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A Single Vaccination of Chimeric Bivalent Virus-Like Particle Vaccine Confers Protection Against H9N2 and H3N2 Avian Influenza in Commercial Broilers and Allows a Strategy of Differentiating Infected from Vaccinated Animals
Authors: Yi-Xue Sun, Zheng-Rong Li, Peng-Ju Zhang, Jin-Hong Han, Hai-Yang Di, Jia-Yi Qin, Yan-Long Cong
Journal: Front Immunol
PubMed ID: 35874682
Doi: 10.3389/fimmu.2022.902515
Products & Services: Gene Synthesis   
Engineering a tunable bicistronic TetR autoregulation expression system in
Authors: Monica Bertucci, Ky Ariano, Meg Zumsteg, Paul Schweiger
Journal: PeerJ
PubMed ID: 35873911
Doi: 10.7717/peerj.13639
Products & Services: PCR Cloning and Subcloning   
Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus
Authors: Francesco Aulicino, Martin Pelosse, Christine Toelzer, Julien Capin, Erwin Ilegems, Parisa Meysami, Ruth Rollarson, Per-Olof Berggren, Mark Simon Dillingham, Christiane Schaffitzel, Moin A Saleem, Gavin I Welsh, Imre Berger
Journal: Nucleic Acids Res
PubMed ID: 35801912
Doi: 10.1093/nar/gkac587
Products & Services: Synthetic sgRNA and crRNA Service   
Durability of the Neutralizing Antibody Response to mRNA Booster Vaccination Against SARS-CoV-2 BA2121 and BA4/5 Variants
Authors: Panke Qu, Julia N Faraone, John P Evans, Yi-Min Zheng, Claire Carlin, Gerard Lozanski, Linda J Saif, Eugene M Oltz, Richard J Gumina, Shan-Lu Liu
Journal: biorxiv
PubMed ID: 35898337
Doi: 10.1101/2022.07.21.501010
Products & Services: Plasmid DNA Preparation   
Impact of the temperature on the interactions between common variants of the SARS-CoV-2 receptor binding domain and the human ACE2
Authors: Catherine Forest-Nault, Izel Koyuturk, Jimmy Gaudreault, Alex Pelletier, Denis L'Abbé, Brian Cass, Louis Bisson, Alina Burlacu, Laurence Delafosse, Matthew Stuible, Olivier Henry, Gregory De Crescenzo, Yves Durocher
Journal: Sci Rep
PubMed ID: 35798770
Doi: 10.1038/s41598-022-15215-5
Products & Services: Mammalian Expression   
Limited Correlation between SARS-CoV-2 Serologic Assays for Identification of High-Titer COVID-19 Convalescent Plasma Using FDA Thresholds
Authors: Nicholas E Larkey, Radwa Ewaisha, Michael A Lasho, Matthew M Roforth, Dane Granger, Calvin R Jerde, Liang Wu, Amy Gorsh, Stephen A Klassen, Jonathon W Senefeld, Michael J Joyner, Nikola A Baumann, Elitza S Theel, John R Mills
Journal: Microbiol Spectr
PubMed ID: 35862939
Doi: 10.1128/spectrum.01154-22
Pro-Survival Factor EDEM3 Confers Therapy Resistance in Prostate Cancer
Authors: Emma Scott, Rebecca Garnham, Kathleen Cheung, Adam Duxfield, David J Elliott, Jennifer Munkley
Journal: Int J Mol Sci
PubMed ID: 35897761
Doi: 10.3390/ijms23158184
Products & Services: Custom Vector Construction   
An adaptable platform for in-house hepatitis C serology
Authors: Jannie Pedersen, Irène Pegha Moukandja, Stella Ndidi, Anna-Louise Sørensen, Ismaël Hervé Koumakpayi, Jean-Bernard Lekana-Douki, Marie-Louise Vachon, Nina Weis, Gary Kobinger, Hugues Fausther-Bovendo
