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A Plasmodium apicoplast-targeted unique exonuclease/FEN exhibits interspecies functional differences attributable to an insertion that alters DNA-binding
Authors: Tribeni Chatterjee, Anupama Tiwari, Ritika Gupta, Himadri Shukla, Aastha Varshney, Satish Mishra, Saman Habib
Journal: Nucleic Acids Res
PubMed ID: 38888125
Doi: 10.1093/nar/gkae512
Products & Services: Gene Synthesis   
CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels
Authors: Yin Liu, Xinyi Liu, Dongyi Wei, Lu Dang, Xiaoran Xu, Shisheng Huang, Liwen Li, Sanyun Wu, Jinxian Wu, Xiaoyan Liu, Wenjun Sun, Wanyu Tao, Yongchang Wei, Xingxu Huang, Kui Li, Xinjie Wang, Fuling Zhou
Journal: Nat Commun
PubMed ID: 38866774
Doi: 10.1038/s41467-024-49414-7
Products & Services: Gene Synthesis   
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria
Authors: Hunter L Abrahamsen, Tristan C Sanford, Casie E Collamore, Bronte A Johnstone, Michael J Coyne, Leonor García-Bayona, Michelle P Christie, Jordan C Evans, Allison J Farrand, Katia Flores, Craig J Morton, Michael W Parker, Laurie E Comstock, Rodney K Tweten
Journal: Nat Commun
PubMed ID: 38866748
Doi: 10.1038/s41467-024-49103-5
Products & Services: Recombinant Proteins   
OsNLP3 enhances grain weight and reduces grain chalkiness in rice
Authors: Liang-Qi Sun, Yu Bai, Jie Wu, Shi-Jun Fan, Si-Yan Chen, Zheng-Yi Zhang, Jin-Qiu Xia, Shi-Mei Wang, Yu-Ping Wang, Peng Qin, Shi-Gui Li, Ping Xu, Zhong Zhao, Cheng-Bin Xiang, Zi-Sheng Zhang
Journal: Plant Commun
PubMed ID: 38853433
Doi: 10.1016/j.xplc.2024.100999
Products & Services: Recombinant Proteins   
SepM mutation in Streptococcus mutans clinical isolates and related function analysis
Authors: Shanshan Liu, Yidan Shao, Zhenzhen Zhang, Wen Xu, Yudong Liu, Kai Zhang, Li Xu, Qingwei Zheng, Yu Sun
Journal: BMC Oral Health
PubMed ID: 38918777
Doi: 10.1186/s12903-024-04436-x
Products & Services: Gene Synthesis   
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2-STAT3 pathway
Authors: Jiahua Yang, Xuechuan Li, Shili Chen, Guoqiang Li, Peng Pu, Yang Yang, Wenguang Wu, Yajun Geng, Yingbin Liu
Journal: Cancer Lett
PubMed ID: 38942137
Doi: 10.1016/j.canlet.2024.217067
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M tuberculosis PrrA binds the dosR promoter and regulates mycobacterial adaptation to hypoxia
Authors: Yannik A Haller, Jiapei Jiang, Zijian Wan, Alexia Childress, Shaopeng Wang, Shelley E Haydel
Journal: Tuberculosis (Edinb)
PubMed ID: 38885567
Doi: 10.1016/j.tube.2024.102531
Products & Services: Custom Vector Construction   
Immuno-Microbial Signature of Vaccine-Induced Immunity against SARS-CoV-2
Authors: Lesley Umeda, Amada Torres, Braden P Kunihiro, Noelle C Rubas, Riley K Wells, Krit Phankitnirundorn, Rafael Peres, Ruben Juarez, Alika K Maunakea
Journal: Vaccines (Basel)
PubMed ID: 38932366
Doi: 10.3390/vaccines12060637
Products & Services: Gene Synthesis   
The Gene Network That Regulates Head Organizer Activity in Is Differentially Regulated in Epidermis and Gastrodermis
Authors: Laura Iglesias Ollé, Chrystelle Perruchoud, Paul Gerald Layague Sanchez, Matthias Christian Vogg, Brigitte Galliot
Journal: Biomedicines
PubMed ID: 38927481
Doi: 10.3390/biomedicines12061274
Products & Services: DNA Sequencing   
Identification of a human type XVII collagen fragment with high capacity for maintaining skin health
Authors: Xinglong Wang, Shuyao Yu, Ruoxi Sun, Kangjie Xu, Kun Wang, Ruiyan Wang, Junli Zhang, Wenwen Tao, Shangyang Yu, Kai Linghu, Xinyi Zhao, Jingwen Zhou
Journal: Synth Syst Biotechnol
PubMed ID: 38911060
Doi: 10.1016/j.synbio.2024.06.001
Products & Services: Gene Synthesis   
A novel BSL-2 Lassa virus reverse genetics system modelling the complete viral life cycle
Authors: Xiaoyou Hu, Xu Bai, Fangling Tian, Yifan Xing, Yi Shi, Yimin Tong, Jin Zhong
Journal: Emerg Microbes Infect
PubMed ID: 38747061
Doi: 10.1080/22221751.2024.2356149
An optimized and robust workflow for quantifying the canonical histone ubiquitination marks H2AK119ub and H2BK120ub by LC-MS/MS
Authors: Mariana Lopes, Peder J Lund, Benjamin A Garcia
Journal: biorxiv
PubMed ID: 38915586
Doi: 10.1101/2024.06.11.596744
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Metabolic Engineering of for Production of Canthaxanthin, Zeaxanthin, and Astaxanthin
Authors: Peerada Promdonkoy, Akaraphol Watcharawipas, Suriyaporn Bubphasawan, Kitisak Sansatchanon, Nattida Suwanakitti, Kanokarn Kocharin, Weerawat Runguphan
Journal: J Fungi (Basel)
PubMed ID: 38921419
Doi: 10.3390/jof10060433
Products & Services: Codon Optimization   
Distance tuneable integral membrane protein containing floating bilayers directed self-assembly
