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A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands

Authors: Micah Steffek, Elizabeth Helgason, Nataliya Popovych, Lionel Rougé, John M Bruning, Ke Sherry Li, Daniel J Burdick, Jianping Cai, Terry Crawford, Jing Xue, Willy Decurtins, Chunlin Fang, Felix Grubers, Michael J Holliday, Allyson Langley, Ann Petersen, Alexander Lee Satz, Aimin Song, Daniel Stoffler, Quentin Strebel, Jeffrey Y K Tom, Nicholas Skelton, Steven T Staben, Moreno Wichert, Melinda M Mulvihill, Erin C Dueber

Journal: Biochemistry

PubMed ID: 34985287

Doi: 10.1021/acs.biochem.1c00682

Products & Services: Gene Synthesis

Functional characterization of melanocortin-3 receptor in rainbow trout (Oncorhynchus mykiss)

Authors: Hui-Xia Yu, Yang Li, Wei-Jia Song, Hui Wang, Hao-Lin Mo, Qiao Liu, Xin-Miao Zhang, Ze-Bin Jiang, Li-Xin Wang

Journal: Fish Physiol Biochem

PubMed ID: 35098384

Doi: 10.1007/s10695-021-01033-5

Products & Services: Gene Synthesis

A transcriptional biosensor to monitor single cancer cell therapeutic responses by bioluminescence microscopy

Authors: Audrey Champagne, Pallavi Jain, Lauriane Vélot, Julie Riopel, Véronique Lefebvre, Bertrand Neveu, Frédéric Pouliot

Journal: Theranostics

PubMed ID: 34976196

Doi: 10.7150/thno.63744

Products & Services: Gene Synthesis

Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Authors: Siriorn P Watcharananan, Peera Jaru-Ampornpan, Suree Sahawongcharoen, Nattakan Naitook, Orawan Himananto, Anan Jongkaewwattana, Chavachol Setthaudom, Sasivimol Rattanasiri, Angsana Phuphuakrat, Ammarin Thakkinstian, Viroon Mavichak

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

Comparison of the immunogenicity of ChAdOx1 nCoV-19 vaccine against the wild-type and delta variants in kidney transplant recipients and healthy volunteers

Journal: Am J Transplant

PubMed ID: 35090091

Doi: 10.1111/ajt.16966

Products & Services: Recombinant Antibody Expression

K-edge anomalous SAXS for protein solution structure modeling

Authors: Karman Virk, Kento Yonezawa, Komal Choukate, Lucky Singh, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35102886

Doi: 10.1107/S205979832101247X

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High level production of stable human serum albumin in Pichia pastoris and characterization of the recombinant product

Authors: Nitu Maity, Avijeet S Jaswal, Ashwani Gautam, Vikram Sahai, Saroj Mishra

Journal: Bioprocess Biosyst Eng

PubMed ID: 34999948

Doi: 10.1007/s00449-021-02670-z

Products & Services: PCR Cloning and Subcloning

Antibody response following SARS-CoV-2 vaccination among patients with type 2 diabetes mellitus: A systematic review

Authors: Nanny Natalia M Soetedjo, Maria Riastuti Iryaningrum, Sherly Lawrensia, Hikmat Permana

Journal: Diabetes Metab Syndr

PubMed ID: 35104750

Doi: 10.1016/j.dsx.2022.102406

Products & Services: Protein Reagents and Products

Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection

Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang

Journal: Environ Sci Technol

PubMed ID: 35049283

Doi: 10.1021/acs.est.1c07172

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a Salmonella-based oral vaccine to control intestinal colonization of Shiga-toxin-producing Escherichia coli (STEC) in animals

Authors: Florencia Iannino, Paula J Uriza, Cecilia M Duarte, María V Pepe, Mara S Roset, Gabriel Briones

Journal: Vaccine

PubMed ID: 35086742

Doi: 10.1016/j.vaccine.2022.01.032

Products & Services: GenParts™ DNA Fragments

Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI9 norovirus, as revealed by structural analysis

Authors: Tomomi Kimura-Someya, Miyuki Kato-Murayama, Kazushige Katsura, Naoki Sakai, Kazutaka Murayama, Kazuharu Hanada, Mikako Shirouzu, Yuichi Someya

Journal: FEBS Open Bio

PubMed ID: 35038379

Doi: 10.1002/2211-5463.13370

Products & Services: GenParts™ DNA Fragments

Hybridization chain reaction circuit-based electrochemiluminescent biosensor for SARS-cov-2 RdRp gene assay

Authors: Kai Zhang, Zhenqiang Fan, Yue Huang, Yuedi Ding, Minhao Xie, Minghe Wang

Journal: Talanta

PubMed ID: 34998144

Doi: 10.1016/j.talanta.2022.123207

Products & Services: Gene Synthesis

Formation of Calprotectin-Derived Peptides in the Airways of Children with Cystic Fibrosis

Authors: Teagan S Edwards, Nina Dickerhof, Nicholas J Magon, Louise N Paton, Peter D Sly, Anthony J Kettle

Journal: J Immunol

PubMed ID: 35046105

Doi: 10.4049/jimmunol.2001017

Products & Services: Peptide Modifications

Characterization of male-biased fatty acid desaturase in the jewel wasp Nasonia vitripennis and its role in pheromone production

Authors: Jian-Qiu Cheng, Yu-Mei Tao, Jing Li, Yong-Zhuo Chen, Hao-Yuan Hu

Journal: J Exp Zool B Mol Dev Evol

PubMed ID: 34995007

Doi: 10.1002/jez.b.23120

Products & Services: Polyclonal Antibody Services

Identification, purification, and pharmacological activity analysis of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAα1) expressed in transgenic rabbit mammary glands

