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FACI Is a Novel CREB-H-Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity

Authors: Yun Cheng, Xiao-Zhuo Kang, Tao Cheng, Zi-Wei Ye, George L Tipoe, Cheng-Han Yu, Chi-Ming Wong, Baohua Liu, Chi-Ping Chan, Dong-Yan Jin

Journal: Cell Mol Gastroenterol Hepatol

PubMed ID: 35093589

Doi: 10.1016/j.jcmgh.2022.01.017

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The Impact of Tyrosine Iodination on the Aggregation and Cleavage Kinetics of MMP-9-Responsive Peptide Sequences

Authors: Douglas S MacPherson, Scott A McPhee, Brian M Zeglis, Rein V Ulijn

Journal: ACS Biomater Sci Eng

PubMed ID: 35050574

Doi: 10.1021/acsbiomaterials.1c01488

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Novel Neutralizing Epitope of PEDV S1 Protein Identified by IgM Monoclonal Antibody

Authors: Techit Thavorasak, Monrat Chulanetra, Kittirat Glab-Ampai, Karsidete Teeranitayatarn, Thaweesak Songserm, Rungrueang Yodsheewan, Nawannaporn Sae-Lim, Porntippa Lekcharoensuk, Nitat Sookrung, Wanpen Chaicumpa

Journal: Viruses

PubMed ID: 35062329

Doi: 10.3390/v14010125

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Augmented ERAD (ER-associated degradation) activity in chondrocytes is necessary for cartilage development and maintenance

Authors: Hyo Jung Sim, Chanmi Cho, Ha Eun Kim, Ju Yeon Hong, Eun Kyung Song, Keun Yeong Kwon, Dong Gil Jang, Seok-Jung Kim, Hyun-Shik Lee, Changwook Lee, Taejoon Kwon, Siyoung Yang, Tae Joo Park

Journal: Sci Adv

PubMed ID: 35061535

Doi: 10.1126/sciadv.abl4222

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Cytokines in the Immune Microenvironment Change the Glycosylation of IgG by Regulating Intracellular Glycosyltransferases

Authors: Yedi Cao, Zhijing Song, Zhendong Guo, Xue Zhao, Yan Gong, Keli Zhao, Chenxue Qu, Youyuan Huang, Yan Li, Ying Gao, Junqing Zhang, Xiaohui Guo

Journal: Front Immunol

PubMed ID: 35140700

Doi: 10.3389/fimmu.2021.724379

Products & Services: Proteins, Expression, Isolation and Analysis

Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment

Authors: Le Thi My Le, James Robert Thompson, Phuoc Xuan Dang, Janarjan Bhandari, Amer Alam

Journal: Commun Biol

PubMed ID: 35013584

Doi: 10.1038/s42003-021-02970-w

Products & Services: Proteins, Expression, Isolation and Analysis

Shoc2 recognizes bacterial flagellin and mediates antibacterial Erk/Stat signaling in an invertebrate

Authors: Bao-Rui Zhao, Xin-Xin Wang, Xian-Wei Wang

Journal: PLoS Pathog

PubMed ID: 35073369

Doi: 10.1371/journal.ppat.1010253

Products & Services: Proteins, Expression, Isolation and Analysis

Engineered human antibodies for the opsonization and killing of

Authors: Xinhai Chen, Olaf Schneewind, Dominique Missiakas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35058363

Doi: 10.1073/pnas.2114478119

Products & Services: Proteins, Expression, Isolation and Analysis

Porcine TRIM21 Enhances Porcine Circovirus 2 Infection and Host Immune Responses, But Inhibits Apoptosis of PCV2-Infected Cells

Authors: Lin Yang, Xiaohua Liu, Liying Zhang, Xue Li, Xinwei Zhang, Guoyu Niu, Weilong Ji, Si Chen, Hongsheng Ouyang, Linzhu Ren

Journal: Viruses

PubMed ID: 35062360

Doi: 10.3390/v14010156

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Targeted gene silencing in the nervous system with CRISPR-Cas13

Authors: Jackson E Powell, Colin K W Lim, Ramya Krishnan, Tristan X McCallister, Christian Saporito-Magriña, Maria A Zeballos, Garrett D McPheron, Thomas Gaj

Journal: Sci Adv

PubMed ID: 35044815

Doi: 10.1126/sciadv.abk2485

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Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus

Authors: Liqi Liu, Zi Li, Jianfang Zhou, Jia Liu, Xiyan Li, Weijuan Huang, Ning Xiao, Dayan Wang

Journal: Influenza Other Respir Viruses

PubMed ID: 35037399

Doi: 10.1111/irv.12954

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Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer

Authors: Junko Matsuzaki, Shashikant Lele, Kunle Odunsi, Takemasa Tsuji

Journal: Oncoimmunology

PubMed ID: 35003898

Doi: 10.1080/2162402X.2021.2020983

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Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer

Authors: Junko Matsuzaki, Shashikant Lele, Kunle Odunsi, Takemasa Tsuji

Journal: Oncoimmunology

PubMed ID: 35003898

Doi: 10.1080/2162402X.2021.2020983

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The H, N and C resonance assignments of the low-complexity domain from the oncogenic fusion protein EWS-FLI1