Authors: Stephen C L Hall, David J Hardy, Éilís C Bragginton, Hannah Johnston, Tudor Onose, Rachel Holyfield, Pooja Sridhar, Timothy J Knowles, Luke A Clifton
Journal: Nanoscale
PubMed ID: 38940744
Doi: 10.1039/d3nr04622b
Recombinant Art v401 protein produces immunological tolerance by subcutaneous immunotherapy in a wormwood pollen-driven allergic asthma female mouse model
Authors: Tao Wang, Jiaoni Chi, Zhimin Li, Yue Zhang, Yaojun Wang, Ming Ding, Bin Zhou, JiaChen Gui, Qiang Li
Journal: PLoS ONE
PubMed ID: 38941291
Doi: 10.1371/journal.pone.0280418
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IMT030122, A novel engineered EpCAM/CD3/4-1BB tri-specific antibody, enhances T-cell recruitment and demonstrates anti-tumor activity in mouse models of colorectal cancer
Authors: Jianbo Shen, Niliang Qian, Guili Xu, Xiaoqian Dou, Ying An, Cuima Yang, Yujie Liu, Yunhui Liu, Xiujie Pan, Jingjing Wang, Guijun Bai, Hao Chen, Xiaolin Zhu, Xin Gao, Guoxiong Zhou, Qinzhi Xu
Journal: Int Immunopharmacol
PubMed ID: 38878486
Doi: 10.1016/j.intimp.2024.112424
Single missense mutations in Vi capsule synthesis genes confer hypervirulence to Salmonella Typhi
Authors: Gi Young Lee, Jeongmin Song
Journal: Nat Commun
PubMed ID: 38898034
Doi: 10.1038/s41467-024-49590-6
Products & Services: Recombinant Proteins   
Plasmodium vivax serological exposure markers: PvMSP1-42-induced humoral and memory B-cell response generates long-lived antibodies
Authors: Feng Lu, Jiahui Xu, Yaobao Liu, Zhenyu Ren, Junhu Chen, Weijuan Gong, Yi Yin, Yinyue Li, Li Qian, Xinlong He, Xiu Han, Zhijie Lin, Jingyuan Lu, Wenwen Zhang, Jiali Liu, Didier Menard, Eun-Taek Han, Jun Cao
Journal: PLoS Pathog
PubMed ID: 38941356
Doi: 10.1371/journal.ppat.1012334
Monoterpene-chalcone conjugates and diarylheptanoids isolated from the seeds of Alpinia katsumadai Hayata with cytotoxic activity
Authors: Hua-Lin You, Bo Zhou, Meng-Jia Guo, Xin-Man Zhao, Xiao-Long Li, Xiang-Chun Shen, Nen-Ling Zhang
Journal: Phytochemistry
PubMed ID: 38945281
Doi: 10.1016/j.phytochem.2024.114197
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A 14-amino acid cationic peptide Bolespleenin from the marine fish mudskipper Boleophthalmus pectinirostris exhibiting potent antimicrobial activity and therapeutic potential
Authors: Yuqi Bai, Weibin Zhang, Wenbin Zheng, Xin-Zhan Meng, Yingyi Duan, Chang Zhang, Fangyi Chen, Ke-Jian Wang
Journal: Biochem Pharmacol
PubMed ID: 38852647
Doi: 10.1016/j.bcp.2024.116344
Products & Services: Catalog Peptides   
The role of MASP1 in the complement system and expression characteristics in response to GCRV infection in grass carp
Authors: Yuling Wei, Zhao Lv, Tiaoyi Xiao, Zongjun Du
Journal: Fish Shellfish Immunol
PubMed ID: 38901682
Doi: 10.1016/j.fsi.2024.109712
Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy
Authors: Vadim A Klenchin, Natasha M Clark, Nida K Keles, Saverio Capuano, Rosemarie Mason, Guangping Gao, Aimee Broman, Emek Kose, Taina T Immonen, Christine M Fennessey, Brandon F Keele, Jeffrey D Lifson, Mario Roederer, Matthew R Gardner, David T Evans
Journal: biorxiv
PubMed ID: 38895320
Doi: 10.1101/2024.05.30.593694
Products & Services: Codon Optimization   
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein
Authors: Qi Yang, Bao Xue, Fengjiang Liu, Yongzhi Lu, Jielin Tang, Mengrong Yan, Qiong Wu, Ruyi Chen, Anqi Zhou, Lijie Liu, Junjun Liu, Changbin Qu, Qingxin Wu, Muqing Fu, Jiayi Zhong, Jianwei Dong, Sijie Chen, Fan Wang, Yuan Zhou, Jie Zheng, Wei Peng, Jinsai Shang, Xinwen Chen
Journal: Signal Transduct Target Ther
PubMed ID: 38853183
Doi: 10.1038/s41392-024-01858-5
Products & Services: Catalog Peptides   
Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging
Authors: Seokjo Kang, Emily Y Ko, Amelia E Andrews, Juliana E Shin, Karina J Nance, Pijus K Barman, Peter S Heeger, Willard M Freeman, Bérénice A Benayoun, Helen S Goodridge
Journal: J Neuroinflammation
PubMed ID: 38840206
Doi: 10.1186/s12974-024-03130-7
Library-Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
Authors: Shenlin Hsiao, Shuanghong Chen, Yanhong Jiang, Qiudao Wang, Yang Yang, Yongrong Lai, Tao Zhong, Jiaoyang Liao, Yuxuan Wu
Journal: Adv Sci (Weinh)
PubMed ID: 38874509
Doi: 10.1002/advs.202309004
Products & Services: Molecular Biology Reagents   
Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension
Authors: Shan-Shan Zhang, Lance Larrabee, Andrew H Chang, Sapna Desai, Lisa Sloan, Xin Wang, Yixuan Wu, Nazia Parvez, Karen Amaratunga, Allison C Hartman, Abby Whitnall, Joseph Mason, Nicholas P Barton, Audrey Y Chu, Jonathan M Davitte, Adam J Csakai, Caitlin Vestal Tibbetts, Audrey E Tolbert, Heather O'Keefe, Jessie Polanco, Joseph Foley, Casey Kmett, Jonathan Kehler, Gabriela Kozejova, Feng Wang, Andrew P Mayer, Patrick Koenig, Davide Foletti, Steven J Pitts, Christine G Schnackenberg
