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Waning antibody levels after COVID-19 vaccination with mRNA Comirnaty and inactivated CoronaVac vaccines in blood donors, Hong Kong, April 2020 to October 2021

Authors: Shirley Ll Kwok, Samuel Ms Cheng, Jennifer Ns Leung, Kathy Leung, Cheuk-Kwong Lee, Js Malik Peiris, Joseph T Wu

Journal: Euro Surveill

PubMed ID: 35027105

Doi: 10.2807/1560-7917.ES.2022.27.2.2101197

Products & Services: Proteins, Expression, Isolation and Analysis

Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses

Authors: Bo Wang, Shuang Li, Yongbo Qiao, Yu Fu, Jiaojiao Nie, Shun Jiang, Xin Yao, Yi Pan, Linye Zhao, Congmei Wu, Yuhua Shi, Yuhe Yin, Yaming Shan

Journal: J Nanobiotechnology

PubMed ID: 35012571

Doi: 10.1186/s12951-021-01229-0

Products & Services: Codon Optimization

K-edge anomalous SAXS for protein solution structure modeling

Authors: Karman Virk, Kento Yonezawa, Komal Choukate, Lucky Singh, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35102886

Doi: 10.1107/S205979832101247X

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Genome-wide identification and expression pattern analysis of the TCP transcription factor family in

Authors: Li Yu, Qiangwen Chen, Jiarui Zheng, Feng Xu, Jiabao Ye, Weiwei Zhang, Yongling Liao, Xiaoyan Yang

Journal: Plant Signal Behav

PubMed ID: 35068346

Doi: 10.1080/15592324.2021.1994248

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Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells

Authors: Fei Liao, Jing Zhang, Yangyang Hu, Alireza Hassani Najafabadi, James J Moon, Max S Wicha, Bashir Kaspo, Joel Whitfield, Alfred E Chang, Qiao Li

Journal: Cancer Immunol Immunother

PubMed ID: 35098344

Doi: 10.1007/s00262-021-03129-6

Products & Services: Recombinant Proteins

miR-223 in exosomes from bone marrow mesenchymal stem cells ameliorates rheumatoid arthritis via downregulation of NLRP3 expression in macrophages

Authors: Ying Huang, Daomin Lu, Wukai Ma, Jun Liu, Qiaoyi Ning, Fang Tang, Long Li

Journal: Mol Immunol

PubMed ID: 35042119

Doi: 10.1016/j.molimm.2022.01.002

Products & Services: Gene Synthesis

A Pig-a conditional knock-out mice model mediated by Vav-iCre: stable GPI-deficient and mild hemolysis

Authors: Yingying Chen, Hui Liu, Lijie Zeng, Liyan Li, Dan Lu, Zhaoyun Liu, Rong Fu

Journal: Exp Hematol Oncol

PubMed ID: 35033195

Doi: 10.1186/s40164-022-00254-5

Products & Services: Proteins, Expression, Isolation and Analysis

A Pig-a conditional knock-out mice model mediated by Vav-iCre: stable GPI-deficient and mild hemolysis

Authors: Yingying Chen, Hui Liu, Lijie Zeng, Liyan Li, Dan Lu, Zhaoyun Liu, Rong Fu

Journal: Exp Hematol Oncol

PubMed ID: 35033195

Doi: 10.1186/s40164-022-00254-5

Products & Services: Proteins, Expression, Isolation and Analysis

Bioinformatics based discovery of new keratinases in protease family M36

Authors: Jingwen Qiu, Kristian Barrett, Casper Wilkens, Anne S Meyer

Journal: N Biotechnol

PubMed ID: 35032710

Doi: 10.1016/j.nbt.2022.01.004

Products & Services: Plasmid DNA Preparation

Clinical Potential of lncRNA PPP1R26-AS1 in Breast Cancer and Its Contribution to Cancer Progression

Authors: Shuping Zhou, Shaoli Zhang, Hui Zhang, Junxia Ma, Huangzhen Dai, Lili Qu, Meixiang Zhou

Journal: Mol Biotechnol

PubMed ID: 35064892

Doi: 10.1007/s12033-022-00452-w

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Antibody Responses after SARS-CoV-2 Vaccination in Patients with Liver Diseases

Authors: Athanasios-Dimitrios Bakasis, Kleopatra Bitzogli, Dimitrios Mouziouras, Abraham Pouliakis, Maria Roumpoutsou, Andreas V Goules, Theodoros Androutsakos

Journal: Viruses

PubMed ID: 35215801

Doi: 10.3390/v14020207

Antibody Responses after SARS-CoV-2 Vaccination in Patients with Liver Diseases

Authors: Athanasios-Dimitrios Bakasis, Kleopatra Bitzogli, Dimitrios Mouziouras, Abraham Pouliakis, Maria Roumpoutsou, Andreas V Goules, Theodoros Androutsakos

