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Characterization of antibodies targeting severe fever with thrombocytopenia syndrome virus glycoprotein Gc

Authors: Kaori Sano, Miyuki Kimura, Akiko Sataka, Hideki Hasegawa, Hideki Tani, Tadaki Suzuki

Journal: Arch Virol

PubMed ID: 38308735

Doi: 10.1007/s00705-024-05968-x

Products & Services: Protein and Antibody Isolation

A Pseudovirus-Based Neutralization Assay for SARS-CoV-2 Variants: A Rapid, Cost-Effective, BSL-2-Based High-Throughput Assay Useful for Vaccine Immunogenicity Evaluation

Authors: Zhaohui Cai, Raj Kalkeri, Mingzhu Zhu, Shane Cloney-Clark, Benjamin Haner, Mi Wang, Bahar Osman, Dominic Dent, Sheau-Line Feng, Zach Longacre, Greg Glenn, Joyce S Plested

Journal: Microorganisms

PubMed ID: 38543552

Doi: 10.3390/microorganisms12030501

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Primary vulvar adenocarcinoma of intestinal type: Report of two cases showing molecular similarity with colorectal adenocarcinoma

Authors: Claudia Mateoiu, Andrea Palicelli, Thais Maloberti, Dario De Biase, Antonio De Leo, Magnus Lindh, Katja Stenström Bohlin, Simona Stolnicu

Journal: Pathol Res Pract

PubMed ID: 38340583

Doi: 10.1016/j.prp.2024.155181

Products & Services: Molecular Biology Reagents

Lymph Node-Targeted Vaccine Boosting of TCR T-cell Therapy Enhances Antitumor Function and Eradicates Solid Tumors

Authors: Dylan J Drakes, Abdulraouf M Abbas, Jacqueline Shields, Martin P Steinbuck, Aniela Jakubowski, Lochana M Seenappa, Christopher M Haqq, Peter C DeMuth

Journal: Cancer Immunol Res

PubMed ID: 38270373

Doi: 10.1158/2326-6066.CIR-22-0978

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Chimeric nanobody-decorated liposomes by self-assembly

Authors: Md Mofizur Rahman, Jing Wang, Guosheng Wang, Zhipeng Su, Yizeng Li, Yundi Chen, Jinguo Meng, Yao Yao, Lefei Wang, Stephan Wilkens, Jifu Tan, Juntao Luo, Tao Zhang, Chuandong Zhu, Sung Hyun Cho, Lixue Wang, Luke P Lee, Yuan Wan

Journal: Nat Nanotechnol

PubMed ID: 38374413

Doi: 10.1038/s41565-024-01620-6

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Impact of sex on humoral immunity with live influenza B virus vaccines in mice

Authors: Stivalis Cardenas-Garcia, C Joaquín Cáceres, Aarti Jain, Ginger Geiger, Jong-Suk Mo, L Claire Gay, Brittany Seibert, Algimantas Jasinskas, Rie Nakajima, Daniela S Rajao, D Huw Davies, Daniel R Perez

Journal: npj Vaccines

PubMed ID: 38409236

Doi: 10.1038/s41541-024-00827-x

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Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD

Authors: Basila Moochickal Assainar, Kaushik Ragunathan, Ryan D Baldridge

Journal: Nat Commun

PubMed ID: 38351109

Doi: 10.1038/s41467-024-45541-3

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Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes

Authors: Luis López, Kelly Lozano, John Cruz, Krystal Flores, Lauren Fernández-Vega, Lisandro Cunci

Journal: Neuropeptides

PubMed ID: 38335798

Doi: 10.1016/j.npep.2024.102413

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Efficient preparation of high-purity and intact mesenchymal stem cell-derived extracellular vesicles

Authors: Fangfang Ni, Qingfu Zhu, Hengrui Li, Fei Liu, Hao Chen

Journal: Anal Bioanal Chem

PubMed ID: 38355844

Doi: 10.1007/s00216-024-05193-0

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miR-193b-5p promotes GCRV replication by inhibiting autophagy via targeting deptor in grass carp (Ctenopharyngodon idellus)

Authors: Hongyan Yu, Zheyan Chen, Qiaozhen Yu, Yubang Shen, Lang Gui, Xiaoyan Xu, Jiale Li

