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MitoNEET prevents iron overload-induced insulin resistance in H9c2 cells through regulation of mitochondrial iron
Authors: Eddie Tam, Hye K Sung, Gary Sweeney
Journal: J Cell Physiol
PubMed ID: 37269467
Doi: 10.1002/jcp.31044
Products & Services: Molecular Biology Reagents   
Chimeric antigen receptor T cells targeting FcRH5 provide robust tumour-specific responses in murine xenograft models of multiple myeloma
Authors: Dongpeng Jiang, Haiwen Huang, Huimin Qin, Koukou Tang, Xiangru Shi, Tingting Zhu, Yuqing Gao, Ying Zhang, Xiaopeng Tian, Jianhong Fu, Weiwei Qu, Weilan Cai, Yang Xu, Depei Wu, Jianhong Chu
Journal: Nat Commun
PubMed ID: 37339964
Doi: 10.1038/s41467-023-39395-4
Products & Services: Recombinant Proteins   
Recombinant Bacillus Calmette-Guérin Expressing SARS-CoV-2 Chimeric Protein Protects K18-hACE2 Mice against Viral Challenge
Authors: Fábio Mambelli, Fábio V Marinho, Juvana M Andrade, Ana C V S C de Araujo, Rodrigo P F Abuna, Victor M R Fabri, Bruno P O Santos, João S da Silva, Mariana T Q de Magalhães, E Jane Homan, Luciana C C Leite, Greicy B M Dias, Nicoli Heck, Daniel A G B Mendes, Daniel S Mansur, André Báfica, Sergio C Oliveira
Journal: J Immunol
PubMed ID: 37098890
Doi: 10.4049/jimmunol.2200731
Products & Services: Peptide Synthesis   
KRT10 plays an important role in the release of viral genome from endosomes during H9N2 subtype AIV replication in HeLa cells
Authors: Xiangyu Huang, Guihu Yin, Bin Zhou, Yiqin Cai, Jianing Hu, Jingwen Huang, Zili Chen, Qingtao Liu, Xiuli Feng
Journal: Vet Microbiol
PubMed ID: 37406407
Doi: 10.1016/j.vetmic.2023.109824
Engineering BioBricks for Deoxysugar Biosynthesis and Generation of New Tetracenomycins
Authors: Heli Tirkkonen, Katelyn V. Brown, Magdalena Niemczura, Zélie Faudemer, Courtney Brown, Larissa V. Ponomareva, Yosra A. Helmy, Jon S. Thorson, S. Eric Nybo, Mikko Metsä-Ketelä, and Khaled A. Shaaban
Journal: ACS Omega
Doi: 10.1021/acsomega.3c02460
Products & Services: Gene Synthesis   PCR Cloning and Subcloning   
Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists
Authors: Wenjing Sun , Fan Yang , Huanhuan Zhang , Qingning Yuan , Shenglong Ling , Yuanxia Wang , Pei Lv , Zelin Li , Yifan Luo , Dongsheng Liu , Wanchao Yin , Pan Shi , H Eric Xu, Changlin Tian
Journal: Cell Discov .
PubMed ID: 37391393
Doi: 10.1038/s41421-023-00564-w
Products & Services: Peptide Synthesis   
Molecular Quantification and Mutation Detection as Essential Tools for the Clinical Management of Chronic Myeloid Leukemia Patients: Results from a Brazilian Single-Center Study
Authors: Anelis Maria Marin, Denise Kusma Wosniaki, Heloisa Bruna Soligo Sanchuki, Eduardo Cilião Munhoz, Jeanine Marie Nardin, Gabriela Silva Soares, Dhienifer Caroline Espinace, João Samuel de Holanda Farias, Bruna Veroneze, Luiz Felipe Becker, Guilherme Lima Costa, Olair Carlos Beltrame, Jaqueline Carvalho de Oliveira, Geison Cambri, Dalila Luciola Zanette, Mateus Nóbrega Aoki
Journal: Int J Mol Sci
PubMed ID: 37373266
Doi: 10.3390/ijms241210118
Products & Services: Molecular Biology Reagents   
Isolation of recombinant apolipoprotein E4 N-terminal domain by foam fractionation
Authors: Kyle Lethcoe, Colin A Fox, Anouar Hafiane, Robert S Kiss, Robert O Ryan
Journal: Protein Expr Purif
PubMed ID: 37290717
Doi: 10.1016/j.pep.2023.106319
Products & Services: Molecular Biology Reagents   
Inhibition of chitin deacetylases to attenuate plant fungal diseases
Authors: Lin Liu, Yeqiang Xia, Yingchen Li, Yong Zhou, Xiaofeng Su, Xiaojing Yan, Yan Wang, Wende Liu, Hongmei Cheng, Yuanchao Wang, Qing Yang
Journal: Nat Commun
PubMed ID: 37385996
Doi: 10.1038/s41467-023-39562-7
Products & Services: Gene Synthesis   
Structural basis for the binding of DNP and purine nucleotides onto UCP1
Authors: Yunlu Kang, Lei Chen
Journal: Nature
PubMed ID: 37336486
Doi: 10.1038/s41586-023-06332-w
Products & Services: Gene Synthesis   
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability
Authors: Anil Kumar Vijjamarri, Xiao Niu, Matthew D Vandermeulen, Chisom Onu, Fan Zhang, Hongfang Qiu, Neha Gupta, Swati Gaikwad, Miriam L Greenberg, Paul J Cullen, Zhenguo Lin, Alan G Hinnebusch
Journal: Elife
PubMed ID: 37266577
Doi: 10.7554/eLife.85545
Products & Services: PCR Cloning and Subcloning   
Complementary methods for monitoring hole-hole homodimer associated with a WuXiBody-based asymmetric bispecific antibody
Authors: Wanyuan Dong, Yifeng Li
Journal: Protein Expr Purif
PubMed ID: 37271410
Doi: 10.1016/j.pep.2023.106316
Epigenetic Iinsights into the Senescence of Porcine Fetal Fibroblasts induced by Passaging
Authors: Jiaying Bi, Dayu Wang, Fuquan Zhu, Xinyue Lu, Yan Xie, Huijun Liu, Meixia Wang, Xu He, Yuan Jiang, Ke Liu, Mingyue Zhao, Tingzhang Wang, Juan Li
Journal: Cell Cycle
PubMed ID: 37338871
Doi: 10.1080/15384101.2023.2222521
Products & Services: Molecular Biology Reagents   
A MYB activator, DcMYB11c, regulates carrot anthocyanins accumulation in petiole but not taproot
Authors: Ao-Qi Duan, Yuan-Jie Deng, Shan-Shan Tan, Zhi-Sheng Xu, Ai-Sheng Xiong
Journal: Plant Cell Environ
PubMed ID: 37338208
Doi: 10.1111/pce.14653
Products & Services: PCR Cloning and Subcloning   
Circ_PIAS1 Promotes the Apoptosis of ALV-J Infected DF1 Cells by Up-Regulating miR-183
Authors: Ting Yang , Lingling Qiu , Shihao Chen , Zhixiu Wang , Yong Jiang , Hao Bai , Yulin Bi , Guohong Chen , Guobin Chang
Journal: Genes (Basel) .
