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Transcription factor specificity protein 1-mediated Serine/threonine kinase 39 upregulation promotes the proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells by activating the transforming growth factor-β1 /Smad2/3 pathway

Authors: Jing Wang, Zhenyu Fan, Jia Li, Jingmao Yang, Xiaofei Liu, Jilin Cheng

Journal: Bioengineered

PubMed ID: 34281492

Doi: 10.1080/21655979.2021.1947939

Products & Services: Proteins, Expression, Isolation and Analysis

Correction to: Expanding the Genetic and Phenotypic Spectrum of Female Infertility Caused by TUBB8 Mutations

Authors: Qianneng Lu, Xiaolan Zhang, Qiqi Cao, Congjing Wang, Jie Ding, Chun Zhao, Junqiang Zhang, Xiufeng Ling, Qingxia Meng, Ran Huo, Hong Li

Journal: Reprod Sci

PubMed ID: 34542892

Doi: 10.1007/s43032-021-00742-9

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Melatonin protects H9c2 cardiomyoblasts from oxygen glucose deprivation and reperfusion-induced injury by inhibiting Rac1/JNK/Foxo3a/Bim signaling pathway

Authors: Yulin Wang, Ying Jian, Xiaofu Zhang, Bin Ni, Mingwei Wang, Chunqi Pan

Journal: Cell Biol Int

PubMed ID: 34882903

Doi: 10.1002/cbin.11739

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Enhancing the detection sensitivity of nanobody against aflatoxin B through structure-guided modification

Authors: Ting He, Yao Nie, Tingting Yan, Jiang Zhu, Xiaoling He, Ying Li, Qi Zhang, Xiaoqian Tang, Rui Hu, Yunhuang Yang, Maili Liu

Journal: Int J Biol Macromol

PubMed ID: 34863829

Doi: 10.1016/j.ijbiomac.2021.11.182

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Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials

Authors: Gang Zeng, Qianhui Wu, Hongxing Pan, Minjie Li, Juan Yang, Lin Wang, Zhiwei Wu, Deyu Jiang, Xiaowei Deng, Kai Chu, Wen Zheng, Lei Wang, Wanying Lu, Bihua Han, Yuliang Zhao, Fengcai Zhu, Hongjie Yu, Weidong Yin

Journal: Lancet Infect Dis

PubMed ID: 34890537

Doi: 10.1016/S1473-3099(21)00681-2

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A new self-attenuated therapeutic influenza vaccine that uses host cell-restricted attenuation by artificial microRNAs

Authors: Ke Wen, Haiyan Wang, Yanping Chen, Huixiao Yang, Zhichao Zheng, Yongyong Yan, Realivazquez Adilene, Mingtao Zeng

Journal: Int J Pharm

PubMed ID: 34883209

Doi: 10.1016/j.ijpharm.2021.121325

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Low-dose cyclooxygenase-2 (COX-2) inhibitor celecoxib plays a protective role in the rat model of neonatal necrotizing enterocolitis

Authors:

Journal: Bioengineered

PubMed ID: 34546832

Doi: 10.1080/21655979.2021.1980646

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4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase

Authors: Emma G Jackson, Giuliano Cutolo, Bo Yang, Nageswari Yarravarapu, Mary W N Burns, Ganka Bineva-Todd, Chloë Roustan, James B Thoden, Halley M Lin-Jones, Toin H van Kuppevelt, Hazel M Holden, Benjamin Schumann, Jennifer J Kohler, Christina M Woo, Matthew R Pratt

Journal: ACS Chem Biol

PubMed ID: 34931806

Doi: 10.1021/acschembio.1c00818

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Ultrasound treatment can increase digestibility of myofibrillar protein of pork with modified atmosphere packaging

Authors: Shuai Jiang, Miao Zhang, Hui Liu, Qian Li, Dejiang Xue, Yingqun Nian, Di Zhao, Kai Shan, Chen Dai, Chunbao Li

Journal: Food Chem

PubMed ID: 35030336

Doi: 10.1016/j.foodchem.2021.131811

Products & Services: Proteins, Expression, Isolation and Analysis

Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors

Authors: Tamara Muliaditan, Leena Halim, Lynsey M Whilding, Benjamin Draper, Daniela Y Achkova, Fahima Kausar, Maya Glover, Natasha Bechman, Appitha Arulappu, Jenifer Sanchez, Katie R Flaherty, Jana Obajdin, Kristiana Grigoriadis, Pierre Antoine, Daniel Larcombe-Young, Caroline M Hull, Richard Buus, Peter Gordon, Anita Grigoriadis, David M Davies, Anna Schurich, John Maher

Journal: Cell Rep Med

PubMed ID: 35028604

Doi: 10.1016/j.xcrm.2021.100457

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Novel pentose-regulated promoter of with application in controlling heterologous gene expression

Authors: Sukanya Jeennor, Jutamas Anantayanon, Chanikul Chutrakul, Sarocha Panchanawaporn, Kobkul Laoteng

Journal: Biotechnol Rep (Amst)

PubMed ID: 35004236

Doi: 10.1016/j.btre.2021.e00695

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Soybean miR159 Regulatory Network Involved in Gibberellin-Modulated Resistance to

Authors: Piao Lei, Nawei Qi, Yuan Zhou, Yuanyuan Wang, Xiaofeng Zhu, Yuanhu Xuan, Xiaoyu Liu, Haiyan Fan, Lijie Chen, Yuxi Duan

