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Time-Prolonged Release of Tumor-Targeted Protein-MMAE Nanoconjugates from Implantable Hybrid Materials

Authors: Naroa Serna, Aïda Falgàs, Annabel García-León, Ugutz Unzueta, Yáiza Núñez, Alejandro Sánchez-Chardi, Carlos Martínez-Torró, Ramón Mangues, Esther Vazquez, Isolda Casanova, Antonio Villaverde

Journal: Pharmaceutics

PubMed ID: 35057088

Doi: 10.3390/pharmaceutics14010192

Products & Services: Proteins, Expression, Isolation and Analysis

Optimization of Thymidine Kinase-Based Safety Switch for Neural Cell Therapy

Authors: Manon Locatelli, Flavien Delhaes, Ophélie Cherpin, Margaret E Black, Stéphanie Carnesecchi, Olivier Preynat-Seauve, Youssef Hibaoui, Karl-Heinz Krause

Journal: Cells

PubMed ID: 35159311

Doi: 10.3390/cells11030502

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Zika virus baculovirus-expressed envelope protein elicited humoral and cellular immunity in immunocompetent mice

Authors: Minna Shin, Kiju Kim, Hyo-Ji Lee, Rangyeon Lee, Yu-Jin Jung, Jeongho Park, Tae-Wook Hahn

Journal: Sci Rep

PubMed ID: 35027643

Doi: 10.1038/s41598-021-04713-7

Products & Services: Proteins, Expression, Isolation and Analysis

BrnQ-Type Branched-Chain Amino Acid Transporters Influence Bacillus anthracis Growth and Virulence

Authors: Soumita Dutta, Ileana D Corsi, Naomi Bier, Theresa M Koehler

Journal: MBio

PubMed ID: 35073743

Doi: 10.1128/mbio.03640-21

Products & Services: Proteins, Expression, Isolation and Analysis

Effects of the Chloroplast Fructose-1,6-Bisphosphate Aldolase Gene on Growth and Low-Temperature Tolerance of Tomato

Authors: Bingbing Cai, Yu Ning, Qiang Li, Qingyun Li, Xizhen Ai

Journal: Int J Mol Sci

PubMed ID: 35054921

Doi: 10.3390/ijms23020728

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Plant expression systems as an economical alternative for the production of iELISA coating antigen AHSV VP7

Authors: Shelley H Fearon, Susan J Dennis, Inga I Hitzeroth, Edward P Rybicki, Ann E Meyers

Journal: N Biotechnol

PubMed ID: 35114407

Doi: 10.1016/j.nbt.2022.01.009

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Hyperproduction of PHA copolymers containing high fractions of 4-hydroxybutyrate (4HB) by outer membrane-defected Halomonas bluephagenesis grown in bioreactors

Authors: Ziyu Wang, Yifei Zheng, Mengke Ji, Xu Zhang, Huan Wang, Yuemeng Chen, Qiong Wu, Guo-Qiang Chen

Journal: Microb Biotechnol

PubMed ID: 34978757

Doi: 10.1111/1751-7915.13999

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SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons

Authors: Hila Asraf, Milos Bogdanovic, Noa Gottesman, Israel Sekler, Elias Aizenman, Michal Hershfinkel

Journal: iScience

PubMed ID: 35118363

Doi: 10.1016/j.isci.2022.103751

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Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1

Authors: Qi Sun, Yufen Wang, Adam Officer, Brianna Pecknold, Garrett Lee, Olivier Harismendy, Jay S Desgrosellier

Journal: NPJ Breast Cancer

PubMed ID: 35027548

Doi: 10.1038/s41523-021-00375-w

Products & Services: Plasmid DNA Preparation

Proline-specific aminopeptidase P prevents replication-associated genome instability

Authors: Nicola Silva, Maikel Castellano-Pozo, Kenichiro Matsuzaki, Consuelo Barroso, Monica Roman-Trufero, Hannah Craig, Darren R Brooks, R Elwyn Isaac, Simon J Boulton, Enrique Martinez-Perez

Journal: PLoS Genet

PubMed ID: 35081133

Doi: 10.1371/journal.pgen.1010025

Products & Services: Proteins, Expression, Isolation and Analysis

Precise exogenous insertion and sequence replacements in poplar by simultaneous HDR overexpression and NHEJ suppression using CRISPR-Cas9

Authors: Ali Movahedi, Hui Wei, Xiaohong Zhou, Jake C Fountain, Zhong-Hua Chen, Zhiying Mu, Weibo Sun, Jiaxin Zhang, Dawei Li, Baozhu Guo, Rajeev K Varshney, Liming Yang, Qiang Zhuge

Journal: Hortic Res

PubMed ID: 36133672

Doi: 10.1093/hr/uhac154

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USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma

Authors: Yang Chen, Yin Zhao, Xiaojing Yang, Xianyue Ren, Shengyan Huang, Sha Gong, Xirong Tan, Junyan Li, Shiwei He, Yingqin Li, Xiaohong Hong, Qian Li, Cong Ding, Xueliang Fang, Jun Ma, Na Liu

