客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 69/514 每页显示数量

Preparation and characterization of 2-deacetyl-3-O-sulfo-heparosan and its antitumor effects via the fibroblast growth factor receptor pathway

Authors: Zhengqi Zha, Yaoyao Liu, Yinghua Miao, Shiying Liao, Su-Yan Wang, Huiling Tang, Hongping Yin

Journal: Int J Biol Macromol

PubMed ID: 34998873

Doi: 10.1016/j.ijbiomac.2021.12.098

Products & Services: Plasmid DNA Preparation

Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

Products & Services: Codon Optimization

Nitroreduction of flutamide by NADPH: Cytochrome P450 reductase

Authors: Mohd Faheem Khan, Cormac D Murphy

Journal: Biochem Biophys Rep

PubMed ID: 35097225

Doi: 10.1016/j.bbrep.2022.101209

Products & Services: Codon Optimization

Bio-nanocapsules for oriented immobilization of DNA aptamers on aptasensors

Authors: Masumi Iijima, Yuki Yamada, Hideo Nakano, Tsutomu Nakayama, Shun'ichi Kuroda

Journal: Analyst

PubMed ID: 35023508

Doi: 10.1039/d1an02278d

Products & Services: GenParts™ DNA Fragments

Longitudinal waning of mRNA vaccine-induced neutralizing antibodies against SARS-CoV-2 detected by an LFIA rapid test

Authors: Qiao Wang, Lili Feng, Haohai Zhang, Juehua Gao, Changchuin Mao, Esther Landesman-Bollag, Gustavo Mostoslavsky, Justin M Lunderberg, Weina Zheng, Shushun Hao, Wenda Gao

Journal: Antib Ther

PubMed ID: 35146332

Doi: 10.1093/abt/tbac004

Products & Services: Proteins, Expression, Isolation and Analysis

Degradation of dimethachlon by a newly isolated bacterium Paenarthrobacter sp strain JH-1 relieves its toxicity against Chlorella ellipsoidea

Authors: Mingliang Zhang, Wankui Jiang, Siyuan Gao, Qian Zhu, Zhijian Ke, Mingli Jiang, Jiguo Qiu, Qing Hong

Journal: Environ Res

PubMed ID: 35031339

Doi: 10.1016/j.envres.2022.112706

Products & Services: Gene Synthesis

Circ_HECTD1 regulates cerebral ischemia injury via mechanisms involving the regulation of let-7c-5p/ROCK1 axis

Authors: Qian Guo, Tingting Guo, Yuanyuan Sun, Tianrong Chen

Journal: Neuroreport

PubMed ID: 34874325

Doi: 10.1097/WNR.0000000000001743

Products & Services: Plasmid DNA Preparation

Involvement of β-cyanoalanine synthase (β-CAS) and sulfurtransferase (ST) in cyanide (CN) assimilation in rice seedlings

Authors: Yu-Xi Feng, Cheng-Zhi Li, Yu-Juan Lin, Xiao-Zhang Yu

Journal: Chemosphere

PubMed ID: 35101430

Doi: 10.1016/j.chemosphere.2022.133789

Products & Services: Protein Tools

Crystal Structure Analysis and IgE Epitope Mapping of Allergic Predominant Region in Filamin C, Scy p 9

Authors: Xin-Rong He, Yang Yang, Shuai Kang, Ye-Xin Chen, Pei-Yi Zheng, Gui-Xia Chen, Xiao-Mei Chen, Min-Jie Cao, Tengchuan Jin, Guang-Ming Liu

Journal: J Agric Food Chem

PubMed ID: 35040643

Doi: 10.1021/acs.jafc.1c07922

Products & Services: Peptide Synthesis

Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

Products & Services: Proteins, Expression, Isolation and Analysis

Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells

Authors: Yong Bian, Gang Yin, Gang Wang, Tiantian Liu, Li Liang, Xinyue Yang, Wen Zhang, Decai Tang

Journal: Cell Biol Toxicol

PubMed ID: 35083610

Doi: 10.1007/s10565-021-09681-2

Products & Services: Proteins, Expression, Isolation and Analysis

Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

Products & Services: GenParts™ DNA Fragments

Roles of Close Homologues SigB and SigD in Heat and High Light Acclimation of the Cyanobacterium sp PCC 6803

Authors: Otso Turunen, Satu Koskinen, Juha Kurkela, Outi Karhuvaara, Kaisa Hakkila, Taina Tyystjärvi

Journal: Life (Basel)

