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The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione

Authors: Mana Murae, Yoshimi Shimizu, Yuichiro Yamamoto, Asuka Kobayashi, Masumi Houri, Tetsuya Inoue, Takuya Irie, Ryutaro Gemba, Yosuke Kondo, Yoshio Nakano, Satoru Miyazaki, Daisuke Yamada, Akiyoshi Saitoh, Isao Ishii, Taishi Onodera, Yoshimasa Takahashi, Takaji Wakita, Masayoshi Fukasawa, Kohji Noguchi

Journal: Biochem Biophys Res Commun

PubMed ID: 35123263

Doi: 10.1016/j.bbrc.2022.01.106

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The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione

Journal: Biochem Biophys Res Commun

PubMed ID: 35123263

Doi: 10.1016/j.bbrc.2022.01.106

Products & Services: Monoclonal Antibody Services

lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway

Authors: Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang

Journal: Mediators Inflamm

PubMed ID: 35125964

Doi: 10.1155/2022/6979117

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Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model

Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto

Journal: Toxics

PubMed ID: 35051082

Doi: 10.3390/toxics10010040

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Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model

Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto

Journal: Toxics

PubMed ID: 35051082

Doi: 10.3390/toxics10010040

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theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions

Authors: Teresa Lopes Gomes, Virgínia de Oliveira-Marques, Richard John Hampson, António Jacinto, Luciana Vieira de Moraes, Rui Gonçalo Martinho

Journal: Front Pharmacol

PubMed ID: 35069190

Doi: 10.3389/fphar.2021.752787

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Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR

Authors: Zhenyu Wang, Jing Chen, Qiong-Ge Zhang, Kai Huang, Dan Ma, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 35085949

Doi: 10.1016/j.vetmic.2022.109354

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Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase

Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek

Journal: Cells

PubMed ID: 35011726

Doi: 10.3390/cells11010165

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Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase

Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek

Journal: Cells

PubMed ID: 35011726

Doi: 10.3390/cells11010165

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Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants

Authors: Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran

Journal: Viruses

PubMed ID: 35215823

Doi: 10.3390/v14020230

Products & Services: Recombinant Proteins

Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome

Authors: Juan Manuel Orozco Rodriguez, Ewa Krupinska, Hanna Wacklin-Knecht, Wolfgang Knecht

Journal: Nucleosides Nucleotides Nucleic Acids

PubMed ID: 35094635

Doi: 10.1080/15257770.2021.2023749

Products & Services: Plasmid DNA Preparation

Development of a Salmonella-based oral vaccine to control intestinal colonization of Shiga-toxin-producing Escherichia coli (STEC) in animals

Authors: Florencia Iannino, Paula J Uriza, Cecilia M Duarte, María V Pepe, Mara S Roset, Gabriel Briones

Journal: Vaccine

PubMed ID: 35086742

Doi: 10.1016/j.vaccine.2022.01.032

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HOTAIR Induces the Downregulation of miR-200 Family Members in Gastric Cancer Cell Lines

Authors: Fatemeh Bossaghzadeh, Mohammadreza Hajjari, Abdolkarim Sheikhi, Iman Salahshourifar, Shiva Irani

Journal: Iran Biomed J

PubMed ID: 34923813

Doi: 10.52547/ibj.26.1.77

Products & Services: Molecular Biology Tools

Mesenchymal Stem Cell-Derived Exosomes Improved Cerebral Infarction via Transferring miR-23a-3p to Activate Microglia

Authors: Chenglong Dong, Maogang Chen, Binggang Cai, Cheng Zhang, Guodong Xiao, Weifeng Luo

Journal: Neuromolecular Med

PubMed ID: 35001328

Doi: 10.1007/s12017-021-08686-8

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Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages

Authors: Fangfang Yu, Wenxia Tian, Jie Dong

Journal: Int Immunopharmacol

PubMed ID: 35045357

Doi: 10.1016/j.intimp.2021.108514

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RBP4 regulates androgen receptor expression and steroid synthesis in Sertoli cells from Bactrian camels

Authors: Qi Wang, Quanwei Zhang, Yina Li, Xingxu Zhao, Yong Zhang

Journal: Reprod Domest Anim

PubMed ID: 35014100

Doi: 10.1111/rda.14081

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Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells

Authors: Xiaohong Zhang, Stephen H Wright

Journal: Int J Mol Sci

PubMed ID: 35163393

Doi: 10.3390/ijms23031472

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Solid-Phase Extraction Approaches for Improving Oligosaccharide and Small Peptide Identification with Liquid Chromatography-High-Resolution Mass Spectrometry: A Case Study on Proteolyzed Almond Extract

Authors: Yu-Ping Huang, Randall C Robinson, Fernanda Furlan Goncalves Dias, Juliana Maria Leite Nobrega de Moura Bell, Daniela Barile

Journal: Foods

PubMed ID: 35159490

Doi: 10.3390/foods11030340

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Assessment on anti-SARS-CoV-2 receptor-binding domain antibodies among CoronaVac-vaccinated Indonesian adults

