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The Slower Antibody Response in Myelofibrosis Patients after Two Doses of mRNA SARS-CoV-2 Vaccine Calls for a Third Dose

Authors: Fabio Fiorino, Anna Sicuranza, Annalisa Ciabattini, Adele Santoni, Gabiria Pastore, Martina Simoncelli, Jacopo Polvere, Sara Galimberti, Stefano Auddino, Claudia Baratè, Francesca Montagnani, Vincenzo Sammartano, Monica Bocchia, Donata Medaglini

Journal: Biomedicines

PubMed ID: 34680595

Doi: 10.3390/biomedicines9101480

Determination Factors Associated with Immune Responses Towards First Dose Edmonston-Zagreb (EZ) Measles Vaccine in Indonesian Infants

Authors: H R Teni Nurlatifah, Wisnu Barlianto, Wayan Arsana Wiyasa, Chandra Kusuma, Tita Luthfia Sari, Novilia Sjafri Bachtiar

Journal: Med Arch

PubMed ID: 35169353

Doi: 10.5455/medarh.2021.75.335-339

Products & Services: Catalog Peptides

Determination Factors Associated with Immune Responses Towards First Dose Edmonston-Zagreb (EZ) Measles Vaccine in Indonesian Infants

Authors: H R Teni Nurlatifah, Wisnu Barlianto, Wayan Arsana Wiyasa, Chandra Kusuma, Tita Luthfia Sari, Novilia Sjafri Bachtiar

Journal: Med Arch

PubMed ID: 35169353

Doi: 10.5455/medarh.2021.75.335-339

Products & Services: Catalog Peptides

Anticancer properties of colicin E7 against colon cancer

Authors: Morovat Taherikalani, Sobhan Ghafourian

Journal: Prz Gastroenterol

PubMed ID: 34976246

Doi: 10.5114/pg.2021.109622

Products & Services: Custom DNA/RNA Oligos

A dedicated flavin-dependent monooxygenase catalyzes the hydroxylation of demethoxyubiquinone into ubiquinone (coenzyme Q) in Arabidopsis

Authors: Scott Latimer, Shea A Keene, Lauren R Stutts, Antoine Berger, Ann C Bernert, Eric Soubeyrand, Janet Wright, Catherine F Clarke, Anna K Block, Thomas A Colquhoun, Christian Elowsky, Alan Christensen, Mark A Wilson, Gilles J Basset

Journal: J Biol Chem

PubMed ID: 34626646

Doi: 10.1016/j.jbc.2021.101283

Products & Services: Gene Synthesis

Enhanced bone regeneration via spatiotemporal and controlled delivery ofa genetically engineered BMP-2 in a composite Hydrogel

Authors: Xin Chen , Baoyu Tan , Zhiteng Bao , Shang Wang , Rongze Tang , Zhenmin Wang , Gaoyang Chen , Shuai Chen , William W Lu , Dazhi Yang , Songlin Peng

Journal: Biomaterials

PubMed ID: 34517277

Doi: doi.org/10.1016/j.biomaterials.2021.121117

Products & Services: Codon Optimization

Mitoxantrone dihydrochloride, an FDA approved drug, binds with SARS-CoV-2 NSP1 C-terminal

Authors: Prateek Kumar, ProfileTaniya Bhardwaj, ProfileRajanish Giri

Journal: biorxiv

Doi: doi.org/10.1101/2021.09.14.460211

Products & Services: Peptide Synthesis

Orthogonal CRISPR-associated transposases for parallel and multiplexed chromosomal integration

Authors: Siqi Yang, Yiwen Zhang, Jiaqi Xu, Jiao Zhang, Jieze Zhang, Junjie Yang, Yu Jiang, Sheng Yang

Journal: Nucleic Acids Res

PubMed ID: 34478496

Doi: 10.1093/nar/gkab752

Products & Services: Synthetic sgRNA and crRNA Service

Regulation of human mTOR complexes by DEPTOR

Authors: Matthias Wälchli, Karolin Berneiser, Francesca Mangia, Stefan Imseng, Louise-Marie Craigie, Edward Stuttfeld, Michael N Hall, Timm Maier

Journal: Elife

PubMed ID: 34519268

Doi: 10.7554/eLife.70871

Products & Services: Proteins, Expression, Isolation and Analysis

Pre-pandemic SARS-CoV-2 serological reactivity in rural malaria-experienced Cambodians

Authors: Jessica Manning, Irfan Zaidi, Chanthap Lon, Luz Angela Rosas, Jae-Keun Park, Aiyana Ponce, Jennifer Bohl, Sophana Chea, Maria Karkanitsa, Sokunthea Sreng, Huy Rekol, Char Meng Chour, Dominic Esposito, Jeffery K Taubenberger, Matthew J Memoli, Kaitlyn Sadtler, Patrick E Duffy, Fabiano Oliveira

Journal: medrxiv

PubMed ID: 34611671

Doi: 10.1101/2021.09.27.21264000

Products & Services: Proteins, Expression, Isolation and Analysis

Analytical and clinical performance of cPass neutralizing antibodies assay

Authors: Joanna Jung, Deepthi Rajapakshe, Christopher Julien, Sridevi Devaraj

Journal: Clin Biochem

PubMed ID: 34560062

Doi: 10.1016/j.clinbiochem.2021.09.008

Products & Services: Proteins, Expression, Isolation and Analysis

Kinase-Catalyzed Biotinylation to Map Cell Signaling Pathways: Application to Epidermal Growth Factor Signaling

Authors: Vindya Ramanayake-Mudiyanselage, D Maheeka Embogama, Mary Kay H Pflum

Journal: J Proteome Res

PubMed ID: 34491762

Doi: 10.1021/acs.jproteome.1c00562

Products & Services: Proteins, Expression, Isolation and Analysis

A Small Cysteine-Rich Phytotoxic Protein of Functions as Both Plant Defense Elicitor and Virulence Factor

Authors: Zi-Hui Zhang, Jing-Hao Jin, Gui-Lin Sheng, Yu-Ping Xing, Wang Liu, Xue Zhou, Yi-Qing Liu, Xiao-Ren Chen