Journal: Viruses

PubMed ID: 35215801

Doi: 10.3390/v14020207

Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome

Authors: Juan Manuel Orozco Rodriguez, Ewa Krupinska, Hanna Wacklin-Knecht, Wolfgang Knecht

Journal: Nucleosides Nucleotides Nucleic Acids

PubMed ID: 35094635

Doi: 10.1080/15257770.2021.2023749

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Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI9 norovirus, as revealed by structural analysis

Authors: Tomomi Kimura-Someya, Miyuki Kato-Murayama, Kazushige Katsura, Naoki Sakai, Kazutaka Murayama, Kazuharu Hanada, Mikako Shirouzu, Yuichi Someya

Journal: FEBS Open Bio

PubMed ID: 35038379

Doi: 10.1002/2211-5463.13370

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Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants

Authors: Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran

Journal: Viruses

PubMed ID: 35215823

Doi: 10.3390/v14020230

Products & Services: Recombinant Proteins

Preparation of Edible Films with and Lactobionic Acid Produced by Sweet Whey Fermentation

Authors: Sara Sáez-Orviz, Ismael Marcet, Manuel Rendueles, Mario Díaz

Journal: Membranes (Basel)

PubMed ID: 35207037

Doi: 10.3390/membranes12020115

Products & Services: Proteins, Expression, Isolation and Analysis

Antibody response following SARS-CoV-2 vaccination among patients with type 2 diabetes mellitus: A systematic review

Authors: Nanny Natalia M Soetedjo, Maria Riastuti Iryaningrum, Sherly Lawrensia, Hikmat Permana

Journal: Diabetes Metab Syndr

PubMed ID: 35104750

Doi: 10.1016/j.dsx.2022.102406

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Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses primed by an injected vaccine

Authors: Jacob Pitcovski, Nady Gruzdev, Anna Abzach, Chen Katz, Ran Ben-Adiva, Michal Brand-Shwartz, Itamar Yadid, Einav Ratzon-Ashkenazi, Ken Emquies, Hadasa Israeli, Hadar Haviv, Irena Rapoport, Itai Bloch, Roy Shadmon, Zohar Eitan, Dalia Eliahu, Talia Hilel, Morris Laster, Sigal Kremer-Tal, Tamara Byk-Tennenbaum, Ehud Shahar

Journal: Vaccine

PubMed ID: 35078662

Doi: 10.1016/j.vaccine.2022.01.025

Products & Services: Proteins, Expression, Isolation and Analysis

LbCas12a-D156R Efficiently Edits Effector Binding Elements to Generate Canker-Resistant Citrus Plants

Authors: Hongge Jia, Yuanchun Wang, Hang Su, Xiaoen Huang, Nian Wang

Journal: Cells

PubMed ID: 35159125

Doi: 10.3390/cells11030315

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Neutralizing Activity and SARS-CoV-2 Vaccine mRNA Persistence in Serum and Breastmilk After BNT162b2 Vaccination in Lactating Women

Authors: Kee Thai Yeo, Wan Ni Chia, Chee Wah Tan, Chengsi Ong, Joo Guan Yeo, Jinyan Zhang, Su Li Poh, Amanda Jin Mei Lim, Kirsten Hui Zhi Sim, Nursyuhadah Sutamam, Camillus Jian Hui Chua, Salvatore Albani, Lin-Fa Wang, Mei Chien Chua

Journal: Front Immunol

PubMed ID: 35087517

Doi: 10.3389/fimmu.2021.783975

Products & Services: Mammalian Expression

Neutralizing Activity and SARS-CoV-2 Vaccine mRNA Persistence in Serum and Breastmilk After BNT162b2 Vaccination in Lactating Women

Journal: Front Immunol

PubMed ID: 35087517

Doi: 10.3389/fimmu.2021.783975

Products & Services: Mammalian Expression

The Linker Region Promotes Activity and Binding Efficiency of Modular LPMO towards Polymeric Substrate

Authors: Aishwarya Srivastava, Pragya Nagar, Sumit Rathore, Nidhi Adlakha

Journal: Microbiol Spectr

PubMed ID: 35080440

Doi: 10.1128/spectrum.02697-21

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CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA

Authors: Simin Chen, Zhaoyu Zhang, Baoxin Zhang, Qing Huang, Yi Liu, Yi Qiu, Xinmiao Long, Minghua Wu, Zuping Zhang

Journal: Int J Biol Sci

PubMed ID: 35002529

Doi: 10.7150/ijbs.66114

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Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice

Authors: Yi Zhang, Mufan Ji, Zhenyang Gu, Wenlong Pei, Jun Zhu, Qian Wu, Lei Li, Zhan Zhang

Journal: Toxicology

PubMed ID: 34979169

Doi: 10.1016/j.tox.2021.153088

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Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin

Authors: Favian A Liu, Negar Ardabili, Izaiah Brown, Harmain Rafi, Clarice Cook, Rodanthi Nikopoulou, Arianna Lopez, Shouzhong Zou, Matthew R Hartings, Alexander G Zestos