Authors: Juandy Jo, Astia Sanjaya, Reinhard Pinontoan, Maroloan Aruan, Rury Mega Wahyuni, Venansi Viktaria

Journal: Clin Exp Vaccine Res

PubMed ID: 35223672

Doi: 10.7774/cevr.2022.11.1.116

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LbCas12a-D156R Efficiently Edits Effector Binding Elements to Generate Canker-Resistant Citrus Plants

Authors: Hongge Jia, Yuanchun Wang, Hang Su, Xiaoen Huang, Nian Wang

Journal: Cells

PubMed ID: 35159125

Doi: 10.3390/cells11030315

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SARS-CoV-2 Seroprevalence Among Whole Blood Donors During First Wave of Covid-19 Pandemic in India

Authors: Srinivasa Rao Chunchu, Ushasree Ravula, Vikram Kumar Gente, Srinivas Bacchu, S Pandu Ranga Rao, Srujaleswari Mooli

Journal: Indian J Hematol Blood Transfus

PubMed ID: 35125705

Doi: 10.1007/s12288-021-01512-y

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Heterologous immunization with BNT162b2 followed by mRNA-1273 in dialysis patients: seroconversion and presence of neutralizing antibodies

Authors: Niko Kohmer, Holger F Rabenau, Sandra Ciesek, Bernhard K Krämer, Uwe Göttmann, Christine Keller, Daniela Rose, Carsten Blume, Michael Thomas, Alexander Lammert, Anne Lammert

Journal: Nephrol Dial Transplant

PubMed ID: 35099023

Doi: 10.1093/ndt/gfac018

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Development of an enzymatic method for the evaluation of protein deposition on contact lenses

Authors: Simin Masoudi, Mark Willcox

Journal: Biofouling

PubMed ID: 35016572

Doi: 10.1080/08927014.2021.2019225

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Penetration of the SARS-CoV-2 Spike Protein across the Blood-Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing

Authors: Dániel Petrovszki, Fruzsina R Walter, Judit P Vigh, Anna Kocsis, Sándor Valkai, Mária A Deli, András Dér

Journal: Biomedicines

PubMed ID: 35052867

Doi: 10.3390/biomedicines10010188

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Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites

Authors: Bruna Felício Milazzotto Maldonado Porchia, Luana Raposo de Melo Moraes Aps, Ana Carolina Ramos Moreno, Jamile Ramos da Silva, Mariângela de Oliveira Silva, Natiely Silva Sales, Rubens Prince Dos Santos Alves, Clarissa Ribeiro Reily Rocha, Matheus Molina Silva, Karine Bitencourt Rodrigues, Tácita Borges Barros, Roberta Liberato Pagni, Patrícia da Cruz Souza, Mariana de Oliveira Diniz, Luís Carlos de Souza Ferreira

Journal: Int J Biol Sci

PubMed ID: 34975315

Doi: 10.7150/ijbs.56644

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Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice

Authors: Yi Zhang, Mufan Ji, Zhenyang Gu, Wenlong Pei, Jun Zhu, Qian Wu, Lei Li, Zhan Zhang

Journal: Toxicology

PubMed ID: 34979169

Doi: 10.1016/j.tox.2021.153088

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Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations

Authors: Anju Jaiswal, D Dash, Rashmi Singh

Journal: Toxicol Appl Pharmacol

PubMed ID: 34998855

Doi: 10.1016/j.taap.2021.115861

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Targeted deletion of liver-expressed Choriogenin L results in the production of soft eggs and infertility in medaka, Oryzias latipes

Authors: Kenji Murata, Masato Kinoshita

Journal: Zoological Lett

PubMed ID: 34983666

Doi: 10.1186/s40851-021-00185-9

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miR-541-3p Promoted Porcine Reproductive and Respiratory Syndrome Virus 2 (PRRSV-2) Replication by Targeting Interferon Regulatory Factor 7

Authors: Xibao Shi, Yuanhao Yang, Xiaozhuan Zhang, Xiaobo Chang, Jing Chen, Chao Wang, Aiping Wang, Jianhua Wang, Jianru Qin, Xianlong Ye, Wei Jin, Gaiping Zhang

Journal: Viruses

PubMed ID: 35062330

Doi: 10.3390/v14010126

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Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours

Authors: Xiaoyu Yu, Ying Bai, Bing Han, Minzi Ju, Tianci Tang, Ling Shen, Mingyue Li, Li Yang, Zhao Zhang, Guoku Hu, Jie Chao, Yuan Zhang, Honghong Yao

Journal: J Extracell Vesicles

PubMed ID: 35029057

Doi: 10.1002/jev2.12185

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Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours

Authors: Xiaoyu Yu, Ying Bai, Bing Han, Minzi Ju, Tianci Tang, Ling Shen, Mingyue Li, Li Yang, Zhao Zhang, Guoku Hu, Jie Chao, Yuan Zhang, Honghong Yao

Journal: J Extracell Vesicles

PubMed ID: 35029057

Doi: 10.1002/jev2.12185

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Safety and Immunogenicity of the Third Booster Dose with Inactivated, Viral Vector, and mRNA COVID-19 Vaccines in Fully Immunized Healthy Adults with Inactivated Vaccine

