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CryoEM analysis of small plant biocatalysts at sub-2 Å resolution
Authors: Nicole Dimos, Carl P O Helmer, Andrea M Chánique, Markus C Wahl, Robert Kourist, Tarek Hilal, Bernhard Loll
Journal: Acta Crystallogr D Struct Biol
PubMed ID: 34981767
Doi: 10.1107/S205979832101216X
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Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin
Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng
Journal: Pharmaceutics
PubMed ID: 35057038
Doi: 10.3390/pharmaceutics14010144
Products & Services: Plasmid DNA Preparation   
Eradication of Myrosinase-Tethered Cancer Cells by Allyl Isothiocyanate Derived from Enzymatic Hydrolysis of Sinigrin
Authors: Ammar Tarar, Esmael M Alyami, Ching-An Peng
Journal: Pharmaceutics
PubMed ID: 35057038
Doi: 10.3390/pharmaceutics14010144
Products & Services: Plasmid DNA Preparation   
Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection
Authors: Xiaoting Jin, Jingxu Zhang, Yanting Li, Ze Zhang, Tenglong Cui, Yuanyuan Wang, Linlin Yao, Xiaoxi Yang, Guangbo Qu, Yuxin Zheng, Guibin Jiang
Journal: Environ Sci Technol
PubMed ID: 35049283
Doi: 10.1021/acs.est.1c07172
Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain
Authors: Nathaniel L Miller, Thomas Clark, Rahul Raman, Ram Sasisekharan
Journal: Cell Rep Med
PubMed ID: 35233548
Doi: 10.1016/j.xcrm.2022.100527
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Conditional Alternative Protein Splicing Promoted by Inteins from
Authors: Vaishnavi R Yalala, Abigeal K Lynch, Kenneth V Mills
Journal: Biochemistry
PubMed ID: 35073064
Doi: 10.1021/acs.biochem.1c00788
Products & Services: Plasmid DNA Preparation   
Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain
Authors: Nathaniel L Miller, Thomas Clark, Rahul Raman, Ram Sasisekharan
Journal: Cell Rep Med
PubMed ID: 35233548
Doi: 10.1016/j.xcrm.2022.100527
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Genome-wide identification and expression profile of YABBY genes in
Authors: Chengru Li, Na Dong, Liming Shen, Meng Lu, Junwen Zhai, Yamei Zhao, Lei Chen, Zhiting Wan, Zhongjian Liu, Hui Ren, Shasha Wu
Journal: PeerJ
PubMed ID: 35036123
Doi: 10.7717/peerj.12558
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Production and application of mouse monoclonal antibodies targeting linear epitopes in pB602L of African swine fever virus
Authors: Pengfei Wang, Chunguo Liu, Shida Wang, Lili Wen, Zhibin Shi, Yue Chi, Ming Wang, Zaisi Liu, Zhenzhao Sun, Lili Wei, Decheng Yang, Xijun He, Jingfei Wang
Journal: Arch Virol
PubMed ID: 34984562
Doi: 10.1007/s00705-021-05335-0
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Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia
Authors: Fangyi Yao, Cui Zhao, Fangmin Zhong, Tingyu Qin, Shuqi Li, Jing Liu, Bo Huang, Xiaozhong Wang
Journal: PeerJ
PubMed ID: 35111390
Doi: 10.7717/peerj.12616
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Bioinformatics analysis and identification of hub genes and immune-related molecular mechanisms in chronic myeloid leukemia
Authors: Fangyi Yao, Cui Zhao, Fangmin Zhong, Tingyu Qin, Shuqi Li, Jing Liu, Bo Huang, Xiaozhong Wang
Journal: PeerJ
PubMed ID: 35111390
Doi: 10.7717/peerj.12616
Products & Services: Custom DNA/RNA Oligos   
The Novel microRNA Rno-miR-686-3p Is Associated with the Ischaemic Penumbra
Authors: Wei Wang, Jin-Pin Li, Jing-Li Liu
Journal: Eur Neurol
PubMed ID: 35100587
Doi: 10.1159/000521491
Products & Services: DNA Sequencing   
Self-Assembly of Flagellin into Immunostimulatory Ring-like Nanostructures as an Antigen Delivery System
Authors: Mélanie Côté-Cyr, Ximena Zottig, Laurie Gauthier, Denis Archambault, Steve Bourgault
Journal: ACS Biomater Sci Eng
PubMed ID: 35080372
Doi: 10.1021/acsbiomaterials.1c01332
Products & Services: Gene Synthesis   
Role of PG0192 and PG0193 in the modulation of pro-inflammatory cytokines in macrophages in response to Porphyromonas gingivalis
Authors: Hongyan Wang, Wenying Peng, Guangyu Zhang, Muzhou Jiang, Jian Zhao, Xue Zhao, Yaping Pan, Li Lin
Journal: Eur J Oral Sci
PubMed ID: 35049069
Doi: 10.1111/eos.12851
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Role of PG0192 and PG0193 in the modulation of pro-inflammatory cytokines in macrophages in response to Porphyromonas gingivalis
Authors: Hongyan Wang, Wenying Peng, Guangyu Zhang, Muzhou Jiang, Jian Zhao, Xue Zhao, Yaping Pan, Li Lin
