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Genomic distribution of signal transducer and activator of transcription (STAT) family in colorectal cancer

Authors: Yanping Hu, Yifen Shen, Yang Zhao, Ying Tang, Chao Liu, Yongchun Gu, Tao Yang, Yihang Shen

Journal: Hum Cell

PubMed ID: 36284066

Doi: 10.1007/s13577-022-00815-0

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Embracing enzyme promiscuity with activity-based compressed biosensing

Authors: Brandon Alexander Holt, Hong Seo Lim, Anirudh Sivakumar, Hathaichanok Phuengkham, Melanie Su, McKenzie Tuttle, Yilin Xu, Haley Liakakos, Peng Qiu, Gabriel A Kwong

Journal: Cell Rep Methods

PubMed ID: 36814844

Doi: 10.1016/j.crmeth.2022.100372

Products & Services: Gene Synthesis

The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection

Authors: Mathew P Kirby, Ciara Stevenson, Liam J Worrall, Yihang Chen, Christina Young, Jisoo Youm, Natalie C J Strynadka, Douglas W Allan, Eric Jan

Journal: J Virol

PubMed ID: 35019716

Doi: 10.1128/JVI.01330-21

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In silico, in vitro and in vivo safety evaluation of Limosilactobacillus reuteri strains ATCC PTA-126787 & ATCC PTA-126788 for potential probiotic applications

Authors: Dharanesh Gangaiah, Shrinivasrao P Mane, Nilesh R Tawari, Nallakannu Lakshmanan, Valerie Ryan, Alyssa Volland, Dwi Susanti, Milind Patel, Abraham Abouzeid, Emily B Helmes, Arvind Kumar

Journal: PLoS ONE

PubMed ID: 35081129

Doi: 10.1371/journal.pone.0262663

Products & Services: DNA Sequencing

Catalase () Gene Family in Wheat ( L): Evolution, Expression Pattern and Function Analysis

Authors: Yan Zhang, Lanjie Zheng, Liu Yun, Li Ji, Guanhui Li, Manchun Ji, Yong Shi, Xu Zheng

Journal: Int J Mol Sci

PubMed ID: 35008967

Doi: 10.3390/ijms23010542

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SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability

Authors: Manami Hiraiwa, Kazuya Fukasawa, Takashi Iezaki, Hemragul Sabit, Tetsuhiro Horie, Kazuya Tokumura, Sayuki Iwahashi, Misato Murata, Masaki Kobayashi, Akane Suzuki, Gyujin Park, Katsuyuki Kaneda, Tomoki Todo, Atsushi Hirao, Mitsutoshi Nakada, Eiichi Hinoi

Journal: Commun Biol

PubMed ID: 35017630

Doi: 10.1038/s42003-021-02950-0

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Preclinical Evaluation of Chicken Egg Yolk Antibody (IgY) Anti-RBD Spike SARS-CoV-2-A Candidate for Passive Immunization against COVID-19

Authors: Hendris Wongso, Isa Mahendra, Wyanda Arnafia, Idar Idar, Muhammad Yusuf, Arifudin Achmad, Holis A Holik, Ahmad Kurniawan, Iim Halimah, Maula E Sriyani, Teguh H A Wibawa, Muhamad B Febrian, Yanuar Setiadi, Eva M Widyasari, Isti Daruwati, Crhisterra E Kusumaningrum, Toto Subroto

Journal: Vaccines (Basel)

PubMed ID: 35062789

Doi: 10.3390/vaccines10010128

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Engineering His-Tagged Senecavirus A for One-Step Purification of Viral Antigens

Authors: Junhao Fan, Peiyu Xiao, Dongni Kong, Xinran Liu, Liang Meng, Tongqing An, Xuehui Cai, Haiwei Wang, Li Yu

Journal: Vaccines (Basel)

PubMed ID: 35214628

Doi: 10.3390/vaccines10020170

Products & Services: Recombinant Antibody Expression

Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells

Authors: Lakshana Sreenivasan, Ling Vicky Li, Pascal Leclair, Chinten James Lim

Journal: Cells

PubMed ID: 35159191

Doi: 10.3390/cells11030381

Products & Services: Recombinant Proteins

OsMYB103 is essential for tapetum degradation in rice

Authors: Ting Lei, Lisha Zhang, Ping Feng, Yang Liu, Wuzhong Yin, Lina Shang, Guanghua He, Nan Wang

Journal: Theor Appl Genet

PubMed ID: 35018498

Doi: 10.1007/s00122-021-04007-6

Products & Services: Proteins, Expression, Isolation and Analysis

Exogenous Production of N-acetylmuramyl-L Alanine Amidase (LysM2) from Siphoviridae Phage Affecting Anti-Gram-Negative Bacteria: Evaluation of Its Structure and Function