Journal: Sci Rep
PubMed ID: 38851835
Doi: 10.1038/s41598-024-62804-7
Products & Services: Molecular Biology Reagents   
A phage nucleus-associated protein from the jumbophage Churi inhibits bacterial growth through protein translation interference
Authors: Wichanan Wannasrichan, Sucheewin Krobthong, Chase J Morgan, Emily G Armbruster, Milan Gerovac, Yodying Yingchutrakul, Patompon Wongtrakoongate, Jörg Vogel, Chanat Aonbangkhen, Poochit Nonejuie, Joe Pogliano, Vorrapon Chaikeeratisak
Journal: biorxiv
PubMed ID: 38915640
Doi: 10.1101/2024.06.15.599175
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The pigeon circovirus evolution, epidemiology and interaction with the host immune system under One Loft Race rearing conditions
Authors: Tomasz Stenzel, Daria Dziewulska, Ewa Łukaszuk, Joy M Custer, Matthew D De Koch, Simona Kraberger, Arvind Varsani
Journal: Sci Rep
PubMed ID: 38877168
Doi: 10.1038/s41598-024-64587-3
Products & Services: Gene Synthesis   
Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems
Authors: Mehtap Bacioglu, Manuel Schweighauser, Derrick Gray, Sofia Lövestam, Taxiarchis Katsinelos, Annelies Quaegebeur, John van Swieten, Zane Jaunmuktane, Stephen W. Davies, Sjors H. W. Scheres, Michel Goedert, Bernardino Ghetti, and Maria Grazia Spillantini
Journal: Acta Neuropathologica
PubMed ID: 38886865
Doi: 10.1186/s40478-024-01813-z
A new anti-CRISPR gene promotes the spread of drug-resistance plasmids in Klebsiella pneumoniae
Authors: Chunyu Jiang, Chengzhi Yu, Shuyi Sun, Jiajia Lin, Mufeng Cai, Zhenquan Wei, Lingling Feng, Jianhui Li, Yan Zhang, Ke Dong ... Show moreAuthor Notes
Journal: Nucleic Acids Res
PubMed ID: 38888121
Doi: 10.1093/nar/gkae516
Structural basis for an early stage of the photosystem II repair cycle in Chlamydomonas reinhardtii
Authors: Anjie Li, Tingting You, Xiaojie Pang, Yidi Wang, Lijin Tian, Xiaobo Li & Zhenfeng Liu
Journal: Nature Communications
PubMed ID: 38890314
Doi: 10.1038/s41467-024-49532-2
Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)   
Improved protein splicing through viral passaging
Authors: Adam J Hume , Dylan J Deeney , John S Smetana , Jacquelyn Turcinovic , John H Connor , Marlene Belfort , Elke Mühlberger , Christopher W Lennon
Journal: MBio
PubMed ID: 38780266
Doi: 10.1128/mbio.00984-24
Products & Services: Gene Synthesis   Mutagenesis Services   
Heterologous booster vaccination enhances antibody responses to SARS-CoV-2 by improving Tfh function and increasing B-cell clonotype SHM frequency
Authors: Yanli Song, Jiaolei Wang, Zhihui Yang, Changgui Li
Journal: Frontiers in Immunology
Doi: 10.3389/fimmu.2024.1406138
Products & Services: Catalog Peptides   
Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function
Authors: Zichao Zhang , Jing Chen , Rongze Ma , Chongshen Xu , Yunzhe Lu , Jiecan Zhou , Kun Xia , Pengfei Lu
Journal: Adv Sci (Weinh)
PubMed ID: 38884279
Doi: 10.1002/advs.202308822
Products & Services: Recombinant Proteins   
A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and sarbecoviruses
Authors: Yingdan Wang # 1 2, Aihua Hao # 1, Ping Ji # 1, Yunping Ma # 1 3, Zhaoyong Zhang # 4, Jiali Chen 1, Qiyu Mao 1, Xinyi Xiong 4, Palizhati Rehati 1, Yajie Wang 1, Yanqun Wang 4, Yumei Wen 1, Lu Lu 1, Zhenguo Chen 1, Jincun Zhao 5 6, Fan Wu 7, Jinghe Huang 8 9, Lei Sun 10
Journal: Nat Commun
PubMed ID: 38879565
Doi: 10.1038/s41467-024-49096-1
Products & Services: Gene Synthesis   
The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer
Authors: Pengfei Yan , Xi Lin , Lijie Wu , Lu Xu , Fei Li , Junlin Liu , Fei Xu
Journal: Nat Commun
PubMed ID: 38898050
Doi: 10.1038/s41467-024-49625-y
Products & Services: Gene Synthesis   
Molecular recognition of the atypical chemokine-like peptide GPR15L by its cognate receptor GPR15
Authors: Zhongyuan Zhang , You Zheng , Lu Xu , Yang Yue , Kexin Xu , Fei Li 1, Fei Xu
Journal: Cell Discov
PubMed ID: 38918398
Doi: 10.1038/s41421-024-00698-5
Products & Services: Peptide Synthesis   
Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering
Authors: Mona Alharbi, Andrew Lai, Nihar Godbole, Dominic Guanzon, Soumyalekshmi Nair, Felipe Zuñiga, Alexander Quinn, Mengliu Yang, Sherry Y Wu, Carlos Salomon
Journal: Int J Cancer
PubMed ID: 38848494
Doi: 10.1002/ijc.35055
Products & Services: Molecular Biology Reagents   
Electrophysiological Impact of SARS-CoV-2 Envelope Protein in U251 Human Glioblastoma Cells: Possible Implications in Gliomagenesis?