PubMed ID: 35207450

Doi: 10.3390/life12020162

Products & Services: GenParts™ DNA Fragments

Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence

Authors: Stefano Perni, Kurt Beam

Journal: J Gen Physiol

PubMed ID: 35089322

Doi: 10.1085/jgp.202113024

Products & Services: Mammalian Expression

CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34981767

Doi: 10.1107/S205979832101216X

Products & Services: Codon Optimization

Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia

Authors: Stefan Hirschberg, Anton Dvorzhak, Seyed M A Rasooli-Nejad, Svilen Angelov, Marieluise Kirchner, Philipp Mertins, Gilla Lättig-Tünnemann, Christoph Harms, Dietmar Schmitz, Rosemarie Grantyn

Journal: Front Cell Neurosci

PubMed ID: 35173582

Doi: 10.3389/fncel.2021.792652

Products & Services: Recombinant Antibody Expression

Journal: Front Cell Neurosci

PubMed ID: 35173582

Doi: 10.3389/fncel.2021.792652

Products & Services: Recombinant Antibody Expression

DNA methylation analysis of ELOVL2 gene using droplet digital PCR for age estimation purposes

Authors: Licínio Manco, Helena Correia Dias

Journal: FORENSIC SCI INT

PubMed ID: 35131731

Doi: 10.1016/j.forsciint.2022.111206

Products & Services: Custom DNA/RNA Oligos

DNA methylation analysis of ELOVL2 gene using droplet digital PCR for age estimation purposes

Authors: Licínio Manco, Helena Correia Dias

Journal: FORENSIC SCI INT

PubMed ID: 35131731

Doi: 10.1016/j.forsciint.2022.111206

Products & Services: Custom DNA/RNA Oligos

CryoEM analysis of small plant biocatalysts at sub-2 Å resolution

Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 34981767

Doi: 10.1107/S205979832101216X

Products & Services: Codon Optimization

Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin

Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng

Journal: Pharmaceutics

PubMed ID: 35057038

Doi: 10.3390/pharmaceutics14010144

Products & Services: Plasmid DNA Preparation

Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin

Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng

Journal: Pharmaceutics

PubMed ID: 35057038

Doi: 10.3390/pharmaceutics14010144

Products & Services: Plasmid DNA Preparation

Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection

Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang

Journal: Environ Sci Technol

PubMed ID: 35049283

Doi: 10.1021/acs.est.1c07172

Products & Services: Proteins, Expression, Isolation and Analysis

Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

Authors: Nathaniel L Miller, Thomas Clark, Rahul Raman, Ram Sasisekharan

Journal: Cell Rep Med

PubMed ID: 35233548

Doi: 10.1016/j.xcrm.2022.100527

Products & Services: Custom Vector Construction

Conditional Alternative Protein Splicing Promoted by Inteins from

Authors: Vaishnavi R Yalala, Abigeal K Lynch, Kenneth V Mills

Journal: Biochemistry

PubMed ID: 35073064

Doi: 10.1021/acs.biochem.1c00788

Products & Services: Plasmid DNA Preparation

Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

Authors: Nathaniel L Miller, Thomas Clark, Rahul Raman, Ram Sasisekharan

Journal: Cell Rep Med

PubMed ID: 35233548

Doi: 10.1016/j.xcrm.2022.100527

Products & Services: Custom Vector Construction

Genome-wide identification and expression profile of YABBY genes in

Authors: Chengru Li, Na Dong, Liming Shen, Meng Lu, Junwen Zhai, Yamei Zhao, Lei Chen, Zhiting Wan, Zhongjian Liu, Hui Ren, Shasha Wu

Journal: PeerJ

PubMed ID: 35036123

Doi: 10.7717/peerj.12558

Products & Services: Protein Tools

Production and application of mouse monoclonal antibodies targeting linear epitopes in pB602L of African swine fever virus

Authors: Pengfei Wang, Chunguo Liu, Shida Wang, Lili Wen, Zhibin Shi, Yue Chi, Ming Wang, Zaisi Liu, Zhenzhao Sun, Lili Wei, Decheng Yang, Xijun He, Jingfei Wang

Journal: Arch Virol

PubMed ID: 34984562

Doi: 10.1007/s00705-021-05335-0

Products & Services: Custom Vector Construction

Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia

Authors: Fangyi Yao, Cui Zhao, Fangmin Zhong, Tingyu Qin, Shuqi Li, Jing Liu, Bo Huang, Xiaozhong Wang

Journal: PeerJ

PubMed ID: 35111390

Doi: 10.7717/peerj.12616

Products & Services: Custom DNA/RNA Oligos

Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia

Authors: Fangyi Yao, Cui Zhao, Fangmin Zhong, Tingyu Qin, Shuqi Li, Jing Liu, Bo Huang, Xiaozhong Wang

Journal: PeerJ

PubMed ID: 35111390

Doi: 10.7717/peerj.12616

Products & Services: Custom DNA/RNA Oligos

The Novel microRNA Rno-miR-686-3p Is Associated with the Ischaemic Penumbra

Authors: Wei Wang, Jin-Pin Li, Jing-Li Liu

Journal: Eur Neurol

PubMed ID: 35100587

Doi: 10.1159/000521491

Products & Services: DNA Sequencing

Self-Assembly of Flagellin into Immunostimulatory Ring-like Nanostructures as an Antigen Delivery System

