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A mosquito AgTRIO monoclonal antibody reduces early infection of mice
Authors: Yu-Min Chuang, Xu-Dong Tang, Erol Fikrig
Journal: Infect Immun
PubMed ID: 34724388
Doi: 10.1128/IAI.00359-21
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Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization
Authors: Nikolas Friedrich, Emanuel Stiegeler, Matthias Glögl, Thomas Lemmin, Simon Hansen, Claus Kadelka, Yufan Wu, Patrick Ernst, Liridona Maliqi, Caio Foulkes, Mylène Morin, Mustafa Eroglu, Thomas Liechti, Branislav Ivan, Thomas Reinberg, Jonas V Schaefer, Umut Karakus, Stephan Ursprung, Axel Mann, Peter Rusert, Roger D Kouyos, John A Robinson, Huldrych F Günthard, Andreas Plückthun, Alexandra Trkola
Journal: Nat Commun
PubMed ID: 34795280
Doi: 10.1038/s41467-021-27075-0
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Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation
Authors: Hengjun Cui, Andreas U Müller, Marc Leibundgut, Jiawen Tian, Nenad Ban, Eilika Weber-Ban
Journal: Nat Commun
PubMed ID: 34789727
Doi: 10.1038/s41467-021-26848-x
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Tryptophan Side-Chain Oxidase Enzyme Suppresses Hepatocellular Carcinoma Growth through Degradation of Tryptophan
Authors: Yang Ai, Ben Wang, Shuai Xiao, Sang Luo, Yefu Wang
Journal: Int J Mol Sci
PubMed ID: 34830310
Doi: 10.3390/ijms222212428
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Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination
Authors: Wooseob Kim, Julian Q Zhou, Alexandria J Sturtz, Stephen C Horvath, Aaron J Schmitz, Tingting Lei, Elizaveta Kalaidina, Mahima Thapa, Wafaa B Alsoussi, Alem Haile, Michael K Klebert, Teresa Suessen, Luis Parra-Rodriguez, Philip A Mudd, William D Middleton, Sharlene A Teefey, Iskra Pusic, Jane A O'Halloran, Rachel M Presti, Jackson S Turner, Ali H Ellebedy
Journal: biorxiv
PubMed ID: 34751268
Doi: 10.1101/2021.10.31.466651
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MiR-702-3p inhibits the inflammatory injury in septic H9c2 cells by regulating NOD1
Authors: Chun Liu, Yang Yang, Guiwen Liang, Aixian Zhang, Feng Xu
Journal: Transpl Immunol
PubMed ID: 34774740
Doi: 10.1016/j.trim.2021.101493
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T cell receptor therapy targeting mutant capicua transcriptional repressor in experimental gliomas
Authors: Michael Kilian, Mirco Friedrich, Khwab Sanghvi, Edward Green, Stefan Pusch, Daisuke Kawauchi, Martin Löwer, Jana K Sonner, Christopher Krämer, Julia Zaman, Stefanie Jung, Michael O Breckwoldt, Gerald Willimksy, Stefan B Eichmüller, Andreas von Deimling, Wolfgang Wick, Felix Sahm, Michael Platten, Lukas Bunse
Journal: Clin Cancer Res
PubMed ID: 34782365
Doi: 10.1158/1078-0432.CCR-21-1881
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Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus
Authors: Ebru Destan, Busra Yuksel, Bradley B Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A Francis, Hasan DeMirci
Journal: Sci Rep
PubMed ID: 34819551
Doi: 10.1038/s41598-021-02180-8
Products & Services: Codon Optimization   
Proteolytic processing of plant proteins by potyvirus NIa proteases
Authors: Huogen Xiao, Etienne Lord, Hélène Sanfaçon
Journal: J Virol
PubMed ID: 34757836
Doi: 10.1128/JVI.01444-21
Products & Services: Codon Optimization   
Structure of native HIV-1 cores and their interactions with IP6 and CypA
Authors: Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till Böcking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang
Journal: Sci Adv
PubMed ID: 34797722
Doi: 10.1126/sciadv.abj5715
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Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity
Authors: Jonathan P Renn, Justin Y A Doritchamou, Bergeline C Nguemwo Tentokam, Robert D Morrison, Matthew V Cowles, Martin Burkhardt, Rui Ma, Niraj H Tolia, Michal Fried, Patrick E Duffy
Journal: Commun Biol
PubMed ID: 34799664
Doi: 10.1038/s42003-021-02787-7
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Multi-Antigen Outer Membrane Vesicle Engineering to Develop Polyvalent Vaccines: The Case
Authors: Enrico König, Assunta Gagliardi, Ilary Riedmiller, Chiara Andretta, Michele Tomasi, Carmela Irene, Luca Frattini, Ilaria Zanella, Francesco Berti, Alberto Grandi, Elena Caproni, Laura Fantappiè, Guido Grandi
Journal: Front Immunol
PubMed ID: 34819933
Doi: 10.3389/fimmu.2021.752168
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Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy
Authors: Jun Zheng, Xi Chen, Qiang Liu, Guisheng Zhong, Min Zhuang
Journal: J Cell Biol
PubMed ID: 34747980
Doi: 10.1083/jcb.202103156
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Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice
Authors: Cherng-Shyang Chang, Yi-Chu Liao, Chih-Ting Huang, Chiao-Mei Lin, Chantal Hoi Yin Cheung, Jhen-Wei Ruan, Wen-Hsuan Yu, Yi-Ting Tsai, I-Jung Lin, Chien-Hsun Huang, Jong-Shian Liou, Ya-Hsien Chou, Hung-Jen Chien, Hsiao-Li Chuang, Hsueh-Fen Juan, Hsuan-Cheng Huang, Hong-Lin Chan, Yu-Chieh Liao, Shiue-Cheng Tang, Yu-Wen Su, Tse-Hua Tan, Andreas J Bäumler, Cheng-Yuan Kao
Journal: Cell Rep
PubMed ID: 34818535
Doi: 10.1016/j.celrep.2021.110016
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Structures of the Human SPAK and OSR1 Conserved C-Terminal (CCT) Domains*
Authors: Karen T Elvers, Magdalena Lipka-Lloyd, Rebecca C Trueman, Benjamin D Bax, Youcef Mehellou
Journal: Chembiochem
PubMed ID: 34726826
Doi: 10.1002/cbic.202100441
Products & Services: Gene Synthesis   
Pharmacological modulation of the cAMP signaling of two isoforms of melanocortin-3 receptor by melanocortin receptor accessory proteins in the tetrapod Xenopus laevis
Authors: Ying Xu, Lei Li, Jihong Zheng, Meng Wang, Bopei Jiang, Yue Zhai, Liumei Lu, Cong Zhang, Zhe Kuang, Xiaomei Yang, Li-Na Jin, Gufa Lin, Chao Zhang
Journal: Endocr Connect
PubMed ID: 34678757
Doi: 10.1530/EC-21-0179
Products & Services: Recombinant Proteins   
Structure of Rift Valley fever virus RNA-dependent RNA polymerase
Authors: Xue Wang, Cuixia Hu, Wei Ye, Jia Wang, Xiaofei Dong, Jie Xu, Xiaorong Li, Manfeng Zhang, Hongyun Lu, Fanglin Zhang, Wei Wu, Shaodong Dai, Hong-Wei Wang, Zhongzhou Chen
Journal: J Virol
PubMed ID: 34787453
Doi: 10.1128/JVI.01713-21
Products & Services: Proteins, Expression, Isolation and Analysis   
Alpha adaptins show isoform-specific association with neurofibrillary tangles in Alzheimer's disease
Authors: Sukanya Srinivasan, Jozsef Gal, Adam Bachstetter, Peter T Nelson
Journal: Neuropathol Appl Neurobiol
PubMed ID: 34820873
Doi: 10.1111/nan.12776
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ABCC2 is a functional receptor of Bacillus thuringiensis Cry1Ca in Spodoptera litura
Authors: Xue Yao, Chen Liu, Yunpeng Duan, Shiheng An, Jizhen Wei, Gemei Liang
Journal: Int J Biol Macromol
PubMed ID: 34861271
Doi: 10.1016/j.ijbiomac.2021.11.174
Products & Services: Recombinant Proteins   
Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides
Authors: Maria Carmina Scala, Simone Di Micco, Delia Lanzillotta, Simona Musella, Veronica Di Sarno, Barbara Parrino, Stella Maria Casciofierro, Giuseppe Bifulco, Francesco Trapasso, Pietro Campiglia, Marina Sala
Journal: Front Mol Biosci
PubMed ID: 34901149
Doi: 10.3389/fmolb.2021.715263
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Molecular characterization of substrate-induced ubiquitin transfer by UBR7-PHD finger, a newly identified histone H2BK120 ubiquitin ligase
Authors: Anirban Dasgupta, Payel Mondal, Sambit Dalui, Chandrima Das, Siddhartha Roy
Journal: FEBS J
PubMed ID: 34739193
Doi: 10.1111/febs.16262
Products & Services: Recombinant Proteins   
Gamma delta TCR anti-CD3 bispecific molecules (GABs) as novel immunotherapeutic compounds
Authors: Eline van Diest, Patricia Hernández López, Angelo D Meringa, Anna Vyborova, Froso Karaiskaki, Sabine Heijhuurs, Jan Gumathi Bormin, Sanne van Dooremalen, Mara J T Nicolasen, Lucrezia C D E Gatti, Inez Johanna, Trudy Straetemans, Zsolt Sebestyén, Dennis X Beringer, Jürgen Kuball
Journal: J Immunother Cancer
PubMed ID: 34815357
Doi: 10.1136/jitc-2021-003850
Products & Services: Peptide Synthesis   
The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid
Authors: Anton A Stepnov, Idd A Christensen, Zarah Forsberg, Finn L Aachmann, Gaston Courtade, Vincent G H Eijsink
Journal: FEBS Lett
PubMed ID: 34845720
Doi: 10.1002/1873-3468.14246
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Structural characterization of the porcine adeno-associated virus Po1 capsid protein binding to the nuclear trafficking protein importin alpha
Authors: Mikayla Hoad, Justin A Roby, Jade K Forwood
Journal: FEBS Lett
PubMed ID: 34661283
Doi: 10.1002/1873-3468.14209
Products & Services: Bacterial Expression   
A simple PCR-RFLP method for identification and detection of medicinal toad and its crude drug even with serious degradation of DNA
Authors: Jiao Liu, Xinyi Shao, Ziying Zhou, Miao Lei, Mingyu Xia, Dong Wang
Journal: J Pharm Biomed Anal
PubMed ID: 34864355
Doi: 10.1016/j.jpba.2021.114495
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1,800 MHz Radiofrequency Electromagnetic Irradiation Impairs Neurite Outgrowth With a Decrease in Rap1-GTP in Primary Mouse Hippocampal Neurons and Neuro2a Cells
Authors: Yanqi Li, Ping Deng, Chunhai Chen, Qinlong Ma, Huifeng Pi, Mindi He, Yonghui Lu, Peng Gao, Chao Zhou, Zhixin He, Yanwen Zhang, Zhengping Yu, Lei Zhang
Journal: Front Public Health
PubMed ID: 34881219
Doi: 10.3389/fpubh.2021.771508
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Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
