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Immune escape mutations selected by neutralizing antibodies in natural HIV-1 infection can alter coreceptor usage repertoire of the transmitted/founder virus

Authors: Manukumar Honnayakanahalli Marichannegowda, Hongshuo Song

Journal: Virology

PubMed ID: 35144109

Doi: 10.1016/j.virol.2022.01.010

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EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells

Authors: Ying Li, Jiuxiang Feng, Yue Bian, Wei Cheng, Chong Qiao

Journal: Folia Histochem Cytobiol

PubMed ID: 35038162

Doi: 10.5603/FHC.a2022.0001

Products & Services: Plasmid DNA Preparation

Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging

Authors: Manning Y Huang, Meenakshi B Joshi, Michael J Boucher, Sujin Lee, Liza C Loza, Elizabeth A Gaylord, Tamara L Doering, Hiten D Madhani

Journal: Genetics

PubMed ID: 34791226

Doi: 10.1093/genetics/iyab180

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Cardiovascular-specific PSEN1 deletion leads to abnormalities in calcium homeostasis

Authors: Xiao-Wei Song, Feng Zhao, Jing Yang, Qing-Ning Yuan, Zhen-Yu Zeng, Ming Shen, Ying Tang, Mi Cao, Ya-Feng Shen, Song-Hua Li, Yong-Ji Yang, Hong Wu, Xian-Xian Zhao, Shu-Ting Hu

Journal: Cell Biol Int

PubMed ID: 34939719

Doi: 10.1002/cbin.11753

Products & Services: Proteins, Expression, Isolation and Analysis

Lipoxin A and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway

Authors: Fen Xu, Jiamin Zhang, Xiaoyan Zhou, Hua Hao

Journal: Exp Cell Res

PubMed ID: 35026282

Doi: 10.1016/j.yexcr.2022.113025

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Molecular Characterization of Mg-Chelatase CHLI Subunit in Pea ( L)

Authors: Cai-Jun Wu, Jie Wang, Jun Zhu, Jing Ren, You-Xin Yang, Tao Luo, Lu-Xi Xu, Qing-Hong Zhou, Xu-Feng Xiao, Yu-Xin Zhou, Sha Luo

Journal: Front Plant Sci

PubMed ID: 35145539

Doi: 10.3389/fpls.2022.821683

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Genome-Wide Identification and Expression Profiles of Genes in L

Authors: Meng Lu, Xiang-Xiao Meng, Yi-Ming Zhang, Xue-Wen Zhu, Jun Li, Wei-Qiang Chen, Hui-Hua Wan, Si-Fan Wang, Xue Cao, Wei Sun, Yao-Lei Mi, Jun-Wen Zhai

Journal: Cannabis Cannabinoid Res

PubMed ID: 35020417

Doi: 10.1089/can.2021.0153

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Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

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Bioinformatics based discovery of new keratinases in protease family M36

Authors: Jingwen Qiu, Kristian Barrett, Casper Wilkens, Anne S Meyer

Journal: N Biotechnol

PubMed ID: 35032710

Doi: 10.1016/j.nbt.2022.01.004

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An Active Peptide-Based Packaging System to Improve the Freshness and Safety of Fish Products: A Case Study

Authors: Rosa Luisa Ambrosio, Marta Gogliettino, Bruna Agrillo, Yolande T R Proroga, Marco Balestrieri, Lorena Gratino, Daniela Cristiano, Gianna Palmieri, Aniello Anastasio

Journal: Foods

PubMed ID: 35159493

Doi: 10.3390/foods11030338

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Anti-aquaporin-4 immunoglobulin G colorimetric detection by silver nanoparticles

Authors: Akemi M Higa, Ariana S Moraes, Flávio M Shimizu, Raquel G Bueno, Luís A Peroni, Francisco T Strixino, Nise A C Sousa, Elenice Deffune, Ana Lívia C Bovolato, Osvaldo N Oliveira, Doralina G Brum, Fabio L Leite

Journal: Nanomedicine

PubMed ID: 35114406

Doi: 10.1016/j.nano.2022.102531

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Solid-Phase Extraction Approaches for Improving Oligosaccharide and Small Peptide Identification with Liquid Chromatography-High-Resolution Mass Spectrometry: A Case Study on Proteolyzed Almond Extract

Authors: Yu-Ping Huang, Randall C Robinson, Fernanda Furlan Goncalves Dias, Juliana Maria Leite Nobrega de Moura Bell, Daniela Barile

Journal: Foods

PubMed ID: 35159490

Doi: 10.3390/foods11030340

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Protection and Alleviated Inflammation Induced by Virus-like Particle Vaccines Containing MSP-8, MSP-9 and RAP1

Authors: Su-Hwa Lee, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 35214662

Doi: 10.3390/vaccines10020203

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Protection and Alleviated Inflammation Induced by Virus-like Particle Vaccines Containing MSP-8, MSP-9 and RAP1

Authors: Su-Hwa Lee, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 35214662