Authors: Mélanie Côté-Cyr, Ximena Zottig, Laurie Gauthier, Denis Archambault, Steve Bourgault

Journal: ACS Biomater Sci Eng

PubMed ID: 35080372

Doi: 10.1021/acsbiomaterials.1c01332

Products & Services: Gene Synthesis

Role of PG0192 and PG0193 in the modulation of pro-inflammatory cytokines in macrophages in response to Porphyromonas gingivalis

Authors: Hongyan Wang, Wenying Peng, Guangyu Zhang, Muzhou Jiang, Jian Zhao, Xue Zhao, Yaping Pan, Li Lin

Journal: Eur J Oral Sci

PubMed ID: 35049069

Doi: 10.1111/eos.12851

Products & Services: GenParts™ DNA Fragments

Role of PG0192 and PG0193 in the modulation of pro-inflammatory cytokines in macrophages in response to Porphyromonas gingivalis

Authors: Hongyan Wang, Wenying Peng, Guangyu Zhang, Muzhou Jiang, Jian Zhao, Xue Zhao, Yaping Pan, Li Lin

Journal: Eur J Oral Sci

PubMed ID: 35049069

Doi: 10.1111/eos.12851

Products & Services: GenParts™ DNA Fragments

Protocol for structure determination of SARS-CoV-2 main protease at near-physiological-temperature by serial femtosecond crystallography

Authors: Fatma Betul Ertem, Omur Guven, Cengizhan Buyukdag, Oktay Gocenler, Esra Ayan, Busra Yuksel, Mehmet Gul, Gozde Usta, Barıs Cakılkaya, J Austin Johnson, E Han Dao, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Brandon Hayes, Mengning Liang, Mark S Hunter, Alexander Batyuk, Raymond G Sierra, Gihan Ketawala, Sabine Botha, Çağdaş Dağ, Hasan DeMirci

Journal: STAR Protoc

PubMed ID: 35194584

Doi: 10.1016/j.xpro.2022.101158

Products & Services: Proteins, Expression, Isolation and Analysis

Large inter-individual variability of cellular and humoral immunological responses to mRNA-1273 (Moderna) vaccination against SARS-CoV-2 in health care workers

Authors: Alexander Krüttgen, Gerhard Haase, Helga Haefner, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223670

Doi: 10.7774/cevr.2022.11.1.96

CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA

Authors: Simin Chen, Zhaoyu Zhang, Baoxin Zhang, Qing Huang, Yi Liu, Yi Qiu, Xinmiao Long, Minghua Wu, Zuping Zhang

Journal: Int J Biol Sci

PubMed ID: 35002529

Doi: 10.7150/ijbs.66114

Products & Services: Plasmid DNA Preparation

Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue

Authors: Yingzi Tan, Miao Wang, Yijun Chen

Journal: ACS Synth Biol

PubMed ID: 35006674

Doi: 10.1021/acssynbio.1c00578

Products & Services: Gene Synthesis

The Linker Region Promotes Activity and Binding Efficiency of Modular LPMO towards Polymeric Substrate

Authors: Aishwarya Srivastava, Pragya Nagar, Sumit Rathore, Nidhi Adlakha

Journal: Microbiol Spectr

PubMed ID: 35080440

Doi: 10.1128/spectrum.02697-21

Products & Services: Custom DNA/RNA Oligos

Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites

Authors: Bruna Felício Milazzotto Maldonado Porchia, Luana Raposo de Melo Moraes Aps, Ana Carolina Ramos Moreno, Jamile Ramos da Silva, Mariângela de Oliveira Silva, Natiely Silva Sales, Rubens Prince Dos Santos Alves, Clarissa Ribeiro Reily Rocha, Matheus Molina Silva, Karine Bitencourt Rodrigues, Tácita Borges Barros, Roberta Liberato Pagni, Patrícia da Cruz Souza, Mariana de Oliveira Diniz, Luís Carlos de Souza Ferreira

Journal: Int J Biol Sci

PubMed ID: 34975315

Doi: 10.7150/ijbs.56644

Products & Services: Catalog Peptides

Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin

Authors: Favian A Liu, Negar Ardabili, Izaiah Brown, Harmain Rafi, Clarice Cook, Rodanthi Nikopoulou, Arianna Lopez, Shouzhong Zou, Matthew R Hartings, Alexander G Zestos

Journal: J Electrochem Soc

PubMed ID: 35185166

Doi: 10.1149/1945-7111/ac4aae

Products & Services: Catalog Peptides

An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein

Authors: Yahiro Mukai, Masayuki Horie, Shohei Kojima, Junna Kawasaki, Ken Maeda, Keizo Tomonaga