Authors: Lorenzo Monarca, Francesco Ragonese, Andrea Biagini, Paola Sabbatini, Matteo Pacini, Alessandro Zucchi, Roberta Spaccapelo, Paola Ferrari, Andrea Nicolini, Bernard Fioretti
Journal: Int J Mol Sci
PubMed ID: 38928376
Doi: 10.3390/ijms25126669
Products & Services: Gene Synthesis   
Baculovirus surface display of a chimeric E-NS1 protein of YFV protects against YFV infection
Authors: Carla Tomatis, María Florencia Ferrer, Silvia Aquila, Pablo Daniel Thomas, Paula Nazarena Arrías, Leticia Ferrelli, Matías Pidre, Victor Romanowski, Eugenio Antonio Carrera Silva, Ricardo Martín Gómez
Journal: Vaccine
PubMed ID: 38852036
Doi: 10.1016/j.vaccine.2024.06.013
Products & Services: Immunoassay Development Services   
miR-520e and its promoter region DNA methylation as potential biomarkers in atherosclerosis
Authors: Mimi Mu, Gao Liu, Xiaoyu Ding, Lijun Xue, Dandan Li, Yunhua Zhu, Nan Zhang, Jia Wu, Junjun Wang
Journal: Biochem Cell Biol
PubMed ID: 38917487
Doi: 10.1139/bcb-2023-0326
Products & Services: Molecular Biology Reagents   
Scaffold-enabled high-resolution cryo-EM structure determination of RNA
Authors: Daniel B Haack, Boris Rudolfs, Shouhong Jin, Kevin M Weeks, Navtej Toor
Journal: biorxiv
PubMed ID: 38915706
Doi: 10.1101/2024.06.10.598011
Products & Services: Molecular Biology Reagents   
Synthetic Peptides Elicit Humoral Response against Porcine Reproductive and Respiratory Syndrome Virus in Swine
Authors: Francisco Perez-Duran, Fernando Calderon-Rico, Luis Enrique Franco-Correa, Alicia Gabriela Zamora-Aviles, Roberto Ortega-Flores, Daniel Durand-Herrera, Alejandro Bravo-Patiño, Ricarda Cortes-Vieyra, Ilane Hernandez-Morales, Rosa Elvira Nuñez-Anita
Journal: Vaccines (Basel)
PubMed ID: 38932381
Doi: 10.3390/vaccines12060652
Products & Services: Catalog Peptides   
mRNA Vaccine for Alzheimer's Disease: Pilot Study
Authors: Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan
Journal: Vaccines (Basel)
PubMed ID: 38932388
Doi: 10.3390/vaccines12060659
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Androgen-responsive FOXP4 is a target for endometrial carcinoma
Authors: Kayo Kayahashi, Mahadi Hasan, Anowara Khatun, Susumu Kohno, Jumpei Terakawa, Shin-Ichi Horike, Natsumi Toyoda, Ayumi Matsuoka, Takashi Iizuka, Takeshi Obata, Masanori Ono, Yasunari Mizumoto, Chiaki Takahashi, Hiroshi Fujiwara, Takiko Daikoku
Journal: Commun Biol
PubMed ID: 38890503
Doi: 10.1038/s42003-024-06433-w
Products & Services: Molecular Biology Reagents   
Development of GPC3-CAR-NK cells and optimization as a therapy for HCC
Authors: Bihui Cao, Qianqian Ni, Zhuxin Chen, Shuo Yang, Xinkui Zhang, Haotao Su, Zhenfeng Zhang, Qi Zhao, Xiaolan Zhu, Manting Liu
Journal: J Leukoc Biol
PubMed ID: 38922297
Doi: 10.1093/jleuko/qiae144
Products & Services: Molecular Biology Reagents   
Selenium nanoparticles enhance mucosal immunity against Mycobacterium bovis infection
Authors: Xin Ge, Zhengmin Liang, Kui Li, Yuhui Dong, Yuanzhi Wang, Yiduo Liu, ZiYi Liu, Haoran Wang, Yue Nan, SiYan Chen, Lin Li, Yanbin Guo, Xiangmei Zhou
Journal: Int Immunopharmacol
PubMed ID: 38878484
Doi: 10.1016/j.intimp.2024.112384
Products & Services: Molecular Biology Reagents   
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics
Authors: Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
Journal: Nat Commun
PubMed ID: 38942756
Doi: 10.1038/s41467-024-49233-w
Products & Services: Gene Synthesis   
Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels
Authors: Emily Mantlo, Jessie D Trujillo, Natasha N Gaudreault, Igor Morozov, Charles E Lewis, Franco Matias-Ferreyra, Chester McDowell, Dashzeveg Bold, Taeyong Kwon, Konner Cool, Velmurugan Balaraman, Daniel Madden, Bianca Artiaga, Jayme Souza-Neto, Jeffrey B Doty, Mariano Carossino, Udeni Balasuriya, William C Wilson, Nikolaus Osterrieder, Lisa Hensley, Juergen A Richt
Journal: Emerg Microbes Infect
PubMed ID: 38712637
Doi: 10.1080/22221751.2024.2352434
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Effect of TIMPs and Their Minimally Engineered Variants in Blocking Invasion and Migration of Brain Cancer Cells
