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Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs
Authors: Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, David Groff, Wei Li, Moreno di Marco, Erin Runbeck, Hau Truong, Jugmohit S Toor, Sarvind Tripathi, Son Nguyen, Helena Shen, Tiffany Noel, Nicole L Church, Amber Weiner, Nathan Kendsersky, Dan Martinez, Rebecca Weisberg, Molly Christie, Laurence Eisenlohr, Kristopher R Bosse, Dimiter S Dimitrov, Stefan Stevanovic, Nikolaos G Sgourakis, Ben R Kiefel, John M Maris
Journal: Nature
PubMed ID: 34732890
Doi: 10.1038/s41586-021-04061-6
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Potentiality of Melittin-Loaded Niosomal Vesicles Against Vancomycin-Intermediate and Staphylococcal Skin Infection
Authors: Sirikwan Sangboonruang, Natthawat Semakul, Mohammad A Obeid, Marta Ruano, Kuntida Kitidee, Usanee Anukool, Kidsadagon Pringproa, Panuwan Chantawannakul, Valerie A Ferro, Yingmanee Tragoolpua, Khajornsak Tragoolpua
Journal: Int J Nanomedicine
PubMed ID: 34819727
Doi: 10.2147/IJN.S325901
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Multifunctional Dendronized Polypeptides for Controlled Adjuvanticity
Authors: Zhiyuan Fan, Sharon Jan, James C Hickey, D Huw Davies, Jiin Felgner, Philip L Felgner, Zhibin Guan
Journal: Biomacromolecules
PubMed ID: 34788023
Doi: 10.1021/acs.biomac.1c01052
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Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS
Authors: Hojae Lee, Jae Jin Lee, Na Young Park, Sandeep Kumar Dubey, Taeyong Kim, Kai Ruan, Su Bin Lim, Seong-Hyun Park, Shinwon Ha, Irina Kovlyagina, Kyung-Tai Kim, Seongjun Kim, Yohan Oh, Hyesoo Kim, Sung-Ung Kang, Mi-Ryoung Song, Thomas E Lloyd, Nicholas J Maragakis, Young Bin Hong, Hyungjin Eoh, Gabsang Lee
Journal: Nat Neurosci
PubMed ID: 34782793
Doi: 10.1038/s41593-021-00944-z
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SP-1154, a novel synthetic TGF-β inhibitor, alleviates obesity and hepatic steatosis in high-fat diet-induced mice
Authors: Kisoo Pahk, Sang Gil Lee, Chanmin Joung, Eun-Ok Kim, Hyun Woo Kwon, Dong Hwi Kim, Jong-Ik Hwang, Sungeun Kim, Won-Ki Kim
Journal: Biomed Pharmacother
PubMed ID: 34813997
Doi: 10.1016/j.biopha.2021.112441
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Insights into ROS-dependent signalling underlying transcriptomic plant responses to the herbicide 2,4-D
Authors: María C Romero-Puertas, M Ángeles Peláez-Vico, Diana M Pazmiño, María Rodríguez-Serrano, Laura Terrón-Camero, Rocío Bautista, Aurelio Gómez-Cadenas, M Gonzalo Claros, José León, Luisa M Sandalio
Journal: Plant Cell Environ
PubMed ID: 34800292
Doi: 10.1111/pce.14229
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The effects of Omarigliptin on promoting osteoblastic differentiation
Authors: Fake Liao, Xiunian Hu, Rijiang Chen
Journal: Bioengineered
PubMed ID: 34787070
Doi: 10.1080/21655979.2021.1999366
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An oral vaccine based on chitosan/aluminum adjuvant induces both local and systemic immune responses in turbot (Scophthalmus maximus)
Authors: Peng Jin, Fei Sun, Qin Liu, Qiyao Wang, Yuanxing Zhang, Xiaohong Liu
Journal: Vaccine
PubMed ID: 34844823
Doi: 10.1016/j.vaccine.2021.10.063
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Production, purification and characterization of a double-tagged TEV protease
Authors: Joaquín Dalla Rizza, Claudia Ortega, Federico Carrión, Martín Fló, Agustín Correa
Journal: Protein Expr Purif
PubMed ID: 34798273
Doi: 10.1016/j.pep.2021.106021
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Detection of Antibodies Against the SARS-CoV-2 Spike Protein and Analysis of the Peripheral Blood Mononuclear Cell Transcriptomic Profile, 15 Years After Recovery From SARS
Authors: Lili Zhao, Na Han, Yali Zheng, Huiying Rao, Jia Li, Yanwen Chen, Bing Yu, Yu Xu, Hongsong Chen, Zhancheng Gao, Baoguo Jiang
Journal: Front Cell Infect Microbiol
PubMed ID: 34869070
Doi: 10.3389/fcimb.2021.768993
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A binary effector module secreted by a type VI secretion system
Authors: Yasmin Dar, Biswanath Jana, Eran Bosis, Dor Salomon
Journal: EMBO Rep
PubMed ID: 34752000
Doi: 10.15252/embr.202153981
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High salt exacerbates acute kidney injury by disturbing the activation of CD5L/apoptosis inhibitor of macrophage (AIM) protein
Authors: Ching-Ting Wang, Tetsushi Tezuka, Naoki Takeda, Kimi Araki, Satoko Arai, Toru Miyazaki
Journal: PLoS ONE
PubMed ID: 34843572
Doi: 10.1371/journal.pone.0260449
