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Intracerebral Hemorrhage-Induced Brain Injury: the Role of Lysosomal-Associated Transmembrane Protein 5
Authors: Wei Hua, Shuainan Ma, Yuxin Pang, Qi Liu, Yueying Wang, Zhiyi Liu, Nan Zhao, Naixin Ren, Sinan Jin, Benshuai Wang, Yuejia Song, Jiping Qi
Journal: Mol Neurobiol
PubMed ID: 37525083
Doi: 10.1007/s12035-023-03484-8
Products & Services: Molecular Biology Reagents   
Photoexcited cryptochromes interact with ADA2b and SMC5 to promote the repair of DNA double-strand breaks in Arabidopsis
Authors: Tongtong Guo, Minqing Liu, Li Chen, Yao Liu, Ling Li, Yupeng Li, Xiaoli Cao, Zhilei Mao, Wenxiu Wang, Hong-Quan Yang
Journal: Nat Plants
PubMed ID: 37488265
Doi: 10.1038/s41477-023-01461-6
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4 T cells
Authors: Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Christina M Monnie, Muhammad S Alam, Ming Zhou, Melissa Mikolaj, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D Ashwell, Klaus Strebel, Kyung S Lee
Journal: Res Sq
PubMed ID: 37645926
Doi: 10.21203/rs.3.rs-2924123/v1
Products & Services: DNA Sequencing   
Vav1-dependent Rac1 activation mediates hypoxia-induced gemcitabine resistance in pancreatic ductal adenocarcinoma cells through upregulation of HIF-1α expression
Authors: Congyuan Zhu, Hao Hu, Ye Ma, Shuming Xiong, Dongming Zhu
Journal: Cell Biol Int
PubMed ID: 37545183
Doi: 10.1002/cbin.12074
Products & Services: Molecular Biology Reagents   
Structural and functional insights into the modulation of T cell costimulation by monkeypox virus protein M2
Authors: Shangyu Yang , Yong Wang , Feiyang Yu , Rao Cheng , Yiwei Zhang , Dan Zhou , Xuanxiu Ren , Zengqin Deng , Haiyan Zhao
Journal: Nature Communications
PubMed ID: 37626059
Doi: 10.1038/s41467-023-40748-2
Secreted Peptide SpPIP1 Modulates Disease Resistance and Salt Tolerance in Tomato
Authors: Ruirui Yang , Zhicheng Wang , Lei Zhao , Jie Liu , Jun Meng , Yushi Luan
Journal: J Agric Food Chem .
PubMed ID: 37535837
Doi: 10.1021/acs.jafc.3c03412
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Homozygous COQ7 mutation: a new cause of potentially treatable distal hereditary motor neuropathy
Authors: Arnaud Jacquier, Julian Theuriet, Fanny Fontaine, Valentine Mosbach, Nicolas Lacoste, Shams Ribault, Valérie Risson, Julien Carras, Laurent Coudert, Thomas Simonet, Philippe Latour, Tanya Stojkovic, Juliette Piard, Anne Cosson, Gaëtan Lesca, Françoise Bouhour, Stéphane Allouche, Hélène Puccio, Antoine Pegat, Laurent Schaeffer
Journal: Brain
PubMed ID: 36454683
Doi: 10.1093/brain/awac453
Products & Services: Gene Synthesis   
Microbe-induced gene silencing boosts crop protection against soil-borne fungal pathogens
