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A low-molecular-weight α-glucan from edible fungus Agaricus blazei Murrill activates macrophage TFEB-mediated antibacterial defense to combat implant-associated infection
Authors: Qishan Wang , Yuehong Wang , Yihao Liu , Kai Yuan , Yixuan Lin , Xian Qian , Hongyan Pei , Liangliang Weng , Kaijian Fan , Yihe Hu , Yiqi Yang
Journal: Carbohydrate Polymers
Doi: 10.1016/j.carbpol.2024.122659
Spatiotemporal coordination of antigen presentation and co-stimulatory signal for enhanced anti-tumor vaccination
Authors: Sha Peng , Yumeng Yan , Kenji Ogino , Guanghui Ma , Yufei Xia
Journal: Journal of controlled release
PubMed ID: 39153722
Doi: 10.1016/j.jconrel.2024.08.025.
Products & Services: Peptoid Synthesis   
Rupatadine-inhibited OTUD3 promotes DLBCL progression and immune evasion through deubiquitinating MYL12A and PD-L1
Authors: Ying Sui , Ziyang Shen, Xiaoyou Li 1, Ya Lu , SiTong Feng , Rong Ma, Jianzhong Wu , Changwen Jing, Zhuo Wang, Jifeng Feng , Haixia Cao
Journal: Cell death & disease
PubMed ID: 39097608
Doi: 10.038/s41419-024-06941-x
Human mitochondrial carriers of the SLC25 family function as monomers exchanging substrates with a ping-pong kinetic mechanism
Authors: Camila Cimadamore-Werthein , Martin S King , Denis Lacabanne , Eva Pyrihová , Stephany Jaiquel Baron , Edmund Rs Kunji
Journal: EMBO J
PubMed ID: 38937634
Doi: 10.1038/s44318-024-00150-0.
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siRNA nanoparticle targeting Usp20 lowers lipid levels and ameliorates metabolic syndrome in mice
Authors: Yi Ding 1, Qiu-Bing Chen , Hui Xu , Dilare Adi , Yi-Wen Ding , Wen-Jun Luo , Wen-Zhuo Zhu , Jia-Chen Xu , Xiaolu Zhao , Xiong-Jie Shi , Jie Luo , Hao Yin , Xiao-Yi Lu
Journal: Journal of lipid research
PubMed ID: 39173829
Doi: 10.1016/j.jlr.2024.100626
Products & Services: Custom RNAi Services   
Channelrhodopsins with distinct chromophores and binding patterns
Authors: Yuanyue Shan , Liping Zhao , Meiyu Chen , Xiao Li , Mingfeng Zhang , Duanqing Pei
Journal: Nature Communications
PubMed ID: 39181878
Doi: 10.1038/s41467-024-51811-x
hypocretin-1/hypocretin receptor 1 regulates neuroplasticity and cognitive function through hippocampal lactate homeostasis in depressed model
Authors: Bing Chen , Kangyu Jin , Jingyi Dong , Shangping Cheng , Lingzhuo Kong , Shaohua Hu , Zuobing Chen, Jing Lu
Journal: Advanced Science
PubMed ID: 39119889
Doi: 10.1002/advs.202405354
Anattachment glycoprotein nanoparticle elicits broadly neutralizing antibodies and protects against lethal Nipah virus infection
Authors: Dan Zhou , Rao Cheng , Yanfeng Yao , Gan Zhang , Xin Li , Bingjie Wang , Yong Wang , Feiyang Yu , Shangyu Yang , Hang Liu , Ge Gao , Yun Peng , Miaoyu Chen , Zengqin Deng , Haiyan Zhao
Journal: npj Vaccines
PubMed ID: 39217188
Doi: 10.1038/s41541-024-00954-5
Cellular N-Myristoyl Transferases Are Required for Mammarenavirus Multiplication
Authors: Haydar Witwit , Carlos Alberto Betancourt , Beatrice Cubitt , Roaa Khafaji , Heinrich Kowalski , Nathaniel Jackson , Chengjin Ye , Luis Martinez-Sobrido , Juan C de la Torre