Journal: J Electrochem Soc

PubMed ID: 35185166

Doi: 10.1149/1945-7111/ac4aae

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Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates

Authors: Stéphane Pillet, Prabhu S Arunachalam, Guadalupe Andreani, Nadia Golden, Jane Fontenot, Pyone Pyone Aye, Katharina Röltgen, Gabrielle Lehmicke, Philipe Gobeil, Charlotte Dubé, Sonia Trépanier, Nathalie Charland, Marc-André D'Aoust, Kasi Russell-Lodrigue, Christopher Monjure, Robert V Blair, Scott D Boyd, Rudolf P Bohm, Jay Rappaport, François Villinger, Nathalie Landry, Bali Pulendran, Brian J Ward

Journal: Cell Mol Immunol

PubMed ID: 34983950

Doi: 10.1038/s41423-021-00809-2

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Evolutionary Origin of the Carotenoid Cleavage Oxygenase Family in Plants and Expression of Pepper Genes in Response to Abiotic Stresses

Authors: Yixiu Yao, Li Jia, Yuan Cheng, Meiying Ruan, Qingjing Ye, Rongqing Wang, Zhuping Yao, Guozhi Zhou, Jia Liu, Jiahong Yu, Peng Zhang, Yuhe Yin, Weiping Diao, Hongjian Wan

Journal: Front Plant Sci

PubMed ID: 35126418

Doi: 10.3389/fpls.2021.792832

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Improved yield, stability, and cleavage reaction of a novel tobacco etch virus protease mutant

Authors: Sergio Enríquez-Flores, José Ignacio De la Mora-De la Mora, Luis Antonio Flores-López, Nallely Cabrera, Cynthia Fernández-Lainez, Gloria Hernández-Alcántara, Carlos Enrique Guerrero-Beltrán, Gabriel López-Velázquez, Itzhel García-Torres

Journal: Appl Microbiol Biotechnol

PubMed ID: 35092453

Doi: 10.1007/s00253-022-11786-5

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N-glycolylneuraminic acid binding of avian and equine H7 influenza A viruses

Authors: Cindy M Spruit, Xueyong Zhu, Ilhan Tomris, María Ríos Carrasco, Alvin X Han, Frederik Broszeit, Roosmarijn van der Woude, Kim M Bouwman, Michel M T Luu, Keita Matsuno, Yoshihiro Sakoda, Colin A Russell, Ian A Wilson, Geert-Jan Boons, Robert P de Vries

Journal: J Virol

PubMed ID: 35044215

Doi: 10.1128/jvi.02120-21

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pVHL-mediated SMAD3 degradation suppresses TGF-β signaling

Authors: Jun Zhou , Yasamin Dabiri , Rodrigo A Gama-Brambila, Shahrouz Ghafoory , Mukaddes Altinbay , Arianeb Mehrabi , Mohammad Golriz , Biljana Blagojevic , Stefanie Reuter , Kang Han , Anna Seidel , Ivan Đikić , Stefan Wölfl , Xinlai Cheng

Journal: J Cell Biol

PubMed ID: 34860252

Doi: 10.1083/jcb.202012097

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Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay

Authors: Yusen Xiang, Guanglei Zhai, Yaozong Li, Mengge Wang, Xixiang Chen, Ruyu Wang, Hang Xie, Weidong Zhang, Guangbo Ge, Qian Zhang, Yechun Xu, Amedeo Caflisch, Jianrong Xu, Hongzhuan Chen, Lili Chen

Journal: Int J Biol Macromol

PubMed ID: 36521705

Doi: 10.1016/j.ijbiomac.2022.12.057

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Genomic distribution of signal transducer and activator of transcription (STAT) family in colorectal cancer

Authors: Yanping Hu, Yifen Shen, Yang Zhao, Ying Tang, Chao Liu, Yongchun Gu, Tao Yang, Yihang Shen

Journal: Hum Cell

PubMed ID: 36284066

Doi: 10.1007/s13577-022-00815-0

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Embracing enzyme promiscuity with activity-based compressed biosensing

Authors: Brandon Alexander Holt, Hong Seo Lim, Anirudh Sivakumar, Hathaichanok Phuengkham, Melanie Su, McKenzie Tuttle, Yilin Xu, Haley Liakakos, Peng Qiu, Gabriel A Kwong

Journal: Cell Rep Methods

PubMed ID: 36814844

Doi: 10.1016/j.crmeth.2022.100372

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The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection

Authors: Mathew P Kirby, Ciara Stevenson, Liam J Worrall, Yihang Chen, Christina Young, Jisoo Youm, Natalie C J Strynadka, Douglas W Allan, Eric Jan

Journal: J Virol

PubMed ID: 35019716

Doi: 10.1128/JVI.01330-21

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In silico, in vitro and in vivo safety evaluation of Limosilactobacillus reuteri strains ATCC PTA-126787 & ATCC PTA-126788 for potential probiotic applications