Journal: FEBS Lett

PubMed ID: 35043395

Doi: 10.1002/1873-3468.14290

Products & Services: Recombinant Antibody Expression

Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway

Authors: Veronica Mutti, Federica Bono, Zaira Tomasoni, Leonardo Bontempi, Adele Guglielmi, Silvia Bolognin, Jens C Schwamborn, Cristina Missale, Chiara Fiorentini

Journal: Mol Neurobiol

PubMed ID: 35044626

Doi: 10.1007/s12035-022-02748-z

Products & Services: Gene Synthesis

miR-541-3p Promoted Porcine Reproductive and Respiratory Syndrome Virus 2 (PRRSV-2) Replication by Targeting Interferon Regulatory Factor 7

Authors: Xibao Shi, Yuanhao Yang, Xiaozhuan Zhang, Xiaobo Chang, Jing Chen, Chao Wang, Aiping Wang, Jianhua Wang, Jianru Qin, Xianlong Ye, Wei Jin, Gaiping Zhang

Journal: Viruses

PubMed ID: 35062330

Doi: 10.3390/v14010126

Products & Services: Monoclonal Antibody Services

Expression of phenylalanine ammonia lyases in Synechocystis sp PCC 6803 and subsequent improvements of sustainable production of phenylpropanoids

Authors: Kateryna Kukil, Pia Lindberg

Journal: Microb Cell Fact

PubMed ID: 35012528

Doi: 10.1186/s12934-021-01735-8

Products & Services: Codon Optimization

Targeted deletion of liver-expressed Choriogenin L results in the production of soft eggs and infertility in medaka, Oryzias latipes

Authors: Kenji Murata, Masato Kinoshita

Journal: Zoological Lett

PubMed ID: 34983666

Doi: 10.1186/s40851-021-00185-9

Products & Services: Catalog Peptides

Anion binding to a cationic europium(III) probe enables the first real-time assay of heparan sulfotransferase activity

Authors: Simon Wheeler, Colum Breen, Yong Li, Sarah H Hewitt, Erin Robertson, Edwin A Yates, Igor L Barsukov, David G Fernig, Stephen J Butler

Journal: Org Biomol Chem

PubMed ID: 34951618

Doi: 10.1039/d1ob02071d

Products & Services: Proteins, Expression, Isolation and Analysis

Multiplex genome editing of mammalian cells for producing recombinant heparin

Authors: Bryan E Thacker, Kristen J Thorne, Colin Cartwright, Jeeyoung Park, Kimberly Glass, Annie Chea, Benjamin P Kellman, Nathan E Lewis, Zhenping Wang, Anna Di Nardo, Susan T Sharfstein, Walter Jeske, Jeanine Walenga, John Hogwood, Elaine Gray, Barbara Mulloy, Jeffrey D Esko, Charles A Glass

Journal: Metab Eng

PubMed ID: 35038554

Doi: 10.1016/j.ymben.2022.01.002

Products & Services: Custom Vector Construction

Multiplex genome editing of mammalian cells for producing recombinant heparin

Journal: Metab Eng

PubMed ID: 35038554

Doi: 10.1016/j.ymben.2022.01.002

Products & Services: Custom Vector Construction

Genome-wide analysis and transcriptional reprogrammings of MYB superfamily revealed positive insights into abiotic stress responses and anthocyanin accumulation in Carthamus tinctorius L

Authors: Yingqi Hong, Naveed Ahmad, Jianyi Zhang, Yanxi Lv, Xinyue Zhang, Xintong Ma, Liu Xiuming, Yao Na

Journal: Mol Genet Genomics

PubMed ID: 34978004

Doi: 10.1007/s00438-021-01839-1

Products & Services: Protein Tools

Knockdown of DPP4 promotes the proliferation and the activation of the CREB/aromatase pathway in ovarian granulosa cells

Authors: Lina Lin, Liman Wang

Journal: Mol Med Rep

PubMed ID: 35014677

Doi: 10.3892/mmr.2022.12589

Products & Services: Gene Synthesis

Highly efficient A-to-G base editing by ABE8.17 in rabbits

Authors: Ding Zhao , Yuqiang Qian , Jinze Li , Zhanjun Li , Liangxue Lai

Journal: Mol Ther Nucleic Acids .

