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Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility

Authors: Sixian Qi, Lifan Wei, Zhan Ding, Feiya Zhong, Sicong Yang, Leibin Wu, Xuan Yang, Bin Kang, Mo Dan, Jianhua Gan, Chunlei Li, Xiaoye Su

Journal: SCIENCE ADVANCES

PubMed ID: 41481737

Doi: 10.1126/sciadv.adu6505

Products & Services: Synthetic Guide RNA

Argonaute-mediated RNA editing selectively repairs point mutations

Authors: Zhiwei Zhang, Jinyue Wang, Tongyu Guo, Xiaolan Yu, Fei Wang, Hang Zhang, Yang Liu, Wenqiang Li, Yibin Cheng, Yanhong Peng, Guangbo Yan, Jiakai Cui, Lixin Ma

Journal: Nucleic Acids Research

PubMed ID: 41495892

Doi: 10.1093/nar/gkaf1403

Products & Services: Molecular Biology Reagents

Structural evolution of the selectivity clamp confers ADPR-PP specificity in Namat, a phage nicotinamide ADP-ribose transferase

Authors: Meimei Lan, Li Xu, Yizhen Han, Tong Cui, Zhi Qiao, Yan-Bin Teng, Na Wang, Hongyu Bao

Journal: Nucleic Acids Research

PubMed ID: 41495901

Doi: 10.1093/nar/gkaf1492

Products & Services: Gene Synthesis

Structure and function of the nairovirus cap-snatching endonuclease

Authors: Wenhua Kuang, Zhenhua Tian, Gan Zhang, Fan Wu, Jinyue Li, Jingjing Tang, Huanyu Zhang, Xinyue Zhuo, Zhihong Hu, Manli Wang, Haiyan Zhao, Zengqin Deng

Journal: Nucleic Acids Research

PubMed ID: 41533578

Doi: 10.1093/nar/gkaf1515

Products & Services: Protein and Antibody Isolation

Strategic variations in sarbecovirus and merbecovirus Nsp1 linker regions for translation inhibition

Authors: Ruixi Yan, Mingbo Wu, Xiangyu Ge, Qianqian Jin, Moyu Wang, Haolong Zhou, Yan Li, Yue Wang, Shuai Yuan

Journal: Nucleic Acids Research

PubMed ID: 41538319

Doi: 10.1093/nar/gkag017

Products & Services: Protein and Antibody Isolation

From Natural Discovery to AI-Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Authors: Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu

Journal: Advanced Science

PubMed ID: 41486594

Doi: 10.1002/advs.202516600

Structure-Guided Engineering of a Cas12i Nuclease Unlocks Near-PAMless Genome Editing

Authors: Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian-Kang Zhu

Journal: Advanced Science

PubMed ID: 41532605

Doi: 10.1002/advs.202516670

Products & Services: Synthetic Guide RNA

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS-STING Activation for Cancer Immunotherapy

Authors: Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang

Journal: Advanced Science

PubMed ID: 41560305

Doi: 10.1002/advs.202518356

Products & Services: Protein Electrophoresis and Western

A High Soluble-Fibre Allele in Wheat Encodes a Defective Cell Wall Peroxidase Responsible for Dimerization of Ferulate Moieties on Arabinoxylan

Authors: Rowan A C Mitchell, Ondrej Kosik, Abdul Kader Alabdullah, Anneke Prins, Maria Oszvald, Till K Pellny, Jackie Freeman, Kirstie Halsey, Caroline A Sparks, Alison Huttly, James Brett, Michelle Leverington-Waite, Simon Griffiths, Peter R Shewry, Alison Lovegrove

Journal: Plant Biotechnology Journal

PubMed ID: 41482806

Doi: 10.1111/pbi.70527

Products & Services: Gene Synthesis

Chemical inhibition of a bacterial immune system

Authors: Zhiyu Zang; Olivia K. Duncan; Dziugas Sabonis; Iana Fedorova; Yun Shi; Gause Miraj; Shuai Le; Jun Deng; Yuhao Zhu; Yanyao Cai; Chengqian Zhang; Garima Arya; Shelley A. H. Dixon; Steven P. Angus; Breck A. Duerkop; Haihua Liang; Robert H. Pepin; Thomas Ve; Joseph Bondy-Denomy; Giedre Tamulaitiene; Joseph P. Gerdt

