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Efficacy and Safety of Heterologous Booster Vaccination after Ad5-nCoV (CanSino Biologics) Vaccine: A Preliminary Descriptive Study
Authors: José Francisco Muñoz-Valle, Gabriela Athziri Sánchez-Zuno, Mónica Guadalupe Matuz-Flores, Cristian Oswaldo Hernández-Ramírez, Saúl Alberto Díaz-Pérez, Christian Johana Baños-Hernández, Francisco Javier Turrubiates-Hernández, Alejandra Natali Vega-Magaña, Jorge Hernández-Bello
Journal: Vaccines (Basel)
PubMed ID: 35335032
Doi: 10.3390/vaccines10030400
Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With Pathogenic Variants
Authors: Niklas Schwarz, Simone Seiffert, Manuela Pendziwiat, Annika Verena Rademacher, Tobias Brünger, Ulrike B S Hedrich, Paul B Augustijn, Hartmut Baier, Allan Bayat, Francesca Bisulli, Russell J Buono, Ben Zeev Bruria, Michael G Doyle, Renzo Guerrini, Gali Heimer, Michele Iacomino, Hugh Kearney, Karl Martin Klein, Ioanna Kousiappa, Wolfram S Kunz, Holger Lerche, Laura Licchetta, Ebba Lohmann, Raffaella Minardi, Marie McDonald, Sarah Montgomery, Lejla Mulahasanovic, Renske Oegema, Barel Ortal, Savvas S Papacostas, Francesca Ragona, Tiziana Granata, Phillip S Reif, Felix Rosenow, Annick Rothschild, Paolo Scudieri, Pasquale Striano, Paolo Tinuper, George A Tanteles, Annalisa Vetro, Felix Zahnert, Ethan M Goldberg, Federico Zara, Dennis Lal, Patrick May, Hiltrud Muhle, Ingo Helbig, Yvonne Weber
Journal: Neurology
PubMed ID: 35314505
Doi: 10.1212/WNL.0000000000200660
Products & Services: Protein and Antibody Isolation   
Site-specific nanobody-oligonucleotide conjugation for super-resolution imaging
Authors: Laura Teodori, Marjan Omer, Anders Märcher, Mads K Skaanning, Veronica L Andersen, Jesper S Nielsen, Emil Oldenburg, Yuchen Lin, Kurt V Gothelf, Jørgen Kjems
Journal: J Biol Methods
PubMed ID: 35510035
Doi: 10.14440/jbm.2022.381
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Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity
Authors: Lauren B Rodda, Peter A Morawski, Kurt B Pruner, Mitchell L Fahning, Christian A Howard, Nicholas Franko, Jennifer Logue, Julie Eggenberger, Caleb Stokes, Inah Golez, Malika Hale, Michael Gale, Helen Y Chu, Daniel J Campbell, Marion Pepper
Journal: Cell
PubMed ID: 35413241
Doi: 10.1016/j.cell.2022.03.018
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Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis
Authors: Yiqi Yang , Yixuan Lin , Minqi Wang , Kai Yuan , Qishan Wang , Pei Mu , Jingke Du , Zhifeng Yu , Shengbing Yang , Kai Huang , Yugang Wang , Hanjun Li , Tingting Tang
Journal: Bone Res
PubMed ID: 35260560
Doi: doi.org/10.1038/s41413-022-00198-w
Products & Services: Protein Electrophoresis and Western   
DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas
Authors: Xizhou Zhu, Alfredo Perales-Puchalt, Krzysztof Wojtak, Ziyang Xu, Kun Yun, Pratik S Bhojnagarwala , Devivasha Bordoloi , Daniel H Park, Kevin Liaw, Mamadou A Bah, Paul M Lieberman , Ebony N Gary , Ami Patel , David B Weiner
Journal: Mol Ther Oncolytics
PubMed ID: 35071745
Doi: 10.1016/j.omto.2021.12.017
Products & Services: Plasmid DNA Preparation   Peptide Synthesis   
RNF115 Inhibits the Post-ER Trafficking ofTLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination ofRAB1A and RAB13
Authors: Zhi-Dong Zhang , Hong-Xu Li , Hu Gan , Zhen Tang , Yu-Yao Guo , Shu-Qi Yao , Tianzi Liuyu , Bo Zhong , Dandan Lin
Journal: Adv Sci (Weinh)
PubMed ID: 35343654
Doi: doi.org/10.1002/advs.202105391
Products & Services: Peptide Synthesis   
SARS-CoV-2 variant B.1.1.7 caused HLA-A2 CD8 T cell epitope mutations for impaired cellular immune response.