Journal: Viruses
PubMed ID: 39339839
Doi: 10.3390/v16091362
Products & Services: Catalog Antibody   
Dynamics and implications of anti-drug antibodies against adalimumab using ultra-sensitive and highly drug-tolerant assays
Authors: Xiaoliang Ding, Ling Xue, Mingjun Wang, Shengxiong Zhu, Kouzhu Zhu, Sheng Jiang, Jian Wu, Liyan Miao
Journal: Frontiers in Immunology
PubMed ID: 39238635
Doi: 10.3389/fimmu.2024.1429544
Products & Services: Catalog Antibody   
Highly sensitive and selective electrochemical biosensor using odorant-binding protein to detect aldehydes
Authors: Cong Peng a b, Yutong Sui a, Chaohua Fang a, Hongxu Sun a, Wenxin Liu a, Xinying Li a, Chen Qu a, Wenhui Li a, Jiemin Liu a c, Chuandong Wu a
Journal: Analytica Chimica Acta
Doi: 10.1016/j.aca.2024.342932
Products & Services: PCR Cloning and Subcloning   
CLASP-mediated competitive binding in protein condensates directs microtubule growth
Authors: Xuanyan Jia , Leishu Lin, Siqi Guo , Lulu Zhou , Gaowei Jin , Jiayuan Dong , Jinman Xiao , Xingqiao Xie , Yiming Li , Sicong He , Zhiyi Wei , Cong Yu
Journal: Nature Communications
PubMed ID: 39095354
Doi: 10.1038/s41467-024-50863-3
Simultaneous In Vivo Imaging of Neutrophil Elastase and Oxidative Stress in Atherosclerotic Plaques Using a Unimolecular Photoacoustic Probe
Authors: Yuan Ma , Hui Cao , Baode Chen , Xinyu Xu , Qingpeng Zhang , Haoming Chen , Xiao-Bing Zhang , Guosheng Song
Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
PubMed ID: 39115358
Doi: 10.1002/anie.202411840
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A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection
Authors: Xuanxiu Ren # 1, Jiawen Sun # 2 3, Wenhua Kuang # 2, Feiyang Yu 1, Bingjie Wang 1, Yong Wang 2 3, Wei Deng 2 3, Zhao Xu 2 3, Shangyu Yang 1, Hualin Wang 2 4, Yangbo Hu 2 4, Zengqin Deng 5 6, Yun-Jia Ning 7 8, Haiyan Zhao
Journal: Nature Communications
PubMed ID: 39147753
Doi: 10.1038/s41467-024-51108-z
Lipid synthesis, triggered by PPARγ T166 dephosphorylation, sustains reparative function of macrophages during tissue repair
Authors: Shiman Zuo , Yuxin Wang , Hanjing Bao , Zehui Zhang , Nanfei Yang , Meng Jia , Qing Zhang , Ani Jian , Rong Ji , Lidan Zhang , Yan Lu , Yahong Huang , Pingping Shen
Journal: Nature Communications
PubMed ID: 39179603
Doi: doi.org/10.1038/s41467-024-51736-5
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Zinc Coordination Lipid Nanoparticles Co-Delivering Calcium Peroxide and Chelating STING agonist for Enhanced Cancer Metalloimmunotherapy
Authors: Qian Qiu , Jiexin Li , He Ren , Jingyu Zhang , Gengqi Liu , Ruiqi Yang , Boyang Sun , Chen Zhang , Yumiao Zhang
Journal: Small
PubMed ID: 39114869
Doi: 10.1002/smll.202402308
Products & Services: Recombinant Proteins   
Large-scale genomic investigation of pediatric cholestasis reveals a novel hepatorenal ciliopathy caused by PSKH1 mutations
