客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 81/514 每页显示数量

Insulin-like growth factor 2 mRNA binding protein 2 regulates proliferation, migration and angiogenesis of keratinocytes by modulating heparanase stability

Authors: Shaomin Zhi, Jun Li, Xiao Kong, Xuemei Xie, Qiangli Zhang, Guoxiang Fang

Journal: Bioengineered

PubMed ID: 34753397

Doi: 10.1080/21655979.2021.2002495

Products & Services: ORF cDNA Clones/MolecularCloud

Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes

Authors: Pim J Huis In 't Veld, Sabine Wohlgemuth, Carolin Koerner, Franziska Müller, Petra Janning, Andrea Musacchio

Journal: Protein Sci

PubMed ID: 34791727

Doi: 10.1002/pro.4233

Products & Services: Proteins, Expression, Isolation and Analysis

His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation

Authors: Gabrielle Parkinson, Peristera Roboti, Ling Zhang, Sandra Taylor, Philip Woodman

Journal: J Cell Sci

PubMed ID: 34657963

Doi: 10.1242/jcs.259192

Products & Services: Catalog Antibody

SARS-CoV-2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets

Authors: Syam Prakash Somasekharan, Martin Gleave

Journal: FEBS Lett

PubMed ID: 34780058

Doi: 10.1002/1873-3468.14229

Products & Services: Catalog Antibody

Serine palmitoyltransferase assembles at ER-mitochondria contact sites

Authors: Mari J Aaltonen, Irina Alecu, Tim König, Steffany Al Bennett, Eric A Shoubridge

Journal: Life Sci Alliance

PubMed ID: 34785538

Doi: 10.26508/lsa.202101278

Products & Services: Catalog Antibody

Limited Impact of Delta Variant's Mutations on the Effectiveness of Neutralization Conferred by Natural Infection or COVID-19 Vaccines in a Latino Population

Authors: Carlos A Sariol, Crisanta Serrano-Collazo, Edwin J Ortiz, Petraleigh Pantoja, Lorna Cruz, Teresa Arana, Dianne Atehortua, Christina Pabon-Carrero, Ana M Espino

Journal: Viruses

PubMed ID: 34960674

Doi: 10.3390/v13122405

Products & Services: Catalog Antibody

Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages

Authors: Christian Kretzer, Paul M Jordan, Katharina P L Meyer, Daniel Hoff, Markus Werner, Robert Klaus Hofstetter, Andreas Koeberle, Antonio Cala Peralta, Guillaume Viault, Denis Seraphin, Pascal Richomme, Jean-Jacques Helesbeux, Hermann Stuppner, Veronika Temml, Daniela Schuster, Oliver Werz

Journal: Biochem Pharmacol

PubMed ID: 34762841

Doi: 10.1016/j.bcp.2021.114825

Products & Services: Catalog Peptides

Unveiling mRNP composition by fluorescence correlation and cross-correlation spectroscopy using cell lysates

Authors: Àngels Mateu-Regué, Jan Christiansen, Frederik Otzen Bagger, Christian Hellriegel, Finn Cilius Nielsen

Journal: Nucleic Acids Res

PubMed ID: 34478550

Doi: 10.1093/nar/gkab751

Products & Services: Mutagenesis Services

Immune reactivity and host modulatory roles of two novel Haemonchus contortus cathepsin B-like proteases

Authors: Mariam Bakshi, Wenbin Tuo, Raffi V Aroian, Dante Zarlenga

Journal: Parasit Vectors

PubMed ID: 34798906

Doi: 10.1186/s13071-021-05010-y

Products & Services: Proteins, Expression, Isolation and Analysis

Piwi4 Structural Features Are Necessary for RNA Binding and Nuclear Localization

Authors: Adeline E Williams, Gaurav Shrivastava, Apostolos G Gittis, Sundar Ganesan, Ines Martin-Martin, Paola Carolina Valenzuela Leon, Ken E Olson, Eric Calvo

Journal: Int J Mol Sci

PubMed ID: 34884537

Doi: 10.3390/ijms222312733

Products & Services: Proteins, Expression, Isolation and Analysis

Gain of Spontaneous Mutations Boosting Motility Adaption to Environments in

Authors: Bingyu Li, Chaofan Hou, Xian Ju, Yong Feng, Zhi-Qiang Ye, Yunzhu Xiao, Mingyao Gu, Chunxiang Fu, Chaoliang Wei, Conghui You

Journal: Front Bioeng Biotechnol

PubMed ID: 34900963

Doi: 10.3389/fbioe.2021.772397

Products & Services: Catalog Antibody

G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators

Authors: Malarvizhi Gurusamy, Denise Tischner, Jingchen Shao, Stephan Klatt, Sven Zukunft, Remy Bonnavion, Stefan Günther, Kai Siebenbrodt, Roxane-Isabelle Kestner, Tanja Kuhlmann, Ingrid Fleming, Stefan Offermanns, Nina Wettschureck

Journal: Nat Commun

PubMed ID: 34815397

Doi: 10.1038/s41467-021-26882-9

Products & Services: Custom DNA/RNA Oligos

Curcumol inhibits malignant biological behaviors and TMZ-resistance in glioma cells by inhibiting long noncoding RNA FOXD2-As1-promoted EZH2 activation

Authors: Xuyang Lv, Jiangchuan Sun, Linfeng Hu, Ying Qian, Chunlei Fan, Nan Tian

Journal: Aging (Albany NY)

PubMed ID: 34739394

Doi: 10.18632/aging.203662

Products & Services: Custom DNA/RNA Oligos

Nogo receptor impairs the clearance of fibril amyloid-β by microglia and accelerates Alzheimer's-like disease progression

Authors: Jianing Wang, Xiaoying Qin, Hao Sun, Meijun He, Qunyu Lv, Congcong Gao, Xinran He, Hong Liao