Authors: Courtney N Johnson, Xiaoping Xu, Stephen P Holloway, David S Libich

Journal: Biomol NMR Assign

PubMed ID: 34994941

Doi: 10.1007/s12104-021-10061-4

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Interleukin 21 Receptor Affects Adipogenesis of Human Adipose-Derived Stem/Stromal Cells

Authors: Bruna Cristina Falavinha, María Julia Barisón, Carmen Lúcia Kuniyoshi Rebelatto, Bruna Hilzendeger Marcon, Alessandra de Melo Aguiar, Evelin Brandão da Silva, Marco Augusto Stimamiglio, Patrícia Shigunov

Journal: Stem Cells Int

PubMed ID: 35047041

Doi: 10.1155/2022/4930932

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miR-223 in exosomes from bone marrow mesenchymal stem cells ameliorates rheumatoid arthritis via downregulation of NLRP3 expression in macrophages

Authors: Ying Huang, Daomin Lu, Wukai Ma, Jun Liu, Qiaoyi Ning, Fang Tang, Long Li

Journal: Mol Immunol

PubMed ID: 35042119

Doi: 10.1016/j.molimm.2022.01.002

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Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles

Authors: Yueyue Duan, Liyan Cao, Cong Yuan, Xuepeng Suo, Xiangyu Kong, Yulong Gao, Xiangtong Li, Haixue Zheng, Xiaomei Wang, Qi Wang

Journal: MBio

PubMed ID: 35038897

Doi: 10.1128/mbio.03287-21

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An Active Peptide-Based Packaging System to Improve the Freshness and Safety of Fish Products: A Case Study

Authors: Rosa Luisa Ambrosio, Marta Gogliettino, Bruna Agrillo, Yolande T R Proroga, Marco Balestrieri, Lorena Gratino, Daniela Cristiano, Gianna Palmieri, Aniello Anastasio

Journal: Foods

PubMed ID: 35159493

Doi: 10.3390/foods11030338

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Targeted deletion of liver-expressed Choriogenin L results in the production of soft eggs and infertility in medaka, Oryzias latipes

Authors: Kenji Murata, Masato Kinoshita

Journal: Zoological Lett

PubMed ID: 34983666

Doi: 10.1186/s40851-021-00185-9

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Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours

Authors: Xiaoyu Yu, Ying Bai, Bing Han, Minzi Ju, Tianci Tang, Ling Shen, Mingyue Li, Li Yang, Zhao Zhang, Guoku Hu, Jie Chao, Yuan Zhang, Honghong Yao

Journal: J Extracell Vesicles

PubMed ID: 35029057

Doi: 10.1002/jev2.12185

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miR-541-3p Promoted Porcine Reproductive and Respiratory Syndrome Virus 2 (PRRSV-2) Replication by Targeting Interferon Regulatory Factor 7

Authors: Xibao Shi, Yuanhao Yang, Xiaozhuan Zhang, Xiaobo Chang, Jing Chen, Chao Wang, Aiping Wang, Jianhua Wang, Jianru Qin, Xianlong Ye, Wei Jin, Gaiping Zhang

Journal: Viruses

PubMed ID: 35062330

Doi: 10.3390/v14010126

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Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations

Authors: Anju Jaiswal, D Dash, Rashmi Singh

Journal: Toxicol Appl Pharmacol

PubMed ID: 34998855

Doi: 10.1016/j.taap.2021.115861

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Deletion of Specific Conserved Motifs from the N-Terminal Domain of B-Crystallin Results in the Activation of Chaperone Functions

Authors: Sundararajan Mahalingam Goutham Shankar, Brian P. Mooney, Kamal Singh, Puttur Santhoshkumar, and Krishna K. Sharma

Journal: International Journal of Molecular Sciences

Doi: 10.3390/ijms23031099

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Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies

Authors: Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell Szabo, Mathew Blurton-Jones, David H Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G Agadjanyan

Journal: npj Vaccines

PubMed ID: 35013319

Doi: 10.1038/s41541-021-00424-2

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Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation

Authors: Florian J Raabe, Marius Stephan, Jan Benedikt Waldeck, Verena Huber, Damianos Demetriou, Nirmal Kannaiyan, Sabrina Galinski, Laura V Glaser, Michael C Wehr, Michael J Ziller, Andrea Schmitt, Peter Falkai, Moritz J Rossner

Journal: Cells

PubMed ID: 35053357

Doi: 10.3390/cells11020241

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Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease

Authors: Yun Yang, Victor Tapias, Diana Acosta, Hui Xu, Huanlian Chen, Ruchika Bhawal, Elizabeth T Anderson, Elena Ivanova, Hening Lin, Botir T Sagdullaev, Jianer Chen, William L Klein, Kirsten L Viola, Sam Gandy, Vahram Haroutunian, M Flint Beal, David Eliezer, Sheng Zhang, Gary E Gibson