Authors: Elham Taheri, Maryam Raeeszadeh-Sarmazdeh
Journal: biorxiv
PubMed ID: 38895489
Doi: 10.1101/2024.06.05.597644
Products & Services: Catalog Peptides   
Arboviruses antagonize insect Toll antiviral immune signaling to facilitate the coexistence of viruses with their vectors
Authors: Dongsheng Jia, Guozhong Luo, Heran Guan, Tingting Yu, Xinyan Sun, Yu Du, Yiheng Wang, Hongyan Chen, Taiyun Wei
Journal: PLoS Pathog
PubMed ID: 38865374
Doi: 10.1371/journal.ppat.1012318
Products & Services: Polyclonal Antibody Services   
Molecular determinants of olfactory receptor activation: Comparative analysis of Olfr205 and Olfr740 family member responses to indole
Authors: Guangyao Li, Li Wang, Fangzhou Ye, Shengju Li, Hongmeng Yu
Journal: Arch Biochem Biophys
PubMed ID: 38880319
Doi: 10.1016/j.abb.2024.110061
Products & Services: Molecular Biology Reagents   
Epitope-specific antibody fragments block aggregation of AGelD187N, an aberrant peptide in gelsolin amyloidosis
Authors: Laura Leimu, Patrik Holm, Anna Gąciarz, Oskar Haavisto, Stuart Prince, Ullamari Pesonen, Tuomas Huovinen, Urpo Lamminmäki
Journal: J Biol Chem
PubMed ID: 38944121
Doi: 10.1016/j.jbc.2024.107507
Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity
Authors: Siddhi Omkar, Courtney Shrader, Joel R Hoskins, Jake T Kline, Megan M Mitchem, Luca Fornelli, Sue Wickner, Andrew W Truman
Journal: biorxiv
PubMed ID: 38915721
Doi: 10.1101/2024.06.13.598777
Products & Services: Molecular Biology Reagents   
Identification of a novel glycoside hydrolase family 8 xylanase from Deinococcus geothermalis and its application at low temperatures
Authors: Tingting Wang, Min Lin, Yongliang Yan, Shijie Jiang, Qilin Dai, Zhengfu Zhou, Jin Wang
Journal: Arch Microbiol
PubMed ID: 38884653
Doi: 10.1007/s00203-024-04055-8
Transgenic Soybean for Production of Thermostable α-Amylase
Authors: Zhenyan Cao, Ye Jiang, Jiajie Li, Ting Zheng, Chaoyang Lin, Zhicheng Shen
Journal: Plants (Basel)
PubMed ID: 38891347
Doi: 10.3390/plants13111539
Products & Services: Recombinant Proteins   
Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in
Authors: Marcus Foo, Luke R Frietze, Behnam Enghiad, Yujie Yuan, Christopher D Katanski, Huimin Zhao, Tao Pan
Journal: ACS Chem Biol
PubMed ID: 38912606
Doi: 10.1021/acschembio.4c00278
Products & Services: Gene Synthesis   
H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs
Authors: Fei-Fei Ge, Li-Pin Shen, De-Quan Yang, Xian-Cao Yang, Xin Li, Hai-Xiao Shen, Jian Wang, Shixin Huang
Journal: Microbiol Spectr
PubMed ID: 38874403
Doi: 10.1128/spectrum.00445-24
Products & Services: Gene Synthesis   
Auxin resistant 2 and short hypocotyl 2 regulate cotton fiber initiation and elongation
Authors: Fei Jin, Liping Zhu, Liyong Hou, Hongbin Li, Ling Li, Guanghui Xiao
Journal: Plant Physiol
PubMed ID: 38527791
Doi: 10.1093/plphys/kiae183
Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants
Authors: Lei He, Qian Wu, Zhaoyong Zhang, Lingling Chen, Kuai Yu, Leibin Li, Qiong Jia, Yanqun Wang, Jianqiang Ni, Chuanbin Wang, Qi Li, Xinyan Zhai, Jincun Zhao, Yuliang Liu, Ruiwen Fan, Yi-Ping Li
Journal: Mol Pharm
PubMed ID: 38920116
Doi: 10.1021/acs.molpharmaceut.4c00165
Interleukin-1 beta (IL-1β) as adjuvant enhances the immune effects of Aeromonas veronii inactivated vaccine in largemouth bass (Micropterus salmoides)
Authors: Ze-Sheng Zhang, Heng-Chu Ren, Xie Gu, Qian-Rong Liang, Hui Fei, Yu-Hong Yang, Shun Yang, Liang-Yin He, Li-Li Liu
Journal: Int J Biol Macromol
PubMed ID: 38876231
Doi: 10.1016/j.ijbiomac.2024.133135
Products & Services: Molecular Biology Reagents   
Exploring a novel GH13_5 α-amylase from Jeotgalibacillus malaysiensis D5 for raw starch hydrolysis
Authors: Nurfatini Radzlin, Mohd Shukuri Mohamad Ali, Kian Mau Goh, Amira Suriaty Yaakop, Iffah Izzati Zakaria, Ummirul Mukminin Kahar
Journal: AMB Express
PubMed ID: 38874807
Doi: 10.1186/s13568-024-01722-3
Products & Services: Gene Synthesis   
Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome
Authors: Boyang Zhao, Zhongzheng Cao, Yi Zheng, Phuong Nguyen, Alisa Bowen, Robert H Edwards, Robert M Stroud, Yi Zhou, Menno Van Lookeren Campagne, Fei Li