PubMed ID: 37372440
Doi: 10.3390/genes14061260
Cytoplasmic aggregation of mutant FUS causes multistep RNA splicing perturbations in the course of motor neuron pathology
Authors: Alexander P Rezvykh, Aleksey A Ustyugov, Kirill D Chaprov, Ekaterina V Teterina, Vladimir O Nebogatikov, Daria S Spasskaya, Michael B Evgen'ev, Alexey V Morozov, Sergei Yu Funikov
Journal: Nucleic Acids Res
PubMed ID: 37115004
Doi: 10.1093/nar/gkad319
Effects of the deletion and substitution of thioesterase on bacillomycin D synthesis
Authors: Ping Zhang, Ziyan Lv, Zhaoxin Lu, Wenjie Ma, Xiaomei Bie
Journal: Biotechnol Lett
PubMed ID: 37266877
Doi: 10.1007/s10529-023-03373-z
Clostridium perfringens epsilon prototoxin mutant rpETX as a vaccine candidate against enterotoxemia
Authors: Jige Du, Tuanjie Wang, Lei Xu, Cong Wang, Ying Liu, Chenfan Pan, Xiaoyun Chen, Zhen Zhu, Yufeng Luo, Chunsheng Yin
Journal: Vaccine
PubMed ID: 37357076
Doi: 10.1016/j.vaccine.2023.06.044
Products & Services: Molecular Biology Reagents   
Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates
Authors: Steven Boeynaems, Yanniv Dorone, Yanrong Zhuang, Victoria Shabardina, Guozhong Huang, Anca Marian, Garam Kim, Anushka Sanyal, Nesli-Ece Şen, Daniel Griffith, Roberto Docampo, Keren Lasker, Iñaki Ruiz-Trillo, Georg Auburger, Alex S Holehouse, Edor Kabashi, Yi Lin, Aaron D Gitler
Journal: Mol Cell
PubMed ID: 37295429
Doi: 10.1016/j.molcel.2023.05.025
Products & Services: Molecular Biology Reagents   
Revealing the impact of CD70 expression on the manufacture and functions of CAR-70 T-cells based on single-cell transcriptomics
Authors: Jiali Cheng, Yuyan Zhao, Hui Hu, Ling Tang, Yuhao Zeng, Xinyue Deng, Shengnan Ding, An-Yuan Guo, Qing Li, Xiaojian Zhu
Journal: Cancer Immunol Immunother
PubMed ID: 37382633
Doi: 10.1007/s00262-023-03475-7
Comparative assessment of homemade ELISA and lateral flow assay (LFA)in the rapid, specific and sensitive detection of SARS-CoV-2 anti-nucleocapsid protein in sera of Egyptian patients
Authors: Asmaa El-Shershaby, Nahla Hussein, Esraa Ali, Amr El-Hakim, Ashraf Tabll, Mohamed Shaheen, Ibrahim Ali, Mahmoud Elshall, Yasser Shahein
Journal: J Immunoassay Immunochem
PubMed ID: 37319429
Doi: 10.1080/15321819.2023.2224865
Products & Services: Molecular Biology Reagents   
SpyTag/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion
Authors: Vili Lampinen, Stina Gröhn, Saana Soppela, Vesna Blazevic, Vesa P Hytönen, Minna M Hankaniemi
Journal: Front Cell Infect Microbiol
PubMed ID: 37424789
Doi: 10.3389/fcimb.2023.1216364
Products & Services: Peptide Synthesis   
Structural insights into mechanisms of Argonaute protein-associated NADase activation in bacterial immunity
Authors: Xiaoshen Wang, Xuzichao Li, Guimei Yu, Lingling Zhang, Chendi Zhang, Yong Wang, Fumeng Liao, Yanan Wen, Hang Yin, Xiang Liu, Yong Wei, Zhuang Li, Zengqin Deng, Heng Zhang
Journal: Cell Res
PubMed ID: 37311833
Doi: 10.1038/s41422-023-00839-7
Plasmodium GPI-anchored micronemal antigen is essential for parasite transmission through the mosquito host
Authors: Charlie Jennison, Janna M Armstrong, Dorender A Dankwa, Nina Hertoghs, Sudhir Kumar, Biley A Abatiyow, Myo Naung, Nana K Minkah, Kristian E Swearingen, Robert Moritz, Alyssa E Barry, Stefan H I Kappe, Ashley M Vaughan
Journal: Mol Microbiol
PubMed ID: 37314965
Doi: 10.1111/mmi.15078
Products & Services: Molecular Biology Reagents   
SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice
Authors: Eun Kim, Muhammad S Khan , Alessandro Ferrari , Shaohua Huang , Josè C Sammartino, Elena Percivalle, Thomas W Kenniston, Irene Cassaniti , Fausto Baldanti, Andrea Gambotto
Journal: Microbiology Spectrum
PubMed ID: 37162333
Doi: PMC10269910
Products & Services: Codon Optimization   
Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
Authors: Nan Zhao, Jessica Sook Yuin Ho, Fanye Meng, Simin Zheng, Andrew P Kurland, Lu Tian, Martha Rea-Moreno, Xiangyang Song, Ji-Seon Seo, H Ümit Kaniskan, Aartjan J W Te Velthuis, Domenico Tortorella, Ya-Wen Chen, Jeffrey R Johnson, Jian Jin, Ivan Marazzi
Journal: Cell Host Microbe
PubMed ID: 37339625
Doi: 10.1016/j.chom.2023.05.030
Li-Mg-Si bioceramics provide a dynamic immuno-modulatory and repair-supportive microenvironment for peripheral nerve regeneration
Authors: Yiting Sun , Hongjian Zhang, Yu Zhang , Zheqi Liu , Dongming He , Wanlin Xu 4, Siyi Li , Chenping Zhang , Zhen Zhang
Journal: Bioact Mater.