Journal: Nat Commun

PubMed ID: 35013160

Doi: 10.1038/s41467-021-27572-2

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Authors: Xiaohui Yuan, Han Xue, Xiaomeng Xu, Xinan Jiao, Zhiming Pan, Yunzeng Zhang

Journal: Gut Pathog

PubMed ID: 35078518

Doi: 10.1186/s13099-022-00480-6

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T cell responses to SARS-CoV-2 spike cross-recognize Omicron

Authors: Roanne Keeton, Marius B Tincho, Amkele Ngomti, Richard Baguma, Ntombi Benede, Akiko Suzuki, Khadija Khan, Sandile Cele, Mallory Bernstein, Farina Karim, Sharon V Madzorera, Thandeka Moyo-Gwete, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Daniel Mutithu, Olukayode Aremu, Cari Stek, Elsa du Bruyn, Mieke A Van Der Mescht, Zelda de Beer, Talita R de Villiers, Annie Bodenstein, Gretha van den Berg, Adriano Mendes, Amy Strydom, Marietjie Venter, Jennifer Giandhari, Yeshnee Naidoo, Sureshnee Pillay, Houriiyah Tegally, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Robert J Wilkinson, Tulio de Oliveira, Linda-Gail Bekker, Glenda Gray, Veronica Ueckermann, Theresa Rossouw, Michael T Boswell, Jinal N Bhiman, Penny L Moore, Alex Sigal, Ntobeko A B Ntusi, Wendy A Burgers, Catherine Riou

Journal: Nature

PubMed ID: 35102311

Doi: 10.1038/s41586-022-04460-3

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Inhibitory effects of specific combination of natural compounds against SARS-CoV-2 and its Alpha, Beta, Gamma, Delta, Kappa, and Mu variants

Authors: Anna Goc, Aleksandra Niedzwiecki, Vadim Ivanov, Svetlana Ivanova, Matthias Rath

Journal: Eur J Microbiol Immunol (Bp)

PubMed ID: 35060921

Doi: 10.1556/1886.2021.00022

Products & Services: Proteins, Expression, Isolation and Analysis

The temporal gene expression profiles of calcium and phosphorus transporters in Hy-Line Brown layers

Authors: Xiaojuan Wang, Peng Li, Jingpeng Zhao, Hongchao Jiao, Hai Lin

Journal: Poult Sci

PubMed ID: 35202896

Doi: 10.1016/j.psj.2022.101736

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High cell surface expression and peptide binding affinity of HLA-DQA1*05:03, a susceptible allele of neuromyelitis optica spectrum disorders (NMOSD)

Authors: Shohei Beppu, Makoto Kinoshita, Jan Wilamowski, Tadahiro Suenaga, Yoshiaki Yasumizu, Kotaro Ogawa, Teruyuki Ishikura, Satoru Tada, Toru Koda, Hisashi Murata, Naoyuki Shiraishi, Yasuko Sugiyama, Keigo Kihara, Tomoyuki Sugimoto, Hisashi Arase, Daron M Standley, Tatsusada Okuno, Hideki Mochizuki

Journal: Sci Rep

PubMed ID: 34997058

Doi: 10.1038/s41598-021-04074-1

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SARS-CoV-2 NSP13 Inhibits Type I IFN Production by Degradation of TBK1 via p62-Dependent Selective Autophagy

Authors: Chao Sui, Tongyang Xiao, Shengyuan Zhang, Hongxiang Zeng, Yi Zheng, Bingyu Liu, Gang Xu, Chengjiang Gao, Zheng Zhang

Journal: J Immunol

PubMed ID: 34996837

Doi: 10.4049/jimmunol.2100684

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Kinetics and persistence of cellular and humoral immune responses to SARS-CoV-2 vaccine in healthcare workers with or without prior COVID-19

Authors: Mihaela Chivu-Economescu, Coralia Bleotu, Camelia Grancea, Daniela Chiriac, Anca Botezatu, Iulia V Iancu, Ioana Pitica, Laura G Necula, Ana Neagu, Lilia Matei, Denisa Dragu, Camelia Sultana, Elena L Radu, Alina Nastasie, Oana Voicu, Marius Ataman, Saviana Nedeianu, Cristina Mambet, Carmen C Diaconu, Simona Maria Ruta

Journal: J Cell Mol Med

PubMed ID: 35043552

Doi: 10.1111/jcmm.17186

Double nicking by RNA-directed Cascade-nCas3 for high-efficiency large-scale genome engineering

Authors: Yile Hao, Qinhua Wang, Jie Li, Shihui Yang, Yanli Zheng, Wenfang Peng

Journal: Open Biol

PubMed ID: 35016549

Doi: 10.1098/rsob.210241

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Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles

Authors: Charles A Specht, E Jane Homan, Chrono K Lee, Zhongming Mou, Christina L Gomez, Maureen M Hester, Ambily Abraham, Florentina Rus, Gary R Ostroff, Stuart M Levitz

Journal: MBio

PubMed ID: 35089095

Doi: 10.1128/mbio.03367-21

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Mitochondrial Dysfunction Associates With Acute T Lymphocytopenia and Impaired Functionality in COVID-19 Patients

