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页码: 59/1028 每页显示数量

Optimization of an alum-anchored clinical HIV vaccine candidate

Authors: Kristen A Rodrigues, Christopher A Cottrell, Jon M Steichen, Bettina Groschel, Wuhbet Abraham, Heikyung Suh, Yash Agarwal, Kaiyuan Ni, Jason Y H Chang, Parisa Yousefpour, Mariane B Melo, William R Schief, Darrell J Irvine

Journal: npj Vaccines

PubMed ID: 37573422

Doi: 10.1038/s41541-023-00711-0

Products & Services: Recombinant Proteins

Evaluating the effect of food components on the digestion of dietary nucleic acids in human gastric juice in vitro

Authors: Yanfang Zhang, Jingyi Dong, Jingxian Chen, Xiaoming Pan

Journal: Food Sci Nutr

PubMed ID: 37823154

Doi: 10.1002/fsn3.3599

Products & Services: Custom DNA/RNA Oligos

Toward non-factor therapy in hemophilia: an antithrombin insensitive Gla-domainless factor Xa as tissue factor pathway inhibitor bait

Authors: Marie-Claire Dagher, Atanur Ersayin, Landry Seyve, Mathieu Castellan, Cyril Moreau, Luc Choisnard, Nicole Thielens, Raphaël Marlu, Benoît Polack, Aline Thomas

Journal: Res Pract Thromb Haemost

PubMed ID: 37841511

Doi: 10.1016/j.rpth.2023.102175

Products & Services: Combinatorial DNA Libraries

Immobilization of α-transglucosidase on silica-coated magnetic nanoparticles and its application for production of isomaltooligosaccharide from the potato peel

Authors: Rohit Maurya, Usman Ali, Sunaina Kaul, Raja Bhaiyya, Ravindra Pal Singh, Koushik Mazumder

Journal: Sci Rep

PubMed ID: 37543692

Doi: 10.1038/s41598-023-38266-8

Products & Services: Molecular Biology Reagents

CircMIB2 therapy can effectively treat pathogenic infection by encoding a novel protein

Authors: Weiwei Zheng, Linchao Wang, Shang Geng, Liyuan Yang, Xing Lv, Shiying Xin, Tianjun Xu

Journal: Cell Death Dis

PubMed ID: 37652905

Doi: 10.1038/s41419-023-06105-3

Products & Services: Custom RNAi Services

Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1

Authors: Jun-Qi Luo, Tao-Wei Yang, Jun Wu, Hou-Hua Lai, Li-Bin Zou, Wen-Bin Chen, Xu-Min Zhou, Dao-Jun Lv, Sheng-Ren Cen, Zi-Ning Long, Yi-You Mao, Peng-Xiang Zheng, Xiao-Hong Su, Zhi-Yong Xian, Fang-Peng Shu, Xiang-Ming Mao

Journal: Cell Death Dis

PubMed ID: 37542027

Doi: 10.1038/s41419-023-06007-4

Products & Services: Catalog Antibody

The SlWRKY6-SlPROPEP-SlPep module confers tomato resistance to Phytophthora infestans

Authors: Ruirui Yang , Jie Liu , Zhicheng Wang , Lei Zhao , Tingting Xue , Jun Meng , Yushi Luan

Journal: Scientia Horticulturae

Doi: 10.1016/j.scienta.2023.112117

Products & Services: Peptide Synthesis

Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity

Authors: Chao Wang , Jingjing Ding , Qiaodong Wei , Shoukang Du , Xiaobo Gong , Ting Gang Chew

Journal: iScience .

PubMed ID: 37720093

Doi: 10.1016/j.isci.2023.107773

Products & Services: Proteins, Expression, Isolation and Analysis

Using a synthetic machinery to improve carbon yield with acetylphosphate as the core

Authors: Likun Guo , Min Liu , Yujia Bi , Qingsheng Qi, Mo Xian , Guang Zhao

Journal: Nat Commun .