PubMed ID: 37292230
Doi: 10.1016/j.bioactmat.2023.05.013
Efficient expression of a cytokine combination in Saccharomyces cerevisiae for cultured meat production
Authors: Qingzi Lei, Jun Ma, Guocheng Du, Jingwen Zhou, Xin Guan
Journal: Food Research International
Doi: 10.1016/j.foodres.2023.113017
Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe
Authors: Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim
Journal: Nucleic Acids Research
PubMed ID: 37144518
Doi: 10.1093/nar/gkad363
Products & Services: ORF cDNA Clones/MolecularCloud   
Characterization of the conserved features of the NSE6 subunit of the Physcomitrium patens SMC5/6 complex
Authors: Edit Lelkes , Jitka Jemelková , Marcela Holá , Barbora Štefanovie , Peter Kolesár , Radka Vágnerová , Eva Dvořák Tomaštíková , Ales Pecinka , Karel J Angelis , Jan J Paleček
Journal: Plant J .
PubMed ID: 37191775
Doi: 10.1111/tpj.16282
Products & Services: Gene Synthesis   
13C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme–Substrate Complex of an Active, N-Linked Glycosylated Lipoxygenase
Authors: Ajay Sharma , Chris Whittington , Mohammed Jabed , S Gage Hill , Anastasiia Kostenko , Tao Yu , Pengfei Li , Peter E Doan , Brian M Hoffman , Adam R Offenbacher
Journal: Biochemistry .
PubMed ID: 37115010
Doi: 10.1021/acs.biochem.3c00119
Products & Services: Gene Synthesis   
A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex
Authors: Hong-Wei Zhang, Kun Huang, Zhan-Xi Gu, Xiao-Xian Wu, Jia-Wei Wang, Yu Zhang
Journal: Nat Commun .
PubMed ID: 37253723
Doi: 10.1038/s41467-023-38619-x
Antibacterial mechanism of the novel antimicrobial peptide Jelleine-Ic and its efficacy in controlling Pseudomonas syringae pv actinidiae in kiwifruit
Authors: Mingyu Zhang, Lifang Wang, Wei Tang, Yue Xing, Pu Liu, Xiangli Dang
Journal: Pest Manag Sci
PubMed ID: 37184207
Doi: 10.1002/ps.7548
Products & Services: Molecular Biology Reagents   
Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction
Authors: Joka Pipercevic, Bastian Kohl, Ruta Gerasimaite, Véronique Comte-Miserez, Sarah Hostachy, Thomas Müntener, Elia Agustoni, Henning Jacob Jessen, Dorothea Fiedler, Andreas Mayer, Sebastian Hiller
Journal: Nat Commun
PubMed ID: 37156835
Doi: 10.1038/s41467-023-38315-w
Products & Services: Molecular Biology Reagents   
Small-Molecule-Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death
Authors: Rita A Avelar, Amy J Armstrong, Gracie Carvette, Riya Gupta, Noah Puleo, Jose A Colina, Peronne Joseph, Alexander M Sobeck, Caitlin M O'Connor, Brynne Raines, Agharnan Gandhi, Michele L Dziubinski, Daniel S Ma, Kimberly Resnick, Sareena Singh, Kristine Zanotti, Christa Nagel, Steven Waggoner, Daffyd G Thomas, Stephanie L Skala, Junran Zhang, Goutham Narla, Analisa DiFeo
Journal: Mol Cancer Ther
PubMed ID: 36788429
Doi: 10.1158/1535-7163.MCT-21-0880
Products & Services: CRISPR Plasmids   
Validation of immunoassays for the Chlamydia trachomatis antigen Pgp3 using a chimeric monoclonal antibody
Authors: Brook Goodhew, Xiaoling Tang, Jason Goldstein, Joo Lee, Diana Martin, Sarah Gwyn
Journal: Sci Rep
PubMed ID: 37142607
Doi: 10.1038/s41598-023-33834-4
In-cell kinetic stability is an essential trait in metallo-β-lactamase evolution
Authors: Lisandro J González, Guillermo Bahr, Mariano M González, Robert A Bonomo, Alejandro J Vila
Journal: Nat Chem Biol
PubMed ID: 37188957
Doi: 10.1038/s41589-023-01319-0
Products & Services: Gene Synthesis   
Electronegative clusters modulate folding status and RNA binding of unstructured RNA-binding proteins
Authors: Steve Zaharias, Talia Fargason, Rory Greer, Yuhua Song, Jun Zhang
Journal: Protein Sci
PubMed ID: 37060324
Doi: 10.1002/pro.4643
Products & Services: Gene Synthesis   
Deficient Immune Response following SARS-CoV-2 Vaccination in Patients with Hepatobiliary Carcinoma: A Forgotten, Vulnerable Group of Patients
Authors: Malte B Monin, Leona I Baier, Jens G Gorny, Moritz Berger, Taotao Zhou, Robert Mahn, Farsaneh Sadeghlar, Christian Möhring, Christoph Boesecke, Kathrin van Bremen, Jürgen K Rockstroh, Christian P Strassburg, Anna-Maria Eis-Hübinger, Matthias Schmid, Maria A Gonzalez-Carmona
Journal: Liver Cancer
PubMed ID: 37901199
Doi: 10.1159/000529608
Products & Services: Molecular Biology Reagents   
Development of new mutant alleles and markers for and via CRISPR/Cas9-mediated mutagenesis to reduce trypsin inhibitor content and activity in soybean seeds
