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A conserved motif in the immune-subdominant RAP-1 related antigen of contains a B-cell epitope recognized by antibodies from protected cattle

Authors: Manuel J Rojas, Reginaldo G Bastos, Jinna Navas, Jacob M Laughery, Paul A Lacy, Carlos E Suarez

Journal: Front Immunol

PubMed ID: 38720894

Doi: 10.3389/fimmu.2024.1380660

Products & Services: Protein and Antibody Isolation

The impact of HBx protein on mitochondrial dynamics and associated signaling pathways strongly depends on the hepatitis B virus genotype

Authors: Anja Schollmeier, Michael Basic, Mirco Glitscher, Eberhard Hildt

Journal: J Virol

PubMed ID: 38629837

Doi: 10.1128/jvi.00424-24

Products & Services: Molecular Biology Reagents

Food-Grade Expression of Two Laccases in and Study on Their Enzymatic Degradation Characteristics for Mycotoxins

Authors: Zhen Sun, Yingxin You, Huidong Xu, Yang You, Wenjing He, Zhouping Wang, Aitao Li, Yu Xia

Journal: J Agric Food Chem

PubMed ID: 38600054

Doi: 10.1021/acs.jafc.4c00521

Products & Services: Gene Synthesis

Searching for new plastic-degrading enzymes from the plastisphere of alpine soils using a metagenomic mining approach

Authors: Beat Frey, Margherita Aiesi, Basil M Rast, Joel Rüthi, Jérôme Julmi, Beat Stierli, Weihong Qi, Ivano Brunner

Journal: PLoS ONE

PubMed ID: 38578779

Doi: 10.1371/journal.pone.0300503

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The Trimeric Autotransporter Adhesin SadA from spp as a Novel Bacterial Surface Display System

Authors: Shuli Sang, Wenge Song, Lu Lu, Qikun Ou, Yiyan Guan, Haoxia Tao, Yanchun Wang, Chunjie Liu

Journal: Vaccines (Basel)

PubMed ID: 38675781

Doi: 10.3390/vaccines12040399

Products & Services: Protein and Antibody Isolation

Plasmodium RNA triphosphatase validation as antimalarial target

Authors: Sonia Moliner-Cubel, Noemi Bahamontes-Rosa, Ane Rodriguez-Alejandre, Pamela M Nassau, Argyrides Argyrou, Anshu Bhardwaja, Rachel C Buxton, David Calvo-Vicente, Bernadette Mouzon, William McDowell, Alfonso Mendoza-Losana, Maria G Gomez-Lorenzo

Journal: Int J Parasitol Drugs Drug Resist

PubMed ID: 38810336

Doi: 10.1016/j.ijpddr.2024.100537

Products & Services: Molecular Biology Reagents

microRNA-2184 orchestrates Mauthner-cell axon regeneration in zebrafish via syt3 modulation

Authors: Xinghan Chen, Yueru Shen, Zheng Song, Xinliang Wang, Huaitong Yao, Yuan Cai, Zi-Ang Zhao, Bing Hu

Journal: J Genet Genomics

PubMed ID: 38582297

Doi: 10.1016/j.jgg.2024.03.016

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A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells

Authors: Hema Preethi Subas Satish, Sweta Iyer, Melissa X Shi, Agnes W Wong, Karla C Fischer, Ahmad Z Wardak, Daisy Lio, Jason M Brouwer, Rachel T Uren, Peter E Czabotar, Michelle S Miller, Ruth M Kluck

Journal: Cell Death Differ

PubMed ID: 38582955

Doi: 10.1038/s41418-024-01289-3

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The proteomic analysis uncovers the cellular responses to the African swine fever virus membrane proteins p54, p17, and pB117L

Authors: Yuhong Chen, Jianqiang Ni, Chuanbin Wang, Xinyan Zhai, Tingrong Luo, Yi-Ping Li, Youchuan Wei, Yuliang Liu