Journal: Nat Commun

PubMed ID: 35079021

Doi: 10.1038/s41467-022-28158-2

Products & Services: Proteins, Expression, Isolation and Analysis

Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease

Authors: Lucía Barbier-Torres, Ben Murray, Jin Won Yang, Jiaohong Wang, Michitaka Matsuda, Aaron Robinson, Aleksandra Binek, Wei Fan, David Fernández-Ramos, Fernando Lopitz-Otsoa, Maria Luque-Urbano, Oscar Millet, Nirmala Mavila, Hui Peng, Komal Ramani, Roberta Gottlieb, Zhaoli Sun, Suthat Liangpunsakul, Ekihiro Seki, Jennifer E Van Eyk, Jose M Mato, Shelly C Lu

Journal: Nat Commun

PubMed ID: 35091576

Doi: 10.1038/s41467-022-28201-2

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Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes

Authors: Melody Gao, D Alex Johnson, Isabel M Piper, Hanna M Kodama, Justin E Svendsen, Elise Tahti, Frederick Longshore-Neate, Brandon Vogel, John M Antos, Jeanine F Amacher

Journal: Protein Sci

PubMed ID: 34939250

Doi: 10.1002/pro.4266

Products & Services: Proteins, Expression, Isolation and Analysis

A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca signalling through IP receptors

Authors: Andrew R Lavik, Karen S McColl, Fernanda O Lemos, Martijn Kerkhofs, Fei Zhong, Michael Harr, Daniela Schlatzer, Kozo Hamada, Katsuhiko Mikoshiba, Francesco Crea, Geert Bultynck, Martin D Bootman, Jan B Parys, Clark W Distelhorst

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 35026348

Doi: 10.1016/j.bbamcr.2021.119206

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MicroRNA analysis reveals the role of miR-214 in duck adipocyte differentiation

Authors: Laidi Wang, Xiaodan Hu, Shasha Wang, Chunyou Yuan, Zhixiu Wang, Guobin Chang, Guohong Chen

Journal: Anim Biosci

PubMed ID: 35073666

Doi: 10.5713/ab.21.0441

Products & Services: Proteins, Expression, Isolation and Analysis

Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant

Authors: Khadija Khan, Farina Karim, Sandile Cele, James Emmanuel San, Gila Lustig, Houriiyah Tegally, Yuval Rosenberg, Mallory Bernstein, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Nokuthula Ngcobo, Yoliswa Miya, Matilda Mazibuko, Ntombifuthi Mthabela, Zoey Mhlane, Nikiwe Mbatha, Jennifer Giandhari, Yajna Ramphal, Taryn Naidoo, Nithendra Manickchund, Nombulelo Magula, Salim Abdool Karim, Glenda Gray, Willem Hanekom, Anne von Gottberg, Ron Milo, Bernadett Gosnell, Richard Lessells, Tulio de Oliveira, Penny Moore, Yunus S Moosa, Alex Sigal

Journal: medrxiv

PubMed ID: 34981076

Doi: 10.1101/2021.12.27.21268439

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Quantitation of Trastuzumab and an Antibody to SARS-CoV-2 in Minutes Using Affinity Membranes in 96-Well Plates

Authors: Hui Yin Tan, Junyan Yang, Jacqueline C Linnes, Christopher J Welch, Merlin L Bruening

Journal: Anal Chem

PubMed ID: 34982935

Doi: 10.1021/acs.analchem.1c03654

Products & Services: Peptide Synthesis

Development of a radioiodinated thioflavin-T-Congo-red hybrid probe for diagnosis of systemic amyloidosis

Authors: Yoshie Haratake, Kohei Sano, Miki Tsuchiya, Kaori Minaki, Masayuki Munekane, Toshihide Yamasaki, Masayori Hagimori, Takahiro Mukai

Journal: Bioorg Med Chem

PubMed ID: 35033883

Doi: 10.1016/j.bmc.2021.116591

Products & Services: Proteins, Expression, Isolation and Analysis

A network of Gα signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF

Authors: Naincy R Chandan, Saji Abraham, Shuvasree SenGupta, Carole A Parent, Alan V Smrcka

Journal: Sci Signal

PubMed ID: 35041463

Doi: 10.1126/scisignal.abi9869

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Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma

Authors: Sofie Kirial Mørk, Mohammad Kadivar, Kalijn Fredrike Bol, Arianna Draghi, Marie Christine Wulff Westergaard, Signe Koggersbøl Skadborg, Nana Overgaard, Anders Bundgård Sørensen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Christina Westmose Yde, Thomas Trolle, Christian Garde, Jens Friis-Nielsen, Nis Nørgaard, Dennis Christensen, Jens Vindahl Kringelum, Marco Donia, Sine Reker Hadrup, Inge Marie Svane

Journal: Oncoimmunology

PubMed ID: 35036074

Doi: 10.1080/2162402X.2021.2023255

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Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide

Authors: Nathalie Vanderheijden, Annelies Stevaert, Jiexiong Xie, Xiaolei Ren, Cyril Barbezange, Sam Noppen, Isabelle Desombere, Bruno Verhasselt, Peter Geldhof, Nick Vereecke, Veerle Stroobants, Dayoung Oh, Merijn Vanhee, Lieve M J Naesens, Hans J Nauwynck

Journal: Front Immunol

PubMed ID: 35069571

Doi: 10.3389/fimmu.2021.790415

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Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