Doi: 10.3390/vaccines10020203

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Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations

Authors: Anju Jaiswal, D Dash, Rashmi Singh

Journal: Toxicol Appl Pharmacol

PubMed ID: 34998855

Doi: 10.1016/j.taap.2021.115861

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Heterologous Expression and Functional Characterization of CAP18 from

Authors: Mahla Nikpoor, Azadeh Lohrasbi-Nejad, Jafar Zolala

Journal: Rep Biochem Mol Biol

PubMed ID: 35291606

Doi: 10.52547/rbmb.10.4.622

Products & Services: Proteins, Expression, Isolation and Analysis

ROS-regulated phosphorylation of ITPKB by CAMK2G drives cisplatin resistance in ovarian cancer

Authors: Jie Li, Cuimiao Zheng, Mingshuo Wang, Anna D Umano, Qingyuan Dai, Chunyu Zhang, Hua Huang, Qing Yang, Xianzhi Yang, Jingyi Lu, Wenfeng Pan, Bo Li, Shuzhong Yao, Chaoyun Pan

Journal: Oncogene

PubMed ID: 35039634

Doi: 10.1038/s41388-021-02149-x

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Multifunctional liposomal nanostructure-mediated siRNA/bortezomib co-delivery for SHARP1 knockdown in MLL-AF6 acute myeloid leukemia

Authors: Sameh A Mohammed, Yang Ju

Journal: Biomater Adv

PubMed ID: 35577689

Doi: 10.1016/j.msec.2022.112663

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Human α-defensin 6 (HD6) suppresses CRC proliferation and metastasis through abolished EGF/EGFR signaling pathway

Authors: Po-Li Wei, Jang-Chun Lin, Chin-Sheng Hung, Precious Takondwa Makondi, Uyanga Batzorig, Tung-Cheng Chang, Chien-Yu Huang, Yu-Jia Chang

Journal: Int J Med Sci

PubMed ID: 34975297

Doi: 10.7150/ijms.64850

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Control of subunit stoichiometry in single-chain MspA nanopores

Authors: Mikhail Pavlenok, Luning Yu, Dominik Herrmann, Meni Wanunu, Michael Niederweis

Journal: Biophys J

PubMed ID: 35101416

Doi: 10.1016/j.bpj.2022.01.022

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Activity-based protein profiling reveals dynamic substrate-specific cellulase secretion by saprotrophic basidiomycetes

Authors: Nicholas G S McGregor, Casper de Boer, Mikhaaeel Santos, Mireille Haon, David Navarro, Sybrin Schroder, Jean-Guy Berrin, Herman S Overkleeft, Gideon J Davies

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 35418096

Doi: 10.1186/s13068-022-02107-z

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Schistosome TRPML channels play a role in neuromuscular activity and tegumental integrity

Authors: Swarna Bais, Abigail Norwillo, Gordon Ruthel, De'Broski R Herbert, Bruce D Freedman, Robert M Greenberg

Journal: Biochimie

PubMed ID: 34990770

Doi: 10.1016/j.biochi.2021.12.018

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Analysis of RNA-containing compartments by hybridization and proximity labeling in cultured human cells

Authors: Karen Yap, Tek Hong Chung, Eugene V Makeyev

Journal: STAR Protoc

PubMed ID: 35128480

Doi: 10.1016/j.xpro.2022.101139

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The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential

Authors: Lu Wang, Xi Wang, Xiying Lv, Qiushuo Jin, Hongcai Shang, Chih-Chen Wang, Lei Wang

Journal: Redox Biol

PubMed ID: 35077997

Doi: 10.1016/j.redox.2022.102244

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A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

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High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

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A phage parasite deploys a nicking nuclease effector to inhibit viral host replication

Authors: Kristen N LeGault, Zachary K Barth, Peter DePaola, Kimberley D Seed

Journal: Nucleic Acids Res

PubMed ID: 35066583

Doi: 10.1093/nar/gkac002

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Inhibiting L1CAM Reverses Cisplatin Resistance of Triple Negative Breast Cancer Cells by Blocking AKT Signaling Pathway

Authors: Lu-Yao Zhang, Zhi-Xin Shen, Lu Guo

Journal: Cancer Invest

PubMed ID: 35040385

Doi: 10.1080/07357907.2021.2016801

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theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions

Authors: Teresa Lopes Gomes, Virgínia de Oliveira-Marques, Richard John Hampson, António Jacinto, Luciana Vieira de Moraes, Rui Gonçalo Martinho

Journal: Front Pharmacol

PubMed ID: 35069190

Doi: 10.3389/fphar.2021.752787

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Characterization of male-biased fatty acid desaturase in the jewel wasp Nasonia vitripennis and its role in pheromone production

Authors: Jian-Qiu Cheng, Yu-Mei Tao, Jing Li, Yong-Zhuo Chen, Hao-Yuan Hu

Journal: J Exp Zool B Mol Dev Evol

PubMed ID: 34995007

Doi: 10.1002/jez.b.23120

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Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR

Authors: Zhenyu Wang, Jing Chen, Qiong-Ge Zhang, Kai Huang, Dan Ma, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 35085949

Doi: 10.1016/j.vetmic.2022.109354

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Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay

Authors: Kai Zhang, Zhenqiang Fan, Yue Huang, Yuedi Ding, Minhao Xie, Minghe Wang

Journal: Talanta

PubMed ID: 34998144

Doi: 10.1016/j.talanta.2022.123207

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Self-Assembly of Flagellin into Immunostimulatory Ring-like Nanostructures as an Antigen Delivery System

Authors: Mélanie Côté-Cyr, Ximena Zottig, Laurie Gauthier, Denis Archambault, Steve Bourgault

Journal: ACS Biomater Sci Eng

PubMed ID: 35080372

Doi: 10.1021/acsbiomaterials.1c01332

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SARS-CoV-2 Seroprevalence Among Whole Blood Donors During First Wave of Covid-19 Pandemic in India

Authors: Srinivasa Rao Chunchu, Ushasree Ravula, Vikram Kumar Gente, Srinivas Bacchu, S Pandu Ranga Rao, Srujaleswari Mooli

Journal: Indian J Hematol Blood Transfus

PubMed ID: 35125705

Doi: 10.1007/s12288-021-01512-y

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Heterologous immunization with BNT162b2 followed by mRNA-1273 in dialysis patients: seroconversion and presence of neutralizing antibodies

Authors: Niko Kohmer, Holger F Rabenau, Sandra Ciesek, Bernhard K Krämer, Uwe Göttmann, Christine Keller, Daniela Rose, Carsten Blume, Michael Thomas, Alexander Lammert, Anne Lammert

Journal: Nephrol Dial Transplant

PubMed ID: 35099023

Doi: 10.1093/ndt/gfac018

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Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response

Authors: Satoshi Shimizu, Yoichi Sunagawa, Naruto Hajika, Natsumi Yorimitsu, Yasufumi Katanasaka, Masafumi Funamoto, Yusuke Miyazaki, Nurmila Sari, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto

Journal: Int J Biol Sci

PubMed ID: 35173540

Doi: 10.7150/ijbs.65664

Products & Services: Proteins, Expression, Isolation and Analysis

Circular RNA circFGFR1 Functions as an Oncogene in Glioblastoma Cells through Sponging to hsa-miR-224-5p

Authors: Qian Zhang, Shan Chen, Yingwei Zhen, Peng Gao, Zhenyu Zhang, Hao Guo, Yong Wang

Journal: J Immunol Res

PubMed ID: 35059468

Doi: 10.1155/2022/7990251

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Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold

Authors: Yaw Bia Tan, Laura Sandra Lello, Xin Liu, Yee-Song Law, Congbao Kang, Julien Lescar, Jie Zheng, Andres Merits, Dahai Luo

Journal: Nucleic Acids Res

PubMed ID: 35037043

Doi: 10.1093/nar/gkab1302

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A combination of multiple autoantibodies is associated with the risk of Alzheimer's disease and cognitive impairment

Authors: Sung-Mi Shim, Young Ho Koh, Jong-Hoon Kim, Jae-Pil Jeon

Journal: Sci Rep

PubMed ID: 35079008

Doi: 10.1038/s41598-021-04556-2

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Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models

Authors: Aviral Kumar, Amarnath Singam, Guruprasadh Swaminathan, Naresh Killi, Naveen Kumar Tangudu, Jedy Jose, Rathna Gundloori Vn, Lekha Dinesh Kumar

Journal: Nanoscale

PubMed ID: 34913453

Doi: 10.1039/d1nr04411g

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Improved myocardial performance in infarcted rat heart by injection of disulfide-cross-linked chitosan hydrogels loaded with basic fibroblast growth factor

Authors: Bo Fu, Xiaobei Wang, Zhengda Chen, Nan Jiang, Zhigang Guo, Yuhui Zhang, Shaopeng Zhang, Xiankun Liu, Li Liu

Journal: J Mater Chem B

PubMed ID: 35014648

Doi: 10.1039/d1tb01961a

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GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus

Authors: Nitaya Indrawattana, Pisinee Aiumurai, Nawannaporn Sae-Lim, Watee Seesuay, Onrapak Reamtong, Manas Chongsa-Nguan, Wanpen Chaicumpa, Nitat Sookrung

Journal: Diagnostics (Basel)

PubMed ID: 35054302

Doi: 10.3390/diagnostics12010136

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Molecular Characterization of Mg-Chelatase CHLI Subunit in Pea ( L)

Authors: Cai-Jun Wu, Jie Wang, Jun Zhu, Jing Ren, You-Xin Yang, Tao Luo, Lu-Xi Xu, Qing-Hong Zhou, Xu-Feng Xiao, Yu-Xin Zhou, Sha Luo