Authors: Ting Zhang, Minya Zhou, Heqing Cai, Kunning Yan, Yiwen Zha, Wenwen Zhuang, Jingyan Liang, Yong Cheng

Journal: Transgenic Res

PubMed ID: 35034272

Doi: 10.1007/s11248-021-00292-5

Products & Services: Gene Synthesis

Production and application of mouse monoclonal antibodies targeting linear epitopes in pB602L of African swine fever virus

Authors: Pengfei Wang, Chunguo Liu, Shida Wang, Lili Wen, Zhibin Shi, Yue Chi, Ming Wang, Zaisi Liu, Zhenzhao Sun, Lili Wei, Decheng Yang, Xijun He, Jingfei Wang

Journal: Arch Virol

PubMed ID: 34984562

Doi: 10.1007/s00705-021-05335-0

Products & Services: Custom Vector Construction

Survey of SARS-CoV-2 in dogs and cats in high-risk areas during the second wave of COVID-19 outbreak, Thailand

Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Aphinya Hangsawek, Suchart Waenkaew, Anek Mungaomklang, Ratanaporn Tangwangvivat, Alongkorn Amonsin

Journal: Zoonoses Public Health

PubMed ID: 34981900

Doi: 10.1111/zph.12907

Comparative Immunogenicity of the Recombinant Receptor-Binding Domain of Protein S SARS-CoV-2 Obtained in Prokaryotic and Mammalian Expression Systems

Authors: Iuliia A Merkuleva, Dmitry N Shcherbakov, Mariya B Borgoyakova, Daniil V Shanshin, Andrey P Rudometov, Larisa I Karpenko, Svetlana V Belenkaya, Anastasiya A Isaeva, Valentina S Nesmeyanova, Elena I Kazachinskaia, Ekaterina A Volosnikova, Tatiana I Esina, Anna V Zaykovskaya, Oleg V Pyankov, Sophia S Borisevich, Arseniya A Shelemba, Anton N Chikaev, Alexander A Ilyichev

Journal: Vaccines (Basel)

PubMed ID: 35062757

Doi: 10.3390/vaccines10010096

Products & Services: Mammalian Expression

SMARCA4 biology in alveolar rhabdomyosarcoma

Authors: Narendra Bharathy, Megan M Cleary, Jin-Ah Kim, Kiyo Nagamori, Kenneth A Crawford, Eric Wang, Debarya Saha, Teagan P Settelmeyer, Reshma Purohit, Damianos Skopelitis, Kenneth Chang, Jessica A Doran, C Ward Kirschbaum, Suriya Bharathy, Davis W Crews, Matthew E Randolph, Anthony N Karnezis, Lisa Hudson-Price, Jyotsna Dhawan, Joel E Michalek, Alessio Ciulli, Christopher R Vakoc, Charles Keller

Journal: Oncogene

PubMed ID: 35094009

Doi: 10.1038/s41388-022-02205-0

Products & Services: Gene Synthesis

Immunogenic Properties of MVs Containing Structural Hantaviral Proteins: An Original Study

Authors: Layaly Shkair, Ekaterina Evgenevna Garanina, Ekaterina Vladimirovna Martynova, Alena Igorevna Kolesnikova, Svetlana Sergeevna Arkhipova, Angelina Andreevna Titova, Albert Anatolevich Rizvanov, Svetlana Francevna Khaiboullina

Journal: Pharmaceutics

PubMed ID: 35056989

Doi: 10.3390/pharmaceutics14010093

Products & Services: Plasmid DNA Preparation PCR Cloning and Subcloning

Horizontal gene transfer as a mechanism for the promiscuous acquisition of distinct classes of IRES by avian caliciviruses

Authors: Yani Arhab, Anna Miścicka, Tatyana V Pestova, Christopher U T Hellen

Journal: Nucleic Acids Res

PubMed ID: 34928389

Doi: 10.1093/nar/gkab1243

Products & Services: Gene Synthesis

A glutathione-independent DJ-1/PfpI domain-containing tomato glyoxalaseIII2, SlGLYIII2, confers enhanced tolerance under salt and osmotic stresses

Authors: Priya Gambhir, Vijendra Singh, Utkarsh Raghuvanshi, Adwaita Prasad Parida, Amit Pareek, Abhishek Roychowdhury, Sudhir K Sopory, Rahul Kumar, Arun Kumar Sharma

Journal: Plant Cell Environ

PubMed ID: 36377315

Doi: 10.1111/pce.14493

Products & Services: Proteins, Expression, Isolation and Analysis

Inhibition of the transcription factor ZNF281 by SUFU to suppress tumor cell migration

Authors: Yanran Deng, Dezhen Peng, Jing Xiao, Yunhe Zhao, Wenhao Ding, Shengtao Yuan, Li Sun, Jian Ding, Zizhang Zhou, Meixiao Zhan

Journal: Cell Death Differ

PubMed ID: 36220888

Doi: 10.1038/s41418-022-01073-1

Products & Services: Codon Optimization

Development of peptide affinity ligands for the purification of polyclonal and monoclonal Fabs from recombinant fluids

Authors: Ryan Kilgore, Wenning Chu, Dipendra Bhandari, David Fischler, Ruben G Carbonell, Michael Crapanzano, Stefano Menegatti

Journal: J Chromatogr A

PubMed ID: 36502645

Doi: 10.1016/j.chroma.2022.463701

Products & Services: Proteins, Expression, Isolation and Analysis

Modification of soy protein isolate using dielectric barrier discharge cold plasma assisted by modified atmosphere packaging

Authors: Qi Li, Fei Shen, Xueming He, Changrui Xing, Wenjing Yan, Yong Fang, Qiuhui Hu