Journal: Eur J Oral Sci
PubMed ID: 35049069
Doi: 10.1111/eos.12851
Products & Services: GenParts™ DNA Fragments   
Protocol for structure determination of SARS-CoV-2 main protease at near-physiological-temperature by serial femtosecond crystallography
Authors: Fatma Betul Ertem, Omur Guven, Cengizhan Buyukdag, Oktay Gocenler, Esra Ayan, Busra Yuksel, Mehmet Gul, Gozde Usta, Barıs Cakılkaya, J Austin Johnson, E Han Dao, Zhen Su, Frederic Poitevin, Chun Hong Yoon, Christopher Kupitz, Brandon Hayes, Mengning Liang, Mark S Hunter, Alexander Batyuk, Raymond G Sierra, Gihan Ketawala, Sabine Botha, Çağdaş Dağ, Hasan DeMirci
Journal: STAR Protoc
PubMed ID: 35194584
Doi: 10.1016/j.xpro.2022.101158
Large inter-individual variability of cellular and humoral immunological responses to mRNA-1273 (Moderna) vaccination against SARS-CoV-2 in health care workers
Authors: Alexander Krüttgen, Gerhard Haase, Helga Haefner, Matthias Imöhl, Michael Kleines
Journal: Clin Exp Vaccine Res
PubMed ID: 35223670
Doi: 10.7774/cevr.2022.11.1.96
CircCDK14 Promotes Tumor Progression and Resists Ferroptosis in Glioma by Regulating PDGFRA
Authors: Simin Chen, Zhaoyu Zhang, Baoxin Zhang, Qing Huang, Yi Liu, Yi Qiu, Xinmiao Long, Minghua Wu, Zuping Zhang
Journal: Int J Biol Sci
PubMed ID: 35002529
Doi: 10.7150/ijbs.66114
Products & Services: Plasmid DNA Preparation   
Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue
Authors: Yingzi Tan, Miao Wang, Yijun Chen
Journal: ACS Synth Biol
PubMed ID: 35006674
Doi: 10.1021/acssynbio.1c00578
Products & Services: Gene Synthesis   
The Linker Region Promotes Activity and Binding Efficiency of Modular LPMO towards Polymeric Substrate
Authors: Aishwarya Srivastava, Pragya Nagar, Sumit Rathore, Nidhi Adlakha
Journal: Microbiol Spectr
PubMed ID: 35080440
Doi: 10.1128/spectrum.02697-21
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Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites
Authors: Bruna Felício Milazzotto Maldonado Porchia, Luana Raposo de Melo Moraes Aps, Ana Carolina Ramos Moreno, Jamile Ramos da Silva, Mariângela de Oliveira Silva, Natiely Silva Sales, Rubens Prince Dos Santos Alves, Clarissa Ribeiro Reily Rocha, Matheus Molina Silva, Karine Bitencourt Rodrigues, Tácita Borges Barros, Roberta Liberato Pagni, Patrícia da Cruz Souza, Mariana de Oliveira Diniz, Luís Carlos de Souza Ferreira
Journal: Int J Biol Sci
PubMed ID: 34975315
Doi: 10.7150/ijbs.56644
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Modified Sawhorse Waveform for the Voltammetric Detection of Oxytocin
Authors: Favian A Liu, Negar Ardabili, Izaiah Brown, Harmain Rafi, Clarice Cook, Rodanthi Nikopoulou, Arianna Lopez, Shouzhong Zou, Matthew R Hartings, Alexander G Zestos
Journal: J Electrochem Soc
PubMed ID: 35185166
Doi: 10.1149/1945-7111/ac4aae
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An endogenous bornavirus-like nucleoprotein in miniopterid bats retains the RNA-binding properties of the original viral protein
Authors: Yahiro Mukai, Masayuki Horie, Shohei Kojima, Junna Kawasaki, Ken Maeda, Keizo Tomonaga
Journal: FEBS Lett
PubMed ID: 35043395
Doi: 10.1002/1873-3468.14290
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Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway
Authors: Veronica Mutti, Federica Bono, Zaira Tomasoni, Leonardo Bontempi, Adele Guglielmi, Silvia Bolognin, Jens C Schwamborn, Cristina Missale, Chiara Fiorentini
Journal: Mol Neurobiol
PubMed ID: 35044626
Doi: 10.1007/s12035-022-02748-z
Products & Services: Gene Synthesis   
miR-541-3p Promoted Porcine Reproductive and Respiratory Syndrome Virus 2 (PRRSV-2) Replication by Targeting Interferon Regulatory Factor 7
Authors: Xibao Shi, Yuanhao Yang, Xiaozhuan Zhang, Xiaobo Chang, Jing Chen, Chao Wang, Aiping Wang, Jianhua Wang, Jianru Qin, Xianlong Ye, Wei Jin, Gaiping Zhang
Journal: Viruses
PubMed ID: 35062330
Doi: 10.3390/v14010126
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Expression of phenylalanine ammonia lyases in Synechocystis sp PCC 6803 and subsequent improvements of sustainable production of phenylpropanoids
Authors: Kateryna Kukil, Pia Lindberg
Journal: Microb Cell Fact
PubMed ID: 35012528
Doi: 10.1186/s12934-021-01735-8
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Targeted deletion of liver-expressed Choriogenin L results in the production of soft eggs and infertility in medaka, Oryzias latipes