Journal: Nat Commun
PubMed ID: 38918376
Doi: 10.1038/s41467-024-49614-1
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Assessing Predictive Value of SARS-CoV-2 Epitope-Specific CD8 T-Cell Response in Patients with Severe Symptoms
Authors: Cristina Martín-Martín, Estefanía Salgado Del Riego, Jose R Vidal Castiñeira, Maria Soledad Zapico-Gonzalez, Mercedes Rodríguez-Pérez, Viviana Corte-Iglesias, Maria Laura Saiz, Paula Diaz-Bulnes, Dolores Escudero, Beatriz Suárez-Alvarez, Carlos López-Larrea
Journal: Vaccines (Basel)
PubMed ID: 38932408
Doi: 10.3390/vaccines12060679
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Functional characterization of a cystatin A from the bat Myotis davidii
Authors: Gabriel Cerqueira Alves Costa, Ricardo Jose Soares Torquato, Vinícius de Morais Gomes, Lívia Rosa-Fernandes, Giuseppe Palmisano, Aparecida Sadae Tanaka
Journal: Comp Biochem Physiol B Biochem Mol Biol
PubMed ID: 38936799
Doi: 10.1016/j.cbpb.2024.111003
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Production of norovirus-, rotavirus-, and enterovirus-like particles in insect cells is simplified by plasmid-based expression
Authors: Vili Lampinen, Stina Gröhn, Nina Lehmler, Minne Jartti, Vesa P Hytönen, Maren Schubert, Minna M Hankaniemi
Journal: Sci Rep
PubMed ID: 38937523
Doi: 10.1038/s41598-024-65316-6
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Cost-Efficient Expression of Human Cardiac Myosin Heavy Chain in C2C12 Cells with a Non-Viral Transfection Reagent
Authors: Albin E Berg, Lok Priya Velayuthan, Alf Månsson, Marko Ušaj
Journal: Int J Mol Sci
PubMed ID: 38928453
Doi: 10.3390/ijms25126747
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CircVIRMA enhances cell malignant behavior by governing the miR-452-5p/CREBRF pathway in cervical cancer
Authors: Chengluo Hao, Jianjun Han, Kechao Xiang, Yun Wang, Xiangrui Chen, Chen Yang, Ailin Liang, Li Jia
Journal: Naunyn Schmiedebergs Arch Pharmacol
PubMed ID: 38850300
Doi: 10.1007/s00210-024-03159-8
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Circ_002033 Regulates Proliferation, Apoptosis, and Oxidative Damage of Bovine Mammary Epithelial Cells via the miR-199a-5p-MAP3K11 Axis in Heat Stress
Authors: Hanfang Zeng, Shujie Li, Haomiao Chang, Yunfei Zhai, Haihui Wang, Hantong Weng, Zhaoyu Han
Journal: J Agric Food Chem
PubMed ID: 38869955
Doi: 10.1021/acs.jafc.3c09835
Immune responses and reinfection of SARS-CoV-2 Omicron variant in patients with lung cancer
Authors: Chen Chen, Xiaoyun Zhou, Xiaoxing Gao, Ruili Pan, Qi He, Xiaobei Guo, Siyuan Yu, Na Wang, Qian Zhao, Mengzhao Wang, Yan Xu, Xiaohong Han
Journal: Int J Cancer
PubMed ID: 38837354
Doi: 10.1002/ijc.35038
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Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp
Authors: Maria A Schumacher, Rajiv R Singh, Raul Salinas
Journal: Nucleic Acids Res
PubMed ID: 38832628
Doi: 10.1093/nar/gkae459
NbPTR1 confers resistance against Pseudomonas syringae pv actinidiae in kiwifruit
Authors: Shin-Mei Yeh, Minsoo Yoon, Sidney Scott, Abhishek Chatterjee, Lauren M Hemara, Ronan K Y Chen, Tianchi Wang, Kerry Templeton, Erik H A Rikkerink, Jay Jayaraman, Cyril Brendolise
Journal: Plant Cell Environ
PubMed ID: 38899426
Doi: 10.1111/pce.15002
Products & Services: Codon Optimization   
Double promoter and tandem gene strategy for efficiently expressing recombinant FGF21
Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang, Xianlong Ye
Journal: Microb Cell Fact
PubMed ID: 38867280
Doi: 10.1186/s12934-024-02447-5
Products & Services: Gene Synthesis   
Development of a Ferritin Protein Nanoparticle Vaccine with PRRSV GP5 Protein
Authors: Xinjian Chang, Jun Ma, Yanrong Zhou, Shaobo Xiao, Xun Xiao, Liurong Fang
Journal: Viruses
PubMed ID: 38932282
Doi: 10.3390/v16060991
Products & Services: Molecular Biology Reagents   
Discovery, characterization, and comparative analysis of new UGT72 and UGT84 family glycosyltransferases
Authors: Tuo Li, Annika J E Borg, Leo Krammer, Hansjörg Weber, Rolf Breinbauer, Bernd Nidetzky
Journal: Commun Chem
PubMed ID: 38942997