Authors: Cristina Gil-Cruz, Christian Perez-Shibayama, Angelina De Martin, Francesca Ronchi, Katrien van der Borght, Rebekka Niederer, Lucas Onder, Mechthild Lütge, Mario Novkovic, Veronika Nindl, Gustavo Ramos, Markus Arnoldini, Emma M C Slack, Valérie Boivin-Jahns, Roland Jahns, Madeleine Wyss, Catherine Mooser, Bart N Lambrecht, Micha T Maeder, Hans Rickli, Lukas Flatz, Urs Eriksson, Markus B Geuking, Kathy D McCoy, Burkhard Ludewig
Journal: Science
PubMed ID: 31727837
Doi: 10.1126/science.aav3487
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Two energy barriers and a transient intermediate state determine the unfolding and folding dynamics of cold shock protein
Authors: Haiyan Hong, Zilong Guo, Hao Sun , Ping Yu , Huanhuan Su , Xuening Ma & Hu Chen
Journal: Communications Chemistry
Doi: doi.org/10.1038/s42004-021-00592-1
Products & Services: Gene Synthesis   
Performance Evaluation of the BZ COVID-19 Neutralizing Antibody Test for the Culture-Free and Rapid Detection of SARS-CoV-2 Neutralizing Antibodies
Authors: Bo Kyeung Jung, Jung Yoon, Joon-Yong Bae, Jeonghun Kim, Man-Seong Park, Suk Yong Lee, Chae Seung Lim
Journal: Diagnostics (Basel)
PubMed ID: 34943430
Doi: 10.3390/diagnostics11122193
Products & Services: Protein Reagents and Products   
Picomolar inhibition of SARS-CoV-2 variants of concern by an engineered ACE2-IgG4-Fc fusion protein
Authors: Hristo L Svilenov, Julia Sacherl, Alwin Reiter, Lisa S Wolff, Cho-Chin Cheng, Marcel Stern, Vincent Grass, Martin Feuerherd, Frank-Peter Wachs, Nicole Simonavicius, Susanne Pippig, Florian Wolschin, Oliver T Keppler, Johannes Buchner, Carsten Brockmeyer, Ulrike Protzer
Journal: Antiviral Res
PubMed ID: 34774603
Doi: 10.1016/j.antiviral.2021.105197
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Kinetics of anti-SARS-CoV-2 neutralizing antibodies development after BNT162b2 vaccination in patients with amyloidosis and the impact of therapy
Authors: Efstathios Kastritis, Evangelos Terpos, Zoi Evangelakou, Foteini Theodorakakou, Despina Fotiou, Maria S Manola, Despoina D Gianniou, Tina Bagratuni, Nikolaos Kanellias, Magdalini Migkou, Maria Gavriatopoulou, Ioannis P Trougakos, Meletios A Dimopoulos
Journal: Am J Hematol
PubMed ID: 34778995
Doi: 10.1002/ajh.26406
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Backbone H, N, and C resonance assignments of the non-structural protein NS2B of Zika virus
Authors: Beatriz Rosa Penna, Danielle Maria P de Oliveira, Cristiane Dinis Anobom, Ana Paula Valente
Journal: Biomol NMR Assign
PubMed ID: 34817802
Doi: 10.1007/s12104-021-10055-2
Products & Services: Codon Optimization   
Cholecystokinin-B Receptor-Targeted Nanoparticle for Imaging and Detection of Precancerous Lesions in the Pancreas
Authors: Jill P Smith, Hong Cao, Elijah F Edmondson, Siva Sai Krishna Dasa, Stephan T Stern
Journal: Biomolecules
PubMed ID: 34944412
Doi: 10.3390/biom11121766
Products & Services: Catalog Peptides   
The concentration of brain homogenates with the Amicon Ultra Centrifugal filters
Authors: Joshua Yang, Rachita K Sumbria
Journal: MethodsX
PubMed ID: 35004217
Doi: 10.1016/j.mex.2021.101584
Products & Services: Catalog Antibody   
Biochemical basis for an interaction between SNX27 and the flexible SNX1 N-terminus
Authors: Mintu Chandra, Brett M Collins, Lauren P Jackson
Journal: Adv Biol Regul
PubMed ID: 34866035
Doi: 10.1016/j.jbior.2021.100842
Products & Services: Catalog Peptides   
Endotoxin contamination in commercially available Cas9 proteins potentially induces T-cell mediated responses
Authors: Vijaya L Simhadri, Joseph R McGill, Zuben E Sauna
Journal: Gene Ther
PubMed ID: 34744169
Doi: 10.1038/s41434-021-00301-6
Products & Services: Proteins, Expression, Isolation and Analysis   
JNK/Itch Axis Mediates the Lipopolysaccharide-Induced Ubiquitin-Proteasome-Dependent Degradation of Ferritin Light Chain in Murine Macrophage Cells
Authors: Shufen He, Jianqi Xue, Pengxiu Cao, Jianyuan Hou, Yan Cui, Jing Chang, Liying Huang, Yu Han, Xianglin Duan, Ke Tan, Yumei Fan
Journal: Inflammation
PubMed ID: 34837126
Doi: 10.1007/s10753-021-01603-y
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Characterization of Anti-Ana o 3 Monoclonal Antibodies and Their Application in Comparing Brazilian Cashew Cultivars
Authors: Christopher P Mattison, Barry Vant-Hull, Ana Cecilia Ribeiro de Castro, Heidi J Chial, Yvette Bren-Mattison, Peter J Bechtel, Edy Sousa de Brito
Journal: Antibodies (Basel)
PubMed ID: 34939998
Doi: 10.3390/antib10040046
Products & Services: DNA Sequencing   
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy
Authors: Sheng-Li Ming , Shuang Zhang , Qi Wang , Lei Zeng , Lu-Yu Zhou , Meng-Di Wang , Ying-Xian Ma , Li-Qiang Han , Kai Zhong , He-Shui Zhu , Yi-Lin Bai , Guo-Yu Yang , Jiang Wang , Bei-Bei Chu
Journal: Autophagy
PubMed ID: 34822318
Doi: 10.1080/15548627.2021.2002101
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Novel xylan-degrading enzymes from polysaccharide utilizing loci of Prevotella copri DSM18205