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Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction
Authors: Christian Tüting, Fotis L Kyrilis, Johannes Müller, Marija Sorokina, Ioannis Skalidis, Farzad Hamdi, Yashar Sadian, Panagiotis L Kastritis
Journal: Nat Commun
PubMed ID: 34836937
Doi: 10.1038/s41467-021-27287-4
Products & Services: Proteins, Expression, Isolation and Analysis   
A Novel Serum tsRNA for Diagnosis and Prediction of Nephritis in SLE
Authors: Ping Yang, Xiaoshan Zhang, Shanshan Chen, Yue Tao, Mingzhe Ning, Yijia Zhu, Jun Liang, Wei Kong, Bo Shi, Zhiyang Li, Han Shen, Yanbo Wang
Journal: Front Immunol
PubMed ID: 34867955
Doi: 10.3389/fimmu.2021.735105
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A novel chimeric protein with enhanced cytotoxic effects on breast cancer in vitro and in vivo
Authors: Fereshte Hazrati, Massoud Saidijam, Yaghoub Ahmadyousefi, Fatemeh Nouri, Hamidreza Ghadimipour, Mohammadreza Moradi, Rasool Haddadi, Meysam Soleimani
Journal: Proteins
PubMed ID: 34812523
Doi: 10.1002/prot.26285
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Diagnostic Performance of Self-Collected Saliva Versus Nasopharyngeal Swab for the Molecular Detection of SARS-CoV-2 in the Clinical Setting
Authors: Mohammad Khaja Mafij Uddin, Tahmina Shirin, Mohammad Enayet Hossain, Ahmed Nawsher Alam, Jenifar Quaiyum Ami, Rashedul Hasan, Mojnu Miah, Nusrat Jahan Shaly, Shahriar Ahmed, S M Mazidur Rahman, Mustafizur Rahman, Sayera Banu
Journal: Microbiol Spectr
PubMed ID: 34730436
Doi: 10.1128/Spectrum.00468-21
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Identification and evolutionary analysis of the metal-tolerance protein family in eight Cucurbitaceae species
Authors: Xinchen Jiang, Junliang Yin, Lixin Wang, Keyong Xi, Xiongmeng Zhu, Gang Li, Yongxing Zhu, Yiqing Liu
Journal: Plant Genome
PubMed ID: 34741493
Doi: 10.1002/tpg2.20167
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Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis
Authors: Andrea Moreno, Victor Taleb, María Sebastián, Ernesto Anoz-Carbonell, Marta Martínez-Júlvez, Milagros Medina
Journal: IUBMB Life
PubMed ID: 34813144
Doi: 10.1002/iub.2576
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Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load
Authors: Akihiro Kaneshige, Takayuki Kaji, Lidan Zhang, Hayato Saito, Ayasa Nakamura, Tamaki Kurosawa, Madoka Ikemoto-Uezumi, Kazutake Tsujikawa, Shigeto Seno, Masatoshi Hori, Yasuyuki Saito, Takashi Matozaki, Kazumitsu Maehara, Yasuyuki Ohkawa, Michael Potente, Shuichi Watanabe, Thomas Braun, Akiyoshi Uezumi, So-Ichiro Fukada
Journal: Cell Stem Cell
PubMed ID: 34856120
Doi: 10.1016/j.stem.2021.11.003
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The circular RNA circSLC7A11 functions as a mir-330-3p sponge to accelerate hepatocellular carcinoma progression by regulating cyclin-dependent kinase 1 expression
Authors: Yu Huang, Wenhao Ge, Yuan Ding, Lufei Zhang, Jiarong Zhou, Yang Kong, Bijun Cui, Bingqiang Gao, Xiaohui Qian, Weilin Wang
Journal: Cancer Cell Int
PubMed ID: 34844614
Doi: 10.1186/s12935-021-02351-7
Products & Services: Proteins, Expression, Isolation and Analysis   
TAL effector-dependent Bax gene expression in transgenic rice confers disease resistance to Xanthomonas oryzae pv oryzae
Authors: Yuejing Gui, Dongsheng Tian, Kar Hui Ong, Joanne Chin Yi Teo, Zhongchao Yin
Journal: Transgenic Res
PubMed ID: 34748132
Doi: 10.1007/s11248-021-00290-7
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A super PPR cluster for restoring fertility revealed by genetic mapping, homocap-seq and de novo assembly in cotton
Authors: Bin Gao, Gaofeng Ren, Tianwang Wen, Haiping Li, Xianlong Zhang, Zhongxu Lin
Journal: Theor Appl Genet
PubMed ID: 34811574
Doi: 10.1007/s00122-021-03990-0
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An allergen-fused dendritic cell-binding peptide enhances in vitro proliferation of equine T-cells and cytokine production
Authors: Anja Ziegler, Judith Olzhausen, Eman Hamza, Ana Stojiljkovic, Michael H Stoffel, Mattia Garbani, Claudio Rhyner, Eliane Marti
Journal: Vet Immunol Immunopathol
PubMed ID: 34800874
Doi: 10.1016/j.vetimm.2021.110351
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Positively Regulates Pepper Immunity by Targeting against Inoculation through Modulating Defense-Related Genes
Authors: Ansar Hussain, Muhammad Ifnan Khan, Mohammed Albaqami, Shahzadi Mahpara, Ijaz Rasool Noorka, Mohamed A A Ahmed, Bandar S Aljuaid, Ahmed M El-Shehawi, Zhiqin Liu, Shahid Farooq, Ali Tan Kee Zuan
Journal: Int J Mol Sci
PubMed ID: 34769521
Doi: 10.3390/ijms222112091