Authors: Chanchan Xiao, Lipeng Mao , Zhigang Wang , Lijuan Gao , Guodong Zhu , Jun Su , Xiongfei Chen , Jun Yuan , Yutian Hu, Zhinan Yin, Jun Xie , Weiqing Ji , Haitao Niu , Feng Gao, Oscar Junhong Luo , Lianbo Xiao , Pengcheng Wang , Guobing Chen
Journal: iScience
PubMed ID: 35194575
Doi: 10.1016/j.isci.2022.103934
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TFPIisacoloniccryptreceptorforTcdBfromhypervirulentclade2C.difficile
Authors: Jianhua Luo , Qi Yang , Xiaofeng Zhang , Yuanyuan Zhang , Li Wan , Xiechao Zhan , Yao Zhou , Liuqing He , Danyang Li , Dazhi Jin , Ying Zhen , Jing Huang , Yanyan Li , Liang Tao
Journal: Cell
PubMed ID: 35303428
Doi: 10.1016/j.cell.2022.02.010
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Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis
Authors: Yang Tan, Xueqing Sun, Yizhu Xu, Bingjie Tang, Shuaiqi Xu, Dong Lu, Yan Ye, Xiaomin Luo, Xu Diao, Fulong Li, Tianyi Wang, Jiayu Chen, Qiang Xu, Xingxin Wu
Journal: Nucleic Acids Res
PubMed ID: 35234905
Doi: 10.1093/nar/gkac139
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Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors
Authors: Jia Duan , Dan-Dan Shen , Tingting Zhao , Shimeng Guo , Xinheng He , Wanchao Yin , Peiyu Xu , Yujie Ji , Li-Nan Chen , Jinyu Liu , Huibing Zhang , Qiufeng Liu , Yi Shi , Xi Cheng , Hualiang Jiang , H Eric Xu , Yan Zhang , Xin Xie , Yi Jiang
Journal: Nat Commun
PubMed ID: 35292680
Doi: 10.1038/s41467-022-29072-3
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A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination
Authors: Karen Colwill, Yannick Galipeau, Matthew Stuible, Christian Gervais, Corey Arnold, Bhavisha Rathod, Kento T Abe, Jenny H Wang, Adrian Pasculescu, Mariam Maltseva, Lynda Rocheleau, Martin Pelchat, Mahya Fazel-Zarandi, Mariam Iskilova, Miriam Barrios-Rodiles, Linda Bennett, Kevin Yau, François Cholette, Christine Mesa, Angel X Li, Aimee Paterson, Michelle A Hladunewich, Pamela J Goodwin, Jeffrey L Wrana, Steven J Drews, Samira Mubareka, Allison J McGeer, John Kim, Marc-André Langlois, Anne-Claude Gingras, Yves Durocher
Journal: Clin Transl Immunology
PubMed ID: 35356067
Doi: 10.1002/cti2.1380
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Degenerate sequence-based CRISPR diagnostic for Crimean-Congo hemorrhagic fever virus
Authors: Hongzhao Li, Alexander Bello, Greg Smith, Dominic M S Kielich, James E Strong, Bradley S Pickering
Journal: PLoS Negl Trop Dis
PubMed ID: 35271569
Doi: 10.1371/journal.pntd.0010285
Products & Services: PCR Cloning and Subcloning   
Complement C3a Enhances the Phagocytic Activity of B Cells Through C3aR in a Fish
Authors: Zi-You Ma, Jia-Xin Liang, Wen-Shuo Li, Yuan Sun, Chang-Song Wu, Ya-Zhen Hu, Jun Li, Yong-An Zhang, Xu-Jie Zhang
Journal: Front Immunol
PubMed ID: 35386704
Doi: 10.3389/fimmu.2022.873982
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Therapeutic Effect of Melittin-dKLA Targeting Tumor-Associated Macrophages in Melanoma
Authors: Ik-Hwan Han, Chanmi Jeong, Juwon Yang, Seung-Hyeok Park, Deok-Sang Hwang, Hyunsu Bae
Journal: Int J Mol Sci
PubMed ID: 35328518
Doi: 10.3390/ijms23063094
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Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
Authors: Kim van Kuijk, Jasper A F Demandt, Javier Perales-Patón, Thomas L Theelen, Christoph Kuppe, Elke Marsch, Jenny de Bruijn, Han Jin, Marion J Gijbels, Ljubica Matic, Barend M E Mees, Chris P M Reutelingsperger, Ulf Hedin, Erik A L Biessen, Peter Carmeliet, Andrew H Baker, Rafael K Kramann, Leon J Schurgers, Julio Saez-Rodriguez, Judith C Sluimer
Journal: Cardiovasc Res
PubMed ID: 33913468
Doi: 10.1093/cvr/cvab152
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Injectable Slow-Release Hydrogel Formulation of a Plant Virus-Based COVID-19 Vaccine Candidate
Authors: Christian Isalomboto Nkanga, Oscar A Ortega-Rivera, Matthew D Shin, Miguel A Moreno-Gonzalez, Nicole F Steinmetz
Journal: Biomacromolecules
PubMed ID: 35344365
Doi: 10.1021/acs.biomac.2c00112
Products & Services: Recombinant Proteins   
Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a
Authors: Shuhan Lu, Xiaohan Tong, Yang Han, Kun Zhang, Yizhou Zhang, Qiubing Chen, Junyi Duan, Xinlin Lei, Muhan Huang, Yang Qiu, Ding-Yu Zhang, Xi Zhou, Ying Zhang, Hao Yin
Journal: Nat Biomed Eng
PubMed ID: 35314803
Doi: 10.1038/s41551-022-00861-x
Products & Services: Gene Synthesis   
Evaluation of the Humoral Immune Response of a Heterologous Vaccination between BBIBP-CorV and BNT162b2 with a Temporal Separation of 7 Months, in Peruvian Healthcare Workers with and without a History of SARS-CoV-2 Infection
Authors: Miguel Hueda-Zavaleta, Juan C Gómez de la Torre, José Alonso Cáceres-Del Aguila, Cecilia Muro-Rojo, Nathalia De La Cruz-Escurra, Daniella Arenas Siles, Diana Minchón-Vizconde, Cesar Copaja-Corzo, Fabrizzio Bardales-Silva, Vicente A Benites-Zapata, Alfonso J Rodriguez-Morales
Journal: Vaccines (Basel)
PubMed ID: 35455251
Doi: 10.3390/vaccines10040502