PubMed ID: 35282412

Doi: 10.1016/j.omtn.2022.01.019

Products & Services: Gene Synthesis

Optimization of Protoplast Isolation and Transformation for a Pilot Study of Genome Editing in Peanut by Targeting the Allergen Gene

Authors: Sudip Biswas, Nancy J Wahl, Michael J Thomson, John M Cason, Bill F McCutchen, Endang M Septiningsih

Journal: Int J Mol Sci

PubMed ID: 35055026

Doi: 10.3390/ijms23020837

Products & Services: Synthetic sgRNA and crRNA Service

Performance of the cobas® HBV RNA automated investigational assay for the detection and quantification of circulating HBV RNA in chronic HBV patients

Authors: Caroline Scholtès, Aaron T Hamilton, Marie-Laure Plissonnier, Caroline Charre, Beth Scott, Ling Wang, Françoise Berby, Janine French, Barbara Testoni, Alan Blair, Miroslava Subic, Matthias Hoppler, Andreas Lankenau, Andreas Grubenmann, Massimo Levrero, Marintha L Heil, Fabien Zoulim

Journal: J Clin Virol

PubMed ID: 35427860

Doi: 10.1016/j.jcv.2022.105150

Products & Services: Molecular Biology Reagents

Reactivity of DENV-positive sera against recombinant envelope proteins produced in bacteria and eukaryotic cells

Authors: Higo Fernando Santos Souza, Arthur Baruel Zaneti, Bianca da Silva Almeida, Jéssica Amaral Martinho, Márcio Massao Yamamoto, Daniela Santoro Rosa, Renata Denzegrini Slhessarenko, Silvia Beatriz Boscardin

Journal: Immunol Res

PubMed ID: 36192522

Doi: 10.1007/s12026-022-09326-4

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered bacterial host for genetic encoding of physiologically stable protein nitration

Authors: Nikolaj G Koch, Tobias Baumann, Jessica H Nickling, Anna Dziegielewski, Nediljko Budisa

Journal: Front Mol Biosci

PubMed ID: 36353730

Doi: 10.3389/fmolb.2022.992748

Products & Services: Gene Synthesis

Intra-amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses

Authors: Xiaowei Wei, Wei Ma, Hui Gu, Dan Liu, Wenting Luo, Songying Cao, Shanshan Jia, Tianchu Huang, Yiwen He, Yuzuo Bai, Weilin Wang, Zhengwei Yuan

Journal: Cell Prolif

PubMed ID: 36266504

Doi: 10.1111/cpr.13354

Products & Services: Gene Synthesis

Tongxinluo prevents chronic obstructive pulmonary disease complicated with atherosclerosis by inhibiting ferroptosis and protecting against pulmonary microvascular barrier dysfunction

Authors: Yafen Wang, Xiangnan Kuang, Yujie Yin , Ningxin Han, Liping Chang, Hongtao Wang, Yunlong Hou, Huixin Li, Zhen Li , Yi Liu, Yuanjie Hao , Yaru Wei, Xiaoqi Wang, Zhenhua Jia

Journal: Biomed Pharmacother

PubMed ID: 34740097

Doi: 10.1016/j.biopha.2021.112367

Products & Services: Proteins, Expression, Isolation and Analysis

CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy

Authors: Dan Wang, Ling Chen, Chengbi Li, Quanxin Long, Qing Yang, Ailong Huang, Hua Tang

Journal: J Nanobiotechnology

PubMed ID: 34991617

Doi: 10.1186/s12951-021-01233-4

Products & Services: GenCrispr Cas9 Genome Editing

Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase

Authors: Chia Wei Hsu, Mark L Sowers, Tuvshintugs Baljinnyam, Jason L Herring, Linda C Hackfeld, Hui Tang, Kangling Zhang, Lawrence C Sowers

Journal: J Biol Chem

PubMed ID: 35085553

Doi: 10.1016/j.jbc.2022.101638

Products & Services: Gene Synthesis

Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection

Authors: Bojie Xu , Ruicheng Yang , Bo Yang , Liang Li , Jiaqi Chen , Jiyang Fu , Xinyi Qu , Dong Huo , Chen Tan , Huanchun Chen , Zhong Peng , Xiangru Wang

Journal: Mol Brain

PubMed ID: 34980188

Doi: 10.1186/s13041-021-00890-8

Products & Services: ORF cDNA Clones/MolecularCloud

SARS-CoV-2 S Protein Subunit 1 Elicits Ca2+ Influx – Dependent Ca2+ Signals in Pancreatic Stellate Cells and Macrophages In Situ

Authors: Julia V Gerasimenko , Ole H Petersen , Oleg V Gerasimenko

Journal: Function (Oxf)

Doi: 10.1093/function/zqac002

Products & Services: Recombinant Proteins

Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus

Authors: Bryce P Johnson , Vikas Kumar , Erin M Scull , Leonard M Thomas , Christina R Bourne , Shanteri Singh

Journal: ACS Chem Biol

PubMed ID: 34905349

Doi: 10.1021/acschembio.1c00655

Products & Services: Gene Synthesis

Efficient Amber Suppression Ribosomal Skipping for Synthesis of Photoconditional Nanobodies

Authors: Eike F Joest, Christian Winter, Joshua S Wesalo, Alexander Deiters, Robert Tampé