Authors: Yufei Mo, Kelvin Kai-Wang To, Runhong Zhou, Li Liu, Tianyu Cao, Haode Huang, Zhenglong Du, Chun Yu Hubert Lim, Lok-Yan Yim, Tsz-Yat Luk, Jacky Man-Chun Chan, Thomas Shiu-Hong Chik, Daphne Pui-Ling Lau, Owen Tak-Yin Tsang, Anthony Raymond Tam, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Zhiwei Chen

Journal: Front Immunol

PubMed ID: 35095881

Doi: 10.3389/fimmu.2021.799896

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Silencing of circCDC14A prevents cerebral ischemia-reperfusion injury via miR-23a-3p/CXCL12 axis

Authors: Huiyi Huo, Chao Hu, Yongxue Lu, Jinyu Zhou, Zhiguang Mai

Journal: J Biochem Mol Toxicol

PubMed ID: 34978116

Doi: 10.1002/jbt.22982

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Inhibition of microRNA-448 suppresses CD4 T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus

Authors: Jing Zhang, Yun Guo, Yue Sun, Lihua Chang, Xiaofei Wang

Journal: Biochem Biophys Res Commun

PubMed ID: 35121374

Doi: 10.1016/j.bbrc.2022.01.097

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Preparation and characterization of 2-deacetyl-3-O-sulfo-heparosan and its antitumor effects via the fibroblast growth factor receptor pathway

Authors: Zhengqi Zha, Yaoyao Liu, Yinghua Miao, Shiying Liao, Su-Yan Wang, Huiling Tang, Hongping Yin

Journal: Int J Biol Macromol

PubMed ID: 34998873

Doi: 10.1016/j.ijbiomac.2021.12.098

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A phage parasite deploys a nicking nuclease effector to inhibit viral host replication

Authors: Kristen N LeGault, Zachary K Barth, Peter DePaola, Kimberley D Seed

Journal: Nucleic Acids Res

PubMed ID: 35066583

Doi: 10.1093/nar/gkac002

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Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model

Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto

Journal: Toxics

PubMed ID: 35051082

Doi: 10.3390/toxics10010040

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Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model

Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto

Journal: Toxics

PubMed ID: 35051082

Doi: 10.3390/toxics10010040

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The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione

Authors: Mana Murae, Yoshimi Shimizu, Yuichiro Yamamoto, Asuka Kobayashi, Masumi Houri, Tetsuya Inoue, Takuya Irie, Ryutaro Gemba, Yosuke Kondo, Yoshio Nakano, Satoru Miyazaki, Daisuke Yamada, Akiyoshi Saitoh, Isao Ishii, Taishi Onodera, Yoshimasa Takahashi, Takaji Wakita, Masayoshi Fukasawa, Kohji Noguchi

Journal: Biochem Biophys Res Commun

PubMed ID: 35123263

Doi: 10.1016/j.bbrc.2022.01.106

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The function of SARS-CoV-2 spike protein is impaired by disulfide-bond disruption with mutation at cysteine-488 and by thiol-reactive N-acetyl-cysteine and glutathione

Journal: Biochem Biophys Res Commun

PubMed ID: 35123263

Doi: 10.1016/j.bbrc.2022.01.106

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lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway

Authors: Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang

Journal: Mediators Inflamm

PubMed ID: 35125964

Doi: 10.1155/2022/6979117

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Transport Turnover Rates for Human OCT2 and MATE1 Expressed in Chinese Hamster Ovary Cells

Authors: Xiaohong Zhang, Stephen H Wright

Journal: Int J Mol Sci

PubMed ID: 35163393

Doi: 10.3390/ijms23031472

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Solid-Phase Extraction Approaches for Improving Oligosaccharide and Small Peptide Identification with Liquid Chromatography-High-Resolution Mass Spectrometry: A Case Study on Proteolyzed Almond Extract

Authors: Yu-Ping Huang, Randall C Robinson, Fernanda Furlan Goncalves Dias, Juliana Maria Leite Nobrega de Moura Bell, Daniela Barile

Journal: Foods

PubMed ID: 35159490

Doi: 10.3390/foods11030340

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Heterologous immunization with BNT162b2 followed by mRNA-1273 in dialysis patients: seroconversion and presence of neutralizing antibodies

Authors: Niko Kohmer, Holger F Rabenau, Sandra Ciesek, Bernhard K Krämer, Uwe Göttmann, Christine Keller, Daniela Rose, Carsten Blume, Michael Thomas, Alexander Lammert, Anne Lammert

Journal: Nephrol Dial Transplant

PubMed ID: 35099023

Doi: 10.1093/ndt/gfac018

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SARS-CoV-2 Seroprevalence Among Whole Blood Donors During First Wave of Covid-19 Pandemic in India

Authors: Srinivasa Rao Chunchu, Ushasree Ravula, Vikram Kumar Gente, Srinivas Bacchu, S Pandu Ranga Rao, Srujaleswari Mooli

