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Structure and function analysis of a type III preQ1-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence
Authors: Griffin M Schroeder , Daniil Kiliushik , Jermaine L Jenkins , Joseph E Wedekind
Journal: J Biol Chem .
PubMed ID: 37660906
Doi: 10.1016/j.jbc.2023.105208
Products & Services: Mutagenesis Services   
A novel C-type lectin (SpccCTL) suppresses MCRV replication by binding viral protein and regulating antiviral peptides in Scylla paramamosain
Authors: Qing-Feng Yang, Shouhu Li, Guang-Peng Feng, Chuang Qin, Xiu-Wen Min, Wen-Hong Fang, Yue Wu, Jin Zhou, Xin-Cang Li
Journal: Fish Shellfish Immunol
PubMed ID: 37827249
Doi: 10.1016/j.fsi.2023.109143
CRISPR/Cas9 System-Mediated Multi-copy Expression of an Alkaline Serine Protease in for the Production of XOD-Inhibitory Peptides
Authors: Shounan Wang, Yibin Xue, Peng Zhang, Qiaojuan Yan, Yanxiao Li, Zhengqiang Jiang
Journal: J Agric Food Chem
PubMed ID: 37807677
Doi: 10.1021/acs.jafc.3c04138
Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies
Authors: Matthias Schmidt, Namil Lee, Chunjun Zhan, Jacob B Roberts, Alberto A Nava, Leah S Keiser, Aaron A Vilchez, Yan Chen, Christopher J Petzold, Robert W Haushalter, Lars M Blank, Jay D Keasling
Journal: ACS Synth Biol
PubMed ID: 37851920
Doi: 10.1021/acssynbio.3c00367
Cornelia de Lange Syndrome mutations in SMC1A cause cohesion defects in yeast
Authors: Jingrong Chen, Erin N Floyd, Dean S Dawson, Susannah Rankin
Journal: Genetics
PubMed ID: 37650609
Doi: 10.1093/genetics/iyad159
The CD4+ T cell repertoire specific for citrullinated peptides shows evidence of immune tolerance
Authors: Matthew K McElwee, Thamotharampillai Dileepan, Shawn A Mahmud, Marc K Jenkins
Journal: J Exp Med
PubMed ID: 37831103
Doi: 10.1084/jem.20230209
Products & Services: Peptide Synthesis   
Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform
Authors: Alexander Ernst, Indre Piragyte, Ayisha Marwa Mp, Ngoc Dung Le, Denis Grandgirard, Stephen L Leib, Andrew Oates, Nadia Mercader
Journal: Sci Rep
PubMed ID: 37813860
Doi: 10.1038/s41598-023-43911-3
Products & Services: Molecular Biology Reagents   
Allele-dependent expression and functionality of lipid enzyme PDAT affects diatom carbon storage and growth
Authors: Yufang Pan, Wanting Zhang, Xiaofei Wang, Juliette Jouhet, Eric Maréchal, Jin Liu, Xiao-Qin Xia, Hanhua Hu
Journal: Plant Physiol
PubMed ID: 37930282
Doi: 10.1093/plphys/kiad581
Products & Services: Monoclonal Antibody Services   
Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells
Authors: Paalini Sathiyaseelan, Suganthi Chittaranjan, Steve E Kalloger, Jennifer Chan, Nancy E Go, Mario A Jardon, Cally J Ho, Theodore Hui, Jing Xu, Christine Chow, Dongxia Gao, Fraser D Johnson, William W Lockwood, Gregg B Morin, Daniel J Renouf, David F Schaeffer, Sharon M Gorski
Journal: J Cell Sci
PubMed ID: 37701987
Doi: 10.1242/jcs.260644
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The Exocyst Subunit CsExo70B Promotes Both Fruit Length and Disease Resistance via Regulating Receptor Kinase Abundance at Plasma Membrane in Cucumber
Authors: Liu Liu , Jiacai Chen , Chaoheng Gu , Shaoyun Wang , Yufan Xue , Zhongyi Wang , Lijie Han , Weiyuan Song , Xiaofeng Liu , Jiahao Zhang , Min Li , Chuang Li , Liming Wang , Xiaolan Zhang , Zhaoyang Zhou
Journal: Plant Biotechnol J .