Phage Therapy Potentiates Second-Line Antibiotic Treatment against Pneumonic Plague
Authors: Yaron Vagima, David Gur, Moshe Aftalion, Sarit Moses, Yinon Levy, Arik Makovitzki, Tzvi Holtzman, Ziv Oren, Yaniv Segula, Ella Fatelevich, Avital Tidhar, Ayelet Zauberman, Shahar Rotem, Emanuelle Mamroud, Ida Steinberger-Levy
Journal: Viruses
PubMed ID: 35458417
Doi: 10.3390/v14040688
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Structure-based design and construction of a synthetic phage display nanobody library
Authors: Ernesto Moreno, Mario S Valdés-Tresanco, Andrea Molina-Zapata, Oliberto Sánchez-Ramos
Journal: BMC Res Notes
PubMed ID: 35351202
Doi: 10.1186/s13104-022-06001-7
Products & Services: Gene Synthesis   
Highly Specific Monoclonal Antibody Targeting the Botulinum Neurotoxin Type E Exposed SNAP-25 Neoepitope
Authors: Adva Mechaly, Eran Diamant, Ron Alcalay, Alon Ben David, Eyal Dor, Amram Torgeman, Ada Barnea, Meni Girshengorn, Lilach Levin, Eyal Epstein, Ariel Tennenhouse, Sarel J Fleishman, Ran Zichel, Ohad Mazor
Journal: Antibodies (Basel)
PubMed ID: 35323195
Doi: 10.3390/antib11010021
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COVID-19 Breakthrough Infection after Inactivated Vaccine Induced Robust Antibody Responses and Cross-Neutralization of SARS-CoV-2 Variants, but Less Immunity against Omicron
Authors: Nungruthai Suntronwong, Ritthideach Yorsaeng, Jiratchaya Puenpa, Chompoonut Auphimai, Thanunrat Thongmee, Preeyaporn Vichaiwattana, Sitthichai Kanokudom, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Suvichada Assawakosri, Pornjarim Nilyanimit, Sirapa Klinfueng, Lakkhana Wongsrisang, Donchida Srimuan, Thaksaporn Thatsanatorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Yong Poovorawan
Journal: Vaccines (Basel)
PubMed ID: 35335023
Doi: 10.3390/vaccines10030391
A novel series of putative Brugia malayi histone demethylase inhibitors as potential anti-filarial drugs
Authors: Tamara Kreiss, Tyler Eck, Brittany Hart, Sreedhar Tummalapalli, David Rotella, John Siekierka
Journal: PLoS Negl Trop Dis
PubMed ID: 35294431
Doi: 10.1371/journal.pntd.0010216
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Performance of Chimeric Antigens in Serological Screening for Chagas Disease in Blood Banks
Authors: Emily Ferreira Dos Santos, Ângelo Antônio Oliveira Silva, Natália Erdens Maron Freitas, Leonardo Maia Leony, Ramona Tavares Daltro, Carlos Antônio de Souza Teles Santos, Maria da Conceição Chagas de Almeida, Fernando Luiz Vieira de Araújo, Paola Alejandra Fiorani Celedon, Marco Aurélio Krieger, Nilson Ivo Tonin Zanchin, Mitermayer Galvão Dos Reis, Fred Luciano Neves Santos
Journal: Front Med (Lausanne)
PubMed ID: 35330587
Doi: 10.3389/fmed.2022.852864
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MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity
Authors: Thilini S Munasinghe, Megan R Edwards, Sofiya Tsimbalyuk, Olivia A Vogel, Kate M Smith, Murray Stewart, Justin K Foster, Loretta A Bosence, David Aragão, Justin A Roby, Christopher F Basler, Jade K Forwood
Journal: Nat Commun
PubMed ID: 35338144
Doi: 10.1038/s41467-022-28851-2
Products & Services: Bacterial Expression   
Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer
Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis
Journal: Nat Commun
PubMed ID: 35256598
Doi: 10.1038/s41467-022-28741-7
Products & Services: Catalog Peptides   
The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist
Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau
Journal: PLoS Pathog
PubMed ID: 35271688
Doi: 10.1371/journal.ppat.1010355
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Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections
Authors: Melissa C Remmel, Sabrina M Coyle, Mark W Eshoo, Timothy E Sweeney, David C Rawling
Journal: Clin Chem
PubMed ID: 35134876
Doi: 10.1093/clinchem/hvab275
Products & Services: Mammalian Expression   
Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization
Authors: Edward A Partlow, Kevin S Cannon, Gunther Hollopeter, Richard W Baker
Journal: Nat Struct Mol Biol
PubMed ID: 35347313
Doi: 10.1038/s41594-022-00749-z
Products & Services: Peptide Synthesis   
Zymomonas mobilis ZM4 Utilizes an NADP-Dependent Acetaldehyde Dehydrogenase To Produce Acetate
Authors: Magdalena M Felczak, Michaela A TerAvest
Journal: J Bacteriol
PubMed ID: 35258321
Doi: 10.1128/jb.00563-21
Products & Services: Catalog Antibodies   
A simple reverse genetics method to generate recombinant coronaviruses
Authors: Julien Mélade, Géraldine Piorkowski, Franck Touret, Toscane Fourié, Jean-Sélim Driouich, Maxime Cochin, Hawa Sophia Bouzidi, Bruno Coutard, Antoine Nougairède, Xavier de Lamballerie
Journal: EMBO Rep
PubMed ID: 35239997
Doi: 10.15252/embr.202153820
Products & Services: Gene Fragments   
Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes
Authors: Baobao Chen, Mingtian Deng, Meng-Hao Pan, Shao-Chen Sun, Honglin Liu
Journal: Cell Biosci
PubMed ID: 35255956
Doi: 10.1186/s13578-022-00758-x
