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Ensemble-based, high-throughput virtual screening of potential inhibitor targeting putative farnesol dehydrogenase of Metisa plana (Lepidoptera: Psychidae)

Authors: Anis Nadyra Zifruddin, Mohamad Ariff Mohamad Yusoff, Nur Syatila Abd Ghani, Nor Azlan Nor Muhammad, Kok Wai Lam, Maizom Hassan

Journal: Comput Biol Chem

PubMed ID: 36645937

Doi: 10.1016/j.compbiolchem.2023.107811

Products & Services: DNA Sequencing

A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus

Authors: Jennifer A Jenks, Sharmi Amin, Madeline R Sponholtz, Amit Kumar, Daniel Wrapp, Sravani Venkatayogi, Joshua J Tu, Krithika Karthigeyan, Sarah M Valencia, Megan Connors, Melissa J Harnois, Bhavna Hora, Eric Rochat, Jason S McLellan, Kevin Wiehe, Sallie R Permar

Journal: PLoS Pathog

PubMed ID: 36662906

Doi: 10.1371/journal.ppat.1011107

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The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9

Authors: Charles Bayly-Jones, Bill H T Ho, Corinna Lau, Eleanor W W Leung, Laura D'Andrea, Christopher J Lupton, Susan M Ekkel, Hariprasad Venugopal, James C Whisstock, Tom E Mollnes, Bradley A Spicer, Michelle A Dunstone

Journal: Commun Biol

PubMed ID: 36639734

Doi: 10.1038/s42003-023-04431-y

Products & Services: DNA Sequencing

An OsPRMT5-OsAGO2/miR1875-OsHXK1 module regulates rice immunity to blast disease

Authors: Cong Sheng, Xuan Li, Shengge Xia, Yimai Zhang, Ze Yu, Cheng Tang, Le Xu, Zhaoyun Wang, Xin Zhang, Tong Zhou, Pingping Nie, Ayesha Baig, Dongdong Niu, Hongwei Zhao

Journal: J Integr Plant Biol

PubMed ID: 36511124

Doi: 10.1111/jipb.13430

Products & Services: Protein and Antibody Isolation

Performance evaluation of the Ortho VITROS SARS-CoV-2 Spike-Specific Quantitative IgG test by comparison with the surrogate virus neutralizing antibody test and clinical assessment

Authors: Maika Takahashi, Kaori Saito, Tomohiko Ai, Shuko Nojiri, Abdullah Khasawneh, Faith Jessica Paran, Yuki Horiuchi, Satomi Takei, Takamasa Yamamoto, Mitsuru Wakita, Makoto Hiki, Takashi Miida, Toshio Naito, Kazuhisa Takahashi, Yoko Tabe

Journal: PLoS ONE

PubMed ID: 36693058

Doi: 10.1371/journal.pone.0279779

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A novel secreted protein, NISP1, is phosphorylated by soybean Nodulation Receptor Kinase to promote nodule symbiosis

Authors: Baolan Fu, Zhipeng Xu, Yutao Lei, Ru Dong, Yanan Wang, Xiaoli Guo, Hui Zhu, Yangrong Cao, Zhe Yan

Journal: J Integr Plant Biol

PubMed ID: 36534458

Doi: 10.1111/jipb.13436

Products & Services: Recombinant Proteins

Structural domains of SARS-CoV-2 nucleocapsid protein coordinate to compact long nucleic acid substrates

Authors: Michael Morse, Jana Sefcikova, Ioulia Rouzina, Penny J Beuning, Mark C Williams

Journal: Nucleic Acids Res

PubMed ID: 36533523

Doi: 10.1093/nar/gkac1179

Products & Services: Recombinant Proteins

Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters

Authors: Bart Nieuwenhuis, Elise Laperrousaz, James R Tribble, Joost Verhaagen, James W Fawcett, Keith R Martin, Pete A Williams, Andrew Osborne

Journal: Gene Ther

PubMed ID: 36635457

Doi: 10.1038/s41434-022-00380-z

Products & Services: Plasmid DNA Preparation

Highly efficient and robust π-FISH rainbow for multiplexed in situ detection of diverse biomolecules