Authors: Kenji Murata, Masato Kinoshita
Journal: Zoological Lett
PubMed ID: 34983666
Doi: 10.1186/s40851-021-00185-9
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Anion binding to a cationic europium(III) probe enables the first real-time assay of heparan sulfotransferase activity
Authors: Simon Wheeler, Colum Breen, Yong Li, Sarah H Hewitt, Erin Robertson, Edwin A Yates, Igor L Barsukov, David G Fernig, Stephen J Butler
Journal: Org Biomol Chem
PubMed ID: 34951618
Doi: 10.1039/d1ob02071d
Multiplex genome editing of mammalian cells for producing recombinant heparin
Authors: Bryan E Thacker, Kristen J Thorne, Colin Cartwright, Jeeyoung Park, Kimberly Glass, Annie Chea, Benjamin P Kellman, Nathan E Lewis, Zhenping Wang, Anna Di Nardo, Susan T Sharfstein, Walter Jeske, Jeanine Walenga, John Hogwood, Elaine Gray, Barbara Mulloy, Jeffrey D Esko, Charles A Glass
Journal: Metab Eng
PubMed ID: 35038554
Doi: 10.1016/j.ymben.2022.01.002
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Multiplex genome editing of mammalian cells for producing recombinant heparin
Authors: Bryan E Thacker, Kristen J Thorne, Colin Cartwright, Jeeyoung Park, Kimberly Glass, Annie Chea, Benjamin P Kellman, Nathan E Lewis, Zhenping Wang, Anna Di Nardo, Susan T Sharfstein, Walter Jeske, Jeanine Walenga, John Hogwood, Elaine Gray, Barbara Mulloy, Jeffrey D Esko, Charles A Glass
Journal: Metab Eng
PubMed ID: 35038554
Doi: 10.1016/j.ymben.2022.01.002
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Genome-wide analysis and transcriptional reprogrammings of MYB superfamily revealed positive insights into abiotic stress responses and anthocyanin accumulation in Carthamus tinctorius L
Authors: Yingqi Hong, Naveed Ahmad, Jianyi Zhang, Yanxi Lv, Xinyue Zhang, Xintong Ma, Liu Xiuming, Yao Na
Journal: Mol Genet Genomics
PubMed ID: 34978004
Doi: 10.1007/s00438-021-01839-1
Products & Services: Protein Tools   
Knockdown of DPP4 promotes the proliferation and the activation of the CREB/aromatase pathway in ovarian granulosa cells
Authors: Lina Lin, Liman Wang
Journal: Mol Med Rep
PubMed ID: 35014677
Doi: 10.3892/mmr.2022.12589
Products & Services: Gene Synthesis   
Highly efficient A-to-G base editing by ABE8.17 in rabbits
Authors: Ding Zhao , Yuqiang Qian , Jinze Li , Zhanjun Li , Liangxue Lai
Journal: Mol Ther Nucleic Acids .
PubMed ID: 35282412
Doi: 10.1016/j.omtn.2022.01.019
Products & Services: Gene Synthesis   
Optimization of Protoplast Isolation and Transformation for a Pilot Study of Genome Editing in Peanut by Targeting the Allergen Gene
Authors: Sudip Biswas, Nancy J Wahl, Michael J Thomson, John M Cason, Bill F McCutchen, Endang M Septiningsih
Journal: Int J Mol Sci
PubMed ID: 35055026
Doi: 10.3390/ijms23020837
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Performance of the cobas® HBV RNA automated investigational assay for the detection and quantification of circulating HBV RNA in chronic HBV patients
Authors: Caroline Scholtès, Aaron T Hamilton, Marie-Laure Plissonnier, Caroline Charre, Beth Scott, Ling Wang, Françoise Berby, Janine French, Barbara Testoni, Alan Blair, Miroslava Subic, Matthias Hoppler, Andreas Lankenau, Andreas Grubenmann, Massimo Levrero, Marintha L Heil, Fabien Zoulim
Journal: J Clin Virol
PubMed ID: 35427860
Doi: 10.1016/j.jcv.2022.105150
Products & Services: Molecular Biology Reagents   
Reactivity of DENV-positive sera against recombinant envelope proteins produced in bacteria and eukaryotic cells
Authors: Higo Fernando Santos Souza, Arthur Baruel Zaneti, Bianca da Silva Almeida, Jéssica Amaral Martinho, Márcio Massao Yamamoto, Daniela Santoro Rosa, Renata Denzegrini Slhessarenko, Silvia Beatriz Boscardin
Journal: Immunol Res
PubMed ID: 36192522
Doi: 10.1007/s12026-022-09326-4
Engineered bacterial host for genetic encoding of physiologically stable protein nitration
Authors: Nikolaj G Koch, Tobias Baumann, Jessica H Nickling, Anna Dziegielewski, Nediljko Budisa
Journal: Front Mol Biosci
PubMed ID: 36353730
Doi: 10.3389/fmolb.2022.992748
Products & Services: Gene Synthesis   
Intra-amniotic mesenchymal stem cell therapy improves the amniotic fluid microenvironment in rat spina bifida aperta fetuses
Authors: Xiaowei Wei, Wei Ma, Hui Gu, Dan Liu, Wenting Luo, Songying Cao, Shanshan Jia, Tianchu Huang, Yiwen He, Yuzuo Bai, Weilin Wang, Zhengwei Yuan