Products & Services: Protein and Antibody Isolation   
RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
Authors: Tal Keren-Kaplan, Amra Sarić, Saikat Ghosh, Chad D Williamson, Rui Jia, Yan Li, Juan S Bonifacino
Journal: Nat Commun
PubMed ID: 35314674
Doi: 10.1038/s41467-022-28952-y
Products & Services: Plasmid DNA Preparation   
Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression
Authors: Quan Shi, Jing Luo, Weiming Chen, Qi He, Jianwen Long, Bo Zhang
Journal: Autoimmunity
PubMed ID: 35293807
Doi: 10.1080/08916934.2022.2037127
Products & Services: Mutant Libraries   
A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants
Authors: Xing-Qi Huang, Renqiuguo Li, Jianxin Fu, Natalia Dudareva
Journal: Nat Commun
PubMed ID: 35292635
Doi: 10.1038/s41467-022-28978-2
Products & Services: Codon Optimization   
Age-dependent formation of TMEM106B amyloid filaments in human brains
Authors: Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Kathy L Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G Murzin, Michel Goedert, Sjors H W Scheres
Journal: Nature
PubMed ID: 35344985
Doi: 10.1038/s41586-022-04650-z
Products & Services: Gene Fragments   
The vaccinia-based Sementis Copenhagen Vector coronavirus disease 2019 vaccine induces broad and durable cellular and humoral immune responses
Authors: Preethi Eldi, Tamara H Cooper, Natalie A Prow, Liang Liu, Gary K Heinemann, Voueleng J Zhang, Abigail D Trinidad, Ruth Marian Guzman-Genuino, Peter Wulff, Leanne M Hobbs, Kerrilyn R Diener, John D Hayball
Journal: Immunol Cell Biol
PubMed ID: 35188985
Doi: 10.1111/imcb.12539
Products & Services: Protein and Antibody Isolation   
Alpha-hydroxytropolones are noncompetitive inhibitors of human RNase H1 that bind to the active site and modulate substrate binding
Authors: Nathan L Ponzar, Razia Tajwar, Nicola Pozzi, John E Tavis
Journal: J Biol Chem
PubMed ID: 35247386
Doi: 10.1016/j.jbc.2022.101790
Products & Services: Mutagenesis Services   
YfiB: An Outer Membrane Protein Involved in the Virulence of
Authors: Tanuka Sen, Naresh K Verma
Journal: Microorganisms
PubMed ID: 35336228
Doi: 10.3390/microorganisms10030653
Products & Services: Mutant Libraries   
Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold
Authors: Jingjing Chen, Huixin He, Aihuan Wei, Yalei Li, Gang Cheng, Hui Qin, Hanyue Zhong, Hongchun Liu, Meiyu Geng, Aijun Shen, Youhong Hu
Journal: Eur J Med Chem
PubMed ID: 35395439
Doi: 10.1016/j.ejmech.2022.114259
Products & Services: Protein Electrophoresis and Western   
Convergent epitope specificities, V gene usage and public clones elicited by primary exposure to SARS-CoV-2 variants
Authors: Noemia S Lima, Maryam Mukhamedova, Timothy S Johnston, Danielle A Wagner, Amy R Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P Black, Sijy O'Dell, Stephen D Schmidt, Damee Moon, Cynthia G Lorang, Bingchun Zhao, Man Chen, Kristin L Boswell, Jesmine Roberts-Torres, Rachel L Davis, Lowrey Peyton, Sandeep R Narpala, Sarah O'Connell, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J Ruckwardt, Amarendra Pegu, John Misasi, Nicole A Doria-Rose, Martin Gaudinski, Richard A Koup, Peter D Kwong, Adrian B McDermott, Sharon Amit, Timothy W Schacker, Itzchak Levy, John R Mascola, Nancy J Sullivan, Chaim A Schramm, Daniel C Douek
Journal: biorxiv
PubMed ID: 35378757
Doi: 10.1101/2022.03.28.486152
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Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate
Authors: Ruixue Wang, Saori Suzuki, Johnathan D Guest, Brigitte Heller, Maricar Almeda, Alexander K Andrianov, Alexander Marin, Roy A Mariuzza, Zhen-Yong Keck, Steven K H Foung, Abdul S Yunus, Brian G Pierce, Eric A Toth, Alexander Ploss, Thomas R Fuerst
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35263223
Doi: 10.1073/pnas.2112008119
Products & Services: PCR Cloning and Subcloning   
Rapid Exchange of Stably Bound Protein and DNA Cargo on a DNA Origami Receptor
Authors: James W P Brown, Rokiah G Alford, James C Walsh, Richard E Spinney, Stephanie Y Xu, Sophie Hertel, Jonathan F Berengut, Lisanne M Spenkelink, Antoine M van Oijen, Till Böcking, Richard G Morris, Lawrence K Lee
Journal: ACS Nano
PubMed ID: 35316035
Doi: 10.1021/acsnano.2c00699
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In situ solid-state NMR study of antimicrobial peptide interactions with erythrocyte membranes
Authors: Kiran Kumar, Mathew Sebastiao, Alexandre A Arnold, Steve Bourgault, Dror E Warschawski, Isabelle Marcotte
Journal: Biophys J
PubMed ID: 35278426
Doi: 10.1016/j.bpj.2022.03.009
Products & Services: Peptide Synthesis   
Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone
Authors: Ziling Ye, Yanglei Huang, Bin Shi, Zilei Xiang, Zhu Tian, Man Huang, Liangliang Wu, Zixin Deng, Kun Shen, Tiangang Liu
Journal: Metab Eng
PubMed ID: 35296429
Doi: 10.1016/j.ymben.2022.03.005
Products & Services: Molecular Biology Reagents   
Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH
Authors: Alena Stsiapanava, Chenrui Xu, Shunsuke Nishio, Ling Han, Nao Yamakawa, Marta Carroni, Kathryn Tunyasuvunakool, John Jumper, Daniele de Sanctis, Bin Wu, Luca Jovine
Journal: Nat Struct Mol Biol
PubMed ID: 35273390
Doi: 10.1038/s41594-022-00729-3
Products & Services: Mutant Libraries   
Molecular characterization, immunofluorescent localization, and expression levels of two bicarbonate anion transporters in the whitish mantle of the giant clam, Tridacna squamosa, and the implications for light-enhanced shell formation
Authors: Mel V Boo, Caryn Z Pang, Shit F Chew, Yuen K Ip
Journal: Comp Biochem Physiol A Mol Integr Physiol
PubMed ID: 35337976
Doi: 10.1016/j.cbpa.2022.111200
Products & Services: Catalog Peptides   
Dynamic observation of SARS-CoV-2 IgM, IgG, and neutralizing antibodies in the development of population immunity through COVID-19 vaccination
Authors: Ruiwei Jiang, Xiaowen Dou, Min Li, Enyun Wang, Jiwen Hu, Dan Xiong, Xiuming Zhang
Journal: J Clin Lab Anal
PubMed ID: 35235705
Doi: 10.1002/jcla.24325
Fine Mapping of the Region Identified rs7175517 as a Causal Variant Related to BMI in China and the United Kingdom Populations
Authors: Ce Lu, Hai-Jun Wang, Jie-Yun Song, Shuo Wang, Xue-Ying Li, Tao Huang, Hui Wang
Journal: Front Genet
PubMed ID: 35368675
Doi: 10.3389/fgene.2022.838685
Products & Services: Custom DNA/RNA Oligos   
Angiotensin (1-7) peptide replacement therapy with plasma transfusion in COVID-19
Authors: Hasan Onal, Nurcan Ucuncu Ergun, Bengu Arslan, Seyma Topuz, Seda Yilmaz Semerci, Osman Mutluhan Ugurel, Murat Topuzogullari, Ali Kalkan, Sengul Aydin Yoldemir, Nurettin Suner, Ali Kocatas
Journal: Transfus Apher Sci
PubMed ID: 35305923
Doi: 10.1016/j.transci.2022.103418
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Comparative Network Biology Discovers Protein Complexes That Underline Cellular Differentiation in Anabaena sp
Authors: Chen Xu, Bing Wang, Hailu Heng, Jiangmei Huang, Cuihong Wan
Journal: Mol Cell Proteomics
PubMed ID: 35288331
Doi: 10.1016/j.mcpro.2022.100224
Products & Services: Protein and Antibody Isolation   
Nup98 Is Subverted from Annulate Lamellae by Hepatitis C Virus Core Protein to Foster Viral Assembly
Authors: Bertrand Boson, Chloé Mialon, Konstanze Schichl, Solène Denolly, François-Loïc Cosset
Journal: MBio
PubMed ID: 35258330
Doi: 10.1128/mbio.02923-21
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Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses
Authors: Eva Mittler, Anna Z Wec, Janne Tynell, Pablo Guardado-Calvo, Julia Wigren-Byström, Laura C Polanco, Cecilia M O'Brien, Megan M Slough, Dafna M Abelson, Alexandra Serris, Mrunal Sakharkar, Gerard Pehau-Arnaudet, Russell R Bakken, James C Geoghegan, Rohit K Jangra, Markus Keller, Larry Zeitlin, Olli Vapalahti, Rainer G Ulrich, Zachary A Bornholdt, Clas Ahlm, Felix A Rey, John M Dye, Steven B Bradfute, Tomas Strandin, Andrew S Herbert, Mattias N E Forsell, Laura M Walker, Kartik Chandran
Journal: Sci Transl Med
PubMed ID: 35294259
Doi: 10.1126/scitranslmed.abl5399
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Structural and mechanistic basis for redox sensing by the cyanobacterial transcription regulator RexT
Authors: Bin Li, Minshik Jo, Jianxin Liu, Jiayi Tian, Robert Canfield, Jennifer Bridwell-Rabb
Journal: Commun Biol
PubMed ID: 35347217
Doi: 10.1038/s42003-022-03226-x
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Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-/Smad Pathway
Authors: Yu Wang, Sibo Sun, Kai Wang, Mingjiong Zhang, Min Li, Yumin Zan, Qiqing Huang, Shuangshuang Wu, Weihong Zhao, Wei Xu, Jianqing Wu
Journal: Mediators Inflamm
PubMed ID: 35281428
Doi: 10.1155/2022/6755407
Products & Services: Gene Synthesis   
A rationally designed synthetic antimicrobial peptide against Pseudomonas-associated corneal keratitis: Structure-function correlation
Authors: Sk Abdul Mohid, Prerana Sharma, Amani Alghalayini, Tripti Saini, Debarun Datta, Mark D P Willcox, Haydar Ali, Sreyan Raha, Achintya Singha, DongKuk Lee, Nirakar Sahoo, Charles G Cranfield, Sanhita Roy, Anirban Bhunia
Journal: Biophys Chem
PubMed ID: 35605494
Doi: 10.1016/j.bpc.2022.106802
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A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice
Authors: Xiao-Yu Teng , Ping Hu , Yangyang Chen , Yanyu Zang , Xiaolian Ye, Jingmin Ou , Guiquan Chen , Yun Stone Shi
Journal: FASEB J
PubMed ID: 35167164
Doi: 10.1096/fj.202101652R
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Impact of Modular Architecture on Activity of Glycoside Hydrolase Family 5 Subfamily 8 Mannanases
Authors: Marie Sofie Møller
Journal: Molecules
PubMed ID: 35335278
Doi: 10.3390/molecules27061915
Products & Services: Gene Synthesis   
Non-binary Encoded Nucleic Acid Barcodes Directly Readable by a Nanopore
Authors: Shuanghong Yan , Liying Wang , Yuqin Wang , Zhenyuan Cao , Shanyu Zhang , Xiaoyu Du , Pingping Fan , Panke Zhang , Hong-Yuan Chen , Shuo Huang
Journal: Angew Chem Int Ed Engl
PubMed ID: 35261129
Doi: 10.1002/anie.202116482