Authors: Sitthichai Kanokudom, Suvichada Assawakosri, Nungruthai Suntronwong, Chompoonut Auphimai, Pornjarim Nilyanimit, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Ritthideach Yorsaeng, Donchida Srimuan, Thaksaporn Thatsanatorn, Sirapa Klinfueng, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Sittisak Honsawek, Yong Poovorawan

Journal: Vaccines (Basel)

PubMed ID: 35062747

Doi: 10.3390/vaccines10010086

Cloning and Functional Characterization of a Double-Stranded RNA-Degrading Nuclease in the Tawny Crazy Ant ()

Authors: Jiaxin Lei, Yongan Tan, Fabian List, Robert Puckett, Aaron M Tarone, Edward L Vargo, Keyan Zhu-Salzman

Journal: Front Physiol

PubMed ID: 35153841

Doi: 10.3389/fphys.2022.833652

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UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells

Authors: Natasha Salame, Jean-Pierre Bikorimana, Nehme El-Hachem, Wael Saad, Mazen Kurdi, Jing Zhao, Nicoletta Eliopoulos, Riam Shammaa, Moutih Rafei

Journal: Stem Cell Res Ther

PubMed ID: 35012668

Doi: 10.1186/s13287-021-02693-z

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Ginger nanoparticles mediated induction of Foxa2 prevents high-fat diet-induced insulin resistance

Authors: Anil Kumar, Kumaran Sundaram, Yun Teng, Jingyao Mu, Mukesh K Sriwastva, Lifeng Zhang, Joshua L Hood, Jun Yan, Xiang Zhang, Juw Won Park, Michael L Merchant, Huang-Ge Zhang

Journal: Theranostics

PubMed ID: 35154496

Doi: 10.7150/thno.62514

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Plant-Based Vaccines in Combat against Coronavirus Diseases

Authors: Benita Ortega-Berlanga, Tomasz Pniewski

Journal: Vaccines (Basel)

PubMed ID: 35214597

Doi: 10.3390/vaccines10020138

Products & Services: Protein Electrophoresis and Western

NMR Detection and Structural Modeling of the Ethylene Receptor LeETR2 from Tomato

Authors: Shukun Wei, Yaqing Yang, Yuan Yuan, Lingyu Du, Hongjuan Xue, Bo OuYang

Journal: Membranes (Basel)

PubMed ID: 35207029

Doi: 10.3390/membranes12020107

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Silencing of circCDC14A prevents cerebral ischemia-reperfusion injury via miR-23a-3p/CXCL12 axis

Authors: Huiyi Huo, Chao Hu, Yongxue Lu, Jinyu Zhou, Zhiguang Mai

Journal: J Biochem Mol Toxicol

PubMed ID: 34978116

Doi: 10.1002/jbt.22982

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Mitochondrial Dysfunction Associates With Acute T Lymphocytopenia and Impaired Functionality in COVID-19 Patients

Authors: Yufei Mo, Kelvin Kai-Wang To, Runhong Zhou, Li Liu, Tianyu Cao, Haode Huang, Zhenglong Du, Chun Yu Hubert Lim, Lok-Yan Yim, Tsz-Yat Luk, Jacky Man-Chun Chan, Thomas Shiu-Hong Chik, Daphne Pui-Ling Lau, Owen Tak-Yin Tsang, Anthony Raymond Tam, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Zhiwei Chen

Journal: Front Immunol

PubMed ID: 35095881

Doi: 10.3389/fimmu.2021.799896

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Immunogenicity of Oxford-AstraZeneca COVID-19 Vaccine in Vietnamese Health-Care Workers

Authors: Nguyen Van Vinh Chau, Lam Anh Nguyet, Nguyen Thanh Truong, Le Mau Toan, Nguyen Thanh Dung, Le Manh Hung, Mai Thanh Nhan, Dinh Nguyen Huy Man, Nghiem My Ngoc, Huynh Phuong Thao, Tran Nguyen Hoang Tu, Huynh Kim Mai, Do Thai Hung, Nguyen Thi Han Ny, Le Kim Thanh, Nguyen To Anh, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Lam Minh Yen, Marc Choisy, Tran Tan Thanh, Guy Thwaites, Le Van Tan

Journal: Am J Trop Med Hyg

PubMed ID: 34996048

Doi: 10.4269/ajtmh.21-0849

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The Predictive Efficacy of Serum Exosomal microRNA-122 and microRNA-148a for Hepatocellular Carcinoma Based on Smart Healthcare

Authors: Peng Deng, Mi Li, Yuni Wu

Journal: J Healthc Eng

PubMed ID: 35028121

Doi: 10.1155/2022/5914541

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Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer

Authors: Junko Matsuzaki, Shashikant Lele, Kunle Odunsi, Takemasa Tsuji

Journal: Oncoimmunology

PubMed ID: 35003898

Doi: 10.1080/2162402X.2021.2020983

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Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer

Authors: Junko Matsuzaki, Shashikant Lele, Kunle Odunsi, Takemasa Tsuji

Journal: Oncoimmunology

PubMed ID: 35003898

Doi: 10.1080/2162402X.2021.2020983

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Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells

Authors: Bruna Cristina Falavinha, María Julia Barisón, Carmen Lúcia Kuniyoshi Rebelatto, Bruna Hilzendeger Marcon, Alessandra de Melo Aguiar, Evelin Brandão da Silva, Marco Augusto Stimamiglio, Patrícia Shigunov

Journal: Stem Cells Int

PubMed ID: 35047041

Doi: 10.1155/2022/4930932

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Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus

Authors: Liqi Liu, Zi Li, Jianfang Zhou, Jia Liu, Xiyan Li, Weijuan Huang, Ning Xiao, Dayan Wang

Journal: Influenza Other Respir Viruses

PubMed ID: 35037399

Doi: 10.1111/irv.12954

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Genome-wide characterization of Histone gene family and expression profiling during microspore development in radish (Raphanus sativus L)

Authors: Qijiao Wang, Lianxue Fan, Xiaojun Su, Jiali Ying, Liang Xu, Cui Li, Yan Wang, Liwang Liu

Journal: Gene

PubMed ID: 34990794

Doi: 10.1016/j.gene.2021.146180

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Isoforms of the neuropeptide myosuppressin differentially modulate the cardiac neuromuscular system of the American lobster,

Authors: Emily R Oleisky, Meredith E Stanhope, J Joe Hull, Patsy S Dickinson

Journal: J Neurophysiol

PubMed ID: 35044860

Doi: 10.1152/jn.00338.2021

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Elucidating the 3D Structure of a Surface Membrane Antigen from as a Serodiagnostic Biomarker of Chagas Disease

Authors: Flavio Di Pisa, Stefano De Benedetti, Enrico Mario Alessandro Fassi, Mauro Bombaci, Renata Grifantini, Angelo Musicò, Roberto Frigerio, Angela Pontillo, Cinzia Rigo, Sandra Abelli, Romualdo Grande, Nadia Zanchetta, Davide Mileto, Alessandro Mancon, Alberto Rizzo, Alessandro Gori, Marina Cretich, Giorgio Colombo, Martino Bolognesi, Louise Jane Gourlay

Journal: Vaccines (Basel)

PubMed ID: 35062732

Doi: 10.3390/vaccines10010071

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The ectomycorrhizal basidiomycete Laccaria bicolor releases a GH28 polygalacturonase that plays a key role in symbiosis establishment

Authors: Feng Zhang, Aurore Labourel, Mireille Haon, Minna Kemppainen, Emilie Da Silva Machado, Nicolas Brouilly, Claire Veneault-Fourrey, Annegret Kohler, Marie-Noëlle Rosso, Alejandro Pardo, Bernard Henrissat, Jean-Guy Berrin, Francis Martin

Journal: New Phytol

PubMed ID: 34942023

Doi: 10.1111/nph.17940

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Mechanism of MyD88S mediated signal termination

Authors: Katarzyna Pustelny, Katarzyna Kuska, Andrzej Gorecki, Bogdan Musielak, Ewelina Dobosz, Benedykt Wladyka, Joanna Koziel, Anna Czarna, Tad Holak, Grzegorz Dubin

Journal: Cell Commun Signal

PubMed ID: 35057808

Doi: 10.1186/s12964-021-00811-1

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Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

Authors: Diego Angosto-Bazarra, Cristina Alarcón-Vila, Laura Hurtado-Navarro, María C Baños, Jack Rivers-Auty, Pablo Pelegrín

Journal: BMC Biol

PubMed ID: 34996441

Doi: 10.1186/s12915-021-01220-z

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Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden

Authors: Julia Femel, Luuk van Hooren, Melanie Herre, Jessica Cedervall, Falk Saupe, Elisabeth J M Huijbers, Danielle R J Verboogen, Matthias Reichel, Victor L Thijssen, Arjan W Griffioen, Lars Hellman, Anna Dimberg, Anna-Karin Olsson

Journal: Cancer Immunol Immunother

PubMed ID: 35018481

Doi: 10.1007/s00262-021-03139-4

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A murine Skint6 W168X allele contributes to autoimmune disease in a transgenic model

Authors: Jiyu Ju, Hui Wang, Meng Lian, Yatao Bao, Yanyan Zhang, Zhiwei Xu

Journal: Lupus

PubMed ID: 35045734

Doi: 10.1177/09612033221074544

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Severe Natural Outbreak of in Gilthead Seabream Produces Leukocyte Mobilization and Innate Immunity at the Gill Tissue

Authors: Laura Cervera, Carmen González-Fernández, Marta Arizcun, Alberto Cuesta, Elena Chaves-Pozo

Journal: Int J Mol Sci

PubMed ID: 35055122

Doi: 10.3390/ijms23020937

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GRIM-19 is a target of mycobacterial Zn metalloprotease 1 and indispensable for NLRP3 inflammasome activation

Authors: Tomomi Kurane, Tetsuro Matsunaga, Tomoaki Ida, Kazuko Sawada, Akira Nishimura, Masayuki Fukui, Masayuki Umemura, Masaaki Nakayama, Naoya Ohara, Sohkichi Matsumoto, Takaaki Akaike, Goro Matsuzaki, Giichi Takaesu