Journal: Int J Mol Sci

PubMed ID: 34884977

Doi: 10.3390/ijms222313172

Products & Services: Proteins, Expression, Isolation and Analysis

Expression profile of RNA binding protein in cervical cancer using bioinformatics approach

Authors: Zhiyuan Huang, Fang Li, Qinchuan Li

Journal: Cancer Cell Int

PubMed ID: 34863153

Doi: 10.1186/s12935-021-02319-7

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Non-β-blocker enantiomers of propranolol and atenolol inhibit vasculogenesis in infantile hemangioma

Authors: Caroline T Seebauer, Matthew S Graus, Lan Huang, Alex J McCann, Jill Wylie-Sears, Frank R Fontaine, Tara Karnezis, David Zurakowski, Steven J Staffa, Frédéric A Meunier, John B Mulliken, Joyce Bischoff, Mathias Francois

Journal: J Clin Invest

PubMed ID: 34874911

Doi: 10.1172/JCI151109

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RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation

Authors: Fabian Poetz, Joshua Corbo, Yevgen Levdansky, Alexander Spiegelhalter, Doris Lindner, Vera Magg, Svetlana Lebedeva, Jörg Schweiggert, Johanna Schott, Eugene Valkov, Georg Stoecklin

Journal: Nat Commun

PubMed ID: 34887419

Doi: 10.1038/s41467-021-27471-6

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HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma

Authors: Benjy Jy Tan, Kenji Sugata, Omnia Reda, Misaki Matsuo, Kyosuke Uchiyama, Paola Miyazato, Vincent Hahaut, Makoto Yamagishi, Kaoru Uchimaru, Yutaka Suzuki, Takamasa Ueno, Hitoshi Suzushima, Hiroo Katsuya, Masahito Tokunaga, Yoshikazu Uchiyama, Hideaki Nakamura, Eisaburo Sueoka, Atae Utsunomiya, Masahiro Ono, Yorifumi Satou

Journal: J Clin Invest

PubMed ID: 34907908

Doi: 10.1172/JCI150472

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Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

Authors: Yukiko Sato, Kamila R Mustafina, Yishan Luo, Carolina Martini, David Y Thomas, Paul W Wiseman, John W Hanrahan

Journal: Sci Rep

PubMed ID: 34853321

Doi: 10.1038/s41598-021-02420-x

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GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1

Authors: Lucia Balazova, Miroslav Balaz, Carla Horvath, Áron Horváth, Caroline Moser, Zuzana Kovanicova, Adhideb Ghosh, Umesh Ghoshdastider, Vissarion Efthymiou, Elke Kiehlmann, Wenfei Sun, Hua Dong, Lianggong Ding, Ez-Zoubir Amri, Pirjo Nuutila, Kirsi A Virtanen, Tarja Niemi, Barbara Ukropcova, Jozef Ukropec, Pawel Pelczar, Thorsten Lamla, Bradford Hamilton, Heike Neubauer, Christian Wolfrum

Journal: Nat Commun

PubMed ID: 34880217

Doi: 10.1038/s41467-021-27442-x

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Rice stripe virus activates the bZIP17/28 branch of the unfolded protein response signalling pathway to promote viral infection

Authors: Chenyang Li, Tianze Zhang, Yu Liu, Zongdi Li, Yaqin Wang, Shuai Fu, Yi Xu, Tong Zhou, Jianxiang Wu, Xueping Zhou

Journal: Mol Plant Pathol

PubMed ID: 34897936

Doi: 10.1111/mpp.13171

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Seven-Month Analysis of Five SARS-CoV-2 Antibody Assay Results after ChAdOx1 nCoV-19 Vaccination: Significant Decrease in SARS-CoV-2 Antibody Titer

Authors: Seri Jeong, Nuri Lee, Su-Kyung Lee, Eun-Jung Cho, Jungwon Hyun, Min-Jeong Park, Wonkeun Song, Eun-Ju Jung, Heungjeong Woo, Yu-Bin Seo, Jin-Ju Park, Hyun-Soo Kim

Journal: Diagnostics (Basel)

PubMed ID: 35054251

Doi: 10.3390/diagnostics12010085

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Deferasirox combination with eltrombopag shows anti-myelodysplastic syndrome effects by enhancing iron deprivation-related apoptosis

Authors: Lei Huang, Mengyue Tian, Zhaoyun Liu, Chunyan Liu, Rong Fu

Journal: J Investig Med

PubMed ID: 34921125

Doi: 10.1136/jim-2021-002147

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Seven-Month Analysis of Five SARS-CoV-2 Antibody Assay Results after ChAdOx1 nCoV-19 Vaccination: Significant Decrease in SARS-CoV-2 Antibody Titer

Authors: Seri Jeong, Nuri Lee, Su-Kyung Lee, Eun-Jung Cho, Jungwon Hyun, Min-Jeong Park, Wonkeun Song, Eun-Ju Jung, Heungjeong Woo, Yu-Bin Seo, Jin-Ju Park, Hyun-Soo Kim

Journal: Diagnostics (Basel)

PubMed ID: 35054251

Doi: 10.3390/diagnostics12010085

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Adenovirus-mediated RNA interference against herpes simplex virus infection in vitro

Authors: Lin Chen, Zhi-Qiang Pan, Chang-Bin Zhai

Journal: Folia Histochem Cytobiol

PubMed ID: 34905214

Doi: 10.5603/FHC.a2021.0031

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Key factors determining competitions between double-stranded RNAs in Tribolium castaneum