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Comparative genomics reveal the convergent evolution of CYP82D and CYP706X members related to flavone biosynthesis in Lamiaceae and Asteraceae
Authors: Ranran Gao, Qian Lou, Lijun Hao, Guihong Qi, Ya Tian, Xiangdong Pu, Chunnian He, Yu Wang, Wenjie Xu, Zhichao Xu, Jingyuan Song
Journal: Plant J
PubMed ID: 34907610
Doi: 10.1111/tpj.15634
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Unusual (2R,6R)-bicyclo[3.1.1]heptane ring construction in fungal a-trans-bergamotene biosynthesis
Authors: Yan-Hua Wen , Tian-Jiao Chen , Long-Yu Jiang , Li Li , Mengbo Guo , Yu Peng , Jing-Jing Chen , Fei Pei , Jin-Ling Yang , Rui-Shan Wang , Ting Gong , Ping Zhu
Journal: iScience
PubMed ID: 35345459
Doi: 10.1016/j.isci.2022.104030
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Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus
Authors: Chathura D Suraweera , Mark G Hinds , Marc Kvansakul
Journal: Viruses
PubMed ID: 35458468
Doi: 10.3390/v14040738
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Lactobacillus murinus alleviate intestinal ischemia/reperfusion injury through promoting the release of interleukin-10 from M2 macrophages via Toll-like receptor 2 signaling
Authors: Jingjuan Hu, Fan Deng, Bingcheng Zhao, Zebin Lin, Qishun Sun, Xiao Yang, Mei Wu, Shida Qiu, Yu Chen, Zhengzheng Yan, Sidan Luo, Jin Zhao, Weifeng Liu, Cai Li, Ke Xuan Liu
Journal: Microbiome
PubMed ID: 35241180
Doi: 10.1186/s40168-022-01227-w
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Targeting lipophagy in macrophages improves repair in multiple sclerosis
Authors: Mansour Haidar, Melanie Loix, Sam Vanherle, Tess Dierckx, Tim Vangansewinkel, Pascal Gervois, Esther Wolfs, Ivo Lambrichts, Jeroen F J Bogie, Jerome J A Hendriks
Journal: Autophagy
PubMed ID: 35282773
Doi: 10.1080/15548627.2022.2047343
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oligosaccharides increase serotonin in the brain and ameliorate depression promoting 5-hydroxytryptophan production in the gut microbiota
Authors: Zheng-Wei Zhang, Chun-Sheng Gao, Heng Zhang, Jian Yang, Ya-Ping Wang, Li-Bin Pan, Hang Yu, Chi-Yu He, Hai-Bin Luo, Zhen-Xiong Zhao, Xin-Bo Zhou, Yu-Li Wang, Jie Fu, Pei Han, Yu-Hui Dong, Gang Wang, Song Li, Yan Wang, Jian-Dong Jiang, Wu Zhong
Journal: Acta Pharm Sin B
PubMed ID: 35967282
Doi: 10.1016/j.apsb.2022.02.032
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Genetic ablation of the Bsx homeodomain transcription factor in zebrafish: Impact on mature pineal gland morphology and circadian behavior
Authors: Mikkel Bloss Carstensen, Adar Medvetzky, Alon Weinberger, Wolfgang Driever, Yoav Gothilf, Martin Fredensborg Rath
Journal: J Pineal Res
PubMed ID: 35249239
Doi: 10.1111/jpi.12795
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Two independent cis-acting elements are required for the guard cell-specific expression of SCAP1, which is essential for late stomatal development
Authors: Kosuke Moriwaki, Shuichi Yanagisawa, Koh Iba, Juntaro Negi
Journal: Plant J
PubMed ID: 35061307
Doi: 10.1111/tpj.15679
Products & Services: Gene Fragments   
Superior antitumor immunotherapy efficacy of kynureninase modified CAR-T cells through targeting kynurenine metabolism
Authors: Quanjun Yang, Juan Hao, Mengyi Chi, Yaxian Wang, Bo Xin, Jinglu Huang, Jin Lu, Jie Li, Xipeng Sun, Chunyan Li, Yan Huo, Jianping Zhang, Yonglong Han, Cheng Guo
Journal: Oncoimmunology
PubMed ID: 35355679
Doi: 10.1080/2162402X.2022.2055703
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Generation of Gal-enhanced bifunctional tumor vaccine
Authors: Jian He, Yu Huo, Zhikun Zhang, Yiqun Luo, Xiuli Liu, Qiaoying Chen, Pan Wu, Wei Shi, Tao Wu, Chao Tang, Huixue Wang, Lan Li, Xiyu Liu, Yong Huang, Yongxiang Zhao, Lu Gan, Bing Wang, Liping Zhong
Journal: Acta Pharm Sin B
PubMed ID: 35865091
Doi: 10.1016/j.apsb.2022.03.002
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Activation mechanism of the class D fungal GPCR dimer Ste2
Authors: Vaithish Velazhahan, Ning Ma, Nagarajan Vaidehi, Christopher G Tate
Journal: Nature
PubMed ID: 35296853
Doi: 10.1038/s41586-022-04498-3
Products & Services: Protein and Antibody Isolation   
Magnetic field-assisted aligned patterning in an alginate-silk fibroin/nanocellulose composite for guided wound healing
Authors: Keya Ganguly, Hexiu Jin, Sayan Deb Dutta, Dinesh K Patel, Tejal V Patil, Ki-Taek Lim
Journal: Carbohydr Polym
PubMed ID: 35422287
Doi: 10.1016/j.carbpol.2022.119321
Products & Services: Mammalian Expression   
Heat Shock Protein A6 Is Especially Involved in Enterovirus 71 Infection
Authors: Jiaoyan Jia, Ge Liu, Jianfeng Zhong, Ran Yan, Xun Song, Kai Zheng, Zhe Ren, Zhendan He, Qinchang Zhu
Journal: Front Microbiol
PubMed ID: 35308396
Doi: 10.3389/fmicb.2022.865644
Products & Services: Protein Electrophoresis and Western   
Pervasive translation in
Authors: Carol Smith, Jill G Canestrari, Archer J Wang, Matthew M Champion, Keith M Derbyshire, Todd A Gray, Joseph T Wade