Journal: Cell Prolif
PubMed ID: 36266504
Doi: 10.1111/cpr.13354
Products & Services: Gene Synthesis   
Tongxinluo prevents chronic obstructive pulmonary disease complicated with atherosclerosis by inhibiting ferroptosis and protecting against pulmonary microvascular barrier dysfunction
Authors: Yafen Wang, Xiangnan Kuang, Yujie Yin , Ningxin Han, Liping Chang, Hongtao Wang, Yunlong Hou, Huixin Li, Zhen Li , Yi Liu, Yuanjie Hao , Yaru Wei, Xiaoqi Wang, Zhenhua Jia
Journal: Biomed Pharmacother
PubMed ID: 34740097
Doi: 10.1016/j.biopha.2021.112367
CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy
Authors: Dan Wang, Ling Chen, Chengbi Li, Quanxin Long, Qing Yang, Ailong Huang, Hua Tang
Journal: J Nanobiotechnology
PubMed ID: 34991617
Doi: 10.1186/s12951-021-01233-4
Products & Services: GenCrispr Cas9 Genome Editing   
Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase
Authors: Chia Wei Hsu, Mark L Sowers, Tuvshintugs Baljinnyam, Jason L Herring, Linda C Hackfeld, Hui Tang, Kangling Zhang, Lawrence C Sowers
Journal: J Biol Chem
PubMed ID: 35085553
Doi: 10.1016/j.jbc.2022.101638
Products & Services: Gene Synthesis   
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection
Authors: Bojie Xu , Ruicheng Yang , Bo Yang , Liang Li , Jiaqi Chen , Jiyang Fu , Xinyi Qu , Dong Huo , Chen Tan , Huanchun Chen , Zhong Peng , Xiangru Wang
Journal: Mol Brain
PubMed ID: 34980188
Doi: 10.1186/s13041-021-00890-8
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SARS-CoV-2 S Protein Subunit 1 Elicits Ca2+ Influx – Dependent Ca2+ Signals in Pancreatic Stellate Cells and Macrophages In Situ
Authors: Julia V Gerasimenko , Ole H Petersen , Oleg V Gerasimenko
Journal: Function (Oxf)
Doi: 10.1093/function/zqac002
Products & Services: Recombinant Proteins   
Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus
Authors: Bryce P Johnson , Vikas Kumar , Erin M Scull , Leonard M Thomas , Christina R Bourne , Shanteri Singh
Journal: ACS Chem Biol
PubMed ID: 34905349
Doi: 10.1021/acschembio.1c00655
Products & Services: Gene Synthesis   
Efficient Amber Suppression Ribosomal Skipping for Synthesis of Photoconditional Nanobodies
Authors: Eike F Joest, Christian Winter, Joshua S Wesalo, Alexander Deiters, Robert Tampé
Journal: ACS Synth Biol
PubMed ID: 35060375
Doi: 10.1021/acssynbio.1c00471
Products & Services: Plasmid DNA Preparation   
Protein Phosphatase 2A Deficiency in Macrophages Increases Foam Cell Formation and Accelerates Atherosclerotic Lesion Development
Authors: Rui Li, Chao Zhang, Fei Xie, Xianming Zhou, Xingjian Hu, Jiawei Shi, Xinling Du, Zhiyong Lin, Nianguo Dong
Journal: Front Cardiovasc Med
PubMed ID: 35118139
Doi: 10.3389/fcvm.2021.745009
Synthesis of broad-specificity activity-based probes for -β-mannosidases
Authors: Nicholas G S McGregor, Chi-Lin Kuo, Thomas J M Beenakker, Chun-Sing Wong, Wendy A Offen, Zachary Armstrong, Bogdan I Florea, Jeroen D C Codée, Herman S Overkleeft, Johannes M F G Aerts, Gideon J Davies
Journal: Org Biomol Chem
PubMed ID: 35015006
Doi: 10.1039/d1ob02287c
Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system
Authors: Yue Wu, Zhenling Cui, Yen-Hua Huang, Simon J de Veer, Andrey V Aralov, Zhong Guo, Shayli V Moradi, Alexandra O Hinton, Jennifer R Deuis, Shaodong Guo, Kai-En Chen, Brett M Collins, Irina Vetter, Volker Herzig, Alun Jones, Matthew A Cooper, Glenn F King, David J Craik, Kirill Alexandrov, Sergey Mureev
Journal: Nat Commun
PubMed ID: 35017494
Doi: 10.1038/s41467-021-27854-9
Products & Services: DNA Sequencing   
Dietary Isoflavones Alter Gut Microbiota and Lipopolysaccharide Biosynthesis to Reduce Inflammation
Authors: Sudeep Ghimire, Nicole M Cady, Peter Lehman, Stephanie R Peterson, Shailesh K Shahi, Faraz Rashid, Shailendra Giri, Ashutosh K Mangalam
Journal: Gut Microbes
PubMed ID: 36179318
Doi: 10.1080/19490976.2022.2127446
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Identification of sequence-specific promoters driving polycistronic transcription initiation by RNA polymerase II in trypanosomes
Authors: Carlos Cordon-Obras, Claudia Gomez-Liñan, Sara Torres-Rusillo, Isabel Vidal-Cobo, Diana Lopez-Farfan, Alicia Barroso-Del Jesus, Domingo Rojas-Barros, Mark Carrington, Miguel Navarro
Journal: Cell Rep
PubMed ID: 35021094
Doi: 10.1016/j.celrep.2021.110221
Products & Services: GenParts™ DNA Fragments   
FACI Is a Novel CREB-H-Induced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity
Authors: Yun Cheng, Xiao-Zhuo Kang, Tao Cheng, Zi-Wei Ye, George L Tipoe, Cheng-Han Yu, Chi-Ming Wong, Baohua Liu, Chi-Ping Chan, Dong-Yan Jin
Journal: Cell Mol Gastroenterol Hepatol
PubMed ID: 35093589
Doi: 10.1016/j.jcmgh.2022.01.017
Products & Services: Stable Cell Lines   
The Impact of Tyrosine Iodination on the Aggregation and Cleavage Kinetics of MMP-9-Responsive Peptide Sequences
Authors: Douglas S MacPherson, Scott A McPhee, Brian M Zeglis, Rein V Ulijn
Journal: ACS Biomater Sci Eng
PubMed ID: 35050574
Doi: 10.1021/acsbiomaterials.1c01488
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Novel Neutralizing Epitope of PEDV S1 Protein Identified by IgM Monoclonal Antibody
Authors: Techit Thavorasak, Monrat Chulanetra, Kittirat Glab-Ampai, Karsidete Teeranitayatarn, Thaweesak Songserm, Rungrueang Yodsheewan, Nawannaporn Sae-Lim, Porntippa Lekcharoensuk, Nitat Sookrung, Wanpen Chaicumpa
Journal: Viruses
PubMed ID: 35062329
Doi: 10.3390/v14010125
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Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies
Authors: Changyoun Kim, Armine Hovakimyan, Karen Zagorski, Tatevik Antonyan, Irina Petrushina, Hayk Davtyan, Gor Chailyan, Jonathan Hasselmann, Michiyo Iba, Anthony Adame, Edward Rockenstein, Marcell Szabo, Mathew Blurton-Jones, David H Cribbs, Anahit Ghochikyan, Eliezer Masliah, Michael G Agadjanyan
Journal: npj Vaccines
PubMed ID: 35013319
Doi: 10.1038/s41541-021-00424-2
Products & Services: Gene Synthesis   
Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation
Authors: Florian J Raabe, Marius Stephan, Jan Benedikt Waldeck, Verena Huber, Damianos Demetriou, Nirmal Kannaiyan, Sabrina Galinski, Laura V Glaser, Michael C Wehr, Michael J Ziller, Andrea Schmitt, Peter Falkai, Moritz J Rossner
Journal: Cells
PubMed ID: 35053357
Doi: 10.3390/cells11020241
Products & Services: Plasmid DNA Preparation   
Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease
Authors: Yun Yang, Victor Tapias, Diana Acosta, Hui Xu, Huanlian Chen, Ruchika Bhawal, Elizabeth T Anderson, Elena Ivanova, Hening Lin, Botir T Sagdullaev, Jianer Chen, William L Klein, Kirsten L Viola, Sam Gandy, Vahram Haroutunian, M Flint Beal, David Eliezer, Sheng Zhang, Gary E Gibson
Journal: Nat Commun
PubMed ID: 35013160
Doi: 10.1038/s41467-021-27572-2
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Shoc2 recognizes bacterial flagellin and mediates antibacterial Erk/Stat signaling in an invertebrate
Authors: Bao-Rui Zhao, Xin-Xin Wang, Xian-Wei Wang
Journal: PLoS Pathog
PubMed ID: 35073369
Doi: 10.1371/journal.ppat.1010253
The temporal gene expression profiles of calcium and phosphorus transporters in Hy-Line Brown layers
Authors: Xiaojuan Wang, Peng Li, Jingpeng Zhao, Hongchao Jiao, Hai Lin
Journal: Poult Sci
PubMed ID: 35202896
Doi: 10.1016/j.psj.2022.101736
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SARS-CoV-2 NSP13 Inhibits Type I IFN Production by Degradation of TBK1 via p62-Dependent Selective Autophagy
Authors: Chao Sui, Tongyang Xiao, Shengyuan Zhang, Hongxiang Zeng, Yi Zheng, Bingyu Liu, Gang Xu, Chengjiang Gao, Zheng Zhang
Journal: J Immunol
PubMed ID: 34996837
Doi: 10.4049/jimmunol.2100684
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Silencing of circCDC14A prevents cerebral ischemia-reperfusion injury via miR-23a-3p/CXCL12 axis
Authors: Huiyi Huo, Chao Hu, Yongxue Lu, Jinyu Zhou, Zhiguang Mai
Journal: J Biochem Mol Toxicol
PubMed ID: 34978116
Doi: 10.1002/jbt.22982
Products & Services: Gene Synthesis   
Plant-Based Vaccines in Combat against Coronavirus Diseases
Authors: Benita Ortega-Berlanga, Tomasz Pniewski
Journal: Vaccines (Basel)
PubMed ID: 35214597
Doi: 10.3390/vaccines10020138
NMR Detection and Structural Modeling of the Ethylene Receptor LeETR2 from Tomato
Authors: Shukun Wei, Yaqing Yang, Yuan Yuan, Lingyu Du, Hongjuan Xue, Bo OuYang
Journal: Membranes (Basel)
PubMed ID: 35207029
Doi: 10.3390/membranes12020107
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Genome-Wide Identification and Expression Profiles of Genes in L
Authors: Meng Lu, Xiang-Xiao Meng, Yi-Ming Zhang, Xue-Wen Zhu, Jun Li, Wei-Qiang Chen, Hui-Hua Wan, Si-Fan Wang, Xue Cao, Wei Sun, Yao-Lei Mi, Jun-Wen Zhai
Journal: Cannabis Cannabinoid Res
PubMed ID: 35020417
Doi: 10.1089/can.2021.0153
Products & Services: Protein Tools   