Journal: Microbes Infect

PubMed ID: 38697277

Doi: 10.1016/j.micinf.2024.105348

Products & Services: Molecular Biology Reagents

Interleukin-2 is required for NKp30-dependent NK cell cytotoxicity by preferentially regulating NKp30 expression

Authors: Nayoung Kim, Eunbi Yi, Eunbi Lee, Hyo Jin Park, Hun Sik Kim

Journal: Front Immunol

PubMed ID: 38698855

Doi: 10.3389/fimmu.2024.1388018

Products & Services: Molecular Biology Reagents

Knockdown of heat shock protein family D member 1 (HSPD1) in lung cancer cell altered secretome profile and cancer-associated fibroblast induction

Authors: Siripat Aluksanasuwan, Keerakarn Somsuan, Jatuporn Ngoenkam, Wararat Chiangjong, Artitaya Rongjumnong, Atthapan Morchang, Somchai Chutipongtanate, Sutatip Pongcharoen

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38663552

Doi: 10.1016/j.bbamcr.2024.119736

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Two mosquito salivary antigens demonstrate promise as biomarkers of recent exposure to infected mosquito bites

Authors: Sarah Lapidus, Morgan M Goheen, Mouhamad Sy, Awa B Deme, Ibrahima Mbaye Ndiaye, Younous Diedhiou, Amadou Moctar Mbaye, Kelly A Hagadorn, Seynabou Diouf Sene, Mariama Nicole Pouye, Laty Gaye Thiam, Aboubacar Ba, Noemi Guerra, Alassane Mbengue, Hamidah Raduwan, Inés Vigan-Womas, Sunil Parikh, Albert I Ko, Daouda Ndiaye, Erol Fikrig, Yu-Min Chuang, Amy K Bei

Journal: medrxiv

PubMed ID: 38712295

Doi: 10.1101/2024.04.20.24305430

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Amino Terminal Acetylation of HOXB13 Regulates the DNA Damage Response in Prostate Cancer

Authors: Duy T Nguyen, Urvashi Mahajan, Duminduni Hewa Angappulige, Aashna Doshi, Nupam P Mahajan, Kiran Mahajan

Journal: Cancers (Basel)

PubMed ID: 38730575

Doi: 10.3390/cancers16091622

Products & Services: Molecular Biology Reagents

Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity

Authors: Qiongqiong Zhou, Deshi Shi, Yan-Dong Tang, Longfeng Zhang, Boli Hu, Chunfu Zheng, Li Huang, Changjiang Weng

Journal: PLoS Pathog

PubMed ID: 38669242

Doi: 10.1371/journal.ppat.1012146

Products & Services: Protein and Antibody Isolation

Development of an isotope dilution mass spectrometry assay for the quantification of insulin based on signature peptide analysis

Authors: Shangying Ma, Rimei He, Tingting Jiang, Zhishang Hu, Zihong Ye, Wei Mi

Journal: Anal Bioanal Chem

PubMed ID: 38556594

Doi: 10.1007/s00216-024-05258-0

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Specificity of DNA ADP-Ribosylation Reversal by NADARs

Authors: Bara Cihlova, Yang Lu, Andreja Mikoč, Marion Schuller, Ivan Ahel

Journal: Toxins (Basel)

PubMed ID: 38787060

Doi: 10.3390/toxins16050208

Products & Services: Molecular Biology Reagents

Identification of a linear B-cell epitope on the "puff" loop of the Senecavirus A VP2 protein involved in receptor binding

Authors: Hanrong Zhou, Mingxia Sun, Shibo Su, Liang Meng, Wei Yang, Lan Yang, Xinqi Shi, Xin Li, Haiwei Wang, Hongwei Ma, Xuehui Cai, Yan-Dong Tang, Tongqing An, Fandan Meng

Journal: Front Microbiol

PubMed ID: 38716170

Doi: 10.3389/fmicb.2024.1387309

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LLPS of FXR proteins drives replication organelle clustering for β-coronaviral proliferation