Authors: Xu Shen, Yingchuan Peng, Huifang Song, Jinda Wang, Jun Zhao, Peian Tang, Zhaojun Han, Kangxu Wang

Journal: Pestic Biochem Physiol

PubMed ID: 35082032

Doi: 10.1016/j.pestbp.2021.105009

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Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis

Authors: Yi-Ping Liu, Zhong-Zhi Qiu, Xu-Hui Li, En-You Li

Journal: World J Gastrointest Oncol

PubMed ID: 35070046

Doi: 10.4251/wjgo.v13.i12.2114

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KIAA1217 Promotes Epithelial-Mesenchymal Transition and Hepatocellular Carcinoma Metastasis by Interacting with and Activating STAT3

Authors: Yanhong Wang, Na Li, Yanping Zheng, Anqing Wang, Chunlei Yu, Zhenbo Song, Shuyue Wang, Ying Sun, Lihua Zheng, Guannan Wang, Lei Liu, Jingwen Yi, Yanxin Huang, Muqing Zhang, Yongli Bao, Luguo Sun

Journal: Int J Mol Sci

PubMed ID: 35008530

Doi: 10.3390/ijms23010104

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Exposure to in Asian Elephants () in Thailand

Authors: Ruenruetai Udonsom, Yoshifumi Nishikawa, Ragab M Fereig, Thitirat Topisit, Natchakorn Kulkaweewut, Supitcha Chanamrung, Charoonluk Jirapattharasate

Journal: Pathogens

PubMed ID: 35055950

Doi: 10.3390/pathogens11010002

Products & Services: Proteins, Expression, Isolation and Analysis

Widely heterogeneous humoral and cellular immunity after mild SARS-CoV-2 infection in a homogeneous population of healthy young men

Authors: Nina Le Bert, Wan Ni Chia, Wei Yee Wan, Alvin Kuo Jing Teo, Samuel Zeng-Rong Chong, Nicole Tan, Doreen Soek Chin Tan, Adeline Chia, Iain Beehuat Tan, Kamini Kunasegaran, Qin Xuan Chua, Mohammad Yazid Abdad, Aven Shan Hua Ng, Shawn Vasoo, Julian Xiao-Li Ang, Mao Sheng Lee, Louisa Sun, Jinyan Fang, Feng Zhu, Alex R Cook, Tar Choon Aw, Jingxiang Huang, Clarence Tam, Fong Sin Lee, Hannah Clapham, Enan Jun-Kang Goh, Monica Socheata Suor Peou, Shiow Pin Tan, Siew Kim Ong, Lin-Fa Wang, Antonio Bertoletti, Li Yang Hsu, Biauw Chi Ong

Journal: Emerg Microbes Infect

PubMed ID: 34709140

Doi: 10.1080/22221751.2021.1999777

Microbial synthesis of 4-hydroxybenzoic acid from renewable feedstocks

Authors: Yueyang Chen, Yufen Chen, Lijun Liu, Yang Zhang, Jifeng Yuan

Journal: Food Chem (Oxf)

PubMed ID: 35415641

Doi: 10.1016/j.fochms.2021.100059

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Protection against avian coronavirus conferred by oral vaccination with live bacteria secreting LTB-fused viral proteins

Authors: Avishai Lublin, Chen Katz, Nady Gruzdev, Itamar Yadid, Itai Bloch, Yigal Farnoushi, Luba Simanov, Asaf Berkowitz, Dalia Elyahu, Jacob Pitcovski, Ehud Shahar

Journal: Vaccine

PubMed ID: 34998606

Doi: 10.1016/j.vaccine.2021.12.053

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SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells

Authors: Jinliang Wang, Guan Yang, Xinxin Wang, Zhiyuan Wen, Lei Shuai, Jie Luo, Chong Wang, Ziruo Sun, Renqiang Liu, Jinying Ge, Xijun He, Ronghong Hua, Xijun Wang, Xiao Yang, Weiye Chen, Gongxun Zhong, Zhigao Bu

Journal: Cell Discov

PubMed ID: 34903715

Doi: 10.1038/s41421-021-00357-z

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A vesicular stomatitis virus-based prime-boost vaccination strategy induces potent and protective neutralizing antibodies against SARS-CoV-2

Authors: Gyoung Nyoun Kim, Jung-Ah Choi, Kunyu Wu, Nasrin Saeedian, Eunji Yang, Hayan Park, Sun-Je Woo, Gippeum Lim, Seong-Gyu Kim, Su-Kyeong Eo, Hoe Won Jeong, Taewoo Kim, Jae-Hyung Chang, Sang Hwan Seo, Na Hyung Kim, Eunsil Choi, Seungho Choo, Sangkyun Lee, Andrew Winterborn, Yue Li, Kate Parham, Justin M Donovan, Brock Fenton, Jimmy D Dikeakos, Gregory A Dekaban, S M Mansour Haeryfar, Ryan M Troyer, Eric J Arts, Stephen D Barr, Manki Song, C Yong Kang

Journal: PLoS Pathog

PubMed ID: 34914812

Doi: 10.1371/journal.ppat.1010092

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Comprehensive Analysis and Biological Characterization of Venom Components from Solitary Scoliid Wasp

Authors: Carlos Alberto-Silva, Fernanda Calheta Vieira Portaro, Roberto Tadashi Kodama, Halyne Queiroz Pantaleão, Hidetoshi Inagaki, Ken-Ichi Nihei, Katsuhiro Konno