Authors: Javier A Linares-Pastén , Johan Sebastian Hero , José Horacio Pisa , Cristina Teixeira , Margareta Nyman , Patrick Adlercreutz , M Alejandra Martinez , Eva Nordberg Karlsson
Journal: Glycobiology
PubMed ID: 34142143
Doi: 10.1093/glycob/cwab056
Products & Services: Gene Synthesis   
Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers
Authors: Orly Avraham, Edward A Bayer, Oded Livnah
Journal: FEBS J
PubMed ID: 34726340
Doi: 10.1111/febs.16259
Products & Services: Codon Optimization   
Phylogenetic Analysis of the Plant U2 snRNP Auxiliary Factor Large Subunit A Gene Family in Response to Developmental Cues and Environmental Stimuli
Authors: Shuai Lu, Cong Gao, Yongzhou Wang, Yingying He, Junrong Du, Moxian Chen, Hua Zhao, Hui Fang, Baohua Wang, Yunying Cao
Journal: Front Plant Sci
PubMed ID: 34868124
Doi: 10.3389/fpls.2021.739671
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Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants
Authors: Matthew McCallum, Alexandra C Walls, Kaitlin R Sprouse, John E Bowen, Laura E Rosen, Ha V Dang, Anna De Marco, Nicholas Franko, Sasha W Tilles, Jennifer Logue, Marcos C Miranda, Margaret Ahlrichs, Lauren Carter, Gyorgy Snell, Matteo Samuele Pizzuto, Helen Y Chu, Wesley C Van Voorhis, Davide Corti, David Veesler
Journal: Science
PubMed ID: 34751595
Doi: 10.1126/science.abl8506
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Immune Responses to a Single Dose of the AZD1222/Covishield Vaccine at 16 Weeks in Individuals in Sri Lanka
Authors: Chandima Jeewandara, Dinuka Guruge, Pradeep Darshana Pushpakumara, Achala Kamaladasa, Inoka Sepali Aberathna, Shyrar Tanussiya Ramu, Banuri Gunasekera, Ayesha Wijesinghe, Osanda Dissanayake, Heshan Kuruppu, Thushali Ranasinghe, Deshni Jayathilaka, Shashika Dayarathna, Dinithi Ekanayake, Jeewantha Jayamali, Nayanathara Gamalath, Anushika Mudunkotiwa, Gayasha Somathilake, Madhushika Dissanayake, Michael Harvie, Thashmi Nimasha, Deshan Madusanka, Tibutius Jayadas, Ruwan Wijayamuni, Lisa Schimanski, Pramila Rijal, Tiong K Tan, Alain Townsend, Graham S Ogg, Gathsaurie Neelika Malavige
Journal: J Immunol
PubMed ID: 34750205
Doi: 10.4049/jimmunol.2100762
Products & Services: Recombinant Antibody Expression   
α-Klotho released from HK-2 cells inhibits osteogenic differentiation of renal interstitial fibroblasts by inactivating the Wnt-β-catenin pathway
Authors: Zewu Zhu, Shuhao Ruan, Yingcheng Jiang, Fang Huang, Weiping Xia, Jinbo Chen, Yu Cui, Cheng He, Feng Zeng, Yang Li, Zhiyong Chen, Hequn Chen
Journal: Cell Mol Life Sci
PubMed ID: 34724098
Doi: 10.1007/s00018-021-03972-x
Products & Services: Proteins, Expression, Isolation and Analysis   
Hydrolytically Stable Maleimide-End-Functionalized Polymers for Site-Specific Protein Conjugation
Authors: Thaiesha A Wright, Monica Sharfin Rahman, Camaryn Bennett, Madolynn R Johnson, Henry Fischesser, Natasha Ram, Amoni Tyler, Richard C Page, Dominik Konkolewicz
Journal: Bioconjug Chem
PubMed ID: 34730954
Doi: 10.1021/acs.bioconjchem.1c00487
Products & Services: Plasmid DNA Preparation   
LDH nanoparticle adjuvant subunit vaccine induces an effective immune response for porcine epidemic diarrhea virus
Authors: Danyi Shi, Baochao Fan, Bing Sun, Jinzhu Zhou, Yongxiang Zhao, Rongli Guo, Zengjun Ma, Tao Song, Huiying Fan, Jizong Li, Li Li, Bin Li
Journal: Virology
PubMed ID: 34739917
Doi: 10.1016/j.virol.2021.10.010
Products & Services: Plasmid DNA Preparation   
Polyactin A and CpG enhance inactivated Pseudomonas plecoglossicida vaccine potency in large yellow croaker (Larimichthys crocea)
Authors: Wenwen Wang, Wei Wang, Wenjun Xu, Qin Liu, Yuanxing Zhang, Xiaohong Liu
Journal: Fish Shellfish Immunol
PubMed ID: 34780977
Doi: 10.1016/j.fsi.2021.11.008
Products & Services: Plasmid DNA Preparation   
STING inhibition accelerates the bone healing process while enhancing type H vessel formation
Authors: Xiaojun Chen, Wenxin He, Mengzhe Sun, Yingjie Yan, Yichuan Pang, Gang Chai
Journal: FASEB J
PubMed ID: 34694030
Doi: 10.1096/fj.202100069RR
Products & Services: Nucleic Acid Purification & Analysis   
Structural basis and mechanism of activation of two different families of G proteins by the same GPCR
Authors: Kamela O Alegre, Navid Paknejad, Minfei Su, Jian-Shu Lou, Jianyun Huang, Kelsey D Jordan, Edward T Eng, Joel R Meyerson, Richard K Hite, Xin-Yun Huang
Journal: Nat Struct Mol Biol
PubMed ID: 34759376
Doi: 10.1038/s41594-021-00679-2
Products & Services: Mutant Libraries   
Circular RNA hsa_circ_0043278 inhibits breast cancer progression via the miR-455-3p/EI24 signalling pathway
Authors: Yue Shi, Chong Liu
Journal: BMC Cancer
PubMed ID: 34800978
Doi: 10.1186/s12885-021-08989-w
Products & Services: Mutant Libraries   
Mapping enzyme catalysis with metabolic biosensing
Authors: Linfeng Xu, Kai-Chun Chang, Emory M Payne, Cyrus Modavi, Leqian Liu, Claire M Palmer, Nannan Tao, Hal S Alper, Robert T Kennedy, Dale S Cornett, Adam R Abate