Journal: J Virol Methods
PubMed ID: 35850366
Doi: 10.1016/j.jviromet.2022.114586
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Physical activity and antibody persistence 6 months after the second dose of CoronaVac in immunocompromised patients
Authors: Bruno Gualano, Ítalo Ribeiro Lemes, Rafael Pires da Silva, Ana Jéssica Pinto, Bruna Caruso Mazzolani, Fabiana Infante Smaira, Sofia Mendes Sieczkowska, Nádia Emi Aikawa, Sandra Pasoto, Ana Cristina Medeiros-Ribeiro, Carla Saad, Emily Yuk, Clovis Silva, Paul Swinton, Pedro Curi Hallal, Hamilton Roschel, Eloisa Bonfa
Journal: Scand J Med Sci Sports
PubMed ID: 35844042
Doi: 10.1111/sms.14213
High Mobility Group Protein B1 Decreases Surface Localization of PD-1 to Augment T-cell Activation
Authors: Qun Gao, Shumin Wang, Feng Li, Jingyao Lian, Shaoyan Cheng, Dongli Yue, Zhen Zhang, Shasha Liu, Feifei Ren, Daiqun Zhang, Shengdian Wang, Liping Wang, Yi Zhang
Journal: Cancer Immunol Res
PubMed ID: 35580259
Doi: 10.1158/2326-6066.CIR-21-0652
Products & Services: Recombinant Proteins   
Structures of the T cell potassium channel Kv13 with immunoglobulin modulators
Authors: Purushotham Selvakumar, Ana I Fernández-Mariño, Nandish Khanra, Changhao He, Alice J Paquette, Bing Wang, Ruiqi Huang, Vaughn V Smider, William J Rice, Kenton J Swartz, Joel R Meyerson
Journal: Nat Commun
PubMed ID: 35788586
Doi: 10.1038/s41467-022-31285-5
Products & Services: Plasmid DNA Preparation   
Kalium channelrhodopsins are natural light-gated potassium channels that mediate optogenetic inhibition
Authors: Elena G Govorunova , Yueyang Gou , Oleg A Sineshchekov , Hai Li , Xiaoyu Lu , Yumei Wang , Leonid S Brown , François St-Pierre , Mingshan Xue , John L Spudich
Journal: Nature neuroscience
PubMed ID: 35726059
Doi: 10.1038/s41593-022-01094-6
Products & Services: Gene Synthesis   
Core cysteine residues in the Plasminogen-Apple-Nematode (PAN) domain are critical for HGF/c-MET signaling
Authors: Debjani Pal , Kuntal De , Carly M Shanks , Kai Feng , Timothy B Yates , Jennifer Morrell-Falvey , Russell B Davidson , Jerry M Parks , Wellington Muchero
Journal: Commun Biol
PubMed ID: 35778602
Doi: 10.1038/s42003-022-03582-8
Hsp70 inhibits the replication of Fowl Adenovirous serotype 4 by suppressing viral Hexon with the assistance of DnaJC7
Authors: Jie Cao , Shuhui Liu , Meng Liu , Shuaiwen Wang , Zhenwei Bi , Wentao Fan , Zhiyu Shi , Suquan Song , Liping Yan
Journal: J Virol
PubMed ID: 35852354
Doi: 10.1128/jvi.00807-22
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker
Authors: Aslan Mansurov , Peyman Hosseinchi, Kevin Chang, Abigail L Lauterbach, Laura T Gray , Aaron T Alpar , Erica Budina , Anna J Slezak , Seounghun Kang, Shijie Cao, Ani Solanki , Suzana Gomes , John-Michael Williford, Melody A Swartz , Juan L Mendoza , Jun Ishihara , Jeffrey A Hubbell
Journal: Nat Biomed Eng
PubMed ID: 35534574
Doi: 10.1038/s41551-022-00888-0
Products & Services: Mammalian Expression   
Identification of nucleoside monophosphates and their epigenetic modifications using an engineered nanopore.