Authors: Zhibo Wang, Zachary Shea, Luciana Rosso, Chao Shang, Jianyong Li, Patrick Bewick, Qi Li, Bingyu Zhao, Bo Zhang
Journal: Front Plant Sci
PubMed ID: 37223818
Doi: 10.3389/fpls.2023.1111680
Structural analysis of ING3 protein and histone H3 binding
Authors: Mariola Ferreras-Gutiérrez, Belén Chaves-Arquero, Amaia González-Magaña, Nekane Merino, Ignacio Amusategui-Mateu, Sonia Huecas, Francisco J Medrano, Francisco J Blanco
Journal: Int J Biol Macromol
PubMed ID: 37148949
Doi: 10.1016/j.ijbiomac.2023.124724
A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells
Authors: Peter J Cook, Su Jung Yang, Gene I Uenishi, Annaiz Grimm, Samuel E West, Li-Jie Wang, Chester Jacobs, Andrea Repele, Travis Drow, Ahmad Boukhris, Noelle P Dahl, Karen Sommer, Andrew M Scharenberg, David J Rawlings
Journal: Mol Ther
PubMed ID: 37147803
Doi: 10.1016/j.ymthe.2023.04.021
Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation
Authors: Jayde Lockyer, Andrew Reading, Silvia Vicenzi, Caroline Delandre, Owen Marshall, Robert Gasperini, Lisa Foa, John Y Lin
Journal: biorxiv
PubMed ID: 37214843
Doi: 10.1101/2023.05.06.539674
Leptospiral imelysin (LIC_10713) is secretory, immunogenic and binds to laminin, fibronectin, and collagen IV
Authors: Abhijit Sarma, Dhandapani Gunasekaran, Homen Phukan, Akhil Baby, Suneetha Hariharan, Arun Kumar De, Debasis Bhattacharya, Sankar Natesan, Jebasingh Tennyson, Madathiparambil Gopalakrishnan Madanan
Journal: Appl Microbiol Biotechnol
PubMed ID: 37227474
Doi: 10.1007/s00253-023-12573-6
Products & Services: Molecular Biology Reagents   
CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation
Authors: Min Qiu, Zhinang Yin, Honghong Wang, Lingyu Lei, Conghui Li, Yali Cui, Rong Dai, Peiyuan Yang, Ying Xiang, Qiuzi Li, Junhui Lv, Zhuang Hu, Min Chen, Hai-Bing Zhou, Pingping Fang, Ruijing Xiao, Kaiwei Liang
Journal: Sci Adv
PubMed ID: 37205756
Doi: 10.1126/sciadv.adf8698
Products & Services: Molecular Biology Reagents   
Analysis and comparisons of gene expression changes in patient- derived neurons from ROHHAD, CCHS, and PWS
Authors: A Kaitlyn Victor, Tayler Hedgecock, Martin Donaldson, Daniel Johnson, Casey M Rand, Debra E Weese-Mayer, Lawrence T Reiter
Journal: Front Pediatr
PubMed ID: 37234859
Doi: 10.3389/fped.2023.1090084
Products & Services: Molecular Biology Reagents   
Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa
Authors: Xingyun Wang, Cong Liu, Nino Rcheulishvili, Dimitri Papukashvili, Fengfei Xie, Jiao Zhao, Xing Hu, Kaiwei Yu, Nuo Yang, Xuehua Pan, Xueyan Liu, Peng George Wang, Yunjiao He
Journal: npj Vaccines
PubMed ID: 37231060
Doi: 10.1038/s41541-023-00672-4
Products & Services: Polyclonal Antibody Services   
Sel1-like proteins and peptides are the major -derived factors stimulating oxalate transport by human intestinal epithelial cells
Authors: Donna Arvans, Changsoo Chang, Altayeb Alshaikh, Christine Tesar, Gyorgy Babnigg, Don Wolfgeher, Stephen Kron, Dionysios Antonopoulos, Mohamed Bashir, Candace Cham, Mark Musch, Eugene Chang, Andrzej Joachimiak, Hatim Hassan
Journal: Am J Physiol Cell Physiol
PubMed ID: 37125773
Doi: 10.1152/ajpcell.00466.2021
Products & Services: Peptide Synthesis   
Complete integration of carbene-transfer chemistry into biosynthesis
Authors: Jing Huang, Andrew Quest, Pablo Cruz-Morales, Kai Deng, Jose Henrique Pereira, Devon Van Cura, Ramu Kakumanu, Edward E K Baidoo, Qingyun Dan, Yan Chen, Christopher J Petzold, Trent R Northen, Paul D Adams, Douglas S Clark, Emily P Balskus, John F Hartwig, Aindrila Mukhopadhyay, Jay D Keasling
Journal: Nature
PubMed ID: 37138074
Doi: 10.1038/s41586-023-06027-2
Products & Services: Recombinant Proteins   
De Novo Computational Design of a Lipase with Hydrolysis Activity towards Middle-Chained Fatty Acid Esters
Authors: Jinsha Huang, Xiaoman Xie, Zhen Zheng, Luona Ye, Pengbo Wang, Li Xu, Ying Wu, Jinyong Yan, Min Yang, Yunjun Yan
Journal: Int J Mol Sci
PubMed ID: 37239928
Doi: 10.3390/ijms24108581
Products & Services: Gene Synthesis   
Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis
Authors: Stephanie M Bozonet, Nicholas J Magon, Abigail J Schwartfeger, Andreas Konigstorfer, Sarah G Heath, Margreet C M Vissers, Vanessa K Morris, Christoph Göbl, James M Murphy, Guy S Salvesen, Mark B Hampton
Journal: J Biol Chem
PubMed ID: 37150321
