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Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis

Authors: Huixiang Ma, Tucan Chen, Chengxu Li, Hao Xu, Qingyu Feng, Yunfei Su, Jianqiu Cai, Qingfu Zhu, Fei Liu, Liang Hu

Journal: Ocul Surf

PubMed ID: 38122863

Doi: 10.1016/j.jtos.2023.12.005

Products & Services: Molecular Biology Reagents

Salidroside attenuates myocardial remodeling in DOCA-salt-induced mice by inhibiting the endothelin 1 and PI3K/AKT/NFκB signaling pathways

Authors: Qiao Liu, Qingman Luo, Bin Zhong, Kecheng Tang, Xueling Chen, Shengqian Yang, Xiaohui Li

Journal: Eur J Pharmacol

PubMed ID: 38048979

Doi: 10.1016/j.ejphar.2023.176236

Products & Services: Catalog Antibodies

Akt may associate with insulin-responsive vesicles via interaction with sortilin

Authors: Nava Zaarur, Anatoli B Meriin, Maneet Singh, Raghuveera K Goel, Joseph Zaia, Konstantin V Kandror

Journal: FEBS Lett

PubMed ID: 38105115

Doi: 10.1002/1873-3468.14790

Products & Services: Catalog Peptides

The potential of lactose to inhibit cereulide biosynthesis of emetic Bacillus cereus in milk

Authors: Yin Zheng, Wenxing Xu, Hui Guo, Shubo Yu, Liang Xue, Moutong Chen, Jumei Zhang, Zhenlin Xu, Qingping Wu, Juan Wang, Yu Ding

Journal: Int J Food Microbiol

PubMed ID: 38096676

Doi: 10.1016/j.ijfoodmicro.2023.110517

Products & Services: Protein and Antibody Isolation

Lateralized response of skull bone marrow via osteopontin signaling in mice after ischemia reperfusion

Authors: Chaoran Xu, Qia Zhang, Yi Zhang, Huaijun Chen, Tianchi Tang, Junjie Wang, Siqi Xia, Gao Chen, Jianmin Zhang

Journal: J Neuroinflammation

PubMed ID: 38071333

Doi: 10.1186/s12974-023-02980-x

Products & Services: Protein and Antibody Isolation

Development of a rapid assay for β-etherase activity using a novel chromogenic substrate

Authors: Itzel Celeste Romero-Soto, Jorge A Rodríguez, Vicente Paúl Armenta-Pérez, Raúl Balam Martínez-Pérez, Rosa María Camacho-Ruiz, Leociley Rocha Alencar Menezes, Guilherme Lanzi Sassaki, Arquimedes Santana-Filho, María Angeles Camacho-Ruiz

Journal: Talanta

PubMed ID: 38091749

Doi: 10.1016/j.talanta.2023.125501

Products & Services: Codon Optimization

High-fidelity large-diversity monoclonal mammalian cell libraries by cell cycle arrested recombinase-mediated cassette exchange

Authors: Chuan Chen, Zening Wang, Minhyo Kang, Ki Baek Lee, Xin Ge

Journal: Nucleic Acids Res

PubMed ID: 37941133

Doi: 10.1093/nar/gkad1001

Products & Services: Protein and Antibody Isolation

In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma

Authors: Qiang Cheng, Lukas Farbiak, Amogh Vaidya, Erick Guerrero, Eunice E Lee, Elysha K Rose, Xu Wang, Joshua Robinson, Sang M Lee, Tuo Wei, William E Miller, Ester Alvarez Benedicto, Xizhen Lian, Richard C Wang, Daniel J Siegwart

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38109533

Doi: 10.1073/pnas.2313009120

Products & Services: Protein and Antibody Isolation

Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor

Authors: Masaru Goto, Natsumi Sakamoto, Shoko Higashi, Rena Kawata, Kazuki Nagatsu, Ryota Saito