Journal: Elife
PubMed ID: 35343439
Doi: 10.7554/eLife.73980
Products & Services: Protein and Antibody Isolation   
Neutralizing Monoclonal Antibodies Inhibit SARS-CoV-2 Infection through Blocking Membrane Fusion
Authors: Chia-Jung Li, Tai-Ling Chao, Ting-Yu Chang, Chia-Chun Hsiao, De-Chao Lu, Yi-Wei Chiang, Guan-Chun Lai, Ya-Min Tsai, Jun-Tung Fang, Siman Ieong, Jann-Tay Wang, Sui-Yuan Chang, Shih-Chung Chang
Journal: Microbiol Spectr
PubMed ID: 35293796
Doi: 10.1128/spectrum.01814-21
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Bmi-1 directly upregulates glucose transporter 1 in human gastric adenocarcinoma
Authors: Ying Guo, Guangyu Zhou, Qingjie Ma, Li Zhang, Jiwei Chen
Journal: Open Life Sci
PubMed ID: 35415241
Doi: 10.1515/biol-2022-0024
Products & Services: Gene Synthesis   
Characterization of UDP-glycosyltransferase family members reveals how major flavonoid glycoside accumulates in the roots of Scutellaria baicalensis
Authors: Tianlin Pei, Mengxiao Yan, Tian Li, Xiaoqiang Li, Yijia Yin, Mengying Cui, Yumin Fang, Jie Liu, Yu Kong, Ping Xu, Qing Zhao
Journal: BMC Genomics
PubMed ID: 35232374
Doi: 10.1186/s12864-022-08391-1
Products & Services: Gene Fragments   
HSV-2-Specific Human Female Reproductive Tract Tissue Resident Memory T Cells Recognize Diverse HSV Antigens
Authors: David M Koelle, Lichun Dong, Lichen Jing, Kerry J Laing, Jia Zhu, Lei Jin, Stacy Selke, Anna Wald, Dana Varon, Meei-Li Huang, Christine Johnston, Lawrence Corey, Christine M Posavad
Journal: Front Immunol
PubMed ID: 35432373
Doi: 10.3389/fimmu.2022.867962
Products & Services: ORF cDNA Clones/MolecularCloud   
Accurate positioning of functional residues with robotics-inspired computational protein design
Authors: Cody Krivacic, Kale Kundert, Xingjie Pan, Roland A Pache, Lin Liu, Shane O Conchúir, Jeliazko R Jeliazkov, Jeffrey J Gray, Michael C Thompson, James S Fraser, Tanja Kortemme
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35254891
Doi: 10.1073/pnas.2115480119
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VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir41/51 Inward Rectifier Potassium Channels
Authors: Samantha J McClenahan, Caitlin N Kent, Sujay V Kharade, Elena Isaeva, Jade C Williams, Changho Han, Andrew Terker, Robert Gresham, Roman M Lazarenko, Emily L Days, Ian M Romaine, Joshua A Bauer, Olivier Boutaud, Gary A Sulikowski, Raymond Harris, C David Weaver, Alexander Staruschenko, Craig W Lindsley, Jerod S Denton
Journal: Mol Pharmacol
PubMed ID: 35246480
Doi: 10.1124/molpharm.121.000464
Products & Services: Gene Synthesis   
Atomic resolution dynamics of cohesive interactions in phase-separated Nup98 FG domains
Authors: Eszter E Najbauer, Sheung Chun Ng, Christian Griesinger, Dirk Görlich, Loren B Andreas
Journal: Nat Commun
PubMed ID: 35314668
Doi: 10.1038/s41467-022-28821-8
Products & Services: Gene Fragments   
Genome sequencing of a novel Microbacterium camelliasinensis CIAB417 identified potential mannan hydrolysing enzymes
Authors: Anjali Purohit, Sudesh Kumar Yadav
Journal: Int J Biol Macromol
PubMed ID: 35331789
Doi: 10.1016/j.ijbiomac.2022.03.093
Products & Services: Gene Synthesis   
Nephronectin-integrin α8 signaling is required for proper migration of periocular neural crest cells during chick corneal development
Authors: Justin Ma, Lian Bi, James Spurlin, Peter Lwigale
Journal: Elife
PubMed ID: 35238772
Doi: 10.7554/eLife.74307
Products & Services: PCR Cloning and Subcloning   
Design of protein-binding proteins from the target structure alone
Authors: Longxing Cao, Brian Coventry, Inna Goreshnik, Buwei Huang, William Sheffler, Joon Sung Park, Kevin M Jude, Iva Marković, Rameshwar U Kadam, Koen H G Verschueren, Kenneth Verstraete, Scott Thomas Russell Walsh, Nathaniel Bennett, Ashish Phal, Aerin Yang, Lisa Kozodoy, Michelle DeWitt, Lora Picton, Lauren Miller, Eva-Maria Strauch, Nicholas D DeBouver, Allison Pires, Asim K Bera, Samer Halabiya, Bradley Hammerson, Wei Yang, Steffen Bernard, Lance Stewart, Ian A Wilson, Hannele Ruohola-Baker, Joseph Schlessinger, Sangwon Lee, Savvas N Savvides, K Christopher Garcia, David Baker
Journal: Nature
PubMed ID: 35332283
Doi: 10.1038/s41586-022-04654-9
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Characterization of SARS-CoV-2 Variants B16171 (Kappa), B16172 (Delta), and B1618 by Cell Entry and Immune Evasion
Authors: Wenlin Ren, Xiaohui Ju, Mingli Gong, Jun Lan, Yanying Yu, Quanxin Long, Devin J Kenney, Aoife K O'Connell, Yu Zhang, Jin Zhong, Guocai Zhong, Florian Douam, Xinquan Wang, Ailong Huang, Rong Zhang, Qiang Ding
Journal: MBio
PubMed ID: 35266815
Doi: 10.1128/mbio.00099-22
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A Novel Anti-CD73 Antibody That Selectively Inhibits Membrane CD73 Shows Antitumor Activity and Induces Tumor Immune Escape
Authors: Markus Kellner, Bettina von Neubeck, Bastian Czogalla, Regina Feederle, Binje Vick, Irmela Jeremias, Reinhard Zeidler
Journal: Biomedicines
PubMed ID: 35453575