Journal: Cell Host & Microbe

PubMed ID: 41619738

Doi: 10.1016/j.chom.2026.01.003

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

Authors: Juliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams

Journal: Communications Biology

PubMed ID: 41053501

Doi: 10.1038/s42003-025-08819-w

A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

Products & Services: Catalog Antibodies

The ubiquitin ligase KLHL6 drives resistance to CD8+ T cell dysfunction

Authors: Hongcheng Cheng, Yapeng Su, Xiaoli Pan, Yue Xu, Ermei Xie, Jing Du, Daniel G Chen, Xiaomeng Dai, Raphael Gottardo, Philip D Greenberg, Guideng Li

Journal: Nature

PubMed ID: 41535474

Doi: 10.1038/s41586-025-09926-8

The visual system of the longest-living vertebrate, the Greenland shark

Authors: Lily G Fogg, Emily Tom, Maxime Policarpo, William Cho, Fangyuan Gao, Doreen Hii, Aaron E Fawcett, Nicolas Boileau, Amalie Bech-Poulsen, Kirstine F Steffensen, Cherlyn J Ng, Peter G Bushnell, John Fleng Steffensen, Richard Brill, Walter Salzburger, Dorota Skowronska-Krawczyk

Journal: Nature Communications

PubMed ID: 41491153

Doi: 10.1038/s41467-025-67429-6

Products & Services: Peptide Synthesis

Restoration of ovarian endocrine function with encapsulated immune-isolated human ovarian xenograft in ovariectomized mice

Authors: Margaret A Brunette, Monica A Rionda, Delaney Sinko, Jordan H Machlin, Gabrielle M Blevins, Marisa Leo, Ansen Tan, Bipasha Ray, Marilia Cascalho, Vasantha Padmanabhan, Ariella Shikanov

Journal: SCIENCE ADVANCES

PubMed ID: 41477848

Doi: 10.1126/sciadv.adx6348

Products & Services: Peptide Synthesis

Safeguarding genome integrity: Polo-like kinase Cdc5 and phosphatase Cdc14 orchestrate Topoisomerase II-mediated catenane resolution in mitosis

Authors: Lucia F Massari, Alice Finardi, Clara Visintin, Erika Calabrese, Ambra Dondi, Rosella Visintin

Journal: Nucleic Acids Research

PubMed ID: 41533572

Doi: 10.1093/nar/gkaf1509

Products & Services: Chemicals

DNA binding and dimerization of the SOG1 NAC domain are functionally linked with its ability to undergo liquid–liquid phase separation

Authors: Kim Mignon, Rani Van der Eecken, Margot Galle, Manon Demulder, Joris Van Lindt, Lieven De Veylder, Henri De Greve, Remy Loris

Journal: Nucleic Acids Research

PubMed ID: 41556342

Doi: 10.1093/nar/gkaf1522

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AI-Based D-Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug-Resistant Bacterial Infection

Authors: Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li

Journal: Advanced Science

PubMed ID: 41532671

Doi: 10.1002/advs.202518522

Products & Services: Peptide Synthesis

A Modular Vaccine Platform Against SARS-CoV-2 Based on Self-Assembled Protein Nanoparticles

Authors: Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji-Joon Song, Meehyein Kim, Sangyong Jon

Journal: Advanced Science

PubMed ID: 41532509

Doi: 10.1002/advs.202513431

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Functional and Mechanistic Investigation of a Distinct DUF6895 Family Epimerase Involved in Lasso Peptide Modification

Authors: Menghan Shi, Yuwei Duan, Shao-Yang Hou, Liangxu Xie, Weifeng Sun, Liubin Feng, Youming Zhang, Xiaoying Bian, and Guannan Zhong

Journal: ACS catalysis

Doi: 10.1021/acscatal.5c08590

Products & Services: Peptide Synthesis

In Vivo Generation and Manipulation of CAR-T-mimicking Cells via Magnetic Bispecific Nano-antibody for Solid Tumor Therapy

Authors: Yueqiang Zhu, Chaoran Chen, Junbin Chen, Miao Su, Wanling Huang, Sichen Liu, Mingda Yang, Chengqiong Mao, Song Shen, Xianzhu Yang, Jun Wang

Journal: Advanced materials (Deerfield Beach, Fla.)