Journal: Nat Commun
PubMed ID: 34815408
Doi: 10.1038/s41467-021-27185-9
Products & Services: Mutagenesis Services   
SpSR-B2 functions as a potential pattern recognition receptor involved in antiviral and antibacterial immune responses of mud crab Scylla paramamosain
Authors: Jian Zhou, Jun-Fang Zhou, Yue Wang, Guang-Peng Feng, Wen-Hong Fang, Wei Kang, Ling-Bo Ma, Xin-Cang Li
Journal: Int J Biol Macromol
PubMed ID: 34780895
Doi: 10.1016/j.ijbiomac.2021.11.048
Products & Services: Monoclonal Antibody Services   
Photoredox-Catalyzed Decarboxylative -Terminal Differentiation for Bulk- and Single-Molecule Proteomics
Authors: Le Zhang, Brendan M Floyd, Maheshwerreddy Chilamari, James Mapes, Jagannath Swaminathan, Steven Bloom, Edward M Marcotte, Eric V Anslyn
Journal: ACS Chem Biol
PubMed ID: 34734691
Doi: 10.1021/acschembio.1c00631
Products & Services: Mammalian Expression   
Elevated Fab glycosylation of anti-hinge antibodies
Authors: J Koers, Nil Derksen, Wjj Falkenburg, P Ooijevaar-de Heer, M T Nurmohamed, G J Wolbink, T Rispens
Journal: Scand J Rheumatol
PubMed ID: 34726124
Doi: 10.1080/03009742.2021.1986959
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Using recombinant adhesive proteins as durable and green flame-retardant coatings
Authors: Weng I Leong, Owen Lok In Lo, Fong Tin Cheng, Wai Man Cheong, Leo Chi U Seak
Journal: Synth Syst Biotechnol
PubMed ID: 34786512
Doi: 10.1016/j.synbio.2021.10.005
Products & Services: GenParts™ DNA Fragments   
Structure and Function of a Dual Reductase-Dehydratase Enzyme System Involved in -Terphenyl Biosynthesis
Authors: Jonathan A Clinger, Yinan Zhang, Yang Liu, Mitchell D Miller, Ronnie E Hall, Steven G Van Lanen, George N Phillips, Jon S Thorson, Sherif I Elshahawi
Journal: ACS Chem Biol
PubMed ID: 34763417
Doi: 10.1021/acschembio.1c00701
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Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp YS-1 and characterization of two initial degrading esterases
Authors: Na Shang, Lingling Chen, Minggen Cheng, Yanning Tian, Xing Huang
Journal: Sci Total Environ
PubMed ID: 34742792
Doi: 10.1016/j.scitotenv.2021.151357
Products & Services: DNA Sequencing   
Structural and functional insights into the spike protein mutations of emerging SARS-CoV-2 variants
Authors: Deepali Gupta, Priyanka Sharma, Mandeep Singh, Mukesh Kumar, A S Ethayathulla, Punit Kaur
Journal: Cell Mol Life Sci
PubMed ID: 34731254
Doi: 10.1007/s00018-021-04008-0
Products & Services: DNA Sequencing   
Prokaryotic expression, evaluation, and prediction of the structure and function of the ecarin metalloproteinase domain
Authors: Nasrin Mohammadi, Mojgan Bandehpour, Fattah Sotoodehnejadnematalahi, Bahram Kazemi
Journal: Proteins
PubMed ID: 34739152
Doi: 10.1002/prot.26275
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African Swine Fever Virus pE199L Induces Mitochondrial-Dependent Apoptosis
Authors: Tingting Li, Gaihong Zhao, Taoqing Zhang, Zhaoxia Zhang, Xin Chen, Jie Song, Xiao Wang, Jiangnan Li, Li Huang, Lili Wen, Changyao Li, Dongming Zhao, Xijun He, Zhigao Bu, Jun Zheng, Changjiang Weng
Journal: Viruses
PubMed ID: 34835046
Doi: 10.3390/v13112240
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5' Half of specific tRNAs feeds back to promote corresponding tRNA gene transcription in vertebrate embryos
Authors: Luxi Chen, Wei Xu, Kunpeng Liu, Zheng Jiang, Yang Han, Hongbin Jin, Lin Zhang, Weimin Shen, Shunji Jia, Qianwen Sun, Anming Meng
Journal: Sci Adv
PubMed ID: 34797706
Doi: 10.1126/sciadv.abh0494
Products & Services: Custom Vector Construction   
Cyclophilin A is a key positive and negative feedback regulator within interleukin-6 trans-signaling pathway
Authors: Xiaohan Luan, Wenxian Yang, Xiaoyuan Bai, Heqiao Li, Huizi Li, Wenhui Fan, He Zhang, Wenjun Liu, Lei Sun
Journal: FASEB J
PubMed ID: 34606626
Doi: 10.1096/fj.202101044RRR
Products & Services: Custom Vector Construction   
A structural feature of Dda helicase which enhances displacement of streptavidin and trp repressor from DNA
Authors: Alicia K Byrd, Emory G Malone, Lindsey Hazeslip, Maroof Khan Zafar, David K Harrison, Matthew D Thompson, Jun Gao, Senthil K Perumal, John C Marecki, Kevin D Raney
Journal: Protein Sci
PubMed ID: 34761452
Doi: 10.1002/pro.4232
Products & Services: Codon Optimization   
Identification and Characterization of Antigen-Specific CD8 T Cells Using Surface-Trapped TNF-α and Single-Cell Sequencing
Authors: Shaheed Abdulhaqq, Abigail B Ventura, Jason S Reed, Arman A Bashirova, Katherine B Bateman, Eric McDonald, Helen L Wu, Justin M Greene, John B Schell, David Morrow, Karin Wisskirchen, Jeffrey N Martin, Steven G Deeks, Mary Carrington, Ulrike Protzer, Klaus Früh, Scott G Hansen, Louis J Picker, Jonah B Sacha, Benjamin N Bimber
Journal: J Immunol
PubMed ID: 34810222
Doi: 10.4049/jimmunol.2100535
Products & Services: Catalog Peptides   