Authors: Yuqin Wang , Shanyu Zhang , Wendong Jia ,Pingping Fan , Liying Wang , Xinyue Li , Jialu Chen , Zhenyuan Cao , Xiaoyu Du , Yao Liu , Kefan Wang , Chengzhen Hu , Jinyue Zhang , Jun Hu , Panke Zhang , Hong-Yuan Chen , Shuo Huang
Journal: Nat Nanotechnol
PubMed ID: 35851382
Doi: 10.1038/s41565-022-01169-2
Products & Services: Gene Synthesis   
Oncolytic adenovirus with MUC16-BiTE shows enhanced antitumor immune response by reversing the tumor microenvironment in PDX model of ovarian cancer
Authors: Qiuman Wang , Xinyue Ma , Huan Wu , Chen Zhao 1, Jingying Chen , Rongrong Li , Shi Yan , Yingwei Li , Qing Zhang , Kun Song , Cunzhong Yuan , Beihua Kong
Journal: Oncoimmunology
PubMed ID: 35800156
Doi: 10.1080/2162402X.2022.2096362 Free PMC article
Developing and validating SARS-CoV-2 assays for nonhuman primate surveillance
Authors: JoAnn Yee, Amanda Carpenter, Peter Nham, Bryson Halley, Koen K A Van Rompay, Jeffrey Roberts
Journal: J Med Primatol
PubMed ID: 35794847
Doi: 10.1111/jmp.12604
Products & Services: Mammalian Expression   
CaMKII Inhibition Attenuates Distinct Gain-of-Function Effects Produced by Mutant Nav16 Channels and Reduces Neuronal Excitability
Authors: Agnes S Zybura, Firoj K Sahoo, Andy Hudmon, Theodore R Cummins
Journal: Cells
PubMed ID: 35805192
Doi: 10.3390/cells11132108
Products & Services: Mammalian Expression   
Efficient multiplex CRISPR/Cpf1 (Cas12a) genome editing system in Aspergillus aculeatus TBRC 277
Authors: Dede Abdulrachman, Verawat Champreda, Lily Eurwilaichitr, Duriya Chantasingh, Kusol Pootanakit
Journal: J Biotechnol
PubMed ID: 35788357
Doi: 10.1016/j.jbiotec.2022.06.011
Products & Services: Synthetic sgRNA and crRNA Service   
Ancestrally Reconstructed von Willebrand Factor Reveals Evidence for Trench Warfare Coevolution between Opossums and Pit Vipers
Authors: Danielle H Drabeck, Alexandra Rucavado, Erika Hingst-Zaher, Antony Dean, Sharon A Jansa
Journal: Mol Biol Evol
PubMed ID: 35723968
Doi: 10.1093/molbev/msac140
Products & Services: Gene Synthesis   
Calcium responses to external mechanical stimuli in the multicellular stage of Dictyostelium discoideum
Authors: Hidenori Hashimura, Yusuke V Morimoto, Yusei Hirayama, Masahiro Ueda
Journal: Sci Rep
PubMed ID: 35859163
Doi: 10.1038/s41598-022-16774-3
Products & Services: GenParts™ DNA Fragments   
miR-301b-5p and its target gene nfatc2ip regulate inflammatory responses in the liver of rainbow trout (Oncorhynchus mykiss) under high temperature stress
Authors: Tianqing Huang, Wei Gu, Enhui Liu, Bingqian Wang, Gaochao Wang, Fulin Dong, Fuyuan Guo, Wenlong Jiao, Yanchun Sun, Xiance Wang, Shanwei Li, Gefeng Xu
Journal: Ecotoxicol Environ Saf
PubMed ID: 35901591
Doi: 10.1016/j.ecoenv.2022.113915
Products & Services: Plasmid DNA Preparation   
An immunodetection assay developed using cobra cytotoxin-specific antibodies: Potential diagnostics for cobra envenoming
Authors: Hui Ling Ong, Choo Hock Tan, Louisa Pernee Lee, Sook Mei Khor, Kae Yi Tan