Journal: Aging Cell

PubMed ID: 34821024

Doi: 10.1111/acel.13515

Products & Services: Custom DNA/RNA Oligos

Plant LHC-like proteins show robust folding and static non-photochemical quenching

Authors: Petra Skotnicová, Hristina Staleva-Musto, Valentyna Kuznetsova, David Bína, Minna M Konert, Shan Lu, Tomáš Polívka, Roman Sobotka

Journal: Nat Commun

PubMed ID: 34824207

Doi: 10.1038/s41467-021-27155-1

Products & Services: Gene Synthesis

Spike residue 403 affects binding of coronavirus spikes to human ACE2

Authors: Fabian Zech, Daniel Schniertshauer, Christoph Jung, Alexandra Herrmann, Arne Cordsmeier, Qinya Xie, Rayhane Nchioua, Caterina Prelli Bozzo, Meta Volcic, Lennart Koepke, Janis A Müller, Jana Krüger, Sandra Heller, Steffen Stenger, Markus Hoffmann, Stefan Pöhlmann, Alexander Kleger, Timo Jacob, Karl-Klaus Conzelmann, Armin Ensser, Konstantin M J Sparrer, Frank Kirchhoff

Journal: Nat Commun

PubMed ID: 34824253

Doi: 10.1038/s41467-021-27180-0

Products & Services: Catalog Antibody

SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II

Authors: Richard King, Zesen Lin, Ginette Balbin-Cuesta, Gregg Myers, Ann Friedman, Guojing Zhu, Beth McGee, Thomas L Saunders, Ryo Kurita, Yukio Nakamura, James Douglas Engel, Pavan Reddy, Rami Khoriaty

Journal: Sci Adv

PubMed ID: 34818036

Doi: 10.1126/sciadv.abj5293

Products & Services: Codon Optimization

PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ

Authors: Fengxiang Wang, Emily T Graham, Nathchar Naowarojna, Zhennan Shi, Yuqi Wang, Guanglei Xie, Lili Zhou, Wendy Salmon, Jie-Min Jia, Xi Wang, Yuwei Huang, Stuart L Schreiber, Yilong Zou

Journal: Cell Chem Biol

PubMed ID: 34813762

Doi: 10.1016/j.chembiol.2021.11.001

Products & Services: Proteins, Expression, Isolation and Analysis

Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats

Authors: Xuankang Wang, Xin Li, Xiaoshuang Zuo, Zhuowen Liang, Tan Ding, Kun Li, Yangguang Ma, Penghui Li, Zhijie Zhu, Cheng Ju, Zhihao Zhang, Zhiwen Song, Huilin Quan, Jiawei Zhang, Xueyu Hu, Zhe Wang

Journal: J Neuroinflammation

PubMed ID: 34740378

Doi: 10.1186/s12974-021-02312-x

Products & Services: Proteins, Expression, Isolation and Analysis

3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels

Authors: Niraimathi Govindasamy, Hongyan Long, Hyun-Woo Jeong, Ratish Raman, Burak Özcifci, Simone Probst, Sebastian J Arnold, Kristina Riehemann, Adrian Ranga, Ralf H Adams, Britta Trappmann, Ivan Bedzhov

Journal: Dev Cell

PubMed ID: 34741805

Doi: 10.1016/j.devcel.2021.10.014

Products & Services: Proteins, Expression, Isolation and Analysis

Capillary electrophoresis-based functional genomics screening to discover novel archaeal DNA modifying enzymes

Authors: Kelly M Zatopek, Samantha L Fossa, Katharina Bilotti, Paul J Caffrey, Léa Chuzel, Alexandra M Gehring, Gregory J S Lohman, Christopher H Taron, Andrew F Gardner

Journal: Appl Environ Microbiol

PubMed ID: 34788065

Doi: 10.1128/AEM.02137-21

Products & Services: Plasmid DNA Preparation

New highly antigenic linear B cell epitope peptides from PvAMA-1 as potential vaccine candidates

Authors: Raianna F Fantin, Vanessa G Fraga, Camila A Lopes, Isabella C de Azevedo, João L Reis-Cunha, Dhelio B Pereira, Francisco P Lobo, Marcela M de Oliveira, Anderson C Dos Santos, Daniela C Bartholomeu, Ricardo T Fujiwara, Lilian L Bueno

Journal: PLoS ONE

PubMed ID: 34727117

Doi: 10.1371/journal.pone.0258637

Products & Services: Plasmid DNA Preparation

The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1

Authors: Beatriz Sanchez-Solana, Dunrui Wang, Xiaolan Qian, Parthibane Velayoudame, Dhirendra K Simanshu, Jairaj K Acharya, Douglas R Lowy

Journal: Mol Cancer

PubMed ID: 34727930

Doi: 10.1186/s12943-021-01439-y

Products & Services: PCR Cloning and Subcloning

The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses

Authors: David M Picton, Yvette A Luyten, Richard D Morgan, Andrew Nelson, Darren L Smith, David T F Dryden, Jay C D Hinton, Tim R Blower

Journal: Nucleic Acids Res

PubMed ID: 34657954

Doi: 10.1093/nar/gkab906

Products & Services: Mutant Libraries

Effector-mediated membrane disruption controls cell death in CBASS antiphage defense

Authors: Brianna Duncan-Lowey, Nora K McNamara-Bordewick, Nitzan Tal, Rotem Sorek, Philip J Kranzusch

Journal: Mol Cell

PubMed ID: 34784509

Doi: 10.1016/j.molcel.2021.10.020

Products & Services: Mutant Libraries

Stress Induced Transcription Factors Transactivate the Herpes Simplex Virus 1 Infected Cell Protein 27 (ICP27) Transcriptional Enhancer