PubMed ID: 41495981

Doi: 10.1002/adma.202520493

Products & Services: Recombinant Proteins

Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes

Authors: S Haydar, R Bednarz, P Laurette, I Sobitov, N Díaz I Pedrosa, P Videm, T Lueneburg, S Kuß, H Lahm, M Dreßen, M Krane, C Schmidt, B A Grüning, N Voigt, K Streckfuss-Bömeke, R Gilsbach

Journal: Nature Communications

PubMed ID: 41526351

Doi: 10.1038/s41467-025-67220-7

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Wnt3a promotes in situ dentin formation through NKD1- MSX1 axis-mediated odontogenic differentiation of dental pulp stem cells

Authors: Haoran Du, Qiong Li, Chenchen Zhou, Junji Xu, Kang Gao, Zixiao Li, Yifan Xu, Ousheng Liu, Bing Li, Jianguang Xu, Jingsong Wang, Hideaki Kagami, Xianqi Li, Su Chen, Jian Zhou

Journal: International journal of oral science

PubMed ID: 41526338

Doi: 10.1038/s41368-025-00406-3

Products & Services: Protein Electrophoresis and Western

A CLOCK-targeting lncRNA induces trained immunity against tuberculosis

Authors: Shanshan Yu, Qiyao Chai, Zhe Lu, Changgen Qiu, Yanzhao Zhong, Yiru Wang, Zehui Lei, Lihua Qiang, Yingxu Fang, Xinwen Zhang, Bingxi Li, Mengqiu Gao, Lingqiang Zhang, Gong Cheng, Jing Wang, Cui Hua Liu, Yu Pang

Journal: Cell Host & Microbe

PubMed ID: 41475336

Doi: 10.1016/j.chom.2025.12.002

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Screening for novel variable domains of the heavy chains of heavy-chain antibodies targeting different epitopes of thrombomodulin and Luminex fluorescence immunoassay for soluble thrombomodulin

Authors: Congcong Jia, Min Zhu, Yuelan He, Meixiang Yu, Xinyi Xia, Weiwei Ji, Xiang Cao, Jianzhong Lu, Hai Zhang

Journal: International Journal of Biological Macromolecules

PubMed ID: 41314569

Doi: 10.1016/j.ijbiomac.2025.149289

Products & Services: Gene Synthesis Peptide Synthesis

Characterization and therapy of fertilization failure in murine and human models with HNRNPR mutations

Authors: Shiming Gan, Yangyang Li, Lin Yin, Xiaotong Yang, Chen Lou, Sisi Li, Mingde Lin, Xin Li, Wenchao Xu, Jiaming Zhou, Peiran Hu, Zhendong Yao, Yuan Yuan, Jianzhong Sheng, Chen Zhang, Wei Yang, Youjiang Li, Hefeng Huang

Journal: EMBO Molecular Medicine

PubMed ID: 41618099

Doi: 10.1038/s44321-026-00374-z

Products & Services: Protein Electrophoresis and Western

Ependymoglial cells are critical for cortex regeneration in axolotls

Authors: Sulei Fu, Yan-Yun Zeng, Cheng Peng, Liqun Wang, Yuxian Feng, Kun Wang, Yanmei Liu, Ji-Feng Fei

Journal: Nature Communications

PubMed ID: 41559073

Doi: 10.1038/s41467-026-68538-6

Products & Services: Gene Synthesis

Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Authors: Tyler N. Starr; Allison J. Greaney; Cameron M. Stewart; Alexandra C. Walls; William W. Hannon; David Veesler; Jesse D. Bloom; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok; Marco Vignuzzi; Chris Ka Pun Mok

Journal: PLOS Pathogens

PubMed ID: 36399443

Doi: 10.1371/journal.ppat.1010951

Molecular mechanism of ziresovir targeting the fusion glycoprotein of respiratory syncytial virus

Authors: Mengrong Yan; Jingjing Zou; Zhao Gao; Haiqing Yuan; Jim Zhen Wu; Gang Zou; Fengjiang Liu; Wei Peng

Journal: PLOS Pathogens

PubMed ID: 41576151

Doi: 10.1371/journal.ppat.1013864

Structures of Marburgvirus glycoprotein and its complex with NPC1 receptor

Authors: Gang Ye; Fan Bu; Hailey Turner-Hubbard; Morgan Herbst; Lanying Du; Ge Yang; Bin Liu; Fang Li

Journal: Nature

PubMed ID: 41813895

Doi: 10.1038/s41586-026-10240-0

Products & Services: Gene Synthesis

SARS-CoV-2 Mpro inhibitors from Siphonostegia chinensis : an integrated biophysical and computational study

Authors: Yingjie Ren; Wei Wang; Dai Zhang; Mingliang Zhang; Hui Zhang; Yali Wu; Feiyan Liu; Liuqing Yang; Pan Wang; Lei Chen; Xiaofei Chen; Jinfa Tang; Xianqing Ren

Journal: Frontiers in chemistry

PubMed ID: 42040628

Doi: 10.3389/fchem.2026.1790228

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation

Authors: Ting-Syuan Lin; Jingting Wan; Jingjin He; Shidong Cui; Yun Huang; Bojian Zhang; Hsi-Yuan Huang; Kexin Zhu; Jihang Chen; Tao Zhang; Shangfu Li; Liao Hu; Yongfei Wang; Hsien-Da Huang; Ping Tang; Yang-Chi-Dung Lin