Authors: Han-Guang Wen, Jian-Hua Zhao, Bo-Sen Zhang, Feng Gao, Xue-Ming Wu, Yong-Sheng Yan, Jie Zhang, Hui-Shan Guo
Journal: Nat Plants
PubMed ID: 37653339
Doi: 10.1038/s41477-023-01507-9
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Organelle-dependent polyprotein designs enable stoichiometric expression of nitrogen fixation components targeted to mitochondria
Authors: Jianguo Yang, Nan Xiang, Yiheng Liu, Chenyue Guo, Chenyu Li, Hui Li, Shuyi Cai, Ray Dixon, Yi-Ping Wang
Journal: Proc Natl Acad Sci U S A
PubMed ID: 37585462
Doi: 10.1073/pnas.2305142120
Products & Services: Gene Synthesis   
GmNAC039 and GmNAC018 activate the expression of cysteine protease genes to promote soybean nodule senescence
Authors: Haixiang Yu, Aifang Xiao, Jiashan Wu, Haoxing Li, Yan Duan, Qingshan Chen, Hui Zhu, Yangrong Cao
Journal: Plant Cell
PubMed ID: 37177994
Doi: 10.1093/plcell/koad129
Design, synthesis and evaluation of ursodeoxycholic acid-cinnamic acid hybrids as potential anti-inflammatory agents by inhibiting Akt/NF-κB and MAPK signaling pathways
Authors: Xiaoxue Li, Yue Hu, Bingxin He, Lingyu Li, Yu Tian, Yingjie Xiao, Hai Shang, Zhongmei Zou
Journal: Eur J Med Chem
PubMed ID: 37678142
Doi: 10.1016/j.ejmech.2023.115785
In Vitro and Ex Planta Gold-Bonded and Gold-Mineralized Tobacco Mosaic Virus
Authors: Yifeng Ma, Zhuohong Wu, Nicole F Steinmetz
Journal: Langmuir
PubMed ID: 37540623
Doi: 10.1021/acs.langmuir.3c00688
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Structure/epitope analysis and IgE binding activities of three cyclophilin family proteins from Dermatophagoides pteronyssinus
Authors: Yuwei Li, Xizhuo Sun, Liteng Yang
Journal: Sci Rep
PubMed ID: 37604978
Doi: 10.1038/s41598-023-40720-6
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Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity
Authors: Erdem Aybay, Mamoun Elkhalifa, Srinivas Akula, Sara Wernersson, Lars Hellman
Journal: Dev Comp Immunol
PubMed ID: 37597699
Doi: 10.1016/j.dci.2023.104920
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Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis
Authors: Shihao Xie , Jiaxin Li , Fengyuan Lyu , Qingming Xiong , Peng Gu , Yuqi Chen , Meiling Chen , Jingna Bao , Xianglong Zhang , Rongjuan Wei , Youpeng Deng , Hongzheng Wang , Zhenhua Zeng , Zhongqing Chen , Yongqiang Deng , Zhuoshi Lian , Jie Zhao , Wei Gong , Ye Chen , Ke-Xuan Liu , Yi Duan , Yong Jiang , Hong-Wei Zhou , Peng Chen
Journal: Gut .
PubMed ID: 37553229
Doi: 10.1136/gutjnl-2023-329996
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Crystal structure of domain of unknown function 507 (DUF507) reveals a new protein fold
Authors: Cole E McKay , Jianlin Cheng , John J Tanner
Journal: Sci Rep .