Journal: Indian J Hematol Blood Transfus

PubMed ID: 35125705

Doi: 10.1007/s12288-021-01512-y

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LbCas12a-D156R Efficiently Edits Effector Binding Elements to Generate Canker-Resistant Citrus Plants

Authors: Hongge Jia, Yuanchun Wang, Hang Su, Xiaoen Huang, Nian Wang

Journal: Cells

PubMed ID: 35159125

Doi: 10.3390/cells11030315

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Assessment on anti-SARS-CoV-2 receptor-binding domain antibodies among CoronaVac-vaccinated Indonesian adults

Authors: Juandy Jo, Astia Sanjaya, Reinhard Pinontoan, Maroloan Aruan, Rury Mega Wahyuni, Venansi Viktaria

Journal: Clin Exp Vaccine Res

PubMed ID: 35223672

Doi: 10.7774/cevr.2022.11.1.116

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Directed Evolution of Replication-Competent Double-Stranded DNA Bacteriophage toward New Host Specificity

Authors: Jing Liang, Huibin Zhang, Yee Ling Tan, Huimin Zhao, Ee Lui Ang

Journal: ACS Synth Biol

PubMed ID: 35090114

Doi: 10.1021/acssynbio.1c00319

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NanoBRET in C elegans illuminates functional receptor interactions in real time

Authors: Victoria Elisabeth Groß, Miron Mikhailowitsch Gershkovich, Torsten Schöneberg, Anette Kaiser, Simone Prömel

Journal: BMC Mol Cell Biol

PubMed ID: 35100990

Doi: 10.1186/s12860-022-00405-w

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Ethylene response factor MdERF4 and histone deacetylase MdHDA19 suppress apple fruit ripening through histone deacetylation of ripening related genes

Authors: Yanan Hu, Zhenyun Han, Ting Wang, Hua Li, Qiqi Li, Shuai Wang, Ji Tian, Yi Wang, Xinzhong Zhang, Xuefeng Xu, Zhenhai Han, Peitao Lü, Ting Wu

Journal: Plant Physiol

PubMed ID: 35088866

Doi: 10.1093/plphys/kiac016

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Speed dating for enzymes! Finding the perfect phosphopantetheinyl transferase partner for your polyketide synthase

Authors: Tobias Bruun Pedersen, Mikkel Rank Nielsen, Sebastian Birkedal Kristensen, Eva Mie Lang Spedtsberg, Trine Sørensen, Celine Petersen, Jens Muff, Teis Esben Sondergaard, Kåre Lehmann Nielsen, Reinhard Wimmer, Donald Max Gardiner, Jens Laurids Sørensen

Journal: Microb Cell Fact

PubMed ID: 35012550

Doi: 10.1186/s12934-021-01734-9

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Initiator-Directed Transcription: Fission Yeast Nmtl Initiator Directs Preinitiation Complex Formation and Transcriptional Initiation

Authors: Diego A Rojas, Fabiola Urbina, Lucía Valenzuela-Pérez, Lorenzo Leiva, Vicente J Miralles, Edio Maldonado

Journal: Genes (Basel)

PubMed ID: 35205301

Doi: 10.3390/genes13020256

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SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease

Authors: Stefania Colarusso, Federica Ferrigno, Simona Ponzi, Francesca Pavone, Immacolata Conte, Luigi Abate, Elisa Beghetto, Antonino Missineo, Jerome Amaudrut, Alberto Bresciani, Giacomo Paonessa, Licia Tomei, Christian Montalbetti, Elisabetta Bianchi, Carlo Toniatti, Jesus M Ontoria

Journal: Bioorg Med Chem

PubMed ID: 35123179

Doi: 10.1016/j.bmc.2022.116631

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Evidence for the Rapid and Divergent Evolution of Mycoplasmas: Structural and Phylogenetic Analysis of Enolases

Authors: Rong Chen, Lin Zhao, Rong Gan, Zhixin Feng, Chenxi Cui, Xing Xie, Fei Hao, Zhenzhen Zhang, Li Wang, Tingting Ran, Weiwu Wang, Shuijun Zhang, Yufeng Li, Wei Zhang, Maoda Pang, Qiyan Xiong, Guoqing Shao

Journal: Front Mol Biosci

PubMed ID: 35145997

Doi: 10.3389/fmolb.2021.811106

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The CinB Nuclease from No Is Sufficient for Induction of Cytoplasmic Incompatibility in

Authors: Guangxin Sun, Mengwen Zhang, Hongli Chen, Mark Hochstrasser

Journal: MBio

PubMed ID: 35073749

Doi: 10.1128/mbio.03177-21

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A De Novo Optimized Cell-Free System for the Expression of Soluble and Active Human Tumor Necrosis Factor-Alpha

Authors: Nawal Abd El-Baky, Esmail M El-Fakharany, Soraya A Sabry, Ehab R El-Helow, Elrashdy Mustafa Redwan, Amira Sabry

Journal: Biology (Basel)

PubMed ID: 35205024

Doi: 10.3390/biology11020157

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Orthogonal proteomics methods to unravel the HOTAIR interactome