Hemagglutinin-based DNA vaccines containing trimeric self-assembling nanoparticles confer protection against influenza
Authors: Yongbo Qiao, Shenghui Jin, Jiaojiao Nie, Yaotian Chang, Bo Wang, Shanshan Guan, Qinghan Li, Yuhua Shi, Wei Kong, Yaming Shan
Journal: J Leukoc Biol
PubMed ID: 35040188
Doi: 10.1002/JLB.6A1021-535R
Products & Services: Mammalian Expression   
Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase
Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek
Journal: Cells
PubMed ID: 35011726
Doi: 10.3390/cells11010165
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Role of Nse1 Subunit of SMC5/6 Complex as a Ubiquitin Ligase
Authors: Peter Kolesar, Karel Stejskal, David Potesil, Johanne M Murray, Jan J Palecek
Journal: Cells
PubMed ID: 35011726
Doi: 10.3390/cells11010165
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Characterization of a Broadly Neutralizing Monoclonal Antibody against SARS-CoV-2 Variants
Authors: Tasnim Saifudin Zakir, Tao Meng, Lee Ching Pei Carmen, Justin Jang Hann Chu, Raymond Tzer Pin Lin, Mookkan Prabakaran
Journal: Viruses
PubMed ID: 35215823
Doi: 10.3390/v14020230
Products & Services: Recombinant Proteins   
theLiTE™: A Screening Platform to Identify Compounds that Reinforce Tight Junctions
Authors: Teresa Lopes Gomes, Virgínia de Oliveira-Marques, Richard John Hampson, António Jacinto, Luciana Vieira de Moraes, Rui Gonçalo Martinho
Journal: Front Pharmacol
PubMed ID: 35069190
Doi: 10.3389/fphar.2021.752787
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Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model
Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto
Journal: Toxics
PubMed ID: 35051082
Doi: 10.3390/toxics10010040
Products & Services: Endotoxin Detection & Removal System   
Suppression of Airway Allergic Reactions by a Photocatalytic Filter Using Mouse Model
Authors: Taisuke Tomonaga, Hiroto Izumi, Chinatsu Nishida, Kaori Kato, Kazuhiro Yatera, Etsushi Kuroda, Yasuo Morimoto
Journal: Toxics
PubMed ID: 35051082
Doi: 10.3390/toxics10010040
Products & Services: Endotoxin Detection & Removal System   
Porcine circovirus type 2 infection inhibits the activation of type I interferon signaling via capsid protein and host gC1qR
Authors: Zhenyu Wang, Jing Chen, Qiong-Ge Zhang, Kai Huang, Dan Ma, Qian Du, Dewen Tong, Yong Huang
Journal: Vet Microbiol
PubMed ID: 35085949
Doi: 10.1016/j.vetmic.2022.109354
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lnc-MRGPRF-6:1 Promotes M1 Polarization of Macrophage and Inflammatory Response through the TLR4-MyD88-MAPK Pathway
Authors: Dan Hu, Yuzhong Wang, Zhihuan You, Yingfei Lu, Caihong Liang
Journal: Mediators Inflamm
PubMed ID: 35125964
Doi: 10.1155/2022/6979117
Products & Services: Custom DNA/RNA Oligos   
Targeted deletion of liver-expressed Choriogenin L results in the production of soft eggs and infertility in medaka, Oryzias latipes
Authors: Kenji Murata, Masato Kinoshita
Journal: Zoological Lett
PubMed ID: 34983666
Doi: 10.1186/s40851-021-00185-9
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Active immunization combined with cisplatin confers enhanced therapeutic protection and prevents relapses of HPV-induced tumors at different anatomical sites
Authors: Bruna Felício Milazzotto Maldonado Porchia, Luana Raposo de Melo Moraes Aps, Ana Carolina Ramos Moreno, Jamile Ramos da Silva, Mariângela de Oliveira Silva, Natiely Silva Sales, Rubens Prince Dos Santos Alves, Clarissa Ribeiro Reily Rocha, Matheus Molina Silva, Karine Bitencourt Rodrigues, Tácita Borges Barros, Roberta Liberato Pagni, Patrícia da Cruz Souza, Mariana de Oliveira Diniz, Luís Carlos de Souza Ferreira
Journal: Int J Biol Sci
PubMed ID: 34975315
Doi: 10.7150/ijbs.56644
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Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice
Authors: Yi Zhang, Mufan Ji, Zhenyang Gu, Wenlong Pei, Jun Zhu, Qian Wu, Lei Li, Zhan Zhang
Journal: Toxicology
PubMed ID: 34979169
Doi: 10.1016/j.tox.2021.153088
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Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations
Authors: Anju Jaiswal, D Dash, Rashmi Singh
Journal: Toxicol Appl Pharmacol
PubMed ID: 34998855
Doi: 10.1016/j.taap.2021.115861
Products & Services: Endotoxin Detection & Removal System   
Directed Evolution of Replication-Competent Double-Stranded DNA Bacteriophage toward New Host Specificity