Journal: Fish Shellfish Immunol

PubMed ID: 38365163

Doi: 10.1016/j.fsi.2024.109453

Products & Services: Protein and Antibody Isolation

Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane

Authors: Rebika Shrestha, Timothy S Carpenter, Que N Van, Constance Agamasu, Marco Tonelli, Fikret Aydin, De Chen, Gulcin Gulten, James N Glosli, Cesar A López, Tomas Oppelstrup, Chris Neale, Sandrasegaram Gnanakaran, William K Gillette, Helgi I Ingólfsson, Felice C Lightstone, Andrew G Stephen, Frederick H Streitz, Dwight V Nissley, Thomas J Turbyville

Journal: Commun Biol

PubMed ID: 38418613

Doi: 10.1038/s42003-024-05916-0

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Identification and characterization of the low molecular mass ferredoxins involved in central metabolism in Heliomicrobium modesticaldum

Authors: Karim A Walters, Kevin E Redding, John H Golbeck

Journal: Photosynth Res

PubMed ID: 38306001

Doi: 10.1007/s11120-023-01069-z

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Poly-γ-glutamylation of biomolecules

Authors: Ghader Bashiri, Esther M M Bulloch, William R Bramley, Madison Davidson, Stephanie M Stuteley, Paul G Young, Paul W R Harris, Muhammad S H Naqvi, Martin J Middleditch, Michael Schmitz, Wei-Chen Chang, Edward N Baker, Christopher J Squire

Journal: Nat Commun

PubMed ID: 38346985

Doi: 10.1038/s41467-024-45632-1

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Cross-Phosphorylation between AgrC Histidine Kinase and the Noncognate Response Regulator Lmo1172 in under Benzalkonium Chloride Stress

Authors: Tao Yu, Xiaojie Jiang, Xiaobo Xu, Ping Xu, Shuxing Qiu, Junlei Yin, David P Hamilton, Xiaobing Jiang

Journal: Microorganisms

PubMed ID: 38399796

Doi: 10.3390/microorganisms12020392

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Enhancing sensitivity of qPCR assays targeting Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae by using a mutant Taq DNA polymerase

Authors: Selin Nar Otgun, Canan Zohre Ketre Kolukirik, Nuriye Unal Sahin, Mustafa Kolukirik, Gozde Girgin Ozgumus, Meral Turan, Mert Elmas, Selcuk Kilic

Journal: J Microbiol Methods

PubMed ID: 38360298

Doi: 10.1016/j.mimet.2024.106899

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Nanobody-Mediated Dualsteric Engagement of the Angiotensin Receptor Broadens Biased Ligand Pharmacology

Authors: Nayara Braga Emidio , Brandi M Small , Amanda R Keller , Ross W Cheloha , Laura M Wingler

Journal: Mol Pharmacol

PubMed ID: 38164609

Doi: 10.1124/molpharm.123.000797

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Ribosomal collision is not a prerequisite for ZNF598-mediated ribosome ubiquitination and disassembly of ribosomal complexes by ASCC

Authors: Anna Miścicka, Alexander G Bulakhov, Kazushige Kuroha, Alexandra Zinoviev, Christopher U T Hellen, Tatyana V Pestova

Journal: Nucleic Acids Res

PubMed ID: 38366554

Doi: 10.1093/nar/gkae087

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GDI2 deletion alleviates neurodegeneration and memory loss in the 5xFAD mice model of Alzheimer's disease

Authors: Meitian Wang, Xiuqing He, Jie Li, Daobin Han, Pan You, Hui Yu, Luwen Wang, Bo Su

Journal: Biochim Biophys Acta Mol Basis Dis

PubMed ID: 38382624

Doi: 10.1016/j.bbadis.2024.167093

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Integrating network pharmacology and experimental models to identify notoginsenoside R1 ameliorates atherosclerosis by inhibiting macrophage NLRP3 inflammasome activation

Authors: Jingyue Yu, Jinyu Hu, Margaret Baldini, Huan Lei, Lei Li, Shanshan Luo, Jielian Wu, Xupin Liu, Dan Shan, Yanfei Xie, Haihong Fang, Jun Yu

Journal: J Nat Med

PubMed ID: 38409483

Doi: 10.1007/s11418-023-01776-w

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Therapeutic potential of exosome derived from hepatocyte growth factor-overexpressing adipose mesenchymal stem cells in TGFβ1-stimulated hepatic stellate cells