Journal: FASEB J

PubMed ID: 34907600

Doi: 10.1096/fj.202101074RR

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Efficacy of Convalescent Plasma to Treat Mild to Moderate COVID-19 in Kidney Transplant Patients: A Propensity Score Matching Analysis

Authors: Marina Pontello Cristelli, Dante Mário Langhi Junior, Laila Almeida Viana, Luis Gustavo Modelli de Andrade, Suelen Bianca Stopa Martins, Yasmim Cardoso Dreige, José Orlando Bordim, Helio Tedesco-Silva, José Medina-Pestana

Journal: Transplantation

PubMed ID: 34581314

Doi: 10.1097/TP.0000000000003962

Recognition and Chaperoning by Pex19, Followed by Trafficking and Membrane Insertion of the Peroxisome Proliferation Protein, Pex11

Authors: Katarzyna M Zientara-Rytter, Shanmuga S Mahalingam, Jean-Claude Farré, Krypton Carolino, Suresh Subramani

Journal: Cells

PubMed ID: 35011719

Doi: 10.3390/cells11010157

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The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a

Authors: Luiza Mamigonian Bessa, Serafima Guseva, Aldo R Camacho-Zarco, Nicola Salvi, Damien Maurin, Laura Mariño Perez, Maiia Botova, Anas Malki, Max Nanao, Malene Ringkjøbing Jensen, Rob W H Ruigrok, Martin Blackledge

Journal: Sci Adv

PubMed ID: 35044811

Doi: 10.1126/sciadv.abm4034

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Minc03328 effector gene downregulation severely affects Meloidogyne incognita parasitism in transgenic Arabidopsis thaliana

Authors: Valdeir Junio Vaz Moreira, Isabela Tristan Lourenço-Tessutti, Marcos Fernando Basso, Maria Eugênia Lisei-de-Sa, Carolina Vianna Morgante, Bruno Paes-de-Melo, Fabrício Barbosa Monteiro Arraes, Diogo Martins-de-Sa, Maria Cristina Mattar Silva, Janice de Almeida Engler, Maria Fatima Grossi-de-Sa

Journal: Planta

PubMed ID: 35050413

Doi: 10.1007/s00425-022-03823-4

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Viral immune evasins impact antigen presentation by allele-specific trapping of MHC I at the peptide-loading complex

Authors: Sunesh Sethumadhavan, Marie Barth, Robbert M Spaapen, Carla Schmidt, Simon Trowitzsch, Robert Tampé

Journal: Sci Rep

PubMed ID: 35087068

Doi: 10.1038/s41598-022-05000-9

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Long-Term High-Fat Diet Consumption Depletes Glial Cells and Tyrosine Hydroxylase-Containing Neurons in the Brain of Middle-Aged Rats

Authors: Mei-Chuan Chou, Hsiang-Chun Lee, Yen-Chin Liu, Patrick Szu-Ying Yen, Ching-Kuan Liu, Chu-Huang Chen, Tzu-Han Hsieh, Shiou-Lan Chen

Journal: Cells

PubMed ID: 35053411

Doi: 10.3390/cells11020295

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Development of Peptide Targeted PLGA-PEGylated Nanoparticles Loading Licochalcone-A for Ocular Inflammation

Authors: Ruth Galindo, Elena Sánchez-López, María José Gómara, Marta Espina, Miren Ettcheto, Amanda Cano, Isabel Haro, Antoni Camins, María Luisa García

Journal: Pharmaceutics

PubMed ID: 35214019

Doi: 10.3390/pharmaceutics14020285

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Fifty Shades of E: Innate Immune Evasion by the Viral Endonucleases of All Pestivirus Species

Authors: Elena de Martin, Matthias Schweizer

Journal: Viruses

PubMed ID: 35215858

Doi: 10.3390/v14020265

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Cardiac troponin T and autoimmunity in skeletal muscle aging

Authors: Tan Zhang, Xin Feng, Juan Dong, Zherong Xu, Bo Feng, Karen M Haas, Peggy M Cawthon, Kristen M Beavers, Barbara Nicklas, Stephen Kritchevsky

Journal: Geroscience

PubMed ID: 35034279

Doi: 10.1007/s11357-022-00513-7

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CRISPR guides induce gene silencing in plants in the absence of Cas

Authors: Veerendra Kumar Sharma, Sandeep Marla, Wenguang Zheng, Divya Mishra, Jun Huang, Wei Zhang, Geoffrey Preston Morris, David Edward Cook

Journal: Genome Biol

PubMed ID: 34980227

Doi: 10.1186/s13059-021-02586-7

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De Novo Transcriptome of (Cactaceae) under In Vitro Conditions and Identification of Glyoxalase Genes

Authors: Carolina Enríquez-González, Cristina Garcidueñas-Piña, Osvaldo Adrián Castellanos-Hernández, Sergio Enríquez-Aranda, Abraham Loera-Muro, Gilberto Ocampo, Eugenio Pérez-Molphe Balch, José Francisco Morales-Domínguez