Authors: Jeffery B Ostler, Clinton Jones

Journal: Viruses

PubMed ID: 34835102

Doi: 10.3390/v13112296

Products & Services: Mutant Libraries

A mosquito AgTRIO monoclonal antibody reduces early infection of mice

Authors: Yu-Min Chuang, Xu-Dong Tang, Erol Fikrig

Journal: Infect Immun

PubMed ID: 34724388

Doi: 10.1128/IAI.00359-21

Products & Services: Insect Expression Monoclonal Antibody Services Peptide Synthesis

Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization

Authors: Nikolas Friedrich, Emanuel Stiegeler, Matthias Glögl, Thomas Lemmin, Simon Hansen, Claus Kadelka, Yufan Wu, Patrick Ernst, Liridona Maliqi, Caio Foulkes, Mylène Morin, Mustafa Eroglu, Thomas Liechti, Branislav Ivan, Thomas Reinberg, Jonas V Schaefer, Umut Karakus, Stephan Ursprung, Axel Mann, Peter Rusert, Roger D Kouyos, John A Robinson, Huldrych F Günthard, Andreas Plückthun, Alexandra Trkola

Journal: Nat Commun

PubMed ID: 34795280

Doi: 10.1038/s41467-021-27075-0

Products & Services: GenParts™ DNA Fragments

Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation

Authors: Hengjun Cui, Andreas U Müller, Marc Leibundgut, Jiawen Tian, Nenad Ban, Eilika Weber-Ban

Journal: Nat Commun

PubMed ID: 34789727

Doi: 10.1038/s41467-021-26848-x

Products & Services: GenParts™ DNA Fragments

Tryptophan Side-Chain Oxidase Enzyme Suppresses Hepatocellular Carcinoma Growth through Degradation of Tryptophan

Authors: Yang Ai, Ben Wang, Shuai Xiao, Sang Luo, Yefu Wang

Journal: Int J Mol Sci

PubMed ID: 34830310

Doi: 10.3390/ijms222212428

Products & Services: Endotoxin Detection & Removal System

Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination

Authors: Wooseob Kim, Julian Q Zhou, Alexandria J Sturtz, Stephen C Horvath, Aaron J Schmitz, Tingting Lei, Elizaveta Kalaidina, Mahima Thapa, Wafaa B Alsoussi, Alem Haile, Michael K Klebert, Teresa Suessen, Luis Parra-Rodriguez, Philip A Mudd, William D Middleton, Sharlene A Teefey, Iskra Pusic, Jane A O'Halloran, Rachel M Presti, Jackson S Turner, Ali H Ellebedy

Journal: biorxiv

PubMed ID: 34751268

Doi: 10.1101/2021.10.31.466651

Products & Services: Custom Vector Construction

MiR-702-3p inhibits the inflammatory injury in septic H9c2 cells by regulating NOD1

Authors: Chun Liu, Yang Yang, Guiwen Liang, Aixian Zhang, Feng Xu

Journal: Transpl Immunol

PubMed ID: 34774740

Doi: 10.1016/j.trim.2021.101493

Products & Services: Custom Vector Construction

T cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas

Authors: Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O Breckwoldt, Gerald Willimksy, Stefan B Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, Lukas Bunse

Journal: Clin Cancer Res

PubMed ID: 34782365

Doi: 10.1158/1078-0432.CCR-21-1881

Products & Services: Custom DNA/RNA Oligos

Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus

Authors: Ebru Destan, Busra Yuksel, Bradley B Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A Francis, Hasan DeMirci

Journal: Sci Rep

PubMed ID: 34819551

Doi: 10.1038/s41598-021-02180-8

Products & Services: Codon Optimization

Proteolytic processing of plant proteins by potyvirus NIa proteases

Authors: Huogen Xiao, Etienne Lord, Hélène Sanfaçon

Journal: J Virol

PubMed ID: 34757836

Doi: 10.1128/JVI.01444-21

Products & Services: Codon Optimization

Structure of native HIV-1 cores and their interactions with IP6 and CypA

Authors: Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till Böcking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang

Journal: Sci Adv

PubMed ID: 34797722

Doi: 10.1126/sciadv.abj5715

Products & Services: Codon Optimization

Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity

Authors: Jonathan P Renn, Justin Y A Doritchamou, Bergeline C Nguemwo Tentokam, Robert D Morrison, Matthew V Cowles, Martin Burkhardt, Rui Ma, Niraj H Tolia, Michal Fried, Patrick E Duffy

Journal: Commun Biol

PubMed ID: 34799664

Doi: 10.1038/s42003-021-02787-7

Products & Services: Codon Optimization

Multi-Antigen Outer Membrane Vesicle Engineering to Develop Polyvalent Vaccines: The Case

Authors: Enrico König, Assunta Gagliardi, Ilary Riedmiller, Chiara Andretta, Michele Tomasi, Carmela Irene, Luca Frattini, Ilaria Zanella, Francesco Berti, Alberto Grandi, Elena Caproni, Laura Fantappiè, Guido Grandi

Journal: Front Immunol

PubMed ID: 34819933

Doi: 10.3389/fimmu.2021.752168

Products & Services: Catalog Peptides

Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy

Authors: Jun Zheng, Xi Chen, Qiang Liu, Guisheng Zhong, Min Zhuang

Journal: J Cell Biol

PubMed ID: 34747980

Doi: 10.1083/jcb.202103156

Products & Services: Catalog Antibody

Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice

Authors: Cherng-Shyang Chang, Yi-Chu Liao, Chih-Ting Huang, Chiao-Mei Lin, Chantal Hoi Yin Cheung, Jhen-Wei Ruan, Wen-Hsuan Yu, Yi-Ting Tsai, I-Jung Lin, Chien-Hsun Huang, Jong-Shian Liou, Ya-Hsien Chou, Hung-Jen Chien, Hsiao-Li Chuang, Hsueh-Fen Juan, Hsuan-Cheng Huang, Hong-Lin Chan, Yu-Chieh Liao, Shiue-Cheng Tang, Yu-Wen Su, Tse-Hua Tan, Andreas J Bäumler, Cheng-Yuan Kao