Doi: 10.1038/s42004-024-01231-1
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DNA mismatch and damage patterns revealed by single-molecule sequencing
Authors: Mei Hong Liu, Benjamin M Costa, Emilia C Bianchini, Una Choi, Rachel C Bandler, Emilie Lassen, Marta Grońska-Pęski, Adam Schwing, Zachary R Murphy, Daniel Rosenkjær, Shany Picciotto, Vanessa Bianchi, Lucie Stengs, Melissa Edwards, Nuno Miguel Nunes, Caitlin A Loh, Tina K Truong, Randall E Brand, Tomi Pastinen, J Richard Wagner, Anne-Bine Skytte, Uri Tabori, Jonathan E Shoag, Gilad D Evrony
Journal: Nature
PubMed ID: 38867045
Doi: 10.1038/s41586-024-07532-8
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IgE-Mediated Sensitization to Blo t 21 and Blo t 5 Is Associated With Asthma in the Tropics: A Case-Control Study
Authors: J Zakzuk, K Donado, E Mondol, V Marrugo, R Regino, J F López, K Hernandez, D Mercado, R Dennis, L Puerta, L Caraballo
Journal: J Investig Allergol Clin Immunol
PubMed ID: 38888580
Doi: 10.18176/jiaci.0892
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C-terminal Poly-histidine Tags Alter Escherichia coli Polyphosphate Kinase Activity and Susceptibility to Inhibition
Authors: Marvin Q Bowlin, Avery D Lieber, Abagail R Long, Michael J Gray
Journal: J Mol Biol
PubMed ID: 38866092
Doi: 10.1016/j.jmb.2024.168651
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A soybean cyst nematode suppresses microbial plant symbionts using a lipochitooligosaccharide-hydrolysing enzyme
Authors: Wei Chen, Di Wang, Shaoyong Ke, Yangrong Cao, Wensheng Xiang, Xiaoli Guo, Qing Yang
Journal: Nat Microbiol
PubMed ID: 38886584
Doi: 10.1038/s41564-024-01727-5
Products & Services: Codon Optimization   
Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2
Authors: J Wouter Beugelink, Els Sweep, Bert J C Janssen, Joost Snijder, Matti F Pronker
Journal: J Mol Biol
PubMed ID: 38852931
Doi: 10.1016/j.jmb.2024.168649
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Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice
Authors: Szu-Hsien Sam Wu, Somi Kim, Heetak Lee, Ji-Hyun Lee, So-Yeon Park, Réka Bakonyi, Isaree Teriyapirom, Natalia Hallay, Sandra Pilat-Carotta, Hans-Christian Theussl, Jihoon Kim, Joo-Hyeon Lee, Benjamin D Simons, Jong Kyoung Kim, Gabriele Colozza, Bon-Kyoung Koo
Journal: Nat Commun
PubMed ID: 38862535
Doi: 10.1038/s41467-024-49382-y
Products & Services: Molecular Biology Reagents   
New wheat straw fermentation feed: recombinant efficient degradation of lignocellulose and increase feed protein
Authors: Xihua Chen, Xiaoyu Liang, Na Shi, Lu He, Yi Ma, Daochen Zhu, Zhong Ni, Huayou Chen
Journal: Prep Biochem Biotechnol
PubMed ID: 38824495
Doi: 10.1080/10826068.2024.2353637
Products & Services: Gene Synthesis   
TnpB homologues exapted from transposons are RNA-guided transcription factors
Authors: Tanner Wiegand, Florian T Hoffmann, Matt W G Walker, Stephen Tang, Egill Richard, Hoang C Le, Chance Meers, Samuel H Sternberg
Journal: Nature
PubMed ID: 38926585
Doi: 10.1038/s41586-024-07598-4
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system
Authors: Olawale G Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M Lange, Cristian Polo Rivera, Tom D Deegan, Yinchen Chen, Melanie Wightman, Rachel Toth, Karim P M Labib, Sebastian Mathea, Neil Ranson, Rubén Fernández-Busnadiego, Miratul M K Muqit
Journal: SCIENCE ADVANCES
PubMed ID: 38848361
Doi: 10.1126/sciadv.adn7191
Understanding the Phase Behavior of a Multistimuli-Responsive Elastin-like Polymer: Insights from Dynamic Light Scattering Analysis
Authors: Peter C Swanson, Galen P Arnold, Carolyn E Curley, Savannah C Wakita, Jeffery D V Waters, Eva Rose M Balog
Journal: J Phys Chem B
PubMed ID: 38830627
Doi: 10.1021/acs.jpcb.4c00070
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Cholesterol neutralized vemurafenib treatment by promoting melanoma stem‑like cells via its metabolite 27‑hydroxycholesterol
Authors: Xiaohong Wang, Feiliang Zhong, Tingting Chen, Hongbo Wang, Weifang Wang, Hongkai Jin, Chouyang Li, Xuan Guo, Ying Liu, Yu Zhang, Bo Li
Journal: Cell Mol Life Sci
PubMed ID: 38775844
Doi: 10.1007/s00018-024-05267-3