Authors: Dharanesh Gangaiah, Shrinivasrao P Mane, Nilesh R Tawari, Nallakannu Lakshmanan, Valerie Ryan, Alyssa Volland, Dwi Susanti, Milind Patel, Abraham Abouzeid, Emily B Helmes, Arvind Kumar

Journal: PLoS ONE

PubMed ID: 35081129

Doi: 10.1371/journal.pone.0262663

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Catalase () Gene Family in Wheat ( L): Evolution, Expression Pattern and Function Analysis

Authors: Yan Zhang, Lanjie Zheng, Liu Yun, Li Ji, Guanhui Li, Manchun Ji, Yong Shi, Xu Zheng

Journal: Int J Mol Sci

PubMed ID: 35008967

Doi: 10.3390/ijms23010542

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SMURF2 phosphorylation at Thr249 modifies glioma stemness and tumorigenicity by regulating TGF-β receptor stability

Authors: Manami Hiraiwa, Kazuya Fukasawa, Takashi Iezaki, Hemragul Sabit, Tetsuhiro Horie, Kazuya Tokumura, Sayuki Iwahashi, Misato Murata, Masaki Kobayashi, Akane Suzuki, Gyujin Park, Katsuyuki Kaneda, Tomoki Todo, Atsushi Hirao, Mitsutoshi Nakada, Eiichi Hinoi

Journal: Commun Biol

PubMed ID: 35017630

Doi: 10.1038/s42003-021-02950-0

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Preclinical Evaluation of Chicken Egg Yolk Antibody (IgY) Anti-RBD Spike SARS-CoV-2-A Candidate for Passive Immunization against COVID-19

Authors: Hendris Wongso, Isa Mahendra, Wyanda Arnafia, Idar Idar, Muhammad Yusuf, Arifudin Achmad, Holis A Holik, Ahmad Kurniawan, Iim Halimah, Maula E Sriyani, Teguh H A Wibawa, Muhamad B Febrian, Yanuar Setiadi, Eva M Widyasari, Isti Daruwati, Crhisterra E Kusumaningrum, Toto Subroto

Journal: Vaccines (Basel)

PubMed ID: 35062789

Doi: 10.3390/vaccines10010128

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Engineering His-Tagged Senecavirus A for One-Step Purification of Viral Antigens

Authors: Junhao Fan, Peiyu Xiao, Dongni Kong, Xinran Liu, Liang Meng, Tongqing An, Xuehui Cai, Haiwei Wang, Li Yu

Journal: Vaccines (Basel)

PubMed ID: 35214628

Doi: 10.3390/vaccines10020170

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Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells

Authors: Lakshana Sreenivasan, Ling Vicky Li, Pascal Leclair, Chinten James Lim

Journal: Cells

PubMed ID: 35159191

Doi: 10.3390/cells11030381

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OsMYB103 is essential for tapetum degradation in rice

Authors: Ting Lei, Lisha Zhang, Ping Feng, Yang Liu, Wuzhong Yin, Lina Shang, Guanghua He, Nan Wang

Journal: Theor Appl Genet

PubMed ID: 35018498

Doi: 10.1007/s00122-021-04007-6

Products & Services: Proteins, Expression, Isolation and Analysis

Exogenous Production of N-acetylmuramyl-L Alanine Amidase (LysM2) from Siphoviridae Phage Affecting Anti-Gram-Negative Bacteria: Evaluation of Its Structure and Function

Authors: Morteza Miri, Sepideh Yazdianpour, Shamsozoha Abolmaali, Shakiba Darvish Alipour Astaneh

Journal: Avicenna J Med Biotechnol

PubMed ID: 35509364

Doi: 10.18502/ajmb.v14i1.8169

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Reduced DNAJC3 Expression Affects Protein Translocation across the ER Membrane and Attenuates the Down-Modulating Effect of the Translocation Inhibitor Cyclotriazadisulfonamide

Authors: Eva Pauwels, Becky Provinciael, Anita Camps, Enno Hartmann, Kurt Vermeire

Journal: Int J Mol Sci

PubMed ID: 35054769

Doi: 10.3390/ijms23020584

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Dimensionless parameter predicts bacterial prodrug success

Authors: Brandon Alexander Holt, McKenzie Tuttle, Yilin Xu, Melanie Su, Joachim J Røise, Xioajian Wang, Niren Murthy, Gabriel A Kwong

Journal: Mol Syst Biol

PubMed ID: 35005851

Doi: 10.15252/msb.202110495

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Immunogenicity of a recombinant VSV-Vectored SARS-CoV vaccine induced robust immunity in rhesus monkeys after single-dose immunization

Authors: Dan Shan, Xiaoyan Tang, Renqiang Liu, Dan Pan, Xijun Wang, Jinying Ge, Zhiyuan Wen, Zhigao Bu

Journal: Virol Sin

PubMed ID: 35234625

Doi: 10.1016/j.virs.2022.01.002

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Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors

Authors: Daichao Wu, Alexander Kolesnikov, Rui Yin, Johnathan D Guest, Ragul Gowthaman, Anton Shmelev, Yana Serdyuk, Dmitry V Dianov, Grigory A Efimov, Brian G Pierce, Roy A Mariuzza

Journal: Nat Commun

PubMed ID: 35013235

Doi: 10.1038/s41467-021-27669-8

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Selective Coimmobilization of His-Tagged Enzymes on Yttrium-Stabilized Zirconia-Based Membranes for Continuous Asymmetric Bioreductions

Authors: Daniel Andrés-Sanz, Eleftheria Diamanti, Desirè Di Silvo, Jonas Gurauskis, Fernando López-Gallego

Journal: ACS Appl Mater Interfaces

PubMed ID: 35020352

Doi: 10.1021/acsami.1c20738

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Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity

Authors: Xiufei Chen, Wenjie Zhou, Ren-Hua Song, Shuang Liu, Shu Wang, Yujia Chen, Chao Gao, Chenxi He, Jianxiong Xiao, Lei Zhang, Tianxiang Wang, Peng Liu, Kunlong Duan, Zhouli Cheng, Chen Zhang, Jinye Zhang, Yiping Sun, Felix Jackson, Fei Lan, Yun Liu, Yanhui Xu, Justin Jong-Leong Wong, Pu Wang, Hui Yang, Yue Xiong, Tong Chen, Yan Li, Dan Ye

Journal: Sci Adv

PubMed ID: 35080973

Doi: 10.1126/sciadv.abl5220

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Impairing RAGE signaling promotes survival and limits disease pathogenesis following SARS-CoV-2 infection in mice

Authors: Forrest Jessop, Benjamin Schwarz, Dana Scott, Lydia M Roberts, Eric Bohrnsen, John R Hoidal, Catharine M Bosio

Journal: JCI Insight

PubMed ID: 35076028

Doi: 10.1172/jci.insight.155896

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Myricetin Allosterically Inhibits the Dengue NS2B-NS3 Protease by Disrupting the Active and Locking the Inactive Conformations

Authors: Mei Dang, Liangzhong Lim, Amrita Roy, Jianxing Song

Journal: ACS Omega

PubMed ID: 35097276

Doi: 10.1021/acsomega.1c05569

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A combination of multiple autoantibodies is associated with the risk of Alzheimer's disease and cognitive impairment

Authors: Sung-Mi Shim, Young Ho Koh, Jong-Hoon Kim, Jae-Pil Jeon

Journal: Sci Rep

PubMed ID: 35079008

Doi: 10.1038/s41598-021-04556-2

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Protein Interactome Analysis of the Type IX Secretion System Identifies PorW as the Missing Link between the PorK/N Ring Complex and the Sov Translocon

Authors: Dhana G Gorasia, Ignacio Lunar Silva, Catherine A Butler, Maïalène Chabalier, Thierry Doan, Eric Cascales, Paul D Veith, Eric C Reynolds

Journal: Microbiol Spectr

PubMed ID: 35019767

Doi: 10.1128/spectrum.01602-21

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Multifunctional liposomal nanostructure-mediated siRNA/bortezomib co-delivery for SHARP1 knockdown in MLL-AF6 acute myeloid leukemia

Authors: Sameh A Mohammed, Yang Ju

Journal: Biomater Adv

PubMed ID: 35577689

Doi: 10.1016/j.msec.2022.112663

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EID1 plays a protective role in early-onset pre-eclampsia via promoting proliferation and invasion in trophoblast cells

Authors: Ying Li, Jiuxiang Feng, Yue Bian, Wei Cheng, Chong Qiao

Journal: Folia Histochem Cytobiol

PubMed ID: 35038162

Doi: 10.5603/FHC.a2022.0001

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Control of subunit stoichiometry in single-chain MspA nanopores

Authors: Mikhail Pavlenok, Luning Yu, Dominik Herrmann, Meni Wanunu, Michael Niederweis

Journal: Biophys J

PubMed ID: 35101416

Doi: 10.1016/j.bpj.2022.01.022

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Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models

Authors: Aviral Kumar, Amarnath Singam, Guruprasadh Swaminathan, Naresh Killi, Naveen Kumar Tangudu, Jedy Jose, Rathna Gundloori Vn, Lekha Dinesh Kumar

Journal: Nanoscale

PubMed ID: 34913453

Doi: 10.1039/d1nr04411g

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Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging

Authors: Manning Y Huang, Meenakshi B Joshi, Michael J Boucher, Sujin Lee, Liza C Loza, Elizabeth A Gaylord, Tamara L Doering, Hiten D Madhani

Journal: Genetics

PubMed ID: 34791226

Doi: 10.1093/genetics/iyab180

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Improved myocardial performance in infarcted rat heart by injection of disulfide-cross-linked chitosan hydrogels loaded with basic fibroblast growth factor

Authors: Bo Fu, Xiaobei Wang, Zhengda Chen, Nan Jiang, Zhigang Guo, Yuhui Zhang, Shaopeng Zhang, Xiankun Liu, Li Liu