PubMed ID: 37795910
Doi: 10.1111/pbi.14189
Products & Services: Peptide Synthesis   
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Authors: Eirini Giannakopoulou , Madeleine Lehander , Stina Virding Culleton , Weiwen Yang , Yingqian Li , Terhi Karpanen , Tetsuichi Yoshizato , Even H Rustad , Morten Milek Nielsen , Ravi Chand Bollineni , Trung T Tran , Marina Delic-Sarac , Thea Johanne Gjerdingen , Karolos Douvlataniotis , Maarja Laos , Muhammad Ali , Amy Hillen , Stefania Mazzi , Desmond Wai Loon Chin , Adi Mehta , Jeppe Sejerø Holm , Amalie Kai Bentzen , Marie Bill , Marieke Griffioen , Tobias Gedde-Dahl, Sören Lehmann , Sten Eirik W Jacobsen , Petter S Woll , Johanna Olweus
Journal: Nat Cancer .
PubMed ID: 37783807
Doi: 10.1038/s43018-023-00642-8
Products & Services: Gene Synthesis   Peptide Synthesis   
Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2
Authors: Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz
Journal: PLoS Pathog
PubMed ID: 37856551
Doi: 10.1371/journal.ppat.1011728
Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection
Authors: Krystyna Cwiklinski, Amanda McEvoy, Jesús López Corrales, Heather Jewhurst, Nichola Eliza Davies Calvani, Carolina De Marco Verissimo, Amber Louise Dorey, Orla M Keane, John Pius Dalton, Richard Lalor
Journal: Vet Parasitol
PubMed ID: 37826973
Doi: 10.1016/j.vetpar.2023.110049
Identification and evaluation in-vitro of conserved peptides with high affinity to MHC-I as potential protective epitopes for Newcastle disease virus vaccines
Authors: Luis Tataje-Lavanda, Edith Málaga, Manuela Verastegui, Egma Mayta Huatuco, Eliana Icochea, Manolo Fernández-Díaz, Mirko Zimic
Journal: BMC Vet Res
PubMed ID: 37805566
Doi: 10.1186/s12917-023-03726-w
Products & Services: Molecular Biology Reagents   
A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity
Authors: Jackson Gabriel Miyamoto, Eduardo Shigueo Kitano, André Zelanis, Pedro Gabriel Nachtigall, Inácio Junqueira-de-Azevedo, Sávio Stefanini Sant'Anna, Rogério Lauria da Silva, Patrícia Alessandra Bersanetti, Adriana Karaoglanovic Carmona, Pedro José Barbosa Pereira, Solange M T Serrano, Maria Luiza Vilela Oliva, Alexandre Keiji Tashima
Journal: Biochimie
PubMed ID: 37839625
Doi: 10.1016/j.biochi.2023.10.010
Products & Services: Peptide Synthesis   
Sulforaphane alleviates the meiosis defects induced by 3-nitropropionic acid in mouse oocytes
Authors: Wei-Jian Li, Xuan Zhang, Ming Shen, Hong-Lin Liu, Li-Ren Ding
Journal: Food Chem Toxicol
PubMed ID: 37783421
Doi: 10.1016/j.fct.2023.114083
Products & Services: Molecular Biology Reagents   
Discovering human cell-compatible gene therapy virus variants via optimized screening in mouse models
Authors: Moyu Dai, Ning Yang, Kai Xu, Jingwen Zhang, Xueke Li, Ying Zhang, Wei Li
Journal: Cell Prolif
PubMed ID: 37864397
Doi: 10.1111/cpr.13565
T cells Use Focal Adhesions to Pull Themselves Through Confined Environments
Authors: Alexia Caillier, David Oleksyn, Deborah J Fowell, Jim Miller, Patrick W Oakes
Journal: biorxiv
PubMed ID: 37904911
Doi: 10.1101/2023.10.16.562587
Development of a counterselectable system for rapid and efficient CRISPR-based genome engineering in Zymomonas mobilis
Authors: Yanli Zheng, Hongmei Fu, Jue Chen, Jie Li, Yuejie Bian, Ping Hu, Lei Lei, Yihan Liu, Jiangke Yang, Wenfang Peng
Journal: Microb Cell Fact
PubMed ID: 37833755
Doi: 10.1186/s12934-023-02217-9
Rules and mechanisms governing G protein coupling selectivity of GPCRs
Authors: Ikuo Masuho , Ryoji Kise , Pablo Gainza , Ee Von Moo , Xiaona Li , Ryosuke Tany , Hideko Wakasugi-Masuho , Bruno E Correia , Kirill A Martemyanov
Journal: Cell Rep .