Journal: Plants (Basel)

PubMed ID: 35161380

Doi: 10.3390/plants11030399

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Objective to identify and verify the regulatory mechanism of DTNBP1 as a prognostic marker for hepatocellular carcinoma

Authors: Xianyi Cheng, Dezhi Li, Tiangyang Qi, Jia Sun, Tao Zhou, Wei V Zheng

Journal: Sci Rep

PubMed ID: 34997064

Doi: 10.1038/s41598-021-04055-4

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Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability

Authors: Wei Shi, Lingshu Wang, Tongqing Zhou, Mallika Sastry, Eun Sung Yang, Yi Zhang, Man Chen, Xuejun Chen, Misook Choe, Adrian Creanga, Kwan Leung, Adam S Olia, Amarendra Pegu, Reda Rawi, Chen-Hsiang Shen, Erik-Stephane D Stancofski, Chloe Adrienna Talana, I-Ting Teng, Shuishu Wang, Kizzmekia S Corbett, Yaroslav Tsybovsky, John R Mascola, Peter D Kwong

Journal: biorxiv

PubMed ID: 35118472

Doi: 10.1101/2022.01.25.477770

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Rapid sequence evolution is associated with genetic incompatibilities in the plastid Clp complex

Authors: Salah E Abdel-Ghany, Lisa M LaManna, Haleakala T Harroun, Pal Maliga, Daniel B Sloan

Journal: Plant Mol Biol

PubMed ID: 35039977

Doi: 10.1007/s11103-022-01241-4

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DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3

Authors: Feng Hu, Ki On Fong, May Pui Lai Cheung, Jessica Aijia Liu, Rui Liang, Tsz Wai Li, Rakesh Sharma, Philip Pun-Ching Ip, Xintao Yang, Martin Cheung

Journal: Adv Sci (Weinh)

PubMed ID: 35088579

Doi: 10.1002/advs.202105226

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Nucleic acid biomarkers to assess graft injury after liver transplantation

Authors: Elissa Bardhi, Jennifer McDaniels, Thomas Rousselle, Daniel G Maluf, Valeria R Mas

Journal: JHEP Rep

PubMed ID: 35243279

Doi: 10.1016/j.jhepr.2022.100439

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The Role of Variants in Neurodevelopmental Diseases: Genotype-Phenotype Association

Authors: Li Shu, Neng Xiao, Jiong Qin, Qi Tian, Yanghui Zhang, Haoxian Li, Jing Liu, Qinrui Li, Weiyue Gu, Pengchao Wang, Hua Wang, Xiao Mao

Journal: Front Mol Neurosci

PubMed ID: 35095415

Doi: 10.3389/fnmol.2021.775479

Products & Services: Mammalian Expression

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma

Authors: Suraya Elfrink, Martin Ter Beest, Luuk Janssen, Marijke Baltissen, Pascal Jansen, Angelique N Kenyon, Raymond Steen, Daynelys de Windt, Philipp Michael Hagemann, Corine Hess, Dick-Johan van Spronsen, Brigiet Hoevenaars, Ellen van der Spek, Zijun Y Xu-Monette, Ken H Young, Charlotte Kaffa, Sander Bervoets, Jolien van Heek, Eva Hesius, Charlotte M de Winde, Michiel Vermeulen, Michiel van den Brand, Blanca Scheijen, Annemiek van Spriel

Journal: Blood Adv

PubMed ID: 35086136

Doi: 10.1182/bloodadvances.2021004366

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Cell membrane-anchored and tumor-targeted IL-12 (attIL12)-T cell therapy for eliminating large and heterogeneous solid tumors

Authors: Jiemiao Hu, Qing Yang, Wendong Zhang, Hongwei Du, Yuhui Chen, Qingnan Zhao, Long Dao, Xueqing Xia, Fowlkes Natalie Wall, Zhongting Zhang, Kris Mahadeo, Richard Gorlick, S Kopetz, Gianpietro Dotti, Shulin Li

Journal: J Immunother Cancer

PubMed ID: 35027427

Doi: 10.1136/jitc-2021-003633

Products & Services: Mammalian Expression

A Bursaphelenchus xylophilus pathogenic protein Bx-FAR-1, as potential control target, mediates the jasmonic acid pathway in pines

Authors: Tong-Yue Wen, Xiao-Qin Wu, Jian-Ren Ye, Yi-Jun Qiu, Lin Rui, Yan Zhang

Journal: Pest Manag Sci

PubMed ID: 35060311

Doi: 10.1002/ps.6805

Products & Services: Recombinant Antibody Expression

Gel-Forming of Self-Assembling Peptides Functionalized with Food Bioactive Motifs Modulate DPP-IV and ACE Inhibitory Activity in Human Intestinal Caco-2 Cells

Authors: Raffaele Pugliese, Martina Bartolomei, Carlotta Bollati, Giovanna Boschin, Anna Arnoldi, Carmen Lammi

Journal: Biomedicines

PubMed ID: 35203539

Doi: 10.3390/biomedicines10020330

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The Role of CD147 in Pathological Cardiac Hypertrophy Is Regulated by Glycosylation