Journal: Mol Plant Microbe Interact

PubMed ID: 33819070

Doi: 10.1094/MPMI-01-21-0025-R

Products & Services: Proteins, Expression, Isolation and Analysis

A Closer Look into FDA-EUA Approved Diagnostic Techniques of Covid-19

Authors: Hyunju Oh, Hyunjeong Ahn, Anubhav Tripathi

Journal: ACS Infect Dis

PubMed ID: 34569778

Doi: 10.1021/acsinfecdis.1c00268

Products & Services: Proteins, Expression, Isolation and Analysis

Consumption of gossypol increases fatty acid-amino acid conjugates in the cotton pests Helicoverpa armigera and Heliothis virescens

Authors: Corinna Krempl, Nicole Joußen, Michael Reichelt, Marco Kai, Heiko Vogel, David G Heckel

Journal: Arch Insect Biochem Physiol

PubMed ID: 34490676

Doi: 10.1002/arch.21843

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a nanobody-based competitive ELISA for efficiently and specifically detecting antibodies against genotype 2 porcine reproductive and respiratory syndrome viruses

Authors: Hong Duan, Xu Chen, Jiakai Zhao, Jiahong Zhu, Guixi Zhang, Mengnan Fan, Beibei Zhang, Xueting Wang, Yani Sun, Baoyuan Liu, En-Min Zhou, Qin Zhao

Journal: J Clin Microbiol

PubMed ID: 34524888

Doi: 10.1128/JCM.01580-21

Products & Services: DNA Sequencing

The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs

Authors: Lung-Yu Liang, Michael Roy, Christopher R Horne, Jarrod J Sandow, Minglyanna Surudoi, Laura F Dagley, Samuel N Young, Toby Dite, Jeffrey J Babon, Peter W Janes, Onisha Patel, James M Murphy, Isabelle S Lucet

Journal: Biochem J

PubMed ID: 34431498

Doi: 10.1042/BCJ20210572

Products & Services: DNA Sequencing

Genic male sterility increases rice drought tolerance

Authors: Jianyu Wen, Yafei Zeng, Yunping Chen, Fengfeng Fan, Shaoqing Li

Journal: Plant Sci

PubMed ID: 34620451

Doi: 10.1016/j.plantsci.2021.111057

Products & Services: Custom Vector Construction

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69

Authors: Jonas Persson, Emmi Puuvuori, Bo Zhang, Irina Velikyan, Ola Åberg, Malin Müller, Per-Åke Nygren, Stefan Ståhl, Olle Korsgren, Olof Eriksson, John Löfblom

Journal: Sci Rep

PubMed ID: 34580321

Doi: 10.1038/s41598-021-97694-6

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Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants

Authors: Tingting Li, Wenhui Xue, Qingbing Zheng, Shuo Song, Chuanlai Yang, Hualong Xiong, Sibo Zhang, Minqing Hong, Yali Zhang, Hai Yu, Yuyun Zhang, Hui Sun, Yang Huang, Tingting Deng, Xin Chi, Jinjin Li, Shaojuan Wang, Lizhi Zhou, Tingting Chen, Yingbin Wang, Tong Cheng, Tianying Zhang, Quan Yuan, Qinjian Zhao, Jun Zhang, Jason S McLellan, Z Hong Zhou, Zheng Zhang, Shaowei Li, Ying Gu, Ningshao Xia

Journal: Nat Commun

PubMed ID: 34580306

Doi: 10.1038/s41467-021-25997-3

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Diffusion of a disordered protein on its folded ligand

Authors: Felix Wiggers, Samuel Wohl, Artem Dubovetskyi, Gabriel Rosenblum, Wenwei Zheng, Hagen Hofmann

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34504002

Doi: 10.1073/pnas.2106690118

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Sorting nexin 6 interacts with Cullin3 and regulates programmed death ligand 1 expression

Authors: Chinmoy Ghosh, Yanli Xing, Suhua Li, Rosalie G Hoyle, Ming Sun, Jiong Li, Yue Sun

Journal: FEBS Lett

PubMed ID: 34510437

Doi: 10.1002/1873-3468.14191

Products & Services: Custom Vector Construction

Pathways of thymidine hypermodification

Authors: Yan-Jiun Lee, Nan Dai, Stephanie I Müller, Chudi Guan, Mackenzie J Parker, Morgan E Fraser, Shannon E Walsh, Janani Sridar, Andrew Mulholland, Krutika Nayak, Zhiyi Sun, Yu-Cheng Lin, Donald G Comb, Katherine Marks, Reyaz Gonzalez, Daniel P Dowling, Vahe Bandarian, Lana Saleh, Ivan R Corrêa, Peter R Weigele

Journal: Nucleic Acids Res

PubMed ID: 34522950

Doi: 10.1093/nar/gkab781

Products & Services: Codon Optimization

A Novel Miniature CRISPR-Cas13 System for SARS-CoV-2 Diagnostics

Authors: Ahmed Mahas, Qiaochu Wang, Tin Marsic, Magdy M Mahfouz

Journal: ACS Synth Biol

PubMed ID: 34546709

Doi: 10.1021/acssynbio.1c00181

Products & Services: Codon Optimization

Controlling the Orientation and Viscoelasticity of Materials-Binding Peptides on Hexagonal Boron Nitride Using Fatty Acids

Authors: Nermina Brljak, Marc R Knecht, Tiffany R Walsh

Journal: J Phys Chem B

PubMed ID: 34505506

Doi: 10.1021/acs.jpcb.1c05446

Products & Services: Catalog Peptides

In-yeast reconstruction of the African swine fever virus genome isolated from clinical samples

Authors: Fabien Labroussaa, Kemal Mehinagic, Valentina Cippa, Matthias Liniger, Hatice Akarsu, Nicolas Ruggli, Joerg Jores

Journal: STAR Protoc

PubMed ID: 34527959

Doi: 10.1016/j.xpro.2021.100803

Products & Services: Recombinant Proteins

Serological Testing Reveals the Hidden COVID-19 Burden among Health Care Workers Experiencing a SARS-CoV-2 Nosocomial Outbreak