PubMed ID: 37648707

Doi: 10.1038/s41467-023-41135-7

Products & Services: Codon Optimization

Novel "GaEl Antigenic Patches" Identified by a "Reverse Epitomics" Approach to Design Multipatch Vaccines against NIPAH Infection, a Silent Threat to Global Human Health

Authors: Sukrit Srivastava, Michael Kolbe

Journal: ACS Omega

PubMed ID: 37692250

Doi: 10.1021/acsomega.3c01909

Products & Services: Proteins, Expression, Isolation and Analysis

Peripheral substitution effects on unnatural base pairs: A case of brominated TPT3 to enhance replication fidelity

Authors: Bianbian Huo, Chao Wang, Xiaoqi Hu, Honglei Wang, Gongming Zhu, Anlian Zhu, Lingjun Li

Journal: Bioorg Chem

PubMed ID: 37683537

Doi: 10.1016/j.bioorg.2023.106827

Products & Services: Proteins, Expression, Isolation and Analysis

Context-dependent role of Pho binding sites in Polycomb complex recruitment in Drosophila

Authors: Janet Lesley Brown, Joshua D Price, Maksim Erokhin, Judith A Kassis

Journal: Genetics

PubMed ID: 37216193

Doi: 10.1093/genetics/iyad096

Products & Services: Proteins, Expression, Isolation and Analysis

Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting

Authors: Stefania Torino, Mugdha Dhurandhar, Annelore Stroobants, Raf Claessens, Rouslan G Efremov

Journal: Nat Methods

PubMed ID: 37592181

Doi: 10.1038/s41592-023-01967-z

Products & Services: Proteins, Expression, Isolation and Analysis

Enhancement of Neutralization Responses through Sequential Immunization of Stable Env Trimers Based on Consensus Sequences from Select Time Points by Mimicking Natural Infection

Authors: Mingming Wan, Xiao Yang, Jie Sun, Elena E Giorgi, Xue Ding, Yan Zhou, Yong Zhang, Weiheng Su, Chunlai Jiang, Yaming Shan, Feng Gao

Journal: Int J Mol Sci

PubMed ID: 37628824

Doi: 10.3390/ijms241612642

Products & Services: Gene Synthesis

Rice-produced classical swine fever virus glycoprotein E2 with herringbone-dimer design to enhance immune responses

Authors: Qianru Xu, Fanshu Ma, Daichang Yang, Qingmei Li, Liming Yan, Jiquan Ou, Longxian Zhang, Yunchao Liu, Quan Zhan, Rui Li, Qiang Wei, Hui Hu, Yanan Wang, Xueyang Li, Shenli Zhang, Jifei Yang, Shujun Chai, Yongkun Du, Li Wang, Erqin Zhang, Gaiping Zhang

Journal: Plant Biotechnol J

PubMed ID: 37572354

Doi: 10.1111/pbi.14152

Products & Services: Gene Synthesis

Nanoparticles carrying paclitaxel and anti-miR-221 for breast cancer therapy triggered by ultrasound

Authors: Libo Zhang, Zhen Ren, Jinhui Lü, Xinhai Mo, Jie Lin, Ya Li, Wenjing Ma, Pengfei Liu, Yajing Shen, Qian Zhao, Lu Qian, Xiaoxin Cheng, Zuoren Yu, Bo Zhang

Journal: Cell Death Discov

PubMed ID: 37582832

Doi: 10.1038/s41420-023-01594-9

Products & Services: Custom DNA/RNA Oligos

Precision Genome Engineering in Based on a Broad-Host-Range Vector and CRISPR-Cas9 Technology

Authors: Alex Gussak, Maria Laura Ferrando, Mels Schrama, Peter van Baarlen, Jerry Mark Wells

Journal: ACS Synth Biol

PubMed ID: 37602730

Doi: 10.1021/acssynbio.3c00110

Products & Services: Peptide Synthesis

Structure and design of Langya virus glycoprotein antigens

Authors: Zhaoqian Wang, Matthew McCallum, Lianying Yan, William Sharkey, Young-Jun Park, Ha V Dang, Moushimi Amaya, Ashley Person, Christopher C Broder, David Veesler