Authors: Algirdas Grevys, Rahel Frick, Simone Mester, Karine Flem-Karlsen, Jeannette Nilsen, Stian Foss, Kine Marita Knudsen Sand, Thomas Emrich, Jens Andre Alexander Fischer, Victor Greiff, Inger Sandlie, Tilman Schlothauer, Jan Terje Andersen

Journal: iScience

PubMed ID: 35118359

Doi: 10.1016/j.isci.2022.103746

Products & Services: Mutagenesis Services

CRISPR/Cas12a Technology Combined With RPA for Rapid and Portable SFTSV Detection

Authors: Mengqian Huang, Sihua Liu, Yanan Xu, Aqian Li, Wei Wu, Mifang Liang, Guoyu Niu, Zhiyun Wang, Tao Wang

Journal: Front Microbiol

PubMed ID: 35145502

Doi: 10.3389/fmicb.2022.754995

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Channelopathy-causing mutations in the S45A/S45B and HA/HB helices of KCa2.3 and KCa3.1 channels alter their apparent Ca2+ sensitivity

Authors: Razan Orfali, Young-Woo Nam, Hai Minh Nguyen, Mohammad Asikur Rahman, Grace Yang, Meng Cui, Heike Wulff, Miao Zhang

Journal: Cell Calcium

Doi: doi.org/10.1016/j.ceca.2022.102538

Products & Services: Mutagenesis Services

RBD conjugate vaccine with a built-in TLR1/2 agonist is highly immunogenic against SARS-CoV-2 and variants of concern

Authors: Shi-Hao Zhou 1 , Ru-Yan Zhang, Hai-Wei Zhang, Yan-Ling Liu, Yu Wen, Jian Wang, Yu-Ting Li, Zi-Wei You, Xu-Guang Yin, Hong Qiu, Rui Gong, Guang-Fu Yang, Jun Guo

Journal: Chem Commun (Camb)

PubMed ID: 35040862

Doi: 10.1039/d1cc06520c

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A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

Authors: Griffin M Schroeder, Chapin E Cavender , Maya E Blau, Jermaine L Jenkins, David H Mathews, Joseph E Wedekind

Journal: Nat Commun

PubMed ID: 35017488

Doi: 10.1038/s41467-021-27790-8

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Peptide ligand interaction with maltose-binding protein tagged to the calcitonin gene-related peptide receptor: the inhibitory role of receptor N-glycosylation

Authors: Sangmin Lee

Journal: Peptides

PubMed ID: 35007660

Doi: 10.1016/j.peptides.2022.170735

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Long Non-coding Antisense RNA DDIT4-AS1 Regulates Meningitic Escherichia coli-Induced Neuroinflammation by Promoting DDIT4 mRNA Stability

Authors: Bo Yang, Bojie Xu,Ruicheng Yang, Jiyang Fu, Liang Li, Dong Huo,Jiaqi Chen, Xiaopei Yang,Chen Tan,Huanchun Chen and Xiangru Wang

Journal: Mol Neurobiol

PubMed ID: 34985734

Doi: 10.1007/s12035-021-02690-6

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A VLP-Based Vaccine Candidate Protects Mice against Japanese Encephalitis Virus Infection

Authors: Limin Yang , Aibo Xiao , Hu Wang , Xiaojuan Zhang , Yuan Zhang , Yunlong Li, Yanqiu Wei , Wenjun Liu , Chuangfu Chen

Journal: Vaccines (Basel)

PubMed ID: 35214656

Doi: 10.3390/vaccines10020197

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Computer-Informed Engineering a New Class I Sesquiterpene Synthase JeSTS4 for the Synthesis of Unusual C10-(S)- Bicyclogermacrene

Authors: Xiaoguang Yan, Jiahui Zhou, Jianjun Ge, Weiguo Li, Dongmei Liang, Warispreet Singh, Gary Black, Shengxin Nie, Jian Liu, Meiqing Sun, Jianjun Qiao, and Meilan Huang

Journal: ACS catalysis

Doi: 10.1021/acscatal.2c00013

Products & Services: Proteins, Expression, Isolation and Analysis

The First FRET-Based RNA Aptamer NanoKit for Sensitively and Specifically Detecting c-di-GMP

Authors: Ya Gao , Yurui Xu , Yanyan Li , Kerong Chen , Xiaotong Wu , Yuhang Liu , Xuli Feng , Desheng Kong , Xinghai Ning

Journal: Nano Lett

PubMed ID: 34994567

Doi: 10.1021/acs.nanolett.1c03970

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Plasmodium falciparum Kelch13 and its artemisinin-resistant mutants assemble as hexamers in solution: a SAXS data-driven modelling study

Authors: Nainy Goel, Kanika Dhiman, Nidhi Kalidas, Anwesha Mukhopadhyay, Fnu Ashish, Souvik Bhattacharjee

Journal: FEBS J

PubMed ID: 35092154

Doi: 10.1111/febs.16378

Products & Services: Proteins, Expression, Isolation and Analysis

Overcoming tumor heterogeneity by ex vivo arming of T cells using multiple bispecific antibodies

Authors: Jeong A Park, Nai-Kong V Cheung

Journal: J Immunother Cancer

PubMed ID: 35086947

Doi: 10.1136/jitc-2021-003771

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Fukutin regulates tau phosphorylation and synaptic function: Novel properties of fukutin in neurons