Authors: Yu Nakagama, Yuko Komase, Katherine Candray, Sachie Nakagama, Fumiaki Sano, Tomoya Tsuchida, Hiroyuki Kunishima, Takumi Imai, Ayumi Shintani, Yuko Nitahara, Natsuko Kaku, Yasutoshi Kido

Journal: Microbiol Spectr

PubMed ID: 34550021

Doi: 10.1128/Spectrum.01082-21

Products & Services: Catalog Antibody

Hybrid fusion protein as a dual protease inhibitor for the healing of chronic wounds

Authors: Graham Strauss, Piyush Koria

Journal: Biotechnol Prog

PubMed ID: 34486249

Doi: 10.1002/btpr.3209

Products & Services: Gene Synthesis

Interferon-λ Improves the Efficacy of Intranasally or Rectally Administered Influenza Subunit Vaccines by a Thymic Stromal Lymphopoietin-Dependent Mechanism

Authors: Liang Ye, Daniel Schnepf, Annette Ohnemus, Li Ching Ong, Hans Henrik Gad, Rune Hartmann, Nils Lycke, Peter Staeheli

Journal: Front Immunol

PubMed ID: 34659250

Doi: 10.3389/fimmu.2021.749325

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Coiled coil exposure and histidine tags drive function of an intracellular protein drug carrier

Authors: Anshul Dhankher, Wei Lv, William T Studstill, Julie A Champion

Journal: J Control Release

PubMed ID: 34563592

Doi: 10.1016/j.jconrel.2021.09.026

Products & Services: Gene Synthesis

Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts

Authors: Yi Yu, Lishan Jiang, Jingwen Li, Lang Lei, Houxuan Li

Journal: J Periodontol

PubMed ID: 34585393

Doi: 10.1002/JPER.21-0227

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Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs

Authors: Jesús Horacio Lara-Puente, Juan Manuel Carreño, Weina Sun, Alejandro Suárez-Martínez, Luis Ramírez-Martínez, Francisco Quezada-Monroy, Georgina Paz-De la Rosa, Rosalía Vigueras-Moreno, Gagandeep Singh, Oscar Rojas-Martínez, Héctor Elías Chagoya-Cortés, David Sarfati-Mizrahi, Ernesto Soto-Priante, Constantino López-Macías, Florian Krammer, Felipa Castro-Peralta, Peter Palese, Adolfo García-Sastre, Bernardo Lozano-Dubernard

Journal: MBio

PubMed ID: 34544278

Doi: 10.1128/mBio.01908-21

Products & Services: Gene Synthesis

Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes

Authors: Antoine Baudin, Alma K Moreno-Romero, Xiaoping Xu, Emily E Selig, Luiz O F Penalva, David S Libich

Journal: Front Mol Biosci

PubMed ID: 34631798

Doi: 10.3389/fmolb.2021.744707

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Post-transcriptional screen of cancer amplified genes identifies ERBB2/Her2 signaling as AU-rich mRNA stability-promoting pathway

Authors: Jenan Al-Matouq, Latifa Al-Haj, Maher Al-Saif, Khalid S A Khabar

Journal: Oncogenesis

PubMed ID: 34535639

Doi: 10.1038/s41389-021-00351-w

Products & Services: Polyclonal Antibody Services

Deletion of type VIII collagen reduces blood pressure, increases carotid artery functional distensibility and promotes elastin deposition

Authors: Amanda L Mohabeer, Jeffrey T Kroetsch, Meghan McFadden, Negin Khosraviani, Thomas J Broekelmann, Guangpei Hou, Hangjun Zhang, Yu-Qing Zhou, Minyao Wang, Anthony O Gramolini, Robert P Mecham, Scott P Heximer, Steffen-Sebastian Bolz, Michelle P Bendeck

Journal: Matrix Biol Plus

PubMed ID: 34693248

Doi: 10.1016/j.mbplus.2021.100085

Products & Services: Plasmid DNA Preparation

ReScribe: An Unrestrained Tool Combining Multiplex Recombineering and Minimal-PAM ScCas9 for Genome Recoding

Authors: Enrique Asin-Garcia, Maria Martin-Pascual, Luis Garcia-Morales, Richard van Kranenburg, Vitor A P Martins Dos Santos

Journal: ACS Synth Biol

PubMed ID: 34547891

Doi: 10.1021/acssynbio.1c00297

Products & Services: Plasmid DNA Preparation

MicroRNA-361 reduces the viability and migratory ability of pancreatic cancer cells via mediation of the MAPK/JNK pathway

Authors: Juan Wang, Zongjing Xie, Yan Liu, Weiguo Zhang, Tingting Ji

Journal: Exp Ther Med

PubMed ID: 34659511

Doi: 10.3892/etm.2021.10799

Products & Services: Plasmid DNA Preparation

Yeast Translational Activator Mss51p and Human ZMYND17 - Two Proteins with a Common Origin, but Different Functions

Authors: Maria V Baleva, Uliyana E Piunova, Ivan V Chicherin, Darya G Krasavina, Sergey A Levitskii, Piotr A Kamenski

Journal: Biochemistry (Mosc)

PubMed ID: 34565318

Doi: 10.1134/S0006297921090108

Products & Services: Plasmid DNA Preparation

Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase

Authors: Xida Zhao, Jingbo Liu, Chong Zhang, Ning Yu, Ze Lu, Shuwei Zhang, Yuchao Li, Qian Li, Junchao Liu, Dongjuan Liu, Yaping Pan

Journal: Int J Oral Sci

PubMed ID: 34593756

Doi: 10.1038/s41368-021-00136-2

Products & Services: Plasmid DNA Preparation

CLE14 functions as a "brake signal" to suppress age-dependent and stress-induced leaf senescence by promoting JUB1-mediated ROS scavenging in Arabidopsis

Authors: Zenglin Zhang, Cheng Liu, Kui Li, Xiaoxu Li, Mengmeng Xu, Yongfeng Guo

Journal: Mol Plant

PubMed ID: 34530165

Doi: 10.1016/j.molp.2021.09.006

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Enhancing Antigen Presentation and Inducing Antigen-Specific Immune Tolerance with Amphiphilic Peptides