PubMed ID: 37596303
Doi: 10.1038/s41598-023-40558-y
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SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
Authors: Nuno Bastos, Stéphanie A Castaldo, Bárbara Adem, José C Machado, Carlos A Melo, Sonia A Melo
Journal: J Transl Med
PubMed ID: 37641131
Doi: 10.1186/s12967-023-04448-1
Products & Services: Molecular Biology Reagents   
TRIB1 confers therapeutic resistance in GBM cells by activating the ERK and Akt pathways
Authors: Karnika Singh, Chunhua Han, Jessica L Fleming, Aline P Becker, Joseph McElroy, Tiantian Cui, Benjamin Johnson, Ashok Kumar, Ebin Sebastian, Christian A Showalter, Morgan S Schrock, Matthew K Summers, Valesio Becker, Zhen-Yue Tong, Xiaomei Meng, Heather R Manring, Monica Venere, Erica H Bell, Pierre A Robe, A L Grosu, S Jaharul Haque, Arnab Chakravarti
Journal: Sci Rep
PubMed ID: 37528172
Doi: 10.1038/s41598-023-32983-w
Products & Services: DNA Sequencing   
Effectiveness of Bivalent Omicron-Containing Booster Vaccines against SARS-CoV-2 Omicron Variant among Individuals with and without Prior SARS-CoV-2 Infection
Authors: Kristin Widyasari, Jieun Jang, Taejoon Kang, Sunjoo Kim
Journal: Viruses
PubMed ID: 37632098
Doi: 10.3390/v15081756
Products & Services: Monoclonal Antibody Services   
mRNA vaccination boosts S-specific T cell memory and promotes expansion of CD45RA T-like CD8 T cells in COVID-19 recovered individuals
Authors: Koshlan Mayer-Blackwell, Heeju Ryu, Amy S Codd, K Rachael Parks, Hugh R MacMillan, Kristen W Cohen, Terri L Stewart, Aaron Seese, Maria P Lemos, Stephen C De Rosa, Julie L Czartoski, Zoe Moodie, Long T Nguyen, Donald J McGuire, Rafi Ahmed, Andrew Fiore-Gartland, M Juliana McElrath, Evan W Newell
Journal: Cell Rep Med
PubMed ID: 37552991
Doi: 10.1016/j.xcrm.2023.101149
Products & Services: Catalog Peptides   
Anti-Melanogenic and Antioxidant Activity of Bifidobacterium longum Strain ZJ1 Extracts, Isolated from a Chinese Centenarian
Authors: Jing Wu , Funa Zhang , Haixia Yu , Shimei Qi , Yu Wu , Weihua Xiao
Journal: Int J Mol Sci .
PubMed ID: 37628988
Doi: 10.3390/ijms241612810
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Author Correction: mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum
Authors: Clifford T H Hayashi, Yi Cao, Leor C Clark, Abhai K Tripathi, Fidel Zavala, Garima Dwivedi, James Knox, Mohamad-Gabriel Alameh, Paulo J C Lin, Ying K Tam, Drew Weissman, Nirbhay Kumar
Journal: npj Vaccines
PubMed ID: 37567884
Doi: 10.1038/s41541-023-00723-w
Products & Services: Molecular Biology Reagents   
Inactivation influences the extent of inhibition of voltage-gated Ca channels by Gem-implications for channelopathies
Authors: Salma Allam, Rose Levenson-Palmer, Zuleen Chia Chang, Sukhjinder Kaur, Bryan Cernuda, Ananya Raman, Audrey Booth, Scott Dobbins, Gabrielle Suppa, Jian Yang, Zafir Buraei
Journal: Front Physiol
PubMed ID: 37654674
Doi: 10.3389/fphys.2023.1155976
Publisher Correction: High-throughput characterization of HLA-E-presented CD94/NKG2x ligands reveals peptides which modulate NK cell activation
Authors: Brooke D Huisman, Ning Guan, Timo Rückert, Lee Garner, Nishant K Singh, Andrew J McMichael, Geraldine M Gillespie, Chiara Romagnani, Michael E Birnbaum
Journal: Nat Commun
PubMed ID: 37644057
Doi: 10.1038/s41467-023-40946-y
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Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions
Authors: F E M Scholte, E Karaaslan, T J O'Neal, T E Sorvillo, S C Genzer, S R Welch, J D Coleman-McCray, J R Spengler, M H Kainulainen, J M Montgomery, S D Pegan, E Bergeron, C F Spiropoulou