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Mt10-CVB3 Vaccine Virus Protects against CVB4 Infection by Inducing Cross-Reactive, Antigen-Specific Immune Responses
Authors: Ninaad Lasrado, Rajkumar Arumugam, Mahima T Rasquinha, Meghna Sur, David Steffen, Jay Reddy
Journal: Microorganisms
PubMed ID: 34835449
Doi: 10.3390/microorganisms9112323
Products & Services: Proteins, Expression, Isolation and Analysis   
The pleiotropic functions of intracellular hydrophobins in aerial hyphae and fungal spores
Authors: Feng Cai, Zheng Zhao, Renwei Gao, Peijie Chen, Mingyue Ding, Siqi Jiang, Zhifei Fu, Pingyong Xu, Komal Chenthamara, Qirong Shen, Günseli Bayram Akcapinar, Irina S Druzhinina
Journal: PLoS Genet
PubMed ID: 34788288
Doi: 10.1371/journal.pgen.1009924
Products & Services: Proteins, Expression, Isolation and Analysis   
A conserved guided entry of tail-anchored pathway is involved in the trafficking of a subset of membrane proteins in Plasmodium falciparum
Authors: Tarkeshwar Kumar, Satarupa Maitra, Abdur Rahman, Souvik Bhattacharjee
Journal: PLoS Pathog
PubMed ID: 34780541
Doi: 10.1371/journal.ppat.1009595
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The synaptic scaffolding protein CNKSR2 interacts with CYTH2 to mediate hippocampal granule cell development
Authors: Hidenori Ito, Rika Morishita, Mariko Noda, Tomoki Ishiguro, Masashi Nishikawa, Koh-Ichi Nagata
Journal: J Biol Chem
PubMed ID: 34800437
Doi: 10.1016/j.jbc.2021.101427
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Microinjection of pruritogens in NGF-sensitized human skin
Authors: Hans Jürgen Solinski, Roman Rukwied, Martin Schmelz
Journal: Sci Rep
PubMed ID: 34728705
Doi: 10.1038/s41598-021-00935-x
Products & Services: Proteins, Expression, Isolation and Analysis   
A feminizing switch in a hemimetabolous insect
Authors: Ji-Chong Zhuo , Hou-Hong Zhang , Qing-Ling Hu , Jin-Li Zhang , Jia-Bao Lu , Han-Jing Li , Yu-Cheng Xie , Wei-Wei Wang , Yan Zhang , Hai-Qiang Wang , Hai-Jian Huang , Gang Lu , Jian-Ping Chen , Jun-Min Li , Zhi-Jian Tu , Chuan-Xi Zhang
Journal: Sci Adv
PubMed ID: 34826246
Doi: 10.1126/sciadv.abf9237
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A novel effector, CsSp1, from Bipolaris sorokiniana, is essential for colonization in wheat and is also involved in triggering host immunity
Authors: Wanying Zhang, Haiyang Li, Limin Wang, Shunpei Xie, Yuan Zhang, Ruijiao Kang, Mengjuan Zhang, Panpan Zhang, Yonghui Li, Yanfeng Hu, Min Wang, Linlin Chen, Hongxia Yuan, Shengli Ding, Honglian Li
Journal: Mol Plant Pathol
PubMed ID: 34741560
Doi: 10.1111/mpp.13155
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DNA Matrix Operation Based on the Mechanism of the DNAzyme Binding to Auxiliary Strands to Cleave the Substrate
Authors: Shaoxia Xu, Yuan Liu, Shihua Zhou, Qiang Zhang, Nikola K Kasabov
Journal: Biomolecules
PubMed ID: 34944442
Doi: 10.3390/biom11121797
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Lipopolysaccharide O-antigen molecular and supramolecular modifications of plant root microbiota are pivotal for host recognition
Authors: Adele Vanacore, Giuseppe Vitiello, Alan Wanke, Domenico Cavasso, Luke A Clifton, Lisa Mahdi, María Asunción Campanero-Rhodes, Dolores Solís, Manfred Wuhrer, Simone Nicolardi, Antonio Molinaro, Roberta Marchetti, Alga Zuccaro, Luigi Paduano, Alba Silipo
Journal: Carbohydr Polym
PubMed ID: 34893256
Doi: 10.1016/j.carbpol.2021.118839
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Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases
Authors: Zhirong Fu, Srinivas Akula, Anna-Karin Olsson, Jukka Kervinen, Lars Hellman
Journal: Int J Mol Sci
PubMed ID: 34884431
Doi: 10.3390/ijms222312627
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Patterns of Tetracapsuloides bryosalmonae infection of three salmonid species in large, deep Norwegian lakes
Authors: Tone Jøran Oredalen, Mona Saebø, Tor Atle Mo
Journal: J Fish Dis
PubMed ID: 34747501
Doi: 10.1111/jfd.13548
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Nanovesicles derived from bispecific CAR-T cells targeting the spike protein of SARS-CoV-2 for treating COVID-19
Authors: Tianchuan Zhu, Yuchen Xiao, Xiaojun Meng, Lantian Tang, Bin Li, Zhaoyan Zhao, Qingqin Tan, Hong Shan, Lei Liu, Xi Huang
Journal: J Nanobiotechnology
PubMed ID: 34823562
Doi: 10.1186/s12951-021-01148-0
Products & Services: Proteins, Expression, Isolation and Analysis   
The Excretory/Secretory and Surface Proteome Contains Putative Modulators of the Host Coagulation
Authors: Nina Gillis-Germitsch, Tobias Kockmann, Lars M Asmis, Lucienne Tritten, Manuela Schnyder
Journal: Front Cell Infect Microbiol