Journal: Food Chem

PubMed ID: 36099827

Doi: 10.1016/j.foodchem.2022.134158

Products & Services: Proteins, Expression, Isolation and Analysis

Gel-Forming of Self-Assembling Peptides Functionalized with Food Bioactive Motifs Modulate DPP-IV and ACE Inhibitory Activity in Human Intestinal Caco-2 Cells

Authors: Raffaele Pugliese, Martina Bartolomei, Carlotta Bollati, Giovanna Boschin, Anna Arnoldi, Carmen Lammi

Journal: Biomedicines

PubMed ID: 35203539

Doi: 10.3390/biomedicines10020330

Products & Services: Catalog Peptides

A Bursaphelenchus xylophilus pathogenic protein Bx-FAR-1, as potential control target, mediates the jasmonic acid pathway in pines

Authors: Tong-Yue Wen, Xiao-Qin Wu, Jian-Ren Ye, Yi-Jun Qiu, Lin Rui, Yan Zhang

Journal: Pest Manag Sci

PubMed ID: 35060311

Doi: 10.1002/ps.6805

Products & Services: Recombinant Antibody Expression

The Role of CD147 in Pathological Cardiac Hypertrophy Is Regulated by Glycosylation

Authors: Fang-Yuan Zhong, Yi-Chao Zhao, Chen-Xu Zhao, Zhi-Chun Gu, Xi-Yuan Lu, Wen-Long Jiang, Ling-Chen Gao, Wen-Li Li, Zi-Han Qin, Heng Ge, Jun Pu

Journal: Oxid Med Cell Longev

PubMed ID: 35096272

Doi: 10.1155/2022/6603296

Products & Services: Proteins, Expression, Isolation and Analysis

Exploring the underlying mechanisms on NaCl-induced reduction in digestibility of myoglobin

Authors: Hui Liu, Qian Li, Shuai Jiang, Miao Zhang, Di Zhao, Kai Shan, Chunbao Li

Journal: Food Chem

PubMed ID: 35077987

Doi: 10.1016/j.foodchem.2022.132183

Products & Services: Proteins, Expression, Isolation and Analysis

Introducing an Artificial Deazaflavin Cofactor in and

Authors: Misun Lee, Jeroen Drenth, Milos Trajkovic, René M de Jong, Marco W Fraaije

Journal: ACS Synth Biol

PubMed ID: 35044755

Doi: 10.1021/acssynbio.1c00552

Products & Services: Bacterial Expression

Expression, Purification, and Biophysical Characterization of Klebsiella Pneumoniae Nicotinate Nucleotide Adenylyltransferase

Authors: Tasvi Daya, Olamide Jeje, Reabetswe Maake, Chinyere Aloke, Thandeka Khoza, Ikechukwu Achilonu

Journal: Protein J

PubMed ID: 35083643

Doi: 10.1007/s10930-021-10037-2

Products & Services: Custom Vector Construction

The H, N and C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1

Authors: Courtney N Johnson, Xiaoping Xu, Stephen P Holloway, David S Libich

Journal: Biomol NMR Assign

PubMed ID: 34994941

Doi: 10.1007/s12104-021-10061-4

Products & Services: Mutant Libraries

Hemagglutinin-based DNA vaccines containing trimeric self-assembling nanoparticles confer protection against influenza

Authors: Yongbo Qiao, Shenghui Jin, Jiaojiao Nie, Yaotian Chang, Bo Wang, Shanshan Guan, Qinghan Li, Yuhua Shi, Wei Kong, Yaming Shan

Journal: J Leukoc Biol

PubMed ID: 35040188

Doi: 10.1002/JLB.6A1021-535R

Products & Services: Mammalian Expression

lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway

Authors: Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang

Journal: Mediators Inflamm

PubMed ID: 35125964

Doi: 10.1155/2022/6979117

Products & Services: Custom DNA/RNA Oligos

Anti-Coagulant and Antimicrobial Recombinant Heparin-Binding Major Ampullate Spidroin 2 (MaSp2) Silk Protein

Authors: Pranothi Mulinti, Dorina Diekjürgen, Kristen Kurtzeborn, Narayanaganesh Balasubramanian, Shane J Stafslien, David W Grainger, Amanda E Brooks

Journal: Bioengineering (Basel)

PubMed ID: 35200400

Doi: 10.3390/bioengineering9020046

Products & Services: Gene Synthesis

Anti-Coagulant and Antimicrobial Recombinant Heparin-Binding Major Ampullate Spidroin 2 (MaSp2) Silk Protein

Authors: Pranothi Mulinti, Dorina Diekjürgen, Kristen Kurtzeborn, Narayanaganesh Balasubramanian, Shane J Stafslien, David W Grainger, Amanda E Brooks

Journal: Bioengineering (Basel)

PubMed ID: 35200400

Doi: 10.3390/bioengineering9020046

Products & Services: Gene Synthesis

Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor

Authors: Jinliang Wang, Jie Luo, Zhiyuan Wen, Xinxin Wang, Lei Shuai, Gongxun Zhong, Chong Wang, Ziruo Sun, Weiye Chen, Jinying Ge, Renqiang Liu, Xijun Wang, Zhigao Bu

Journal: MBio

PubMed ID: 35012335

Doi: 10.1128/mbio.02443-21

Products & Services: Proteins, Expression, Isolation and Analysis

Anti-aquaporin-4 immunoglobulin G colorimetric detection by silver nanoparticles

Authors: Akemi M Higa, Ariana S Moraes, Flávio M Shimizu, Raquel G Bueno, Luís A Peroni, Francisco T Strixino, Nise A C Sousa, Elenice Deffune, Ana Lívia C Bovolato, Osvaldo N Oliveira, Doralina G Brum, Fabio L Leite