Authors: Yingfeng Tao, Xiaoliu Zhou, Leqiang Sun, Da Lin, Huaiyuan Cai, Xi Chen, Wei Zhou, Bing Yang, Zhe Hu, Jing Yu, Jing Zhang, Xiaoqing Yang, Fang Yang, Bang Shen, Wenbao Qi, Zhenfang Fu, Jinxia Dai, Gang Cao

Journal: Nat Commun

PubMed ID: 36707540

Doi: 10.1038/s41467-023-36137-4

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A soluble TLR5 is involved in PBLs activation and antibacterial immunity via TLR5M-MyD88-signaling pathway in tongue sole Cynoglossus semilaevis

Authors: Ji-Xing Feng, Ling Liu, Hong-Ye Wang, Jian Zhang, Xue-Peng Li

Journal: Int J Biol Macromol

PubMed ID: 36634796

Doi: 10.1016/j.ijbiomac.2023.123208

Products & Services: Protein and Antibody Isolation

Diagnostic performance between in-house and commercial SARS-CoV-2 serological immunoassays including binding-specific antibody and surrogate virus neutralization test (sVNT)

Authors: Poramed Winichakoon, Jiraprapa Wipasa, Kriangkrai Chawansuntati, Parichat Salee, Tavitiya Sudjaritruk, Saowaluck Yasri, Chantana Khamwan, Rungnapa Peerakam, Dararat Dankai, Romanee Chaiwarith

Journal: Sci Rep

PubMed ID: 36593231

Doi: 10.1038/s41598-022-26202-1

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Alleviation of Hepatic Steatosis by 4-azidophlorizin via the Degradation of Geranylgeranyl Diphosphate Synthase by the Ubiquitin-Proteasome Pathway in Vivo and in Vitro

Authors: Juan Ye, Yaling Qi, Jiao Chen, Shihu Zhang, Boyuan Liu, Yinjuan Zhao, Xianwen Yuan, Qi Cheng, Yang Yang, Furong Zhang, Hongliang Gao, Haoran Wang, Jing Wu, Feng Zhu, Chaojun Li, Peng Cao, Bin Xue

Journal: Adv Biol (Weinh)

PubMed ID: 36599632

Doi: 10.1002/adbi.202200150

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Human mitochondria require mtRF1 for translation termination at non-canonical stop codons

Authors: Annika Krüger, Cristina Remes, Dmitrii Igorevich Shiriaev, Yong Liu, Henrik Spåhr, Rolf Wibom, Ilian Atanassov, Minh Duc Nguyen, Barry S Cooperman, Joanna Rorbach

Journal: Nat Commun

PubMed ID: 36596788

Doi: 10.1038/s41467-022-35684-6

Products & Services: Molecular Biology Reagents

New Synthetic Operon Vectors for Expressing Multiple Proteins in the Chloroplast

Authors: Jihye Yeon, Stephen M Miller, Wipawee Dejtisakdi

Journal: Genes (Basel)

PubMed ID: 36833295

Doi: 10.3390/genes14020368

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Epitope identification for p53R273C mutant

Authors: Jian Zhang, Minglu Liu, Yin Chen, Zishan Zhou, Ping Wang, Yang Yu, Shunchang Jiao

Journal: Immun Inflamm Dis

PubMed ID: 36705409

Doi: 10.1002/iid3.752

Products & Services: Molecular Biology Reagents

A Search for Tick-Associated, Bronnoya-like Virus Spillover into Sheep

Authors: Bianca Elena Bratuleanu, Cristian Raileanu, Delphine Chrétien, Pablo Guardado-Calvo, Thomas Bigot, Gheorghe Savuta, Sarah Temmam, Marc Eloit

Journal: Microorganisms

PubMed ID: 36677501

Doi: 10.3390/microorganisms11010209

Products & Services: Molecular Biology Reagents

Dwarf Open Reading Frame (DWORF) Gene Therapy Ameliorated Duchenne Muscular Dystrophy Cardiomyopathy in Aged mdx Mice