Journal: Toxins (Basel)

PubMed ID: 34941722

Doi: 10.3390/toxins13120885

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Overproduction of medicinal ergot alkaloids based on a fungal platform

Authors: Yongpeng Yao, Wei Wang, Wenyu Shi, Rui Yan, Jun Zhang, Guangzheng Wei, Ling Liu, Yongsheng Che, Chunyan An, Shu-Shan Gao

Journal: Metab Eng

PubMed ID: 34902590

Doi: 10.1016/j.ymben.2021.12.002

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Construction, expression, purification, characterization, and structural analysis of microbial transglutaminase variants

Authors: Xiaoping Song, Hefang Sheng, Yueqiao Zhou, Yin Yu, Yingjiao He, Zihan Wang

Journal: Biotechnol Appl Biochem

PubMed ID: 34894362

Doi: 10.1002/bab.2298

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Edaravone Improves the Post-traumatic Brain Injury Dysfunction in Learning and Memory by Modulating Nrf2/ARE Signal Pathway

Authors: Xiushan Li, Jing Yu, Dongzhou Ma, Xuehui Weng

Journal: Clinics (Sao Paulo)

PubMed ID: 34878029

Doi: 10.6061/clinics/2021/e3131

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Biomaterial-mediated presentation of wnt5a mimetic ligands enhances chondrogenesis and metabolism of stem cells by activating non-canonical Wnt signaling

Authors: Yingrui Deng, Xiaoting Zhang, Rui Li, Zhuo Li, Boguang Yang, Peng Shi, Honglu Zhang, Chunming Wang, Chunyi Wen, Gang Li, Liming Bian

Journal: Biomaterials

PubMed ID: 34959028

Doi: 10.1016/j.biomaterials.2021.121316

Products & Services: Proteins, Expression, Isolation and Analysis

Tanshinone IIA sodium sulfonate attenuates inflammation by upregulating circ-Sirt1 and inhibiting the entry of NF-κB into the nucleus

Authors: Jiao Lan, Ke Li, Austin Gresham, Jifei Miao

Journal: Eur J Pharmacol

PubMed ID: 34896110

Doi: 10.1016/j.ejphar.2021.174693

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Developing a secretory AcGFP1-based IRES expression system for efficient production of mammalian recombinant proteins

Authors: Zhongcheng Zou, Matthew Spencer, Peter D Sun

Journal: Protein Expr Purif

PubMed ID: 34920134

Doi: 10.1016/j.pep.2021.106029

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COVID-19 mRNA booster vaccines elicit strong protection against SARS-CoV-2 Omicron variant in patients with cancer

Authors: Cong Zeng, John P Evans, Karthik Chakravarthy, Panke Qu, Sarah Reisinger, No-Joon Song, Mark P Rubinstein, Peter G Shields, Zihai Li, Shan-Lu Liu

Journal: Cancer Cell

PubMed ID: 34986328

Doi: 10.1016/j.ccell.2021.12.014

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Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

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CASP5 and CR1 as potential biomarkers for Kawasaki disease: an Integrated Bioinformatics-Experimental Study

Authors: Yazdan Rahmati, Hasan Mollanoori, Sajad Najafi, Sajjad Esmaeili, Mohammad Reza Alivand

Journal: BMC Pediatr

PubMed ID: 34895171

Doi: 10.1186/s12887-021-03003-5

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Identification and Characterization of a Novel Plasmid-Encoded Laccase-Like Multicopper Oxidase from sp BF15 Isolated from an On-Farm Bio-Purification System

Authors: María Carla Martini, Francesca Berini, Luka Ausec, Carmine Casciello, Carolina Vacca, Mariano Pistorio, Antonio Lagares, Ines Mandic-Mulec, Flavia Marinelli, María Florencia Del Papa

Journal: Food Technol Biotechnol

PubMed ID: 35136375

Doi: 10.17113/ftb.59.04.21.7253

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Critical residues for proteolysis activity of maize chlorotic dwarf virus (MCDV) 3C-like protease and comparison of activity of orthologous waikavirus proteases

Authors: Lucy R Stewart, Matthew Willman, DeeMarie Marty, Anna Emmick Cole, Kristen Willie

Journal: Virology

PubMed ID: 34998226

Doi: 10.1016/j.virol.2021.12.008

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Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner

Authors: Khushwant S Bhullar, Fatemeh Ashkar, Jianping Wu

Journal: Food Chem (Oxf)

PubMed ID: 35415678

Doi: 10.1016/j.fochms.2021.100069

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Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model

Authors: Murad Alahdal, Rongxiang Huang, Li Duan, Deng Zhiqin, Ouyang Hongwei, Wencui Li, Daping Wang

Journal: Front Immunol

PubMed ID: 34956209

Doi: 10.3389/fimmu.2021.781185

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Engineering a Pseudo-26-kDa Glutathione Transferase from / for Structure, Kinetics, and Ligandin Studies

Authors: Neo Padi, Blessing Oluebube Akumadu, Olga Faerch, Chinyere Aloke, Vanessa Meyer, Ikechukwu Achilonu

Journal: Biomolecules

PubMed ID: 34944488

Doi: 10.3390/biom11121844

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SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice NF-ĸB Activation

Authors: Jie Xia, Wenqi Tang, Jiangmei Wang, Dengming Lai, Qi Xu, Ruoqiong Huang, Yaoqin Hu, Xiaojue Gong, Jiajie Fan, Qiang Shu, Jianguo Xu