Journal: ACS Synth Biol

PubMed ID: 35060375

Doi: 10.1021/acssynbio.1c00471

Products & Services: Plasmid DNA Preparation

Protein Phosphatase 2A Deficiency in Macrophages Increases Foam Cell Formation and Accelerates Atherosclerotic Lesion Development

Authors: Rui Li, Chao Zhang, Fei Xie, Xianming Zhou, Xingjian Hu, Jiawei Shi, Xinling Du, Zhiyong Lin, Nianguo Dong

Journal: Front Cardiovasc Med

PubMed ID: 35118139

Doi: 10.3389/fcvm.2021.745009

Products & Services: Proteins, Expression, Isolation and Analysis

Synthesis of broad-specificity activity-based probes for -β-mannosidases

Authors: Nicholas G S McGregor, Chi-Lin Kuo, Thomas J M Beenakker, Chun-Sing Wong, Wendy A Offen, Zachary Armstrong, Bogdan I Florea, Jeroen D C Codée, Herman S Overkleeft, Johannes M F G Aerts, Gideon J Davies

Journal: Org Biomol Chem

PubMed ID: 35015006

Doi: 10.1039/d1ob02287c

Products & Services: Proteins, Expression, Isolation and Analysis

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system

Authors: Yue Wu, Zhenling Cui, Yen-Hua Huang, Simon J de Veer, Andrey V Aralov, Zhong Guo, Shayli V Moradi, Alexandra O Hinton, Jennifer R Deuis, Shaodong Guo, Kai-En Chen, Brett M Collins, Irina Vetter, Volker Herzig, Alun Jones, Matthew A Cooper, Glenn F King, David J Craik, Kirill Alexandrov, Sergey Mureev

Journal: Nat Commun

PubMed ID: 35017494

Doi: 10.1038/s41467-021-27854-9

Products & Services: DNA Sequencing

Dietary Isoflavones Alter Gut Microbiota and Lipopolysaccharide Biosynthesis to Reduce Inflammation

Authors: Sudeep Ghimire, Nicole M Cady, Peter Lehman, Stephanie R Peterson, Shailesh K Shahi, Faraz Rashid, Shailendra Giri, Ashutosh K Mangalam

Journal: Gut Microbes

PubMed ID: 36179318

Doi: 10.1080/19490976.2022.2127446

Products & Services: Endotoxin Detection & Removal System

Identification of sequence-specific promoters driving polycistronic transcription initiation by RNA polymerase II in trypanosomes

Authors: Carlos Cordon-Obras, Claudia Gomez-Liñan, Sara Torres-Rusillo, Isabel Vidal-Cobo, Diana Lopez-Farfan, Alicia Barroso-Del Jesus, Domingo Rojas-Barros, Mark Carrington, Miguel Navarro

Journal: Cell Rep

PubMed ID: 35021094

Doi: 10.1016/j.celrep.2021.110221

Products & Services: GenParts™ DNA Fragments

FACI Is a Novel CREB-H-Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity

Authors: Yun Cheng, Xiao-Zhuo Kang, Tao Cheng, Zi-Wei Ye, George L Tipoe, Cheng-Han Yu, Chi-Ming Wong, Baohua Liu, Chi-Ping Chan, Dong-Yan Jin

Journal: Cell Mol Gastroenterol Hepatol

PubMed ID: 35093589

Doi: 10.1016/j.jcmgh.2022.01.017

Products & Services: Stable Cell Lines

The Impact of Tyrosine Iodination on the Aggregation and Cleavage Kinetics of MMP-9-Responsive Peptide Sequences

Authors: Douglas S MacPherson, Scott A McPhee, Brian M Zeglis, Rein V Ulijn

Journal: ACS Biomater Sci Eng

PubMed ID: 35050574

Doi: 10.1021/acsbiomaterials.1c01488

Products & Services: Catalog Peptides

Novel Neutralizing Epitope of PEDV S1 Protein Identified by IgM Monoclonal Antibody

Authors: Techit Thavorasak, Monrat Chulanetra, Kittirat Glab-Ampai, Karsidete Teeranitayatarn, Thaweesak Songserm, Rungrueang Yodsheewan, Nawannaporn Sae-Lim, Porntippa Lekcharoensuk, Nitat Sookrung, Wanpen Chaicumpa

Journal: Viruses

PubMed ID: 35062329

Doi: 10.3390/v14010125

Products & Services: Catalog Peptides

Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies

Authors: Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell Szabo, Mathew Blurton-Jones, David H Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G Agadjanyan

Journal: npj Vaccines

PubMed ID: 35013319

Doi: 10.1038/s41541-021-00424-2

Products & Services: Gene Synthesis

Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation

Authors: Florian J Raabe, Marius Stephan, Jan Benedikt Waldeck, Verena Huber, Damianos Demetriou, Nirmal Kannaiyan, Sabrina Galinski, Laura V Glaser, Michael C Wehr, Michael J Ziller, Andrea Schmitt, Peter Falkai, Moritz J Rossner