The Ionic Selectivity of Lysenin Channels in Open and Sub-Conducting States
Authors: Andrew Bogard, Pangaea W Finn, Fulton McKinney, Ilinca M Flacau, Aviana R Smith, Rosey Whiting, Daniel Fologea
Journal: Membranes (Basel)
PubMed ID: 34832126
Doi: 10.3390/membranes11110897
Products & Services: Catalog Antibody   
SARS-CoV-2 Infection of Rhesus Macaques Treated Early with Human COVID-19 Convalescent Plasma
Authors: Jesse D Deere, Timothy D Carroll, Joseph Dutra, Linda Fritts, Rebecca Lee Sammak, JoAnn L Yee, Katherine J Olstad, J Rachel Reader, Amy Kistler, Jack Kamm, Clara Di Germanio, Yashavanth Shaan Lakshmanappa, Sonny R Elizaldi, Jamin W Roh, Graham Simmons, Jennifer Watanabe, Rachel E Pollard, Jodie Usachenko, Ramya Immareddy, Brian A Schmidt, Shelby L O'Connor, Joseph DeRisi, Michael P Busch, Smita S Iyer, Koen K A Van Rompay, Dennis J Hartigan-O'Connor, Christopher J Miller
Journal: Microbiol Spectr
PubMed ID: 34817208
Doi: 10.1128/Spectrum.01397-21
Products & Services: Recombinant Proteins   
Retinol-Binding Protein 4 Promotes Cardiac Injury After Myocardial Infarction Via Inducing Cardiomyocyte Pyroptosis Through an Interaction With NLRP3
Authors: Kang-Zhen Zhang, Xi-Yu Shen, Man Wang, Li Wang, Hui-Xian Sun, Xiu-Zhen Li, Jing-Jing Huang, Xiao-Qing Li, Cheng Wu, Can Zhao, Jia-Li Liu, Xiang Lu, Wei Gao
Journal: J Am Heart Assoc
PubMed ID: 34726071
Doi: 10.1161/JAHA.121.022011
Products & Services: Recombinant Proteins   Protein Tools   
Management of COVID patients with convalescent plasma: Do we have the final word?
Authors: Francesco Menichetti, Marco Falcone, Giusy Tiseo
Journal: Eur J Intern Med
PubMed ID: 34895816
Doi: 10.1016/j.ejim.2021.10.029
Products & Services: Recombinant Proteins   
A study of cobalt (II) complexes involved in marine biogeochemical processes: Co(II)-1,10-Phenanthroline and Co(II)-1,10-Phenanthroline-L-α-Phosphatidylcholine
Authors: Anđela Bačinić, Sanja Frka, Marina Mlakar
Journal: Bioelectrochemistry
PubMed ID: 34902665
Doi: 10.1016/j.bioelechem.2021.108009
Products & Services: Peptide Synthesis   
Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies
Authors: Anilkumar Gopalakrishnapillai, Colin E Correnti, Kristina Pilat, Ida Lin, Man Kid Chan, Ashok D Bandaranayake, Christopher Mehlin, Anne Kisielewski, Darcy Hamill, Allison J Kaeding, Soheil Meshinchi, James M Olson, Edward Anders Kolb, Sonali P Barwe
Journal: Cancers (Basel)
PubMed ID: 34885074
Doi: 10.3390/cancers13235964
Products & Services: Gene Synthesis   
Overexpression of N-acetylglucosaminyltransferase V promotes human parotid gland acinar cell immortalization via the epidermal receptor activation
Authors: Ching-Chia Cheng, Chih-Feng Lin, Yong-Chong Lin, Tai-Horng Young, Pei-Jen Lou
Journal: J Cell Physiol
PubMed ID: 34806177
Doi: 10.1002/jcp.30641
Products & Services: Proteins, Expression, Isolation and Analysis   
Nucleic Acid Delivery from Granular Hydrogels
Authors: Evan Kurt, Tatiana Segura
Journal: Adv Healthc Mater
PubMed ID: 34742164
Doi: 10.1002/adhm.202101867
Products & Services: Proteins, Expression, Isolation and Analysis   
Assembly of pH-Responsive Antibody-Drug-Inspired Conjugates
Authors: Marco Raabe, Astrid Johanna Heck, Siska Führer, Dominik Schauenburg, Michaela Pieszka, Tao Wang, Maksymilian Marek Zegota, Lutz Nuhn, David Y W Ng, Seah Ling Kuan, Tanja Weil
Journal: Macromol Biosci
PubMed ID: 34791790
Doi: 10.1002/mabi.202100299
Products & Services: Proteins, Expression, Isolation and Analysis   
A single evolutionarily divergent mutation determines the different FAD-binding affinities of human and rat NQO1 due to site-specific phosphorylation
Authors: Juan Luis Pacheco-Garcia, Dmitry Loginov, Bruno Rizzuti, Pavla Vankova, Jose L Neira, Daniel Kavan, Noel Mesa-Torres, Rita Guzzi, Petr Man, Angel L Pey
Journal: FEBS Lett
PubMed ID: 34817874
Doi: 10.1002/1873-3468.14238
Products & Services: Gene Synthesis   
Genomic structure, expression, and functional characterization of the Fem-1 gene family in the redclaw crayfish, Cherax quadricarinatus
Authors: Jianbo Zheng, Leran Chen, Yongyi Jia, Meili Chi, Fei Li, Shun Cheng, Shili Liu, Yinuo Liu, Zhimin Gu
Journal: Gen Comp Endocrinol
PubMed ID: 34861280
Doi: 10.1016/j.ygcen.2021.113961
Products & Services: Gene Synthesis   
Commensal Strains Enhance the Efficacy of Neo-Epitope Based Cancer Vaccines
Authors: Michele Tomasi, Mattia Dalsass, Francesco Beghini, Ilaria Zanella, Elena Caproni, Laura Fantappiè, Assunta Gagliardi, Carmela Irene, Enrico König, Luca Frattini, Giulia Masetti, Samine Jessica Isaac, Federica Armanini, Fabio Cumbo, Aitor Blanco-Míguez, Alberto Grandi, Nicola Segata, Guido Grandi
Journal: Vaccines (Basel)
PubMed ID: 34835287
Doi: 10.3390/vaccines9111356
Products & Services: Peptide Synthesis   
Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease
Authors: Marcel V Alavi
Journal: Biochim Biophys Acta Mol Cell Res.