Authors: Ryota Tsukui, Tomoko Yamamoto, Yukinori Okamura, Yoichiro Kato, Noriyuki Shibata

Journal: Neuropathology

PubMed ID: 35026860

Doi: 10.1111/neup.12797

Products & Services: PCR Cloning and Subcloning

Backbone NMR assignment of the nucleotide binding domain of the Bacillus subtilis ABC multidrug transporter BmrA in the post-hydrolysis state

Authors: Victor Hugo Pérez Carrillo, Dania Rose-Sperling, Mai Anh Tran, Christoph Wiedemann, Ute A Hellmich

Journal: Biomol NMR Assign

PubMed ID: 34988902

Doi: 10.1007/s12104-021-10063-2

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Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase

Authors: Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza, Ikechukwu Achilonu

Journal: Protein J

PubMed ID: 35083643

Doi: 10.1007/s10930-021-10037-2

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Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus

Authors: Liqi Liu, Zi Li, Jianfang Zhou, Jia Liu, Xiyan Li, Weijuan Huang, Ning Xiao, Dayan Wang

Journal: Influenza Other Respir Viruses

PubMed ID: 35037399

Doi: 10.1111/irv.12954

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Formation of β-Strand Oligomers of Antimicrobial Peptide Magainin 2 Contributes to Disruption of Phospholipid Membrane

Authors: Munehiro Kumashiro, Ryoga Tsuji, Shoma Suenaga, Koichi Matsuo

Journal: Membranes (Basel)

PubMed ID: 35207051

Doi: 10.3390/membranes12020131

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Inhibiting L1CAM Reverses Cisplatin Resistance of Triple Negative Breast Cancer Cells by Blocking AKT Signaling Pathway

Authors: Lu-Yao Zhang, Zhi-Xin Shen, Lu Guo

Journal: Cancer Invest

PubMed ID: 35040385

Doi: 10.1080/07357907.2021.2016801

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Formation of β-Strand Oligomers of Antimicrobial Peptide Magainin 2 Contributes to Disruption of Phospholipid Membrane

Authors: Munehiro Kumashiro, Ryoga Tsuji, Shoma Suenaga, Koichi Matsuo

Journal: Membranes (Basel)

PubMed ID: 35207051

Doi: 10.3390/membranes12020131

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Circ_HECTD1 regulates cerebral ischemia injury via mechanisms involving the regulation of let-7c-5p/ROCK1 axis

Authors: Qian Guo, Tingting Guo, Yuanyuan Sun, Tianrong Chen

Journal: Neuroreport

PubMed ID: 34874325

Doi: 10.1097/WNR.0000000000001743

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Hempseed () Peptides WVSPLAGRT and IGFLIIWV Exert Anti-inflammatory Activity in the LPS-Stimulated Human Hepatic Cell Line

Authors: Ivan Cruz-Chamorro, Guillermo Santos-Sánchez, Carlotta Bollati, Martina Bartolomei, Jianqiang Li, Anna Arnoldi, Carmen Lammi

Journal: J Agric Food Chem

PubMed ID: 35007086

Doi: 10.1021/acs.jafc.1c07520

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Bio-nanocapsules for oriented immobilization of DNA aptamers on aptasensors

Authors: Masumi Iijima, Yuki Yamada, Hideo Nakano, Tsutomu Nakayama, Shun'ichi Kuroda

Journal: Analyst

PubMed ID: 35023508

Doi: 10.1039/d1an02278d

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The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential

Authors: Lu Wang, Xi Wang, Xiying Lv, Qiushuo Jin, Hongcai Shang, Chih-Chen Wang, Lei Wang

Journal: Redox Biol

PubMed ID: 35077997

Doi: 10.1016/j.redox.2022.102244

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Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence

Authors: Stefano Perni, Kurt Beam

Journal: J Gen Physiol

PubMed ID: 35089322

Doi: 10.1085/jgp.202113024

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Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles

Authors: Yueyue Duan, Liyan Cao, Cong Yuan, Xuepeng Suo, Xiangyu Kong, Yulong Gao, Xiangtong Li, Haixue Zheng, Xiaomei Wang, Qi Wang

Journal: MBio

PubMed ID: 35038897

Doi: 10.1128/mbio.03287-21

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Conditional Alternative Protein Splicing Promoted by Inteins from

Authors: Vaishnavi R Yalala, Abigeal K Lynch, Kenneth V Mills

Journal: Biochemistry

PubMed ID: 35073064

Doi: 10.1021/acs.biochem.1c00788

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Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity

Authors: Ming Xia, Md Rejaul Hoq, Pengwei Huang, Wen Jiang, Xi Jiang, Ming Tan

Journal: Nano Res

PubMed ID: 35106126

Doi: 10.1007/s12274-021-4011-x

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Trichodysplasia spinulosa polyomavirus small T antigen synergistically modulates S6 protein translation and DNA damage response pathways to shape host cell environment

Authors: Deepika Narayanan, Danyal Tahseen, Brooke R Bartley, Stephen A Moore, Rebecca Simonette, Peter L Rady, Stephen K Tyring