Journal: J Enzyme Inhib Med Chem

PubMed ID: 37259593

Doi: 10.1080/14756366.2023.2219038

Products & Services: Protein and Antibody Isolation

Bu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway

Authors: Hui Zhang, Huihua Wang, Qing Zhang, Hui Wang, Yuhang Zhu, Fangfang Wang, Jun Lin, Jue Zhou, Fan Qu

Journal: Pharm Biol

PubMed ID: 37655754

Doi: 10.1080/13880209.2023.2249193

Products & Services: Protein and Antibody Isolation

Chromosome recombination and modification by LoxP-mediated evolution in Vibrio natriegens using CRISPR-associated transposases

Authors: Jiaqi Xu, Yijie Sun, Jianping Wu, Sheng Yang, Lirong Yang

Journal: Biotechnol Bioeng

PubMed ID: 38131162

Doi: 10.1002/bit.28639

Products & Services: Gene Synthesis

SAXS/WAXS data of conformationally flexible ribose binding protein

Authors: Jagrity Choudhury, Kento Yonezawa, Anu Anu, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Data Brief

PubMed ID: 38178847

Doi: 10.1016/j.dib.2023.109932

Products & Services: Molecular Biology Reagents

A naturally occurring HA-stabilizing amino acid (HA1-Y17) in an A(H9N2) low-pathogenic influenza virus contributes to airborne transmission

Authors: Xiangjie Sun, Jessica A Belser, Joanna A Pulit-Penaloza, Nicole Brock, Troy J Kieran, Hui Zeng, Claudia Pappas, Terrence M Tumpey, Taronna R Maines

Journal: MBio

PubMed ID: 38112470

Doi: 10.1128/mbio.02957-23

Products & Services: Recombinant Proteins

Discovery of GPX4 inhibitors through FP-based high-throughput screening

Authors: Yu Cao, Bin Wu, Ying Xu, Mingchen Wang, Xinyu Wu, Xiaochen Liang, Jin Lin, Zhihai Li, Hua Lin, Cheng Luo, Shijie Chen

Journal: Eur J Med Chem

PubMed ID: 38145603

Doi: 10.1016/j.ejmech.2023.116044

Products & Services: Catalog Peptides

HERPUD1 governs tumor cell mitochondrial function via inositol 1,4,5-trisphosphate receptor-mediated calcium signaling

Authors: Felipe Paredes, Mario Navarro-Marquez, Clara Quiroga, Danica Jiménez-Gallegos, Samantha M Yeligar, Valentina Parra, Marioly Müller, Mario Chiong, Andrew F G Quest, Alejandra San Martin, Sergio Lavandero

Journal: Free Radic Biol Med

PubMed ID: 38043868

Doi: 10.1016/j.freeradbiomed.2023.11.022

Products & Services: Protein and Antibody Isolation

Photosensitizer-singlet oxygen sensor conjugated silica nanoparticles for photodynamic therapy and bioimaging

Authors: Jeladhara Sobhanan, Kenji Ono, Takuya Okamoto, Makoto Sawada, Paul S Weiss, Vasudevanpillai Biju

Journal: Chem Sci

PubMed ID: 38332815

Doi: 10.1039/d3sc03877g

Products & Services: Molecular Biology Reagents

Circ_0000115 Protects Against Cerebral Ischemia Injury by Suppressing Neuronal Apoptosis, Oxidative Stress and Inflammation by miR-1224-5p/Nos3 Axis In Vitro

Authors: Ying Cao, Yanbing Xu, Rui Zhang, Junsheng Qi, Qiuyu Su, Zhiqiang Chen

Journal: Mol Biotechnol

PubMed ID: 38151617

Doi: 10.1007/s12033-023-01005-5

Products & Services: Molecular Biology Reagents

Antibodies to D7L salivary proteins as a new serological tool to estimate human exposure to mosquitoes