Journal: Cell Rep

PubMed ID: 34818535

Doi: 10.1016/j.celrep.2021.110016

Products & Services: Recombinant Proteins

Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains*

Authors: Karen T Elvers, Magdalena Lipka-Lloyd, Rebecca C Trueman, Benjamin D Bax, Youcef Mehellou

Journal: Chembiochem

PubMed ID: 34726826

Doi: 10.1002/cbic.202100441

Products & Services: Gene Synthesis

Pharmacological modulation of the cAMP signaling of two isoforms of melanocortin-3 receptor by melanocortin receptor accessory proteins in the tetrapod Xenopus laevis

Authors: Ying Xu, Lei Li, Jihong Zheng, Meng Wang, Bopei Jiang, Yue Zhai, Liumei Lu, Cong Zhang, Zhe Kuang, Xiaomei Yang, Li-Na Jin, Gufa Lin, Chao Zhang

Journal: Endocr Connect

PubMed ID: 34678757

Doi: 10.1530/EC-21-0179

Products & Services: Recombinant Proteins

Structure of Rift Valley fever virus RNA-dependent RNA polymerase

Authors: Xue Wang, Cuixia Hu, Wei Ye, Jia Wang, Xiaofei Dong, Jie Xu, Xiaorong Li, Manfeng Zhang, Hongyun Lu, Fanglin Zhang, Wei Wu, Shaodong Dai, Hong-Wei Wang, Zhongzhou Chen

Journal: J Virol

PubMed ID: 34787453

Doi: 10.1128/JVI.01713-21

Products & Services: Proteins, Expression, Isolation and Analysis

Alpha adaptins show isoform-specific association with neurofibrillary tangles in Alzheimer's disease

Authors: Sukanya Srinivasan, Jozsef Gal, Adam Bachstetter, Peter T Nelson

Journal: Neuropathol Appl Neurobiol

PubMed ID: 34820873

Doi: 10.1111/nan.12776

Products & Services: Catalog Antibody

ABCC2 is a functional receptor of Bacillus thuringiensis Cry1Ca in Spodoptera litura

Authors: Xue Yao, Chen Liu, Yunpeng Duan, Shiheng An, Jizhen Wei, Gemei Liang

Journal: Int J Biol Macromol

PubMed ID: 34861271

Doi: 10.1016/j.ijbiomac.2021.11.174

Products & Services: Recombinant Proteins

Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides

Authors: Maria Carmina Scala, Simone Di Micco, Delia Lanzillotta, Simona Musella, Veronica Di Sarno, Barbara Parrino, Stella Maria Casciofierro, Giuseppe Bifulco, Francesco Trapasso, Pietro Campiglia, Marina Sala

Journal: Front Mol Biosci

PubMed ID: 34901149

Doi: 10.3389/fmolb.2021.715263

Products & Services: Recombinant Proteins

Molecular characterization of substrate-induced ubiquitin transfer by UBR7-PHD finger, a newly identified histone H2BK120 ubiquitin ligase

Authors: Anirban Dasgupta, Payel Mondal, Sambit Dalui, Chandrima Das, Siddhartha Roy

Journal: FEBS J

PubMed ID: 34739193

Doi: 10.1111/febs.16262

Products & Services: Recombinant Proteins

Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds

Authors: Eline van Diest, Patricia Hernández López, Angelo D Meringa, Anna Vyborova, Froso Karaiskaki, Sabine Heijhuurs, Jan Gumathi Bormin, Sanne van Dooremalen, Mara J T Nicolasen, Lucrezia C D E Gatti, Inez Johanna, Trudy Straetemans, Zsolt Sebestyén, Dennis X Beringer, Jürgen Kuball

Journal: J Immunother Cancer

PubMed ID: 34815357

Doi: 10.1136/jitc-2021-003850

Products & Services: Peptide Synthesis

The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid

Authors: Anton A Stepnov, Idd A Christensen, Zarah Forsberg, Finn L Aachmann, Gaston Courtade, Vincent G H Eijsink

Journal: FEBS Lett

PubMed ID: 34845720

Doi: 10.1002/1873-3468.14246

Products & Services: Gene Synthesis

Structural characterization of the porcine adeno-associated virus Po1 capsid protein binding to the nuclear trafficking protein importin alpha

Authors: Mikayla Hoad, Justin A Roby, Jade K Forwood

Journal: FEBS Lett

PubMed ID: 34661283

Doi: 10.1002/1873-3468.14209

Products & Services: Bacterial Expression

A simple PCR-RFLP method for identification and detection of medicinal toad and its crude drug even with serious degradation of DNA

Authors: Jiao Liu, Xinyi Shao, Ziying Zhou, Miao Lei, Mingyu Xia, Dong Wang

Journal: J Pharm Biomed Anal

PubMed ID: 34864355

Doi: 10.1016/j.jpba.2021.114495

Products & Services: Custom DNA/RNA Oligos

1,800 MHz Radiofrequency Electromagnetic Irradiation Impairs Neurite Outgrowth With a Decrease in Rap1-GTP in Primary Mouse Hippocampal Neurons and Neuro2a Cells

Authors: Yanqi Li, Ping Deng, Chunhai Chen, Qinlong Ma, Huifeng Pi, Mindi He, Yonghui Lu, Peng Gao, Chao Zhou, Zhixin He, Yanwen Zhang, Zhengping Yu, Lei Zhang