Journal: Front Cell Infect Microbiol
PubMed ID: 37671145
Doi: 10.3389/fcimb.2023.1233148
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Recombinant spike protein vaccines coupled with adjuvants that have different modes of action induce protective immunity against SARS-CoV-2
Authors: Shiho Chiba, Peter J Halfmann, Shun Iida, Yuichiro Hirata, Yuko Sato, Makoto Kuroda, Tammy Armbrust, Samuel Spyra, Tadaki Suzuki, Yoshihiro Kawaoka
Journal: Vaccine
PubMed ID: 37635002
Doi: 10.1016/j.vaccine.2023.08.054
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Mutations in CCNB3 affect its location thus causing a multiplicity of phenotypes in human oocytes maturation by aberrant CDK1 activity and APC/C activity at different stages
Authors: Congjing Wang, Meng Xi Chen, Yuan Zhang, Xue Bai, Qiqi Cao, Jian Han, Nana Zhang, Chun Zhao, Xiufeng Ling, Ximan Rui, Yichun Guan, Junqiang Zhang, Ran Huo
Journal: J Ovarian Res
PubMed ID: 37635245
Doi: 10.1186/s13048-023-01229-8
Products & Services: Molecular Biology Reagents   
Riding the Omicron BA5 Wave: Improved Humoral Response after Vaccination with Bivalent Omicron BA4-5-Adapted mRNA SARS-CoV-2 Vaccine in Chronic Hemodialysis Patients
Authors: Eugen Ovcar, Sammy Patyna, Niko Kohmer, Elisabeth Heckel-Kratz, Sandra Ciesek, Holger F Rabenau, Ingeborg A Hauser, Kirsten de Groot
Journal: Vaccines (Basel)
PubMed ID: 37766105
Doi: 10.3390/vaccines11091428
Products & Services: Molecular Biology Reagents   
RhoB promotes Salmonella survival by regulating autophagy
Authors: Marco Kirchenwitz, Jessica Halfen, Kristin von Peinen, Silvia Prettin, Jana Kollasser, Susanne Zur Lage, Wulf Blankenfeldt, Cord Brakebusch, Klemens Rottner, Anika Steffen, Theresia E B Stradal
Journal: Eur J Cell Biol
PubMed ID: 37703749
Doi: 10.1016/j.ejcb.2023.151358
Optimization and Deoptimization of Codons in SARS-CoV-2 and Related Implications for Vaccine Development
Authors: Xinkai Wu, Ke-Jia Shan, Fuwen Zan, Xiaolu Tang, Zhaohui Qian, Jian Lu
Journal: Adv Sci (Weinh) .
PubMed ID: 37267926
Doi: 10.3390/v16020223
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Target delivery of a PD-1-TREM2 scFv by CAR-T cells enhances anti-tumor efficacy in colorectal cancer
Authors: Jian Chen, Tianchuan Zhu, Guanmin Jiang, Qi Zeng, Zhijian Li, Xi Huang
Journal: Mol Cancer
PubMed ID: 37563723
Doi: 10.1186/s12943-023-01830-x
Products & Services: Gene Synthesis   
Development of a novel ultrasound- and biocrosslinking-enhanced immobilization strategy with application to food enzymes
Authors: Juan Han , Ting Zhang , Zhuoyue Zhou , Houjin Zhang
Journal: Food Chem .
PubMed ID: 36917903
Doi: 10.1016/j.foodchem.2023.135810
Immunogenicity, safety and reactogenicity of heterologous (third dose) booster vaccination with a full or fractional dose of two different COVID-19 vaccines: A phase 4, single-blind, randomized controlled trial in adults
Authors: Sue Ann Costa Clemens, Natalie Marchevsky, Sarah Kelly, Sally Felle, Ahmed Eldawi, Rupetha Rajasingam, Rawan Mahmud, Teresa Lambe, Merryn Voysey, Isabela Gonzalez, Eveline Pipolo Milan, Maria Cleonice Justino, Sagida Bibi, Parvinder Aley, Ralf Clemens, Andrew J Pollard
Journal: Hum Vaccin Immunother
PubMed ID: 37438960
Doi: 10.1080/21645515.2023.2233400
Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1
Authors: Jonathan F Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L Gloor, Samantha Rustichelli, Victoria Godínez-López, Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan Gretarsson, Jonathan M Burg, Allison R Hickman, Lu Sun, Saarang Gopinath, Hailey F Taylor, Zu-Wen Sun, Ryan J Ezell, Anup Vaidya, Matthew J Meiners, Marcus A Cheek, William J Rice, Vladimir Svetlov, Evgeny Nudler, Chao Lu, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache
Journal: Sci Adv
PubMed ID: 37556531
Doi: 10.1126/sciadv.adg9832
Photoaffinity labelling displacement assay using multiple recombinant protein domains
Authors: David J Fallon, Alex Phillipou, Christopher J Schofield, David House, Nicholas C O Tomkinson, Jacob T Bush
Journal: Biochem J
PubMed ID: 37401534
Doi: 10.1042/BCJ20230129
SARS-CoV-2 neutralizing antibody bebtelovimab - a systematic scoping review and meta-analysis
Authors: Mabel Nyit Yi Liew, Kok Pim Kua, Shaun Wen Huey Lee, Kon Ken Wong
Journal: Front Immunol
PubMed ID: 37701439
Doi: 10.3389/fimmu.2023.1100263
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Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells
Authors: Sergio P Alpuche-Lazcano, Matthew Stuible, Bassel Akache, Anh Tran, John Kelly, Sabahudin Hrapovic, Anna Robotham, Arsalan Haqqani, Alexandra Star, Tyler M Renner, Julie Blouin, Jean-Sébastien Maltais, Brian Cass, Kai Cui, Jae-Young Cho, Xinyu Wang, Daria Zoubchenok, Renu Dudani, Diana Duque, Michael J McCluskie, Yves Durocher
Journal: Commun Med (Lond)
PubMed ID: 37612423
Doi: 10.1038/s43856-023-00340-7
Modified mRNA Formulation and Stability for Cardiac and Skeletal Muscle Delivery
Authors: Magdalena M Żak, Keerat Kaur, Jimeen Yoo, Ann Anu Kurian, Matthew Adjmi, Gayatri Mainkar, Seonghun Yoon, Lior Zangi
Journal: Pharmaceutics
PubMed ID: 37765147
Doi: 10.3390/pharmaceutics15092176
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Divergent Pharmacology and Biased Signaling of the Four Melanocortin-4 Receptor Isoforms in Rainbow Trout ()
Authors: Ren-Lei Ji, Ting Liu, Zhi-Shuai Hou, Hai-Shen Wen, Ya-Xiong Tao
Journal: Biomolecules
PubMed ID: 37627313
Doi: 10.3390/biom13081248
Products & Services: Monoclonal Antibody Services   
High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase
Authors: Lu Yang, Tristan Wagner, Ariel Mechaly, Alexandra Boyko, Eduardo M Bruch, Daniela Megrian, Francesca Gubellini, Pedro M Alzari, Marco Bellinzoni
Journal: Nat Commun
PubMed ID: 37563123
Doi: 10.1038/s41467-023-40253-6
High-throughput functional dissection of noncoding SNPs with biased allelic enhancer activity for insulin resistance-relevant phenotypes
Authors: Yuan-Yuan Duan, Xiao-Feng Chen, Ren-Jie Zhu, Ying-Ying Jia, Xiao-Ting Huang, Meng Zhang, Ning Yang, Shan-Shan Dong, Mengqi Zeng, Zhihui Feng, Dong-Li Zhu, Hao Wu, Feng Jiang, Wei Shi, Wei-Xin Hu, Xin Ke, Hao Chen, Yunlong Liu, Rui-Hua Jing, Yan Guo, Meng Li, Tie-Lin Yang
Journal: Am J Hum Genet
PubMed ID: 37506691
Doi: 10.1016/j.ajhg.2023.07.002
Products & Services: Gene Synthesis   
Identification of sucrose synthase from to favor biocatalytic glycosylation
Authors: Kai Chen, Lei Lin, Ruiqi Ma, Jiajie Ding, Huayi Pan, Yehui Tao, Yan Li, Honghua Jia
Journal: Front Microbiol
PubMed ID: 37649634
Doi: 10.3389/fmicb.2023.1220208
Conformational investigation of the asymmetric periplasmic domains of LptBFGC using SDSL CW EPR spectroscopy
Authors: Nicholas P Cina, Candice S Klug
Journal: Appl Magn Reson
PubMed ID: 38645307
Doi: 10.1007/s00723-023-01590-3
Products & Services: Gene Synthesis   
GPCR activation and GRK2 assembly by a biased intracellular agonist
Authors: Jia Duan , Heng Liu , Fenghui Zhao , Qingning Yuan , Yujie Ji , Xiaoqing Cai , Xinheng He , Xinzhu Li , Junrui Li , Kai Wu , Tianyu Gao , Shengnan Zhu , Shi Lin , Ming-Wei Wang , Xi Cheng , Wanchao Yin , Yi Jiang , Dehua Yang , H Eric Xu
Journal: Nature .