Doi: 10.1016/j.jbc.2023.104792
Products & Services: Molecular Biology Reagents   
PTPMT1 protects cardiomyocytes from necroptosis induced by γ-ray irradiation through alleviating mitochondria injury
Authors: Jing Yi, Liang Yue, Yuning Zhang, Ning Tao, Han Duan, Lin Lv, Yingxia Tan, Hua Wang
Journal: Am J Physiol Cell Physiol
PubMed ID: 37154493
Doi: 10.1152/ajpcell.00466.2022
Products & Services: Codon Optimization   
Hsa_circ_0088036 promotes nonsmall cell lung cancer progression by regulating miR-1343-3p/Bcl-3 axis through TGFβ/Smad3/EMT signaling
Authors: Peng Ge, Xin Chen, Juan Liu, Ruijun Jing, Xingxing Zhang, Hanjie Li
Journal: Mol Carcinog
PubMed ID: 37132942
Doi: 10.1002/mc.23547
KLF2 inhibits colorectal cancer progression and metastasis by inducing ferroptosis via the PI3K/AKT signaling pathway
Authors: Jia Li, Ji Ling Jiang, Yi Mei Chen, Wei Qi Lu
Journal: J Pathol Clin Res
PubMed ID: 37147883
Doi: 10.1002/cjp2.325
Allosteric regulation of Senecavirus A 3Cpro proteolytic activity by an endogenous phospholipid
Authors: Hai-Fan Zhao, Liang Meng, Zhi Geng, Zeng-Qiang Gao, Yu-Hui Dong, Hai-Wei Wang, Heng Zhang
Journal: PLoS Pathog
PubMed ID: 37253057
Doi: 10.1371/journal.ppat.1011411
Products & Services: Molecular Biology Reagents   
Encapsulated Allografts Preclude Host Sensitization and Promote Ovarian Endocrine Function in Ovariectomized Young Rhesus Monkeys and Sensitized Mice
Authors: James R Day, Colleen L Flanagan, Anu David, Dennis J Hartigan-O'Connor, Mayara Garcia de Mattos Barbosa, Michele L Martinez, Charles Lee, Jenna Barnes, Evan Farkash, Mary Zelinski, Alice Tarantal, Marilia Cascalho, Ariella Shikanov
Journal: Bioengineering (Basel)
PubMed ID: 37237620
Doi: 10.3390/bioengineering10050550
Products & Services: Molecular Biology Reagents   
Phenotypic, Physiological, and Molecular Response of var under Different Light Quality Treatments Based on Leaf Color Changes
Authors: Yifan Zhang, Yang Liu, Lin Ling, Wenwen Huo, Yang Li, Lu Xu, Lili Xiang, Yujie Yang, Xingyao Xiong, Donglin Zhang, Xiaoying Yu, Yanlin Li
Journal: Plants (Basel)
PubMed ID: 37299148
Doi: 10.3390/plants12112169
Products & Services: Molecular Biology Reagents   
Purification of recombinant bacterial collagens containing structural perturbations
Authors: Sonal Gahlawat, Vikas Nanda, David I Shreiber
Journal: PLoS ONE
PubMed ID: 37196046
Doi: 10.1371/journal.pone.0285864
Products & Services: Plasmid DNA Preparation   
DPY30 Promotes Proliferation and Cell Cycle Progression of Colorectal Cancer Cells via Mediating H3K4 Trimethylation
Authors: Wei-Chao Su, Xiao-Mei Mao, Si-Yang Li, Chun-Ying Luo, Rui Fan, Hai-Feng Jiang, Lin-Jun Zhang, Ya-Tao Wang, Guo-Qiang Su, Dong-Yan Shen
Journal: Int J Med Sci
PubMed ID: 37324189
Doi: 10.7150/ijms.80073
Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV
Authors: Hiva Azizi, Jason P Knapp, Yue Li, Alice Berger, Marc-Alexandre Lafrance, Jannie Pedersen, Marc-Antoine de la Vega, Trina Racine, Chil-Yong Kang, Jamie F S Mann, Jimmy D Dikeakos, Gary Kobinger, Eric J Arts
Journal: Vaccines (Basel)
PubMed ID: 37243081
Doi: 10.3390/vaccines11050977
In silico design and validation of a novel multi-epitope vaccine candidate against structural proteins of Chikungunya virus using comprehensive immunoinformatics analyses
Authors: Shirin Mahmoodi, Javad Zamani Amirzakaria, Abdolmajid Ghasemian
Journal: PLoS ONE
PubMed ID: 37146081
Doi: 10.1371/journal.pone.0285177
Products & Services: Codon Optimization   
Profiling Enzyme Activity of l-Asparaginase II by NMR-Based Methyl Fingerprinting at Natural Abundance
Authors: Rachayita Nag, Srishti Joshi, Anurag Singh Rathore, Subhabrata Majumder
Journal: J Am Chem Soc
PubMed ID: 37154467
Doi: 10.1021/jacs.3c02154
Products & Services: DNA Sequencing   
Identification of a Novel Linear B-Cell Epitope of HbpA Protein from Using Monoclonal Antibody
Authors: Geyan Liu, Kang Wang, Zhen Yang, Xiaoyu Tang, Yung-Fu Chang, Ke Dai, Xinwei Tang, Bangdi Hu, Yiwen Zhang, Sanjie Cao, Xiaobo Huang, Qigui Yan, Rui Wu, Qin Zhao, Senyan Du, Xintian Wen, Yiping Wen
Journal: Int J Mol Sci
PubMed ID: 37239984
Doi: 10.3390/ijms24108638
Products & Services: Peptide Synthesis   
Immunogenicity and efficacy analyses of EPC002, ECA006, and EPCP009 protein subunit combinations as tuberculosis vaccine candidates