Authors: Emily D Morales, Yongping Yue, Thais B Watkins, Jin Han, Xiufang Pan, Aaron M Gibson, Bryan Hu, Omar Brito-Estrada, Gang Yao, Catherine A Makarewich, Gopal J Babu, Dongsheng Duan

Journal: J Am Heart Assoc

PubMed ID: 36695318

Doi: 10.1161/JAHA.122.027480

Products & Services: Molecular Biology Reagents

Delineation of the CYP505E subfamily of fungal self-sufficient in-chain hydroxylating cytochrome P450 monooxygenases

Authors: Martha Sophia Smit, Mpeyake Jacob Maseme, Jacqueline van Marwijk, Jasmin Cara Aschenbrenner, Diederik Johannes Opperman

Journal: Appl Microbiol Biotechnol

PubMed ID: 36607403

Doi: 10.1007/s00253-022-12329-8

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Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex

Authors: Zhicheng Cui, Gennaro Napolitano, Mariana E G de Araujo, Alessandra Esposito, Jlenia Monfregola, Lukas A Huber, Andrea Ballabio, James H Hurley

Journal: Nature

PubMed ID: 36697823

Doi: 10.1038/s41586-022-05652-7

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Identification of gluten T cell epitopes driving celiac disease

Authors: Markéta Chlubnová, Asbjørn O Christophersen, Geir Kjetil F Sandve, Knut E A Lundin, Jørgen Jahnsen, Shiva Dahal-Koirala, Ludvig M Sollid

Journal: Sci Adv

PubMed ID: 36696493

Doi: 10.1126/sciadv.ade5800

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Nanoparticle vaccines can be designed to induce pDC support of mDCs for increased antigen display

Authors: Nina Butkovich, Jo Anne Tucker, Aaron Ramirez, Enya Li, Vijaykumar S Meli, Edward L Nelson, Szu-Wen Wang

Journal: Biomater Sci

PubMed ID: 36476811

Doi: 10.1039/d2bm01132h

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Development of a Competitive Enzyme-Linked Immunosorbent Assay Targeting the-p30 Protein for Detection of Antibodies against African Swine Fever Virus

Authors: Junming Zhou, Yanxiu Ni, Dandan Wang, Baochao Fan, Xuejiao Zhu, Jinzhu Zhou, Yiyi Hu, Li Li, Bin Li

Journal: Viruses

PubMed ID: 36680193

Doi: 10.3390/v15010154

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Potential Protective Function of Aβ Monomer on Tauopathies

Authors: Amber L H Gray, Victoria Norman, Damilola S Oluwatoba, Rebecca A Prosser, Thanh D Do

Journal: J Am Soc Mass Spectrom

PubMed ID: 36693165

Doi: 10.1021/jasms.2c00343

Products & Services: Protein and Antibody Isolation

Genetic diversity of Newcastle disease viruses circulating in wild and synanthropic birds in Ukraine between 2006 and 2015

Authors: Iryna V Goraichuk, Anton Gerilovych, Vitaliy Bolotin, Olexii Solodiankin, Kiril M Dimitrov, Oleksandr Rula, Nataliia Muzyka, Oleksandr Mezinov, Borys Stegniy, Olena Kolesnyk, Mary J Pantin-Jackwood, Patti J Miller, Claudio L Afonso, Denys Muzyka