Journal: Front Plant Sci

PubMed ID: 35145539

Doi: 10.3389/fpls.2022.821683

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Core-shell "loading-type" nanomaterials towards: Simultaneous imaging analysis of glutathione and microRNA

Authors: Lin-Lin Lu, Qin Zhang, Yu Gu, Xiang-Ling Li, Jing Jing Xie

Journal: Anal Chim Acta

PubMed ID: 35151402

Doi: 10.1016/j.aca.2022.339551

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Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test

Authors: Qiao Wang, Lili Feng, Haohai Zhang, Juehua Gao, Changchuin Mao, Esther Landesman-Bollag, Gustavo Mostoslavsky, Justin M Lunderberg, Weina Zheng, Shushun Hao, Wenda Gao

Journal: Antib Ther

PubMed ID: 35146332

Doi: 10.1093/abt/tbac004

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Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Filamin C, Scy p 9

Authors: Xin-Rong He, Yang Yang, Shuai Kang, Ye-Xin Chen, Pei-Yi Zheng, Gui-Xia Chen, Xiao-Mei Chen, Min-Jie Cao, Tengchuan Jin, Guang-Ming Liu

Journal: J Agric Food Chem

PubMed ID: 35040643

Doi: 10.1021/acs.jafc.1c07922

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Severity of adverse reactions is associated with T-cell response in mRNA-1273 vaccinated health care workers

Authors: Hanna Klingel, Maike Lauen, Alexander Krüttgen, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223673

Doi: 10.7774/cevr.2022.11.1.121

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Preparation of Edible Films with and Lactobionic Acid Produced by Sweet Whey Fermentation

Authors: Sara Sáez-Orviz, Ismael Marcet, Manuel Rendueles, Mario Díaz

Journal: Membranes (Basel)

PubMed ID: 35207037

Doi: 10.3390/membranes12020115

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Selection and T-cell antigenicity of synthetic long peptides derived from SARS-CoV-2

Authors: Katarzyna Piadel, Amin Haybatollahi, Angus George Dalgleish, Peter Lawrence Smith

Journal: J Gen Virol

PubMed ID: 35014605

Doi: 10.1099/jgv.0.001698

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Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment

Authors: Deepika Narayanan, Danyal Tahseen, Brooke R Bartley, Stephen A Moore, Rebecca Simonette, Peter L Rady, Stephen K Tyring

Journal: Virus Genes

PubMed ID: 35000075

Doi: 10.1007/s11262-021-01880-7

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Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages

Authors: Fangfang Yu, Wenxia Tian, Jie Dong

Journal: Int Immunopharmacol

PubMed ID: 35045357

Doi: 10.1016/j.intimp.2021.108514

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Genome-wide identification and expression profile of YABBY genes in

Authors: Chengru Li, Na Dong, Liming Shen, Meng Lu, Junwen Zhai, Yamei Zhao, Lei Chen, Zhiting Wan, Zhongjian Liu, Hui Ren, Shasha Wu

Journal: PeerJ

PubMed ID: 35036123

Doi: 10.7717/peerj.12558

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Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3

Authors: Chad S Hewitt, Chittaranjan Das, Daniel P Flaherty

Journal: Biomolecules

PubMed ID: 35053210

Doi: 10.3390/biom12010062

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Penetration of the SARS-CoV-2 Spike Protein across the Blood-Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing

Authors: Dániel Petrovszki, Fruzsina R Walter, Judit P Vigh, Anna Kocsis, Sándor Valkai, Mária A Deli, András Dér

Journal: Biomedicines

PubMed ID: 35052867

Doi: 10.3390/biomedicines10010188

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Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands

Authors: Ting Zhang, Minya Zhou, Heqing Cai, Kunning Yan, Yiwen Zha, Wenwen Zhuang, Jingyan Liang, Yong Cheng

Journal: Transgenic Res

PubMed ID: 35034272

Doi: 10.1007/s11248-021-00292-5

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Large inter-individual variability of cellular and humoral immunological responses to mRNA-1273 (Moderna) vaccination against SARS-CoV-2 in health care workers

Authors: Alexander Krüttgen, Gerhard Haase, Helga Haefner, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223670

Doi: 10.7774/cevr.2022.11.1.96

Full-length recombinant antibodies from : production, characterization, effector function (Fc) engineering, and clinical evaluation

Authors:

Journal: MAbs

PubMed ID: 36018829

Doi: 10.1080/19420862.2022.2111748

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Porphyromonas gingivalis infection promotes inflammation via inhibition of the AhR signalling pathway in periodontitis

Authors: Ting Hao, Rui Zhang, Tian Zhao, Juan Wu, Wai Keung Leung, Jie Yang, Weibin Sun

Journal: Cell Prolif

PubMed ID: 36446468

Doi: 10.1111/cpr.13364

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Circular RNA circRNA_0082835 promotes progression and lymphatic metastasis of primary melanoma by sponging microRNA miRNA-429