Authors: Sophana Chea, Laura Willen, Sreynik Nhek, Piseth Ly, Kristina Tang, James Oristian, Roberto Salas-Carrillo, Aiyana Ponce, Paola Carolina Valenzuela Leon, Dara Kong, Sokna Ly, Ratanak Sath, Chanthap Lon, Rithea Leang, Rekol Huy, Christina Yek, Jesus G Valenzuela, Eric Calvo, Jessica E Manning, Fabiano Oliveira

Journal: medrxiv

PubMed ID: 38318204

Doi: 10.1101/2023.12.22.23300438

Products & Services: Protein and Antibody Isolation

Cell cycle status of male and female gametes during Arabidopsis reproduction

Authors: Yoav Voichek, Bohdana Hurieva, Caroline Michaud, Anna Schmücker, Zaida Vergara, Bénédicte Desvoyes, Crisanto Gutierrez, Viktoria Nizhynska, Benjamin Jaegle, Michael Borg, Frédéric Berger, Magnus Nordborg, Mathieu Ingouff

Journal: Plant Physiol

PubMed ID: 37757882

Doi: 10.1093/plphys/kiad512

Products & Services: Gene Synthesis

Targeted mutagenesis of the β-strand DNA binding region of African swine fever virus histone-like protein (pA104R) impairs DNA-binding activity and antibody recognition

Authors: Ana Catarina Urbano, Nicolas Ferreira, Nuno Jordão, Fernando Boinas, Carlos Martins, Fernando Ferreira

Journal: Antiviral Res

PubMed ID: 38103699

Doi: 10.1016/j.antiviral.2023.105784

Products & Services: Molecular Biology Reagents

Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization

Authors: Tong Ye, Zhouguang Jiao, Xin Li, Zhanlong He, Yanyan Li, Fengmei Yang, Xin Zhao, Youchun Wang, Weijin Huang, Meng Qin, Yingmei Feng, Yefeng Qiu, Wenhui Yang, Lingfei Hu, Yaling Hu, Yu Zhai, Erqiang Wang, Di Yu, Shuang Wang, Hua Yue, Yishu Wang, Hengliang Wang, Li Zhu, Guanghui Ma, Wei Wei

Journal: Nature

PubMed ID: 38093012

Doi: 10.1038/s41586-023-06809-8

Products & Services: Molecular Biology Reagents

The p30 protein of the African swine fever virus behaves as an RNase

Authors: Satyendu Nandy, Nilave Ranjan Bora, Shubham Gaurav, Sachin Kumar

Journal: Virology

PubMed ID: 38086285

Doi: 10.1016/j.virol.2023.109967

Products & Services: Molecular Biology Reagents

Suppression of overactive IGF-1 attenuates trauma-induced heterotopic ossification in mice

Authors: Dong Mao, Kai Wang, Hong Jiang, Jingyi Mi, Xiaoyun Pan, Gang Zhao, Yongjun Rui

Journal: Am J Pathol

PubMed ID: 38101566

Doi: 10.1016/j.ajpath.2023.11.012

Products & Services: Molecular Biology Reagents

Functional divergence of a bacterial enzyme promotes healthy or acneic skin

Authors: Irshad A Hajam, Madhusudhanarao Katiki, Randall McNally, María Lázaro-Díez, Stacey Kolar, Avradip Chatterjee, Cesia Gonzalez, Mousumi Paulchakrabarti, Biswa Choudhury, J R Caldera, Trieu Desmond, Chih-Ming Tsai, Xin Du, Huiying Li, Ramachandran Murali, George Y Liu

Journal: Nat Commun

PubMed ID: 38052825

Doi: 10.1038/s41467-023-43833-8

Products & Services: Molecular Biology Reagents

High levels of alpha-gal with large variation in the salivary glands of lone star ticks fed on human blood

Authors: L Paulina Maldonado-Ruiz, Kathryn E Reif, Anuradha Ghosh, Stephanie Foré, Rachel L Johnson, Yoonseong Park