Journal: Virus Genes

PubMed ID: 35000075

Doi: 10.1007/s11262-021-01880-7

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Bioengineered pseudovirus nanoparticles displaying the HA1 antigens of influenza viruses for enhanced immunogenicity

Authors: Ming Xia, Md Rejaul Hoq, Pengwei Huang, Wen Jiang, Xi Jiang, Ming Tan

Journal: Nano Res

PubMed ID: 35106126

Doi: 10.1007/s12274-021-4011-x

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HOTAIR Induces the Downregulation of miR-200 Family Members in Gastric Cancer Cell Lines

Authors: Fatemeh Bossaghzadeh, Mohammadreza Hajjari, Abdolkarim Sheikhi, Iman Salahshourifar, Shiva Irani

Journal: Iran Biomed J

PubMed ID: 34923813

Doi: 10.52547/ibj.26.1.77

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Formation of Calprotectin-Derived Peptides in the Airways of Children with Cystic Fibrosis

Authors: Teagan S Edwards, Nina Dickerhof, Nicholas J Magon, Louise N Paton, Peter D Sly, Anthony J Kettle

Journal: J Immunol

PubMed ID: 35046105

Doi: 10.4049/jimmunol.2001017

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Genome-Wide Identification and Expression Profile Analysis of the SnRK2 Gene Family in Nicotiana tabacum

Authors: Jinghao Li, Jiangyu Song, Changjun Li, Juntao Ma, Jiawang Liu, Xiaowei Zhu, Jingchao Li, Fan He, Chao Yang

Journal: Biochem Genet

PubMed ID: 35048221

Doi: 10.1007/s10528-021-10170-8

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Development of an enzymatic method for the evaluation of protein deposition on contact lenses

Authors: Simin Masoudi, Mark Willcox

Journal: Biofouling

PubMed ID: 35016572

Doi: 10.1080/08927014.2021.2019225

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A Micrarchaeon isolate is covered by a proteinaceous S-Layer

Authors: Sabrina Gfrerer, Dennis Winkler, Julia Novion Ducassou, Yohann Couté, Reinhard Rachel, Johannes Gescher

Journal: Appl Environ Microbiol

PubMed ID: 35020453

Doi: 10.1128/AEM.01553-21

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A Micrarchaeon isolate is covered by a proteinaceous S-Layer

Authors: Sabrina Gfrerer, Dennis Winkler, Julia Novion Ducassou, Yohann Couté, Reinhard Rachel, Johannes Gescher

Journal: Appl Environ Microbiol

PubMed ID: 35020453

Doi: 10.1128/AEM.01553-21

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The Novel microRNA Rno-miR-686-3p Is Associated with the Ischaemic Penumbra

Authors: Wei Wang, Jin-Pin Li, Jing-Li Liu

Journal: Eur Neurol

PubMed ID: 35100587

Doi: 10.1159/000521491

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Survey of SARS-CoV-2 in dogs and cats in high-risk areas during the second wave of COVID-19 outbreak, Thailand

Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Aphinya Hangsawek, Suchart Waenkaew, Anek Mungaomklang, Ratanaporn Tangwangvivat, Alongkorn Amonsin

Journal: Zoonoses Public Health

PubMed ID: 34981900

Doi: 10.1111/zph.12907

Safety and Immunogenicity of the Third Booster Dose with Inactivated, Viral Vector, and mRNA COVID-19 Vaccines in Fully Immunized Healthy Adults with Inactivated Vaccine

Authors: Sitthichai Kanokudom, Suvichada Assawakosri, Nungruthai Suntronwong, Chompoonut Auphimai, Pornjarim Nilyanimit, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Ritthideach Yorsaeng, Donchida Srimuan, Thaksaporn Thatsanatorn, Sirapa Klinfueng, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Sittisak Honsawek, Yong Poovorawan

Journal: Vaccines (Basel)

PubMed ID: 35062747

Doi: 10.3390/vaccines10010086

Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway

Authors: Veronica Mutti, Federica Bono, Zaira Tomasoni, Leonardo Bontempi, Adele Guglielmi, Silvia Bolognin, Jens C Schwamborn, Cristina Missale, Chiara Fiorentini

Journal: Mol Neurobiol

PubMed ID: 35044626

Doi: 10.1007/s12035-022-02748-z

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In vivo HSC gene therapy for SARS-CoV2 infection using a decoy receptor

Authors: Hongjie Wang, Chang Li, Adebimpe Obadan, Hannah Frizzell, Tien-Ying Hsiang, Sucheol Gil, Audrey Germond, Connie Fountain, Audrey Baldessari, Steve Roffler, Hans-Peter Kiem, Deborah Fuller, Andre Lieber

Journal: Hum Gene Ther

PubMed ID: 35057635

Doi: 10.1089/hum.2021.295

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Development and Clinical Validation of a Potential Penside Colorimetric Loop-Mediated Isothermal Amplification Assay of Porcine Circovirus Type 3

Authors: Jie Zhang, Miaomiao Li, Yunwen Ou, Danian Chen, Yaozhong Ding, Weibing Zhang, Yanjun Li, Qian Hou, Xiaoyun Li, Luoyi Zhou, Katarzyna Podgorska, Alexei D Zaberezhny, Anna Szczotka-Bochniarz, Yongsheng Liu, Yang Wang