Journal: Nanomedicine

PubMed ID: 35114406

Doi: 10.1016/j.nano.2022.102531

Products & Services: Catalog Peptides

Genome-wide identification and expression pattern analysis of the TCP transcription factor family in

Authors: Li Yu, Qiangwen Chen, Jiarui Zheng, Feng Xu, Jiabao Ye, Weiwei Zhang, Yongling Liao, Xiaoyan Yang

Journal: Plant Signal Behav

PubMed ID: 35068346

Doi: 10.1080/15592324.2021.1994248

Products & Services: Protein Tools

Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses primed by an injected vaccine

Authors: Jacob Pitcovski, Nady Gruzdev, Anna Abzach, Chen Katz, Ran Ben-Adiva, Michal Brand-Shwartz, Itamar Yadid, Einav Ratzon-Ashkenazi, Ken Emquies, Hadasa Israeli, Hadar Haviv, Irena Rapoport, Itai Bloch, Roy Shadmon, Zohar Eitan, Dalia Eliahu, Talia Hilel, Morris Laster, Sigal Kremer-Tal, Tamara Byk-Tennenbaum, Ehud Shahar

Journal: Vaccine

PubMed ID: 35078662

Doi: 10.1016/j.vaccine.2022.01.025

Products & Services: Proteins, Expression, Isolation and Analysis

Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells

Authors: Xiaohong Zhang, Stephen H Wright

Journal: Int J Mol Sci

PubMed ID: 35163393

Doi: 10.3390/ijms23031472

Products & Services: Catalog Antibody

Assessment on anti-SARS-CoV-2 receptor-binding domain antibodies among CoronaVac-vaccinated Indonesian adults

Authors: Juandy Jo, Astia Sanjaya, Reinhard Pinontoan, Maroloan Aruan, Rury Mega Wahyuni, Venansi Viktaria

Journal: Clin Exp Vaccine Res

PubMed ID: 35223672

Doi: 10.7774/cevr.2022.11.1.116

Products & Services: Proteins, Expression, Isolation and Analysis

Expression of phenylalanine ammonia lyases in Synechocystis sp PCC 6803 and subsequent improvements of sustainable production of phenylpropanoids

Authors: Kateryna Kukil, Pia Lindberg

Journal: Microb Cell Fact

PubMed ID: 35012528

Doi: 10.1186/s12934-021-01735-8

Products & Services: Codon Optimization

Genome-wide analysis and transcriptional reprogrammings of MYB superfamily revealed positive insights into abiotic stress responses and anthocyanin accumulation in Carthamus tinctorius L

Authors: Yingqi Hong, Naveed Ahmad, Jianyi Zhang, Yanxi Lv, Xinyue Zhang, Xintong Ma, Liu Xiuming, Yao Na

Journal: Mol Genet Genomics

PubMed ID: 34978004

Doi: 10.1007/s00438-021-01839-1

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Different Functions of , a Drought-Responsive AP2/ERF Transcription Factor, in Regulating Root Development Between and Sweetpotato

Authors: Xiaofeng Bian, Ho Soo Kim, Sang-Soo Kwak, Qian Zhang, Shuai Liu, Peiyong Ma, Zhaodong Jia, Yizhi Xie, Peng Zhang, Yang Yu

Journal: Front Plant Sci

PubMed ID: 35154229

Doi: 10.3389/fpls.2022.820450

Products & Services: Molecular Biology Tools

Heterotrimeric Gq proteins act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias

Authors: Kouki Kawakami, Masataka Yanagawa, Suzune Hiratsuka, Misaki Yoshida, Yuki Ono, Michio Hiroshima, Masahiro Ueda, Junken Aoki, Yasushi Sako, Asuka Inoue

Journal: Nat Commun

PubMed ID: 35078997

Doi: 10.1038/s41467-022-28056-7

Products & Services: Peptide Synthesis

Cell membrane-anchored and tumor-targeted IL-12 (attIL12)-T cell therapy for eliminating large and heterogeneous solid tumors

Authors: Jiemiao Hu, Qing Yang, Wendong Zhang, Hongwei Du, Yuhui Chen, Qingnan Zhao, Long Dao, Xueqing Xia, Fowlkes Natalie Wall, Zhongting Zhang, Kris Mahadeo, Richard Gorlick, S Kopetz, Gianpietro Dotti, Shulin Li

Journal: J Immunother Cancer

PubMed ID: 35027427

Doi: 10.1136/jitc-2021-003633

Products & Services: Mammalian Expression

Blue-light receptor phototropin 1 suppresses immunity to promote Phytophthora infestans infection

Authors: Shaista Naqvi, Qin He, Franziska Trusch, Huishan Qiu, Jasmine Pham, Qingguo Sun, John M Christie, Eleanor M Gilroy, Paul R J Birch

Journal: New Phytol

PubMed ID: 34923631

Doi: 10.1111/nph.17929

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Sterility of Sustained-release Buprenorphine

Authors: Shraddha I Cantara, Crystal Gergye, Vanessa K Lee, Michael Huerkamp

Journal: J Am Assoc Lab Anim Sci

PubMed ID: 35082006

Doi: 10.30802/AALAS-JAALAS-21-000105

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ADAM17 regulates the proliferation and extracellular matrix of keloid fibroblasts by mediating the EGFR/ERK signaling pathway

Authors: Xin Le, You-Fen Fan

Journal: J Plast Surg Hand Surg

PubMed ID: 34978504

Doi: 10.1080/2000656X.2021.2017944

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Investigation of putative antimicrobial peptides in Carassius gibel, revealing a practical approach to screening antimicrobials