Journal: Front Immunol

PubMed ID: 34950152

Doi: 10.3389/fimmu.2021.791753

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SARS-CoV-2 seroprevalence, seroconversion and neutralizing antibodies in a systemic lupus erythematosus cohort and comparison to controls

Authors: Hannah R Mathew, May Y Choi, Katherine Buhler, Xenia Gukova, Francesca S Cardwell, Heather Waldhauser, Ann E Clarke, Marvin J Fritzler

Journal: Lupus

PubMed ID: 34874781

Doi: 10.1177/09612033211063793

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The impact of benzo[a]pyrene on murine allergic airway inflammation via epigenetic remodeling

Authors: Xihua Wang, Shuyuan Guan, Lingbin Sun, Zhongliang Dai

Journal: Environ Toxicol Pharmacol

PubMed ID: 34883242

Doi: 10.1016/j.etap.2021.103782

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Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

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Comprehensive Genome-Wide Identification and Transcript Profiling of GABA Pathway Gene Family in Apple ()

Authors: Qingbo Zheng, Shenghui Su, Zhe Wang, Yongzhang Wang, Xiaozhao Xu

Journal: Genes (Basel)

PubMed ID: 34946926

Doi: 10.3390/genes12121973

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An immunochromatographic assay utilizing magnetic nanoparticles to detect major peanut allergen Ara h 1 in processed foods

Authors: Hsin-Yi Yin, Yi-Ting Li, Wen-Che Tsai, Hong-Yu Dai, Hsiao-Wei Wen

Journal: Food Chem

PubMed ID: 34952385

Doi: 10.1016/j.foodchem.2021.131844

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Hydroxysafflor yellow A inhibits the proliferation, migration, and invasion of colorectal cancer cells through the PPARγ/PTEN/Akt signaling pathway

Authors: Dan Su, Chunye Lv

Journal: Bioengineered

PubMed ID: 34889713

Doi: 10.1080/21655979.2021.2009965

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Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma

Authors: Liya Wang, Lucia Unger, Hanan Sharif, Staffan Eriksson, Vinzenz Gerber, Henrik Rönnberg

Journal: BMC Mol Cell Biol

PubMed ID: 34906077

Doi: 10.1186/s12860-021-00399-x

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Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma

Authors: Liya Wang, Lucia Unger, Hanan Sharif, Staffan Eriksson, Vinzenz Gerber, Henrik Rönnberg

Journal: BMC Mol Cell Biol

PubMed ID: 34906077

Doi: 10.1186/s12860-021-00399-x

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A periplasmic cupredoxin with a green CuT15 center is involved in bacterial copper tolerance

Authors: Anne Durand, Mélanie Fouesnard, Marie-Line Bourbon, Anne-Soisig Steunou, Elisabeth Lojou, Pierre Dorlet, Soufian Ouchane

Journal: Metallomics

PubMed ID: 34791351

Doi: 10.1093/mtomcs/mfab067

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miR‑30a‑5p induces the adipogenic differentiation of bone marrow mesenchymal stem cells by targeting FAM13A/Wnt/β‑catenin signaling in aplastic anemia

Authors: Enbo Wang, Yunyan Zhang, Rongmei Ding, Xiaohua Wang, Shumin Zhang, Xinghua Li

Journal: Mol Med Rep

PubMed ID: 34821370

Doi: 10.3892/mmr.2021.12543

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Incomplete radiofrequency ablation induced chemoresistance by up-regulating heat shock protein 70 in hepatocellular carcinoma

Authors: Fuan Wang, Chuan Xu, Guiling Li, Penghua Lv, Jianping Gu

Journal: Exp Cell Res

PubMed ID: 34801560

Doi: 10.1016/j.yexcr.2021.112910

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Crystal structure of Aedes aegypti trypsin inhibitor in complex with μ-plasmin reveals role for scaffold stability in Kazal-type serine protease inhibitor

Authors: Varsha Ashok Walvekar, Karthik Ramesh, Chacko Jobichen, Muthu Kannan, J Sivaraman, R Manjunatha Kini, Yu Keung Mok

Journal: Protein Sci

PubMed ID: 34800067

Doi: 10.1002/pro.4245

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Relative Ratios of Human Seasonal Coronavirus Antibodies Predict the Efficiency of Cross-Neutralization of SARS-CoV-2 Spike Binding to ACE2

Authors: Yannick Galipeau, Vinayakumar Siragam, Geneviève Laroche, Erika Marion, Matthew Greig, Michaeline McGuinty, Ronald A Booth, Yves Durocher, Miroslava Cuperlovic-Culf, Steffany A L Bennett, Angela M Crawley, Patrick M Giguère, Curtis Cooper, Marc-André Langlois

Journal: EBioMedicine

PubMed ID: 34861490

Doi: 10.1016/j.ebiom.2021.103700

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The Marine Neurotoxin Brevetoxin (PbTx-2) Inhibits and Mammalian Thioredoxin Reductases by Targeting Different Residues

Authors: Ricardo Colon, Michelle Wheater, Emily J Joyce, Emma J Ste Marie, Robert J Hondal, Kathleen S Rein

Journal: J Nat Prod

PubMed ID: 34752085

Doi: 10.1021/acs.jnatprod.1c00795

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Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs

Authors: Sophie M-C Gobeil, Benjamin G Bobay, Praveen R Juvvadi, D Christopher Cole, Joseph Heitman, William J Steinbach, Ronald A Venters, Leonard D Spicer