Journal: Cells

PubMed ID: 35053357

Doi: 10.3390/cells11020241

Products & Services: Plasmid DNA Preparation

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease

Authors: Yun Yang, Victor Tapias, Diana Acosta, Hui Xu, Huanlian Chen, Ruchika Bhawal, Elizabeth T Anderson, Elena Ivanova, Hening Lin, Botir T Sagdullaev, Jianer Chen, William L Klein, Kirsten L Viola, Sam Gandy, Vahram Haroutunian, M Flint Beal, David Eliezer, Sheng Zhang, Gary E Gibson

Journal: Nat Commun

PubMed ID: 35013160

Doi: 10.1038/s41467-021-27572-2

Products & Services: Catalog Peptides

Shoc2 recognizes bacterial flagellin and mediates antibacterial Erk/Stat signaling in an invertebrate

Authors: Bao-Rui Zhao, Xin-Xin Wang, Xian-Wei Wang

Journal: PLoS Pathog

PubMed ID: 35073369

Doi: 10.1371/journal.ppat.1010253

Products & Services: Proteins, Expression, Isolation and Analysis

The temporal gene expression profiles of calcium and phosphorus transporters in Hy-Line Brown layers

Authors: Xiaojuan Wang, Peng Li, Jingpeng Zhao, Hongchao Jiao, Hai Lin

Journal: Poult Sci

PubMed ID: 35202896

Doi: 10.1016/j.psj.2022.101736

Products & Services: Catalog Antibody

SARS-CoV-2 NSP13 Inhibits Type I IFN Production by Degradation of TBK1 via p62-Dependent Selective Autophagy

Authors: Chao Sui, Tongyang Xiao, Shengyuan Zhang, Hongxiang Zeng, Yi Zheng, Bingyu Liu, Gang Xu, Chengjiang Gao, Zheng Zhang

Journal: J Immunol

PubMed ID: 34996837

Doi: 10.4049/jimmunol.2100684

Products & Services: Catalog Antibody

Silencing of circCDC14A prevents cerebral ischemia-reperfusion injury via miR-23a-3p/CXCL12 axis

Authors: Huiyi Huo, Chao Hu, Yongxue Lu, Jinyu Zhou, Zhiguang Mai

Journal: J Biochem Mol Toxicol

PubMed ID: 34978116

Doi: 10.1002/jbt.22982

Products & Services: Gene Synthesis

Plant-Based Vaccines in Combat against Coronavirus Diseases

Authors: Benita Ortega-Berlanga, Tomasz Pniewski

Journal: Vaccines (Basel)

PubMed ID: 35214597

Doi: 10.3390/vaccines10020138

Products & Services: Proteins, Expression, Isolation and Analysis

NMR Detection and Structural Modeling of the Ethylene Receptor LeETR2 from Tomato

Authors: Shukun Wei, Yaqing Yang, Yuan Yuan, Lingyu Du, Hongjuan Xue, Bo OuYang

Journal: Membranes (Basel)

PubMed ID: 35207029

Doi: 10.3390/membranes12020107

Products & Services: Custom DNA/RNA Oligos

Genome-Wide Identification and Expression Profiles of Genes in L

Authors: Meng Lu, Xiang-Xiao Meng, Yi-Ming Zhang, Xue-Wen Zhu, Jun Li, Wei-Qiang Chen, Hui-Hua Wan, Si-Fan Wang, Xue Cao, Wei Sun, Yao-Lei Mi, Jun-Wen Zhai

Journal: Cannabis Cannabinoid Res

PubMed ID: 35020417

Doi: 10.1089/can.2021.0153

Products & Services: Protein Tools

Hemagglutinin-based DNA vaccines containing trimeric self-assembling nanoparticles confer protection against influenza

Authors: Yongbo Qiao, Shenghui Jin, Jiaojiao Nie, Yaotian Chang, Bo Wang, Shanshan Guan, Qinghan Li, Yuhua Shi, Wei Kong, Yaming Shan

Journal: J Leukoc Biol

PubMed ID: 35040188

Doi: 10.1002/JLB.6A1021-535R

Products & Services: Mammalian Expression

Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase

Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek

Journal: Cells

PubMed ID: 35011726

Doi: 10.3390/cells11010165

Products & Services: Custom Vector Construction

Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase

Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek

Journal: Cells

PubMed ID: 35011726

Doi: 10.3390/cells11010165

Products & Services: Custom Vector Construction

Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants

Authors: Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran

Journal: Viruses

PubMed ID: 35215823

Doi: 10.3390/v14020230

Products & Services: Recombinant Proteins

theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions

Authors: Teresa Lopes Gomes, Virgínia de Oliveira-Marques, Richard John Hampson, António Jacinto, Luciana Vieira de Moraes, Rui Gonçalo Martinho