Engineered probiotics with sustained release of interleukin-2 for the treatment of inflammatory bowel disease after oral delivery
Authors: Maoyi Li, Nanhui Liu, Jiafei Zhu, Yumin Wu, Le Niu, Yi Liu, Linfu Chen, Boxiong Bai, Yu Miao, Yang Yang, Qian Chen
Journal: Biomaterials
PubMed ID: 38735180
Doi: doi.org/10.1016/j.biomaterials.2024.122584
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Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry
Authors: Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J Gibbings, Laura Trinkle-Mulcahy, John W Copeland
Journal: Int J Mol Sci
PubMed ID: 38891874
Doi: 10.3390/ijms25115686
Blue light-mediated gene expression as a promising strategy to reduce antibiotic resistance in Escherichia coli
Authors: Qingwei Jiang, Feng Geng, Juan Shen, Ping Zhu, Zhaoxin Lu, Fengxia Lu, Libang Zhou
Journal: Biotechnol J
PubMed ID: 38719589
Doi: 10.1002/biot.202400023
Effect of Free Cysteine Residues to Serine Mutation on Cellodextrin Phosphorylase
Authors: Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi
Journal: J Appl Glycosci (1999)
PubMed ID: 38863949
Doi: 10.5458/jag.jag.JAG-2023_0011
Products & Services: Molecular Biology Reagents   
Micro-and nano-plastics induce kidney damage and suppression of innate immune function in zebrafish (Danio rerio) larvae
Authors: Hui Yang, Jian Ju, Yuting Wang, Zhu Zhu, Wenyan Lu, Yingying Zhang
Journal: Sci Total Environ
PubMed ID: 38703841
Doi: 10.1016/j.scitotenv.2024.172952
Products & Services: Catalog Antibody   
Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2
Authors: Dan Gao, Wei-Wei Yi, Bo Liu, Cong-En Zhang, Cui-Cui Yang, Li Zeng, Lin Li, Guangbin Luo, Lan Zhang, Zhen-Yu Ju, Jia-Bo Wang
Journal: J Adv Res
PubMed ID: 38704089
Doi: 10.1016/j.jare.2024.04.027
CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma
Authors: Lin Tan, Han Zhang, Yun Ding, Yangyun Huang, Daqiang Sun
Journal: Sci Rep
PubMed ID: 38755183
Doi: 10.1038/s41598-024-61804-x
A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy
Authors: Dan A Tudorica, Bishal Basak, Alexia S Puerta Cordova, Grace Khuu, Kevin Rose, Michael Lazarou, Erika L F Holzbaur, James H Hurley
Journal: J Cell Biol
PubMed ID: 38728007
Doi: 10.1083/jcb.202309015
Products & Services: Molecular Biology Reagents   
Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4
Authors: Jianyao Zeng, Yuan Fang, Zixuan Zhang, Zhenzhen Lv, Xiaodie Wang, Qian Huang, Zhidan Tian, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Jing Yu, Tao Liu, Qijun Qian
Journal: Oncogene
PubMed ID: 38806619
Doi: 10.1038/s41388-024-03066-5
Post-transcriptional regulation of the T-box gene midline via the 3'UTR in Drosophila is complex and cell and tissue-dependent
Authors: Kalpana Makhijani, Jordan Mar, Ivana Gaziova, Krishna Moorthi Bhat
Journal: Genetics
PubMed ID: 38805187
Doi: 10.1093/genetics/iyae087
Products & Services: Molecular Biology Reagents   
Identification and characterization of calcium binding protein, spermatid-associated 1 (CABS1)# in selected human tissues and fluids
Authors: Eduardo Reyes-Serratos, Joy Ramielle L Santos, Lakshmi Puttagunta, Stephen J Lewis, Mechiko Watanabe, Aron Gonshor, Robert Buck, A Dean Befus, Marcelo Marcet-Palacios
Journal: PLoS ONE
PubMed ID: 38753592
Doi: 10.1371/journal.pone.0301855
EDA2R knockdown alleviates myocardial ischemia/reperfusion injury through inhibiting the activation of the NF-κB signaling pathway
Authors: Zhi-Hui Guan, Di Yang, Yi Wang, Jia-Bin Ma, Guo-Nian Wang
Journal: Exp Anim
PubMed ID: 38797667
Doi: 10.1538/expanim.24-0020
Products & Services: Molecular Biology Reagents   
Filtered Saliva for Rapid and Accurate Analyte Detection for POC Diagnostics
Authors: Nadia Farsaeivahid, Christian Grenier, Ming L Wang
Journal: Diagnostics (Basel)
PubMed ID: 38893615
Doi: 10.3390/diagnostics14111088
BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation
Authors: Swati Garg, Wei Ni, Basudev Chowdhury, Ellen L Weisberg, Martin Sattler, James D Griffin
Journal: Cell Death Differ
PubMed ID: 38816579
Doi: 10.1038/s41418-024-01306-5
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