Journal: J Mater Chem B

PubMed ID: 35014648

Doi: 10.1039/d1tb01961a

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Lipoxin A and its analog attenuate high fat diet-induced atherosclerosis via Keap1/Nrf2 pathway

Authors: Fen Xu, Jiamin Zhang, Xiaoyan Zhou, Hua Hao

Journal: Exp Cell Res

PubMed ID: 35026282

Doi: 10.1016/j.yexcr.2022.113025

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Molecular Characterization of Mg-Chelatase CHLI Subunit in Pea ( L)

Authors: Cai-Jun Wu, Jie Wang, Jun Zhu, Jing Ren, You-Xin Yang, Tao Luo, Lu-Xi Xu, Qing-Hong Zhou, Xu-Feng Xiao, Yu-Xin Zhou, Sha Luo

Journal: Front Plant Sci

PubMed ID: 35145539

Doi: 10.3389/fpls.2022.821683

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Molecular Characterization of Mg-Chelatase CHLI Subunit in Pea ( L)

Authors: Cai-Jun Wu, Jie Wang, Jun Zhu, Jing Ren, You-Xin Yang, Tao Luo, Lu-Xi Xu, Qing-Hong Zhou, Xu-Feng Xiao, Yu-Xin Zhou, Sha Luo

Journal: Front Plant Sci

PubMed ID: 35145539

Doi: 10.3389/fpls.2022.821683

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The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential

Authors: Lu Wang, Xi Wang, Xiying Lv, Qiushuo Jin, Hongcai Shang, Chih-Chen Wang, Lei Wang

Journal: Redox Biol

PubMed ID: 35077997

Doi: 10.1016/j.redox.2022.102244

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Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test

Authors: Qiao Wang, Lili Feng, Haohai Zhang, Juehua Gao, Changchuin Mao, Esther Landesman-Bollag, Gustavo Mostoslavsky, Justin M Lunderberg, Weina Zheng, Shushun Hao, Wenda Gao

Journal: Antib Ther

PubMed ID: 35146332

Doi: 10.1093/abt/tbac004

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Severity of adverse reactions is associated with T-cell response in mRNA-1273 vaccinated health care workers

Authors: Hanna Klingel, Maike Lauen, Alexander Krüttgen, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223673

Doi: 10.7774/cevr.2022.11.1.121

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Inhibiting L1CAM Reverses Cisplatin Resistance of Triple Negative Breast Cancer Cells by Blocking AKT Signaling Pathway

Authors: Lu-Yao Zhang, Zhi-Xin Shen, Lu Guo

Journal: Cancer Invest

PubMed ID: 35040385

Doi: 10.1080/07357907.2021.2016801

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Solid-Phase Extraction Approaches for Improving Oligosaccharide and Small Peptide Identification with Liquid Chromatography-High-Resolution Mass Spectrometry: A Case Study on Proteolyzed Almond Extract

Authors: Yu-Ping Huang, Randall C Robinson, Fernanda Furlan Goncalves Dias, Juliana Maria Leite Nobrega de Moura Bell, Daniela Barile

Journal: Foods

PubMed ID: 35159490

Doi: 10.3390/foods11030340

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Rational Development and Characterization of a Ubiquitin Variant with Selectivity for Ubiquitin C-Terminal Hydrolase L3

Authors: Chad S Hewitt, Chittaranjan Das, Daniel P Flaherty

Journal: Biomolecules

PubMed ID: 35053210

Doi: 10.3390/biom12010062

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Protection and Alleviated Inflammation Induced by Virus-like Particle Vaccines Containing MSP-8, MSP-9 and RAP1

Authors: Su-Hwa Lee, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 35214662

Doi: 10.3390/vaccines10020203

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Protection and Alleviated Inflammation Induced by Virus-like Particle Vaccines Containing MSP-8, MSP-9 and RAP1

Authors: Su-Hwa Lee, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Vaccines (Basel)

PubMed ID: 35214662

Doi: 10.3390/vaccines10020203

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Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations

Authors: Anju Jaiswal, D Dash, Rashmi Singh

Journal: Toxicol Appl Pharmacol

PubMed ID: 34998855

Doi: 10.1016/j.taap.2021.115861

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Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response

Authors: Satoshi Shimizu, Yoichi Sunagawa, Naruto Hajika, Natsumi Yorimitsu, Yasufumi Katanasaka, Masafumi Funamoto, Yusuke Miyazaki, Nurmila Sari, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto

Journal: Int J Biol Sci

PubMed ID: 35173540

Doi: 10.7150/ijbs.65664

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Heterologous Expression and Functional Characterization of CAP18 from

Authors: Mahla Nikpoor, Azadeh Lohrasbi-Nejad, Jafar Zolala

Journal: Rep Biochem Mol Biol

PubMed ID: 35291606

Doi: 10.52547/rbmb.10.4.622

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Activity-based protein profiling reveals dynamic substrate-specific cellulase secretion by saprotrophic basidiomycetes