Authors: Ruihuan Wang, Xueting Fan, Yi Jiang, Guilian Li, Machao Li, Xiuqin Zhao, Xiuli Luan, Yunli Deng, Zixin Chen, Haican Liu, Kanglin Wan
Journal: Vaccine
PubMed ID: 37225573
Doi: 10.1016/j.vaccine.2023.04.003
Products & Services: Molecular Biology Reagents   
Development and characterization of a digital CRISPR/Cas13a based assay for rapid and sensitive diagnosis of severe fever with thrombocytopenia syndrome virus
Authors: Lulu Zuo , Jing Miao , Dongmei He , Zhixin Fang , Xin Zhang , Changyun Sun , Xiaoling Deng , Xiaolin Ma , Chao Yu , Gary Wong
Journal: Sensors and Actuators: B. Chemical
Doi: 10.1016/j.snb.2023.133789
Products & Services: DNA Sequencing   Custom DNA/RNA Oligos   
High light triggers flavonoid and polysaccharide synthesis through DoHY5-dependent signaling in Dendrobium officinale
Authors: Dongxiao Li, Guangying Ye, Jie Li, Zhenqin Lai, Siyou Ruan, Qi Qi, Zaihua Wang, Sujuan Duan, Hong-Lei Jin, Hong-Bin Wang
Journal: Plant J
PubMed ID: 37177908
Doi: 10.1111/tpj.16284
The global regulator SpoVG regulates Listeria monocytogenes biofilm formation
Authors: Changzheng Shi, Liping Zheng, Zhaoxin Lu, Xinyi Zhang, Xiaomei Bie
Journal: Microb Pathog
PubMed ID: 37148923
Doi: 10.1016/j.micpath.2023.106144
Divergent expression of aristaless1 and aristaless2 during embryonic appendage and pupal wing development in butterflies
Authors: Erick X Bayala, Isabella Cisneros, Darli Massardo, Nicholas W VanKuren, Marcus R Kronforst
Journal: BMC Biol
PubMed ID: 37170114
Doi: 10.1186/s12915-023-01602-5
Products & Services: Peptide Synthesis   
African Swine Fever Virus HLJ/18 CD2v Suppresses Type I IFN Production and IFN-Stimulated Genes Expression through Negatively Regulating cGMP-AMP Synthase-STING and IFN Signaling Pathways
Authors: Li Huang, Weiye Chen, Hongyang Liu, Mengdi Xue, Siqi Dong, Xiaohong Liu, Chunying Feng, Shinuo Cao, Guangqiang Ye, Qiongqiong Zhou, Zhaoxia Zhang, Jun Zheng, Jiangnan Li, Dongming Zhao, Zilong Wang, Encheng Sun, Hefeng Chen, Shuai Zhang, Xue Wang, Xianfeng Zhang, Xijun He, Yuntao Guan, Zhigao Bu, Changjiang Weng
Journal: J Immunol
PubMed ID: 36971697
Doi: 10.4049/jimmunol.2200813
Structural basis of NINJ1-mediated plasma membrane rupture in cell death
Authors: Morris Degen, José Carlos Santos, Kristyna Pluhackova, Gonzalo Cebrero, Saray Ramos, Gytis Jankevicius, Ella Hartenian, Undina Guillerm, Stefania A Mari, Bastian Kohl, Daniel J Müller, Paul Schanda, Timm Maier, Camilo Perez, Christian Sieben, Petr Broz, Sebastian Hiller
Journal: Nature
PubMed ID: 37198476
Doi: 10.1038/s41586-023-05991-z
Products & Services: Plasmid DNA Preparation   
SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype
Authors: Seung Bum Park, Mohsin Khan, Sai Chaitanya Chiliveri, Xin Hu, Parker Irvin, Madeleine Leek, Ailis Grieshaber, Zongyi Hu, Eun Sun Jang, Ad Bax, T Jake Liang
Journal: Commun Biol
PubMed ID: 37225764
Doi: 10.1038/s42003-023-04923-x
Products & Services: Gene Synthesis   
SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool
Authors: Yewei Ji, Yuan Luo, Yating Wu, Yao Sun, Lianfeng Zhao, Zhen Xue, Mengqi Sun, Xiaoqiong Wei, Zinan He, Shuangcheng Alivia Wu, Liangguang Leo Lin, You Lu, Lei Chang, Fei Chen, Siyu Chen, Wei Qian, Xiaoxi Xu, Shengnuo Chen, Dongli Pan, Zhangsen Zhou, Sheng Xia, Chih-Chi Andrew Hu, Tingbo Liang, Ling Qi
Journal: Nat Cell Biol
PubMed ID: 37142791
Doi: 10.1038/s41556-023-01138-4
Heterologous Expression of Plantaricin 423 and Mundticin ST4SA in Saccharomyces cerevisiae
Authors: Michelle Rossouw, Rosemary A Cripwell, Ross R Vermeulen, Anton D van Staden, Willem H van Zyl, Leon M T Dicks, Marinda Viljoen-Bloom
Journal: Probiotics Antimicrob Proteins
PubMed ID: 37171691
Doi: 10.1007/s12602-023-10082-6
Products & Services: Molecular Biology Reagents   
Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
Authors: Alexis González, Adriana Covarrubias-Pinto, Ramachandra M Bhaskara, Marius Glogger, Santosh K Kuncha, Audrey Xavier, Eric Seemann, Mohit Misra, Marina E Hoffmann, Bastian Bräuning, Ashwin Balakrishnan, Britta Qualmann, Volker Dötsch, Brenda A Schulman, Michael M Kessels, Christian A Hübner, Mike Heilemann, Gerhard Hummer, Ivan Dikić
Journal: Nature
PubMed ID: 37225996
Doi: 10.1038/s41586-023-06089-2
Structural Characterization of the Staphylococcus aureus Targeting Lectin Peptides from Garlic (Allium sativum L) by Liquid Nitrogen Grinding Coupled with the Proteomic and Antimicrobial Mechanism Analysis