PubMed ID: 34796127
Doi: 10.3389/fcimb.2021.753320
Products & Services: Proteins, Expression, Isolation and Analysis   
Epitope-coated polymer particles elicit neutralising antibodies against Plasmodium falciparum sporozoites
Authors: Benjamin J Evert, Shuxiong Chen, Robyn McConville, Ryan W J Steel, Julie Healer, Justin A Boddey, Lucas Huntimer, Bernd H A Rehm
Journal: npj Vaccines
PubMed ID: 34845267
Doi: 10.1038/s41541-021-00408-2
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Proliferation of Tau 304-380 Fragment Aggregates through Autocatalytic Secondary Nucleation
Authors: Diana C Rodriguez Camargo, Eimantas Sileikis, Sean Chia, Emil Axell, Katja Bernfur, Rodrigo L Cataldi, Samuel I A Cohen, Georg Meisl, Johnny Habchi, Tuomas P J Knowles, Michele Vendruscolo, Sara Linse
Journal: ACS Chem Neurosci
PubMed ID: 34783519
Doi: 10.1021/acschemneuro.1c00454
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High-throughput and high-dimensional single-cell analysis of antigen-specific CD8 T cells
Authors: Ke-Yue Ma, Alexandra A Schonnesen, Chenfeng He, Amanda Y Xia, Eric Sun, Eunise Chen, Katherine R Sebastian, Yu-Wan Guo, Robert Balderas, Mrinalini Kulkarni-Date, Ning Jiang
Journal: Nat Immunol
PubMed ID: 34811538
Doi: 10.1038/s41590-021-01073-2
Products & Services: Proteins, Expression, Isolation and Analysis   
Assessment of an LSDV-Vectored Vaccine for Heterologous Prime-Boost Immunizations against HIV
Authors: Ros Chapman, Michiel van Diepen, Nicola Douglass, Shireen Galant, Mohamed Jaffer, Emmanuel Margolin, Phindile Ximba, Tandile Hermanus, Penny L Moore, Anna-Lise Williamson
Journal: Vaccines (Basel)
PubMed ID: 34835214
Doi: 10.3390/vaccines9111281
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Acute myeloid leukemia cell membrane-coated nanoparticles for cancer vaccination immunotherapy
Authors: Daniel T Johnson, Jiarong Zhou, Ashley V Kroll, Ronnie H Fang, Ming Yan, Crystal Xiao, Xiufen Chen, Justin Kline, Liangfang Zhang, Dong-Er Zhang
Journal: Leukemia
PubMed ID: 34845316
Doi: 10.1038/s41375-021-01432-w
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Scaling DNA data storage with nanoscale electrode wells
Authors: Bichlien H Nguyen, Christopher N Takahashi, Gagan Gupta, Jake A Smith, Richard Rouse, Paul Berndt, Sergey Yekhanin, David P Ward, Siena D Ang, Patrick Garvan, Hsing-Yeh Parker, Rob Carlson, Douglas Carmean, Luis Ceze, Karin Strauss
Journal: Sci Adv
PubMed ID: 34818035
Doi: 10.1126/sciadv.abi6714
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Construction of an enzyme-based all-fiber SPR biosensor for detection of enantiomers
Authors: Zhuoyue Zhou, Zhao Yang, Li Xia, Houjin Zhang
Journal: Biosens Bioelectron
PubMed ID: 34847363
Doi: 10.1016/j.bios.2021.113836
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Characterization of Anti-Ana o 3 Monoclonal Antibodies and Their Application in Comparing Brazilian Cashew Cultivars
Authors: Christopher P Mattison, Barry Vant-Hull, Ana Cecilia Ribeiro de Castro, Heidi J Chial, Yvette Bren-Mattison, Peter J Bechtel, Edy Sousa de Brito
Journal: Antibodies (Basel)
PubMed ID: 34939998
Doi: 10.3390/antib10040046
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Evaluation of the Immune Response of a Candidate Phage-Based Vaccine against (Cattle Tick)
Authors: Alejandro González-Mora, Kenny Misael Calvillo-Rodríguez, Jesús Hernández-Pérez, Marco Rito-Palomares, Ana Carolina Martínez-Torres, Jorge Benavides
Journal: Pharmaceutics
PubMed ID: 34959300
Doi: 10.3390/pharmaceutics13122018
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Performance Characteristics of High-Throughput Serologic Assays for Severe Acute Respiratory Syndrome Coronavirus 2 with Food and Drug Administration Emergency Use Authorization: A Review
Authors:
Journal: Clin Lab Med
PubMed ID: 35153046
Doi: 10.1016/j.cll.2021.10.006
Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release
Authors: Wanqiu Li, Linlin Wang, Bradley M. Wierbowski, Mo Lu, Feitong Dong, Wenchen Liu, Sisi Li, Peiyi Wang, Adrian Salic, Xin Gong
Journal: Nature Communications
Doi: doi.org/10.1038/s41467-021-27257-w
Products & Services: Proteins, Expression, Isolation and Analysis   
Conservation and Divergence of the Genes Related to Flowering and Circadian Rhythm in
Authors: Yuxi Chen, Rijin Zhou, Qiong Hu, Wenliang Wei, Jia Liu
Journal: Front Plant Sci
PubMed ID: 34880887
Doi: 10.3389/fpls.2021.760379
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Fecal microbiota changes in NZB/W F1 mice after induction of lupus disease
Authors: Yen-Fu Chen, Ao-Ho Hsieh, Lian-Chin Wang, Yun-Ju Huang, Wen-Yi Tseng, Yu-Lun Kuo, Shue-Fen Luo, Kuang-Hui Yu, Chang-Fu Kuo