Authors: Meng Li, Arata Itoh, Jingchao Xi, Chunsong Yu, Yuehong Wu, William M Ridgway, Haipeng Liu

Journal: J Immunol

PubMed ID: 34526376

Doi: 10.4049/jimmunol.1901301

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Characterization of HLA-A*02:01 MHC Immunopeptide Antigens Enhanced by Ultraviolet Photodissociation Mass Spectrometry

Authors: Eleanor Watts, Gregory K Potts, Damien B Ready, Alayna M George Thompson, Janice Lee, Edwin E Escobar, Melanie J Patterson, Jennifer S Brodbelt

Journal: Anal Chem

PubMed ID: 34553926

Doi: 10.1021/acs.analchem.1c01002

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Metformin inhibits hepatocellular carcinoma development by inducing apoptosis and pyroptosis through regulating FOXO3

Authors: Zetian Shen, Han Zhou, Aomei Li, Tiancong Wu, Xiaoqin Ji, Lei Guo, Xixu Zhu, Dagan Zhang, Xia He

Journal: Aging (Albany NY)

PubMed ID: 34546972

Doi: 10.18632/aging.203464

Products & Services: PCR Cloning and Subcloning

Bioinformatics Analysis of a Functional ANGPT1 Variant That Interferes with miR-607 and Its Association with Susceptibility and Outcome of Ischemic Stroke in a Han Population

Authors: Ai-Nian Chen, Ling-Ling Zhong, Ke-Ju Ju, Hua Cao

Journal: Ther Clin Risk Manag

PubMed ID: 34611404

Doi: 10.2147/TCRM.S328964

Products & Services: PCR Cloning and Subcloning

A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC

Authors: M Verónica López, Sabrina E Vinzón, Eduardo G A Cafferata, Felipe J Núñez, Ariadna Soto, Maximiliano Sanchez-Lamas, M Jimena Afonso, Diana Aguilar-Cortes, Gregorio D Ríos, Juliana T Maricato, Carla T Braconi, Vanessa B Silveira, Tatiane M Andrad, Tatiana C S Bonetti, Luiz M Ramos Janini, Manoel J B C Girão, Andrea S Llera, Karina A Gomez, Hugo H Ortega, Paula M Berguer, Osvaldo L Podhajcer

Journal: Vaccines (Basel)

PubMed ID: 34696219

Doi: 10.3390/vaccines9101106

Products & Services: PCR Cloning and Subcloning

ORF3a Protein of Severe Acute Respiratory Syndrome Coronavirus 2 Inhibits Interferon-Activated Janus Kinase/Signal Transducer and Activator of Transcription Signaling Elevating Suppressor of Cytokine Signaling 1

Authors: Rong Wang, Xiaofeng Yang, Mingke Chang, Ziyang Xue, Weirong Wang, Liang Bai, Sihai Zhao, Enqi Liu

Journal: Front Microbiol

PubMed ID: 34650546

Doi: 10.3389/fmicb.2021.752597

Products & Services: ORF cDNA Clones/MolecularCloud

Plant Viral Nanoparticle Conjugated with Anti-PD-1 Peptide for Ovarian Cancer Immunotherapy

Authors: Aayushma Gautam, Veronique Beiss, Chao Wang, Lu Wang, Nicole F Steinmetz

Journal: Int J Mol Sci

PubMed ID: 34575893

Doi: 10.3390/ijms22189733

Products & Services: ORF cDNA Clones/MolecularCloud

The tumor suppressor miR-642a-5p targets Wilms Tumor 1 gene and cell-cycle progression in prostate cancer

Authors: Dianne J Beveridge, Kirsty L Richardson, Michael R Epis, Rikki A M Brown, Lisa M Stuart, Andrew J Woo, Peter J Leedman

Journal: Sci Rep

PubMed ID: 34504167

Doi: 10.1038/s41598-021-97190-x

Products & Services: ORF cDNA Clones/MolecularCloud

Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder

Authors: Luke Kowal, Jianhe Huang, Hongbin Luo, Jagmohan Singh, Adam E Snook, Jouni Uitto, Qiaoli Li

Journal: J Invest Dermatol

PubMed ID: 34597610

Doi: 10.1016/j.jid.2021.08.435

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complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity

Authors: Shinichi Fukuda, Siddharth Narendran, Akhil Varshney, Yosuke Nagasaka, Shao-Bin Wang, Kameshwari Ambati, Ivana Apicella, Felipe Pereira, Benjamin J Fowler, Tetsuhiro Yasuma, Shuichiro Hirahara, Reo Yasuma, Peirong Huang, Praveen Yerramothu, Ryan D Makin, Mo Wang, Kirstie L Baker, Kenneth M Marion, Xiwen Huang, Elmira Baghdasaryan, Meenakshi Ambati, Vidya L Ambati, Daipayan Banerjee, Vera L Bonilha, Genrich V Tolstonog, Ulrike Held, Yuichiro Ogura, Hiroko Terasaki, Tetsuro Oshika, Deepak Bhattarai, Kyung Bo Kim, Sanford H Feldman, J Ignacio Aguirre, David R Hinton, Nagaraj Kerur, Srinivas R Sadda, Gerald G Schumann, Bradley D Gelfand, Jayakrishna Ambati

Journal: Sci Adv

PubMed ID: 34586848

Doi: 10.1126/sciadv.abj3658

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TRIM25 inhibits infectious bursal disease virus replication by targeting VP3 for ubiquitination and degradation

Authors: Suyan Wang, Mengmeng Yu, Aijing Liu, Yuanling Bao, Xiaole Qi, Li Gao, Yuntong Chen, Peng Liu, Yulong Wang, Lixiao Xing, Lingzhai Meng, Yu Zhang, Linjin Fan, Xinyi Li, Qing Pan, Yanping Zhang, Hongyu Cui, Kai Li, Changjun Liu, Xijun He, Yulong Gao, Xiaomei Wang