Journal: MBio

PubMed ID: 34809463

Doi: 10.1128/mBio.03000-21

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Multilayered regulation of autophagy by the Atg1 kinase orchestrates spatial and temporal control of autophagosome formation

Authors: Anne Schreiber, Ben C Collins, Colin Davis, Radoslav I Enchev, Angie Sedra, Rocco D'Antuono, Ruedi Aebersold, Matthias Peter

Journal: Mol Cell

PubMed ID: 34798055

Doi: 10.1016/j.molcel.2021.10.024

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Hydrophobicity-tuned anion responsiveness underlies endosomolytic cargo delivery mediated by amphipathic vehicle peptides

Authors: Xiaolong Chen, Hanjie Liu, Ang Li, Shuangshuang Ji, Hao Fei

Journal: J Biol Chem

PubMed ID: 34736897

Doi: 10.1016/j.jbc.2021.101364

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Heterotypic Amyloid β interactions facilitate amyloid assembly and modify amyloid structure

Authors: Katerina Konstantoulea, Patricia Guerreiro, Meine Ramakers, Nikolaos Louros, Liam D Aubrey, Bert Houben, Emiel Michiels, Matthias De Vleeschouwer, Yulia Lampi, Luís F Ribeiro, Joris de Wit, Wei-Feng Xue, Joost Schymkowitz, Frederic Rousseau

Journal: EMBO J

PubMed ID: 34842295

Doi: 10.15252/embj.2021108591

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TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease

Authors: Christian B Lindstad, Alisa E Dewan, Jorunn Stamnaes, Ludvig M Sollid, M Fleur du Pré

Journal: PLoS ONE

PubMed ID: 34731200

Doi: 10.1371/journal.pone.0259082

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T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study

Authors: Adrienn Angyal, Stephanie Longet, Shona C Moore, Rebecca P Payne, Adam Harding, Tom Tipton, Patpong Rongkard, Mohammad Ali, Luisa M Hering, Naomi Meardon, James Austin, Rebecca Brown, Donal Skelly, Natalie Gillson, Sue L Dobson, Andrew Cross, Gurjinder Sandhar, Jonathan A Kilby, Jessica K Tyerman, Alexander R Nicols, Jarmila S Spegarova, Hema Mehta, Hailey Hornsby, Rachel Whitham, Christopher P Conlon, Katie Jeffery, Philip Goulder, John Frater, Christina Dold, Matthew Pace, Ane Ogbe, Helen Brown, M Azim Ansari, Emily Adland, Anthony Brown, Meera Chand, Adrian Shields, Philippa C Matthews, Susan Hopkins, Victoria Hall, William James, Sarah L Rowland-Jones, Paul Klenerman, Susanna Dunachie, Alex Richter, Christopher J A Duncan, Eleanor Barnes, Miles Carroll, Lance Turtle, Thushan I de Silva

Journal: Lancet Microbe

PubMed ID: 34778853

Doi: 10.1016/S2666-5247(21)00275-5

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Identification of immunogenic MHC class II human HER3 peptides that mediate anti-HER3 CD4+ Th1 responses and potential use as a cancer vaccine

Authors: Amrita Basu, Gabriella K Albert, Sabrina Awshah, Jashodeep Datta, Krithika N Kodumudi, Corey Gallen, Amber Beyer, Keiran S M Smalley, Paulo C Rodriguez, Derek R Dukett, Peter A Forsyth, Aixa Soyano, Gary K Koski, Ricardo Lima Barros Costa, Heather Han, Hatem Soliman, Marie Catherine Lee, Pawel Kalinski, Brian J Czerniecki

Journal: Cancer Immunol Res

PubMed ID: 34785506

Doi: 10.1158/2326-6066.CIR-21-0454

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Peptide-coating 2D and small chemical molecules prolong the passage of porcine spermatogonia stem cells

Authors: Ying Zhang, Camila Bruna de Lima, Zhe Zhou, Qiaoyan Shen, Zhenshuo Zhu, Jinlian Hua

Journal: Reprod Domest Anim

PubMed ID: 34748668

Doi: 10.1111/rda.14042

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Suppression of a Novel Vitellogenesis-Inhibiting Hormone Significantly Increases Ovarian Vitellogenesis in the Black Tiger Shrimp,

Authors: Phaivit Laphyai, Thanapong Kruangkum, Charoonroj Chotwiwatthanakun, Wanita Semchuchot, Prawporn Thaijongrak, Prasert Sobhon, Pei-San Tsai, Rapeepun Vanichviriyakit

Journal: Front Endocrinol (Lausanne)

PubMed ID: 34867802

Doi: 10.3389/fendo.2021.760538

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Neoantigen Dendritic Cell Vaccination Combined with Anti-CD38 and CpG Elicits Anti-Tumor Immunity against the Immune Checkpoint Therapy-Resistant Murine Lung Cancer Cell Line LLC1

Authors: Changbo Sun, Koji Nagaoka, Yukari Kobayashi, Hidewaki Nakagawa, Kazuhiro Kakimi, Jun Nakajima

Journal: Cancers (Basel)

PubMed ID: 34771674

Doi: 10.3390/cancers13215508

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Engineering of for 24-Methylene-Cholesterol Production

Authors: Jiao Yang, Changfu Li, Yansheng Zhang

Journal: Biomolecules

PubMed ID: 34827708

Doi: 10.3390/biom11111710

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High-Throughput On-Chip Human Mesenchymal Stromal Cell Potency Prediction