Authors: Morteza Miri, Sepideh Yazdianpour, Shamsozoha Abolmaali, Shakiba Darvish Alipour Astaneh

Journal: Avicenna J Med Biotechnol

PubMed ID: 35509364

Doi: 10.18502/ajmb.v14i1.8169

Products & Services: DNA Sequencing

Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide

Authors: Eva Pauwels, Becky Provinciael, Anita Camps, Enno Hartmann, Kurt Vermeire

Journal: Int J Mol Sci

PubMed ID: 35054769

Doi: 10.3390/ijms23020584

Products & Services: Proteins, Expression, Isolation and Analysis

Dimensionless parameter predicts bacterial prodrug success

Authors: Brandon Alexander Holt, McKenzie Tuttle, Yilin Xu, Melanie Su, Joachim J Røise, Xioajian Wang, Niren Murthy, Gabriel A Kwong

Journal: Mol Syst Biol

PubMed ID: 35005851

Doi: 10.15252/msb.202110495

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Immunogenicity of a recombinant VSV-Vectored SARS-CoV vaccine induced robust immunity in rhesus monkeys after single-dose immunization

Authors: Dan Shan, Xiaoyan Tang, Renqiang Liu, Dan Pan, Xijun Wang, Jinying Ge, Zhiyuan Wen, Zhigao Bu

Journal: Virol Sin

PubMed ID: 35234625

Doi: 10.1016/j.virs.2022.01.002

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Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors

Authors: Daichao Wu, Alexander Kolesnikov, Rui Yin, Johnathan D Guest, Ragul Gowthaman, Anton Shmelev, Yana Serdyuk, Dmitry V Dianov, Grigory A Efimov, Brian G Pierce, Roy A Mariuzza

Journal: Nat Commun

PubMed ID: 35013235

Doi: 10.1038/s41467-021-27669-8

Products & Services: DNA Sequencing

Selective Coimmobilization of His-Tagged Enzymes on Yttrium-Stabilized Zirconia-Based Membranes for Continuous Asymmetric Bioreductions

Authors: Daniel Andrés-Sanz, Eleftheria Diamanti, Desirè Di Silvo, Jonas Gurauskis, Fernando López-Gallego

Journal: ACS Appl Mater Interfaces

PubMed ID: 35020352

Doi: 10.1021/acsami.1c20738

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Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity

Authors: Xiufei Chen, Wenjie Zhou, Ren-Hua Song, Shuang Liu, Shu Wang, Yujia Chen, Chao Gao, Chenxi He, Jianxiong Xiao, Lei Zhang, Tianxiang Wang, Peng Liu, Kunlong Duan, Zhouli Cheng, Chen Zhang, Jinye Zhang, Yiping Sun, Felix Jackson, Fei Lan, Yun Liu, Yanhui Xu, Justin Jong-Leong Wong, Pu Wang, Hui Yang, Yue Xiong, Tong Chen, Yan Li, Dan Ye

Journal: Sci Adv

PubMed ID: 35080973

Doi: 10.1126/sciadv.abl5220

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Impairing RAGE signaling promotes survival and limits disease pathogenesis following SARS-CoV-2 infection in mice

Authors: Forrest Jessop, Benjamin Schwarz, Dana Scott, Lydia M Roberts, Eric Bohrnsen, John R Hoidal, Catharine M Bosio

Journal: JCI Insight

PubMed ID: 35076028

Doi: 10.1172/jci.insight.155896

Products & Services: Proteins, Expression, Isolation and Analysis

Myricetin Allosterically Inhibits the Dengue NS2B-NS3 Protease by Disrupting the Active and Locking the Inactive Conformations

Authors: Mei Dang, Liangzhong Lim, Amrita Roy, Jianxing Song

Journal: ACS Omega

PubMed ID: 35097276

Doi: 10.1021/acsomega.1c05569

Products & Services: Recombinant Proteins

A combination of multiple autoantibodies is associated with the risk of Alzheimer's disease and cognitive impairment

Authors: Sung-Mi Shim, Young Ho Koh, Jong-Hoon Kim, Jae-Pil Jeon

Journal: Sci Rep

PubMed ID: 35079008

Doi: 10.1038/s41598-021-04556-2

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Protein Interactome Analysis of the Type IX Secretion System Identifies PorW as the Missing Link between the PorK/N Ring Complex and the Sov Translocon

Authors: Dhana G Gorasia, Ignacio Lunar Silva, Catherine A Butler, Maïalène Chabalier, Thierry Doan, Eric Cascales, Paul D Veith, Eric C Reynolds

Journal: Microbiol Spectr

PubMed ID: 35019767

Doi: 10.1128/spectrum.01602-21

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Multifunctional liposomal nanostructure-mediated siRNA/bortezomib co-delivery for SHARP1 knockdown in MLL-AF6 acute myeloid leukemia