Journal: Sci Rep
PubMed ID: 34824318
Doi: 10.1038/s41598-021-02422-9
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Interaction of Copper Trafficking Proteins with the Platinum Anticancer Drug Kiteplatin
Authors: Alessandra Barbanente, Angela Galliani, Rosa Maria Iacobazzi, Alessia Lasorsa, Maria Incoronata Nardella, Antonio Pennetta, Nicola Margiotta, Fabio Arnesano
Journal: ChemMedChem
PubMed ID: 34727402
Doi: 10.1002/cmdc.202100593
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Boosting BCG with recombinant influenza A virus tuberculosis vaccines increases pulmonary T cell responses but not protection against Mycobacterium tuberculosis infection
Authors: Heni Muflihah, Manuela Flórido, Leon C W Lin, Yingju Xia, James A Triccas, John Stambas, Warwick J Britton
Journal: PLoS ONE
PubMed ID: 34793507
Doi: 10.1371/journal.pone.0259829
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Improved Sensitivity of Allergen Detection by Immunoaffinity LC-MS/MS Using Ovalbumin as a Case Study
Authors: Martin Röder, Claudia Wiacek, Frauke Lankamp, Jonathan Kreyer, Wolfgang Weber, Elke Ueberham
Journal: Foods
PubMed ID: 34945483
Doi: 10.3390/foods10122932
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ILC3s control airway inflammation by limiting T cell responses to allergens and microbes
Authors: Fei Teng, Roser Tachó-Piñot, Biin Sung, Donna L Farber, Stefan Worgall, Hamida Hammad, Bart N Lambrecht, Matthew R Hepworth, Gregory F Sonnenberg
Journal: Cell Rep
PubMed ID: 34818549
Doi: 10.1016/j.celrep.2021.110051
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Unveiling mRNP composition by fluorescence correlation and cross-correlation spectroscopy using cell lysates
Authors: Àngels Mateu-Regué, Jan Christiansen, Frederik Otzen Bagger, Christian Hellriegel, Finn Cilius Nielsen
Journal: Nucleic Acids Res
PubMed ID: 34478550
Doi: 10.1093/nar/gkab751
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Nogo receptor impairs the clearance of fibril amyloid-β by microglia and accelerates Alzheimer's-like disease progression
Authors: Jianing Wang, Xiaoying Qin, Hao Sun, Meijun He, Qunyu Lv, Congcong Gao, Xinran He, Hong Liao
Journal: Aging Cell
PubMed ID: 34821024
Doi: 10.1111/acel.13515
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Spike residue 403 affects binding of coronavirus spikes to human ACE2
Authors: Fabian Zech, Daniel Schniertshauer, Christoph Jung, Alexandra Herrmann, Arne Cordsmeier, Qinya Xie, Rayhane Nchioua, Caterina Prelli Bozzo, Meta Volcic, Lennart Koepke, Janis A Müller, Jana Krüger, Sandra Heller, Steffen Stenger, Markus Hoffmann, Stefan Pöhlmann, Alexander Kleger, Timo Jacob, Karl-Klaus Conzelmann, Armin Ensser, Konstantin M J Sparrer, Frank Kirchhoff
Journal: Nat Commun
PubMed ID: 34824253
Doi: 10.1038/s41467-021-27180-0
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Immune reactivity and host modulatory roles of two novel Haemonchus contortus cathepsin B-like proteases
Authors: Mariam Bakshi, Wenbin Tuo, Raffi V Aroian, Dante Zarlenga
Journal: Parasit Vectors
PubMed ID: 34798906
Doi: 10.1186/s13071-021-05010-y
Products & Services: Proteins, Expression, Isolation and Analysis   
Piwi4 Structural Features Are Necessary for RNA Binding and Nuclear Localization
Authors: Adeline E Williams, Gaurav Shrivastava, Apostolos G Gittis, Sundar Ganesan, Ines Martin-Martin, Paola Carolina Valenzuela Leon, Ken E Olson, Eric Calvo
Journal: Int J Mol Sci
PubMed ID: 34884537
Doi: 10.3390/ijms222312733
Products & Services: Proteins, Expression, Isolation and Analysis   
Gain of Spontaneous Mutations Boosting Motility Adaption to Environments in
Authors: Bingyu Li, Chaofan Hou, Xian Ju, Yong Feng, Zhi-Qiang Ye, Yunzhu Xiao, Mingyao Gu, Chunxiang Fu, Chaoliang Wei, Conghui You
Journal: Front Bioeng Biotechnol
PubMed ID: 34900963
Doi: 10.3389/fbioe.2021.772397
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G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators
Authors: Malarvizhi Gurusamy, Denise Tischner, Jingchen Shao, Stephan Klatt, Sven Zukunft, Remy Bonnavion, Stefan Günther, Kai Siebenbrodt, Roxane-Isabelle Kestner, Tanja Kuhlmann, Ingrid Fleming, Stefan Offermanns, Nina Wettschureck
Journal: Nat Commun
PubMed ID: 34815397
Doi: 10.1038/s41467-021-26882-9
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TIFAB accelerates MLL-AF9-Induced acute myeloid leukemia through upregulation of HOXA9
Authors: Jinming Zhao, Yan Xiu, Lin Fu, Qianze Dong, Nicholas Borcherding, Yang Wang, Qingchang Li, Nilushi S De Silva, Ulf Klein, Brendan F Boyce, Chen Zhao
Journal: iScience
PubMed ID: 34877491