Journal: Front Public Health

PubMed ID: 34881219

Doi: 10.3389/fpubh.2021.771508

Products & Services: Gene Synthesis

Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy

Authors: Cristina Gil-Cruz, Christian Perez-Shibayama, Angelina De Martin, Francesca Ronchi, Katrien van der Borght, Rebekka Niederer, Lucas Onder, Mechthild Lütge, Mario Novkovic, Veronika Nindl, Gustavo Ramos, Markus Arnoldini, Emma M C Slack, Valérie Boivin-Jahns, Roland Jahns, Madeleine Wyss, Catherine Mooser, Bart N Lambrecht, Micha T Maeder, Hans Rickli, Lukas Flatz, Urs Eriksson, Markus B Geuking, Kathy D McCoy, Burkhard Ludewig

Journal: Science

PubMed ID: 31727837

Doi: 10.1126/science.aav3487

Products & Services: Peptoid Synthesis Peptide Library Services

Two energy barriers and a transient intermediate state determine the unfolding and folding dynamics of cold shock protein

Authors: Haiyan Hong, Zilong Guo, Hao Sun , Ping Yu , Huanhuan Su , Xuening Ma & Hu Chen

Journal: Communications Chemistry

Doi: doi.org/10.1038/s42004-021-00592-1

Products & Services: Gene Synthesis

Performance Evaluation of the BZ COVID-19 Neutralizing Antibody Test for the Culture-Free and Rapid Detection of SARS-CoV-2 Neutralizing Antibodies

Authors: Bo Kyeung Jung, Jung Yoon, Joon-Yong Bae, Jeonghun Kim, Man-Seong Park, Suk Yong Lee, Chae Seung Lim

Journal: Diagnostics (Basel)

PubMed ID: 34943430

Doi: 10.3390/diagnostics11122193

Products & Services: Protein Reagents and Products

Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein

Authors: Hristo L Svilenov, Julia Sacherl, Alwin Reiter, Lisa S Wolff, Cho-Chin Cheng, Marcel Stern, Vincent Grass, Martin Feuerherd, Frank-Peter Wachs, Nicole Simonavicius, Susanne Pippig, Florian Wolschin, Oliver T Keppler, Johannes Buchner, Carsten Brockmeyer, Ulrike Protzer

Journal: Antiviral Res

PubMed ID: 34774603

Doi: 10.1016/j.antiviral.2021.105197

Products & Services: Protein Reagents and Products

Kinetics of anti-SARS-CoV-2 neutralizing antibodies development after BNT162b2 vaccination in patients with amyloidosis and the impact of therapy

Authors: Efstathios Kastritis, Evangelos Terpos, Zoi Evangelakou, Foteini Theodorakakou, Despina Fotiou, Maria S Manola, Despoina D Gianniou, Tina Bagratuni, Nikolaos Kanellias, Magdalini Migkou, Maria Gavriatopoulou, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Am J Hematol

PubMed ID: 34778995

Doi: 10.1002/ajh.26406

Products & Services: Catalog Antibody

Backbone H, N, and C resonance assignments of the non-structural protein NS2B of Zika virus

Authors: Beatriz Rosa Penna, Danielle Maria P de Oliveira, Cristiane Dinis Anobom, Ana Paula Valente

Journal: Biomol NMR Assign

PubMed ID: 34817802

Doi: 10.1007/s12104-021-10055-2

Products & Services: Codon Optimization

JNK/Itch Axis Mediates the Lipopolysaccharide-Induced Ubiquitin-Proteasome-Dependent Degradation of Ferritin Light Chain in Murine Macrophage Cells

Authors: Shufen He, Jianqi Xue, Pengxiu Cao, Jianyuan Hou, Yan Cui, Jing Chang, Liying Huang, Yu Han, Xianglin Duan, Ke Tan, Yumei Fan

Journal: Inflammation

PubMed ID: 34837126

Doi: 10.1007/s10753-021-01603-y

Products & Services: Custom Vector Construction

The concentration of brain homogenates with the Amicon Ultra Centrifugal filters

Authors: Joshua Yang, Rachita K Sumbria

Journal: MethodsX

PubMed ID: 35004217

Doi: 10.1016/j.mex.2021.101584

Products & Services: Catalog Antibody

Characterization of Anti-Ana o 3 Monoclonal Antibodies and Their Application in Comparing Brazilian Cashew Cultivars

Authors: Christopher P Mattison, Barry Vant-Hull, Ana Cecilia Ribeiro de Castro, Heidi J Chial, Yvette Bren-Mattison, Peter J Bechtel, Edy Sousa de Brito

Journal: Antibodies (Basel)

PubMed ID: 34939998

Doi: 10.3390/antib10040046

Products & Services: DNA Sequencing

Endotoxin contamination in commercially available Cas9 proteins potentially induces T-cell mediated responses

Authors: Vijaya L Simhadri, Joseph R McGill, Zuben E Sauna

Journal: Gene Ther

PubMed ID: 34744169

Doi: 10.1038/s41434-021-00301-6

Products & Services: Proteins, Expression, Isolation and Analysis

Cholecystokinin-B Receptor-Targeted Nanoparticle for Imaging and Detection of Precancerous Lesions in the Pancreas

Authors: Jill P Smith, Hong Cao, Elijah F Edmondson, Siva Sai Krishna Dasa, Stephan T Stern

Journal: Biomolecules

PubMed ID: 34944412

Doi: 10.3390/biom11121766

Products & Services: Catalog Peptides

Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus

Authors: Mintu Chandra, Brett M Collins, Lauren P Jackson

Journal: Adv Biol Regul

PubMed ID: 34866035

Doi: 10.1016/j.jbior.2021.100842

Products & Services: Catalog Peptides

Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy

Authors: Sheng-Li Ming , Shuang Zhang , Qi Wang , Lei Zeng , Lu-Yu Zhou , Meng-Di Wang , Ying-Xian Ma , Li-Qiang Han , Kai Zhong , He-Shui Zhu , Yi-Lin Bai , Guo-Yu Yang , Jiang Wang , Bei-Bei Chu