Authors: Rebecca S Schneider, Alexandra C Vela, Evelyn Kendall Williams, Karen E Martin, Wilbur A Lam, Andrés J García

Journal: Adv Healthc Mater

PubMed ID: 34725948

Doi: 10.1002/adhm.202101995

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The flagellin of Vibrio parahaemolyticus induces the inflammatory response of Tetraodon nigroviridis through TLR5M

Authors: Xue Yu, Songze Gao, Jiachang Xu, Yulin Zhao, Yuyou Lu, Niuniu Deng, Haoran Lin, Yong Zhang, Danqi Lu

Journal: Fish Shellfish Immunol

PubMed ID: 34737057

Doi: 10.1016/j.fsi.2021.10.024

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HO Functions as a Downstream Signal of IAA to Mediate HS-Induced Chilling Tolerance in Cucumber

Authors: Xiaowei Zhang, Yanyan Zhang, Chenxiao Xu, Kun Liu, Huangai Bi, Xizhen Ai

Journal: Int J Mol Sci

PubMed ID: 34884713

Doi: 10.3390/ijms222312910

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sp nov, isolated from Arctic tundra soil, and emended descriptions of , and

Authors: Yongping Zhang, Xiaoya Peng, Kun Qin, Jia Liu, Qiang Xu, Jingjing Niu, Yanyan Zheng, Fang Peng

Journal: Int J Syst Evol Microbiol

PubMed ID: 34846279

Doi: 10.1099/ijsem.0.005103

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Pharmacokinetic Assessment of Rottlerin from Using a Highly Sensitive Liquid Chromatography-Tandem Mass Spectrometry-Based Bioanalytical Method

Authors: Diksha Manhas, Abhishek Gour, Nivedita Bhardwaj, Deepak K Sharma, Kuhu Sharma, Bhavna Vij, Shreyans K Jain, Gurdarshan Singh, Utpal Nandi

Journal: ACS Omega

PubMed ID: 34901612

Doi: 10.1021/acsomega.1c04266

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Geminin is essential for DNA re-replication in the silk gland cells of silkworms

Authors: Tai-Hang Liu, Xiao-Long Dong, Peng Chen, Qian Zhang, Xiao-Lin Zhou, Cheng Lu, Min-Hui Pan

Journal: Exp Cell Res

PubMed ID: 34843715

Doi: 10.1016/j.yexcr.2021.112951

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Toxicological Evaluation of a Probiotic-Based Delivery System for P8 Protein as an Anti-Colorectal Cancer Drug

Authors: Byung Chull An, Yeo-Sang Yoon, Ho Jin Park, Sangkyun Park, Tai Yeub Kim, Jun Young Ahn, Daebeom Kwon, Oksik Choi, Jin Young Heo, Yongku Ryu, Joong-Hyun Kim, Heejong Eom, Myung Jun Chung

Journal: Drug Des Devel Ther

PubMed ID: 34866901

Doi: 10.2147/DDDT.S319930

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Preparation of multiplexed control materials for cancer mutation analysis by genome editing in GM12878 cells

Authors: Guigao Lin, Kuo Zhang, Yanxi Han, Rongxue Peng, Jinming Li

Journal: J Clin Lab Anal

PubMed ID: 34811797

Doi: 10.1002/jcla.24139

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Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine

Authors: Yajuan Zhang, Hua Yu, Jie Zhang, Hong Gao, Siyao Wang, Shuxian Li, Ping Wei, Ji Liang, Guanzhen Yu, Xiongjun Wang, Xinxiang Li, Dawei Li, Weiwei Yang

Journal: J Clin Invest

PubMed ID: 34720086

Doi: 10.1172/JCI146187

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ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling

Authors: Beibei Wu, Arunachalam Ramaiah, Gustavo Garcia, Spyridon Hasiakos, Vaithilingaraja Arumugaswami, Sonal Srikanth

Journal: J Immunol

PubMed ID: 34819389

Doi: 10.4049/jimmunol.2100742

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Trichinella spiralis: Knockdown of gamma interferon inducible lysosomal thiol reductase (GILT) results in the reduction of worm burden

Authors: Hong Fei, Muhammad Ali-Ul-Husnain Naqvi, Sana Zahra Naqvi, Lixin Xu, Xiaokai Song, Xiangrui Li, Ruofeng Yan

Journal: PLoS Negl Trop Dis

PubMed ID: 34847145

Doi: 10.1371/journal.pntd.0009958

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Key carboxylate residues for iron transit through the prokaryotic ferritin Ftn

Authors: Justin M Bradley, Joshua Fair, Andrew M Hemmings, Nick E Le Brun

Journal: Microbiology (Reading)

PubMed ID: 34825885

Doi: 10.1099/mic.0.001105

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Development of a novel promoter engineering-based strategy for creating an efficient para-nitrophenol-mineralizing bacterium

Authors: Kaiyue Huo, Yujie Liu, Rui Huang, Yiting Zhang, Honglu Liu, You Che, Chao Yang

Journal: J Hazard Mater.

PubMed ID: 34753648

Doi: 10.1016/j.jhazmat.2021.127672.