PubMed ID: 37742189
Doi: 10.1016/j.celrep.2023.113173
Products & Services: Gene Synthesis   
Evaluation and comparison of immune responses induced by two Mpox mRNA vaccine candidates in mice
Authors: Xidan Yang , Congxia Hu , Xuetao Yang , Xiu Yang , Xing Hu , Xingyun Wang , Cong Liu, Yuan Yuan , Shouwen Du , Peng George Wang, Jihui Lin
Journal: J Med Virol .
PubMed ID: 37800627
Doi: 10.1002/jmv.29140
Products & Services: Peptide Synthesis   
Horizontally transferred salivary protein promotes insect feeding by suppressing ferredoxin-mediated plant defenses
Authors: Yi-Zhe Wang , Yu-Xuan Ye , Jia-Bao Lu , Xin Wang , Hai-Bin Lu , Ze-Long Zhang , Zhuang-Xin Ye , Yu-Wen Lu , Zong-Tao Sun , Jian-Ping Chen , Jun-Min Li , Chuan-Xi Zhang , Hai-Jian Huang
Journal: Mol Biol Evol .
PubMed ID: 37804524
Doi: 10.1093/molbev/msad221
Products & Services: Catalog Antibody   
Rapid characterization of anti-CRISPR proteins and optogenetically engineered variants using a versatile plasmid interference system
Authors: Guoxu Song, Chunhong Tian, Jiahui Li, Fei Zhang, Yuxin Peng, Xing Gao and Yong Tian
Journal: Nucleic Acids Research
Doi: 10.1093/nar/gkad995
Products & Services: Gene Synthesis   
Establishment and characterization of a novel indirect ELISA method based on ASFV antigenic epitope-associated recombinant protein
Authors: Jiaxin Jin , Yilin Bai , Yuanyuan Zhang , Wenlong Lu , Shuai Zhang , Xuyang Zhao , Yaning Sun , Yanan Wu , Angke Zhang , Gaiping Zhang , Aijun Sun , Guoqing Zhuang
Journal: Int J Biol Macromol .
PubMed ID: 37865977
Doi: 10.1016/j.ijbiomac.2023.127311
Products & Services: Peptide Synthesis   
Structural and functional characterization of Aedes aegypti pupal cuticle protein that controls dengue virus infection
Authors: Qingqing Huang, Edem Gavor, Nikhil Kumar Tulsian, Jingsong Fan, Qingsong Lin, Yu Keung Mok, R Manjunatha Kini, J Sivaraman
Journal: Protein Sci
PubMed ID: 37593853
Doi: 10.1002/pro.4761
Products & Services: Codon Optimization   
MpADC, an L-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis
Authors: Pengfu Liu, Saixue Xie, Qian Guo, Yan Chen, Junying Fan, Ashok Kumar Nadda, Xiaoluo Huang, Xiaohe Chu
Journal: Biotechnol Biofuels Bioprod
PubMed ID: 37876019
Doi: 10.1186/s13068-023-02405-0
Author Correction: Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses
Authors: Xiuyuan Ou, Ge Xu, Pei Li, Yan Liu, Fuwen Zan, Pan Liu, Jiaxin Hu, Xing Lu, Siwen Dong, Yao Zhou, Zhixia Mu, Zhiqiang Wu, Jianwei Wang, Qi Jin, Pinghuang Liu, Jian Lu, Xiangxi Wang, Zhaohui Qian
Journal: Cell Discov
PubMed ID: 37813850
Doi: 10.1038/s41421-023-00597-1
G-quadruplexes of KSHV oriLyt play important roles in promoting lytic DNA replication
Authors: Prerna Dabral, Timsy Uppal, Subhash C Verma
Journal: Microbiol Spectr
PubMed ID: 37800915
Doi: 10.1128/spectrum.05316-22
Intradermal DNA vaccine delivery using vacuum-controlled, needle-free electroporation
Authors: Alison Generotti, Ryne Contreras, Brenden Zounes, Eric Schade, Andrea Kemme, Yatish Rane, Xinggang Liu, Dustin Elwood, Katherine Schultheis, Jeremy Marston, Jay McCoy, Kate Broderick, Paul Fisher