Authors: Sameh A Mohammed, Yang Ju

Journal: Biomater Adv

PubMed ID: 35577689

Doi: 10.1016/j.msec.2022.112663

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EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells

Authors: Ying Li, Jiuxiang Feng, Yue Bian, Wei Cheng, Chong Qiao

Journal: Folia Histochem Cytobiol

PubMed ID: 35038162

Doi: 10.5603/FHC.a2022.0001

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Control of subunit stoichiometry in single-chain MspA nanopores

Authors: Mikhail Pavlenok, Luning Yu, Dominik Herrmann, Meni Wanunu, Michael Niederweis

Journal: Biophys J

PubMed ID: 35101416

Doi: 10.1016/j.bpj.2022.01.022

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Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models

Authors: Aviral Kumar, Amarnath Singam, Guruprasadh Swaminathan, Naresh Killi, Naveen Kumar Tangudu, Jedy Jose, Rathna Gundloori Vn, Lekha Dinesh Kumar

Journal: Nanoscale

PubMed ID: 34913453

Doi: 10.1039/d1nr04411g

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Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging

Authors: Manning Y Huang, Meenakshi B Joshi, Michael J Boucher, Sujin Lee, Liza C Loza, Elizabeth A Gaylord, Tamara L Doering, Hiten D Madhani

Journal: Genetics

PubMed ID: 34791226

Doi: 10.1093/genetics/iyab180

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Improved myocardial performance in infarcted rat heart by injection of disulfide-cross-linked chitosan hydrogels loaded with basic fibroblast growth factor

Authors: Bo Fu, Xiaobei Wang, Zhengda Chen, Nan Jiang, Zhigang Guo, Yuhui Zhang, Shaopeng Zhang, Xiankun Liu, Li Liu

Journal: J Mater Chem B

PubMed ID: 35014648

Doi: 10.1039/d1tb01961a

Products & Services: Proteins, Expression, Isolation and Analysis

Lipoxin A and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway

Authors: Fen Xu, Jiamin Zhang, Xiaoyan Zhou, Hua Hao

Journal: Exp Cell Res

PubMed ID: 35026282

Doi: 10.1016/j.yexcr.2022.113025

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Molecular Characterization of Mg-Chelatase CHLI Subunit in Pea ( L)

Authors: Cai-Jun Wu, Jie Wang, Jun Zhu, Jing Ren, You-Xin Yang, Tao Luo, Lu-Xi Xu, Qing-Hong Zhou, Xu-Feng Xiao, Yu-Xin Zhou, Sha Luo

Journal: Front Plant Sci

PubMed ID: 35145539

Doi: 10.3389/fpls.2022.821683

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Molecular Characterization of Mg-Chelatase CHLI Subunit in Pea ( L)

Authors: Cai-Jun Wu, Jie Wang, Jun Zhu, Jing Ren, You-Xin Yang, Tao Luo, Lu-Xi Xu, Qing-Hong Zhou, Xu-Feng Xiao, Yu-Xin Zhou, Sha Luo

Journal: Front Plant Sci

PubMed ID: 35145539

Doi: 10.3389/fpls.2022.821683

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The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential

Authors: Lu Wang, Xi Wang, Xiying Lv, Qiushuo Jin, Hongcai Shang, Chih-Chen Wang, Lei Wang

Journal: Redox Biol

PubMed ID: 35077997

Doi: 10.1016/j.redox.2022.102244

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Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test

Authors: Qiao Wang, Lili Feng, Haohai Zhang, Juehua Gao, Changchuin Mao, Esther Landesman-Bollag, Gustavo Mostoslavsky, Justin M Lunderberg, Weina Zheng, Shushun Hao, Wenda Gao

Journal: Antib Ther

PubMed ID: 35146332

Doi: 10.1093/abt/tbac004

Products & Services: Proteins, Expression, Isolation and Analysis

Severity of adverse reactions is associated with T-cell response in mRNA-1273 vaccinated health care workers

Authors: Hanna Klingel, Maike Lauen, Alexander Krüttgen, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223673

Doi: 10.7774/cevr.2022.11.1.121

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Inhibiting L1CAM Reverses Cisplatin Resistance of Triple Negative Breast Cancer Cells by Blocking AKT Signaling Pathway

Authors: Lu-Yao Zhang, Zhi-Xin Shen, Lu Guo

Journal: Cancer Invest

PubMed ID: 35040385

Doi: 10.1080/07357907.2021.2016801

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Solid-Phase Extraction Approaches for Improving Oligosaccharide and Small Peptide Identification with Liquid Chromatography-High-Resolution Mass Spectrometry: A Case Study on Proteolyzed Almond Extract