Journal: Autophagy

PubMed ID: 34822318

Doi: 10.1080/15548627.2021.2002101

Products & Services: Catalog Antibody

Novel xylan-degrading enzymes from polysaccharide utilizing loci of Prevotella copri DSM18205

Authors: Javier A Linares-Pastén , Johan Sebastian Hero , José Horacio Pisa , Cristina Teixeira , Margareta Nyman , Patrick Adlercreutz , M Alejandra Martinez , Eva Nordberg Karlsson

Journal: Glycobiology

PubMed ID: 34142143

Doi: 10.1093/glycob/cwab056

Products & Services: Gene Synthesis

Phylogenetic Analysis of the Plant U2 snRNP Auxiliary Factor Large Subunit A Gene Family in Response to Developmental Cues and Environmental Stimuli

Authors: Shuai Lu, Cong Gao, Yongzhou Wang, Yingying He, Junrong Du, Moxian Chen, Hua Zhao, Hui Fang, Baohua Wang, Yunying Cao

Journal: Front Plant Sci

PubMed ID: 34868124

Doi: 10.3389/fpls.2021.739671

Products & Services: Protein Tools

Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers

Authors: Orly Avraham, Edward A Bayer, Oded Livnah

Journal: FEBS J

PubMed ID: 34726340

Doi: 10.1111/febs.16259

Products & Services: Codon Optimization

Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants

Authors: Matthew McCallum, Alexandra C Walls, Kaitlin R Sprouse, John E Bowen, Laura E Rosen, Ha V Dang, Anna De Marco, Nicholas Franko, Sasha W Tilles, Jennifer Logue, Marcos C Miranda, Margaret Ahlrichs, Lauren Carter, Gyorgy Snell, Matteo Samuele Pizzuto, Helen Y Chu, Wesley C Van Voorhis, Davide Corti, David Veesler

Journal: Science

PubMed ID: 34751595

Doi: 10.1126/science.abl8506

Products & Services: Serology SARS-Cov-2 detection kits

Immune Responses to a Single Dose of the AZD1222/Covishield Vaccine at 16 Weeks in Individuals in Sri Lanka

Authors: Chandima Jeewandara, Dinuka Guruge, Pradeep Darshana Pushpakumara, Achala Kamaladasa, Inoka Sepali Aberathna, Shyrar Tanussiya Ramu, Banuri Gunasekera, Ayesha Wijesinghe, Osanda Dissanayake, Heshan Kuruppu, Thushali Ranasinghe, Deshni Jayathilaka, Shashika Dayarathna, Dinithi Ekanayake, Jeewantha Jayamali, Nayanathara Gamalath, Anushika Mudunkotiwa, Gayasha Somathilake, Madhushika Dissanayake, Michael Harvie, Thashmi Nimasha, Deshan Madusanka, Tibutius Jayadas, Ruwan Wijayamuni, Lisa Schimanski, Pramila Rijal, Tiong K Tan, Alain Townsend, Graham S Ogg, Gathsaurie Neelika Malavige

Journal: J Immunol

PubMed ID: 34750205

Doi: 10.4049/jimmunol.2100762

Products & Services: Recombinant Antibody Expression

α-Klotho released from HK-2 cells inhibits osteogenic differentiation of renal interstitial fibroblasts by inactivating the Wnt-β-catenin pathway

Authors: Zewu Zhu, Shuhao Ruan, Yingcheng Jiang, Fang Huang, Weiping Xia, Jinbo Chen, Yu Cui, Cheng He, Feng Zeng, Yang Li, Zhiyong Chen, Hequn Chen

Journal: Cell Mol Life Sci

PubMed ID: 34724098

Doi: 10.1007/s00018-021-03972-x

Products & Services: Proteins, Expression, Isolation and Analysis

Hydrolytically Stable Maleimide-End-Functionalized Polymers for Site-Specific Protein Conjugation

Authors: Thaiesha A Wright, Monica Sharfin Rahman, Camaryn Bennett, Madolynn R Johnson, Henry Fischesser, Natasha Ram, Amoni Tyler, Richard C Page, Dominik Konkolewicz

Journal: Bioconjug Chem

PubMed ID: 34730954

Doi: 10.1021/acs.bioconjchem.1c00487

Products & Services: Plasmid DNA Preparation

LDH nanoparticle adjuvant subunit vaccine induces an effective immune response for porcine epidemic diarrhea virus

Authors: Danyi Shi, Baochao Fan, Bing Sun, Jinzhu Zhou, Yongxiang Zhao, Rongli Guo, Zengjun Ma, Tao Song, Huiying Fan, Jizong Li, Li Li, Bin Li

Journal: Virology

PubMed ID: 34739917

Doi: 10.1016/j.virol.2021.10.010

Products & Services: Plasmid DNA Preparation

Polyactin A and CpG enhance inactivated Pseudomonas plecoglossicida vaccine potency in large yellow croaker (Larimichthys crocea)

Authors: Wenwen Wang, Wei Wang, Wenjun Xu, Qin Liu, Yuanxing Zhang, Xiaohong Liu

Journal: Fish Shellfish Immunol

PubMed ID: 34780977

Doi: 10.1016/j.fsi.2021.11.008

Products & Services: Plasmid DNA Preparation

STING inhibition accelerates the bone healing process while enhancing type H vessel formation

Authors: Xiaojun Chen, Wenxin He, Mengzhe Sun, Yingjie Yan, Yichuan Pang, Gang Chai

Journal: FASEB J

PubMed ID: 34694030

Doi: 10.1096/fj.202100069RR

Products & Services: Nucleic Acid Purification & Analysis

Structural basis and mechanism of activation of two different families of G proteins by the same GPCR