Authors: Jin Wang, Weikang Ye, Ming Jiang, Yinong Zhou, Jie Zheng

Journal: Cytotechnology

PubMed ID: 38495297

Doi: 10.1007/s10616-023-00611-0

Products & Services: Molecular Biology Reagents

Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel Na18 with a Unique Mechanism of Action

Authors: John M Gilchrist, Nien-Du Yang, Victoria Jiang, Bryan D Moyer

Journal: Mol Pharmacol

PubMed ID: 38195157

Doi: 10.1124/molpharm.123.000789

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Inhibition of AMPK activation in sensu stricto limits the parasite's glucose metabolism and survival

Authors: Mingzhi Yan, Hui Liu, Yansen Su, Xiaojuan Bi, Ning Yang, Renyong Lin, Guodong Lü

Journal: Antimicrob Agents Chemother

PubMed ID: 38349157

Doi: 10.1128/aac.01202-23

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The ETI-dependent receptor-like kinase 1 positively regulates effector-triggered immunity by stabilizing NLR-required for cell death 4 in Nicotiana benthamiana

Authors: Yujing Sun, Fan Liu, Mengzhu Zeng, Xinjie Zhang, Ying Cui, Zhaodan Chen, Lei Wang, Yuanpeng Xu, Jinbin Wu, Shengya Guo, Xian Dong, Suomeng Dong, Yan Wang, Yuanchao Wang

Journal: New Phytol

PubMed ID: 38362937

Doi: 10.1111/nph.19596

Products & Services: DNA Sequencing

Membrane-Associated Ubiquitin Ligase RING Finger Protein 152 Orchestrates Melanogenesis via Tyrosinase Ubiquitination

Authors: Ryota Ueda, Rina Hashimoto, Yuki Fujii, José C J M D S Menezes, Hirotaka Takahashi, Hiroyuki Takeda, Tatsuya Sawasaki, Tomonori Motokawa, Kenzo Tokunaga, Hideaki Fujita

Journal: Membranes (Basel)

PubMed ID: 38392670

Doi: 10.3390/membranes14020043

Molecular mechanism of human ISG20L2 for the ITS1 clea vag e in the processing of 18S precursor ribosomal RNA

Authors: Yinliang Ma, Jiaxu Wang, Xingyi He, Yuhang Liu, Shuo Zhen, Lina An, Qian Yang, Fumin Niu, Hong Wang, Boran An, Xinyue Tai, Zhenzhen Yan, Chen Wu, Xiaoyun Yang, Xiuhua Liu

Journal: Nucleic Acids Res

PubMed ID: 38153123

Doi: 10.1093/nar/gkad1210

Products & Services: Gene Synthesis

Newcastle disease virus regulates its replication by instigating oxidative stress-driven Sirtuin 7 production

Authors: Kamal Shokeen, Sachin Kumar

Journal: J Gen Virol

PubMed ID: 38376490

Doi: 10.1099/jgv.0.001961

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Filamin A Is a Prognostic Serum Biomarker for Differentiating Benign Prostatic Hyperplasia from Prostate Cancer in Caucasian and African American Men

Authors: Nischal Mahaveer Chand, Poornima K Tekumalla, Matt T Rosenberg, Albert Dobi, Amina Ali, Gregory M Miller, Juan J Aristizabal-Henao, Elder Granger, Stephen J Freedland, Mark D Kellogg, Shiv Srivastava, David G McLeod, Niven R Narain, Michael A Kiebish

Journal: Cancers (Basel)

PubMed ID: 38398103

Doi: 10.3390/cancers16040712

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Safety and immunogenicity of CoronaVac in healthy adults: A prospective observational multicenter real-world study in Henan Province, China

Authors: Benchen Rao, Ling Wang, Mengzhao Yang, Hong Luo, Junyi Sun, Shanshuo Liu, Haiyu Wang, Xuemei Wang, Lei Li, Chengyu Yuan, Zujiang Yu, Zhigang Ren

Journal: Virulence

PubMed ID: 38326274

Doi: 10.1080/21505594.2024.2310450

Products & Services: Molecular Biology Reagents

DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α

Authors: Aidi Gao, Mingxia Zhang, Shuang Qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao

Journal: Cell Death Dis

PubMed ID: 38402183

Doi: 10.1038/s41419-024-06552-6

Products & Services: Protein and Antibody Isolation

SARS-CoV-2 Membrane protein regulates the function of Spike by inhibiting its plasma membrane localization and enzymatic activity of Furin

Authors: Qi Xiang, Jie Wu, Yuzheng Zhou, Linhao Li, Miao Tian, Guobao Li, Zheng Zhang, Yang Fu

Journal: Microbiol Res

PubMed ID: 38430890

Doi: 10.1016/j.micres.2024.127659

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Targeting deoxynivalenol for degradation by a chimeric manganese peroxidase/glutathione system

Authors: Xiaoyun Su, Shuai Wang, Xiaolu Wang, Wangli Ji, Honglian Zhang, Tao Tu, Nina Hakulinen, Huiying Luo, Wei Zhang, Huoqing Huang

Journal: Ecotoxicol Environ Saf

PubMed ID: 38394761

Doi: 10.1016/j.ecoenv.2024.116130

Maternal Phlorizin Intake Protects Offspring from Maternal Obesity-Induced Metabolic Disorders in Mice via Targeting Gut Microbiota to Activate the SCFA-GPR43 Pathway

Authors: Xueran Mei, Yi Li, Xiaoyu Zhang, Xiwen Zhai, Yi Yang, Zhengjuan Li, Liping Li

Journal: J Agric Food Chem

PubMed ID: 38349207

Doi: 10.1021/acs.jafc.3c06370

Products & Services: Protein and Antibody Isolation

Structure of the p53 degradation complex from HPV16

Authors: John C K Wang, Hannah T Baddock, Amirhossein Mafi, Ian T Foe, Matthew Bratkowski, Ting-Yu Lin, Zena D Jensvold, Magdalena Preciado López, David Stokoe, Dan Eaton, Qi Hao, Aaron H Nile

Journal: Nat Commun

PubMed ID: 38418456

Doi: 10.1038/s41467-024-45920-w

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Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia

Authors: Wonjae Sung, Min-Young Noh, Minyeop Nahm, Yong Sung Kim, Chang-Seok Ki, Young-Eun Kim, Hee-Jin Kim, Seung Hyun Kim

Journal: J Neuroinflammation

PubMed ID: 38347588

Doi: 10.1186/s12974-024-03039-1

Products & Services: Gene Synthesis

Proteomic analysis of milk fat globule membrane proteins in mature human milk of women with and without gestational diabetes mellitus

Authors: Dan Yao, Cai Shen, Jingwen Yu, Jiayue Tang, Hong Zhang, Xuebing Xu, Maolin Tu, Ling-Zhi Cheong

Journal: Food Chem

PubMed ID: 38354646

Doi: 10.1016/j.foodchem.2024.138691

Products & Services: Molecular Biology Reagents

Development of an indirect ELISA for the serodiagnosis of canine infection by Onchocerca lupi

Authors: Maria Stefania Latrofa, Viviane Noll Louzada-Flores, Carla Maia, Maureen A Kelly, Guilherme G Verocai, Cinzia Cantacessi, Domenico Otranto

Journal: Sci Rep

PubMed ID: 38336818

Doi: 10.1038/s41598-024-53759-w

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Identification of Candidate Expansin Genes Associated with Seed Weight in Pomegranate ( L)

Authors: Chunyan Liu, Haoyu Zhao, Jiyu Li, Zhen Cao, Bo Deng, Xin Liu, Gaihua Qin

Journal: Genes (Basel)

PubMed ID: 38397202

Doi: 10.3390/genes15020212

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Ultrasound-mediated gene delivery specifically targets liver sinusoidal endothelial cells for sustained FVIII expression in hemophilia A mice

Authors: Savannah M Lawton, Megan A Manson, Meng-Ni Fan, Ting-Yen Chao, Chun-Yu Chen, Peter Kim, Carley Campbell, Xiaohe Cai, Amber Vander Kooi, Carol H Miao

Journal: Mol Ther

PubMed ID: 38341614

Doi: 10.1016/j.ymthe.2024.02.010

Products & Services: Protein Electrophoresis and Western

Characterization of cleavage patterns and assembly of N-terminally modified GII6 norovirus VP1 proteins