Journal: Front Vet Sci

PubMed ID: 36742982

Doi: 10.3389/fvets.2023.1026296

Products & Services: Protein and Antibody Isolation

Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker

Authors: View ORCID ProfileMartin S. Taylor, Connie Wu, Peter C. Fridy, Yasmeen Senussi, Wen-Chih Cheng, John Heaps, Kei Mori, Limor Cohen, Kelly R. Molloy, Brian T. Chait, Michael Goggins, Irun Bhan, Joseph W. Franses, Xiaoyu Yang, Mary-Ellen Taplin, Xinan Wang, David C. Christiani, Bruce E. Johnson, Matthew Meyerson, Ravindra Uppaluri, Ann Marie Egloff, Elyssa N. Denault, Laura M. Spring, Tian-Li Wang, Ie-Ming Shih, Euihye Jung, Kshitij S. Arora, Lawrence R. Zukerberg, Osman H. Yilmaz, Gary Chi, Bryanna L. Norden, Yuhui Song, Linda Nieman, Aparna R. Parikh, Matthew Strickland, Tomas Mustelin, George Eng, Ömer H. Yilmaz, Ursula A. Matulonis, Steven J. Skates, Bo R. Rueda, Ronny Drapkin, Samuel J. Klempner, Vikram Deshpande, David T. Ting, Michael P. Rout, John LaCava, View ORCID ProfileDavid R. Walt, View ORCID ProfileKathleen H. Burns

Journal: biorxiv

Doi: 10.1101/2023.01.25.525462

Products & Services: Monoclonal Antibody Services

SaaS sRNA promotes Salmonella intestinal invasion via modulating MAPK inflammatory pathway

Authors: Linlin Cai , Yunting Xie , Liangting Shao , Haijing Hu , Xinglian Xu , Huhu Wang , Guanghong Zhou

Journal: Gut Microbes .

PubMed ID: 37158502

Doi: 10.1080/19490976.2023.2211184

Products & Services: Gene Synthesis

Differentially Expressed Genes and Signalling Pathways Regulated by High Selenium Involved in Antioxidant and Immune Functions of Goats Based on Transcriptome Sequencing

Authors: Xu Wang, Chao Ban, Jia-Xuan Li, Qing-Yuan Luo, Ji-Xiao Qin, Yi-Qing Xu, Qi Lu, Xing-Zhou Tian

Journal: Int J Mol Sci

PubMed ID: 36674636

Doi: 10.3390/ijms24021124

Products & Services: Molecular Biology Reagents

Ligand-dependent protein interactions of the juvenile hormone receptor captured in real time

Authors: Sarka Tumova, Marek Jindra

Journal: FEBS J

PubMed ID: 36609881

Doi: 10.1111/febs.16719

Products & Services: Molecular Biology Reagents

CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX

Authors: Jack T Whelan, Ragunath Singaravelu, Fuan Wang, Adrian Pelin, Levi A Tamming, Giuseppe Pugliese, Nikolas T Martin, Mathieu J F Crupi, Julia Petryk, Bradley Austin, Xiaohong He, Ricardo Marius, Jessie Duong, Carter Jones, Emily E F Fekete, Nouf Alluqmani, Andrew Chen, Stephen Boulton, Michael S Huh, Matt Y Tang, Zaid Taha, Elena Scut, Jean-Simon Diallo, Taha Azad, Brian D Lichty, Carolina S Ilkow, John C Bell

Journal: Front Immunol

PubMed ID: 36713447

Doi: 10.3389/fimmu.2022.1050250

Products & Services: Molecular Biology Reagents

Discovery and validation of new Hv1 proton channel inhibitors with onco-therapeutic potential

Authors: Antoun El Chemaly, Vincent Jaquet, Yves Cambet, Aurélie Caillon, Ophélie Cherpin, Alexia Balafa, Karl-Heinz Krause, Nicolas Demaurex

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 36640925

Doi: 10.1016/j.bbamcr.2022.119415

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His-tagged lactate oxidase production for industrial applications using fed-batch fermentation

Authors: Agustina Godino, Marilla Amaranto, Agustina Manassero, Fausto Comba, Martín Alonzo Pérez, Lucio Simonella, Martín Pernigotti, José L Barra

Journal: J Biotechnol

PubMed ID: 36608873

Doi: 10.1016/j.jbiotec.2022.12.011

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Protective Effects of against High-Cholesterol Diet-Induced Fatty Liver and Regulation of Host Gene Expression Profiles

Authors: Tianhua He, Nikita Lykov, Xu Luo, Huiling Wang, Zhanxiang Du, Ziyi Chen, Shitian Chen, Lin Zhu, Ye Zhao, Chimeng Tzeng