Authors: Yujun Zhang, Ping Deng, Caijiao Dai, Mengke Wu, Xueqin Liu, Lijuan Li, Xiaoyi Pan, Junfa Yuan

Journal: Fish Shellfish Immunol

PubMed ID: 34990806

Doi: 10.1016/j.fsi.2021.12.050

Products & Services: Recombinant Proteins

Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells

Authors: Bruna Cristina Falavinha, María Julia Barisón, Carmen Lúcia Kuniyoshi Rebelatto, Bruna Hilzendeger Marcon, Alessandra de Melo Aguiar, Evelin Brandão da Silva, Marco Augusto Stimamiglio, Patrícia Shigunov

Journal: Stem Cells Int

PubMed ID: 35047041

Doi: 10.1155/2022/4930932

Products & Services: ORF cDNA Clones/MolecularCloud

Inhibition of microRNA-448 suppresses CD4 T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus

Authors: Jing Zhang, Yun Guo, Yue Sun, Lihua Chang, Xiaofei Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 35121374

Doi: 10.1016/j.bbrc.2022.01.097

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Hempseed () Peptides WVSPLAGRT and IGFLIIWV Exert Anti-inflammatory Activity in the LPS-Stimulated Human Hepatic Cell Line

Authors: Ivan Cruz-Chamorro, Guillermo Santos-Sánchez, Carlotta Bollati, Martina Bartolomei, Jianqiang Li, Anna Arnoldi, Carmen Lammi

Journal: J Agric Food Chem

PubMed ID: 35007086

Doi: 10.1021/acs.jafc.1c07520

Products & Services: Proteins, Expression, Isolation and Analysis

NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway

Authors: Bo Li, Qian Xiao, Liping Shan, Yongsheng Song

Journal: Cell Cycle

PubMed ID: 34974790

Doi: 10.1080/15384101.2021.2021050

Products & Services: Plasmid DNA Preparation

Degradation of dimethachlon by a newly isolated bacterium Paenarthrobacter sp strain JH-1 relieves its toxicity against Chlorella ellipsoidea

Authors: Mingliang Zhang, Wankui Jiang, Siyuan Gao, Qian Zhu, Zhijian Ke, Mingli Jiang, Jiguo Qiu, Qing Hong

Journal: Environ Res

PubMed ID: 35031339

Doi: 10.1016/j.envres.2022.112706

Products & Services: Gene Synthesis

Clinical Potential of lncRNA PPP1R26-AS1 in Breast Cancer and Its Contribution to Cancer Progression

Authors: Shuping Zhou, Shaoli Zhang, Hui Zhang, Junxia Ma, Huangzhen Dai, Lili Qu, Meixiang Zhou

Journal: Mol Biotechnol

PubMed ID: 35064892

Doi: 10.1007/s12033-022-00452-w

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Mesenchymal Stem Cell-Derived Exosomes Improved Cerebral Infarction via Transferring miR-23a-3p to Activate Microglia

Authors: Chenglong Dong, Maogang Chen, Binggang Cai, Cheng Zhang, Guodong Xiao, Weifeng Luo

Journal: Neuromolecular Med

PubMed ID: 35001328

Doi: 10.1007/s12017-021-08686-8

Products & Services: ORF cDNA Clones/MolecularCloud

Genome-Wide Identification and Expression Profile Analysis of the SnRK2 Gene Family in Nicotiana tabacum

Authors: Jinghao Li, Jiangyu Song, Changjun Li, Juntao Ma, Jiawang Liu, Xiaowei Zhu, Jingchao Li, Fan He, Chao Yang

Journal: Biochem Genet

PubMed ID: 35048221

Doi: 10.1007/s10528-021-10170-8

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RBP4 regulates androgen receptor expression and steroid synthesis in Sertoli cells from Bactrian camels

Authors: Qi Wang, Quanwei Zhang, Yina Li, Xingxu Zhao, Yong Zhang

Journal: Reprod Domest Anim

PubMed ID: 35014100

Doi: 10.1111/rda.14081

Products & Services: Plasmid DNA Preparation

Selection and T-cell antigenicity of synthetic long peptides derived from SARS-CoV-2

Authors: Katarzyna Piadel, Amin Haybatollahi, Angus George Dalgleish, Peter Lawrence Smith

Journal: J Gen Virol

PubMed ID: 35014605

Doi: 10.1099/jgv.0.001698

Products & Services: Peptide Synthesis

An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein

Authors: Yahiro Mukai, Masayuki Horie, Shohei Kojima, Junna Kawasaki, Ken Maeda, Keizo Tomonaga

Journal: FEBS Lett

PubMed ID: 35043395

Doi: 10.1002/1873-3468.14290

Products & Services: Recombinant Antibody Expression

Protocol for structure determination of SARS-CoV-2 main protease at near-physiological-temperature by serial femtosecond crystallography

Authors: Fatma Betul Ertem, Omur Guven, Cengizhan Buyukdag, Oktay Gocenler, Esra Ayan, Busra Yuksel, Mehmet Gul, Gozde Usta, Barıs Cakılkaya, J Austin Johnson, E Han Dao, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Brandon Hayes, Mengning Liang, Mark S Hunter, Alexander Batyuk, Raymond G Sierra, Gihan Ketawala, Sabine Botha, Çağdaş Dağ, Hasan DeMirci

Journal: STAR Protoc

PubMed ID: 35194584

Doi: 10.1016/j.xpro.2022.101158

Products & Services: Proteins, Expression, Isolation and Analysis

Anion binding to a cationic europium(III) probe enables the first real-time assay of heparan sulfotransferase activity