Journal: Pharmaceutics

PubMed ID: 41900810

Doi: 10.3390/pharmaceutics18030324

Products & Services: Protein Electrophoresis and Western

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

Authors: Michael Dominic Sacco; Chunlong Ma; Panagiotis Lagarias; Ang Gao; Julia Alma Townsend; Xiangzhi Meng; Peter Dube; Xiujun Zhang; Yanmei Hu; Naoya Kitamura; Brett Hurst; Bart Tarbet; Michael Thomas Marty; Antonios Kolocouris; Yan Xiang; Yu Chen; Jun Wang

Journal: biorxiv

PubMed ID: 32766590

Doi: 10.1101/2020.07.27.223727

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

Authors: Juliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams

Journal: Communications Biology

PubMed ID: 41053501

Doi: 10.1038/s42003-025-08819-w

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

Authors: Juliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams

Journal: Communications Biology

PubMed ID: 41053501

Doi: 10.1038/s42003-025-08819-w

A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

Products & Services: Catalog Antibodies

A series of pyrimidine-based antifungals with anti-mold activity disrupt ER function in Aspergillus fumigatus

Authors: Martin T. Kelty; Aracely Miron-Ocampo; Sarah R. Beattie

Journal: Microbiology Spectrum

PubMed ID: 38916314

Doi: 10.1128/spectrum.01045-24

Products & Services: Catalog Antibodies

Structure of the lysosomal KICSTOR-GATOR1-SAMTOR nutrient-sensing supercomplex

Authors: Christopher J. Lupton, Charles Bayly-Jones, Shuqi Dong, Terrance Lam, Wentong Luo, Gareth D. Jones, Chantel Mastos, Nicholas J. Frescher, San S. Lim, Alastair C. Keen, Luke E. Formosa, Hari Venugopal, Yong-Gang Chang, Michelle L. Halls, Andrew M. Ellisdon

Journal: Cell

PubMed ID: 41512879

Doi: 10.1016/j.cell.2025.12.005

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Polyamine-dependent metabolic shielding regulates alternative splicing

Authors: Amaia Zabala-Letona, Mikel Pujana-Vaquerizo, Belen Martinez-Laosa, Maria Ponce-Rodriguez, Saioa Garcia-Longarte, Isabel Mendizabal, Ana Gimeno, Malgorzata Rogalska, Joycelyn Tan, Diana Cabrera, Sebastiaan van Liempd, Pilar Ximenez-Embun, Sergio Espinosa, Maider Fagoaga-Eugui, Francesca Peccati, Maciej Zakrzewski, Ianire Astobiza, Mikel Arana-Castañares, Sarah Cherkaoui, Maria Sendino, Inés Martín-Barros, Amaia Ercilla, Laura Bozal-Basterra, Onintza Carlevaris, Amaia Arruabarrena-Aristorena, Encarnación Pérez-Andrés, Telmo Santamaría-Zamorano, Juan A Ferrer-Bonsoms, Fernando Carazo, Maciej Cieśla, Cesar Lobato, Joan Seoane, Natalia Martín-Martín, Rosa Barrio, James D Sutherland, Ana M Aransay, Juan Manuel Falcón-Pérez, Barbara Martínez-Pastor, Angel Rubio, Francisco J Blanco, Michael D Hogarty, Raphael J Morscher, Edurne Berra, Remigiusz A Serwa, Jesús Jiménez-Barbero, Gonzalo Jiménez-Osés, Alejo Efeyan, Lydia Finley, Jose M Lizcano, Javier Muñoz, Juan Valcarcel, Arkaitz Carracedo

Journal: Nature

PubMed ID: 41535471

Doi: 10.1038/s41586-025-09965-1

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A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands

Authors: Shihong Zhang, Tzu-Hao Tang, Sinéad Kinsella, Francesco Mazziotta, Michael T Schweizer, Megan S McAfee, Ariunaa Munkhbat, Yapeng Su, Valentin Voillet, Lauren E Martin, Colton W Smith, Yuta Asano, Menna Hailemariam, Jakob Bakhtiari, Bo Lee, Cecilia Yeung, Hung Chen, Alessandro M Rizzi, Daniel G Chen, Kelsey Furiya, Nick Horst, Tianzi Zhang, Phung Le, Kelly McKenna, Shannon K Oda, Anthony Rongvaux, Phillip D Greenberg, Thomas M Schmitt, Aude G Chapuis