Journal: Front Pharmacol

PubMed ID: 35069190

Doi: 10.3389/fphar.2021.752787

Products & Services: Custom Vector Construction

Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model

Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto

Journal: Toxics

PubMed ID: 35051082

Doi: 10.3390/toxics10010040

Products & Services: Endotoxin Detection & Removal System

Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model

Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto

Journal: Toxics

PubMed ID: 35051082

Doi: 10.3390/toxics10010040

Products & Services: Endotoxin Detection & Removal System

Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR

Authors: Zhenyu Wang, Jing Chen, Qiong-Ge Zhang, Kai Huang, Dan Ma, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 35085949

Doi: 10.1016/j.vetmic.2022.109354

Products & Services: Catalog Antibody

lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway

Authors: Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang

Journal: Mediators Inflamm

PubMed ID: 35125964

Doi: 10.1155/2022/6979117

Products & Services: Custom DNA/RNA Oligos

Targeted deletion of liver-expressed Choriogenin L results in the production of soft eggs and infertility in medaka, Oryzias latipes

Authors: Kenji Murata, Masato Kinoshita

Journal: Zoological Lett

PubMed ID: 34983666

Doi: 10.1186/s40851-021-00185-9

Products & Services: Catalog Peptides

Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites

Journal: Int J Biol Sci

PubMed ID: 34975315

Doi: 10.7150/ijbs.56644

Products & Services: Catalog Peptides

Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice

Authors: Yi Zhang, Mufan Ji, Zhenyang Gu, Wenlong Pei, Jun Zhu, Qian Wu, Lei Li, Zhan Zhang

Journal: Toxicology

PubMed ID: 34979169

Doi: 10.1016/j.tox.2021.153088

Products & Services: Custom DNA/RNA Oligos

Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations

Authors: Anju Jaiswal, D Dash, Rashmi Singh

Journal: Toxicol Appl Pharmacol

PubMed ID: 34998855

Doi: 10.1016/j.taap.2021.115861

Products & Services: Endotoxin Detection & Removal System

Directed Evolution of Replication-Competent Double-Stranded DNA Bacteriophage toward New Host Specificity

Authors: Jing Liang, Huibin Zhang, Yee Ling Tan, Huimin Zhao, Ee Lui Ang

Journal: ACS Synth Biol

PubMed ID: 35090114

Doi: 10.1021/acssynbio.1c00319

Products & Services: GenParts™ DNA Fragments

Ethylene response factor MdERF4 and histone deacetylase MdHDA19 suppress apple fruit ripening through histone deacetylation of ripening related genes

Authors: Yanan Hu, Zhenyun Han, Ting Wang, Hua Li, Qiqi Li, Shuai Wang, Ji Tian, Yi Wang, Xinzhong Zhang, Xuefeng Xu, Zhenhai Han, Peitao Lü, Ting Wu

Journal: Plant Physiol

PubMed ID: 35088866

Doi: 10.1093/plphys/kiac016

Products & Services: Catalog Antibody

Speed dating for enzymes! Finding the perfect phosphopantetheinyl transferase partner for your polyketide synthase

Authors: Tobias Bruun Pedersen, Mikkel Rank Nielsen, Sebastian Birkedal Kristensen, Eva Mie Lang Spedtsberg, Trine Sørensen, Celine Petersen, Jens Muff, Teis Esben Sondergaard, Kåre Lehmann Nielsen, Reinhard Wimmer, Donald Max Gardiner, Jens Laurids Sørensen

Journal: Microb Cell Fact

PubMed ID: 35012550

Doi: 10.1186/s12934-021-01734-9

Products & Services: Codon Optimization

A biomimetic enzyme-linked immunosorbent assay (BELISA) for the analysis of gonadorelin by using molecularly imprinted polymer-coated microplates

Authors: Francesca Torrini, Laura Caponi, Andrea Bertolini, Pasquale Palladino, Francesca Cipolli, Alessandro Saba, Aldo Paolicchi, Simona Scarano, Maria Minunni

Journal: Anal Bioanal Chem

PubMed ID: 35028691

Doi: 10.1007/s00216-021-03867-7

Products & Services: ORF cDNA Clones/MolecularCloud

Initiator-Directed Transcription: Fission Yeast Nmtl Initiator Directs Preinitiation Complex Formation and Transcriptional Initiation

Authors: Diego A Rojas, Fabiola Urbina, Lucía Valenzuela-Pérez, Lorenzo Leiva, Vicente J Miralles, Edio Maldonado

Journal: Genes (Basel)

PubMed ID: 35205301

Doi: 10.3390/genes13020256

Products & Services: Gene Synthesis