Authors: Nicholas G S McGregor, Casper de Boer, Mikhaaeel Santos, Mireille Haon, David Navarro, Sybrin Schroder, Jean-Guy Berrin, Herman S Overkleeft, Gideon J Davies

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 35418096

Doi: 10.1186/s13068-022-02107-z

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GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus

Authors: Nitaya Indrawattana, Pisinee Aiumurai, Nawannaporn Sae-Lim, Watee Seesuay, Onrapak Reamtong, Manas Chongsa-Nguan, Wanpen Chaicumpa, Nitat Sookrung

Journal: Diagnostics (Basel)

PubMed ID: 35054302

Doi: 10.3390/diagnostics12010136

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Core-shell "loading-type" nanomaterials towards: Simultaneous imaging analysis of glutathione and microRNA

Authors: Lin-Lin Lu, Qin Zhang, Yu Gu, Xiang-Ling Li, Jing Jing Xie

Journal: Anal Chim Acta

PubMed ID: 35151402

Doi: 10.1016/j.aca.2022.339551

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Bioinformatics based discovery of new keratinases in protease family M36

Authors: Jingwen Qiu, Kristian Barrett, Casper Wilkens, Anne S Meyer

Journal: N Biotechnol

PubMed ID: 35032710

Doi: 10.1016/j.nbt.2022.01.004

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An Active Peptide-Based Packaging System to Improve the Freshness and Safety of Fish Products: A Case Study

Authors: Rosa Luisa Ambrosio, Marta Gogliettino, Bruna Agrillo, Yolande T R Proroga, Marco Balestrieri, Lorena Gratino, Daniela Cristiano, Gianna Palmieri, Aniello Anastasio

Journal: Foods

PubMed ID: 35159493

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Anti-aquaporin-4 immunoglobulin G colorimetric detection by silver nanoparticles

Authors: Akemi M Higa, Ariana S Moraes, Flávio M Shimizu, Raquel G Bueno, Luís A Peroni, Francisco T Strixino, Nise A C Sousa, Elenice Deffune, Ana Lívia C Bovolato, Osvaldo N Oliveira, Doralina G Brum, Fabio L Leite

Journal: Nanomedicine

PubMed ID: 35114406

Doi: 10.1016/j.nano.2022.102531

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Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Filamin C, Scy p 9

Authors: Xin-Rong He, Yang Yang, Shuai Kang, Ye-Xin Chen, Pei-Yi Zheng, Gui-Xia Chen, Xiao-Mei Chen, Min-Jie Cao, Tengchuan Jin, Guang-Ming Liu

Journal: J Agric Food Chem

PubMed ID: 35040643

Doi: 10.1021/acs.jafc.1c07922

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Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages

Authors: Fangfang Yu, Wenxia Tian, Jie Dong

Journal: Int Immunopharmacol

PubMed ID: 35045357

Doi: 10.1016/j.intimp.2021.108514

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Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment

Authors: Deepika Narayanan, Danyal Tahseen, Brooke R Bartley, Stephen A Moore, Rebecca Simonette, Peter L Rady, Stephen K Tyring

Journal: Virus Genes

PubMed ID: 35000075

Doi: 10.1007/s11262-021-01880-7

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Preparation of Edible Films with and Lactobionic Acid Produced by Sweet Whey Fermentation

Authors: Sara Sáez-Orviz, Ismael Marcet, Manuel Rendueles, Mario Díaz

Journal: Membranes (Basel)

PubMed ID: 35207037

Doi: 10.3390/membranes12020115

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Genome-wide identification and expression profile of YABBY genes in

Authors: Chengru Li, Na Dong, Liming Shen, Meng Lu, Junwen Zhai, Yamei Zhao, Lei Chen, Zhiting Wan, Zhongjian Liu, Hui Ren, Shasha Wu

Journal: PeerJ

PubMed ID: 35036123

Doi: 10.7717/peerj.12558

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Selection and T-cell antigenicity of synthetic long peptides derived from SARS-CoV-2

Authors: Katarzyna Piadel, Amin Haybatollahi, Angus George Dalgleish, Peter Lawrence Smith

Journal: J Gen Virol

PubMed ID: 35014605

Doi: 10.1099/jgv.0.001698

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Penetration of the SARS-CoV-2 Spike Protein across the Blood-Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing

Authors: Dániel Petrovszki, Fruzsina R Walter, Judit P Vigh, Anna Kocsis, Sándor Valkai, Mária A Deli, András Dér

Journal: Biomedicines

PubMed ID: 35052867

Doi: 10.3390/biomedicines10010188

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Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands

Authors: Ting Zhang, Minya Zhou, Heqing Cai, Kunning Yan, Yiwen Zha, Wenwen Zhuang, Jingyan Liang, Yong Cheng

Journal: Transgenic Res

PubMed ID: 35034272

Doi: 10.1007/s11248-021-00292-5

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Large inter-individual variability of cellular and humoral immunological responses to mRNA-1273 (Moderna) vaccination against SARS-CoV-2 in health care workers