Authors: Yute Sun, Zuoqiong Hou, Binlin Luo, Chujun Li, Jinfang Liu, Jianlan Liu, Jian Tang, Gang Yao

Journal: Bioengineered

PubMed ID: 34288815

Doi: 10.1080/21655979.2021.1953822

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Long non-coding RNA SNHG5 regulates ulcerative colitis via microRNA-375 / Janus kinase-2 axis

Authors: Hui Li, Ji Xuan, Wei Zhang, Zhentao An, Xinyu Fan, Min Lu, Yaozhou Tian

Journal: Bioengineered

PubMed ID: 34334085

Doi: 10.1080/21655979.2021.1953219

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Development of a human antibody fragment directed against the alpha folate receptor as a promising molecule for targeted application

Authors: Nattihda Parakasikron, Chatchai Chaotham, Pithi Chanvorachote, Chanida Vinayanuwattikun, Visarut Buranasudja, Pornchanok Taweecheep, Kannika Khantasup

Journal: Drug Deliv

PubMed ID: 34236266

Doi: 10.1080/10717544.2021.1943055

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microRNA-26a shuttled by extracellular vesicles secreted from adipose-derived mesenchymal stem cells reduce neuronal damage through KLF9-mediated regulation of TRAF2/KLF2 axis

Authors: Zixin Hou, Ji Chen, Huan Yang, Xiaoling Hu, Fengrui Yang

Journal: Adipocyte

PubMed ID: 34311651

Doi: 10.1080/21623945.2021.1938829

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Mesenchymal Stem/Stromal Cells Overexpressing CXCR4 Revealed Enhanced Migration: A Lesson Learned from the Pathogenesis of WHIM Syndrome

Authors: Hamid Reza Bidkhori, Ahmad Reza Bahrami, Moein Farshchian, Asieh Heirani-Tabasi, Mahdi Mirahmadi, Halimeh Hasanzadeh, Naghmeh Ahmadiankia, Reza Faridhosseini, Mahtab Dastpak, Arezoo Gowhari Shabgah, Maryam M Matin

Journal: Cell Transplant

PubMed ID: 34807749

Doi: 10.1177/09636897211054498

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Targeted therapy of irritable bowel syndrome with anti-inflammatory cytokines

Authors: Sunil Kumar, Priyanka Singh, Awanish Kumar

Journal: Clin J Gastroenterol

PubMed ID: 34862947

Doi: 10.1007/s12328-021-01555-8

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Long non-coding RNA H19 protects against intracerebral hemorrhage injuries via regulating microRNA-106b-5p/acyl-CoA synthetase long chain family member 4 axis

Authors: Bing Chen, Haoran Wang, Chenglin Lv, Chongdan Mao, Yuguang Cui

Journal: Bioengineered

PubMed ID: 34288826

Doi: 10.1080/21655979.2021.1951070

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Rapid test to assess the escape of SARS-CoV-2 variants of concern

Authors: Jacob T Heggestad, Rhett J Britton, David S Kinnamon, Simone A Wall, Daniel Y Joh, Angus M Hucknall, Lyra B Olson, Jack G Anderson, Anna Mazur, Cameron R Wolfe, Thomas H Oguin, Bruce A Sullenger, Thomas W Burke, Bryan D Kraft, Gregory D Sempowski, Christopher W Woods, Ashutosh Chilkoti

Journal: Sci Adv

PubMed ID: 34860546

Doi: 10.1126/sciadv.abl7682

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Synthesis and anti-inflammatory activities of glycyrrhetinic acid derivatives containing disulfide bond

Authors: Qiuping Zhang, Yanni Wang, Zongyuan Wang, Eyad Abdulwhab Hamoud Mohammed, Quanyi Zhao, Dian He, Zhen Wang

Journal: Bioorg Chem

PubMed ID: 34902645

Doi: 10.1016/j.bioorg.2021.105542

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sp nov, a novel phenylacetic acid degrading bacterium isolated from sludge

Authors: Fa-Hu Pang, Hui-Ying Yang, Jie Sun, Xing Yu, Hao Zhang

Journal: Int J Syst Evol Microbiol

PubMed ID: 34878373

Doi: 10.1099/ijsem.0.005144

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KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth

Authors: Michiko Shimoda, Yuanzhi Lyu, Kang-Hsin Wang, Ashish Kumar, Hiroki Miura, Joshua F Meckler, Ryan R Davis, Chanikarn Chantarasrivong, Chie Izumiya, Clifford G Tepper, Ken-Ichi Nakajima, Joseph Tuscano, Gustavo Barisone, Yoshihiro Izumiya

Journal: Commun Biol

PubMed ID: 34857874

Doi: 10.1038/s42003-021-02853-0

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A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes

Authors: Jing-Jing Xu, Xiao-Fan Zhang, Yan Jiang, Hang Fan, Jian-Xu Li, Chen-Yi Li, Qing Zhao, Lei Yang, Yong-Hong Hu, Cathie Martin, Xiao-Ya Chen