Journal: biorxiv

PubMed ID: 37645760

Doi: 10.1101/2023.08.20.554025

Products & Services: ORF cDNA Clones/MolecularCloud

Structural mechanism of synergistic targeting of the nucleosome by PU1 and C/EBPα

Authors: Tengfei Lian, Ruifang Guan, Bing-Rui Zhou, Yawen Bai

Journal: biorxiv

PubMed ID: 37790476

Doi: 10.1101/2023.08.25.554718

Products & Services: Gene Synthesis

Stromal cell-derived factor-1 downregulation contributes to neuroprotection mediated by CXC chemokine receptor 4 interactions after intracerebral hemorrhage in rats

Authors: Yu Wu, Zhuwei Zhang, Xiaoou Sun, Jing Wang, Haitao Shen, Xue Sun, Zhong Wang

Journal: CNS Neurosci Ther

PubMed ID: 37614198

Doi: 10.1111/cns.14400

Products & Services: Custom Vector Construction

Origin of the OAS–RNase L innate immune pathway before the rise of jawed vertebrates via molecular tinkering

Authors: Lingyu Chu , Zhen Gong , Wenqiang Wang , Guan-Zhu Han

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 37487089

Doi: 10.1073/pnas.2304687120

Products & Services: Codon Optimization

Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells

Authors: Gladys J Keitany , Benjamin E R Rubin , Meghan E Garrett , Andrea Musa , Jeff Tracy , Yu Liang , Peter Ebert , Amanda J Moore , Jonathan Guan , Erica Eggers , Ninnia Lescano , Ryan Brown , Adria Carbo , Hussein Al-Asadi , Travers Ching , Austin Day , Rebecca Harris , Charles Linkem , Dimitry Popov , Courtney Wilkins , Lianqu Li , Jiao Wang , Chuanxin Liu , Li Chen , Jennifer N Dines , Caroline Atyeo , Galit Alter , Lance Baldo , Anna Sherwood , Bryan Howie , Mark Klinger , Erik Yusko , Harlan S Robins , Sharon Benzeno , Amy E Gilbert

Journal: Cell Chem Biol .

PubMed ID: 37586370

Doi: 10.1016/j.chembiol.2023.07.011

Products & Services: Proteins, Expression, Isolation and Analysis

A near-infrared fluorescence-enhancing plasmonic biosensing microarray identifies soluble PD-L1 and ICAM-1 as predictive checkpoint biomarkers for cancer immunotherapy

Authors: Zhijun Lin, Mengyao Liu, Wei Xing, Fenghua Wang, Hongxia Zhang, Xiaoli Wei, Hans Schmitthenner, Xi Xie, Xiaojun Xia, Jiang Yang

Journal: Biosens Bioelectron

PubMed ID: 37683502

Doi: 10.1016/j.bios.2023.115633

Products & Services: Proteins, Expression, Isolation and Analysis

The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA1, BA2, and BA5

Authors: Huiping Shuai, Jasper Fuk-Woo Chan, Bingjie Hu, Yue Chai, Chaemin Yoon, Huan Liu, Yuanchen Liu, Jialu Shi, Tianrenzheng Zhu, Jing-Chu Hu, Ye-Fan Hu, Yuxin Hou, Xiner Huang, Terrence Tsz-Tai Yuen, Yang Wang, Jinjin Zhang, Yao Xia, Lin-Lei Chen, Jian-Piao Cai, Anna Jinxia Zhang, Shuofeng Yuan, Jie Zhou, Bao-Zhong Zhang, Jian-Dong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Hin Chu

Journal: EBioMedicine

PubMed ID: 37579626

Doi: 10.1016/j.ebiom.2023.104753

Products & Services: Proteins, Expression, Isolation and Analysis

Anti-SARS-CoV-2 Antibody Level Is Associated with a History of COVID-19 Infection and mRNA Vaccination in Patients with Diabetes

Authors: Is Asma'ul Haq Hataul, Nanny Natalia M Soetedjo, Josephine Debora, Marita Restie Tiara, Hofiya Djauhari, Evan Susandi, Bachti Alisjahbana, Rudi Wisaksana, Hikmat Permana