Authors: Simon Wheeler, Colum Breen, Yong Li, Sarah H Hewitt, Erin Robertson, Edwin A Yates, Igor L Barsukov, David G Fernig, Stephen J Butler

Journal: Org Biomol Chem

PubMed ID: 34951618

Doi: 10.1039/d1ob02071d

Products & Services: Proteins, Expression, Isolation and Analysis

Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue

Authors: Yingzi Tan, Miao Wang, Yijun Chen

Journal: ACS Synth Biol

PubMed ID: 35006674

Doi: 10.1021/acssynbio.1c00578

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H3K9 Methyltransferases Suv39h1 and Suv39h2 Control the Differentiation of Neural Progenitor Cells in the Adult Hippocampus

Authors: Miguel V Guerra, Matías I Cáceres, Andrea Herrera-Soto, Sebastián B Arredondo, Manuel Varas-Godoy, Brigitte van Zundert, Lorena Varela-Nallar

Journal: Front Cell Dev Biol

PubMed ID: 35096813

Doi: 10.3389/fcell.2021.778345

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Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance

Authors: Gabriel Therizols, Zeina Bash-Imam, Baptiste Panthu, Christelle Machon, Anne Vincent, Julie Ripoll, Sophie Nait-Slimane, Mounira Chalabi-Dchar, Angéline Gaucherot, Maxime Garcia, Florian Laforêts, Virginie Marcel, Jihane Boubaker-Vitre, Marie-Ambre Monet, Céline Bouclier, Christophe Vanbelle, Guillaume Souahlia, Elise Berthel, Marie Alexandra Albaret, Hichem C Mertani, Michel Prudhomme, Martin Bertrand, Alexandre David, Jean-Christophe Saurin, Philippe Bouvet, Eric Rivals, Théophile Ohlmann, Jérôme Guitton, Nicole Dalla Venezia, Julie Pannequin, Frédéric Catez, Jean-Jacques Diaz

Journal: Nat Commun

PubMed ID: 35013311

Doi: 10.1038/s41467-021-27847-8

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CD46 Isoforms Influence the Mode of Entry by Human Herpesvirus 6A/B in T Cells

Authors: Litten Sørensen Rossen, Vivien R Schack, Katrine Kyd Holstein Thuesen, Bettina Bundgaard, Per Höllsberg

Journal: J Virol

PubMed ID: 35019717

Doi: 10.1128/JVI.01557-21

Products & Services: Proteins, Expression, Isolation and Analysis

Whole-genome-scale identification of novel non-protein-coding RNAs controlling cell proliferation and survival through a functional forward genetics strategy

Authors: D P Tonge, D Darling, F Farzaneh, G T Williams

Journal: Sci Rep

PubMed ID: 34997014

Doi: 10.1038/s41598-021-03983-5

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Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage

Authors: Yannik Bollen, Joris H Hageman, Petra van Leenen, Lucca L M Derks, Bas Ponsioen, Julian R Buissant des Amorie, Ingrid Verlaan-Klink, Myrna van den Bos, Leon W M M Terstappen, Ruben van Boxtel, Hugo J G Snippert

Journal: PLoS Biol

PubMed ID: 35089911

Doi: 10.1371/journal.pbio.3001527

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Comparison of Carbonic Anhydrases for CO Sequestration

Authors: Franziska Steger, Johanna Reich, Werner Fuchs, Simon K-M R Rittmann, Georg M Gübitz, Doris Ribitsch, Günther Bochmann

Journal: Int J Mol Sci

PubMed ID: 35055147

Doi: 10.3390/ijms23020957

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Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2

Authors: Kapil Gupta, Christine Toelzer, Maia Kavanagh Williamson, Deborah K Shoemark, A Sofia F Oliveira, David A Matthews, Abdulaziz Almuqrin, Oskar Staufer, Sathish K N Yadav, Ufuk Borucu, Frederic Garzoni, Daniel Fitzgerald, Joachim Spatz, Adrian J Mulholland, Andrew D Davidson, Christiane Schaffitzel, Imre Berger

Journal: Nat Commun

PubMed ID: 35017512

Doi: 10.1038/s41467-021-27881-6

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Humoral Immune Response in IBD Patients Three and Six Months after Vaccination with the SARS-CoV-2 mRNA Vaccines mRNA-1273 and BNT162b2

Authors: Richard Vollenberg, Phil-Robin Tepasse, Joachim Ewald Kühn, Marc Hennies, Markus Strauss, Florian Rennebaum, Tina Schomacher, Göran Boeckel, Eva Lorentzen, Arne Bokemeyer, Tobias Max Nowacki

Journal: Biomedicines

PubMed ID: 35052849

Doi: 10.3390/biomedicines10010171

Ultrasound-mediated gene delivery of factor VIII plasmids for hemophilia A gene therapy in mice

Authors: Shuxian Song, Meghan J Lyle, Misty L Noble-Vranish, Dominic M Min-Tran, James Harrang, Weidong Xiao, Evan C Unger, Carol H Miao

Journal: Mol Ther Nucleic Acids

PubMed ID: 35141050

Doi: 10.1016/j.omtn.2022.01.006

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Optimization of Thymidine Kinase-Based Safety Switch for Neural Cell Therapy

Authors: Manon Locatelli, Flavien Delhaes, Ophélie Cherpin, Margaret E Black, Stéphanie Carnesecchi, Olivier Preynat-Seauve, Youssef Hibaoui, Karl-Heinz Krause

Journal: Cells

PubMed ID: 35159311

Doi: 10.3390/cells11030502

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A mitochondrial ADXR-ADX-P450 electron transport chain is essential for maternal gametophytic control of embryogenesis in