Authors: Meng Li, Yali Hou, Yuzheng Zhou, Zhenni Yang, Hongyu Zhao, Tao Jian, Qianxi Yu, Fuxing Zeng, Xiaotian Liu, Zheng Zhang, Yan G Zhao

Journal: J Cell Biol

PubMed ID: 38587486

Doi: 10.1083/jcb.202309140

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The transcription factor BMI1 increases hypoxic signaling in oral cavity epithelia

Authors: Jorge Baquero, Xiao-Han Tang, Annalisa Ferrotta, Tuo Zhang, Krysta M DiKun, Lorraine J Gudas

Journal: Biochim Biophys Acta Mol Basis Dis

PubMed ID: 38599260

Doi: 10.1016/j.bbadis.2024.167161

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Specifically targeting antimicrobial peptides for inhibition of Candidatus Liberibacter asiaticus

Authors: Samavath Mallawarachchi, Haoqi Wang, Nirmitee Mulgaonkar, Sonia Irigoyen, Carmen Padilla, Kranthi Mandadi, James Borneman, Sandun Fernando

Journal: J Appl Microbiol

PubMed ID: 38509024

Doi: 10.1093/jambio/lxae061

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Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology

Authors: Keming Lin, Baijin Xia, Xuemei Wang, Xin He, Mo Zhou, Yingtong Lin, Yidan Qiao, Rong Li, Qier Chen, Yuzhuang Li, Jinzhu Feng, Tao Chen, Cancan Chen, Xinyu Li, Hui Zhang, Lijuan Lu, Bingfeng Liu, Xu Zhang

Journal: J Transl Med

PubMed ID: 38610029

Doi: 10.1186/s12967-024-05159-x

Products & Services: Protein Electrophoresis and Western

Combined sensory, volatilome and transcriptome analyses identify a limonene terpene synthase as a major contributor to the characteristic aroma of a Coffea arabica L specialty coffee

Authors: Lison Marie, Jean-Christophe Breitler, Pingdwende Kader Aziz Bamogo, Mélanie Bordeaux, Séverine Lacombe, Maëlle Rios, Marc Lebrun, Renaud Boulanger, Eveline Lefort, Sunao Nakamura, Yudai Motoyoshi, Delphine Mieulet, Claudine Campa, Laurent Legendre, Benoît Bertrand

Journal: BMC Plant Biol

PubMed ID: 38566027

Doi: 10.1186/s12870-024-04890-3

Products & Services: Molecular Biology Reagents

The gene "degrees of kevin bacon" (dokb) regulates a social network behaviour in Drosophila melanogaster

Authors: Rebecca Rooke, Joshua J Krupp, Amara Rasool, Mireille Golemiec, Megan Stewart, Jonathan Schneider, Joel D Levine

Journal: Nat Commun

PubMed ID: 38688961

Doi: 10.1038/s41467-024-47499-8

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Non-Invasive Delivery of Negatively Charged Nanobodies by Anodal Iontophoresis: When Electroosmosis Dominates Electromigration

Authors: Phedra Firdaws Sahraoui, Oscar Vadas, Yogeshvar N Kalia

Journal: Pharmaceutics

PubMed ID: 38675200

Doi: 10.3390/pharmaceutics16040539

Products & Services: Molecular Biology Reagents

iJAZ-based approach to engineer lepidopteran pest resistance in multiple crop species

Authors: Huijuan Mo, Huimin Chang, Ge Zhao, Guanjing Hu, Xiumei Luo, Xue Jia, Zhenlu Xu, Guangming Ren, Li Feng, Jonathan F Wendel, Xiaoya Chen, Maozhi Ren, Fuguang Li

Journal: Nat Plants

PubMed ID: 38684916

Doi: 10.1038/s41477-024-01682-3

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Blue light induced ferroptosis via STAT3/GPX4/SLC7A11/FTH1 in conjunctiva epithelium in vivo and in vitro

Authors: Qianjie Yang, Yutong Xia, Kuangqi Chen, Yinhao Wang, Dongjie Song, Jiru Zhu, Jianping Tong, Ye Shen