Journal: PLoS Pathog

PubMed ID: 34516573

Doi: 10.1371/journal.ppat.1009900

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CCD2 Access Tunnel Design for a Broader Substrate Profile in Crocetin Production

Authors: Nan Liang, Ming-Dong Yao, Ying Wang, Jia Liu, Lu Feng, Zhi-Ming Wang, Xiang-Yu Li, Wen-Hai Xiao, Ying-Jin Yuan

Journal: J Agric Food Chem

PubMed ID: 34554747

Doi: 10.1021/acs.jafc.1c04588

Products & Services: Mutagenesis Services

Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant

Authors: Laura T Gray, Michal M Raczy, Priscilla S Briquez, Tiffany M Marchell, Aaron T Alpar, Rachel P Wallace, Lisa R Volpatti, Maria Stella Sasso, Shijie Cao, Mindy Nguyen, Aslan Mansurov, Erica Budina, Elyse A Watkins, Ani Solanki, Nikolaos Mitrousis, Joseph W Reda, Shann S Yu, Andrew C Tremain, Ruyi Wang, Vlad Nicolaescu, Kevin Furlong, Steve Dvorkin, Balaji Manicassamy, Glenn Randall, D Scott Wilson, Marcin Kwissa, Melody A Swartz, Jeffrey A Hubbell

Journal: Biomaterials

PubMed ID: 34634664

Doi: 10.1016/j.biomaterials.2021.121159

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Polydopamine nanoparticles with different sizes for NIR-promoted gene delivery and synergistic photothermal therapy

Authors: Peng Zhang, Xinfang Li, Qinan Xu, Youxiang Wang, Jian Ji

Journal: Colloids Surf B Biointerfaces

PubMed ID: 34601352

Doi: 10.1016/j.colsurfb.2021.112125

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Ceramide Regulates Anti-Tumor Mechanisms of Erianin in Androgen-Sensitive and Castration-Resistant Prostate Cancers

Authors: I Gusti Md Gde Surya C Trapika, Xin Tracy Liu, Long Hoa Chung, Felcia Lai, Chanlu Xie, Yang Zhao, Shaohui Cui, Jinbiao Chen, Collin Tran, Qian Wang, Shubiao Zhang, Anthony S Don, George Qian Li, Jane R Hanrahan, Yanfei Qi

Journal: Front Oncol

PubMed ID: 34604081

Doi: 10.3389/fonc.2021.738078

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Impaired Antibody-Dependent Cellular Cytotoxicity in a Spanish Cohort of Patients With COVID-19 Admitted to the ICU

Authors: Lorena Vigón, Javier García-Pérez, Sara Rodríguez-Mora, Montserrat Torres, Elena Mateos, María Castillo de la Osa, Miguel Cervero, Rosa Malo De Molina, Cristina Navarro, María Aránzazu Murciano-Antón, Valentín García-Gutiérrez, Vicente Planelles, José Alcamí, Mayte Pérez-Olmeda, Mayte Coiras, María Rosa López-Huertas

Journal: Front Immunol

PubMed ID: 34616404

Doi: 10.3389/fimmu.2021.742631

Products & Services: Mammalian Expression

Bitter Taste Receptor T2R14 Modulates Gram-Positive Bacterial Internalization and Survival in Gingival Epithelial Cells

Authors: Manoj Reddy Medapati, Anjali Yadav Bhagirath, Nisha Singh, Robert J Schroth, Rajinder P Bhullar, Kangmin Duan, Prashen Chelikani

Journal: Int J Mol Sci

PubMed ID: 34576085

Doi: 10.3390/ijms22189920

Products & Services: Mammalian Expression

The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling

Authors: Chen Shen, Anmada Nayak, Leif R Neitzel, Amber A Adams, Maya Silver-Isenstadt, Leah M Sawyer, Hassina Benchabane, Huilan Wang, Nawat Bunnag, Bin Li, Daniel T Wynn, Fan Yang, Marta Garcia-Contreras, Charles H Williams, Sivanesan Dakshanamurthy, Charles C Hong, Nagi G Ayad, Anthony J Capobianco, Yashi Ahmed, Ethan Lee, David J Robbins

Journal: Nat Commun

PubMed ID: 34489457

Doi: 10.1038/s41467-021-25634-z

Products & Services: Mammalian Expression

ONAC066, A Stress-Responsive NAC Transcription Activator, Positively Contributes to Rice Immunity Against Through Modulating Expression of and Three Cytochrome P450 Genes

Authors: Xi Yuan, Hui Wang, Yan Bi, Yuqing Yan, Yizhou Gao, Xiaohui Xiong, Jiajing Wang, Dayong Li, Fengming Song

Journal: Front Plant Sci

PubMed ID: 34567053

Doi: 10.3389/fpls.2021.749186

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Trivalent Subunit Vaccine Candidates for COVID-19 and Their Delivery Devices

Authors: Oscar A Ortega-Rivera, Matthew D Shin, Angela Chen, Veronique Beiss, Miguel A Moreno-Gonzalez, Miguel A Lopez-Ramirez, Maria Reynoso, Hong Wang, Brett L Hurst, Joseph Wang, Jonathan K Pokorski, Nicole F Steinmetz

Journal: J Am Chem Soc

PubMed ID: 34490778

Doi: 10.1021/jacs.1c06600

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Rapid reconstruction of porcine reproductive and respiratory syndrome virus using synthetic DNA fragments

Authors: Julien Mélade, Géraldine Piorkowski, Hawa Sophia Bouzidi, Alain Medawar, Claudine Raffy, Xavier de Lamballerie, Antoine Nougairède

Journal: Comput Struct Biotechnol J

PubMed ID: 34589186

Doi: 10.1016/j.csbj.2021.08.040

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Shaping Liposomes by Cell-Free Expressed Bacterial Microtubules

Authors: Johannes Kattan, Anne Doerr, Marileen Dogterom, Christophe Danelon

Journal: ACS Synth Biol

PubMed ID: 34585918

Doi: 10.1021/acssynbio.1c00278

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EndoBind detects endogenous protein-protein interactions in real time