Journal: Int J Mol Sci

PubMed ID: 36768377

Doi: 10.3390/ijms24032053

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Generation of RUNX1c-eGFP induced pluripotent stem cell, MUSIi012-A-4, using CRISPR/Cas9

Authors: Pimonwan Srisook, Chuti Laowtammathron, Chanchao Lorthongpanich, Phatchanat Klaihmon, Papussorn Terbto, Supaporn Waeteekul, Yaowalak U-Pratya, Surapol Issaragrisil

Journal: Stem Cell Res

PubMed ID: 36753833

Doi: 10.1016/j.scr.2023.103035

Products & Services: Gene Synthesis

Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation

Authors: Pedro Madrigal, Siwei Deng, Yuliang Feng, Stefania Militi, Kim Jee Goh, Reshma Nibhani, Rodrigo Grandy, Anna Osnato, Daniel Ortmann, Stephanie Brown, Siim Pauklin

Journal: Nat Commun

PubMed ID: 36697417

Doi: 10.1038/s41467-023-36116-9

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Changes in Gene Chromatin Organization during Odontogenic Lineage Specification

Authors: Gokul Gopinathan, Xinmin Zhang, Xianghong Luan, Thomas G H Diekwisch

Journal: Genes (Basel)

PubMed ID: 36672939

Doi: 10.3390/genes14010198

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Hyaluronate decorated polyethylene glycol linked poly(lactide-co-glycolide) nanoparticles encapsulating MUC-1 peptide augmented mucosal immune response in Balb/c mice through inhalation route

Authors: Kiran Jyoti, Garima Malik, Monika Chaudhary, Jitender Madan, Anjoo Kamboj

Journal: Biochim Biophys Acta Gen Subj

PubMed ID: 36731729

Doi: 10.1016/j.bbagen.2023.130317

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Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Authors: Yuanyuan Zhang, Xinyu Zhao, Xiaona Dong, Yuying Zhang, Haixia Zou, Yaoguang Jin, Wei Guo, Peng Zhai, Xu Chen, Alexei Kharitonenkov

Journal: Cell Metab

PubMed ID: 36706758

Doi: 10.1016/j.cmet.2023.01.001

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BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells regulating the lipoxygenase pathway

Authors: Fen Xu, Xiaoyan Zhou, Lan Lin, Jing Xu, Yu Feng, Yuanqiao He, Hua Hao

Journal: Int J Immunopathol Pharmacol

PubMed ID: 38134963

Doi: 10.1177/03946320231223826

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Comparative analysis of allergenicity and predicted linear epitopes in α and β parvalbumin from turbot (Scophthalmus maximus)

Authors: Yuhao Huang, Zhenxing Li, Yeting Wu, Yonghong Li, Siddanakoppalu Pramod, Guanzhi Chen, Wenjia Zhu, Ziye Zhang, Hao Wang, Hong Lin

Journal: J Sci Food Agric

PubMed ID: 36606403

Doi: 10.1002/jsfa.12432

Products & Services: Protein Electrophoresis and Western

Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma

Authors: Wajd N Al-Holou, Hanxiao Wang, Visweswaran Ravikumar, Sunita Shankar, Morgan Oneka, Ziad Fehmi, Roel Gw Verhaak, Hoon Kim, Drew Pratt, Sandra Camelo-Piragua, Corey Speers, Daniel R Wahl, Todd Hollon, Oren Sagher, Jason A Heth, Karin M Muraszko, Theodore S Lawrence, Ana C de Carvalho, Tom Mikkelsen, Arvind Rao, Alnawaz Rehemtulla

Journal: Neoplasia

PubMed ID: 36621024

Doi: 10.1016/j.neo.2022.100872

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MiR-130b modulates the invasive, migratory, and metastatic behavior of leiomyosarcoma

Authors: Laura S Danielson, Maria V Guijarro, Silvia Menendez, Brett Higgins, Qiang Sun, Khushbakhat Mittal, Dorota A Popiolek, Michael Overholtzer, Glyn D Palmer, Eva Hernando