Authors: Sateesh Maddirevula , Mohammad Shagrani , Ae-Ri Ji , Christopher R Horne , Samuel N Young , Lucy J Mather , Mashael Alqahtani , Colin McKerlie , Geoffrey Wood , Paul K Potter , Firdous Abdulwahab , Tarfa AlSheddi , Wendy L van der Woerd , Koen L I van Gassen , Dalal AlBogami , Kishwer Kumar , Ali Syed Muhammad Akhtar , Hiba Binomar , Fowzan S Alkuraya
Journal: GENETICS IN MEDICINE
PubMed ID: 39132680
Doi: 10.1016/j.gim.2024.101231
Products & Services: Peptide Synthesis   
Reversibly photoswitchable protein assemblies with collagen affinity for in vivo photoacoustic imaging of tumors
Authors: Shuai Chen , Kaixin Li , Xin Chen , Shan Lei , Jing Lin , Peng Huang
Journal: Science Advances
PubMed ID: 39213344
Doi: 10.1126/sciadv.adn8274
Products & Services: Codon Optimization   
OPALIN is an LGI1 receptor promoting oligodendrocyte differentiation
Authors: Xiao-Yu Teng , Ping Hu , Cai-Ming Zhang , Qin-Xin Zhang , Guolin Yang , Yan-Yu Zang , Zhi-Xiong Liu , Guiquan Chen , Yun Stone Shi
Journal: Proceedings of the National Academy of Sciences of the United States of America
PubMed ID: 39083419
Doi: 10.1073/pnas.2403652121
Products & Services: Catalog Antibody   
A Minimalist Pathogen-Like Sugar Nanovaccine for Enhanced Cancer Immunotherapy
Authors: Yu Miao , Le Niu , Xinying Lv , Qiang Zhang , Zhisheng Xiao , Zhaoxin Ji , Linfu Chen , Yi Liu , Nanhui Liu , Junjie Zhu , Yang Yang , Qian Chen
Journal: ADVANCED MATERIALS
PubMed ID: 39210649
Doi: 10.1002/adma.202410715
Products & Services: Peptide Synthesis   
Peptide degrader-based targeting of METTL3/14 improves immunotherapy response in cutaneous melanoma
Authors: Hong Han , Zenghui Li , Yuqing Feng , He Song , Zhixiong Fang , Dingxiao Zhang , Dan Yuan , Junfeng Shi
Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
PubMed ID: 39136347
Doi: doi.org/10.1002/anie.202407381
Products & Services: Recombinant Proteins   
The Effects of the Carrier and Ligand Spatial Conformation on RNA Nanodrug Cell Delivery
Authors: Zhuang Zhang , Siying Li , Hongda Wang , Yuping Shan
Journal: Analytical Chemistry
PubMed ID: 39096242
Doi: 10.1021/acs.analchem.4c02270
Products & Services: Peptide Synthesis   
Enzyme-Dynamic Extracellular Vesicles for Metalloimmunotherapy of Malignant Pleural Effusions
Authors: Jiexin Li , Ruiqi Yang , Fuqiang Dong , Qian Qiu , Zhen Jiang , He Ren , Chen Zhang , Gengqi Liu , Jonathan F Lovell , Yumiao Zhang
Journal: ACS Nano
PubMed ID: 39109520
Doi: 10.1021/acsnano.3c12375
Products & Services: Recombinant Proteins   
A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites
Authors: Dimuthu Angage, Jill Chmielewski, Janesha C Maddumage, Eva Hesping, Sabrina Caiazzo, Keng Heng Lai, Lee Ming Yeoh, Joseph Menassa, D Herbert Opi, Callum Cairns, Hamsa Puthalakath, James G Beeson, Marc Kvansakul, Justin A Boddey, Danny W Wilson, Robin F Anders, Michael Foley
Journal: Nat Commun
PubMed ID: 39174515
Doi: 10.1038/s41467-024-50770-7
Products & Services: Gene Synthesis   
Identification of endothelial protein C receptor as a novel druggable agonistic target for reendothelialization promotion and thrombosis prevention of eluting stent