Journal: Toxicon
PubMed ID: 35868411
Doi: 10.1016/j.toxicon.2022.07.010
Products & Services: Catalog Antibody   
A Single Dose of Anti-HBsAg Antibody-Encoding mRNA-LNPs Suppressed HBsAg Expression: a Potential Cure of Chronic Hepatitis B Virus Infection
Authors: Binfan Chen, Yuchen Chen, Jian Li, Chunyu Wang, Wenping Song, Yumei Wen, Jinzhong Lin, Yanling Wu, Tianlei Ying
Journal: MBio
PubMed ID: 35862767
Doi: 10.1128/mbio.01612-22
Products & Services: Catalog Antibody   
Phage defence by deaminase-mediated depletion of deoxynucleotides in bacteria
Authors: Brian Y Hsueh, Geoffrey B Severin, Clinton A Elg, Evan J Waldron, Abhiruchi Kant, Alex J Wessel, John A Dover, Christopher R Rhoades, Benjamin J Ridenhour, Kristin N Parent, Matthew B Neiditch, Janani Ravi, Eva M Top, Christopher M Waters
Journal: Nat Microbiol
PubMed ID: 35817890
Doi: 10.1038/s41564-022-01162-4
Products & Services: Catalog Antibody   
Sequence grammar underlying the unfolding and phase separation of globular proteins
Authors: Kiersten M Ruff, Yoon Hee Choi, Dezerae Cox, Angelique R Ormsby, Yoochan Myung, David B Ascher, Sheena E Radford, Rohit V Pappu, Danny M Hatters
Journal: Mol Cell
PubMed ID: 35853451
Doi: 10.1016/j.molcel.2022.06.024
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Screening circular RNAs with functional potential using the RfxCas13d/BSJ-gRNA system
Authors: Siqi Li, Hao Wu, Ling-Ling Chen
Journal: Nat Protoc
PubMed ID: 35831613
Doi: 10.1038/s41596-022-00715-5
Products & Services: Custom DNA/RNA Oligos   
SARS-CoV-2 Epitopes following Infection and Vaccination Overlap Known Neutralizing Antibody Sites
Authors: Li Yang, Te Liang, Lane M Pierson, Hongye Wang, Jesse K Fletcher, Shu Wang, Duran Bao, Lili Zhang, Zhen Huang, Wenshu Zheng, Xiaomei Zhang, Heewon Park, Yuwen Li, James E Robinson, Amy K Feehan, Christopher J Lyon, Jing Cao, Lisa A Morici, Chenzhong Li, Chad J Roy, Xiaobo Yu, Tony Hu
Journal: Research (Wash D C)
PubMed ID: 35928300
Doi: 10.34133/2022/9769803
Products & Services: Catalog Peptides   
Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut
Authors: Víctor Taleb, Qinghua Liao, Yoshiki Narimatsu, Ana García-García, Ismael Compañón, Rafael Junqueira Borges, Andrés Manuel González-Ramírez, Francisco Corzana, Henrik Clausen, Carme Rovira, Ramon Hurtado-Guerrero
Journal: Nat Commun
PubMed ID: 35882872
Doi: 10.1038/s41467-022-32021-9
Products & Services: Mutagenesis Services   
Phage Particles of Controlled Length and Genome for Targeted Glioblastoma Imaging and Therapeutic Delivery
Authors: Uyanga Tsedev, Ching-Wei Lin, Gaelen T Hess, Jann N Sarkaria, Fred C Lam, Angela M Belcher
Journal: ACS Nano
PubMed ID: 35830573
Doi: 10.1021/acsnano.1c08720
Products & Services: Plasmid DNA Preparation   
The Unfolded-Protein Response Triggers the Arthropod Immune Deficiency Pathway
Authors: Lindsay C Sidak-Loftis, Kristin L Rosche, Natasha Pence, Jessica K Ujczo, Joanna Hurtado, Elis A Fisk, Alan G Goodman, Susan M Noh, John W Peters, Dana K Shaw