Journal: Sci Rep

PubMed ID: 38049505

Doi: 10.1038/s41598-023-48437-2

Products & Services: Molecular Biology Reagents

Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides

Authors: Guillaume Gaud, Sooraj Achar, François X P Bourassa, John Davies, Teri Hatzihristidis, Seeyoung Choi, Taisuke Kondo, Selamawit Gossa, Jan Lee, Paul Juneau, Naomi Taylor, Christian S Hinrichs, Dorian B McGavern, Paul François, Grégoire Altan-Bonnet, Paul E Love

Journal: Nat Immunol

PubMed ID: 38057618

Doi: 10.1038/s41590-023-01725-5

Products & Services: Peptide Synthesis

Generation and Characterization of SORT1-Targeted Antibody-Drug Conjugate for the Treatment of SORT1-Positive Breast Tumor

Authors: Weiliang Zhuang, Wei Zhang, Liping Xie, Lei Wang, Yuan Li, Ziyu Wang, Ao Zhang, Haitao Qiu, Jun Feng, Baohong Zhang, Youjia Hu

Journal: Int J Mol Sci

PubMed ID: 38139459

Doi: 10.3390/ijms242417631

Products & Services: Monoclonal Antibody Services

Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors

Authors: Jody Pacalon, Guillaume Audic, Justine Magnat, Manon Philip, Jérôme Golebiowski, Christophe J Moreau, Jérémie Topin

Journal: Nat Commun

PubMed ID: 38081900

Doi: 10.1038/s41467-023-44058-5

Products & Services: Peptide Synthesis

Enhancing CAR-T cells: unleashing lasting impact potential with phytohemagglutinin activation in in vivo leukemia model

Authors: Berranur Sert, Gamze Gulden, Tarik Teymur, Yasin Ay, Raife Dilek Turan, Onur Mert Unaldi, Elanur Guzenge, Hamza Emir Erdil, Sevim Isik, Pinar Oz, Ilknur Bozkurt, Samed Ozer, Tahire Yurdakul, Osman Kamali, Ercument Ovali, Nevzat Tarhan, Cihan Tastan

Journal: Cancer Gene Ther

PubMed ID: 38092962

Doi: 10.1038/s41417-023-00709-9

Products & Services: Custom Vector Construction

Targeted mutagenesis of the herpesvirus fusogen central helix captures transition states

Authors: Momei Zhou, Benjamin Vollmer, Emily Machala, Muyuan Chen, Kay Grünewald, Ann M Arvin, Wah Chiu, Stefan L Oliver

Journal: Nat Commun

PubMed ID: 38042814

Doi: 10.1038/s41467-023-43011-w

Products & Services: Protein and Antibody Isolation

Structural basis of branching during RNA splicing

Authors: Daniel B Haack, Boris Rudolfs, Cheng Zhang, Dmitry Lyumkis, Navtej Toor

Journal: Nat Struct Mol Biol

PubMed ID: 38057551

Doi: 10.1038/s41594-023-01150-0

Products & Services: Gene Synthesis

Immunoswitch Nanomodulators Enable Active Targeting and Selective Proliferation of Regulatory T Cells for Multiple Sclerosis Therapy

Authors: Xiaoshuang Wang , Zhilin Liu , Di Wang , Yingyu Zhang , Honglei Zhang , Fuxin Xue , Xianhong Wang , Zhaohui Tang , Xuemei Han

Journal: ACS Nano .

PubMed ID: 38113242

Doi: 10.1021/acsnano.3c09225

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Ferricyanide-promoted Oxidative Activation and Ligation of Protein Thioacids in Neutral Aqueous Media

Authors: Guo-Chao Chu, Lu-Jun Liang, Rui Zhao, Yan-Yan Guo, Chun-Tong Li, Chong Zuo, Huasong Ai, Xiao Hua, Zi-Chen Li, Yi-Ming Li, Lei Liu

Journal: CCS Chemistry

Doi: 10.31635/ccschem.023.202303397

Products & Services: Protein and Antibody Isolation

JH degradation pathway participates in hormonal regulation of larval development of Bombyx mori following λ-cyhalothrin exposure