Journal: Mol Ther Nucleic Acids
PubMed ID: 38034030
Doi: 10.1016/j.omtn.2023.102070
Products & Services: Peptide Synthesis   
Tetravalent SARS-CoV-2 S1 subunit protein vaccination elicits robust humoral and cellular immune responses in SIV-infected rhesus macaque controllers
Authors: Muhammad S Khan, Eun Kim, Quentin Le Hingrat, Adam Kleinman, Alessandro Ferrari, Jose C Sammartino, Elena Percivalle, Cuiling Xu, Shaohua Huang, Thomas W Kenniston, Irene Cassaniti, Fausto Baldanti, Ivona Pandrea, Andrea Gambotto, Cristian Apetrei
Journal: MBio
PubMed ID: 37830800
Doi: 10.1128/mbio.02070-23
Products & Services: Molecular Biology Reagents   
Cryo-EM structure of severe fever with thrombocytopenia syndrome virus
Authors: Shouwen Du, Ruchao Peng, Wang Xu, Xiaoyun Qu, Yuhang Wang, Jiamin Wang, Letian Li, Mingyao Tian, Yudong Guan, Jigang Wang, Guoqing Wang, Hao Li, Lingcong Deng, Xiaoshuang Shi, Yidan Ma, Fengting Liu, Minhua Sun, Zhengkai Wei, Ningyi Jin, Wei Liu, Jianxun Qi, Quan Liu, Ming Liao, Chang Li
Journal: Nat Commun
PubMed ID: 37816705
Doi: 10.1038/s41467-023-41804-7
Products & Services: Peptide Synthesis   
SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition
Authors: Rachel Erickson, Chang Huang, Cameron Allen, Joanna Ireland, Gwynne Roth, Zhongcheng Zou, Jinghua Lu, Bernard A P Lafont, Nicole L Garza, Beniah Brumbaugh, Ming Zhao, Motoshi Suzuki, Lisa Olano, Joseph Brzostowski, Elizabeth R Fischer, Homer L Twigg, Reed F Johnson, Peter D Sun
Journal: Nat Commun
PubMed ID: 37821447
Doi: 10.1038/s41467-023-42140-6
Products & Services: Gene Synthesis   
Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs
Authors: Ghasidit Pornnoppadol, Layne G Bond, Michael J Lucas, Jennifer M Zupancic, Yun-Huai Kuo, Boya Zhang, Colin F Greineder, Peter M Tessier
Journal: Cell Chem Biol
PubMed ID: 37890480
Doi: 10.1016/j.chembiol.2023.09.008
Products & Services: Combinatorial DNA Libraries   
Evaluation of potential targets to enhance the sensitivity of cholangiocarcinoma cells to anticancer drugs
Authors: Paula Sanchon-Sanchez, Oscar Briz, Rocio I R Macias, Mar Abad, Anabel Sanchez-Martin, Jose J G Marin, Elisa Lozano
Journal: Biomed Pharmacother
PubMed ID: 37832404
Doi: 10.1016/j.biopha.2023.115658
Products & Services: Custom RNAi Services   
Chemoproteomic capture of RNA binding activity in living cells
Authors: Andrew J Heindel, Jeffrey W Brulet, Xiantao Wang, Michael W Founds, Adam H Libby, Dina L Bai, Michael C Lemke, David M Leace, Thurl E Harris, Markus Hafner, Ku-Lung Hsu
Journal: Nat Commun
PubMed ID: 37805600
Doi: 10.1038/s41467-023-41844-z
Products & Services: Mutant Libraries   
Investigation of Immunostimulatory Effects of IFN-γ Cytokine and CD40 Ligand Costimulatory Molecule for Development of HIV-1 Therapeutic Vaccine Candidate
Authors: Fatemeh Heidarnejad, Azam Bolhassani, Soheila Ajdary, Alireza Milani, Seyed Amir Sadeghi
Journal: Adv Biol (Weinh)
PubMed ID: 37840398
Doi: 10.1002/adbi.202300402
Products & Services: Molecular Biology Reagents   