Authors: Kamela O Alegre, Navid Paknejad, Minfei Su, Jian-Shu Lou, Jianyun Huang, Kelsey D Jordan, Edward T Eng, Joel R Meyerson, Richard K Hite, Xin-Yun Huang

Journal: Nat Struct Mol Biol

PubMed ID: 34759376

Doi: 10.1038/s41594-021-00679-2

Products & Services: Mutant Libraries

Circular RNA hsa_circ_0043278 inhibits breast cancer progression via the miR-455-3p/EI24 signalling pathway

Authors: Yue Shi, Chong Liu

Journal: BMC Cancer

PubMed ID: 34800978

Doi: 10.1186/s12885-021-08989-w

Products & Services: Mutant Libraries

Mapping enzyme catalysis with metabolic biosensing

Authors: Linfeng Xu, Kai-Chun Chang, Emory M Payne, Cyrus Modavi, Leqian Liu, Claire M Palmer, Nannan Tao, Hal S Alper, Robert T Kennedy, Dale S Cornett, Adam R Abate

Journal: Nat Commun

PubMed ID: 34815408

Doi: 10.1038/s41467-021-27185-9

Products & Services: Mutagenesis Services

SpSR-B2 functions as a potential pattern recognition receptor involved in antiviral and antibacterial immune responses of mud crab Scylla paramamosain

Authors: Jian Zhou, Jun-Fang Zhou, Yue Wang, Guang-Peng Feng, Wen-Hong Fang, Wei Kang, Ling-Bo Ma, Xin-Cang Li

Journal: Int J Biol Macromol

PubMed ID: 34780895

Doi: 10.1016/j.ijbiomac.2021.11.048

Products & Services: Monoclonal Antibody Services

Photoredox-Catalyzed Decarboxylative -Terminal Differentiation for Bulk- and Single-Molecule Proteomics

Authors: Le Zhang, Brendan M Floyd, Maheshwerreddy Chilamari, James Mapes, Jagannath Swaminathan, Steven Bloom, Edward M Marcotte, Eric V Anslyn

Journal: ACS Chem Biol

PubMed ID: 34734691

Doi: 10.1021/acschembio.1c00631

Products & Services: Mammalian Expression

Elevated Fab glycosylation of anti-hinge antibodies

Authors: J Koers, Nil Derksen, Wjj Falkenburg, P Ooijevaar-de Heer, M T Nurmohamed, G J Wolbink, T Rispens

Journal: Scand J Rheumatol

PubMed ID: 34726124

Doi: 10.1080/03009742.2021.1986959

Products & Services: GenParts™ DNA Fragments

Using recombinant adhesive proteins as durable and green flame-retardant coatings

Authors: Weng I Leong, Owen Lok In Lo, Fong Tin Cheng, Wai Man Cheong, Leo Chi U Seak

Journal: Synth Syst Biotechnol

PubMed ID: 34786512

Doi: 10.1016/j.synbio.2021.10.005

Products & Services: GenParts™ DNA Fragments

Structure and Function of a Dual Reductase-Dehydratase Enzyme System Involved in -Terphenyl Biosynthesis

Authors: Jonathan A Clinger, Yinan Zhang, Yang Liu, Mitchell D Miller, Ronnie E Hall, Steven G Van Lanen, George N Phillips, Jon S Thorson, Sherif I Elshahawi

Journal: ACS Chem Biol

PubMed ID: 34763417

Doi: 10.1021/acschembio.1c00701

Products & Services: GenParts™ DNA Fragments

Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp YS-1 and characterization of two initial degrading esterases

Authors: Na Shang, Lingling Chen, Minggen Cheng, Yanning Tian, Xing Huang

Journal: Sci Total Environ

PubMed ID: 34742792

Doi: 10.1016/j.scitotenv.2021.151357

Products & Services: DNA Sequencing

Structural and functional insights into the spike protein mutations of emerging SARS-CoV-2 variants

Authors: Deepali Gupta, Priyanka Sharma, Mandeep Singh, Mukesh Kumar, A S Ethayathulla, Punit Kaur

Journal: Cell Mol Life Sci

PubMed ID: 34731254

Doi: 10.1007/s00018-021-04008-0

Products & Services: DNA Sequencing

Prokaryotic expression, evaluation, and prediction of the structure and function of the ecarin metalloproteinase domain

Authors: Nasrin Mohammadi, Mojgan Bandehpour, Fattah Sotoodehnejadnematalahi, Bahram Kazemi

Journal: Proteins

PubMed ID: 34739152

Doi: 10.1002/prot.26275

Products & Services: Custom Vector Construction

African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis

Authors: Tingting Li, Gaihong Zhao, Taoqing Zhang, Zhaoxia Zhang, Xin Chen, Jie Song, Xiao Wang, Jiangnan Li, Li Huang, Lili Wen, Changyao Li, Dongming Zhao, Xijun He, Zhigao Bu, Jun Zheng, Changjiang Weng

Journal: Viruses

PubMed ID: 34835046

Doi: 10.3390/v13112240

Products & Services: Custom Vector Construction

5' Half of specific tRNAs feeds back to promote corresponding tRNA gene transcription in vertebrate embryos

Authors: Luxi Chen, Wei Xu, Kunpeng Liu, Zheng Jiang, Yang Han, Hongbin Jin, Lin Zhang, Weimin Shen, Shunji Jia, Qianwen Sun, Anming Meng

Journal: Sci Adv

PubMed ID: 34797706

Doi: 10.1126/sciadv.abh0494

Products & Services: Custom Vector Construction

Cyclophilin A is a key positive and negative feedback regulator within interleukin-6 trans-signaling pathway

Authors: Xiaohan Luan, Wenxian Yang, Xiaoyuan Bai, Heqiao Li, Huizi Li, Wenhui Fan, He Zhang, Wenjun Liu, Lei Sun