Doi: 10.3390/biomedicines10040825
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Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model
Authors: Julie A Zorn, Matthew L Wheeler, Ralston M Barnes, Jim Kaberna, Winse Morishige, Marek Harris, Richard Y-C Huang, Jack Lohre, Yu Ching Chang, Bryant Chau, Kathleen Powers, Ian Schindler, Naveen Neradugomma, Winston Thomas, Xiaoyun Liao, Yinhan Zhou, Sean M West, Feng Wang, Srikanth Kotapati, Guodong Chen, Sayumi Yamazoe, Anastasia Kosenko, Gavin Dollinger, Tim Sproul, Arvind Rajpal, Pavel Strop
Journal: Sci Rep
PubMed ID: 35241687
Doi: 10.1038/s41598-022-06953-7
Products & Services: Plasmid DNA Preparation   
Antibodies Targeting KSHV gH/gL Reveal Distinct Neutralization Mechanisms
Authors: Thomas Fricke, Anna K Großkopf, Armin Ensser, Marija Backovic, Alexander S Hahn
Journal: Viruses
PubMed ID: 35336948
Doi: 10.3390/v14030541
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Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture
Authors: Adam M Nock, Tina R Clark, Ted Hackstadt
Journal: MBio
PubMed ID: 35285700
Doi: 10.1128/mbio.00353-22
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Directed evolution of adeno-associated virus 5 capsid enables specific liver tropism
Authors: Yuqiu Wang, Chen Yang, Hanyang Hu, Chen Chen, Mengdi Yan, Feixiang Ling, Kathy Cheng Wang, Xintao Wang, Zhe Deng, Xinyue Zhou, Feixu Zhang, Sen Lin, Zengmin Du, Kai Zhao, Xiao Xiao
Journal: Mol Ther Nucleic Acids
PubMed ID: 35474733
Doi: 10.1016/j.omtn.2022.03.017
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Theileria equi RAP-1a and RAP-1b proteins contain immunoreactive epitopes and are suitable candidates for vaccine and diagnostics development
Authors: Cynthia K Onzere, Lindsay M Fry, Richard P Bishop, Marta Da Silva, Sally A Madsen-Bouterse, Reginaldo G Bastos, Donald P Knowles, Carlos E Suarez
Journal: Int J Parasitol
PubMed ID: 35318949
Doi: 10.1016/j.ijpara.2022.01.004
Products & Services: Recombinant Antibody Expression   
Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor
Authors: Haozhou Tan, Chunlong Ma, Jun Wang
Journal: Res Sq
PubMed ID: 35378761
Doi: 10.21203/rs.3.rs-1490282/v1
Products & Services: Codon Optimization   
Specificity and Reactivity of Serine/Threonine Kinases PknG and PknB
Authors: Osvaldo Burastero, Marisol Cabrera, Elias D Lopez, Lucas A Defelipe, Juan Pablo Arcon, Rosario Durán, Marcelo A Marti, Adrian G Turjanski
Journal: J Chem Inf Model
PubMed ID: 35319884
Doi: 10.1021/acs.jcim.1c01358
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Treatment Regimens for Transplant-Ineligible Patients With Newly Diagnosed Multiple Myeloma: A Systematic Literature Review and Network Meta-analysis
Authors: Thierry Facon, Jesús San-Miguel, Meletios A Dimopoulos, Maria-Victoria Mateos, Michele Cavo, Sophie van Beekhuizen, Zijiao Yuan, João Mendes, Annette Lam, Jianming He, Eric Ammann, Shaji Kumar
Journal: Adv Ther
PubMed ID: 35246820
Doi: 10.1007/s12325-022-02083-8
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Molnupiravir and Nirmatrelvir-Ritonavir: Oral COVID Antiviral Drugs
Authors: Louis D Saravolatz, Shawn Depcinski, Mamta Sharma
Journal: Clin Infect Dis
PubMed ID: 35245942
Doi: 10.1093/cid/ciac180
Structural polymorphism of coiled-coils from the stalk domain of SARS-CoV-2 spike protein
Authors: Zala Živič, Žiga Strmšek, Marko Novinec, Jurij Lah, San Hadži
Journal: FASEB J
PubMed ID: 35157347
Doi: 10.1096/fj.202101670R
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Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine
Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35149556
Doi: 10.1073/pnas.2119995119
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Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF melanoma
Authors: Lorey K Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P Kusnadi, Jian Kang, Claire A Martin, Peter Lau, Riyaben Patel, Julie Lorent, David Papadopoli, Anna Trigos, Teresa Ward, Aparna D Rao, Emily J Lelliott, Karen E Sheppard, David Goode, Rodney J Hicks, Tony Tiganis, Kaylene J Simpson, Ola Larsson, Benjamin Blythe, Carleen Cullinane, Vihandha O Wickramasinghe, Richard B Pearson, Grant A McArthur
Journal: Nat Commun
PubMed ID: 35232962
Doi: 10.1038/s41467-022-28705-x
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A novel silk fibroin protein-based fusion system for enhancing the expression of nanobodies in Escherichia coli
Authors: Jianli Yu, Yang Guo, Yi Gu, Xiying Fan, Fei Li, Haipeng Song, Rui Nian, Wenshuai Liu
Journal: Appl Microbiol Biotechnol
PubMed ID: 35243528
Doi: 10.1007/s00253-022-11857-7
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Erythroid differentiation in mouse erythroleukemia cells depends on Tmod3-mediated regulation of actin filament assembly into the erythroblast membrane skeleton
Authors: Arit Ghosh, Megan Coffin, Richard West, Velia M Fowler
Journal: FASEB J
PubMed ID: 35195928
Doi: 10.1096/fj.202101011R
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