Journal: Front Microbiol

PubMed ID: 35095787

Doi: 10.3389/fmicb.2021.758064

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Optimization of loop-mediated isothermal amplification (LAMP) assay for robust visualization in SARS-CoV-2 and emerging variants diagnosis

Authors: Zhen Luo, Chunhong Ye, Heng Xiao, Jialing Yin, Yicong Liang, Zhihui Ruan, Danju Luo, Daolong Gao, Qiuping Tan, Yongkui Li, Qiwei Zhang, Weiyong Liu, Jianguo Wu

Journal: Chem Eng Sci

PubMed ID: 35043022

Doi: 10.1016/j.ces.2022.117430

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miR-505 inhibits replication of Borna disease virus 1 via inhibition of HMGB1-mediated autophagy

Authors: Yujie Guo, Xiaoyan Xu, Tian Tang, Lin Sun, Xiong Zhang, Xia Shen, Dan Li, Lixin Wang, Libo Zhao, Peng Xie

Journal: J Gen Virol

PubMed ID: 35060474

Doi: 10.1099/jgv.0.001713

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Prognostic significance of a complement factor H autoantibody in early stage NSCLC

Authors: Elizabeth B Gottlin, Michael J Campa, Rikesh Gandhi, Ryan T Bushey, James E Herndon, Edward F Patz

Journal: Cancer Biomark

PubMed ID: 35068447

Doi: 10.3233/CBM-210355

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An AAV vaccine targeting the RBD of the SARS-CoV-2 S protein induces effective neutralizing antibody titers in mice and canines

Authors: Fei Liu, Canbin Feng, Shiqi Xu, Qiang Wu, Jian Tang, Yan Chen, Ruisheng Xu, Fuliang Chen, Ni Gao, Zhengzheng Xu, Shihui Gu, Yang Lan, Haibo Zhou, Xinde Hu, Xiaojing Wang

Journal: Vaccine

PubMed ID: 35094871

Doi: 10.1016/j.vaccine.2022.01.030

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ADAM17 regulates the proliferation and extracellular matrix of keloid fibroblasts by mediating the EGFR/ERK signaling pathway

Authors: Xin Le, You-Fen Fan

Journal: J Plast Surg Hand Surg

PubMed ID: 34978504

Doi: 10.1080/2000656X.2021.2017944

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Downregulation of estrogen receptor-α36 expression attenuates metastasis of hepatocellular carcinoma cells

Authors: Ruobing Wang, Jiaming Chen, Haiyan Yu, Zhixuan Wei, Min Ma, Xueyan Ye, Weiqi Wu, Hongfei Chen, Zhengqi Fu

Journal: Environ Toxicol

PubMed ID: 35044086

Doi: 10.1002/tox.23469

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Waning antibody levels after COVID-19 vaccination with mRNA Comirnaty and inactivated CoronaVac vaccines in blood donors, Hong Kong, April 2020 to October 2021

Authors: Shirley Ll Kwok, Samuel Ms Cheng, Jennifer Ns Leung, Kathy Leung, Cheuk-Kwong Lee, Js Malik Peiris, Joseph T Wu

Journal: Euro Surveill

PubMed ID: 35027105

Doi: 10.2807/1560-7917.ES.2022.27.2.2101197

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Self-assembling ferritin nanoparticles coupled with linear sequences from canine distemper virus haemagglutinin protein elicit robust immune responses

Authors: Bo Wang, Shuang Li, Yongbo Qiao, Yu Fu, Jiaojiao Nie, Shun Jiang, Xin Yao, Yi Pan, Linye Zhao, Congmei Wu, Yuhua Shi, Yuhe Yin, Yaming Shan

Journal: J Nanobiotechnology

PubMed ID: 35012571

Doi: 10.1186/s12951-021-01229-0

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K-edge anomalous SAXS for protein solution structure modeling

Authors: Karman Virk, Kento Yonezawa, Komal Choukate, Lucky Singh, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35102886

Doi: 10.1107/S205979832101247X

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Genome-wide identification and expression pattern analysis of the TCP transcription factor family in

Authors: Li Yu, Qiangwen Chen, Jiarui Zheng, Feng Xu, Jiabao Ye, Weiwei Zhang, Yongling Liao, Xiaoyan Yang

Journal: Plant Signal Behav

PubMed ID: 35068346

Doi: 10.1080/15592324.2021.1994248

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Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells

Authors: Fei Liao, Jing Zhang, Yangyang Hu, Alireza Hassani Najafabadi, James J Moon, Max S Wicha, Bashir Kaspo, Joel Whitfield, Alfred E Chang, Qiao Li

Journal: Cancer Immunol Immunother

PubMed ID: 35098344

Doi: 10.1007/s00262-021-03129-6

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miR-223 in exosomes from bone marrow mesenchymal stem cells ameliorates rheumatoid arthritis via downregulation of NLRP3 expression in macrophages

Authors: Ying Huang, Daomin Lu, Wukai Ma, Jun Liu, Qiaoyi Ning, Fang Tang, Long Li

Journal: Mol Immunol

PubMed ID: 35042119

Doi: 10.1016/j.molimm.2022.01.002

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A Pig-a conditional knock-out mice model mediated by Vav-iCre: stable GPI-deficient and mild hemolysis