Doi: 10.1016/j.isci.2021.103425
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Curcumol inhibits malignant biological behaviors and TMZ-resistance in glioma cells by inhibiting long noncoding RNA FOXD2-As1-promoted EZH2 activation
Authors: Xuyang Lv, Jiangchuan Sun, Linfeng Hu, Ying Qian, Chunlei Fan, Nan Tian
Journal: Aging (Albany NY)
PubMed ID: 34739394
Doi: 10.18632/aging.203662
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Plant LHC-like proteins show robust folding and static non-photochemical quenching
Authors: Petra Skotnicová, Hristina Staleva-Musto, Valentyna Kuznetsova, David Bína, Minna M Konert, Shan Lu, Tomáš Polívka, Roman Sobotka
Journal: Nat Commun
PubMed ID: 34824207
Doi: 10.1038/s41467-021-27155-1
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A nanocompartment system contributes to defense against oxidative stress in
Authors: Katie A Lien, Kayla Dinshaw, Robert J Nichols, Caleb Cassidy-Amstutz, Matthew Knight, Rahul Singh, Lindsay D Eltis, David F Savage, Sarah A Stanley
Journal: Elife
PubMed ID: 34751132
Doi: 10.7554/eLife.74358
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Limited Impact of Delta Variant's Mutations on the Effectiveness of Neutralization Conferred by Natural Infection or COVID-19 Vaccines in a Latino Population
Authors: Carlos A Sariol, Crisanta Serrano-Collazo, Edwin J Ortiz, Petraleigh Pantoja, Lorna Cruz, Teresa Arana, Dianne Atehortua, Christina Pabon-Carrero, Ana M Espino
Journal: Viruses
PubMed ID: 34960674
Doi: 10.3390/v13122405
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Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages
Authors: Christian Kretzer, Paul M Jordan, Katharina P L Meyer, Daniel Hoff, Markus Werner, Robert Klaus Hofstetter, Andreas Koeberle, Antonio Cala Peralta, Guillaume Viault, Denis Seraphin, Pascal Richomme, Jean-Jacques Helesbeux, Hermann Stuppner, Veronika Temml, Daniela Schuster, Oliver Werz
Journal: Biochem Pharmacol
PubMed ID: 34762841
Doi: 10.1016/j.bcp.2021.114825
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Translational activators and mitoribosomal isoforms cooperate to mediate mRNA-specific translation in Schizosaccharomyces pombe mitochondria
Authors: Christopher J Herbert, Sylvie Labarre-Mariotte, David Cornu, Cyrielle Sophie, Cristina Panozzo, Thomas Michel, Geneviève Dujardin, Nathalie Bonnefoy
Journal: Nucleic Acids Res
PubMed ID: 34634819
Doi: 10.1093/nar/gkab789
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An acetylation-enhanced interaction between transcription factor Sox2 and the steroid receptor coactivators facilitates Sox2 transcriptional activity and function
Authors: Yuanyong Huang, Xiaoya Duan, Zhen Wang, Yimei Sun, Qingqing Guan, Li Kang, Qiao Zhang, Lan Fang, Jiwen Li, Jiemin Wong
Journal: J Biol Chem
PubMed ID: 34762910
Doi: 10.1016/j.jbc.2021.101389
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His domain protein tyrosine phosphatase and Rabaptin-5 couple endo-lysosomal sorting of EGFR with endosomal maturation
Authors: Gabrielle Parkinson, Peristera Roboti, Ling Zhang, Sandra Taylor, Philip Woodman
Journal: J Cell Sci
PubMed ID: 34657963
Doi: 10.1242/jcs.259192
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Comprehensive Comparative Analysis of the GATA Transcription Factors in Four Rosaceae Species and Phytohormonal Response in Chinese Pear () Fruit
Authors: Muhammad Aamir Manzoor, Irfan Ali Sabir, Iftikhar Hussain Shah, Han Wang, Zhao Yu, Faiz Rasool, Muhammad Zaid Mazhar, Shoaib Younas, Muhammad Abdullah, Yongping Cai
Journal: Int J Mol Sci
PubMed ID: 34830372
Doi: 10.3390/ijms222212492
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Novel immortalization approach defers senescence of cultured canine adipose-derived mesenchymal stromal cells
Authors: Ana Stojiljković, Véronique Gaschen, Franck Forterre, Ulrich Rytz, Michael H Stoffel, Jasmin Bluteau
Journal: Geroscience
PubMed ID: 34806133
Doi: 10.1007/s11357-021-00488-x
Products & Services: ORF cDNA Clones/MolecularCloud   
Hsa_circRNA_103124 Upregulation in Crohn's Disease Promotes Cell Proliferation and Inhibits Autophagy by Regulating the Hsa-miR-650/AKT2 Signaling Pathway
Authors: Juan Yin, Fuyi Tong, Yulan Ye, Tong Hu, Lijuan Xu, Liping Zhang, Jianyun Zhu, Zhi Pang
Journal: Front Genet
PubMed ID: 34804121
Doi: 10.3389/fgene.2021.753161
Products & Services: Gene Synthesis   
Insulin-like growth factor 2 mRNA binding protein 2 regulates proliferation, migration and angiogenesis of keratinocytes by modulating heparanase stability
Authors: Shaomin Zhi, Jun Li, Xiao Kong, Xuemei Xie, Qiangli Zhang, Guoxiang Fang
Journal: Bioengineered
PubMed ID: 34753397