Authors: Alexander Krüttgen, Gerhard Haase, Helga Haefner, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223670

Doi: 10.7774/cevr.2022.11.1.96

ROS-regulated phosphorylation of ITPKB by CAMK2G drives cisplatin resistance in ovarian cancer

Authors: Jie Li, Cuimiao Zheng, Mingshuo Wang, Anna D Umano, Qingyuan Dai, Chunyu Zhang, Hua Huang, Qing Yang, Xianzhi Yang, Jingyi Lu, Wenfeng Pan, Bo Li, Shuzhong Yao, Chaoyun Pan

Journal: Oncogene

PubMed ID: 35039634

Doi: 10.1038/s41388-021-02149-x

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Investigating Constraints Along the Plant Secretory Pathway to Improve Production of a SARS-CoV-2 Spike Vaccine Candidate

Authors: Emmanuel Margolin, Matthew Verbeek, Warren de Moor, Ros Chapman, Ann Meyers, Georgia Schäfer, Anna-Lise Williamson, Edward Rybicki

Journal: Front Plant Sci

PubMed ID: 35058959

Doi: 10.3389/fpls.2021.798822

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Heterogeneous Ribonucleoprotein A1 (hnRNPA1) Interacts with the Nucleoprotein of the Influenza a Virus and Impedes Virus Replication

Authors: Ramandeep Kaur, Jyoti Batra, Olga Stuchlik, Matthew S Reed, Jan Pohl, Suryaprakash Sambhara, Sunil Kumar Lal

Journal: Viruses

PubMed ID: 35215793

Doi: 10.3390/v14020199

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Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation

Authors: María Teresa Bueno-Carrasco, Jorge Cuéllar, Marte I Flydal, César Santiago, Trond-André Kråkenes, Rune Kleppe, José R López-Blanco, Miguel Marcilla, Knut Teigen, Sara Alvira, Pablo Chacón, Aurora Martinez, José M Valpuesta

Journal: Nat Commun

PubMed ID: 35013193

Doi: 10.1038/s41467-021-27657-y

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Immune escape mutations selected by neutralizing antibodies in natural HIV-1 infection can alter coreceptor usage repertoire of the transmitted/founder virus

Authors: Manukumar Honnayakanahalli Marichannegowda, Hongshuo Song

Journal: Virology

PubMed ID: 35144109

Doi: 10.1016/j.virol.2022.01.010

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Human α-defensin 6 (HD6) suppresses CRC proliferation and metastasis through abolished EGF/EGFR signaling pathway

Authors: Po-Li Wei, Jang-Chun Lin, Chin-Sheng Hung, Precious Takondwa Makondi, Uyanga Batzorig, Tung-Cheng Chang, Chien-Yu Huang, Yu-Jia Chang

Journal: Int J Med Sci

PubMed ID: 34975297

Doi: 10.7150/ijms.64850

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Analysis of RNA-containing compartments by hybridization and proximity labeling in cultured human cells

Authors: Karen Yap, Tek Hong Chung, Eugene V Makeyev

Journal: STAR Protoc

PubMed ID: 35128480

Doi: 10.1016/j.xpro.2022.101139

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Cardiovascular-specific PSEN1 deletion leads to abnormalities in calcium homeostasis

Authors: Xiao-Wei Song, Feng Zhao, Jing Yang, Qing-Ning Yuan, Zhen-Yu Zeng, Ming Shen, Ying Tang, Mi Cao, Ya-Feng Shen, Song-Hua Li, Yong-Ji Yang, Hong Wu, Xian-Xian Zhao, Shu-Ting Hu

Journal: Cell Biol Int

PubMed ID: 34939719

Doi: 10.1002/cbin.11753

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Schistosome TRPML channels play a role in neuromuscular activity and tegumental integrity

Authors: Swarna Bais, Abigail Norwillo, Gordon Ruthel, De'Broski R Herbert, Bruce D Freedman, Robert M Greenberg

Journal: Biochimie

PubMed ID: 34990770

Doi: 10.1016/j.biochi.2021.12.018

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Genome-Wide Identification and Expression Profiles of Genes in L

Authors: Meng Lu, Xiang-Xiao Meng, Yi-Ming Zhang, Xue-Wen Zhu, Jun Li, Wei-Qiang Chen, Hui-Hua Wan, Si-Fan Wang, Xue Cao, Wei Sun, Yao-Lei Mi, Jun-Wen Zhai

Journal: Cannabis Cannabinoid Res

PubMed ID: 35020417

Doi: 10.1089/can.2021.0153

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A phage parasite deploys a nicking nuclease effector to inhibit viral host replication

Authors: Kristen N LeGault, Zachary K Barth, Peter DePaola, Kimberley D Seed

Journal: Nucleic Acids Res

PubMed ID: 35066583

Doi: 10.1093/nar/gkac002

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A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

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Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

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