Journal: Vaccines (Basel)

PubMed ID: 37766101

Doi: 10.3390/vaccines11091424

Products & Services: Proteins, Expression, Isolation and Analysis

ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies

Authors: Adam S Chervin, Jennifer D Stone, Iwona Konieczna, Kelly M Calabrese, Ningyan Wang, Dipica Haribhai, Feng Dong, Michael K White, Luis E Rodriguez, Gail T Bukofzer, Paul A Ellis, Cormac Cosgrove, Claudie Hecquet, Jerry D Clarin, Joann P Palma, Edward B Reilly

Journal: Mol Cancer Ther

PubMed ID: 37294945

Doi: 10.1158/1535-7163.MCT-22-0770

Products & Services: Peptide Synthesis

Expression analysis, clinical significance and potential function of PLXNB2 in acute myeloid leukaemia

Authors: Zhibo Guo, Dan Guo, Desheng Kong, Sicheng Bian, Linlin Zhao, Qi Li, Leilei Lin, Jiali Hao, Lili Sun, Yinghua Li

Journal: Mol Biol Rep

PubMed ID: 37632633

Doi: 10.1007/s11033-023-08721-w

Products & Services: Molecular Biology Reagents

NLRC4 promotes the cGAS-STING signaling pathway by facilitating CBL-mediated K63-linked polyubiquitination of TBK1

Authors: Rongzhao Zhang, Wenxian Yang, Huifang Zhu, Jingbo Zhai, Mengzhou Xue, Chunfu Zheng

Journal: J Med Virol

PubMed ID: 37537877

Doi: 10.1002/jmv.29013

Products & Services: Molecular Biology Reagents

Biosynthesis of High-Active Hemoproteins by the Efficient Heme-Supply Pichia Pastoris Chassis

Authors: Fei Yu, Xinrui Zhao, Jingwen Zhou, Wei Lu, Jianghua Li, Jian Chen, Guocheng Du

Journal: Adv Sci (Weinh)

PubMed ID: 37649147

Doi: 10.1002/advs.202302826

Products & Services: Molecular Biology Reagents

Obtaining high yield recombinant Enterococcus faecium nicotinate nucleotide adenylyltransferase for X-ray crystallography and biophysical studies

Authors: Olamide Jeje, Ramesh Pandian, Yasien Sayed, Ikechukwu Achilonu

Journal: Int J Biol Macromol

PubMed ID: 37544558

Doi: 10.1016/j.ijbiomac.2023.126066

Products & Services: Molecular Biology Reagents

Gene co-option, duplication and divergence of cement proteins underpin the evolution of bioadhesives across barnacle life histories

Authors: Yue Him Wong, Niklas Dreyer, HaoCheng Liu, Yi Lan, Jamie J Chen, Jin Sun, Wei-Peng Zhang, Pei-Yuan Qian, Benny K K Chan

Journal: Mol Ecol

PubMed ID: 37584177

Doi: 10.1111/mec.17084

Products & Services: Proteins, Expression, Isolation and Analysis

Correction to: An Immunoinformatics-Based Study of Mycobacterium tuberculosis Region of Difference-2 Uncharacterized Protein (Rv1987) as a Potential Subunit Vaccine Candidate for Preliminary Ex Vivo Analysis

Authors: Aregitu Mekuriaw Arega, Ajit Kumar Dhal, Kali Prasad Pattanaik, Sasmita Nayak, Rajani Kanta Mahapatra

Journal: Appl Biochem Biotechnol

PubMed ID: 37552364

Doi: 10.1007/s12010-023-04668-7

Products & Services: Gene Synthesis

NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis

Authors: Quentin I B Lemaître, Natascha Bartsch, Ian U Kouzel, Henriette Busengdal, Gemma Sian Richards, Patrick R H Steinmetz, Fabian Rentzsch