Journal: J Photochem Photobiol B

PubMed ID: 38663336

Doi: 10.1016/j.jphotobiol.2024.112908

Products & Services: Molecular Biology Reagents

Phage defence system CBASS is regulated by a prokaryotic E2 enzyme that imitates the ubiquitin pathway

Authors: Yan Yan, Jun Xiao, Fengtao Huang, Wei Xian, Bingbing Yu, Rui Cheng, Hui Wu, Xueling Lu, Xionglue Wang, Wenjing Huang, Jing Li, Greater Kayode Oyejobi, Carol V Robinson, Hao Wu, Di Wu, Xiaoyun Liu, Longfei Wang, Bin Zhu

Journal: Nat Microbiol

PubMed ID: 38649411

Doi: 10.1038/s41564-024-01684-z

Products & Services: Codon Optimization

Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing

Authors: Qiubing Chen, Xuebin Wang, Yizhou Zhang, Ming Tian, Junyi Duan, Ying Zhang, Hao Yin

Journal: NSR

Doi: 10.1093/nsr/nwae135

Products & Services: Gene Synthesis

Expanding the druggable zinc-finger proteome defines properties of drug-induced degradation

Authors: Miko aj S abicki; Jiho Park; Rados aw P. Nowak; Shourya S. Roy Burman; Jesse Pellman; Charles Zou; Hlib Razumkov; Jeannie Carreiro; Simran Rastogi; Anna Goldstein; Marek M. Nagiec; Katherine A. Donovan; Jianwei Che; Moritz Hunkeler; Qixiang Geng; Chi-Lin Hsu; Megha Lakshminarayan; Chelsea Shu; Rebecca L. Zon; Zuzanna Kozicka; Paul M.C. Park; Jonathan M. Tsai; Hojong Yoon; Lyn H. Jones; Adam S. Sperling; Nathanael S. Gray; Eric S. Fischer; Benjamin L. Ebert

Journal: Molecular Cell

PubMed ID: 40845806

Doi: 10.1016/j.molcel.2025.07.019

Sequential release of interacting proteins and Ub-modifying enzymes by disulfide heterotypic ubiquitin reagents

Authors: Hongyi Cai, Xiangwei Wu, Junxiong Mao, Zebin Tong, Dingfei Yan, Yicheng Weng, Qingyun Zheng

Journal: Bioorganic Chemistry

PubMed ID: 38387394

Doi: 10.1016/j.bioorg.2024.107186

Products & Services: Protein and Antibody Isolation

Akkermansia muciniphila exoglycosidases target extended blood group antigens to generate ABO-universal blood

Authors: Mathias Jensen, Linn Stenfelt, Jennifer Ricci Hagman, Michael Jakob Pichler, Julia Weikum, Tine Sofie Nielsen, Annika Hult, Jens Preben Morth, Martin L Olsson, Maher Abou Hachem

Journal: Nat Microbiol

PubMed ID: 38684911

Doi: 10.1038/s41564-024-01663-4

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Fluctuation of flavor quality in roasted duck: The consequences of raw duck preform's repetitive freeze-thawing

Authors: Ziwu Gao, Dequan Zhang, Ruiyun Wu, Jinhua He, Jiale Ma, Xiangxiang Sun, Minghui Gu, Zhenyu Wang

Journal: Food Res Int

PubMed ID: 38763675

Doi: 10.1016/j.foodres.2024.114424

Products & Services: Protein and Antibody Isolation

Systemic Effects of a Phage Cocktail on Healthy Weaned Piglets

Authors: Yankun Liu, Yan Lin, Weiyun Zhu

Journal: Biology (Basel)

PubMed ID: 38666883

Doi: 10.3390/biology13040271

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Expanding the Potential of Neoantigen Vaccines: Harnessing Bacille Calmette-Guérin Cell-Wall-Based Nanoscale Adjuvants for Enhanced Cancer Immunotherapy