Authors: Fang-Yuan Zhong, Yi-Chao Zhao, Chen-Xu Zhao, Zhi-Chun Gu, Xi-Yuan Lu, Wen-Long Jiang, Ling-Chen Gao, Wen-Li Li, Zi-Han Qin, Heng Ge, Jun Pu

Journal: Oxid Med Cell Longev

PubMed ID: 35096272

Doi: 10.1155/2022/6603296

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Exploring the underlying mechanisms on NaCl-induced reduction in digestibility of myoglobin

Authors: Hui Liu, Qian Li, Shuai Jiang, Miao Zhang, Di Zhao, Kai Shan, Chunbao Li

Journal: Food Chem

PubMed ID: 35077987

Doi: 10.1016/j.foodchem.2022.132183

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A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands

Authors: Micah Steffek, Elizabeth Helgason, Nataliya Popovych, Lionel Rougé, John M Bruning, Ke Sherry Li, Daniel J Burdick, Jianping Cai, Terry Crawford, Jing Xue, Willy Decurtins, Chunlin Fang, Felix Grubers, Michael J Holliday, Allyson Langley, Ann Petersen, Alexander Lee Satz, Aimin Song, Daniel Stoffler, Quentin Strebel, Jeffrey Y K Tom, Nicholas Skelton, Steven T Staben, Moreno Wichert, Melinda M Mulvihill, Erin C Dueber

Journal: Biochemistry

PubMed ID: 34985287

Doi: 10.1021/acs.biochem.1c00682

Products & Services: Gene Synthesis

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss)

Authors: Hui-Xia Yu, Yang Li, Wei-Jia Song, Hui Wang, Hao-Lin Mo, Qiao Liu, Xin-Miao Zhang, Ze-Bin Jiang, Li-Xin Wang

Journal: Fish Physiol Biochem

PubMed ID: 35098384

Doi: 10.1007/s10695-021-01033-5

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The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis

Authors: Jihui Zhang, Hongwei Lei, Xiu Li

Journal: Bioengineered

PubMed ID: 34965184

Doi: 10.1080/21655979.2021.2001911

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Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma

Authors: Huaijun Wang, Zhongqian Hu, Uday Kumar Sukumar, Rajendran Jc Bose, Arsenii Telichko, Jeremy J Dahl, Ramasamy Paulmurugan

Journal: Nanotheranostics

PubMed ID: 34976581

Doi: 10.7150/ntno.63320

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Sterility of Sustained-release Buprenorphine

Authors: Shraddha I Cantara, Crystal Gergye, Vanessa K Lee, Michael Huerkamp

Journal: J Am Assoc Lab Anim Sci

PubMed ID: 35082006

Doi: 10.30802/AALAS-JAALAS-21-000105

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ADAM17 regulates the proliferation and extracellular matrix of keloid fibroblasts by mediating the EGFR/ERK signaling pathway

Authors: Xin Le, You-Fen Fan

Journal: J Plast Surg Hand Surg

PubMed ID: 34978504

Doi: 10.1080/2000656X.2021.2017944

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Blue-light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection

Authors: Shaista Naqvi, Qin He, Franziska Trusch, Huishan Qiu, Jasmine Pham, Qingguo Sun, John M Christie, Eleanor M Gilroy, Paul R J Birch

Journal: New Phytol

PubMed ID: 34923631

Doi: 10.1111/nph.17929

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Investigation of putative antimicrobial peptides in Carassius gibel, revealing a practical approach to screening antimicrobials

Authors: Yujun Zhang, Ping Deng, Caijiao Dai, Mengke Wu, Xueqin Liu, Lijuan Li, Xiaoyi Pan, Junfa Yuan

Journal: Fish Shellfish Immunol

PubMed ID: 34990806

Doi: 10.1016/j.fsi.2021.12.050

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Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells

Journal: Stem Cells Int

PubMed ID: 35047041

Doi: 10.1155/2022/4930932

Products & Services: ORF cDNA Clones/MolecularCloud

Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase

Authors: Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza, Ikechukwu Achilonu

Journal: Protein J

PubMed ID: 35083643

Doi: 10.1007/s10930-021-10037-2

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Experimental Periodontitis Deteriorated Atherosclerosis Associated With Trimethylamine N-Oxide Metabolism in Mice

Authors: Lingling Xiao, Lingyan Huang, Xin Zhou, Dan Zhao, Yan Wang, Haiyan Min, Shiyu Song, Weibin Sun, Qian Gao, Qingang Hu, Sijing Xie

Journal: Front Cell Infect Microbiol

PubMed ID: 35118014

Doi: 10.3389/fcimb.2021.820535

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Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening

Authors: Meghan J O'Melia, Adriana Mulero-Russe, Jihoon Kim, Alyssa Pybus, Deborah DeRyckere, Levi Wood, Douglas K Graham, Edward Botchwey, Andrés J García, Susan N Thomas

Journal: Adv Mater

PubMed ID: 34989049

Doi: 10.1002/adma.202108084

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RIPPA: Identification of MHC-II Binding Peptides from Antigen Using a Yeast Display-Based Approach