PubMed ID: 34400172
Doi: 10.1016/j.bbamcr.2021.119116
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Cyclic peptides with a distinct arginine-fork motif recognize the HIV trans-activation response RNA in vitro and in cells
Authors: Sai Shashank Chavali, Sachitanand M Mali, Rachel Bonn, Abhijith Saseendran Anitha, Ryan P Bennett, Harold C Smith, Rudi Fasan, Joseph E Wedekind
Journal: J Biol Chem.
PubMed ID: 34767799
Doi: 10.1016/j.jbc.2021.101390
Products & Services: Peptide Synthesis   
Quantifying charge state heterogeneity for proteins with multiple ionizable residues
Authors: Martin J Fossat, Ammon E Posey, Rohit V Pappu
Journal: Biophys J
PubMed ID: 34826385
Doi: 10.1016/j.bpj.2021.11.2886
Products & Services: Peptide Synthesis   
Silencing of SBF2-AS1 inhibits cell growth and invasion by sponging microRNA-338-3p in serous ovarian carcinoma
Authors: Ai-Ai Luan, Ling-Ling Hou, Fang-Yuan Zhang
Journal: Kaohsiung J Med Sci
PubMed ID: 34850542
Doi: 10.1002/kjm2.12479
Products & Services: Gene Synthesis   
Dl-3-N-Butylphthalide Attenuates Hypoxic Injury of Neural Stem Cells by Increasing Hypoxia-Inducible Factor-1alpha
Authors: Chaoqun Lin, Shiying Huang, Jianfeng Zhang, Huaitao Yuan, Tuchao Yao, Lukui Chen
Journal: J Stroke Cerebrovasc Dis
PubMed ID: 34837757
Doi: 10.1016/j.jstrokecerebrovasdis.2021.106221
Products & Services: Gene Synthesis   
The Hydrogen-Coupled Oligopeptide Membrane Cotransporter Pept2 is SUMOylated in Kidney Distal Convoluted Tubule Cells
Authors: Takwa S Aroankins, Sathish K Murali, Robert A Fenton, Qi Wu
Journal: Front Mol Biosci
PubMed ID: 34881291
Doi: 10.3389/fmolb.2021.790606
Products & Services: Gene Synthesis   
Characterization of the interaction domains between the phosphoprotein and the nucleoprotein of human Metapneumovirus
Authors: Hortense Decool, Benjamin Bardiaux, Luis Checa Ruano, Olivier Sperandio, Jenna Fix, Irina Gutsche, Charles-Adrien Richard, Monika Bajorek, Jean-François Eléouët, Marie Galloux
Journal: J Virol
PubMed ID: 34730389
Doi: 10.1128/JVI.00909-21
Products & Services: Gene Synthesis   
Neural-Cadherin Influences the Homing of Terminally Differentiated Memory CD8 T Cells to the Lymph Nodes and Bone Marrow
Authors: Kyong Hoon Kim, Aryeong Choi, Sang Hoon Kim, Heonju Song, Seohoon Jin, Kyungim Kim, Jaebong Jang, Hanbyeul Choi, Yong Woo Jung
Journal: Mol Cells
PubMed ID: 34819396
Doi: 10.14348/molcells.2021.0137
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Autophagy Regulates VDAC3 Ubiquitination by FBXW7 to Promote Erastin-Induced Ferroptosis in Acute Lymphoblastic Leukemia
Authors: Ting Zhu, Bo Liu, Di Wu, Gang Xu, Yang Fan
Journal: Front Cell Dev Biol
PubMed ID: 34869326
Doi: 10.3389/fcell.2021.740884
Products & Services: Custom DNA/RNA Oligos   
A poly(ethylene glycol) three-dimensional bone marrow hydrogel
Authors: Lauren E Jansen, Hyuna Kim, Christopher L Hall, Thomas P McCarthy, Michael J Lee, Shelly R Peyton
Journal: Biomaterials
PubMed ID: 34890973
Doi: 10.1016/j.biomaterials.2021.121270
Products & Services: Gene Synthesis   
Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs
Authors: Anjali Y Bhagirath, Vikram Bhatia, Manoj Reddy Medapati, Nisha Singh, Martha Hinton, Prashen Chelikani, Shyamala Dakshinamurti
Journal: FASEB Bioadv
PubMed ID: 35664968
Doi: 10.1096/fba.2021-00073
Products & Services: Mammalian Expression   
Vectored antibody gene delivery restores host B and T cell control of persistent viral infection
Authors: Yusuf I Ertuna, Benedict Fallet, Anna-Friederike Marx, Mirela Dimitrova, Anna Lena Kastner, Ingrid Wagner, Doron Merkler, Daniel D Pinschewer
Journal: Cell Rep
PubMed ID: 34852228
Doi: 10.1016/j.celrep.2021.110061
Products & Services: Mutagenesis Services   
Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro
Authors: Hsiang-Chi Huang, Yun-Ju Lai, Chun-Che Liao, Wang-Feng Yang, Ke-Bin Huang, I-Jung Lee, Wen-Cheng Chou, Shih-Han Wang, Ling-Hui Wang, Jung-Mao Hsu, Cheng-Pu Sun, Chun-Tse Kuo, Jyun Wang, Tzu-Chun Hsiao, Po-Jiun Yang, Te-An Lee, Wilson Huang, Fu-An Li, Chen-Yang Shen, Yi-Ling Lin, Mi-Hua Tao, Chia-Wei Li
Journal: EBioMedicine
PubMed ID: 34839261