Journal: Sci Adv

PubMed ID: 34878842

Doi: 10.1126/sciadv.abl3594

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Population genetics of cycas necrotic stunt virus and the development of multiplex RT-PCR diagnostics

Authors: Cullen M Shaffer, David C Michener, Nastassia B Vlasava, Henry Chotkowski, Ioannis E Tzanetakis

Journal: Virus Res

PubMed ID: 34906655

Doi: 10.1016/j.virusres.2021.198655

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Novel reverse genetics of genotype I and III Japanese encephalitis viruses assembled through transformation associated recombination in yeast: The reporter viruses expressing a green fluorescent protein for the antiviral screening assay

Authors: Chenxi Li, Xuan Chen, Yanyang Zhou, Jingbo Hu, Xinjie Wang, Yanhua Li

Journal: Antiviral Res

PubMed ID: 34973281

Doi: 10.1016/j.antiviral.2021.105233

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ACE2-IgG1 fusions with improved and activity against SARS-CoV-2

Authors: Naoki Iwanaga, Laura Cooper, Lijun Rong, Nicholas J Maness, Brandon Beddingfield, Zhongnan Qin, Jackelyn Crabtree, Ralph A Tripp, Haoran Yang, Robert Blair, Sonia Jangra, Adolfo García-Sastre, Michael Schotsaert, Chandra Sruti, James E Robinson, Akhilesh Srivastava, Felix Rabito, Xuebin Qin, Jay K Kolls

Journal: iScience

PubMed ID: 34957381

Doi: 10.1016/j.isci.2021.103670

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Down-regulation of miR-340-5p promoted osteogenic differentiation through regulation of runt-related transcription factor-2 (RUNX2) in MC3T3-E1 cells

Authors: Xiaochen Wang, Yaochuan Mi, Wei He, Xiaona Hu, Shuo Yang, Lu Zhao, Yanyang Zhang, Binhong Wen

Journal: Bioengineered

PubMed ID: 33818278

Doi: 10.1080/21655979.2021.1905259

Products & Services: Recombinant Proteins

Implications of Quenching-to-Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye-Labeled Nanoparticles

Authors: Guangze Yang+ , Yun Liu+ , Yue Hui, Tengjisi, Dong Chen, David A. Weitz, and Chun-Xia Zhao

Journal: ANGEWANDTE CHEMIE

Doi: doi.org/10.1002/anie.202101730

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Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin

Authors: Yan Wang, Zhiqiang Cheng, Jing Xu, Meina Lai, Liming Liu, Min Zuo, Lin Dang

Journal: Bioengineered

PubMed ID: 34076564

Doi: 10.1080/21655979.2021.1924544

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The arthrospore-related gene Acaxl2 is involved in cephalosporin C production in industrial Acremonium chrysogenum by the regulatory factors AcFKH1 and CPCR1

Authors: Yan Xu, Ling Liu, Zhen Chen, Xiwei Tian, Ju Chu

Journal: J Biotechnol

PubMed ID: 34954288

Doi: 10.1016/j.jbiotec.2021.12.011

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Physicochemical and molecular transformation of novel functional peptides from Baijiu

Authors: Wei Jia, An Du, Xiaojun Dong, Zibian Fan, Duimin Zhang, Ruihong Wang, Lin Shi

Journal: Food Chem

PubMed ID: 34954580

Doi: 10.1016/j.foodchem.2021.131894

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WHO international standard for SARS-CoV-2 antibodies to determine markers of protection

Authors: Feng Zhu, Thomas Althaus, Chee Wah Tan, Alizée Costantini, Wan Ni Chia, Nguyen Van Vinh Chau, Le Van Tan, Giada Mattiuzzo, Nicola J Rose, Eric Voiglio, Lin-Fa Wang

Journal: Lancet Microbe

PubMed ID: 34901897

Doi: 10.1016/S2666-5247(21)00307-4

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Plasmonically Enhanced Ultrasensitive Epitope-Specific Serologic Assay for COVID-19

Authors: Zheyu Wang, Jeremiah J Morrissey, Lin Liu, Yixuan Wang, Qingjun Zhou, Rajesh R Naik, Srikanth Singamaneni

Journal: Anal Chem

PubMed ID: 34935364

Doi: 10.1021/acs.analchem.1c03676

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Novel nanostructure-coupled biosensor platform for one-step high-throughput quantification of serum neutralizing antibody after COVID-19 vaccination

Authors: Liping Huang, Ying Li, Changyou Luo, Youqian Chen, Nadia Touil, Hicham-El Annaz, Shaoqi Zeng, Tang Dang, Jiawei Liang, Wenjun Hu, Hao Xu, Jiasheng Tu, Lin Wang, Yan Shen, Gang L Liu

Journal: Biosens Bioelectron

PubMed ID: 34920226

Doi: 10.1016/j.bios.2021.113868

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A Stabilized, Monomeric, Receptor Binding Domain Elicits High-Titer Neutralizing Antibodies Against All SARS-CoV-2 Variants of Concern