Journal: FASEB J

PubMed ID: 34606626

Doi: 10.1096/fj.202101044RRR

Products & Services: Custom Vector Construction

A structural feature of Dda helicase which enhances displacement of streptavidin and trp repressor from DNA

Authors: Alicia K Byrd, Emory G Malone, Lindsey Hazeslip, Maroof Khan Zafar, David K Harrison, Matthew D Thompson, Jun Gao, Senthil K Perumal, John C Marecki, Kevin D Raney

Journal: Protein Sci

PubMed ID: 34761452

Doi: 10.1002/pro.4232

Products & Services: Codon Optimization

Identification and Characterization of Antigen-Specific CD8 T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing

Authors: Shaheed Abdulhaqq, Abigail B Ventura, Jason S Reed, Arman A Bashirova, Katherine B Bateman, Eric McDonald, Helen L Wu, Justin M Greene, John B Schell, David Morrow, Karin Wisskirchen, Jeffrey N Martin, Steven G Deeks, Mary Carrington, Ulrike Protzer, Klaus Früh, Scott G Hansen, Louis J Picker, Jonah B Sacha, Benjamin N Bimber

Journal: J Immunol

PubMed ID: 34810222

Doi: 10.4049/jimmunol.2100535

Products & Services: Catalog Peptides

The Ionic Selectivity of Lysenin Channels in Open and Sub-Conducting States

Authors: Andrew Bogard, Pangaea W Finn, Fulton McKinney, Ilinca M Flacau, Aviana R Smith, Rosey Whiting, Daniel Fologea

Journal: Membranes (Basel)

PubMed ID: 34832126

Doi: 10.3390/membranes11110897

Products & Services: Catalog Antibody

SARS-CoV-2 Infection of Rhesus Macaques Treated Early with Human COVID-19 Convalescent Plasma

Authors: Jesse D Deere, Timothy D Carroll, Joseph Dutra, Linda Fritts, Rebecca Lee Sammak, JoAnn L Yee, Katherine J Olstad, J Rachel Reader, Amy Kistler, Jack Kamm, Clara Di Germanio, Yashavanth Shaan Lakshmanappa, Sonny R Elizaldi, Jamin W Roh, Graham Simmons, Jennifer Watanabe, Rachel E Pollard, Jodie Usachenko, Ramya Immareddy, Brian A Schmidt, Shelby L O'Connor, Joseph DeRisi, Michael P Busch, Smita S Iyer, Koen K A Van Rompay, Dennis J Hartigan-O'Connor, Christopher J Miller

Journal: Microbiol Spectr

PubMed ID: 34817208

Doi: 10.1128/Spectrum.01397-21

Products & Services: Recombinant Proteins

Retinol-Binding Protein 4 Promotes Cardiac Injury After Myocardial Infarction Via Inducing Cardiomyocyte Pyroptosis Through an Interaction With NLRP3

Authors: Kang-Zhen Zhang, Xi-Yu Shen, Man Wang, Li Wang, Hui-Xian Sun, Xiu-Zhen Li, Jing-Jing Huang, Xiao-Qing Li, Cheng Wu, Can Zhao, Jia-Li Liu, Xiang Lu, Wei Gao

Journal: J Am Heart Assoc

PubMed ID: 34726071

Doi: 10.1161/JAHA.121.022011

Products & Services: Recombinant Proteins Protein Tools

Management of COVID patients with convalescent plasma: Do we have the final word?

Authors: Francesco Menichetti, Marco Falcone, Giusy Tiseo

Journal: Eur J Intern Med

PubMed ID: 34895816

Doi: 10.1016/j.ejim.2021.10.029

Products & Services: Recombinant Proteins

A study of cobalt (II) complexes involved in marine biogeochemical processes: Co(II)-1,10-Phenanthroline and Co(II)-1,10-Phenanthroline-L-α-Phosphatidylcholine

Authors: Anđela Bačinić, Sanja Frka, Marina Mlakar

Journal: Bioelectrochemistry

PubMed ID: 34902665

Doi: 10.1016/j.bioelechem.2021.108009

Products & Services: Peptide Synthesis

Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies

Authors: Anilkumar Gopalakrishnapillai, Colin E Correnti, Kristina Pilat, Ida Lin, Man Kid Chan, Ashok D Bandaranayake, Christopher Mehlin, Anne Kisielewski, Darcy Hamill, Allison J Kaeding, Soheil Meshinchi, James M Olson, Edward Anders Kolb, Sonali P Barwe

Journal: Cancers (Basel)

PubMed ID: 34885074

Doi: 10.3390/cancers13235964

Products & Services: Gene Synthesis

Overexpression of N-acetylglucosaminyltransferase V promotes human parotid gland acinar cell immortalization via the epidermal receptor activation

Authors: Ching-Chia Cheng, Chih-Feng Lin, Yong-Chong Lin, Tai-Horng Young, Pei-Jen Lou

Journal: J Cell Physiol

PubMed ID: 34806177

Doi: 10.1002/jcp.30641

Products & Services: Proteins, Expression, Isolation and Analysis

Nucleic Acid Delivery from Granular Hydrogels

Authors: Evan Kurt, Tatiana Segura

Journal: Adv Healthc Mater

PubMed ID: 34742164

Doi: 10.1002/adhm.202101867

Products & Services: Proteins, Expression, Isolation and Analysis

Assembly of pH-Responsive Antibody-Drug-Inspired Conjugates

Authors: Marco Raabe, Astrid Johanna Heck, Siska Führer, Dominik Schauenburg, Michaela Pieszka, Tao Wang, Maksymilian Marek Zegota, Lutz Nuhn, David Y W Ng, Seah Ling Kuan, Tanja Weil

Journal: Macromol Biosci

PubMed ID: 34791790

Doi: 10.1002/mabi.202100299

Products & Services: Proteins, Expression, Isolation and Analysis