Journal: Nature Communications

PubMed ID: 41484084

Doi: 10.1038/s41467-025-67446-5

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Actomyosin-dependent assembly of the mechanosensitive machinery from adherens junctions triggers actin polymerization and organization

Authors: Aurélie Favarin, Rayan Said, Hong Wang, Emilie Zeine, Amaury Pierrard, Julien Pernier, Hemalatha Narassimprakash, Stéphane Roméro, Alexis M Gautreau, René-Marc Mège, Christophe Le Clainche

Journal: SCIENCE ADVANCES

PubMed ID: 41477870

Doi: 10.1126/sciadv.ady4863

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Dual-receptor targeting of type I dendritic cells with DNA-scaffolded nanoparticles enhances STING-licensed antitumor immunity

Authors: Deblin Jana, Emilia Herdes, Justin Moustouka, Kayla M Mash, Jingge Chen, Kareem Ebeid, Marwa Sallam, Akram Abbasi, Tejal Desai

Journal: SCIENCE ADVANCES

PubMed ID: 41481710

Doi: 10.1126/sciadv.aeb0452

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Allospecific splenic Tr1 cells drive effector T cell exhaustion through up-regulated Areg-EGFR signaling to promote transplant tolerance

Authors: Amar Singh, Adam Herman, Devanjan Dey, Samuel Menge, Shilpi Singh, Anna Tran, Anders Matson, Ahmed Mourad, Parthasarathy Rangarajan, Ravi Masuria, Naoya Sato, Sarah Vadnais, Joseph Sushil Rao, Gatikrushna Singh, Melanie L Graham, Sabarinathan Ramachandran, Bernhard J Hering

Journal: SCIENCE ADVANCES

PubMed ID: 41499508

Doi: 10.1126/sciadv.aea0567

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On-demand cancer immunotherapy via single-cell encapsulation of synthetic circuit–engineered cells

Authors: Yue Zhao, Rui Li, Yirui Han, Chaochen Shi, Kyubae Lee, Guangjun Nie, Yazhou Chen

Journal: SCIENCE ADVANCES

PubMed ID: 41533781

Doi: 10.1126/sciadv.aea3573

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Cell surface engineering with a pseudofibrotic ECM reprograms the antifibrotic activity of mesenchymal stromal cells

Authors: Xianghua Zhong, Xinchao Liu, Jiajia Luo, Xinyang Liu, Xueting Wei, Xi Peng, Lu Wang, Huaimin Wang, Kunyu Zhang, Liming Bian, Peng Shi

Journal: SCIENCE ADVANCES

PubMed ID: 41544160

Doi: 10.1126/sciadv.aea0998

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Enhanced SfaTnpB enables single-base-specific, one-pot nucleic acid detection for high-sensitivity diagnostics

Authors: Bingrong Xu, Sheng Li, Yong Li, Shuhong Zhao, Xinyun Li, Jianlin Han, Di Wu, Shuaicheng Li, Ling Chen, Shengsong Xie, Xiaosong Han, Changzhi Zhao

Journal: Nucleic Acids Research

PubMed ID: 41505099

Doi: 10.1093/nar/gkaf1433

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Bringing the ends together: cryo-EM structures of mycobacterial Ku in complex with DNA define its role in NHEJ synapsis

Authors: Joydeep Baral, Ching-Seng Ang, Paul James McMillan, Kalyan Shobhana, Ayushi Saini, Elizabeth Hinde, Amit Kumar Das, Isabelle Rouiller

Journal: Nucleic Acids Research

PubMed ID: 41521670

Doi: 10.1093/nar/gkaf1418

Products & Services: PCR Cloning and Subcloning

G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails

Authors: Harrison A Fuchs, Yunhui Peng, Shine Ayyapan, Ruben Rosas, Houfang Zhang, Anna R Panchenko, Catherine A Musselman

Journal: Nucleic Acids Research

PubMed ID: 41533587

Doi: 10.1093/nar/gkaf1381

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Multilayered regulation by RNA thermometers enables precise control of Cas9 expression in E. coli

Authors: Elise K Kammerdiener, Sarah K Garcia, Margaret K Bales, Dawn M Klingeman, Adam M Guss, Richard J Giannone, Robert L Hettich, Carrie A Eckert, William G Alexander

Journal: Nucleic Acids Research

PubMed ID: 41533573

Doi: 10.1093/nar/gkaf1495

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Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR-Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Authors: Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo

Journal: Advanced Science

PubMed ID: 41560288

Doi: 10.1002/advs.202514140

Products & Services: Protein Electrophoresis and Western