Authors: Kangkang Liu, Jing Peng, Yunfei Guo, Yiming Li, Xiang Qi, Dengyi Duan, Taipeng Li, Jianmin Li, Yuanjie Niu, Gang Han, Yang Zhao

Journal: ACS Nano

PubMed ID: 38680054

Doi: 10.1021/acsnano.4c01691

Products & Services: Protein and Antibody Isolation

Visualization of the Association of Dimeric Protein Complexes on Specific Enhancers in the Salivary Gland Nuclei of Larva

Authors: Solène Vanderperre, Samir Merabet

Journal: Cells

PubMed ID: 38607052

Doi: 10.3390/cells13070613

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Dynamically stiffening biomaterials reveal age- and sex-specific differences in pulmonary arterial adventitial fibroblast activation

Authors: Mikala C Mueller, Yanmei Du, Lori A Walker, Chelsea M Magin

Journal: Matrix Biol Plus

PubMed ID: 38699486

Doi: 10.1016/j.mbplus.2024.100145

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The molecular immune modulator adenosine deaminase-1 enhances HIV specific humoral and cellular responses to a native-like HIV envelope trimer DNA vaccine

Authors: Michele A Kutzler, Gina Cusimano, David Joyner, Emily Konopka, Roshell Muir, Philip Barnette, Melanie Guderian, Iván Del Moral-Sánchez, Ronald Derking, Tom Bijl, Jonne Snitselaar, Photis Rotsides, Kyra Woloszczuk, Matthew Bell, Gabriela Canziani, Irwin Chaiken, Ann Hessell, Yannic Bartsch, Rogier Sanders, Elias Haddad

Journal: Res Sq

PubMed ID: 38746176

Doi: 10.21203/rs.3.rs-4139764/v1

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The use of Bacillus subtilis as a cost-effective expression system for production of Cholera Toxin B fused factor VIII epitope regions applicable for inducing oral immune tolerance

Authors: Vijay Elakkya Vijayakumar, Mookambeswaran A Vijayalakshmi, Sebastien Lacroix-Desmazes, Krishnan Venkataraman

Journal: Folia Microbiol (Praha)

PubMed ID: 38683262

Doi: 10.1007/s12223-024-01166-z

Products & Services: Molecular Biology Reagents

Mitochondria-Selective Dicationic Small-Molecule Ligand Targeting G-Quadruplex Structures for Human Colorectal Cancer Therapy

Authors: Bo-Xin Zheng, Wei Long, Wende Zheng, Yaoxun Zeng, Xiao-Chun Guo, Ka-Hin Chan, Meng-Ting She, Alan Siu-Lun Leung, Yu-Jing Lu, Wing-Leung Wong

Journal: J Med Chem

PubMed ID: 38624086

Doi: 10.1021/acs.jmedchem.3c02240

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Developing a Novel Enzalutamide-Resistant Prostate Cancer Model via AR F877L Mutation in LNCaP Cells

Authors: Ruifeng Wang, Shuhua Ma, Nengwei Xu, Yumiao Gan, Pengya Li, Jingying Zhang, Zhixiang Zhang, Qingyang Gu, Jian Xiang

Journal: Curr Protoc

PubMed ID: 38652202

Doi: 10.1002/cpz1.1033

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A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers

Authors: Dan-Dan Zhou, Xiao-Tian Zhai, Lan-Wen Zhang, Zi-Hui Xie, Ying Wang, Yong-Su Zhen, Rui-Juan Gao, Qing-Fang Miao

Journal: NPJ Precis Oncol

PubMed ID: 38654141

Doi: 10.1038/s41698-024-00584-z

Products & Services: Protein and Antibody Isolation

Combination of a TGF-β ligand trap (RAP-GRL) and TMPRSS6-ASO is superior for correcting β-thalassemia

Authors: Amaliris Guerra, Nolan Hamilton, Ariel Rivera, Perry Demsko, Shuling Guo, Stefano Rivella

Journal: Am J Hematol

PubMed ID: 38659383

Doi: 10.1002/ajh.27332

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Hymenopteran-specific TRPA channel from the Texas leaf cutter ant (Atta texana) is heat and cold activated and expression correlates with environmental temperature