Authors: Shahbaz Ahmed, Mohammad Suhail Khan, Savitha Gayathri, Randhir Singh, Sahil Kumar, Unnatiben Rajeshbhai Patel, Sameer Kumar Malladi, Raju S Rajmani, Petrus Jansen van Vuren, Shane Riddell, Sarah Goldie, Nidhi Girish, Poorvi Reddy, Aditya Upadhyaya, Suman Pandey, Samreen Siddiqui, Akansha Tyagi, Sujeet Jha, Rajesh Pandey, Oyahida Khatun, Rohan Narayan, Shashank Tripathi, Alexander J McAuley, Nagendrakumar Balasubramanian Singanallur, Seshadri S Vasan, Rajesh P Ringe, Raghavan Varadarajan

Journal: Front Immunol

PubMed ID: 34956193

Doi: 10.3389/fimmu.2021.765211

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Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress

Authors: Celia Salazar, Miriam Barros, Alvaro A Elorza, Lina María Ruiz

Journal: Int J Mol Sci

PubMed ID: 35008815

Doi: 10.3390/ijms23010389

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Glycoside Hydrolase family 30 harbors fungal subfamilies with distinct polysaccharide specificities

Authors: Xinxin Li, Dimitrios Kouzounis, Mirjam A Kabel, Ronald P de Vries, Adiphol Dilokpimol

Journal: N Biotechnol

PubMed ID: 34952234

Doi: 10.1016/j.nbt.2021.12.004

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Cloning, Expression and Inhibitory Effects on Lewis Lung Carcinoma Cells of rAj-Tspin from Sea Cucumber ()

Authors: Rong Qiao, Rong Xiao, Zhong Chen, Jingwei Jiang, Chenghua Yuan, Shuxiang Ning, Jihong Wang, Zunchun Zhou

Journal: Molecules

PubMed ID: 35011462

Doi: 10.3390/molecules27010229

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Progressing Ultragreen, Energy-Efficient Biobased Depolymerization of Poly(ethylene terephthalate) via Microwave-Assisted Green Deep Eutectic Solvent and Enzymatic Treatment

Authors: Olivia A Attallah, Muhammad Azeem, Efstratios Nikolaivits, Evangelos Topakas, Margaret Brennan Fournet

Journal: Polymers (Basel)

PubMed ID: 35012131

Doi: 10.3390/polym14010109

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A de novo ACTB gene pathogenic variant in identical twins with phenotypic variation for hydrops and jejunal atresia

Authors: Kristina Sibbin, Patrick Yap, Denis Nyaga, Raoul Heller, Stephen Evans, Kate Strachan, Salam Alburaiky, Han M Alex Nguyen, Sylvie Hermann-Le Denmat, Austen R D Ganley, Justin M O'Sullivan, Frank H Bloomfield

Journal: Am J Med Genet A

PubMed ID: 34970864

Doi: 10.1002/ajmg.a.62631

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Humoral and cellular immune responses to the SARS-CoV-2 BNT162b2 vaccine among a cohort of solid organ transplant recipients and healthy controls

Authors: Ahmad Yanis, Zaid Haddadin, Andrew J Spieker, Danya Waqfi, Danielle A Rankin, Rana Talj, Lora Thomas, Kelly A Birdwell, Lauren Ezzell, Marcia Blair, Joan Eason, Rebekkah Varjabedian, Christian M Warren, Cynthia H Nochowicz, Eric C Olson, Joshua D Simmons, Sandra Yoder, Madeline Guy, Isaac Thomsen, James D Chappell, Spyros A Kalams, Natasha B Halasa

Journal: Transpl Infect Dis

PubMed ID: 34905653

Doi: 10.1111/tid.13772

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Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile

Authors: Daniel Rehling, Emma Rose Scaletti, Inna Rozman Grinberg, Daniel Lundin, Margareta Sahlin, Anders Hofer, Britt-Marie Sjöberg, Pål Stenmark

Journal: Biochemistry

PubMed ID: 34941255

Doi: 10.1021/acs.biochem.1c00503

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Isolation of TCR genes with tumor-killing activity from tumor-infiltrating and circulating lymphocytes in a tumor rejection cynomolgus macaque model

Authors: Koji Terada, Kenta Kondo, Hirohito Ishigaki, Ayaka Nagashima, Hiroki Satooka, Seiji Nagano, Kyoko Masuda, Teruhisa Kawamura, Takako Hirata, Kazumasa Ogasawara, Yasushi Itoh, Hiroshi Kawamoto, Yasutoshi Agata

Journal: Mol Ther Oncolytics

PubMed ID: 35024435

Doi: 10.1016/j.omto.2021.12.003

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A Highly Conserved Peptide Vaccine Candidate Activates Both Humoral and Cellular Immunity Against SARS-CoV-2 Variant Strains