Authors: Yu-Ping Huang, Randall C Robinson, Fernanda Furlan Goncalves Dias, Juliana Maria Leite Nobrega de Moura Bell, Daniela Barile

Journal: Foods

PubMed ID: 35159490

Doi: 10.3390/foods11030340

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Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3

Authors: Chad S Hewitt, Chittaranjan Das, Daniel P Flaherty

Journal: Biomolecules

PubMed ID: 35053210

Doi: 10.3390/biom12010062

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Protection and Alleviated Inflammation Induced by Virus-like Particle Vaccines Containing MSP-8, MSP-9 and RAP1

Authors: Su-Hwa Lee, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 35214662

Doi: 10.3390/vaccines10020203

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Protection and Alleviated Inflammation Induced by Virus-like Particle Vaccines Containing MSP-8, MSP-9 and RAP1

Authors: Su-Hwa Lee, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 35214662

Doi: 10.3390/vaccines10020203

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Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations

Authors: Anju Jaiswal, D Dash, Rashmi Singh

Journal: Toxicol Appl Pharmacol

PubMed ID: 34998855

Doi: 10.1016/j.taap.2021.115861

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Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response

Authors: Satoshi Shimizu, Yoichi Sunagawa, Naruto Hajika, Natsumi Yorimitsu, Yasufumi Katanasaka, Masafumi Funamoto, Yusuke Miyazaki, Nurmila Sari, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto

Journal: Int J Biol Sci

PubMed ID: 35173540

Doi: 10.7150/ijbs.65664

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Heterologous Expression and Functional Characterization of CAP18 from

Authors: Mahla Nikpoor, Azadeh Lohrasbi-Nejad, Jafar Zolala

Journal: Rep Biochem Mol Biol

PubMed ID: 35291606

Doi: 10.52547/rbmb.10.4.622

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Activity-based protein profiling reveals dynamic substrate-specific cellulase secretion by saprotrophic basidiomycetes

Authors: Nicholas G S McGregor, Casper de Boer, Mikhaaeel Santos, Mireille Haon, David Navarro, Sybrin Schroder, Jean-Guy Berrin, Herman S Overkleeft, Gideon J Davies

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 35418096

Doi: 10.1186/s13068-022-02107-z

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GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus

Authors: Nitaya Indrawattana, Pisinee Aiumurai, Nawannaporn Sae-Lim, Watee Seesuay, Onrapak Reamtong, Manas Chongsa-Nguan, Wanpen Chaicumpa, Nitat Sookrung

Journal: Diagnostics (Basel)

PubMed ID: 35054302

Doi: 10.3390/diagnostics12010136

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Core-shell "loading-type" nanomaterials towards: Simultaneous imaging analysis of glutathione and microRNA

Authors: Lin-Lin Lu, Qin Zhang, Yu Gu, Xiang-Ling Li, Jing Jing Xie

Journal: Anal Chim Acta

PubMed ID: 35151402

Doi: 10.1016/j.aca.2022.339551

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Bioinformatics based discovery of new keratinases in protease family M36

Authors: Jingwen Qiu, Kristian Barrett, Casper Wilkens, Anne S Meyer

Journal: N Biotechnol

PubMed ID: 35032710

Doi: 10.1016/j.nbt.2022.01.004

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An Active Peptide-Based Packaging System to Improve the Freshness and Safety of Fish Products: A Case Study

Authors: Rosa Luisa Ambrosio, Marta Gogliettino, Bruna Agrillo, Yolande T R Proroga, Marco Balestrieri, Lorena Gratino, Daniela Cristiano, Gianna Palmieri, Aniello Anastasio

Journal: Foods

PubMed ID: 35159493

Doi: 10.3390/foods11030338

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Anti-aquaporin-4 immunoglobulin G colorimetric detection by silver nanoparticles

Authors: Akemi M Higa, Ariana S Moraes, Flávio M Shimizu, Raquel G Bueno, Luís A Peroni, Francisco T Strixino, Nise A C Sousa, Elenice Deffune, Ana Lívia C Bovolato, Osvaldo N Oliveira, Doralina G Brum, Fabio L Leite

Journal: Nanomedicine

PubMed ID: 35114406

Doi: 10.1016/j.nano.2022.102531

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Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Filamin C, Scy p 9

Authors: Xin-Rong He, Yang Yang, Shuai Kang, Ye-Xin Chen, Pei-Yi Zheng, Gui-Xia Chen, Xiao-Mei Chen, Min-Jie Cao, Tengchuan Jin, Guang-Ming Liu

Journal: J Agric Food Chem

PubMed ID: 35040643

Doi: 10.1021/acs.jafc.1c07922

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Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages

Authors: Fangfang Yu, Wenxia Tian, Jie Dong

Journal: Int Immunopharmacol

PubMed ID: 35045357

Doi: 10.1016/j.intimp.2021.108514

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Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment

Authors: Deepika Narayanan, Danyal Tahseen, Brooke R Bartley, Stephen A Moore, Rebecca Simonette, Peter L Rady, Stephen K Tyring

Journal: Virus Genes

PubMed ID: 35000075

Doi: 10.1007/s11262-021-01880-7

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Preparation of Edible Films with and Lactobionic Acid Produced by Sweet Whey Fermentation

Authors: Sara Sáez-Orviz, Ismael Marcet, Manuel Rendueles, Mario Díaz

Journal: Membranes (Basel)

PubMed ID: 35207037

Doi: 10.3390/membranes12020115

Products & Services: Proteins, Expression, Isolation and Analysis

Genome-wide identification and expression profile of YABBY genes in

Authors: Chengru Li, Na Dong, Liming Shen, Meng Lu, Junwen Zhai, Yamei Zhao, Lei Chen, Zhiting Wan, Zhongjian Liu, Hui Ren, Shasha Wu

Journal: PeerJ

PubMed ID: 35036123

Doi: 10.7717/peerj.12558

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Selection and T-cell antigenicity of synthetic long peptides derived from SARS-CoV-2

Authors: Katarzyna Piadel, Amin Haybatollahi, Angus George Dalgleish, Peter Lawrence Smith

Journal: J Gen Virol

PubMed ID: 35014605

Doi: 10.1099/jgv.0.001698

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Penetration of the SARS-CoV-2 Spike Protein across the Blood-Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing

Authors: Dániel Petrovszki, Fruzsina R Walter, Judit P Vigh, Anna Kocsis, Sándor Valkai, Mária A Deli, András Dér

Journal: Biomedicines

PubMed ID: 35052867

Doi: 10.3390/biomedicines10010188

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Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands

Authors: Ting Zhang, Minya Zhou, Heqing Cai, Kunning Yan, Yiwen Zha, Wenwen Zhuang, Jingyan Liang, Yong Cheng

Journal: Transgenic Res

PubMed ID: 35034272

Doi: 10.1007/s11248-021-00292-5

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Large inter-individual variability of cellular and humoral immunological responses to mRNA-1273 (Moderna) vaccination against SARS-CoV-2 in health care workers

Authors: Alexander Krüttgen, Gerhard Haase, Helga Haefner, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223670

Doi: 10.7774/cevr.2022.11.1.96

ROS-regulated phosphorylation of ITPKB by CAMK2G drives cisplatin resistance in ovarian cancer

Authors: Jie Li, Cuimiao Zheng, Mingshuo Wang, Anna D Umano, Qingyuan Dai, Chunyu Zhang, Hua Huang, Qing Yang, Xianzhi Yang, Jingyi Lu, Wenfeng Pan, Bo Li, Shuzhong Yao, Chaoyun Pan

Journal: Oncogene

PubMed ID: 35039634

Doi: 10.1038/s41388-021-02149-x

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Investigating Constraints Along the Plant Secretory Pathway to Improve Production of a SARS-CoV-2 Spike Vaccine Candidate

Authors: Emmanuel Margolin, Matthew Verbeek, Warren de Moor, Ros Chapman, Ann Meyers, Georgia Schäfer, Anna-Lise Williamson, Edward Rybicki

Journal: Front Plant Sci

PubMed ID: 35058959

Doi: 10.3389/fpls.2021.798822

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Heterogeneous Ribonucleoprotein A1 (hnRNPA1) Interacts with the Nucleoprotein of the Influenza a Virus and Impedes Virus Replication

Authors: Ramandeep Kaur, Jyoti Batra, Olga Stuchlik, Matthew S Reed, Jan Pohl, Suryaprakash Sambhara, Sunil Kumar Lal

Journal: Viruses

PubMed ID: 35215793

Doi: 10.3390/v14020199

Products & Services: Mammalian Expression

Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation

Authors: María Teresa Bueno-Carrasco, Jorge Cuéllar, Marte I Flydal, César Santiago, Trond-André Kråkenes, Rune Kleppe, José R López-Blanco, Miguel Marcilla, Knut Teigen, Sara Alvira, Pablo Chacón, Aurora Martinez, José M Valpuesta

Journal: Nat Commun

PubMed ID: 35013193

Doi: 10.1038/s41467-021-27657-y

Products & Services: Proteins, Expression, Isolation and Analysis

Immune escape mutations selected by neutralizing antibodies in natural HIV-1 infection can alter coreceptor usage repertoire of the transmitted/founder virus

Authors: Manukumar Honnayakanahalli Marichannegowda, Hongshuo Song

Journal: Virology

PubMed ID: 35144109

Doi: 10.1016/j.virol.2022.01.010

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Human α-defensin 6 (HD6) suppresses CRC proliferation and metastasis through abolished EGF/EGFR signaling pathway