Authors: Shuqin Li, Nannan Li, Yajie Wang, Xiaoyu Zhang, Jia Wang, Min Zhang, Haixia Chen
Journal: Probiotics Antimicrob Proteins
PubMed ID: 37217612
Doi: 10.1007/s12602-023-10078-2
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours
Authors: Xiaohong Chen, Shuang Wang, Yuxuan Chen, Huhu Xin, Shuaishuai Zhang, Di Wu, Yanan Xue, Menglei Zha, Hongjun Li, Kai Li, Zhen Gu, Wei Wei, Yuan Ping
Journal: NATURE NANOTECHNOLOGY
PubMed ID: 37188968
Doi: 10.1038/s41565-023-01378-3
Products & Services: Recombinant Proteins   
Refining the genomic determinants underlying escape from X-chromosome inactivation
Authors: Samantha Peeters, Tiffany Leung, Oriol Fornes, Rachelle A Farkas, Wyeth W Wasserman, Carolyn J Brown
Journal: NAR genomic and bioimformatics
PubMed ID: 37260510
Doi: 10.1093/nargab/lqad052
Products & Services: Gene Synthesis   
The Adjuvant Combination of dmLT and Monophosphoryl Lipid A Activates the Canonical, Nonpyroptotic NLRP3 Inflammasome in Dendritic Cells and Significantly Interacts to Expand Antigen-Specific CD4 T Cells
Authors: David L Bauer, Louay Bachnak, Vanessa M Limbert, Rebecca M Horowitz, Robin L Baudier, Shaina J D'Souza, Victoria E Immethun, Jonathan R Kurtz, Samuel B Grant, James B McLachlan
Journal: J Immunol
PubMed ID: 37023458
Doi: 10.4049/jimmunol.2200221
Products & Services: Peptide Synthesis   
Eight-Month Follow-up After the Third Dose of BNT162b2 Vaccine in Healthcare Workers: The Question of a Fourth Dose
Authors: Sung Hee Lim, Seong Hyeok Choi, Ji Youn Kim, Bora Kim, Han Jo Kim, Se Hyung Kim, Chan Kyu Kim, Seong Kyu Park, Jina Yun
Journal: J Korean Med Sci
PubMed ID: 37158775
Doi: 10.3346/jkms.2023.38.e139
m6A-enriched lncRNA LINC00839 promotes tumor progression by enhancing TAF15-mediated transcription of amine oxidase AOC1 in nasopharyngeal carcinoma
Authors: Wei-Hong Zheng, Zhi-Qing Long, Zi-Qi Zheng, Lu-Lu Zhang, Ye-Lin Liang, Zhi-Xuan Li, Jia-Wei Lv, Jia Kou, Xiao-Hong Hong, Shi-Wei He, Rui Xu, Guan-Qun Zhou, Na Liu, Jun Ma, Ying Sun, Li Lin, Denghui Wei
Journal: J Biol Chem
PubMed ID: 37257820
Doi: 10.1016/j.jbc.2023.104873
Adenoviral-vectored epigraph vaccine elicits robust, durable, and protective immunity against H3 influenza A virus in swine
Authors: Erika Petro-Turnquist, Matthew Pekarek, Nicholas Jeanjaquet, Cedric Wooledge, David Steffen, Hiep Vu, Eric A Weaver
Journal: Front Immunol
PubMed ID: 37256131
Doi: 10.3389/fimmu.2023.1143451
Products & Services: Peptide Synthesis   
Immunological comparison of recombinant shrimp allergen Pen m 4, produced in Pichia pastoris and Escherichia coli
Authors: Juta Rainyte, Gintautas Zvirblis, Mindaugas Zaveckas, Indre Kucinskaite-Kodze, Laimis Silimavicius, Rasa Petraityte-Burneikiene
Journal: J Biotechnol
PubMed ID: 37164269
Doi: 10.1016/j.jbiotec.2023.05.002
Products & Services: Molecular Biology Reagents   
Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies
Authors: Wei Shi, Yin Wang, Yuehui Zhao, Justin Jimin Kim, Haoyan Li, Chenling Meng, Feiyu Chen, Jie Zhang, Duncan H Mak, Vivien Van, Javier Leo, Brad St Croix, Ana Aparicio, Di Zhao
Journal: Sci Transl Med
PubMed ID: 37163614
Doi: 10.1126/scitranslmed.adf6724
Products & Services: Molecular Biology Reagents   
Henipavirus Matrix Protein Employs a Non-Classical Nuclear Localization Signal Binding Mechanism
Authors: Camilla M Donnelly, Olivia A Vogel, Megan R Edwards, Paige E Taylor, Justin A Roby, Jade K Forwood, Christopher F Basler
Journal: Viruses
PubMed ID: 37376602
Doi: 10.3390/v15061302
Products & Services: Catalog Peptides   
Adaptive evolution to the natural and anthropogenic environment in a global invasive crop pest, the cotton bollworm
Authors: Minghui Jin, Henry L. North, Yan Peng, Hangwei Liu,, Bo Liu,, Ruiqing Pan, Yan Zhou, Weigang Zheng, Kaiyu Liu, Bo Yang, Lei Zhang, Qi Xu, Samia Elfekih,Wendy A. Valencia-Montoya, Tom Walsh, Peng Cui, Yongfeng Zhou, Kenneth Wilson, Chris Jiggins,Kongming Wu,and Yutao Xiao,
Journal: The Innovation
Doi: 10.1016/j.xinn.2023.100454
Products & Services: Gene Synthesis   
Safety and Efficacy of Intravenous and Intrathecal Delivery of AAV9-Mediated ARSA in Minipigs
Authors: Aysilu Mullagulova , Alisa Shaimardanova , Valeriya Solovyeva , Yana Mukhamedshina , Daria Chulpanova , Alexander Kostennikov, Shaza Issa, Albert Rizvanov
Journal: Int J Mol Sci .