Authors: Andrés Martin Bellido, Ayelén Mariana Distéfano, Nicolás Setzes, María Milagros Cascallares, Jana Oklestkova, Ondrej Novak, Javier Alberto Ramirez, Eduardo J Zabaleta, Diego F Fiol, Gabriela C Pagnussat

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35046016

Doi: 10.1073/pnas.2000482119

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BrnQ-Type Branched-Chain Amino Acid Transporters Influence Bacillus anthracis Growth and Virulence

Authors: Soumita Dutta, Ileana D Corsi, Naomi Bier, Theresa M Koehler

Journal: MBio

PubMed ID: 35073743

Doi: 10.1128/mbio.03640-21

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Effects of the Chloroplast Fructose-1,6-Bisphosphate Aldolase Gene on Growth and Low-Temperature Tolerance of Tomato

Authors: Bingbing Cai, Yu Ning, Qiang Li, Qingyun Li, Xizhen Ai

Journal: Int J Mol Sci

PubMed ID: 35054921

Doi: 10.3390/ijms23020728

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Hyperproduction of PHA copolymers containing high fractions of 4-hydroxybutyrate (4HB) by outer membrane-defected Halomonas bluephagenesis grown in bioreactors

Authors: Ziyu Wang, Yifei Zheng, Mengke Ji, Xu Zhang, Huan Wang, Yuemeng Chen, Qiong Wu, Guo-Qiang Chen

Journal: Microb Biotechnol

PubMed ID: 34978757

Doi: 10.1111/1751-7915.13999

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Zika virus baculovirus-expressed envelope protein elicited humoral and cellular immunity in immunocompetent mice

Authors: Minna Shin, Kiju Kim, Hyo-Ji Lee, Rangyeon Lee, Yu-Jin Jung, Jeongho Park, Tae-Wook Hahn

Journal: Sci Rep

PubMed ID: 35027643

Doi: 10.1038/s41598-021-04713-7

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SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons

Authors: Hila Asraf, Milos Bogdanovic, Noa Gottesman, Israel Sekler, Elias Aizenman, Michal Hershfinkel

Journal: iScience

PubMed ID: 35118363

Doi: 10.1016/j.isci.2022.103751

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Immunity to Sda1 Protects against Infection by Sda1 and Sda1 Serotypes of Group A

Authors: Shuai Bi, Jie Wang, Meiyi Xu, Ning Li, Beinan Wang

Journal: Vaccines (Basel)

PubMed ID: 35062763

Doi: 10.3390/vaccines10010102

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Alamandine alleviates hypertension and renal damage via oxidative-stress attenuation in Dahl rats

Authors: Juexiao Gong, Man Luo, Yonghong Yong, Shan Zhong, Peng Li

Journal: Cell Death Discov

PubMed ID: 35022384

Doi: 10.1038/s41420-022-00822-y

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Time-Prolonged Release of Tumor-Targeted Protein-MMAE Nanoconjugates from Implantable Hybrid Materials

Authors: Naroa Serna, Aïda Falgàs, Annabel García-León, Ugutz Unzueta, Yáiza Núñez, Alejandro Sánchez-Chardi, Carlos Martínez-Torró, Ramón Mangues, Esther Vazquez, Isolda Casanova, Antonio Villaverde

Journal: Pharmaceutics

PubMed ID: 35057088

Doi: 10.3390/pharmaceutics14010192

Products & Services: Proteins, Expression, Isolation and Analysis

Plant expression systems as an economical alternative for the production of iELISA coating antigen AHSV VP7

Authors: Shelley H Fearon, Susan J Dennis, Inga I Hitzeroth, Edward P Rybicki, Ann E Meyers

Journal: N Biotechnol

PubMed ID: 35114407

Doi: 10.1016/j.nbt.2022.01.009

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Stem-like breast cancer cells in the activated state resist genetic stress via TGFBI-ZEB1

Authors: Qi Sun, Yufen Wang, Adam Officer, Brianna Pecknold, Garrett Lee, Olivier Harismendy, Jay S Desgrosellier

Journal: NPJ Breast Cancer

PubMed ID: 35027548

Doi: 10.1038/s41523-021-00375-w

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Proline-specific aminopeptidase P prevents replication-associated genome instability

Authors: Nicola Silva, Maikel Castellano-Pozo, Kenichiro Matsuzaki, Consuelo Barroso, Monica Roman-Trufero, Hannah Craig, Darren R Brooks, R Elwyn Isaac, Simon J Boulton, Enrique Martinez-Perez

Journal: PLoS Genet

PubMed ID: 35081133

Doi: 10.1371/journal.pgen.1010025

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USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma

Authors: Yang Chen, Yin Zhao, Xiaojing Yang, Xianyue Ren, Shengyan Huang, Sha Gong, Xirong Tan, Junyan Li, Shiwei He, Yingqin Li, Xiaohong Hong, Qian Li, Cong Ding, Xueliang Fang, Jun Ma, Na Liu

Journal: Nat Commun

PubMed ID: 35079021

Doi: 10.1038/s41467-022-28158-2

Products & Services: Proteins, Expression, Isolation and Analysis

Precise exogenous insertion and sequence replacements in poplar by simultaneous HDR overexpression and NHEJ suppression using CRISPR-Cas9

Authors: Ali Movahedi, Hui Wei, Xiaohong Zhou, Jake C Fountain, Zhong-Hua Chen, Zhiying Mu, Weibo Sun, Jiaxin Zhang, Dawei Li, Baozhu Guo, Rajeev K Varshney, Liming Yang, Qiang Zhuge

Journal: Hortic Res

PubMed ID: 36133672

Doi: 10.1093/hr/uhac154

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Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease

Authors: Lucía Barbier-Torres, Ben Murray, Jin Won Yang, Jiaohong Wang, Michitaka Matsuda, Aaron Robinson, Aleksandra Binek, Wei Fan, David Fernández-Ramos, Fernando Lopitz-Otsoa, Maria Luque-Urbano, Oscar Millet, Nirmala Mavila, Hui Peng, Komal Ramani, Roberta Gottlieb, Zhaoli Sun, Suthat Liangpunsakul, Ekihiro Seki, Jennifer E Van Eyk, Jose M Mato, Shelly C Lu

Journal: Nat Commun

PubMed ID: 35091576

Doi: 10.1038/s41467-022-28201-2

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Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes

Authors: Melody Gao, D Alex Johnson, Isabel M Piper, Hanna M Kodama, Justin E Svendsen, Elise Tahti, Frederick Longshore-Neate, Brandon Vogel, John M Antos, Jeanine F Amacher

Journal: Protein Sci

PubMed ID: 34939250

Doi: 10.1002/pro.4266

Products & Services: Proteins, Expression, Isolation and Analysis

A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca signalling through IP receptors

Authors: Andrew R Lavik, Karen S McColl, Fernanda O Lemos, Martijn Kerkhofs, Fei Zhong, Michael Harr, Daniela Schlatzer, Kozo Hamada, Katsuhiko Mikoshiba, Francesco Crea, Geert Bultynck, Martin D Bootman, Jan B Parys, Clark W Distelhorst

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 35026348

Doi: 10.1016/j.bbamcr.2021.119206

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MicroRNA analysis reveals the role of miR-214 in duck adipocyte differentiation

Authors: Laidi Wang, Xiaodan Hu, Shasha Wang, Chunyou Yuan, Zhixiu Wang, Guobin Chang, Guohong Chen

Journal: Anim Biosci

PubMed ID: 35073666

Doi: 10.5713/ab.21.0441

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Omicron infection of vaccinated individuals enhances neutralizing immunity against the Delta variant

Authors: Khadija Khan, Farina Karim, Sandile Cele, James Emmanuel San, Gila Lustig, Houriiyah Tegally, Yuval Rosenberg, Mallory Bernstein, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Nokuthula Ngcobo, Yoliswa Miya, Matilda Mazibuko, Ntombifuthi Mthabela, Zoey Mhlane, Nikiwe Mbatha, Jennifer Giandhari, Yajna Ramphal, Taryn Naidoo, Nithendra Manickchund, Nombulelo Magula, Salim Abdool Karim, Glenda Gray, Willem Hanekom, Anne von Gottberg, Ron Milo, Bernadett Gosnell, Richard Lessells, Tulio de Oliveira, Penny Moore, Yunus S Moosa, Alex Sigal

Journal: medrxiv

PubMed ID: 34981076

Doi: 10.1101/2021.12.27.21268439

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Quantitation of Trastuzumab and an Antibody to SARS-CoV-2 in Minutes Using Affinity Membranes in 96-Well Plates

Authors: Hui Yin Tan, Junyan Yang, Jacqueline C Linnes, Christopher J Welch, Merlin L Bruening

Journal: Anal Chem

PubMed ID: 34982935

Doi: 10.1021/acs.analchem.1c03654

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Development of a radioiodinated thioflavin-T-Congo-red hybrid probe for diagnosis of systemic amyloidosis

Authors: Yoshie Haratake, Kohei Sano, Miki Tsuchiya, Kaori Minaki, Masayuki Munekane, Toshihide Yamasaki, Masayori Hagimori, Takahiro Mukai

Journal: Bioorg Med Chem

PubMed ID: 35033883

Doi: 10.1016/j.bmc.2021.116591

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A network of Gα signaling partners is revealed by proximity labeling proteomics analysis and includes PDZ-RhoGEF

Authors: Naincy R Chandan, Saji Abraham, Shuvasree SenGupta, Carole A Parent, Alan V Smrcka

Journal: Sci Signal

PubMed ID: 35041463

Doi: 10.1126/scisignal.abi9869

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Personalized therapy with peptide-based neoantigen vaccine (EVX-01) including a novel adjuvant, CAF®09b, in patients with metastatic melanoma

Authors: Sofie Kirial Mørk, Mohammad Kadivar, Kalijn Fredrike Bol, Arianna Draghi, Marie Christine Wulff Westergaard, Signe Koggersbøl Skadborg, Nana Overgaard, Anders Bundgård Sørensen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Christina Westmose Yde, Thomas Trolle, Christian Garde, Jens Friis-Nielsen, Nis Nørgaard, Dennis Christensen, Jens Vindahl Kringelum, Marco Donia, Sine Reker Hadrup, Inge Marie Svane

Journal: Oncoimmunology

PubMed ID: 35036074

Doi: 10.1080/2162402X.2021.2023255

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Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide

Authors: Nathalie Vanderheijden, Annelies Stevaert, Jiexiong Xie, Xiaolei Ren, Cyril Barbezange, Sam Noppen, Isabelle Desombere, Bruno Verhasselt, Peter Geldhof, Nick Vereecke, Veerle Stroobants, Dayoung Oh, Merijn Vanhee, Lieve M J Naesens, Hans J Nauwynck

Journal: Front Immunol

PubMed ID: 35069571

Doi: 10.3389/fimmu.2021.790415

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Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life

Authors: Algirdas Grevys, Rahel Frick, Simone Mester, Karine Flem-Karlsen, Jeannette Nilsen, Stian Foss, Kine Marita Knudsen Sand, Thomas Emrich, Jens Andre Alexander Fischer, Victor Greiff, Inger Sandlie, Tilman Schlothauer, Jan Terje Andersen

Journal: iScience

PubMed ID: 35118359

Doi: 10.1016/j.isci.2022.103746

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