Authors: Po-Li Wei, Jang-Chun Lin, Chin-Sheng Hung, Precious Takondwa Makondi, Uyanga Batzorig, Tung-Cheng Chang, Chien-Yu Huang, Yu-Jia Chang

Journal: Int J Med Sci

PubMed ID: 34975297

Doi: 10.7150/ijms.64850

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Analysis of RNA-containing compartments by hybridization and proximity labeling in cultured human cells

Authors: Karen Yap, Tek Hong Chung, Eugene V Makeyev

Journal: STAR Protoc

PubMed ID: 35128480

Doi: 10.1016/j.xpro.2022.101139

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Cardiovascular-specific PSEN1 deletion leads to abnormalities in calcium homeostasis

Authors: Xiao-Wei Song, Feng Zhao, Jing Yang, Qing-Ning Yuan, Zhen-Yu Zeng, Ming Shen, Ying Tang, Mi Cao, Ya-Feng Shen, Song-Hua Li, Yong-Ji Yang, Hong Wu, Xian-Xian Zhao, Shu-Ting Hu

Journal: Cell Biol Int

PubMed ID: 34939719

Doi: 10.1002/cbin.11753

Products & Services: Proteins, Expression, Isolation and Analysis

Schistosome TRPML channels play a role in neuromuscular activity and tegumental integrity

Authors: Swarna Bais, Abigail Norwillo, Gordon Ruthel, De'Broski R Herbert, Bruce D Freedman, Robert M Greenberg

Journal: Biochimie

PubMed ID: 34990770

Doi: 10.1016/j.biochi.2021.12.018

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Genome-Wide Identification and Expression Profiles of Genes in L

Authors: Meng Lu, Xiang-Xiao Meng, Yi-Ming Zhang, Xue-Wen Zhu, Jun Li, Wei-Qiang Chen, Hui-Hua Wan, Si-Fan Wang, Xue Cao, Wei Sun, Yao-Lei Mi, Jun-Wen Zhai

Journal: Cannabis Cannabinoid Res

PubMed ID: 35020417

Doi: 10.1089/can.2021.0153

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A phage parasite deploys a nicking nuclease effector to inhibit viral host replication

Authors: Kristen N LeGault, Zachary K Barth, Peter DePaola, Kimberley D Seed

Journal: Nucleic Acids Res

PubMed ID: 35066583

Doi: 10.1093/nar/gkac002

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A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

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Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

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High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

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theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions

Authors: Teresa Lopes Gomes, Virgínia de Oliveira-Marques, Richard John Hampson, António Jacinto, Luciana Vieira de Moraes, Rui Gonçalo Martinho

Journal: Front Pharmacol

PubMed ID: 35069190

Doi: 10.3389/fphar.2021.752787

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Characterization of male-biased fatty acid desaturase in the jewel wasp Nasonia vitripennis and its role in pheromone production

Authors: Jian-Qiu Cheng, Yu-Mei Tao, Jing Li, Yong-Zhuo Chen, Hao-Yuan Hu

Journal: J Exp Zool B Mol Dev Evol

PubMed ID: 34995007

Doi: 10.1002/jez.b.23120

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Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR

Authors: Zhenyu Wang, Jing Chen, Qiong-Ge Zhang, Kai Huang, Dan Ma, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 35085949

Doi: 10.1016/j.vetmic.2022.109354

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Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay

Authors: Kai Zhang, Zhenqiang Fan, Yue Huang, Yuedi Ding, Minhao Xie, Minghe Wang

Journal: Talanta

PubMed ID: 34998144

Doi: 10.1016/j.talanta.2022.123207

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Self-Assembly of Flagellin into Immunostimulatory Ring-like Nanostructures as an Antigen Delivery System

Authors: Mélanie Côté-Cyr, Ximena Zottig, Laurie Gauthier, Denis Archambault, Steve Bourgault

Journal: ACS Biomater Sci Eng

PubMed ID: 35080372

Doi: 10.1021/acsbiomaterials.1c01332

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SARS-CoV-2 Seroprevalence Among Whole Blood Donors During First Wave of Covid-19 Pandemic in India

Authors: Srinivasa Rao Chunchu, Ushasree Ravula, Vikram Kumar Gente, Srinivas Bacchu, S Pandu Ranga Rao, Srujaleswari Mooli

Journal: Indian J Hematol Blood Transfus

PubMed ID: 35125705

Doi: 10.1007/s12288-021-01512-y

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Heterologous immunization with BNT162b2 followed by mRNA-1273 in dialysis patients: seroconversion and presence of neutralizing antibodies

Authors: Niko Kohmer, Holger F Rabenau, Sandra Ciesek, Bernhard K Krämer, Uwe Göttmann, Christine Keller, Daniela Rose, Carsten Blume, Michael Thomas, Alexander Lammert, Anne Lammert

