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The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation

Authors: Linyu Sun, Wentao Wang, Cai Han, Wei Huang, Yumeng Sun, Ke Fang, Zhancheng Zeng, Qianqian Yang, Qi Pan, Tianqi Chen, Xuequn Luo, Yueqin Chen

Journal: Mol Cell

PubMed ID: 34555354

Doi: 10.1016/j.molcel.2021.08.033

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YAP facilitates melanoma migration through regulation of actin-related protein 2/3 complex subunit 5 (ARPC5)

Authors: Jason W Lui, Stephen P G Moore, Lee Huang, Kelsey Ogomori, Yan Li, Deborah Lang

Journal: Pigment Cell Melanoma Res

PubMed ID: 34468072

Doi: 10.1111/pcmr.13013

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LCZ696 Possesses a Protective Effect Against Homocysteine (Hcy)-Induced Impairment of Blood-Brain Barrier (BBB) Integrity by Increasing Occludin, Mediated by the Inhibition of Egr-1

Authors: Wenfeng Li, Wenjin Yuan, Dandan Zhang, Shuchun Cai, Jun Luo, Kanghua Zeng

Journal: Neurotox Res

PubMed ID: 34542838

Doi: 10.1007/s12640-021-00414-1

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Critical Conditions for Studying Interleukin-11 Signaling In Vitro and Avoiding Experimental Artefacts

Authors: Sivakumar Viswanathan, Benjamin Ng, Anissa A Widjaja, Chee Jian Pua, Nevin Tham, Jessie Tan, Stuart A Cook, Sebastian Schafer

Journal: Curr Protoc

PubMed ID: 34570432

Doi: 10.1002/cpz1.251

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Two evolutionarily duplicated domains individually and post-transcriptionally control SWEET expression for phloem transport

Authors: Chen Zhang, Ye Li, Jiang Wang, Xueyi Xue, Gabriel Beuchat, Li-Qing Chen

Journal: New Phytol

PubMed ID: 34431115

Doi: 10.1111/nph.17688

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The E3 Ubiquitin Ligase TRIM25 Inhibits Tembusu Virus Replication

Authors: Han Kaikai, Dongmin Zhao, Yuzhuo Liu, Qingtao Liu, Xinmei Huang, Jing Yang, Lijiao Zhang, Yin Li

Journal: Front Vet Sci

PubMed ID: 34595229

Doi: 10.3389/fvets.2021.722113

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Estrogen-regulated AGR3 activates the estrogen receptor signaling pathway to promote tamoxifen resistance in breast cancer

Authors: Rui Jiang, Yongjie Sun, Xiao Chen, Peng Shi

Journal: Breast Cancer Res Treat

PubMed ID: 34519905

Doi: 10.1007/s10549-021-06385-3

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Overexpression of arogenate dehydratase reveals an upstream point of metabolic control in phenylalanine biosynthesis

Authors: Heejin Yoo, Stuti Shrivastava, Joseph H Lynch, Xing-Qi Huang, Joshua R Widhalm, Longyun Guo, Benjamin C Carter, Yichun Qian, Hiroshi A Maeda, Joseph P Ogas, John A Morgan, Amy Marshall-Colón, Natalia Dudareva

Journal: Plant J

PubMed ID: 34403557

Doi: 10.1111/tpj.15467

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Quorum Sensing by Gelsolin Regulates Programmed Cell Death 4 Expression and a Density-Dependent Phenotype in Macrophages

Authors: Reshma Kumari Sharma, Binita Goswami, Sukhen Das Mandal, Abhishek Guha, Belinda Willard, Partho Sarothi Ray

Journal: J Immunol.

PubMed ID: 34362832

Doi: 10.4049/jimmunol.2001392

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Molecular basis for kinin selectivity and activation of the human bradykinin receptors

Authors: Yu-Ling Yin, Chenyu Ye, Fulai Zhou, Jia Wang, Dehua Yang, Wanchao Yin, Ming-Wei Wang, H Eric Xu, Yi Jiang

Journal: Nat Struct Mol Biol .

PubMed ID: 34518695

Doi: 10.1038/s41594-021-00645-y

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BORIS/CTCFL expression activates the TGFβ signaling cascade and induces Drp1 mediated mitochondrial fission in neuroblastoma

Authors: Venkata Krishna Kanth Makani, Jolly Janette Mendonza, Prajitha Mohandas Edathara, Suresh Yerramsetty, Manika Pal Bhadra

Journal: Free Radic Biol Med

PubMed ID: 34534628

Doi: 10.1016/j.freeradbiomed.2021.09.010

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The Fish Pathogen Aliivibrio salmonicida LFI1238 Can Degrade and Metabolize Chitin despite Gene Disruption in the Chitinolytic Pathway

Authors: Anna Skåne, Giusi Minniti, Jennifer S M Loose, Sophanit Mekasha, Bastien Bissaro, Geir Mathiesen, Magnus Ø Arntzen, Gustav Vaaje-Kolstad

Journal: Appl Environ Microbiol

PubMed ID: 34319813

Doi: 10.1128/AEM.00529-21

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Mechanisms of reducing joint stiffness by blocking collagen fibrillogenesis in a rabbit model of posttraumatic arthrofibrosis

Authors: Andrzej Steplewski, Jolanta Fertala, Ryan E Tomlinson, Mark L Wang, Allison Donahue, William V Arnold, Michael Rivlin, Pedro K Beredjiklian, Joseph A Abboud, Surena Namdari, Andrzej Fertala

Journal: PLoS ONE

PubMed ID: 34492074

Doi: 10.1371/journal.pone.0257147

Products & Services: Proteins, Expression, Isolation and Analysis

IgG Antibodies Develop to Spike but Not to the Nucleocapsid Viral Protein in Many Asymptomatic and Light COVID-19 Cases

Authors: Maria Tutukina, Anna Kaznadzey, Maria Kireeva, Ilya Mazo

Journal: Viruses

PubMed ID: 34696374

Doi: 10.3390/v13101945

Products & Services: Mammalian Expression

Validation of an insertion-engineered isoprene synthase as a strategy to functionalize terpene synthases

Authors: C Raul Gonzalez-Esquer, Bryan Ferlez, Sarathi M Weraduwage, Henning Kirst, Alexandra T Lantz, Aiko Turmo, Thomas D Sharkey, Cheryl A Kerfeld

Journal: RSC Adv

PubMed ID: 35480253

Doi: 10.1039/d1ra05710c

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