Authors: Jie Ma, Jinjin Liu, Yuqi Huo

Journal: Arch Virol

PubMed ID: 38386207

Doi: 10.1007/s00705-024-05973-0

Products & Services: Protein Electrophoresis and Western

A BET inhibitor, NHWD-870, can downregulate dendritic cells maturation via the IRF7-mediated signaling pathway to ameliorate imiquimod-induced psoriasis-like murine skin inflammation

Authors: Liping Jin, Liang Dong, Shiyao Pei, Xiang Chen, Yehong Kuang, Wangqing Chen, Wu Zhu, Mingzhu Yin

Journal: Eur J Pharmacol

PubMed ID: 38311277

Doi: 10.1016/j.ejphar.2024.176382

Products & Services: Recombinant Proteins

Unravelling the reason for different binding behaviors exhibited by antibody aggregates towards preparative and analytical Protein A columns

Authors: Wanyuan Dong, Mengying Tian, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 38423157

Doi: 10.1016/j.pep.2024.106449

Products & Services: Protein Electrophoresis and Western

Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors

Authors: Kiara N Berríos, Aleksia Barka, Jasleen Gill, Juan C Serrano, Peter F Bailer, Jared B Parker, Niklaus H Evitt, Kiran S Gajula, Junwei Shi, Rahul M Kohli

Journal: Nucleic Acids Res

PubMed ID: 38261989

Doi: 10.1093/nar/gkae024

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Erdr1 Drives Macrophage Programming via Dynamic Interplay with YAP1 and Mid1

Authors:

Journal: Immunohorizons

PubMed ID: 38392560

Doi: 10.4049/immunohorizons.2400004

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The Role of Hyaluronan/Receptor for Hyaluronan-Mediated Motility Interactions in the Modulation of Macrophage Polarization and Cartilage Repair

Authors: Emilia Bianchini, Yun Jin Ashley Sin, You Jin Lee, Charles Lin, Utkarsh Anil, Cassie Hamill, Mary K Cowman, Thorsten Kirsch

Journal: Am J Pathol

PubMed ID: 38403161

Doi: 10.1016/j.ajpath.2024.01.020

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SOX9 Induces Orbital Fibroblast Activation in Thyroid Eye Disease Via MAPK/ERK1/2 Pathway

Authors: Min Zhou, Bingying Lin, Pengsen Wu, Yu Ke, Siyu Huang, Fan Zhang, Xiangqing Hei, Zhen Mao, Xingyi Li, Pengxia Wan, Tingting Chen, Huasheng Yang, Danping Huang

Journal: Invest Ophthalmol Vis Sci

PubMed ID: 38345552

Doi: 10.1167/iovs.65.2.25

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Ultrasound Imaging of Tumor Vascular CD93 with MMRN2 Modified Microbubbles for Immune Microenvironment Prediction

Authors: Dingyi Wang, Changyang Xing, Yuan Liang, Chen Wang, Ping Zhao, Xiao Liang, Qiuyang Li, Lijun Yuan

Journal: Adv Mater

PubMed ID: 38270289

Doi: 10.1002/adma.202310421

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ATP10A deficiency results in male-specific infertility in mice

Authors: Adriana C Norris, Eugenia M Yazlovitskaya, Tzushan Sharon Yang, Alex Mansueto, John M Stafford, Todd R Graham

Journal: Front Cell Dev Biol

PubMed ID: 38415274

Doi: 10.3389/fcell.2024.1310593

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A sustainable strategy for biosynthesis of Rebaudioside D using a novel glycosyltransferase of Solanum tuberosum

Authors: Siyuan Ma, Yuanyuan Ma

Journal: Biotechnol J

PubMed ID: 38403450

Doi: 10.1002/biot.202300628

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Inhibition of NS2B-NS3 protease from all four serotypes of dengue virus by punicalagin, punicalin and ellagic acid identified from

Authors: Fouzia Ismat, Anam Tariq, Aqsa Shaheen, Raheem Ullah, Kayode Raheem, Muhammad Muddassar, Sadia Mahboob, Wasim Abbas, Mazhar Iqbal, Moazur Rahman

Journal: J Biomol Struct Dyn

PubMed ID: 38373021

Doi: 10.1080/07391102.2024.2314258

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Preorganized cyclic modules facilitate the self-assembly of protein nanostructures

Authors: Jaka Snoj, Fabio Lapenta, Roman Jerala

Journal: Chem Sci

PubMed ID: 38455016

Doi: 10.1039/d3sc06658d

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