Authors: Anke Bill, Sheryll Espinola, Daniel Guthy, Jacob R Haling, Mylene Lanter, Min Lu, Anthony Marelli, Angelica Mendiola, Loren Miraglia, Brandon L Taylor, Leonardo Vargas, Anthony P Orth, Frederick J King

Journal: Commun Biol

PubMed ID: 34526658

Doi: 10.1038/s42003-021-02600-5

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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M inhibitors

Authors: Srinivas Chamakuri, Shuo Lu, Melek Nihan Ucisik, Kurt M Bohren, Ying-Chu Chen, Huang-Chi Du, John C Faver, Ravikumar Jimmidi, Feng Li, Jian-Yuan Li, Pranavanand Nyshadham, Stephen S Palmer, Jeroen Pollet, Xuan Qin, Shannon E Ronca, Banumathi Sankaran, Kiran L Sharma, Zhi Tan, Leroy Versteeg, Zhifeng Yu, Martin M Matzuk, Timothy Palzkill, Damian W Young

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34426525

Doi: 10.1073/pnas.2111172118

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Loading Effect of Chitosan Derivative Nanoparticles on Different Antigens and Their Immunomodulatory Activity on Dendritic Cells

Authors: Chaojie Xu, Ronge Xing, Song Liu, Yukun Qin, Kecheng Li, Huahua Yu, Pengcheng Li

Journal: Mar Drugs

PubMed ID: 34677435

Doi: 10.3390/md19100536

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Stable isotope tracing to assess tumor metabolism in vivo

Authors: Brandon Faubert, Alpaslan Tasdogan, Sean J Morrison, Thomas P Mathews, Ralph J DeBerardinis

Journal: Nat Protoc

PubMed ID: 34535790

Doi: 10.1038/s41596-021-00605-2

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Genomic investigation of a household SARS-CoV-2 disease cluster in Arizona involving a cat, dog, and pet owner

Authors: Hayley D Yaglom, Gavriella Hecht, Andrew Goedderz, Daniel Jasso-Selles, Jennifer L Ely, Irene Ruberto, Jolene R Bowers, David M Engelthaler, Heather Venkat

Journal: One Health

PubMed ID: 34604494

Doi: 10.1016/j.onehlt.2021.100333

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FGF21 ameliorates hepatic fibrosis by multiple mechanisms

Authors: Fanrui Meng, Mir Hassan Khoso, Kai Kang, Qi He, Yukai Cao, Xinghao Jiang, Wei Xiao, Deshan Li

Journal: Mol Biol Rep

PubMed ID: 34536190

Doi: 10.1007/s11033-021-06707-0

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Molecular and Enzymatic Characterization of Flavonoid 3'-Hydroxylase of ×

Authors: Julia Weissensteiner, Christian Molitor, Silvija Marinovic, Lisa Führer, Syed Waqas Hassan, Olly Sanny Hutabarat, Andreas Spornberger, Karl Stich, Johanna Hausjell, Oliver Spadiut, Christian Haselmair-Gosch, Heidi Halbwirth

Journal: Plants (Basel)

PubMed ID: 34579488

Doi: 10.3390/plants10091956

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Hinge influences in murine IgG binding to Cryptococcus neoformans capsule

Authors: Diane Sthefany Lima de Oliveira, Verenice Paredes, Adrielle Veloso Caixeta, Nicole Moreira Henriques, Maggie P Wear, Patrícia Albuquerque, Maria Sueli Soares Felipe, Arturo Casadevall, André Moraes Nicola

Journal: Immunology

PubMed ID: 34458991

Doi: 10.1111/imm.13411

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Monophosphoryl Lipid A and Poly I:C Combination Adjuvant Promoted Ovalbumin-Specific Cell Mediated Immunity in Mice Model

Authors: So Yeon Ahn, Chau Thuy Tien Le, Eun-Ju Ko

Journal: Biology (Basel)

PubMed ID: 34571785

Doi: 10.3390/biology10090908

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Marburg and Ebola Virus mRNA 3' Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing

Authors: Sudip Khadka, Caroline G Williams, Joyce Sweeney-Gibbons, Christopher F Basler

Journal: J Virol

PubMed ID: 34346762

Doi: 10.1128/JVI.00652-21

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Antibody-dependent cellular cytotoxicity response to SARS-CoV-2 in COVID-19 patients

Authors: Yuanling Yu, Meiyu Wang, Xiaoai Zhang, Shufen Li, Qingbin Lu, Haolong Zeng, Hongyan Hou, Hao Li, Mengyi Zhang, Fei Jiang, Jiajing Wu, Ruxia Ding, Zehua Zhou, Min Liu, Weixue Si, Tao Zhu, Hangwen Li, Jie Ma, Yuanyuan Gu, Guangbiao She, Xiaokun Li, Yulan Zhang, Ke Peng, Weijin Huang, Wei Liu, Youchun Wang

Journal: Signal Transduct Target Ther

PubMed ID: 34561414

Doi: 10.1038/s41392-021-00759-1

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Tissue-Resident-Memory CD8 T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes

Authors: Tao Peng, Khamsone Phasouk, Catherine N Sodroski, Sijie Sun, Yon Hwangbo, Erik D Layton, Lei Jin, Alexis Klock, Kurt Diem, Amalia S Magaret, Lichen Jing, Kerry Laing, Alvason Li, Meei-Li Huang, Max Mertens, Christine Johnston, Keith R Jerome, David M Koelle, Anna Wald, David M Knipe, Lawrence Corey, Jia Zhu

Journal: Front Immunol

PubMed ID: 34552595

Doi: 10.3389/fimmu.2021.735643

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Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin

Authors: Delia Susan-Resiga, Emmanuelle Girard, Rachid Essalmani, Anna Roubtsova, Jadwiga Marcinkiewicz, Rabeb M Derbali, Alexandra Evagelidis, Jae H Byun, Paul F Lebeau, Richard C Austin, Nabil G Seidah

Journal: J Biol Chem

PubMed ID: 34508778

Doi: 10.1016/j.jbc.2021.101177

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Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton

Authors: Katharina Vestre, Irene Persiconi, Marita Borg Distefano, Nadia Mensali, Noemi Antonella Guadagno, Marine Bretou, Sébastien Wälchli, Catharina Arnold-Schrauf, Oddmund Bakke, Marc Dalod, Ana-Maria Lennon-Dumenil, Cinzia Progida

Journal: J Cell Sci

PubMed ID: 34494097

Doi: 10.1242/jcs.259221

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Expression of Biofilm-Degrading Enzymes in Plants and Automated High-Throughput Activity Screening Using Experimental Biofilms

Authors: P Opdensteinen, S J Dietz, B B Gengenbach, J F Buyel

Journal: Front Bioeng Biotechnol

PubMed ID: 34621728

Doi: 10.3389/fbioe.2021.708150

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Lipopolysaccharide Is a 4-Aminoarabinose Donor to Exogenous Polyisoprenyl Phosphates through the Reverse Reaction of the Enzyme ArnT

Authors: Beth A Scarbrough, Colleen R Eade, Amanda J Reid, Tiffany C Williams, Jerry M Troutman

Journal: ACS Omega

PubMed ID: 34632229

Doi: 10.1021/acsomega.1c04036

Products & Services: Proteins, Expression, Isolation and Analysis

Novel Antimicrobial Peptides from a Cecropin-Like Region of Heteroscorpine-1 from Venom with Membrane Disruption Activity

Authors: Rima Erviana, Yutthakan Saengkun, Prapenpuksiri Rungsa, Nisachon Jangpromma, Patcharaporn Tippayawat, Sompong Klaynongsruang, Jureerut Daduang, Sakda Daduang

Journal: Molecules

PubMed ID: 34641415

Doi: 10.3390/molecules26195872

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Genome-wide identification, evolution, and transcript profiling of Aldehyde dehydrogenase superfamily in potato during development stages and stress conditions

Authors: Md Sifatul Islam, Md Soyib Hasan, Md Nazmul Hasan, Shamsul H Prodhan, Tahmina Islam, Ajit Ghosh

Journal: Sci Rep

PubMed ID: 34521910

Doi: 10.1038/s41598-021-97691-9

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Resistance of SARS-CoV-2 Delta variant to neutralization by BNT162b2-elicited antibodies in Asians

Authors: Bei Wang, Yun Shan Goh, Siew-Wai Fong, Barnaby Edward Young, Eve Zi Xian Ngoh, Jean-Marc Chavatte, Siti Nazihah Mohd Salleh, Nicholas Kim-Wah Yeo, Siti Naqiah Amrun, Pei Xiang Hor, Chiew Yee Loh, Chia Yin Lee, Yi-Hao Chan, Zi Wei Chang, Matthew Zirui Tay, Angeline Rouers, Anthony Torres-Ruesta, Guillaume Carissimo, Mun Kuen Soh, Raphael Tze Chuen Lee, Yani Xu, Surinder Pada, Raymond Tzer Pin Lin, Yee-Sin Leo, David C Lye, Sebastian Maurer-Stroh, Lisa F P Ng, Laurent Renia, Cheng-I Wang

Journal: Lancet Reg Health West Pac

PubMed ID: 34568853

Doi: 10.1016/j.lanwpc.2021.100276

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MicroRNA-140-5p represses chondrocyte pyroptosis and relieves cartilage injury in osteoarthritis by inhibiting cathepsin B/Nod-like receptor protein 3

Authors: Lei Zhang, Jianjun Qiu, Jixiang Shi, Shaoyang Liu, Hanlin Zou

Journal: Bioengineered

PubMed ID: 34565303

Doi: 10.1080/21655979.2021.1985342

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Ultrafast, sensitive, and portable detection of COVID-19 IgG using flexible organic electrochemical transistors

Authors: Hong Liu, Anneng Yang, Jiajun Song, Naixiang Wang, Puiyiu Lam, Yuenling Li, Helen Ka-Wai Law, Feng Yan

Journal: Sci Adv

PubMed ID: 34524851

Doi: 10.1126/sciadv.abg8387

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Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys

Authors: Julien Baruteau, Sharon C Cunningham, Berna Seker Yilmaz, Dany P Perocheau, Simon Eaglestone, Derek Burke, Adrian J Thrasher, Simon N Waddington, Leszek Lisowski, Ian E Alexander, Paul Gissen

Journal: Mol Ther Methods Clin Dev

PubMed ID: 34703837

Doi: 10.1016/j.omtm.2021.09.005

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An observational study of breakthrough SARS-CoV-2 Delta variant infections among vaccinated healthcare workers in Vietnam

Authors: Nguyen Van Vinh Chau, Nghiem My Ngoc, Lam Anh Nguyet, Vo Minh Quang, Nguyen Thi Han Ny, Dao Bach Khoa, Nguyen Thanh Phong, Le Mau Toan, Nguyen Thi Thu Hong, Nguyen Thi Kim Tuyen, Voong Vinh Phat, Le Nguyen Truc Nhu, Nguyen Huynh Thanh Truc, Bui Thi Ton That, Huynh Phuong Thao, Tran Nguyen Phuong Thao, Vo Trong Vuong, Tran Thi Thanh Tam, Ngo Tan Tai, Ho The Bao, Huynh Thi Kim Nhung, Nguyen Thi Ngoc Minh, Nguyen Thi My Tien, Nguy Cam Huy, Marc Choisy, Dinh Nguyen Huy Man, Dinh Thi Bich Ty, Nguyen To Anh, Le Thi Tam Uyen, Tran Nguyen Hoang Tu, Lam Minh Yen, Nguyen Thanh Dung, Le Manh Hung, Nguyen Thanh Truong, Tran Tan Thanh, Guy Thwaites, Le Van Tan

Journal: EClinicalMedicine

PubMed ID: 34608454

Doi: 10.1016/j.eclinm.2021.101143

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Loss of Function of and in Rice Promotes Early Maturing and Semi-Dwarfism in γ-Irradiated IWP and Genome-Edited Pusa Basmati-1