Authors: Yue Su, Wanwan Wang, Yixin Dai, Ruinan Qi, Haoyi Gu, Xiqian Guo, Xinyu Liu, Yuying Ren, Fanchi Li, Bing Li, Haina Sun

Journal: Chemosphere

PubMed ID: 38056714

Doi: 10.1016/j.chemosphere.2023.140871

Products & Services: Monoclonal Antibody Services

Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron-Specific Reactivity in a Vaccination Cohort

Authors: Michael Schoefbaenker, Rieke Neddermeyer, Theresa Guenther, Marlin M Mueller, Marie-Luise Romberg, Nica Classen, Marc T Hennies, Eike R Hrincius, Stephan Ludwig, Joachim E Kuehn, Eva U Lorentzen

Journal: Vaccines (Basel)

PubMed ID: 38140236

Doi: 10.3390/vaccines11121832

Products & Services: Plasmid DNA Preparation

Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis

Authors: Xiaojian Shi, Marisa DeCiucis, Kariona A Grabinska, Jean Kanyo, Adam Liu, Tukiet T Lam, Hongying Shen

Journal: Mol Cell

PubMed ID: 38157846

Doi: 10.1016/j.molcel.2023.12.008

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tRF-1:30-Gly-CCC-3 inhibits thyroid cancer via binding to PC and modulating metabolic reprogramming

Authors: Bifei Fu, YuMing Lou, Xiaofeng Lu, Zhaolin Wu, Junjie Ni, Cong Jin, Pu Wu, Chaoyang Xu

Journal: Life Sci Alliance

PubMed ID: 38081642

Doi: 10.26508/lsa.202302285

Products & Services: Protein and Antibody Isolation

Humoral and cellular immunogenicity and efficacy of a coxsackievirus A10 vaccine in mice

Authors: Huan-Huan An, Meng Li, Rui-Lun Liu, Jie Wu, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Sha-Sha Qian, Shuo Shen

Journal: Emerg Microbes Infect

PubMed ID: 36373411

Doi: 10.1080/22221751.2022.2147022

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Tumor-Reactive CD8+ T Cells Enter a TCF1+PD-1- Dysfunctional State

Authors: Jessica J Roetman, Megan M Erwin, Michael W Rudloff, Natalie R Favret, Carlos R Detrés Román, Minna K I Apostolova, Kristen A Murray, Ting-Fang Lee, Youngmin A Lee, Mary Philip

Journal: Cancer Immunol Res

PubMed ID: 37844197

Doi: 10.1158/2326-6066.CIR-22-0939

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Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule

Authors: Yi-Wen Wu, Wei-Chun HuangFu, Tony Eight Lin, Chao-Hsiang Peng, Huang-Ju Tu, Ting-Yi Sung, Tzu-Ying Sung, Shih-Chung Yen, Shiow-Lin Pan, Kai-Cheng Hsu

Journal: Int J Biol Macromol

PubMed ID: 38163507

Doi: 10.1016/j.ijbiomac.2023.129074

Products & Services: ORF cDNA Clones/MolecularCloud

Injectable CNPs/DMP1-loaded self-assembly hydrogel regulating inflammation of dental pulp stem cells for dentin regeneration

Authors: Yue Zhao, Lutong Song, Mengchen Li, Haoran Peng, Xinyi Qiu, Yuyang Li, Bijun Zhu, Chao Liu, Shuangshuang Ren, Leiying Miao

Journal: Mater Today Bio

PubMed ID: 38170028

Doi: 10.1016/j.mtbio.2023.100907

Products & Services: Protein and Antibody Isolation

Interaction between membrane curvature sensitive factors SpoVM and SpoIVA in Bicelle condition

Authors: Jiali Chen, Yifan Wang, Shuru Lin, Quanxiang Yu, Zhengfei Qi, Wenqi Jiang, Qiang Zhao, Qingshan Bill Fu