Doi: 10.1016/j.ebiom.2021.103712
Products & Services: Proteins, Expression, Isolation and Analysis   
Rapid Response to SARS-CoV-2 in Aotearoa New Zealand: Implementation of a Diagnostic Test and Characterization of the First COVID-19 Cases in the South Island
Authors: Blair Lawley, Jenny Grant, Rhodri Harfoot, Jackson M Treece, Robert Day, Leonor C Hernández, Jo-Ann L Stanton, James E Ussher, Miguel E Quiñones-Mateu
Journal: Viruses
PubMed ID: 34835031
Doi: 10.3390/v13112222
Products & Services: Plasmid DNA Preparation   
MUC1 ectodomain is a flagellin-targeting decoy receptor and biomarker operative during Pseudomonas aeruginosa lung infection
Authors: Avelino C Verceles, Pavan Bhat, Zain Nagaria, Destiny Martin, Harsh Patel, Afua Ntem-Mensah, Sang W Hyun, Andrea Hahn, Jean Jeudy, Alan S Cross, Erik P Lillehoj, Simeon E Goldblum
Journal: Sci Rep
PubMed ID: 34811449
Doi: 10.1038/s41598-021-02242-x
Products & Services: Codon Optimization   
An ultra-low-cost electroporator with microneedle electrodes (ePatch) for SARS-CoV-2 vaccination
Authors: Dengning Xia, Rui Jin, Gaurav Byagathvalli, Huan Yu, Ling Ye, Chao-Yi Lu, M Saad Bhamla, Chinglai Yang, Mark R Prausnitz
Journal: Proc Natl Acad Sci U S A
PubMed ID: 34670842
Doi: 10.1073/pnas.2110817118
Products & Services: Plasmid DNA Preparation   
Development and Characterization of Magnetic SARS-CoV-2 Peptide-Imprinted Polymers
Authors: Beatriz Fresco-Cala, Soumya Rajpal, Tamara Rudolf, Benedikt Keitel, Rüdiger Groß, Jan Münch, Alex D Batista, Boris Mizaikoff
Journal: Nanomaterials (Basel)
PubMed ID: 34835749
Doi: 10.3390/nano11112985
Products & Services: Catalog Peptides   
Keratinocyte differentiation antigen-specific T cells in immune checkpoint inhibitor-treated NSCLC patients are associated with improved survival
Authors: Fiamma Berner, Rebekka Niederer, Jolien J Luimstra, Oltin Tiberiu Pop, Ann-Kristin Jochum, Mette-Triin Purde, Omar Hasan Ali, David Bomze, Jens Bauer, Lena Katharina Freudenmann, Ana Marcu, Eva-Maria Wolfschmitt, Sebastian Haen, Thorben Gross, Marissa Lisa Dubbelaar, Marie-Therese Abdou, Petra Baumgaertner, Christina Appenzeller, Caroline Cicin-Sain, Tobias Lenz, Daniel E Speiser, Burkhard Ludewig, Christoph Driessen, Markus Jörger, Martin Früh, Wolfram Jochum, Antonio Cozzio, Hans-Georg Rammensee, Juliane Walz, Jacques Neefjes, Lukas Flatz
Journal: Oncoimmunology
PubMed ID: 34858733
Doi: 10.1080/2162402X.2021.2006893
Products & Services: Peptide Synthesis   
Lipid-Binding Aegerolysin from Biocontrol Fungus
Authors: Nada Kraševec, Anastasija Panevska, Špela Lemež, Jaka Razinger, Kristina Sepčić, Gregor Anderluh, Marjetka Podobnik
Journal: Toxins (Basel)
PubMed ID: 34822604
Doi: 10.3390/toxins13110820
Products & Services: Bacterial Expression   
Structural evolution of a DNA repair self-resistance mechanism targeting genotoxic secondary metabolites
Authors: Elwood A Mullins, Jonathan Dorival, Gong-Li Tang, Dale L Boger, Brandt F Eichman
Journal: Nat Commun
PubMed ID: 34836957
Doi: 10.1038/s41467-021-27284-7
Products & Services: Custom Vector Construction   
VviPLATZ1 is a major factor that controls female flower morphology determination in grapevine
Authors: Pat Iocco-Corena, Jamila Chaïb, Laurent Torregrosa, Don Mackenzie, Mark R Thomas, Harley M Smith
Journal: Nat Commun
PubMed ID: 34848714
Doi: 10.1038/s41467-021-27259-8
The effect of Borago officinalis on the signaling pathway of the NLRP3 inflammasome complex, TLR4 and some inflammatory cytokines in type II diabetic patients with acute respiratory distress syndrome
Authors: Yanqiu Yue, Fengbin Jin, Xiaohui Yue
Journal: Cell Mol Biol (Noisy-le-grand)
PubMed ID: 34933712
Doi: 10.14715/cmb/2021.67.3.28
Products & Services: Custom DNA/RNA Oligos   
SNHG17, as an EMT-related lncRNA, promotes the expression of c-Myc by binding to c-Jun in esophageal squamous cell carcinoma
Authors: Supeng Shen, Jia Liang, Xiaoliang Liang, Gaoyan Wang, Bo Feng, Wei Guo, Yanli Guo, Zhiming Dong
Journal: Cancer Sci
PubMed ID: 34714590
Doi: 10.1111/cas.15184
Products & Services: Plasmid DNA Preparation   

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