Journal: Nat Commun

PubMed ID: 37563174

Doi: 10.1038/s41467-023-39789-4

Products & Services: Custom Vector Construction

Role of the CagY antenna projection in Cag type IV secretion system activity

Authors: Sirena C Tran, Mark S McClain, Timothy L Cover

Journal: Infect Immun

PubMed ID: 37638724

Doi: 10.1128/iai.00150-23

Products & Services: Plasmid DNA Preparation

The brassinosteroid-responsive protein OCTOPUS is a novel regulator of immune signaling

Authors: Kaitlyn N Greenwood, Courtney L King, Isabella Melena, Katherine A Stegemann, Maura Donnelly, Anna Childers, Raegan Mozal, Carina A Collins, Benjamin J Spears

Journal: Plant Direct

PubMed ID: 37638229

Doi: 10.1002/pld3.524

Products & Services: Peptide Synthesis

SARS-CoV-2 ORF8 accessory protein is a virulence factor

Authors: M Bello-Perez, J Hurtado-Tamayo, A Z Mykytyn, M M Lamers, R Requena-Platek, D Schipper, D Muñoz-Santos, J Ripoll-Gómez, A Esteban, P J Sánchez-Cordón, L Enjuanes, B L Haagmans, I Sola

Journal: MBio

PubMed ID: 37623322

Doi: 10.1128/mbio.00451-23

Products & Services: Stable Cell Lines

Rapid and ultrasensitive detection of mpox virus using CRISPR/Cas12b-empowered graphene field-effect transistors

Authors: LiWang;ChangXu;ShaohuiZhang ;ShangChen;HaoWang;ZhaojunDuan;OmarA.Al-Hartomy ;SwelmWageh;XiaoshaWen;YiLiu;YiLin;HuijiePu;ZhongjianXie;QuanLiu;HanZhang;DixianLuo

Journal: Applied Physics Reviews

Doi: 10.1063/5.0142494

Products & Services: Gene Synthesis

Flow-cytometric cell sorting coupled with UV mutagenesis for improving pectin lyase expression

Authors: Ke Fang , Jun Ma , Xinyu Wang, Ziting Xu , Ziyang Zhang , Piwu Li , Ruiming Wang, Junqing Wang, Chuying Sun and Ziyang Dong

Journal: Frontiers in bioengineering and biotechnology

Doi: 10.3389/fbioe.2023.1251342

Products & Services: PCR Cloning and Subcloning

Backbone-Installed Split Intein-Assisted Ligation for the Chemical Synthesis of Mirror-Image Proteins

Authors: Baochang Zhang, Yupeng Zheng, Guochao Chu, Xiangyu Deng, Tongyue Wang, Weiwei Shi, Yongkang Zhou, Shan Tang , Ji-Shen Zheng ， Lei Liu

Journal: Angew Chem Int Ed Engl

PubMed ID: 37357888

Doi: 10.1002/anie.202306270

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Enhancement of β-carotene content in Chlamydomonas reinhardtii by expressing bacterium-driven lycopene β-cyclase

Authors: Danqiong Huang , Chenglong Liu , Mingshan Su , Zhiyong Zeng , Chaogang Wang , Zhangli Hu , Sulin Lou , Hui Li

Journal: Biotechnol Biofuels Bioprod .

PubMed ID: 37573357

Doi: 10.1186/s13068-023-02377-1

Products & Services: Gene Synthesis

Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing

Authors: Lenong Li, Xubiao Peng, Mansoor Batliwala, Marlene Bouvier

Journal: Nat Commun

PubMed ID: 37596268

Doi: 10.1038/s41467-023-40736-6

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Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation

Authors: Frederic Morales-Paytuví, Alba Fajardo, Carles Ruiz-Mirapeix, James Rae, Francesc Tebar, Marta Bosch, Carlos Enrich, Brett M Collins, Robert G Parton, Albert Pol

Journal: J Cell Biol

PubMed ID: 37526691

Doi: 10.1083/jcb.202204020

Products & Services: Proteins, Expression, Isolation and Analysis

Interchangeability of the Assays Used to Assess the Activity of Anti-SARS-CoV-2 Monoclonal Antibodies

Authors: Brady T Hickerson, Alexey M Khalenkov, Tao Xie, David M Frucht, Dorothy E Scott, Natalia A Ilyushina