Journal: PLoS ONE

PubMed ID: 36701370

Doi: 10.1371/journal.pone.0278844

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Redox-dependent Igfbp2 signaling controls Brca1 DNA damage response to govern neural stem cell fate

Authors: Weam S Shahin, Shima O Ebed, Scott R Tyler, Branko Miljkovic, Soon H Choi, Yulong Zhang, Weihong Zhou, Idil A Evans, Charles Yeaman, John F Engelhardt

Journal: Nat Commun

PubMed ID: 36707536

Doi: 10.1038/s41467-023-36174-z

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ABT1 modifies SMARD1 pathology via interactions with IGHMBP2 and stimulation of ATPase and helicase activity

Authors: Gangadhar P Vadla, Sara M Ricardez Hernandez, Jiude Mao, Mona O Garro-Kacher, Zachary C Lorson, Ronin P Rice, Sarah A Hansen, Christian L Lorson, Kamal Singh, Monique A Lorson

Journal: JCI Insight

PubMed ID: 36480289

Doi: 10.1172/jci.insight.164608

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Spike-mediated viral membrane fusion is inhibited by a specific anti-IFITM2 monoclonal antibody

Authors: Anna Basile , Carla Zannella , Margot De Marco , Giuseppina Sanna , Gianluigi Franci , Massimiliano Galdiero , Aldo Manzin , Vincenzo De Laurenzi , Massimiliano Chetta , Alessandra Rosati , Maria Caterina Turco , Liberato Marzullo

Journal: Antiviral Res

PubMed ID: 36669656

Doi: 10.1016/j.antiviral.2023.105546

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Structure of monkeypox virus DNA polymerase holoenzyme

Authors: Qi Peng, Yufeng Xie, Lu Kuai, Han Wang, Jianxun Qi, George F Gao, Yi Shi

Journal: Science (New York, N. Y.)

PubMed ID: 36520947

Doi: 10.1126/science.ade6360

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Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47

Authors: Huanhuan Hu, Rongjie Cheng, Yanbo Wang, Xiaojun Wang, Jianzhuang Wu, Yan Kong, Shoubin Zhan, Zhen Zhou, Hongyu Zhu, Ranran Yu, Gaoli Liang, Qingyan Wang, Xiaoju Zhu, Chen-Yu Zhang, Rong Yin, Chao Yan , Xi Chen

Journal: The Journal of clinical investigation

PubMed ID: 36413402

Doi: 10.1172/JCI153470

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Identification of B-Cell Epitopes on Capsid Protein Reveals Two Potential Neutralization Mechanisms in Red-Spotted Grouper Nervous Necrosis Virus

Authors: Zhiqi Zhang, Jing Xing, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan

Journal: J Virol

PubMed ID: 36633407

Doi: 10.1128/jvi.01748-22

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Deciphering functional roles and interplay between Beclin1 and Beclin2 in autophagosome formation and mitophagy

Authors: Justin M Quiles, Rita H Najor, Eileen Gonzalez, Monica Jeung, Wenjing Liang, Sarah M Burbach, Erika A Zumaya, Rachel Y Diao, Mark A Lampert, Åsa B Gustafsson

Journal: Sci Signal

PubMed ID: 36719945

Doi: 10.1126/scisignal.abo4457

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The establishment of multiple knockout mutants of Colletotrichum orbiculare by CRISPR-Cas9 and Cre-loxP systems

Authors: Kohji Yamada, Toya Yamamoto, Kanon Uwasa, Keishi Osakabe, Yoshitaka Takano

Journal: Fungal Genet Biol

PubMed ID: 36669556

Doi: 10.1016/j.fgb.2023.103777

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Investigating the Sequence Specific Adsorption Behavior of Polypeptides at the Solid/Liquid Interface

Authors: Christopher S O'Bryan, Timothy J Murdoch, Daniel J Strickland, Katie A Rose, Denis Bendejacq, Daeyeon Lee, Russell J Composto