Authors: Louis Delhaye, Edith De Bruycker, Pieter-Jan Volders, Daria Fijalkowska, Delphine De Sutter, Sven Degroeve, Lennart Martens, Pieter Mestdagh, Sven Eyckerman

Journal: Sci Rep

PubMed ID: 35087108

Doi: 10.1038/s41598-022-05405-6

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Ginger nanoparticles mediated induction of Foxa2 prevents high-fat diet-induced insulin resistance

Authors: Anil Kumar, Kumaran Sundaram, Yun Teng, Jingyao Mu, Mukesh K Sriwastva, Lifeng Zhang, Joshua L Hood, Jun Yan, Xiang Zhang, Juw Won Park, Michael L Merchant, Huang-Ge Zhang

Journal: Theranostics

PubMed ID: 35154496

Doi: 10.7150/thno.62514

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Immunogenicity of Oxford-AstraZeneca COVID-19 Vaccine in Vietnamese Health-Care Workers

Authors: Nguyen Van Vinh Chau, Lam Anh Nguyet, Nguyen Thanh Truong, Le Mau Toan, Nguyen Thanh Dung, Le Manh Hung, Mai Thanh Nhan, Dinh Nguyen Huy Man, Nghiem My Ngoc, Huynh Phuong Thao, Tran Nguyen Hoang Tu, Huynh Kim Mai, Do Thai Hung, Nguyen Thi Han Ny, Le Kim Thanh, Nguyen To Anh, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Lam Minh Yen, Marc Choisy, Tran Tan Thanh, Guy Thwaites, Le Van Tan

Journal: Am J Trop Med Hyg

PubMed ID: 34996048

Doi: 10.4269/ajtmh.21-0849

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The Predictive Efficacy of Serum Exosomal microRNA-122 and microRNA-148a for Hepatocellular Carcinoma Based on Smart Healthcare

Authors: Peng Deng, Mi Li, Yuni Wu

Journal: J Healthc Eng

PubMed ID: 35028121

Doi: 10.1155/2022/5914541

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NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway

Authors: Bo Li, Qian Xiao, Liping Shan, Yongsheng Song

Journal: Cell Cycle

PubMed ID: 34974790

Doi: 10.1080/15384101.2021.2021050

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Involvement of β-cyanoalanine synthase (β-CAS) and sulfurtransferase (ST) in cyanide (CN) assimilation in rice seedlings

Authors: Yu-Xi Feng, Cheng-Zhi Li, Yu-Juan Lin, Xiao-Zhang Yu

Journal: Chemosphere

PubMed ID: 35101430

Doi: 10.1016/j.chemosphere.2022.133789

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Alpha-Soluble NSF Attachment Protein Prevents the Cleavage of the SARS-CoV-2 Spike Protein by Functioning as an Interferon-Upregulated Furin Inhibitor

Authors: Jinliang Wang, Jie Luo, Zhiyuan Wen, Xinxin Wang, Lei Shuai, Gongxun Zhong, Chong Wang, Ziruo Sun, Weiye Chen, Jinying Ge, Renqiang Liu, Xijun Wang, Zhigao Bu

Journal: MBio

PubMed ID: 35012335

Doi: 10.1128/mbio.02443-21

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Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells

Authors: Fei Liao, Jing Zhang, Yangyang Hu, Alireza Hassani Najafabadi, James J Moon, Max S Wicha, Bashir Kaspo, Joel Whitfield, Alfred E Chang, Qiao Li

Journal: Cancer Immunol Immunother

PubMed ID: 35098344

Doi: 10.1007/s00262-021-03129-6

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Severity of adverse reactions is associated with T-cell response in mRNA-1273 vaccinated health care workers

Authors: Hanna Klingel, Maike Lauen, Alexander Krüttgen, Matthias Imöhl, Michael Kleines

Journal: Clin Exp Vaccine Res

PubMed ID: 35223673

Doi: 10.7774/cevr.2022.11.1.121

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Mesenchymal Stem Cell-Derived Exosomes Improved Cerebral Infarction via Transferring miR-23a-3p to Activate Microglia

Authors: Chenglong Dong, Maogang Chen, Binggang Cai, Cheng Zhang, Guodong Xiao, Weifeng Luo

Journal: Neuromolecular Med

PubMed ID: 35001328

Doi: 10.1007/s12017-021-08686-8

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HOTAIR Induces the Downregulation of miR-200 Family Members in Gastric Cancer Cell Lines

Authors: Fatemeh Bossaghzadeh, Mohammadreza Hajjari, Abdolkarim Sheikhi, Iman Salahshourifar, Shiva Irani

Journal: Iran Biomed J

PubMed ID: 34923813

Doi: 10.52547/ibj.26.1.77

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Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages

Authors: Fangfang Yu, Wenxia Tian, Jie Dong

Journal: Int Immunopharmacol

PubMed ID: 35045357

Doi: 10.1016/j.intimp.2021.108514

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RBP4 regulates androgen receptor expression and steroid synthesis in Sertoli cells from Bactrian camels