Authors: Jing Liang, Huibin Zhang, Yee Ling Tan, Huimin Zhao, Ee Lui Ang
Journal: ACS Synth Biol
PubMed ID: 35090114
Doi: 10.1021/acssynbio.1c00319
Products & Services: GenParts™ DNA Fragments   
Ethylene response factor MdERF4 and histone deacetylase MdHDA19 suppress apple fruit ripening through histone deacetylation of ripening related genes
Authors: Yanan Hu, Zhenyun Han, Ting Wang, Hua Li, Qiqi Li, Shuai Wang, Ji Tian, Yi Wang, Xinzhong Zhang, Xuefeng Xu, Zhenhai Han, Peitao Lü, Ting Wu
Journal: Plant Physiol
PubMed ID: 35088866
Doi: 10.1093/plphys/kiac016
Products & Services: Catalog Antibody   
Speed dating for enzymes! Finding the perfect phosphopantetheinyl transferase partner for your polyketide synthase
Authors: Tobias Bruun Pedersen, Mikkel Rank Nielsen, Sebastian Birkedal Kristensen, Eva Mie Lang Spedtsberg, Trine Sørensen, Celine Petersen, Jens Muff, Teis Esben Sondergaard, Kåre Lehmann Nielsen, Reinhard Wimmer, Donald Max Gardiner, Jens Laurids Sørensen
Journal: Microb Cell Fact
PubMed ID: 35012550
Doi: 10.1186/s12934-021-01734-9
Products & Services: Codon Optimization   
A biomimetic enzyme-linked immunosorbent assay (BELISA) for the analysis of gonadorelin by using molecularly imprinted polymer-coated microplates
Authors: Francesca Torrini, Laura Caponi, Andrea Bertolini, Pasquale Palladino, Francesca Cipolli, Alessandro Saba, Aldo Paolicchi, Simona Scarano, Maria Minunni
Journal: Anal Bioanal Chem
PubMed ID: 35028691
Doi: 10.1007/s00216-021-03867-7
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Initiator-Directed Transcription: Fission Yeast Nmtl Initiator Directs Preinitiation Complex Formation and Transcriptional Initiation
Authors: Diego A Rojas, Fabiola Urbina, Lucía Valenzuela-Pérez, Lorenzo Leiva, Vicente J Miralles, Edio Maldonado
Journal: Genes (Basel)
PubMed ID: 35205301
Doi: 10.3390/genes13020256
Products & Services: Gene Synthesis   
Closely related Salmonella Derby strains triggered distinct gut microbiota alteration
Authors: Xiaohui Yuan, Han Xue, Xiaomeng Xu, Xinan Jiao, Zhiming Pan, Yunzeng Zhang
Journal: Gut Pathog
PubMed ID: 35078518
Doi: 10.1186/s13099-022-00480-6
Products & Services: DNA Sequencing   
Inhibitory effects of specific combination of natural compounds against SARS-CoV-2 and its Alpha, Beta, Gamma, Delta, Kappa, and Mu variants
Authors: Anna Goc, Aleksandra Niedzwiecki, Vadim Ivanov, Svetlana Ivanova, Matthias Rath
Journal: Eur J Microbiol Immunol (Bp)
PubMed ID: 35060921
Doi: 10.1556/1886.2021.00022
High cell surface expression and peptide binding affinity of HLA-DQA1*05:03, a susceptible allele of neuromyelitis optica spectrum disorders (NMOSD)
Authors: Shohei Beppu, Makoto Kinoshita, Jan Wilamowski, Tadahiro Suenaga, Yoshiaki Yasumizu, Kotaro Ogawa, Teruyuki Ishikura, Satoru Tada, Toru Koda, Hisashi Murata, Naoyuki Shiraishi, Yasuko Sugiyama, Keigo Kihara, Tomoyuki Sugimoto, Hisashi Arase, Daron M Standley, Tatsusada Okuno, Hideki Mochizuki
Journal: Sci Rep
PubMed ID: 34997058
Doi: 10.1038/s41598-021-04074-1
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Porcine TRIM21 Enhances Porcine Circovirus 2 Infection and Host Immune Responses, But Inhibits Apoptosis of PCV2-Infected Cells
Authors: Lin Yang, Xiaohua Liu, Liying Zhang, Xue Li, Xinwei Zhang, Guoyu Niu, Weilong Ji, Si Chen, Hongsheng Ouyang, Linzhu Ren
Journal: Viruses
PubMed ID: 35062360
Doi: 10.3390/v14010156
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Targeted gene silencing in the nervous system with CRISPR-Cas13
Authors: Jackson E Powell, Colin K W Lim, Ramya Krishnan, Tristan X McCallister, Christian Saporito-Magriña, Maria A Zeballos, Garrett D McPheron, Thomas Gaj
Journal: Sci Adv
PubMed ID: 35044815
Doi: 10.1126/sciadv.abk2485
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Two phylogenetically unrelated peptide-receptor modules jointly regulate lateral root initiation via a partially shared signaling pathway in Arabidopsis thaliana
Authors: Joris Jourquin, Ana Ibis Fernandez, Boris Parizot, Ke Xu, Wim Grunewald, Akihito Mamiya, Hidehiro Fukaki, Tom Beeckman
Journal: New Phytol
PubMed ID: 34913488
Doi: 10.1111/nph.17919
The CinB Nuclease from No Is Sufficient for Induction of Cytoplasmic Incompatibility in
Authors: Guangxin Sun, Mengwen Zhang, Hongli Chen, Mark Hochstrasser
Journal: MBio
PubMed ID: 35073749
Doi: 10.1128/mbio.03177-21
Products & Services: Gene Synthesis   