Authors: Yingying Chen, Hui Liu, Lijie Zeng, Liyan Li, Dan Lu, Zhaoyun Liu, Rong Fu

Journal: Exp Hematol Oncol

PubMed ID: 35033195

Doi: 10.1186/s40164-022-00254-5

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A Pig-a conditional knock-out mice model mediated by Vav-iCre: stable GPI-deficient and mild hemolysis

Authors: Yingying Chen, Hui Liu, Lijie Zeng, Liyan Li, Dan Lu, Zhaoyun Liu, Rong Fu

Journal: Exp Hematol Oncol

PubMed ID: 35033195

Doi: 10.1186/s40164-022-00254-5

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Bioinformatics based discovery of new keratinases in protease family M36

Authors: Jingwen Qiu, Kristian Barrett, Casper Wilkens, Anne S Meyer

Journal: N Biotechnol

PubMed ID: 35032710

Doi: 10.1016/j.nbt.2022.01.004

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Clinical Potential of lncRNA PPP1R26-AS1 in Breast Cancer and Its Contribution to Cancer Progression

Authors: Shuping Zhou, Shaoli Zhang, Hui Zhang, Junxia Ma, Huangzhen Dai, Lili Qu, Meixiang Zhou

Journal: Mol Biotechnol

PubMed ID: 35064892

Doi: 10.1007/s12033-022-00452-w

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Antibody Responses after SARS-CoV-2 Vaccination in Patients with Liver Diseases

Authors: Athanasios-Dimitrios Bakasis, Kleopatra Bitzogli, Dimitrios Mouziouras, Abraham Pouliakis, Maria Roumpoutsou, Andreas V Goules, Theodoros Androutsakos

Journal: Viruses

PubMed ID: 35215801

Doi: 10.3390/v14020207

Antibody Responses after SARS-CoV-2 Vaccination in Patients with Liver Diseases

Authors: Athanasios-Dimitrios Bakasis, Kleopatra Bitzogli, Dimitrios Mouziouras, Abraham Pouliakis, Maria Roumpoutsou, Andreas V Goules, Theodoros Androutsakos

Journal: Viruses

PubMed ID: 35215801

Doi: 10.3390/v14020207

Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome

Authors: Juan Manuel Orozco Rodriguez, Ewa Krupinska, Hanna Wacklin-Knecht, Wolfgang Knecht

Journal: Nucleosides Nucleotides Nucleic Acids

PubMed ID: 35094635

Doi: 10.1080/15257770.2021.2023749

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Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI9 norovirus, as revealed by structural analysis

Authors: Tomomi Kimura-Someya, Miyuki Kato-Murayama, Kazushige Katsura, Naoki Sakai, Kazutaka Murayama, Kazuharu Hanada, Mikako Shirouzu, Yuichi Someya

Journal: FEBS Open Bio

PubMed ID: 35038379

Doi: 10.1002/2211-5463.13370

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Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants

Authors: Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran

Journal: Viruses

PubMed ID: 35215823

Doi: 10.3390/v14020230

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Preparation of Edible Films with and Lactobionic Acid Produced by Sweet Whey Fermentation

Authors: Sara Sáez-Orviz, Ismael Marcet, Manuel Rendueles, Mario Díaz

Journal: Membranes (Basel)

PubMed ID: 35207037

Doi: 10.3390/membranes12020115

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Antibody response following SARS-CoV-2 vaccination among patients with type 2 diabetes mellitus: A systematic review

Authors: Nanny Natalia M Soetedjo, Maria Riastuti Iryaningrum, Sherly Lawrensia, Hikmat Permana

Journal: Diabetes Metab Syndr

PubMed ID: 35104750

Doi: 10.1016/j.dsx.2022.102406

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Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses primed by an injected vaccine

Authors: Jacob Pitcovski, Nady Gruzdev, Anna Abzach, Chen Katz, Ran Ben-Adiva, Michal Brand-Shwartz, Itamar Yadid, Einav Ratzon-Ashkenazi, Ken Emquies, Hadasa Israeli, Hadar Haviv, Irena Rapoport, Itai Bloch, Roy Shadmon, Zohar Eitan, Dalia Eliahu, Talia Hilel, Morris Laster, Sigal Kremer-Tal, Tamara Byk-Tennenbaum, Ehud Shahar

Journal: Vaccine

PubMed ID: 35078662

Doi: 10.1016/j.vaccine.2022.01.025

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LbCas12a-D156R Efficiently Edits Effector Binding Elements to Generate Canker-Resistant Citrus Plants

Authors: Hongge Jia, Yuanchun Wang, Hang Su, Xiaoen Huang, Nian Wang

Journal: Cells

PubMed ID: 35159125

Doi: 10.3390/cells11030315

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Neutralizing Activity and SARS-CoV-2 Vaccine mRNA Persistence in Serum and Breastmilk After BNT162b2 Vaccination in Lactating Women

Authors: Kee Thai Yeo, Wan Ni Chia, Chee Wah Tan, Chengsi Ong, Joo Guan Yeo, Jinyan Zhang, Su Li Poh, Amanda Jin Mei Lim, Kirsten Hui Zhi Sim, Nursyuhadah Sutamam, Camillus Jian Hui Chua, Salvatore Albani, Lin-Fa Wang, Mei Chien Chua