Journal: MBio
PubMed ID: 35862781
Doi: 10.1128/mbio.00703-22
Products & Services: Mammalian Expression   
Conformational landscape of the yeast SAGA complex as revealed by cryo-EM
Authors: Diana Vasyliuk, Joeseph Felt, Ellen D Zhong, Bonnie Berger, Joseph H Davis, Calvin K Yip
Journal: Sci Rep
PubMed ID: 35853968
Doi: 10.1038/s41598-022-16391-0
Protective effects of small heat shock proteins in Daphnia magna against heavy metal exposure
Authors: Muyi Li, Ting Tang, Fengyu Yuan, Yuming Zhang, Fengchao Li, Fengsong Liu
Journal: Sci Total Environ
PubMed ID: 35907523
Doi: 10.1016/j.scitotenv.2022.157565
Development and applications of a TaqMan based quantitative real-time PCR for the rapid detection of Pigeon circovirus (PiCV)
Authors: Babu K Nath, Shubhagata Das, Tridip Das, Jade K Forwood, Shane R Raidal
Journal: J Virol Methods
PubMed ID: 35870671
Doi: 10.1016/j.jviromet.2022.114588
Cholesterol Deprivation Drives DHEA Biosynthesis in Human Adrenals
Authors: Emanuele Pignatti, Emre Murat Altinkilic, Konstantin Bräutigam, Michael Grössl, Aurel Perren, Mihaela Zavolan, Christa E Flück
Journal: Endocrinology
PubMed ID: 35583599
Doi: 10.1210/endocr/bqac076
Products & Services: Plasmid DNA Preparation   
An Engineered λ Phage Enables Enhanced and Strain-Specific Killing of Enterohemorrhagic Escherichia coli
Authors: Menglu Jin, Jingchao Chen, Xueyang Zhao, Guoru Hu, Hailei Wang, Zhi Liu, Wei-Hua Chen
Journal: Microbiol Spectr
PubMed ID: 35876591
Doi: 10.1128/spectrum.01271-22
Products & Services: Gene Synthesis   
Development and Assessment of Herpes Simplex Virus Type 1 (HSV-1) Amplicon Vectors with Sensory Neuron-Selective Promoters
Authors: Charles Joussain, Olivier Le Coz, Andrey Pichugin, Peggy Marconi, Filip Lim, Mariaconcetta Sicurella, Keith Foster, François Giuliano, Alberto L Epstein, Alejandro Aranda Muñoz
Journal: Int J Mol Sci
PubMed ID: 35955608
Doi: 10.3390/ijms23158474
Products & Services: Gene Synthesis   
Impacts of a Zwitterionic Peptide on its Fusion Protein
Authors: Patrick McMullen, Liang Fang, Qi Qiao, Qing Shao, Shaoyi Jiang
Journal: Bioconjug Chem
PubMed ID: 35852436
Doi: 10.1021/acs.bioconjchem.2c00176
Products & Services: Custom DNA/RNA Oligos   
Paraneoplastic Pemphigus Autoantibodies Against C-terminus of Desmoplakin Induced Acantholysis and
Authors: Xue Wang, Rui Wang, Dingfang Bu, Leyi Wang, Yuexin Zhang, Yuan Chang, Chenyang Zhang, Xixue Chen, Xuejun Zhu, Zhi Liu, Mingyue Wang
Journal: Front Immunol
PubMed ID: 35911677
Doi: 10.3389/fimmu.2022.886226
Products & Services: Bacterial Expression   
In silico identification of two peptides with antibacterial activity against multidrug-resistant Staphylococcus aureus