A De Novo Optimized Cell-Free System for the Expression of Soluble and Active Human Tumor Necrosis Factor-Alpha
Authors: Nawal Abd El-Baky, Esmail M El-Fakharany, Soraya A Sabry, Ehab R El-Helow, Elrashdy Mustafa Redwan, Amira Sabry
Journal: Biology (Basel)
PubMed ID: 35205024
Doi: 10.3390/biology11020157
Products & Services: Mammalian Expression   
Orthogonal proteomics methods to unravel the HOTAIR interactome
Authors: Louis Delhaye, Edith De Bruycker, Pieter-Jan Volders, Daria Fijalkowska, Delphine De Sutter, Sven Degroeve, Lennart Martens, Pieter Mestdagh, Sven Eyckerman
Journal: Sci Rep
PubMed ID: 35087108
Doi: 10.1038/s41598-022-05405-6
Mitochondrial Dysfunction Associates With Acute T Lymphocytopenia and Impaired Functionality in COVID-19 Patients
Authors: Yufei Mo, Kelvin Kai-Wang To, Runhong Zhou, Li Liu, Tianyu Cao, Haode Huang, Zhenglong Du, Chun Yu Hubert Lim, Lok-Yan Yim, Tsz-Yat Luk, Jacky Man-Chun Chan, Thomas Shiu-Hong Chik, Daphne Pui-Ling Lau, Owen Tak-Yin Tsang, Anthony Raymond Tam, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Zhiwei Chen
Journal: Front Immunol
PubMed ID: 35095881
Doi: 10.3389/fimmu.2021.799896
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Immunogenicity of Oxford-AstraZeneca COVID-19 Vaccine in Vietnamese Health-Care Workers
Authors: Nguyen Van Vinh Chau, Lam Anh Nguyet, Nguyen Thanh Truong, Le Mau Toan, Nguyen Thanh Dung, Le Manh Hung, Mai Thanh Nhan, Dinh Nguyen Huy Man, Nghiem My Ngoc, Huynh Phuong Thao, Tran Nguyen Hoang Tu, Huynh Kim Mai, Do Thai Hung, Nguyen Thi Han Ny, Le Kim Thanh, Nguyen To Anh, Nguyen Thi Thu Hong, Le Nguyen Truc Nhu, Lam Minh Yen, Marc Choisy, Tran Tan Thanh, Guy Thwaites, Le Van Tan
Journal: Am J Trop Med Hyg
PubMed ID: 34996048
Doi: 10.4269/ajtmh.21-0849
Products & Services: SARS-CoV-2 qRT-PCR Detection Assay   
Inhibition of microRNA-448 suppresses CD4 T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus
Authors: Jing Zhang, Yun Guo, Yue Sun, Lihua Chang, Xiaofei Wang
Journal: Biochem Biophys Res Commun
PubMed ID: 35121374
Doi: 10.1016/j.bbrc.2022.01.097
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NCAPH promotes cell proliferation and inhibits cell apoptosis of bladder cancer cells through MEK/ERK signaling pathway
Authors: Bo Li, Qian Xiao, Liping Shan, Yongsheng Song
Journal: Cell Cycle
PubMed ID: 34974790
Doi: 10.1080/15384101.2021.2021050
Products & Services: Plasmid DNA Preparation   
Involvement of β-cyanoalanine synthase (β-CAS) and sulfurtransferase (ST) in cyanide (CN) assimilation in rice seedlings
Authors: Yu-Xi Feng, Cheng-Zhi Li, Yu-Juan Lin, Xiao-Zhang Yu
Journal: Chemosphere
PubMed ID: 35101430
Doi: 10.1016/j.chemosphere.2022.133789
Products & Services: Protein Tools   
Preparation and characterization of 2-deacetyl-3-O-sulfo-heparosan and its antitumor effects via the fibroblast growth factor receptor pathway
Authors: Zhengqi Zha, Yaoyao Liu, Yinghua Miao, Shiying Liao, Su-Yan Wang, Huiling Tang, Hongping Yin
Journal: Int J Biol Macromol
PubMed ID: 34998873
Doi: 10.1016/j.ijbiomac.2021.12.098
Products & Services: Plasmid DNA Preparation   
A phage parasite deploys a nicking nuclease effector to inhibit viral host replication
Authors: Kristen N LeGault, Zachary K Barth, Peter DePaola, Kimberley D Seed
Journal: Nucleic Acids Res
PubMed ID: 35066583
Doi: 10.1093/nar/gkac002
Products & Services: Gene Synthesis   
Development of a Salmonella-based oral vaccine to control intestinal colonization of Shiga-toxin-producing Escherichia coli (STEC) in animals
Authors: Florencia Iannino, Paula J Uriza, Cecilia M Duarte, María V Pepe, Mara S Roset, Gabriel Briones
Journal: Vaccine
PubMed ID: 35086742
Doi: 10.1016/j.vaccine.2022.01.032
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Mesenchymal Stem Cell-Derived Exosomes Improved Cerebral Infarction via Transferring miR-23a-3p to Activate Microglia
Authors: Chenglong Dong, Maogang Chen, Binggang Cai, Cheng Zhang, Guodong Xiao, Weifeng Luo
Journal: Neuromolecular Med
PubMed ID: 35001328
Doi: 10.1007/s12017-021-08686-8
Products & Services: ORF cDNA Clones/MolecularCloud   
Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome
Authors: Juan Manuel Orozco Rodriguez, Ewa Krupinska, Hanna Wacklin-Knecht, Wolfgang Knecht
Journal: Nucleosides Nucleotides Nucleic Acids
PubMed ID: 35094635
Doi: 10.1080/15257770.2021.2023749
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