Journal: Nephrol Dial Transplant

PubMed ID: 35099023

Doi: 10.1093/ndt/gfac018

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Circular RNA circFGFR1 Functions as an Oncogene in Glioblastoma Cells through Sponging to hsa-miR-224-5p

Authors: Qian Zhang, Shan Chen, Yingwei Zhen, Peng Gao, Zhenyu Zhang, Hao Guo, Yong Wang

Journal: J Immunol Res

PubMed ID: 35059468

Doi: 10.1155/2022/7990251

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Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold

Authors: Yaw Bia Tan, Laura Sandra Lello, Xin Liu, Yee-Song Law, Congbao Kang, Julien Lescar, Jie Zheng, Andres Merits, Dahai Luo

Journal: Nucleic Acids Res

PubMed ID: 35037043

Doi: 10.1093/nar/gkab1302

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Porphyromonas gingivalis infection promotes inflammation via inhibition of the AhR signalling pathway in periodontitis

Authors: Ting Hao, Rui Zhang, Tian Zhao, Juan Wu, Wai Keung Leung, Jie Yang, Weibin Sun

Journal: Cell Prolif

PubMed ID: 36446468

Doi: 10.1111/cpr.13364

Products & Services: Proteins, Expression, Isolation and Analysis

Full-length recombinant antibodies from : production, characterization, effector function (Fc) engineering, and clinical evaluation

Authors:

Journal: MAbs

PubMed ID: 36018829

Doi: 10.1080/19420862.2022.2111748

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Circular RNA circRNA_0082835 promotes progression and lymphatic metastasis of primary melanoma by sponging microRNA miRNA-429

Authors: Yute Sun, Zuoqiong Hou, Binlin Luo, Chujun Li, Jinfang Liu, Jianlan Liu, Jian Tang, Gang Yao

Journal: Bioengineered

PubMed ID: 34288815

Doi: 10.1080/21655979.2021.1953822

Products & Services: Proteins, Expression, Isolation and Analysis

Long non-coding RNA SNHG5 regulates ulcerative colitis via microRNA-375 / Janus kinase-2 axis

Authors: Hui Li, Ji Xuan, Wei Zhang, Zhentao An, Xinyu Fan, Min Lu, Yaozhou Tian

Journal: Bioengineered

PubMed ID: 34334085

Doi: 10.1080/21655979.2021.1953219

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a human antibody fragment directed against the alpha folate receptor as a promising molecule for targeted application

Authors: Nattihda Parakasikron, Chatchai Chaotham, Pithi Chanvorachote, Chanida Vinayanuwattikun, Visarut Buranasudja, Pornchanok Taweecheep, Kannika Khantasup

Journal: Drug Deliv

PubMed ID: 34236266

Doi: 10.1080/10717544.2021.1943055

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microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis

Authors: Zixin Hou, Ji Chen, Huan Yang, Xiaoling Hu, Fengrui Yang

Journal: Adipocyte

PubMed ID: 34311651

Doi: 10.1080/21623945.2021.1938829

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Mesenchymal Stem/Stromal Cells Overexpressing CXCR4 Revealed Enhanced Migration: A Lesson Learned from the Pathogenesis of WHIM Syndrome

Authors: Hamid Reza Bidkhori, Ahmad Reza Bahrami, Moein Farshchian, Asieh Heirani-Tabasi, Mahdi Mirahmadi, Halimeh Hasanzadeh, Naghmeh Ahmadiankia, Reza Faridhosseini, Mahtab Dastpak, Arezoo Gowhari Shabgah, Maryam M Matin

Journal: Cell Transplant

PubMed ID: 34807749

Doi: 10.1177/09636897211054498

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Targeted therapy of irritable bowel syndrome with anti-inflammatory cytokines

Authors: Sunil Kumar, Priyanka Singh, Awanish Kumar

Journal: Clin J Gastroenterol

PubMed ID: 34862947

Doi: 10.1007/s12328-021-01555-8

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Long non-coding RNA H19 protects against intracerebral hemorrhage injuries via regulating microRNA-106b-5p/acyl-CoA synthetase long chain family member 4 axis

Authors: Bing Chen, Haoran Wang, Chenglin Lv, Chongdan Mao, Yuguang Cui

Journal: Bioengineered

PubMed ID: 34288826

Doi: 10.1080/21655979.2021.1951070

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Rapid test to assess the escape of SARS-CoV-2 variants of concern

Authors: Jacob T Heggestad, Rhett J Britton, David S Kinnamon, Simone A Wall, Daniel Y Joh, Angus M Hucknall, Lyra B Olson, Jack G Anderson, Anna Mazur, Cameron R Wolfe, Thomas H Oguin, Bruce A Sullenger, Thomas W Burke, Bryan D Kraft, Gregory D Sempowski, Christopher W Woods, Ashutosh Chilkoti