Authors: Jing Chen , Changyi Zhou , Weilun Fang , Jiasheng Yin , Jian Shi , Junbo Ge , Li Shen , Shi-Ming Liu , Shao-Jun Liu
Journal: Bioactive Materials
Doi: doi.org/10.1016/j.bioactmat.2024.07.028
Products & Services: Peptide Synthesis   
Lytic transglycosylase Slt of Pseudomonas aeruginosa as a periplasmic hub protein
Authors: Luis F Avila-Cobian, Stefania De Benedetti, Hidekazu Hoshino, Van T Nguyen, Amr M El-Araby, Safaa Sader, Daniel D Hu, Sara L Cole, Choon Kim, Jed F Fisher, Matthew M Champion, Shahriar Mobashery
Journal: Protein Sci
PubMed ID: 38864725
Doi: 10.1002/pro.5038
Products & Services: Molecular Biology Reagents   
The strongest protein binder is surprisingly labile
Authors: Alba Fernandez-Calvo, Antonio Reifs, Laura Saa, Aitziber L Cortajarena, David De Sancho, Raul Perez-Jimenez
Journal: Protein Sci
PubMed ID: 38864696
Doi: 10.1002/pro.5030
Products & Services: Molecular Biology Reagents   
Fluorinated Titanium Oxide (TiO2-xFx) Nanospindles as Ultrasound-Triggered Pyroptosis Inducers to Boost Sonodynamic Immunotherapy
Authors: Shumin Sun , Xuan Huang , Nailin Yang , Huali Lei , Zifan Pei , Zhihui Han , Lin Liu , Fei Gong , Qiao Yu , Jingrui Li , Youdong Chen , Liang Cheng
Journal: ACS Nano
PubMed ID: 39010657
Doi: 10.1021/acsnano.4c05448
Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection
Authors: Michael J Peluso, Dylan Ryder, Robert R Flavell, Yingbing Wang, Jelena Levi, Brian H LaFranchi, Tyler-Marie Deveau, Amanda M Buck, Sadie E Munter, Kofi A Asare, Maya Aslam, Walter Koch, Gyula Szabo, Rebecca Hoh, Monika Deswal, Antonio E Rodriguez, Melissa Buitrago, Viva Tai, Uttam Shrestha, Scott Lu, Sarah A Goldberg, Thomas Dalhuisen, Joshua J Vasquez, Matthew S Durstenfeld, Priscilla Y Hsue, J Daniel Kelly, Nitasha Kumar, Jeffrey N Martin, Aruna Gambhir, Ma Somsouk, Youngho Seo, Steven G Deeks, Zoltan G Laszik, Henry F VanBrocklin, Timothy J Henrich
Journal: Sci Transl Med
PubMed ID: 38959327
Doi: 10.1126/scitranslmed.adk3295
Products & Services: Molecular Biology Reagents   
Fit-for-purpose heterodivalent single-domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile
Authors: Everardo R Rodriguez Rodriguez, Rune Thorbjørn Nordvang, Marcus Petersson, Jakob Kræmmer Haar Rendsvig, Emma Wenzel Arendrup, Monica L Fernández Quintero, Timothy P Jenkins, Andreas H Laustsen, Sandra Wingaard Thrane
Journal: Protein Sci
PubMed ID: 38923049
Doi: 10.1002/pro.5035
Engineering psychrophilic polymerase for nanopore long-read sequencing
Authors: Yaping Sun , Danny Hsu Ko , Jie Gao , Kang Fu , Yuanchen Mao , Yun He , Hui Tian
Journal: Front Bioeng Biotechnol
PubMed ID: 39011153
Doi: 10.3389/fbioe.2024.1406722
Products & Services: PCR Cloning and Subcloning   
Force-regulated chaperone activity of BiP/ERdj3 is opposite to their homologs DnaK/DnaJ
Authors: Souradeep Banerjee, Debojyoti Chowdhury, Soham Chakraborty, Shubhasis Haldar
Journal: Protein Sci
PubMed ID: 38864739
Doi: 10.1002/pro.5068
Products & Services: Molecular Biology Reagents   
Improvement and application of vacuum-infiltration system in tomato