Journal: Viruses

PubMed ID: 37632039

Doi: 10.3390/v15081698

Products & Services: Proteins, Expression, Isolation and Analysis

Variation in microbial feature perception in the Rutaceae family with immune receptor conservation in citrus

Authors: Jessica Trinh, Tianrun Li, Jessica Y Franco, Tania Y Toruño, Danielle M Stevens, Shree P Thapa, Justin Wong, Rebeca Pineda, Emmanuel Ávila de Dios, Tracy L Kahn, Danelle K Seymour, Chandrika Ramadugu, Gitta L Coaker

Journal: Plant Physiol

PubMed ID: 37144828

Doi: 10.1093/plphys/kiad263

Products & Services: Peptide Synthesis

Id-neoantigen vaccine induces therapeutic CD8 T cells against multiple myeloma: H chain-loss escapees cause FLC MM

Authors: Marita Westhrin, Jana Blazevski, Ana Textor, Pegah Abdollahi, Ramakrishna Prabhu Gopalakrishnan, Linda Thuy Ngo, Peter Olaf Hofgaard, Julia Heinzelbecker, Sonja Bobic, Even Fossum, Heidi Cecilie Larsen Spång, Ranveig Braathen, Bjarne Bogen

Journal: J Immunother Cancer

PubMed ID: 37607769

Doi: 10.1136/jitc-2023-006944

Products & Services: Proteins, Expression, Isolation and Analysis

CircRNA-CIRH1A Promotes the Development of Osteosarcoma by Regulating PI3K/AKT and JAK2/STAT3 Signaling Pathways

Authors: Meng Zhang, Xiang Wang, Jianfeng Zhao, Jizhou Yan, Xiaodan He, Danxia Qin, Fang Liang, Kai Tong, Jianjian Wang

Journal: Mol Biotechnol

PubMed ID: 37608076

Doi: 10.1007/s12033-023-00812-0

Products & Services: Custom DNA/RNA Oligos

Stabilisation of the RirA [4Fe-4S] cluster results in loss of iron-sensing function

Authors: Elizabeth Gray, Melissa Y Y Stewart, Libby Hanwell, Jason C Crack, Rebecca Devine, Clare E M Stevenson, Anne Volbeda, Andrew W B Johnston, Juan C Fontecilla-Camps, Matthew I Hutchings, Jonathan D Todd, Nick E Le Brun

Journal: Chem Sci

PubMed ID: 37736639

Doi: 10.1039/d3sc03020b

Products & Services: Gene Synthesis

Neutrophil-Mediated Tumor-Targeting Delivery System of Oncolytic Bacteria Combined with ICB for Melanoma Lung Metastasis Therapy

Authors: Lina Liu, Wenjie Xin, Qiang Li, Baolian Huang, Te Yin, Siqi Hua, Chen Yang, Chen Chen, Chao Han, Zichun Hua

Journal: Adv Sci (Weinh)

PubMed ID: 37565362

Doi: 10.1002/advs.202301835

Products & Services: Gene Synthesis

Soluble SARS-CoV-2 RBD and human ACE2 peptidase domain produced in Drosophila S2 cells show functions evoking virus-cell interface

Authors: Federico Carrión, Florencia Rammauro, Natalia Olivero-Deibe, Martín Fló, María Magdalena Portela, Analía Lima, Rosario Durán, Otto Pritsch, Sergio Bianchi

Journal: Protein Sci

PubMed ID: 37405395

Doi: 10.1002/pro.4721

Products & Services: Gene Synthesis

Garlic-derived exosome-like nanovesicles as a hepatoprotective agent alleviating acute liver failure by inhibiting CCR2/CCR5 signaling and inflammation

Authors: Xin Zhao, Fang Yin, Luoqin Fu, Yingyu Ma, Luyi Ye, Yilin Huang, Weijiao Fan, Wenxue Gao, Yu Cai, Xiaozhou Mou

Journal: Biomater Adv

PubMed ID: 37717364

Doi: 10.1016/j.bioadv.2023.213592

Products & Services: PCR Cloning and Subcloning

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