Authors: Linda B Oyama, Hamza Olleik, Ana Carolina Nery Teixeira, Matheus M Guidini, James A Pickup, Brandon Yeo Pei Hui, Nicolas Vidal, Alan R Cookson, Hannah Vallin, Toby Wilkinson, Denise M S Bazzolli, Jennifer Richards, Mandy Wootton, Ralf Mikut, Kai Hilpert, Marc Maresca, Josette Perrier, Matthias Hess, Hilario C Mantovani, Narcis Fernandez-Fuentes, Christopher J Creevey, Sharon A Huws
Journal: NPJ Biofilms Microbiomes
PubMed ID: 35835775
Doi: 10.1038/s41522-022-00320-0
Rhesus rotavirus receptor-binding site affects high mobility group box 1 release, altering the pathogenesis of experimental biliary atresia
Authors: Sujit K Mohanty, Bryan Donnelly, Haley Temple, Sarah Mowery, Holly M Poling, Jaroslaw Meller, Astha Malik, Monica McNeal, Greg Tiao
Journal: Hepatol Commun
PubMed ID: 35866580
Doi: 10.1002/hep4.2024
Products & Services: Catalog Peptides   
The transient expression of recombinant proteins in plant cell packs facilitates stable isotope labelling for NMR spectroscopy
Authors: Patrick Opdensteinen, Laura E Sperl, Mariam Mohamadi, Nicole Kündgen-Redding, Franz Hagn, Johannes Felix Buyel
Journal: Plant Biotechnol J
PubMed ID: 35702941
Doi: 10.1111/pbi.13873
The role of hepatic Surf4 in lipoprotein metabolism and the development of atherosclerosis in apoE mice
Authors: Yishi Shen, Hong-Mei Gu, Lei Zhai, Binxiang Wang, Shucun Qin, Da-Wei Zhang
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
PubMed ID: 35803528
Doi: 10.1016/j.bbalip.2022.159196
Products & Services: Catalog Peptides   
Antitumor efficacy of MUC1-derived variable epitope library treatments in a mouse model of breast cancer
Authors: Josué Odales, Rodolfo Servín-Blanco, Fernando Martínez-Cortés, Jesus Guzman Valle, Allan Noé Domínguez-Romero, Goar Gevorkian, Karen Manoutcharian
Journal: Vaccine
PubMed ID: 35788294
Doi: 10.1016/j.vaccine.2022.06.062
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O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1
Authors: Qiang Zhu, Hong Zhou, Liming Wu, Zhenyuan Lai, Didi Geng, Weiwei Yang, Jie Zhang, Zhiya Fan, Weijie Qin, Yong Wang, Ruhong Zhou, Wen Yi
Journal: Nat Chem Biol
PubMed ID: 35879546
Doi: 10.1038/s41589-022-01085-5
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Reprogramming of Human B Cells from Secreting IgG to IgM by Genome Editing
Authors: Guigao Lin, Kuo Zhang, Yanxi Han, Rongxue Peng, Jiawei Zhang, Dandan Li, Jinming Li
Journal: CRISPR J
PubMed ID: 35900273
Doi: 10.1089/crispr.2021.0093
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Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis
Authors: Nikola Kenjić, Kathleen M Meneely, Daniel J Wherritt, Melissa C Denler, Timothy A Jackson, Graham R Moran, Audrey L Lamb
Journal: J Am Chem Soc
PubMed ID: 35802469
Doi: 10.1021/jacs.2c03376
Products & Services: Gene Synthesis   
Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice
Authors: Yuning Liu, Hong Xing, Alexis F Ernst, Canna Liu, Christian Maugee, Fumiaki Yokoi, Madepalli Lakshmana, Yuqing Li
Journal: Mol Cell Neurosci
PubMed ID: 35843530
Doi: 10.1016/j.mcn.2022.103756
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