Authors: Qi Wang, Quanwei Zhang, Yina Li, Xingxu Zhao, Yong Zhang

Journal: Reprod Domest Anim

PubMed ID: 35014100

Doi: 10.1111/rda.14081

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UM171A-induced ROS promote antigen cross-presentation of immunogenic peptides by bone marrow-derived mesenchymal stromal cells

Authors: Natasha Salame, Jean-Pierre Bikorimana, Nehme El-Hachem, Wael Saad, Mazen Kurdi, Jing Zhao, Nicoletta Eliopoulos, Riam Shammaa, Moutih Rafei

Journal: Stem Cell Res Ther

PubMed ID: 35012668

Doi: 10.1186/s13287-021-02693-z

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Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours

Authors: Xiaoyu Yu, Ying Bai, Bing Han, Minzi Ju, Tianci Tang, Ling Shen, Mingyue Li, Li Yang, Zhao Zhang, Guoku Hu, Jie Chao, Yuan Zhang, Honghong Yao

Journal: J Extracell Vesicles

PubMed ID: 35029057

Doi: 10.1002/jev2.12185

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Cloning and Functional Characterization of a Double-Stranded RNA-Degrading Nuclease in the Tawny Crazy Ant ()

Authors: Jiaxin Lei, Yongan Tan, Fabian List, Robert Puckett, Aaron M Tarone, Edward L Vargo, Keyan Zhu-Salzman

Journal: Front Physiol

PubMed ID: 35153841

Doi: 10.3389/fphys.2022.833652

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Safety and Immunogenicity of the Third Booster Dose with Inactivated, Viral Vector, and mRNA COVID-19 Vaccines in Fully Immunized Healthy Adults with Inactivated Vaccine

Authors: Sitthichai Kanokudom, Suvichada Assawakosri, Nungruthai Suntronwong, Chompoonut Auphimai, Pornjarim Nilyanimit, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Ritthideach Yorsaeng, Donchida Srimuan, Thaksaporn Thatsanatorn, Sirapa Klinfueng, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Sittisak Honsawek, Yong Poovorawan

Journal: Vaccines (Basel)

PubMed ID: 35062747

Doi: 10.3390/vaccines10010086

Functionality of a bicistronic construction containing and genes encoding β-hexosaminidase A for cell-mediated therapy of GM2 gangliosidoses

Authors: Alisa A Shaimardanova, Daria S Chulpanova, Valeriya V Solovyeva, Aleksandr M Aimaletdinov, Albert A Rizvanov

Journal: Neural Regen Res

PubMed ID: 34100447

Doi: 10.4103/1673-5374.314310

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Identification and characterization of natural PR-1 protein as major allergen from Humulus japonicus pollen

Authors: Ye Wang, Ling-Xiao Tan, Zhi-Qiang Xu, Yong-Xin Jiao, Dan-Xuan Zhu, Yong-Shi Yang, Ji-Fu Wei, Jin-Lyu Sun, Man Tian

Journal: Mol Immunol

PubMed ID: 36525884

Doi: 10.1016/j.molimm.2022.11.023

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Surveillance of emerging infectious diseases for biosecurity

Authors: Rongzhang Hao, Yuqi Liu, Wanzhu Shen, Rongtao Zhao, Bo Jiang, Hongbin Song, Muyang Yan, Hui Ma

Journal: Sci China Life Sci

PubMed ID: 35287183

Doi: 10.1007/s11427-021-2071-x

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In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins

Authors: Jérôme Montnach, Laila Ananda Blömer, Ludivine Lopez, Luiza Filipis, Hervé Meudal, Aude Lafoux, Sébastien Nicolas, Duong Chu, Cécile Caumes, Rémy Béroud, Chris Jopling, Frank Bosmans, Corinne Huchet, Céline Landon, Marco Canepari, Michel De Waard

Journal: Nat Commun

PubMed ID: 35058427

Doi: 10.1038/s41467-022-27974-w

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Predictive Factors for Neutralizing Antibody Levels Nine Months after Full Vaccination with BNT162b2: Results of a Machine Learning Analysis

Authors: Dimitris Papadopoulos, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Zoi Evangelakou, Panagiotis Malandrakis, Maria S Manola, Despoina D Gianniou, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos, Vangelis Karalis, Evangelos Terpos

Journal: Biomedicines

PubMed ID: 35203412

Doi: 10.3390/biomedicines10020204

A biomimetic enzyme-linked immunosorbent assay (BELISA) for the analysis of gonadorelin by using molecularly imprinted polymer-coated microplates

Authors: Francesca Torrini, Laura Caponi, Andrea Bertolini, Pasquale Palladino, Francesca Cipolli, Alessandro Saba, Aldo Paolicchi, Simona Scarano, Maria Minunni

Journal: Anal Bioanal Chem

PubMed ID: 35028691

Doi: 10.1007/s00216-021-03867-7

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Reconstitution of purified membrane protein dimers in lipid nanodiscs with defined stoichiometry and orientation using a split GFP tether