PubMed ID: 37532940
Doi: 10.1038/s41586-023-06395-9
A non-toxic recombinant Clostridium septicum α toxin induces protective immunity in mice and rabbits
Authors: Jige Du, Irene Meki, Qianlin Li, Ying Liu, Zhen Zhu, Chenfan Pan, Yingju Xia, Lizhi Fu, Liu Yang, Suhui Zhang, Chunsheng Yin, Yufeng Luo, Tuanjie Wang, Bo Liu, Xiaoyun Chen
Journal: Toxicon
PubMed ID: 37543293
Doi: 10.1016/j.toxicon.2023.107234
Directed evolution of TetR for constructing sensitive and broad-spectrum tetracycline antibiotics whole-cell biosensor
Authors: Shunlan Li, Dongdong Chen, Ziqing Liu, Shipin Tao, Tianyi Zhang, Yiwen Chen, Lingzhi Bao, Jie Ma, Yuee Huang, Shengmin Xu, Lijun Wu, Shaopeng Chen
Journal: J Hazard Mater
PubMed ID: 37633019
Doi: 10.1016/j.jhazmat.2023.132311
Directed evolution rice genes with randomly multiplexed sgRNAs assembly of base editors
Authors: Ao Zhang, Tiaofeng Shan, Yan Sun, Zhipeng Chen, Jianjian Hu, Zhichao Hu, Ziheng Ming, Zhitao Zhu, Xue Li, Jun He, Shijia Liu, Ling Jiang, Xiaoou Dong, Yufeng Wu, Yanpeng Wang, Yuqiang Liu, Chao Li, Jianmin Wan
Journal: Plant Biotechnol J
PubMed ID: 37571976
Doi: 10.1111/pbi.14156
Identification of potential SLA-I-specific T-cell epitopes within the structural proteins of porcine deltacoronavirus
Authors: Yimin Wen, Rui Chen, Junpeng Yang, Enbo Yu, Weizhe Liu, Yijie Liao, Yiping Wen, Rui Wu, Qin Zhao, Senyan Du, Qigui Yan, Xinfeng Han, Sanjie Cao, Xiaobo Huang
Journal: Int J Biol Macromol
PubMed ID: 37579907
Doi: 10.1016/j.ijbiomac.2023.126327
Products & Services: Molecular Biology Reagents   
A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease
Authors: Zhi Zachary Geng, Sandeep Atla, Namir Shaabani, Veerabhadra Vulupala, Kai S Yang, Yugendar R Alugubelli, Kaustav Khatua, Peng-Hsun Chen, Jing Xiao, Lauren R Blankenship, Xinyu R Ma, Erol C Vatansever, Chia-Chuan D Cho, Yuying Ma, Robert Allen, Henry Ji, Shiqing Xu, Wenshe Ray Liu
Journal: J Med Chem
PubMed ID: 37561993
Doi: 10.1021/acs.jmedchem.3c00221
Products & Services: Custom DNA/RNA Oligos   
Structural basis for cross-group recognition of an influenza virus hemagglutinin antibody that targets postfusion stabilized epitope
Authors: Keisuke Tonouchi, Yu Adachi, Tateki Suzuki, Daisuke Kuroda, Ayae Nishiyama, Kohei Yumoto, Haruko Takeyama, Tadaki Suzuki, Takao Hashiguchi, Yoshimasa Takahashi
Journal: PLoS Pathog
PubMed ID: 37556494
Doi: 10.1371/journal.ppat.1011554
Products & Services: Peptide Synthesis   

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