Journal: Front Immunol

PubMed ID: 35087517

Doi: 10.3389/fimmu.2021.783975

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Neutralizing Activity and SARS-CoV-2 Vaccine mRNA Persistence in Serum and Breastmilk After BNT162b2 Vaccination in Lactating Women

Journal: Front Immunol

PubMed ID: 35087517

Doi: 10.3389/fimmu.2021.783975

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The Linker Region Promotes Activity and Binding Efficiency of Modular LPMO towards Polymeric Substrate

Authors: Aishwarya Srivastava, Pragya Nagar, Sumit Rathore, Nidhi Adlakha

Journal: Microbiol Spectr

PubMed ID: 35080440

Doi: 10.1128/spectrum.02697-21

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CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA

Authors: Simin Chen, Zhaoyu Zhang, Baoxin Zhang, Qing Huang, Yi Liu, Yi Qiu, Xinmiao Long, Minghua Wu, Zuping Zhang

Journal: Int J Biol Sci

PubMed ID: 35002529

Doi: 10.7150/ijbs.66114

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Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice

Authors: Yi Zhang, Mufan Ji, Zhenyang Gu, Wenlong Pei, Jun Zhu, Qian Wu, Lei Li, Zhan Zhang

Journal: Toxicology

PubMed ID: 34979169

Doi: 10.1016/j.tox.2021.153088

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Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin

Authors: Favian A Liu, Negar Ardabili, Izaiah Brown, Harmain Rafi, Clarice Cook, Rodanthi Nikopoulou, Arianna Lopez, Shouzhong Zou, Matthew R Hartings, Alexander G Zestos

Journal: J Electrochem Soc

PubMed ID: 35185166

Doi: 10.1149/1945-7111/ac4aae

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Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates

Authors: Stéphane Pillet, Prabhu S Arunachalam, Guadalupe Andreani, Nadia Golden, Jane Fontenot, Pyone Pyone Aye, Katharina Röltgen, Gabrielle Lehmicke, Philipe Gobeil, Charlotte Dubé, Sonia Trépanier, Nathalie Charland, Marc-André D'Aoust, Kasi Russell-Lodrigue, Christopher Monjure, Robert V Blair, Scott D Boyd, Rudolf P Bohm, Jay Rappaport, François Villinger, Nathalie Landry, Bali Pulendran, Brian J Ward

Journal: Cell Mol Immunol

PubMed ID: 34983950

Doi: 10.1038/s41423-021-00809-2

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Evolutionary Origin of the Carotenoid Cleavage Oxygenase Family in Plants and Expression of Pepper Genes in Response to Abiotic Stresses

Authors: Yixiu Yao, Li Jia, Yuan Cheng, Meiying Ruan, Qingjing Ye, Rongqing Wang, Zhuping Yao, Guozhi Zhou, Jia Liu, Jiahong Yu, Peng Zhang, Yuhe Yin, Weiping Diao, Hongjian Wan

Journal: Front Plant Sci

PubMed ID: 35126418

Doi: 10.3389/fpls.2021.792832

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Improved yield, stability, and cleavage reaction of a novel tobacco etch virus protease mutant

Authors: Sergio Enríquez-Flores, José Ignacio De la Mora-De la Mora, Luis Antonio Flores-López, Nallely Cabrera, Cynthia Fernández-Lainez, Gloria Hernández-Alcántara, Carlos Enrique Guerrero-Beltrán, Gabriel López-Velázquez, Itzhel García-Torres

Journal: Appl Microbiol Biotechnol

PubMed ID: 35092453

Doi: 10.1007/s00253-022-11786-5

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N-glycolylneuraminic acid binding of avian and equine H7 influenza A viruses

Authors: Cindy M Spruit, Xueyong Zhu, Ilhan Tomris, María Ríos Carrasco, Alvin X Han, Frederik Broszeit, Roosmarijn van der Woude, Kim M Bouwman, Michel M T Luu, Keita Matsuno, Yoshihiro Sakoda, Colin A Russell, Ian A Wilson, Geert-Jan Boons, Robert P de Vries

Journal: J Virol

PubMed ID: 35044215

Doi: 10.1128/jvi.02120-21

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pVHL-mediated SMAD3 degradation suppresses TGF-β signaling

Authors: Jun Zhou , Yasamin Dabiri , Rodrigo A Gama-Brambila, Shahrouz Ghafoory , Mukaddes Altinbay , Arianeb Mehrabi , Mohammad Golriz , Biljana Blagojevic , Stefanie Reuter , Kang Han , Anna Seidel , Ivan Đikić , Stefan Wölfl , Xinlai Cheng

Journal: J Cell Biol

PubMed ID: 34860252

Doi: 10.1083/jcb.202012097

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Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay

Authors: Yusen Xiang, Guanglei Zhai, Yaozong Li, Mengge Wang, Xixiang Chen, Ruyu Wang, Hang Xie, Weidong Zhang, Guangbo Ge, Qian Zhang, Yechun Xu, Amedeo Caflisch, Jianrong Xu, Hongzhuan Chen, Lili Chen

Journal: Int J Biol Macromol

PubMed ID: 36521705

Doi: 10.1016/j.ijbiomac.2022.12.057

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