Authors: Xinghao Yao, Ayat Taheri, Hang Liu, Yaojie Zhang, Ling Li, Jin Shao, Ke Wu, Qing Miao, Weizhi He, Xinyi Hu, Kexuan Tang
Journal: Horticulture research
Doi: doi.org/10.1093/hr/uhae197
Products & Services: Plasmid DNA Preparation   
Optimizing the Design and Geometry of T Cell-Engaging Bispecific Antibodies Targeting CEA in Colorectal Cancer
Authors: Abdullah Elsayed, Louis Plüss, Larissa Nideroest, Giulia Rotta, Marina Thoma, Nathan Zangger, Frederik Peissert, Stefanie K Pfister, Christian Pellegrino, Sheila Dakhel Plaza, Roberto De Luca, Markus G Manz, Annette Oxenius, Emanuele Puca, Cornelia Halin, Dario Neri
Journal: Mol Cancer Ther
PubMed ID: 38638035
Doi: 10.1158/1535-7163.MCT-23-0766
Products & Services: Gene Synthesis   
Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system
Authors: Danping Zhang 1, Liyang Du 1, Haishan Gao 2 3, Cai Yuan 4, Zhonghui Lin 1
Journal: Nucleic Acids Res
PubMed ID: 38967023
Doi: 10.1093/nar/gkae569
Products & Services: Gene Synthesis   
The adaptor protein ECAP, the corepressor LEUNIG, and the transcription factor BEH3 interact and regulate microsporocyte generation in Arabidopsis
Authors: Lei Shi, Changjiang Li, Gaofeng Lv, Xing Li, Wutao Feng, Yujing Bi, Wenhui Wang, Youqun Wang, Lei Zhu, Wenqiang Tang, Ying Fu
Journal: Plant Cell
PubMed ID: 38526222
Doi: 10.1093/plcell/koae086
Products & Services: Gene Synthesis   
Evaluation of combination vaccines targeting transmission of Plasmodium falciparum and P. vivax
Authors: Yi Cao 1, Clifford T H Hayashi , Maisa da Silva Araujo , Abhai K Tripathi , Alice Oliveira Andrade , Jansen Fernandes Medeiros , Joseph Vinetz & Nirbhay Kumar
Journal: Vaccine
PubMed ID: 39033079
Doi: 10.1016/j.vaccine.2024.07.041
Products & Services: Codon Optimization   
Cytochrome b5 diversity in green lineages preceded the evolution of syringyl lignin biosynthesis
Authors: Xianhai Zhao, Yunjun Zhao, Qing-Yin Zeng, Chang-Jun Liu
Journal: Plant Cell
PubMed ID: 38657101
Doi: 10.1093/plcell/koae120
Products & Services: Gene Synthesis   
Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale
Authors: Ruiwen Zhang , Zhou He , Yajing Shi , Xiangkun Sun , Xinyu Chen , Guoquan Wang , Yizhou Zhang , Pan Gao , Ying Wu , Shuhan Lu , Junyi Duan , Shangwu Sun , Na Yang , Wei Fan , Kaitao Zhao , Bei Yang , Yuchen Xia , Yan Zhang , Ying Zhang , Hao Yin
Journal: Cell
PubMed ID: 38936359
Doi: 10.1016/j.cell.2024.05.056
Products & Services: Custom RNAi Services   
Mechanisms Ensuring Fidelity of Family X DNA Polymerases in Programmed DNA rearrangements in Paramecium tetraurelia
Authors: Antonin Nourisson, Sophia Missoury, Ahmed Haouz, Marc Delarue
Journal: biorxiv
Doi: 2024.07.26.605286
Products & Services: Gene Synthesis   
Impact of Equilibrative Nucleoside Transporters TgAT1, TgENT1, and TgENT3 on Toxoplasma gondii Infection and Differentiation
Authors: Amber Goerner, Gabriel Messina, Lea Drogalis Beckham, Bruno Martorelli Di Genova
Journal: biorxiv
Doi: doi.org/10.1101/2024.07.10.601519
Products & Services: Gene Synthesis   
Regulatory Peptide Encoded by the Primary Transcript of miR396a Influences Gene Expression and Root Development in Solanum lycopersicum