PubMed ID: 37298156
Doi: 10.3390/ijms24119204
Products & Services: Gene Synthesis   
Site-specific gene knock-in and bacterial phytase gene expression in Cas9 RNP-mediated HDR
Authors: Hassan Zadabbas Shahabadi, Arash Akbarzadeh, Hamideh Ofoghi, Saeid Kadkhodaei
Journal: Front Plant Sci
PubMed ID: 37275253
Doi: 10.3389/fpls.2023.1150436
An Aurora B-RPA signaling axis secures chromosome segregation fidelity
Authors: Poonam Roshan, Sahiti Kuppa, Jenna R Mattice, Vikas Kaushik, Rahul Chadda, Nilisha Pokhrel, Brunda R Tumala, Aparna Biswas, Brian Bothner, Edwin Antony, Sofia Origanti
Journal: Nat Commun
PubMed ID: 37230964
Doi: 10.1038/s41467-023-38711-2
Products & Services: Codon Optimization   
Chronic intermittent hypobaric hypoxia ameliorates osteoporosis after spinal cord injury through balancing osteoblast and osteoclast activities in rats
Authors: Li Zhang, Yingchao Yin, Jialiang Guo, Lin Jin, Zhiyong Hou
Journal: Front Endocrinol (Lausanne)
PubMed ID: 37229453
Doi: 10.3389/fendo.2023.1035186
Products & Services: PCR Cloning and Subcloning   
Hemophore-like proteins produced by periodontopathogens are recognized by the host immune system and react differentially with IgG antibodies
Authors: Michał Śmiga, Klaudia Siemińska, Soraya C Trindade, Isaac S Gomes-Filho, Ellen K Nobre Dos Santos, Teresa Olczak
Journal: J Oral Microbiol
PubMed ID: 37213663
Doi: 10.1080/20002297.2023.2214455
Products & Services: Peptide Synthesis   
Rapid Quantitation of Various Therapeutic Monoclonal Antibodies Using Membranes with Fc-Specific Ligands
Authors: Junyan Yang, Raluca Ostafe, Christopher J Welch, Brandy Verhalen, Ivan L Budyak, Merlin L Bruening
Journal: Anal Chem
PubMed ID: 37216615
Doi: 10.1021/acs.analchem.3c00531
Products & Services: Peptide Synthesis   
Hijacking of Host Plasminogen by () via GAPDH: an Important Virulence Mechanism To Promote Adhesion and Extracellular Matrix Degradation
Authors: Jiying Wang, Shiyang Li, Junhong Chen, Lanxi Gan, Jia Wang, Qiyan Xiong, Zhixin Feng, Quan Li, Zhibang Deng, Xiaomin Yuan, Yanfei Yu
Journal: Microbiol Spectr
PubMed ID: 37199643
Doi: 10.1128/spectrum.00218-23
Products & Services: Molecular Biology Reagents   
Ionic displacement of Ca by Pb in calmodulin is affected by arrhythmia-associated mutations
Authors: Valerio Marino, Giuditta Dal Cortivo, Daniele Dell'Orco
Journal: Biochim Biophys Acta Mol Cell Res
PubMed ID: 37201768
Doi: 10.1016/j.bbamcr.2023.119490
Products & Services: Codon Optimization   
KREH1 RNA helicase activity promotes utilization of initiator gRNAs across multiple mRNAs in trypanosome RNA editing
Authors: Ashutosh P Dubey, Brianna L Tylec, Amartya Mishra, Katherine Sortino, Runpu Chen, Yijun Sun, Laurie K Read
Journal: Nucleic Acids Research
PubMed ID: 37140035
Doi: doi.org/10.1093/nar/gkad292
Products & Services: Gene Synthesis   
Mechanism of assembly, activation and lysine selection by the SIN3B histone deacetylase complex
Authors: Mandy S M Wan, Reyhan Muhammad, Marios G Koliopoulos, Theodoros I Roumeliotis, Jyoti S Choudhary, Claudio Alfieri
Journal: nature communications
PubMed ID: 37137925
Doi: 10.1038/s41467-023-38276-0
Products & Services: Gene Synthesis   
Ligand and G-protein selectivity in the κ-opioid receptor
Authors: Jianming Han, Jingying Zhang, Antonina L Nazarova, Sarah M Bernhard, Brian E Krumm, Lei Zhao, Jordy Homing Lam, Vipin A Rangari, Susruta Majumdar, David E Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F Fay, Tao Che
Journal: Nature
PubMed ID: 37138078
Doi: 10.1038/s41586-023-06030-7
Diversity and Genetic Reassortment of Keystone Virus in Mosquito Populations in Florida
Authors: Maha A Elbadry, Caroline A Efstathion, Whitney A Qualls, Massimiliano S Tagliamonte, Md Mahbubul Alam, Md Siddiqur Rahman Khan, Sadie J Ryan, Rui-de Xue, Remi N Charrel, Lea Bangonan, Marco Salemi, Nazli Ayhan, John A Lednicky, J Glenn Morris
Journal: Am J Trop Med Hyg
PubMed ID: 37127267
Doi: 10.4269/ajtmh.22-0594
Bioluminescence resonance energy transfer biosensor for measuring activity of a protease secreted by Pseudomonas fluorescens growing in milk
Authors: H Dacres, F Weihs, J Wang, A Anderson, S C Trowell
Journal: Anal Chim Acta
PubMed ID: 37311608
Doi: 10.1016/j.aca.2023.341401
Photobiomodulation therapy at 632 nm wavelength ameliorates intrauterine adhesion via activation of cAMP/PKA/CREB pathway
Authors: Hongjie Zheng, Caixia Wang, Shan Wu, Qing Pei, Min Yao
Journal: Photochem Photobiol
PubMed ID: 37212452
Doi: 10.1111/php.13813
Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
Authors: Damon A Hofman, Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R Clauser, Alexandra L Condurat, Jip T van Dinter, Sem A G Engels, Amy Goodale, Jasper van der Lugt, Tanaz Abid, Li Wang, Kevin N Zhou, Jayne Vogelzang, Keith L Ligon, Timothy N Phoenix, Jennifer A Roth, David E Root, Norbert Hubner, Todd R Golub, Pratiti Bandopadhayay, Sebastiaan van Heesch, John R Prensner
Journal: biorxiv
PubMed ID: 37205492
Doi: 10.1101/2023.05.04.539399

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