Authors: M T Andrew-Peter-Leon, Ramchander Selvaraj, K K Kumar, Mehanathan Muthamilarasan, Jeshima Khan Yasin, M Arumugam Pillai

Journal: Front Plant Sci

PubMed ID: 34630462

Doi: 10.3389/fpls.2021.714066

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Plant-Expressed Receptor Binding Domain of the SARS-CoV-2 Spike Protein Elicits Humoral Immunity in Mice

Authors: Puna Maya Maharjan, Jinyeong Cheon, Jiyun Jung, Haerim Kim, Jaewon Lee, Minjeong Song, Gi Uk Jeong, Youngchan Kwon, Byoungshik Shim, Sunghwa Choe

Journal: Vaccines (Basel)

PubMed ID: 34579215

Doi: 10.3390/vaccines9090978

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Virus-specific T cells for adenovirus infection after stem cell transplantation are highly effective and class II HLA restricted

Authors: Jeremy D Rubinstein, Xiang Zhu, Thomas Leemhuis, Giang Pham, Lorraine Ray, Sana Emberesh, Sonata Jodele, Shawn Thomas, Jose A Cancelas, Catherine M Bollard, Patrick J Hanley, Michael D Keller, Olivia Grimley, Diana Clark, Teri Clark, Cecilia S Lindestam Arlehamn, Alessandro Sette, Stella M Davies, Adam S Nelson, Michael S Grimley, Carolyn Lutzko

Journal: Blood Adv

PubMed ID: 34473237

Doi: 10.1182/bloodadvances.2021004456

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Glycosylation reduces the glycan-independent immunomodulatory effect of recombinant Orysata lectin in Drosophila S2 cells

Authors: Pengyu Chen, Kristof De Schutter, Sonia Serna, Simin Chen, Qun Yang, Niels-Christian Reichardt, Els J M Van Damme, Guy Smagghe

Journal: Sci Rep

PubMed ID: 34504130

Doi: 10.1038/s41598-021-97161-2

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Circular RNA hsa_circ_0001598 promotes programmed death-ligand-1-mediated immune escape and trastuzumab resistance via sponging miR-1184 in breast cancer cells

Authors: Li Huang, Jing Ma, Min Cui

Journal: Immunol Res

PubMed ID: 34559381

Doi: 10.1007/s12026-021-09237-w

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A Peptide-Based Assay Discriminates Individual Antibody Response to the COVID-19 Pfizer/BioNTech mRNA Vaccine

Authors: Immacolata Polvere, Serena Voccola, Alfredina Parrella, Gaetano Cardinale, Lucrezia Zerillo, Romualdo Varricchio, Jessica Raffaella Madera, Romania Stilo, Pasquale Vito, Tiziana Zotti

Journal: Vaccines (Basel)

PubMed ID: 34579224

Doi: 10.3390/vaccines9090987

Prior infection and age impacts antibody persistence after SARS-CoV-2 mRNA vaccine

Authors: Elizabeth Fraley, Cas LeMaster, Santosh Khanal, Dithi Banerjee, Tomi Pastinen, Elin Grundberg, Rangaraj Selvarangan, Todd Bradley

Journal: Clin Infect Dis

PubMed ID: 34551091

Doi: 10.1093/cid/ciab850

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Prior infection and age impacts antibody persistence after SARS-CoV-2 mRNA vaccine

Authors: Elizabeth Fraley, Cas LeMaster, Santosh Khanal, Dithi Banerjee, Tomi Pastinen, Elin Grundberg, Rangaraj Selvarangan, Todd Bradley

Journal: Clin Infect Dis

PubMed ID: 34551091

Doi: 10.1093/cid/ciab850

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The PshX subunit of the photochemical reaction center from Heliobacterium modesticaldum acts as a low-energy antenna

Authors: Gregory S Orf, Christopher J Gisriel, Jesse Granstrom, Patricia L Baker, Kevin E Redding

Journal: Photosynth Res

PubMed ID: 34480322

Doi: 10.1007/s11120-021-00871-x

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Cytochrome P450-catalyzed biosynthesis of furanoditerpenoids in the bioenergy crop switchgrass (Panicum virgatum L)

Authors: Andrew Muchlinski, Meirong Jia, Kira Tiedge, Jason S Fell, Kyle A Pelot, Lisl Chew, Danielle Davisson, Yuxuan Chen, Justin Siegel, John T Lovell, Philipp Zerbe

Journal: Plant J

PubMed ID: 34514645

Doi: 10.1111/tpj.15492

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Recombinant expression, purification, and characterization of full-length human BST-2 from Escherichia coli

Authors: Amukelani Marivate, Zikhona Njengele-Tetyana, Muhammad Qasim Fish, Salerwe Mosebi

Journal: Protein Expr Purif

PubMed ID: 34500069

Doi: 10.1016/j.pep.2021.105969

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Multiplexed analysis of small extracellular vesicle-derived mRNAs by droplet digital PCR and machine learning improves breast cancer diagnosis

Authors: Chunchen Liu, Bo Li, Huixian Lin, Chao Yang, Jingyun Guo, Binbin Cui, Weilun Pan, Junjie Feng, Tingting Luo, Fuxin Chu, Xiaonan Xu, Lei Zheng, Shuhuai Yao

Journal: Biosens Bioelectron

PubMed ID: 34507095

Doi: 10.1016/j.bios.2021.113615

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, Encoding a Pentatricopeptide Repeat Protein, Is Essential for Chloroplast RNA Editing and Biogenesis in Soybean

Authors: Xingxing Feng, Suxin Yang, Yaohua Zhang, Cheng Zhiyuan, Kuanqiang Tang, Guang Li, Hui Yu, Jiantian Leng, Qingyu Wang

Journal: Front Plant Sci

PubMed ID: 34567023

Doi: 10.3389/fpls.2021.690973

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PCV2 targets cGAS to inhibit type I interferon induction to promote other DNA virus infection

Authors: Zhenyu Wang, Jing Chen, Xingchen Wu, Dan Ma, Xiaohua Zhang, Ruizhen Li, Cong Han, Haixin Liu, Xiangrui Yin, Qian Du, Dewen Tong, Yong Huang