Doi: 10.1080/21655979.2021.2002495
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Reconstitution and use of highly active human CDK1:Cyclin-B:CKS1 complexes
Authors: Pim J Huis In 't Veld, Sabine Wohlgemuth, Carolin Koerner, Franziska Müller, Petra Janning, Andrea Musacchio
Journal: Protein Sci
PubMed ID: 34791727
Doi: 10.1002/pro.4233
Products & Services: Proteins, Expression, Isolation and Analysis   
SARS-CoV-2 nucleocapsid protein interacts with immunoregulators and stress granules and phase separates to form liquid droplets
Authors: Syam Prakash Somasekharan, Martin Gleave
Journal: FEBS Lett
PubMed ID: 34780058
Doi: 10.1002/1873-3468.14229
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Serine palmitoyltransferase assembles at ER-mitochondria contact sites
Authors: Mari J Aaltonen, Irina Alecu, Tim König, Steffany Al Bennett, Eric A Shoubridge
Journal: Life Sci Alliance
PubMed ID: 34785538
Doi: 10.26508/lsa.202101278
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SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II
Authors: Richard King, Zesen Lin, Ginette Balbin-Cuesta, Gregg Myers, Ann Friedman, Guojing Zhu, Beth McGee, Thomas L Saunders, Ryo Kurita, Yukio Nakamura, James Douglas Engel, Pavan Reddy, Rami Khoriaty
Journal: Sci Adv
PubMed ID: 34818036
Doi: 10.1126/sciadv.abj5293
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MLL1 is regulated by KSHV LANA and is important for virus latency
Authors: Min Tan, Shijun Li, Franceline Juillard, Rute Chitas, Tânia F Custódio, Han Xue, Agnieszka Szymula, Qiming Sun, Bing Liu, Ángel L Álvarez, She Chen, Jing Huang, J Pedro Simas, Colin E McVey, Kenneth M Kaye
Journal: Nucleic Acids Res
PubMed ID: 34850113
Doi: 10.1093/nar/gkab1094
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A cell-based multiplex immunoassay platform using fluorescent protein-barcoded reporter cell lines
Authors: Shengli Song, Miriam Manook, Jean Kwun, Annette M Jackson, Stuart J Knechtle, Garnett Kelsoe
Journal: Commun Biol
PubMed ID: 34824350
Doi: 10.1038/s42003-021-02881-w
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Protoplast isolation and transcriptome analysis of developing xylem in Pinus massoniana (Pinaceae)
Authors: Tengfei Shen, Mengxuan Xu, Haoran Qi, Yuanheng Feng, Zhangqi Yang, Meng Xu
Journal: Mol Biol Rep
PubMed ID: 34826048
Doi: 10.1007/s11033-021-06995-6
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Association between angiotensinogen (AGT), angiotensin-converting enzyme (ACE) and angiotensin-II receptor 1 (AGTR1) polymorphisms and COVID-19 infection in the southeast of Iran: a preliminary case-control study
Authors: Hamid Reza Kouhpayeh, Farhad Tabasi, Mohammad Dehvari, Mohammad Naderi, Gholamreza Bahari, Tahereh Khalili, Courtney Clark, Saeid Ghavami, Mohsen Taheri
Journal: Transl Med Commun
PubMed ID: 34805533
Doi: 10.1186/s41231-021-00106-0
Products & Services: Gene Synthesis   
Prevalence of SARS-CoV-2 Antibody in 2,935 Healthcare Workers at 6 Major Hospitals, Daegu, Korea
Authors: Yu Kyung Kim, Dohsik Minn, Do Young Song, Chae Hoon Lee, Nam Hee Ryoo, Chang-Ho Jeon, Kyung Eun Song, Jang Soo Suh, Soon Hee Chang
Journal: J Korean Med Sci
PubMed ID: 34751011
Doi: 10.3346/jkms.2021.36.e294
AZD3759 enhances radiation effects in non-small-cell lung cancer by a synergistic blockade of epidermal growth factor receptor and Janus kinase-1
Authors: Ruing Zhao, Wei Yin, Qingqing Yu, Yanjiao Mao, Qinghua Deng, Ke Zhang, Shenglin Ma
Journal: Bioengineered
PubMed ID: 34738874
Doi: 10.1080/21655979.2021.2001238
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Development of surface engineered antigenic exosomes as vaccines for respiratory syncytial virus
Authors: Suyeon Hong, Shaobo Ruan, Zachary Greenberg, Mei He, Jodi L McGill
Journal: Sci Rep
PubMed ID: 34725399
Doi: 10.1038/s41598-021-00765-x
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CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation
Authors: Lorna M Stewart, Lisa Gerner, Mandy Rettel, Frank Stein, James F Burrows, Ian G Mills, Emma Evergren
Journal: Cell Death Dis
PubMed ID: 34725334
Doi: 10.1038/s41419-021-04335-x
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Breadth of CD8 T-cell mediated inhibition of replication of diverse HIV-1 transmitted-founder isolates correlates with the breadth of recognition within a comprehensive HIV-1 Gag, Nef, Env and Pol potential T-cell epitope (PTE) peptide set
Authors: Peter Hayes, Natalia Fernandez, Christina Ochsenbauer, Jama Dalel, Jonathan Hare, Deborah King, Lucas Black, Claire Streatfield, Vanaja Kakarla, Gladys Macharia, Julia Makinde, Matt Price, Eric Hunter, Jill Gilmour