Authors: Rongzeng Liu, Wei Jiang, Ying Li, Elizabeth D Mellins

Journal: Curr Protoc

PubMed ID: 35041265

Doi: 10.1002/cpz1.350

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Antigenic and immunogenic properties of recombinant proteins consisting of two immunodominant African swine fever virus proteins fused with bacterial lipoprotein OprI

Authors: Guanglei Zhang, Wei Liu, Zhan Gao, Yanyan Chang, Sicheng Yang, Qian Peng, Sudan Ge, Bijing Kang, Junjun Shao, Huiyun Chang

Journal: Virol J

PubMed ID: 35062983

Doi: 10.1186/s12985-022-01747-9

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Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study

Authors: Layaly Shkair, Ekaterina Evgenevna Garanina, Ekaterina Vladimirovna Martynova, Alena Igorevna Kolesnikova, Svetlana Sergeevna Arkhipova, Angelina Andreevna Titova, Albert Anatolevich Rizvanov, Svetlana Francevna Khaiboullina

Journal: Pharmaceutics

PubMed ID: 35056989

Doi: 10.3390/pharmaceutics14010093

Products & Services: Plasmid DNA Preparation PCR Cloning and Subcloning

Improving one-step scarless genome editing in by combining co-CRISPR selection with sgRNA target site masking

Authors: Katharina J Götze, Achmed Mrestani, Paula Beckmann, Knut Krohn, Diana Le Duc, Akhil Velluva, Mathias A Böhme, Manfred Heckmann, Rami Abou Jamra, Johannes R Lemke, Hendrik Bläker, Nicole Scholz, Dmitrij Ljaschenko, Tobias Langenhan

Journal: Biol Methods Protoc

PubMed ID: 35087953

Doi: 10.1093/biomethods/bpac003

Products & Services: Plasmid DNA Preparation

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities

Authors: Raffaele Iennaco, Giulio Formenti, Camilla Trovesi, Riccardo Lorenzo Rossi, Chiara Zuccato, Tiziana Lischetti, Vittoria Dickinson Bocchi, Andrea Scolz, Cristina Martínez-Labarga, Olga Rickards, Michela Pacifico, Angelica Crottini, Anders Pape Møller, Richard Zhenghuan Chen, Thomas Francis Vogt, Giulio Pavesi, David Stephen Horner, Nicola Saino, Elena Cattaneo

Journal: Cell Death Differ

PubMed ID: 34974533

Doi: 10.1038/s41418-021-00914-9

Products & Services: PCR Cloning and Subcloning

Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids

Authors: Icaro Putinhon Caruso, Vitor Dos Santos Almeida, Mariana Juliani do Amaral, Guilherme Caldas de Andrade, Gabriela Rocha de Araújo, Talita Stelling de Araújo, Jéssica Moreira de Azevedo, Glauce Moreno Barbosa, Leonardo Bartkevihi, Peter Reis Bezerra, Katia Maria Dos Santos Cabral, Isabella Otênio de Lourenço, Clara L F Malizia-Motta, Aline de Luna Marques, Nathane Cunha Mebus-Antunes, Thais Cristtina Neves-Martins, Jéssica Maróstica de Sá, Karoline Sanches, Marcos Caique Santana-Silva, Ariana Azevedo Vasconcelos, Marcius da Silva Almeida, Gisele Cardoso de Amorim, Cristiane Dinis Anobom, Andrea T Da Poian, Francisco Gomes-Neto, Anderson S Pinheiro, Fabio C L Almeida

Journal: Int J Biol Macromol

PubMed ID: 35077748

Doi: 10.1016/j.ijbiomac.2022.01.121

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A Palette of Fluorescent A42 Peptides Labelled at a Range of Surface-Exposed Sites

Authors: Dev Thacker, Mara Bless, Mohammad Barghouth, Enming Zhang, Sara Linse

Journal: Int J Mol Sci

PubMed ID: 35163577

Doi: 10.3390/ijms23031655

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Three Specific Potential Epitopes That Could Be Recognized by T Cells of Convalescent COVID-19 Patients Were Identified From Spike Protein

Authors: Yunwen Zhang, Zhengrong Yang, Mingyuan Tang, Hao Li, Tian Tang, Guilian Li, Yifan Zhong, Xiaomin Zhang, Xiaohui Wang, Chuan Wang

Journal: Front Immunol

PubMed ID: 35154095

Doi: 10.3389/fimmu.2022.752622

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Single-conformation spectroscopy of cold, protonated PG-containing peptides: switching β-turn types and formation of a sequential type II/II' double β-turn

Authors: John T Lawler, Christopher P Harrilal, Andrew F DeBlase, Edwin L Sibert, Scott A McLuckey, Timothy S Zwier

Journal: Phys Chem Chem Phys

PubMed ID: 35019911

Doi: 10.1039/d1cp04852j

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The H, N and C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1

Authors: Courtney N Johnson, Xiaoping Xu, Stephen P Holloway, David S Libich

Journal: Biomol NMR Assign

PubMed ID: 34994941

Doi: 10.1007/s12104-021-10061-4

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