Authors: Julia M York, Timothy N Taylor, Sarah LaPotin, Ying Lu, Ulrich Mueller

Journal: Insect Sci

PubMed ID: 38605428

Doi: 10.1111/1744-7917.13364

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Cellugyrin (synaptogyrin-2) dependent pathways are used by bacterial cytolethal distending toxin and SARS-CoV-2 virus to gain cell entry

Authors: Kathleen Boesze-Battaglia, Gary H Cohen, Paul F Bates, Lisa M Walker, Ali Zekavat, Bruce J Shenker

Journal: Front Cell Infect Microbiol

PubMed ID: 38698905

Doi: 10.3389/fcimb.2024.1334224

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Interplay of the Tfb1 pleckstrin homology domain with Rad2 and Rad4 in transcription coupled and global genomic nucleotide excision repair

Authors: Wenzhi Gong, Hannah Holmberg, Cheng Lu, Michelle Huang, Shisheng Li

Journal: Nucleic Acids Res

PubMed ID: 38634797

Doi: 10.1093/nar/gkae286

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A DNA circuit that records molecular events

Authors: Mingzhi Zhang, Colin Yancey, Chao Zhang, Junyan Wang, Qian Ma, Linlin Yang, Rebecca Schulman, Da Han, Weihong Tan

Journal: SCIENCE ADVANCES

PubMed ID: 38578999

Doi: 10.1126/sciadv.adn3329

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ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Authors: Guy J Pearson, Harriet V Mears, Malgorzata Broncel, Ambrosius P Snijders, David L V Bauer, Jeremy G Carlton

Journal: SCIENCE ADVANCES

PubMed ID: 38569033

Doi: 10.1126/sciadv.adl5012

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Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening

Authors: Xing Li, Shiyu Sun, Wansong Zhang, Ziwei Liang, Yitong Fang, Tianhu Sun, Yong Wan, Xingcong Ma, Shuqun Zhang, Yang Xu, Ruilin Tian

Journal: Experimental & Clinical Cancer Research

PubMed ID: 38561797

Doi: 10.1186/s13046-024-03027-6

Products & Services: Recombinant Proteins

Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning

Authors: Gorka Lasso; Michael Grodus; Estefania Valencia; Veronica DeJesus; Eliza Liang; Isabel Delwel; Rob H. Bortz; Dmitry Lupyan; Hanna Y. Ehrlich; Adrian A. Castellanos; Andrea Gazzo; Heather L. Wells; Supaporn Wacharapluesadee; Alexandre Tremeau-Bravard; Janine F.R. Seetahal; Tom Hughes; Jimmy Lee; Mei-Ho Lee; Anna R. Sjodin; Marike Geldenhuys; Marinda Mortlock; Isamara Navarrete-Macias; Kirsten Gilardi; Michael R. Willig; Alessandra F.D. Nava; Elisabeth H. Loh; Makda Asrat; Tierra Smiley-Evans; Walter S. Magesa; Sijali Zikankuba; David Wolking; Gerardo Suz n; Rafael Ojeda-Flores; Christine V.F. Carrington; Ariful Islam; Jonathan H. Epstein; Wanda Markotter; Christine K. Johnson; Tracey Goldstein; Barbara A. Han; Jonna A.K. Mazet; Rohit K. Jangra; Kartik Chandran; Simon J. Anthony

Journal: Cell Host & Microbe

PubMed ID: 39818205

Doi: 10.1016/j.chom.2024.12.016

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Virtual screening and evaluation of bioactive peptides from Haliotis discus hannai as potential HMGCR inhibitors for hyperlipidemia treatment

Authors: Kun Qiao; Lina Liu; Yihui Chen; Qiongmei Huang; Bei Chen; Jingna Wu; Wenmei Huang; Zhiyu Liu

Journal: Frontiers in nutrition

PubMed ID: 39811675

Doi: 10.3389/fnut.2024.1525768

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