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Neutralization of SARS-CoV-2 Variants in Transplant Recipients After Two and Three Doses of mRNA-1273 Vaccine : Secondary Analysis of a Randomized Trial

Authors: Deepali Kumar, Victor H Ferreira, Victoria G Hall, Queenie Hu, Reuben Samson, Terrance Ku, Matthew Ierullo, Beata Majchrzak-Kita, George Tomlinson, Anne-Claude Gingras, Atul Humar

Journal: Ann Intern Med

PubMed ID: 34807716

Doi: 10.7326/M21-3480

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Author Correction: Disulfide-compatible phage-assisted continuous evolution in the periplasmic space

Authors: Mary S Morrison, Tina Wang, Aditya Raguram, Colin Hemez, David R Liu

Journal: Nat Commun

PubMed ID: 34789771

Doi: 10.1038/s41467-021-27102-0

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The Flawed Science of Antibody Testing for SARS-CoV-2 Immunity

Authors:

Journal: JAMA

PubMed ID: 34673883

Doi: 10.1001/jama.2021.18919

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Bunyavirus SFTSV exploits autophagic flux for viral assembly and egress

Authors: Jia-Min Yan, Wen-Kang Zhang, Li-Na Yan, Yong-Jun Jiao, Chuan-Min Zhou, Xue-Jie Yu

Journal: Autophagy

PubMed ID: 34747299

Doi: 10.1080/15548627.2021.1994296

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Porcine Epidemic Diarrhea Virus Envelope Protein Blocks SLA-DR Expression in Barrow-Derived Dendritic Cells by Inhibiting Promoters Activation

Authors: Jie Wang, Yajing Wang, Bing Liu, Yunwei He, Zhiwei Li, Qin Zhao, Yuchen Nan, Chunyan Wu

Journal: Front Immunol

PubMed ID: 34858400

Doi: 10.3389/fimmu.2021.741425

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Structures of the HER2-HER3-NRG1β complex reveal a dynamic dimer interface

Authors: Devan Diwanji, Raphael Trenker, Tarjani M Thaker, Feng Wang, David A Agard, Kliment A Verba, Natalia Jura

Journal: Nature

PubMed ID: 34759323

Doi: 10.1038/s41586-021-04084-z

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Aggregation and the Intrinsic Structural Disorder of Dipeptide Repeat Peptides of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Characterized by NMR

Authors: Bankala Krishnarjuna, Magdalena I Ivanova, Ayyalusamy Ramamoorthy

Journal: J Phys Chem B

PubMed ID: 34751579

Doi: 10.1021/acs.jpcb.1c08149

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Probing Insulin Sensitivity with Metabolically Competent Human Stem Cell-Derived White Adipose Tissue Microphysiological Systems

Authors: Lin Qi, Peter-James H Zushin, Ching-Fang Chang, Yue Tung Lee, Diana L Alba, Suneil K Koliwad, Andreas Stahl

Journal: Small

PubMed ID: 34761526

Doi: 10.1002/smll.202103157

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YAP Promotes Cell Proliferation and Stemness Maintenance of Porcine Muscle Stem Cells under High-Density Condition

Authors: Zheng Liu, Ling Lin, Haozhe Zhu, Zhongyuan Wu, Xi Ding, Rongrong Hu, Yichen Jiang, Changbo Tang, Shijie Ding, Renpeng Guo

Journal: Cells

PubMed ID: 34831292

Doi: 10.3390/cells10113069

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Chromium induced neurotoxicity by altering metabolism in zebrafish larvae

Authors: Yawen Xu, Li Wang, Jun Zhu, Ping Jiang, Zhan Zhang, Lei Li, Qian Wu

Journal: Ecotoxicol Environ Saf

PubMed ID: 34781135

Doi: 10.1016/j.ecoenv.2021.112983

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A venom protein of ectoparasitoid Pachycrepoideus vindemiae, PvG6PDH, contributes to parasitism by inhibiting host glucose-6-phosphate metabolism

Authors: Lei Yang, Liming Qiu, Qi Fang, Shaoying Wu, Gongyin Ye

Journal: Insect Sci

PubMed ID: 34724344

Doi: 10.1111/1744-7917.12935

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Development of a Self-Adjuvanting, Cross-Protective, Stable Intranasal Recombinant Vaccine for Shigellosis

Authors: Namrata Baruah, Nadim Ahamad, Suhrid Maiti, Debaki R Howlader, Ushasi Bhaumik, Vinod V Patil, Manoj K Chakrabarti, Hemanta Koley, Dhirendra S Katti

Journal: ACS Infect Dis

PubMed ID: 34734708

Doi: 10.1021/acsinfecdis.1c00345

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Improved production of the non-native cofactor F in Escherichia coli

Authors: Mihir V Shah, Hadi Nazem-Bokaee, James Antoney, Suk Woo Kang, Colin J Jackson, Colin Scott

Journal: Sci Rep

PubMed ID: 34741069

Doi: 10.1038/s41598-021-01224-3

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A Histoplasma capsulatum Lipid Metabolic Map Identifies Antifungal Targets

Authors: Daniel Zamith-Miranda, Heino M Heyman, Meagan C Burnet, Sneha P Couvillion, Xueyun Zheng, Nathalie Munoz, William C Nelson, Jennifer E Kyle, Erika M Zink, Karl K Weitz, Kent J Bloodsworth, Geremy Clair, Jeremy D Zucker, Jeremy R Teuton, Samuel H Payne, Young-Mo Kim, Morayma Reyes Gil, Erin S Baker, Erin L Bredeweg, Joshua D Nosanchuk, Ernesto S Nakayasu

Journal: MBio

PubMed ID: 34809453

Doi: 10.1128/mBio.02972-21

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