Journal: Biochem Biophys Res Commun

PubMed ID: 38141557

Doi: 10.1016/j.bbrc.2023.149395

Products & Services: Recombinant Proteins

Molecular characterization and functional analysis of peroxiredoxin 1 (Prx1) from roughskin sculpin (Trachidermus fasciatus)

Authors: Yingying Liu, Haiyan Cong, Caihong Bi, Haidong Zha, Shanshan Yu, Lihua Zhao, Qian Zhu

Journal: Fish Physiol Biochem

PubMed ID: 38103084

Doi: 10.1007/s10695-023-01281-7

Products & Services: Molecular Biology Reagents

Systemic treatment with ubiquitin carboxy terminal hydrolase L1 TAT protein ameliorates axonal injury and reduces functional deficits after traumatic brain injury in mice

Authors: Zhiping Mi, Jie Ma, Dennis J Zeh, Marie E Rose, Jeremy J Henchir, Hao Liu, Xiecheng Ma, Guodong Cao, C Edward Dixon, Steven H Graham

Journal: Exp Neurol

PubMed ID: 38092186

Doi: 10.1016/j.expneurol.2023.114650

Products & Services: Protein and Antibody Isolation

Design and Engineering of Light-Induced Base Editors Facilitating Genome Editing with Enhanced Fidelity

Authors: Yangning Sun, Qi Chen, Yanbing Cheng, Xi Wang, Zixin Deng, Fuling Zhou, Yuhui Sun

Journal: Adv Sci (Weinh)

PubMed ID: 38039441

Doi: 10.1002/advs.202305311

Products & Services: Gene Synthesis

Use of recombinant malate dehydrogenase (MDH) and superoxide dismutase (SOD) [CuZn] as antigens in indirect ELISA for diagnosis of bovine brucellosis

Authors: Rafaella Silva Andrade, Angélica Rosa Faria, Hélida Monteiro Andrade, Júlio Sílvio de Sousa Bueno Filho, Herman Sander Mansur, Alexandra Ancelmo Piscitelli Mansur, Andrey Pereira Lage, Elaine Maria Seles Dorneles

Journal: J Microbiol Methods

PubMed ID: 38101579

Doi: 10.1016/j.mimet.2023.106874

Products & Services: Recombinant Proteins

Covalent PROTAC design method based on a sulfonyl pyridone probe

Authors: Qinhong Luo , Yaqi Wang , Zhanfeng Hou , Huiting Liang , Licheng Tu , Yun Xing , Chuan Wan , Jianbo Liu , Rui Wang , Lizhi Zhu , Wei Han , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li

Journal: Chem Commun (Camb) .

PubMed ID: 38054347

Doi: 10.1039/d3cc05127g

Products & Services: Gene Synthesis

Molecular basis of Spns2-facilitated sphingosine-1-phosphate transport

Authors: Bin Pang , Leiye Yu , Tong Li , Haizhan Jiao , Xiaomei Wu , Jinxin Wang , Ruiping He , Yurou Zhang , Juan Wang , Hongli Hu , Wei Dai , Li Chen , Ruobing Ren

Journal: Cell Res .

PubMed ID: 38123824

Doi: 10.1038/s41422-023-00908-x

Products & Services: Catalog Gene Editing

Inhalation of taraxasterol loaded mixed micelles for the treatment of idiopathic pulmonary fibrosis

Authors: Tong Zhang , Chao Sun , Shubin Yang , Zimin Cai , Sifeng Zhu , Wendian Liu , Yun Luan , Cheng Wang

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2023.109248

Products & Services: Recombinant Proteins

A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine

Authors: Wenming Liu , Hengchun Li , Bo Liu , Tianxing Lv , Chenchen Yang , Si Chen , Liqiang Feng , Liangxue Lai , Ziyuan Duan , Xinwen Chen , Pingchao Li , Suhua Guan , Ling Chen

Journal: Emerg Microbes Infect .

PubMed ID: 37401832

Doi: 10.1080/22221751.2023.2233643

Products & Services: Peptide Synthesis