Authors: Zhengjie Wang, Ruili Lv, Chenglin Su, Yan Li, Sizhe Fang, Ruirui Yang, Jiaxuan Zhu, Ruiming Wang, Jun Meng, Yushi Luan
Journal: J Agric Food Chem
PubMed ID: 38994823
Doi: 10.1021/acs.jafc.4c03588
Products & Services: Peptide Synthesis   
Comparative biochemistry of PET hydrolase-carbohydrate-binding module fusion enzymes on a variety of PET substrates
Authors: Andrew Philip Rennison , Andreas Prestel , Peter Westh , Marie Sofie Møller
Journal: Enzyme and Microbial Technology
PubMed ID: 39047349
Doi: 10.1016/j.enzmictec.2024.110479
Products & Services: Gene Synthesis   Mutagenesis Services   
Mechanism of ceramide synthase inhibition by fumonisin B1
Authors: Zike Zhang 1 2 4, Qi Fang 1 2 4, Tian Xie 1 2, Xin Gong
Journal: Structure
Doi: 10.1016/j.str.2024.06.002
Discovery of antimicrobial peptides clostrisin and cellulosin from Clostridium: insights into their structures, co-localized biosynthetic gene clusters, and antibiotic activity
Authors: Moisés Alejandro Alejo Hernandez , Katia Pamela Villavicencio Sánchez , Rosendo Sánchez Morales , Karla Georgina Hernández-Magro Gil, David Silverio Moreno-Gutiérrez , Eddie Guillermo Sanchez-Rueda , Yanet Teresa-Cruz , Brian Choi, Armando Hernández Garcia , Alba Romero-Rodríguez, Oscar Juárez , Siseth Martínez-Caballero , Mario Figueroa , Corina-Diana Ceapă
Journal: Beilstein Journal of Organic Chemistry
PubMed ID: 39109298
Doi: 10.3762/bjoc.20.159
Products & Services: Gene Synthesis   
Acceptors stability modulates the efficiency of post-translational protein N-glycosylation
Authors: Paula M Couto, Carlos M A Guardia, Facundo L Couto, Carlos A Labriola, María S Labanda, Julio J Caramelo
Journal: FASEB J
PubMed ID: 38934375
Doi: 10.1096/fj.202302267R
Integration of validated functional evidence to support the pathogenicity of KCNH2 variants
Authors: Reema W Aljassar, Qianyi Shen, Buthaina Albash, Jamie I Vandenberg, Mohammad A Ebrahim, Chai-Ann Ng
Journal: Genet Med Open
PubMed ID: 39669639
Doi: 10.1016/j.gimo.2024.101868
Products & Services: Gene Synthesis   
Activated Clec4n Neutrophils Aggravate Lung Injury in an Endothelial IGFBP7-Dependent Manner
Authors: Lin-Chao Yu, Rui He, Dao-Xin Wang, Di Qi
Journal: Am J Respir Cell Mol Biol
PubMed ID: 38574235
Doi: 10.1165/rcmb.2024-0017OC
Products & Services: Molecular Biology Reagents   
METTL14 contributes to the progression of nasopharyngeal carcinoma through regulating the stability of AOC1 mRNA
Authors: Changan Hu, Shengguan Song, Shanglong Zhao, Zhen Xue, Xiwen Zhu
Journal: Hereditas
PubMed ID: 38956710
Doi: 10.1186/s41065-024-00317-z
Products & Services: Mutant Libraries   
Screening L-Lysine-Overproducing Escherichia coli Using Artificial Rare Codons and a Rare Codon-Rich Marker
Authors: Shen Li , Tianhao Xu , Xinru Meng , Yujuan Yan , Ying Zhou , Lei Duan , Yulong Tang , Li Zhu & Litao Sun
Journal: Nucleic Acids Research
PubMed ID: 38989624
Doi: doi.org/10.3390/
Products & Services: Gene Synthesis   

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