Authors: Elise S Bruguera, Jacob P Mahoney, William I Weis

Journal: J Biol Chem

PubMed ID: 35074428

Doi: 10.1016/j.jbc.2022.101628

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Recombinant Pap31 for the Diagnosis of Canine and Human Bartonelloses

Authors: Pradeep Neupane, Ricardo G Maggi, Manoj Basnet, Erin Lashnits, Gerard P Andrews, Edward B Breitschwerdt

Journal: Pathogens

PubMed ID: 35215127

Doi: 10.3390/pathogens11020182

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Structure of the human ATM kinase and mechanism of Nbs1 binding

Authors: Christopher Warren, Nikola P Pavletich

Journal: Elife

PubMed ID: 35076389

Doi: 10.7554/eLife.74218

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Two phylogenetically unrelated peptide-receptor modules jointly regulate lateral root initiation via a partially shared signaling pathway in Arabidopsis thaliana

Authors: Joris Jourquin, Ana Ibis Fernandez, Boris Parizot, Ke Xu, Wim Grunewald, Akihito Mamiya, Hidehiro Fukaki, Tom Beeckman

Journal: New Phytol

PubMed ID: 34913488

Doi: 10.1111/nph.17919

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Transcriptome analysis of Leucojum aestivum and identification of genes involved in norbelladine biosynthesis

Authors: Laurence Tousignant, Aracely Maribel Diaz-Garza, Bharat Bhusan Majhi, Sarah-Eve Gélinas, Aparna Singh, Isabel Desgagne-Penix

Journal: Planta

PubMed ID: 34981205

Doi: 10.1007/s00425-021-03741-x

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Plant-Based Vaccines in Combat against Coronavirus Diseases

Authors: Benita Ortega-Berlanga, Tomasz Pniewski

Journal: Vaccines (Basel)

PubMed ID: 35214597

Doi: 10.3390/vaccines10020138

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NMR Detection and Structural Modeling of the Ethylene Receptor LeETR2 from Tomato

Authors: Shukun Wei, Yaqing Yang, Yuan Yuan, Lingyu Du, Hongjuan Xue, Bo OuYang

Journal: Membranes (Basel)

PubMed ID: 35207029

Doi: 10.3390/membranes12020107

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Genome-Wide Identification and Expression Profiles of Genes in L

Authors: Meng Lu, Xiang-Xiao Meng, Yi-Ming Zhang, Xue-Wen Zhu, Jun Li, Wei-Qiang Chen, Hui-Hua Wan, Si-Fan Wang, Xue Cao, Wei Sun, Yao-Lei Mi, Jun-Wen Zhai

Journal: Cannabis Cannabinoid Res

PubMed ID: 35020417

Doi: 10.1089/can.2021.0153

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Hemagglutinin-based DNA vaccines containing trimeric self-assembling nanoparticles confer protection against influenza

Authors: Yongbo Qiao, Shenghui Jin, Jiaojiao Nie, Yaotian Chang, Bo Wang, Shanshan Guan, Qinghan Li, Yuhua Shi, Wei Kong, Yaming Shan

Journal: J Leukoc Biol

PubMed ID: 35040188

Doi: 10.1002/JLB.6A1021-535R

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Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase

Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek

Journal: Cells

PubMed ID: 35011726

Doi: 10.3390/cells11010165

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Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase

Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek

Journal: Cells

PubMed ID: 35011726

Doi: 10.3390/cells11010165

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Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants

Authors: Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran

Journal: Viruses

PubMed ID: 35215823

Doi: 10.3390/v14020230

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Development of a Salmonella-based oral vaccine to control intestinal colonization of Shiga-toxin-producing Escherichia coli (STEC) in animals

Authors: Florencia Iannino, Paula J Uriza, Cecilia M Duarte, María V Pepe, Mara S Roset, Gabriel Briones

Journal: Vaccine

PubMed ID: 35086742

Doi: 10.1016/j.vaccine.2022.01.032

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theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions

Authors: Teresa Lopes Gomes, Virgínia de Oliveira-Marques, Richard John Hampson, António Jacinto, Luciana Vieira de Moraes, Rui Gonçalo Martinho

Journal: Front Pharmacol

PubMed ID: 35069190

Doi: 10.3389/fphar.2021.752787

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Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR

Authors: Zhenyu Wang, Jing Chen, Qiong-Ge Zhang, Kai Huang, Dan Ma, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 35085949

Doi: 10.1016/j.vetmic.2022.109354

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Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome

Authors: Juan Manuel Orozco Rodriguez, Ewa Krupinska, Hanna Wacklin-Knecht, Wolfgang Knecht

Journal: Nucleosides Nucleotides Nucleic Acids

PubMed ID: 35094635

Doi: 10.1080/15257770.2021.2023749

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Penetration of the SARS-CoV-2 Spike Protein across the Blood-Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing

Authors: Dániel Petrovszki, Fruzsina R Walter, Judit P Vigh, Anna Kocsis, Sándor Valkai, Mária A Deli, András Dér

Journal: Biomedicines

PubMed ID: 35052867

Doi: 10.3390/biomedicines10010188

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