Journal: PLoS ONE
PubMed ID: 34788349
Doi: 10.1371/journal.pone.0260118
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Antiseptic 9-Meric Peptide with Potency against Carbapenem-Resistant Infection
Authors: Manigandan Krishnan, Joonhyeok Choi, Ahjin Jang, Young Kyung Yoon, Yangmee Kim
Journal: Int J Mol Sci
PubMed ID: 34830401
Doi: 10.3390/ijms222212520
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Long noncoding RNA SNHG25 promotes the malignancy of endometrial cancer by sponging microRNA-497-5p and increasing FASN expression
Authors: Yuhua He, Shuifang Xu, Yi Qi, Jinfang Tian, Fengying Xu
Journal: J Ovarian Res
PubMed ID: 34789312
Doi: 10.1186/s13048-021-00906-w
Products & Services: Plasmid DNA Preparation   
Comparison of Antibody Response Elicited by ChAdOx1 and BNT162b2 COVID-19 Vaccine
Authors: Yu Min Kang, Dohsik Minn, Jaegyun Lim, Ki-Deok Lee, Dong Ho Jo, Kang-Won Choe, Moon Jung Kim, Jong Min Kim, Kwang Nam Kim
Journal: J Korean Med Sci
PubMed ID: 34845875
Doi: 10.3346/jkms.2021.36.e311
PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates
Authors: Nobuyuki Shimizu, Tomoko Asatsuma-Okumura, Junichi Yamamoto, Yuki Yamaguchi, Hiroshi Handa, Takumi Ito
Journal: Commun Biol
PubMed ID: 34764413
Doi: 10.1038/s42003-021-02801-y
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PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ
Authors: Fengxiang Wang, Emily T Graham, Nathchar Naowarojna, Zhennan Shi, Yuqi Wang, Guanglei Xie, Lili Zhou, Wendy Salmon, Jie-Min Jia, Xi Wang, Yuwei Huang, Stuart L Schreiber, Yilong Zou
Journal: Cell Chem Biol
PubMed ID: 34813762
Doi: 10.1016/j.chembiol.2021.11.001
Products & Services: Proteins, Expression, Isolation and Analysis   
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats
Authors: Xuankang Wang, Xin Li, Xiaoshuang Zuo, Zhuowen Liang, Tan Ding, Kun Li, Yangguang Ma, Penghui Li, Zhijie Zhu, Cheng Ju, Zhihao Zhang, Zhiwen Song, Huilin Quan, Jiawei Zhang, Xueyu Hu, Zhe Wang
Journal: J Neuroinflammation
PubMed ID: 34740378
Doi: 10.1186/s12974-021-02312-x
Products & Services: Proteins, Expression, Isolation and Analysis   
3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels
Authors: Niraimathi Govindasamy, Hongyan Long, Hyun-Woo Jeong, Ratish Raman, Burak Özcifci, Simone Probst, Sebastian J Arnold, Kristina Riehemann, Adrian Ranga, Ralf H Adams, Britta Trappmann, Ivan Bedzhov
Journal: Dev Cell
PubMed ID: 34741805
Doi: 10.1016/j.devcel.2021.10.014
Products & Services: Proteins, Expression, Isolation and Analysis   
Capillary electrophoresis-based functional genomics screening to discover novel archaeal DNA modifying enzymes
Authors: Kelly M Zatopek, Samantha L Fossa, Katharina Bilotti, Paul J Caffrey, Léa Chuzel, Alexandra M Gehring, Gregory J S Lohman, Christopher H Taron, Andrew F Gardner
Journal: Appl Environ Microbiol
PubMed ID: 34788065
Doi: 10.1128/AEM.02137-21
Products & Services: Plasmid DNA Preparation   
New highly antigenic linear B cell epitope peptides from PvAMA-1 as potential vaccine candidates
Authors: Raianna F Fantin, Vanessa G Fraga, Camila A Lopes, Isabella C de Azevedo, João L Reis-Cunha, Dhelio B Pereira, Francisco P Lobo, Marcela M de Oliveira, Anderson C Dos Santos, Daniela C Bartholomeu, Ricardo T Fujiwara, Lilian L Bueno
Journal: PLoS ONE
PubMed ID: 34727117
Doi: 10.1371/journal.pone.0258637
Products & Services: Plasmid DNA Preparation   
The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1
Authors: Beatriz Sanchez-Solana, Dunrui Wang, Xiaolan Qian, Parthibane Velayoudame, Dhirendra K Simanshu, Jairaj K Acharya, Douglas R Lowy
Journal: Mol Cancer
PubMed ID: 34727930
Doi: 10.1186/s12943-021-01439-y
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The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses
Authors: David M Picton, Yvette A Luyten, Richard D Morgan, Andrew Nelson, Darren L Smith, David T F Dryden, Jay C D Hinton, Tim R Blower
Journal: Nucleic Acids Res
PubMed ID: 34657954
Doi: 10.1093/nar/gkab906
Products & Services: Mutant Libraries   
Effector-mediated membrane disruption controls cell death in CBASS antiphage defense
Authors: Brianna Duncan-Lowey, Nora K McNamara-Bordewick, Nitzan Tal, Rotem Sorek, Philip J Kranzusch
Journal: Mol Cell
PubMed ID: 34784509
Doi: 10.1016/j.molcel.2021.10.020
Products & Services: Mutant Libraries   
Stress Induced Transcription Factors Transactivate the Herpes Simplex Virus 1 Infected Cell Protein 27 (ICP27) Transcriptional Enhancer
Authors: Jeffery B Ostler, Clinton Jones
Journal: Viruses
PubMed ID: 34835102
Doi: 10.3390/v13112296
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