Authors: Fengxia Gao, Jingjing Huang, Tingting Li, Chao Hu, Meiying Shen, Song Mu, Feiyang Luo, Shuyi Song, Yanan Hao, Wang Wang, Xiaojian Han, Chen Qian, Yingming Wang, Ruixin Wu, Luo Li, Shenglong Li, Aishun Jin

Journal: Front Immunol

PubMed ID: 34950151

Doi: 10.3389/fimmu.2021.789905

Products & Services: Proteins, Expression, Isolation and Analysis

LncRNA FOXP4-AS1 Promotes the Progression of Esophageal Squamous Cell Carcinoma by Interacting With MLL2/H3K4me3 to Upregulate FOXP4

Authors: Yunfeng Niu, Gaoyan Wang, Yan Li, Wei Guo, Yanli Guo, Zhiming Dong

Journal: Front Oncol

PubMed ID: 34970490

Doi: 10.3389/fonc.2021.773864

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-Encoding Protein Is the Only Chemoreceptor That Regulates Chemoattraction toward the Broad Antibacterial Agent Formic Acid

Authors: Hao Wang, Mengqi Zhang, Yujuan Xu, Renjie Zong, Nan Xu, Minliang Guo

Journal: Biology (Basel)

PubMed ID: 34943260

Doi: 10.3390/biology10121345

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Nuclear Receptor Interacting Protein-2 Mediates the Stabilization and Activation of β-Catenin During Podocyte Injury

Authors: Qing Hou, Weibo Le, Shuyan Kan, Jinsong Shi, Yue Lang, Zhihong Liu, Zhaohong Chen

Journal: Front Cell Dev Biol

PubMed ID: 35004680

Doi: 10.3389/fcell.2021.781792

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ASCVac-1, a Multi-Peptide Chimeric Vaccine, Protects Mice Against Infection

Authors: Ana Clara Gazzinelli-Guimarães, Denise Silva Nogueira, Chiara Cássia Oliveira Amorim, Fabrício Marcus Silva Oliveira, Anderson Coqueiro-Dos-Santos, Samuel Alexandre Pimenta Carvalho, Lucas Kraemer, Fernando Sérgio Barbosa, Vanessa Gomes Fraga, Flaviane Vieira Santos, Joseane Camilla de Castro, Remo Castro Russo, Milena Apetito Akamatsu, Paulo Lee Ho, Maria Elena Bottazzi, Peter J Hotez, Bin Zhan, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara

Journal: Front Immunol

PubMed ID: 34992603

Doi: 10.3389/fimmu.2021.788185

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Protein acetylation regulates xylose metabolism during adaptation of Saccharomyces cerevisiae

Authors: Yong-Shui Tan, Li Wang, Ying-Ying Wang, Qi-En He, Zhi-Hua Liu, Zhen Zhu, Kai Song, Bing-Zhi Li, Ying-Jin Yuan

Journal: Biotechnol Biofuels

PubMed ID: 34920742

Doi: 10.1186/s13068-021-02090-x

Products & Services: Proteins, Expression, Isolation and Analysis

Boosting Vaccine-Elicited Respiratory Mucosal and Systemic COVID-19 Immunity in Mice With the Oral

Authors: Jianqing Xu, Zhihong Ren, Kangli Cao, Xianping Li, Jing Yang, Xuelian Luo, Lingyan Zhu, Xiangwei Wang, Longfei Ding, Junrong Liang, Dong Jin, Tingting Yuan, Lianfeng Li, Jianguo Xu

Journal: Front Nutr

PubMed ID: 35004816

Doi: 10.3389/fnut.2021.789242

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New lessons on TDP-43 from old N furzeri killifish

Authors: Alexandra Louka, Sara Bagnoli, Jakob Rupert, Benjamin Esapa, Gian Gaetano Tartaglia, Alessandro Cellerino, Annalisa Pastore, Eva Terzibasi Tozzini

Journal: Aging Cell

PubMed ID: 34939315

Doi: 10.1111/acel.13517

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Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses

Authors: Belén Aparicio, Noelia Casares, Josune Egea, Marta Ruiz, Diana Llopiz, Sheila Maestro, Cristina Olagüe, Gloria González-Aseguinolaza, Cristian Smerdou, Ascensión López-Díaz de Cerio, Susana Inogés, Felipe Prósper, José R Yuste, Francisco Carmona-Torre, Gabriel Reina, Juan J Lasarte, Pablo Sarobe

Journal: Emerg Microbes Infect

PubMed ID: 34538222

Doi: 10.1080/22221751.2021.1978823

Products & Services: Mammalian Expression

Icariin inhibits the expression of IL-1β, IL-6 and TNF-α induced by OGD/R through the IRE1/XBP1s pathway in microglia

Authors: Zhen-Tao Mo, Jie Zheng, Yu-Ling Liao

Journal: Pharm Biol

PubMed ID: 34711127

Doi: 10.1080/13880209.2021.1991959

Products & Services: Plasmid DNA Preparation

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