Journal: Sci Adv

PubMed ID: 34860546

Doi: 10.1126/sciadv.abl7682

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Synthesis and anti-inflammatory activities of glycyrrhetinic acid derivatives containing disulfide bond

Authors: Qiuping Zhang, Yanni Wang, Zongyuan Wang, Eyad Abdulwhab Hamoud Mohammed, Quanyi Zhao, Dian He, Zhen Wang

Journal: Bioorg Chem

PubMed ID: 34902645

Doi: 10.1016/j.bioorg.2021.105542

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sp nov, a novel phenylacetic acid degrading bacterium isolated from sludge

Authors: Fa-Hu Pang, Hui-Ying Yang, Jie Sun, Xing Yu, Hao Zhang

Journal: Int J Syst Evol Microbiol

PubMed ID: 34878373

Doi: 10.1099/ijsem.0.005144

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KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth

Authors: Michiko Shimoda, Yuanzhi Lyu, Kang-Hsin Wang, Ashish Kumar, Hiroki Miura, Joshua F Meckler, Ryan R Davis, Chanikarn Chantarasrivong, Chie Izumiya, Clifford G Tepper, Ken-Ichi Nakajima, Joseph Tuscano, Gustavo Barisone, Yoshihiro Izumiya

Journal: Commun Biol

PubMed ID: 34857874

Doi: 10.1038/s42003-021-02853-0

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A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes

Authors: Jing-Jing Xu, Xiao-Fan Zhang, Yan Jiang, Hang Fan, Jian-Xu Li, Chen-Yi Li, Qing Zhao, Lei Yang, Yong-Hong Hu, Cathie Martin, Xiao-Ya Chen

Journal: Sci Adv

PubMed ID: 34878842

Doi: 10.1126/sciadv.abl3594

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Population genetics of cycas necrotic stunt virus and the development of multiplex RT-PCR diagnostics

Authors: Cullen M Shaffer, David C Michener, Nastassia B Vlasava, Henry Chotkowski, Ioannis E Tzanetakis

Journal: Virus Res

PubMed ID: 34906655

Doi: 10.1016/j.virusres.2021.198655

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Novel reverse genetics of genotype I and III Japanese encephalitis viruses assembled through transformation associated recombination in yeast: The reporter viruses expressing a green fluorescent protein for the antiviral screening assay

Authors: Chenxi Li, Xuan Chen, Yanyang Zhou, Jingbo Hu, Xinjie Wang, Yanhua Li

Journal: Antiviral Res

PubMed ID: 34973281

Doi: 10.1016/j.antiviral.2021.105233

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ACE2-IgG1 fusions with improved and activity against SARS-CoV-2

Authors: Naoki Iwanaga, Laura Cooper, Lijun Rong, Nicholas J Maness, Brandon Beddingfield, Zhongnan Qin, Jackelyn Crabtree, Ralph A Tripp, Haoran Yang, Robert Blair, Sonia Jangra, Adolfo García-Sastre, Michael Schotsaert, Chandra Sruti, James E Robinson, Akhilesh Srivastava, Felix Rabito, Xuebin Qin, Jay K Kolls

Journal: iScience

PubMed ID: 34957381

Doi: 10.1016/j.isci.2021.103670

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Down-regulation of miR-340-5p promoted osteogenic differentiation through regulation of runt-related transcription factor-2 (RUNX2) in MC3T3-E1 cells

Authors: Xiaochen Wang, Yaochuan Mi, Wei He, Xiaona Hu, Shuo Yang, Lu Zhao, Yanyang Zhang, Binhong Wen

Journal: Bioengineered

PubMed ID: 33818278

Doi: 10.1080/21655979.2021.1905259

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Implications of Quenching-to-Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye-Labeled Nanoparticles

Authors: Guangze Yang+ , Yun Liu+ , Yue Hui, Tengjisi, Dong Chen, David A. Weitz, and Chun-Xia Zhao

Journal: ANGEWANDTE CHEMIE

Doi: doi.org/10.1002/anie.202101730

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Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin

Authors: Yan Wang, Zhiqiang Cheng, Jing Xu, Meina Lai, Liming Liu, Min Zuo, Lin Dang

Journal: Bioengineered

PubMed ID: 34076564

Doi: 10.1080/21655979.2021.1924544

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The arthrospore-related gene Acaxl2 is involved in cephalosporin C production in industrial Acremonium chrysogenum by the regulatory factors AcFKH1 and CPCR1

Authors: Yan Xu, Ling Liu, Zhen Chen, Xiwei Tian, Ju Chu

Journal: J Biotechnol

PubMed ID: 34954288

Doi: 10.1016/j.jbiotec.2021.12.011

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