Authentication of a lophotrochozoan adipokinetic hormone receptor in a Gastropod, Aplysia californica
Authors: Pei-San Tsai, Kelsey N Sanders, Xin Dai, David Plachetzki
Journal: Gen Comp Endocrinol
PubMed ID: 37865149
Doi: 10.1016/j.ygcen.2023.114393
Products & Services: Molecular Biology Reagents   
A non-canonical role of endothelin converting enzyme 1 (ECE1) in promoting lung cancer development via directly targeting protein kinase B (AKT)
Authors: Li Chen, Yikai Lu, Mengmeng Zhao, Junfang Xu, Yan Wang, Qinghua Xu, Yajuan Cao, Haipeng Liu
Journal: J Gene Med
PubMed ID: 37897251
Doi: 10.1002/jgm.3612
Folic acid alleviated oxidative stress-induced telomere attrition and inhibited apoptosis of neurocytes in old rats
Authors: Dezheng Zhou, Yue Sun, Cuixia Dong, Zehao Wang, Jing Zhao, Zhenshu Li, Guowei Huang, Wen Li
Journal: Eur J Nutr
PubMed ID: 37870657
Doi: 10.1007/s00394-023-03266-x
Products & Services: Gene Synthesis   
Antibodies elicited by Plasmodium falciparum circumsporozoite proteins lacking sequentially deleted C-terminal amino acids reveal mouse strain and epitopes specific differences
Authors: Clifford T H Hayashi, Yi Cao, Fidel Zavala, Hayk Simonyan, Colin N Young, Nirbhay Kumar
Journal: Vaccine
PubMed ID: 37827976
Doi: 10.1016/j.vaccine.2023.10.009
Products & Services: Gene Synthesis   
DETECTION OF SARS-COV-2 NEUTRALIZING ANTIBODIES IN RETROPHARYNGEAL LYMPH NODE EXUDATES OF WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS) FROM NEBRASKA, USA
Authors: Korakrit Poonsuk, Duan Loy, Rachael Birn, Bryan Buss, Matthew Donahue, Todd Nordeen, Kylie Sinclair, Luke Meduna, Bruce Brodersen, John Dustin Loy
Journal: J Wildl Dis
PubMed ID: 37768779
Doi: 10.7589/JWD-D-23-00005
Expression of a SAG protein with a CAP domain from Eimeria necatrix and its role in invasion and immunoprotection
Authors: Feiyan Wang, Amin Zhang, Xuelian Fan, Qianqian Feng, Zhizhi Zhang, Dandan Liu, Shijie Su, Zhaofeng Hou, Jinjun Xu, Xilong Kang, Zhiming Pan, Hunjie Hu, Jianping Tao
Journal: Vet Parasitol
PubMed ID: 37931477
Doi: 10.1016/j.vetpar.2023.110060
Flavivirus genome recoding by codon optimisation confers genetically stable in vivo attenuation in both mice and mosquitoes
Authors: Wei-Xin Chin, Hao Yuin Kong, Isabelle Xin Yu Zhu, Zi Yun Teo, Regina Faruk, Regina Ching Hua Lee, Si Xian Ho, Zhen Qin Aw, Bowen Yi, Xin Jun Hou, Antson Kiat Yee Tan, Thinesshwary Yogarajah, Roland G Huber, Yu Cai, Yue Wan, Justin Jang Hann Chu
Journal: PLoS Pathog
PubMed ID: 37883598
Doi: 10.1371/journal.ppat.1011753
Products & Services: Molecular Biology Reagents   
The cell-end protein Tea4 spatially regulates hyphal branch initiation and appressorium remodeling in the blast fungus
Authors: Audra Mae Rogers, Rachel Taylor, Martin John Egan
Journal: Mol Biol Cell
PubMed ID: 37903237
Doi: 10.1091/mbc.E23-06-0214
Products & Services: PCR Cloning and Subcloning   
Differential regulation of fibronectin expression and fibrillogenesis by autocrine TGF-β1 signaling in malignant and benign mammary epithelial cells
Authors: Michael M Sofroniou, Christopher A Lemmon
Journal: Int J Biochem Cell Biol
PubMed ID: 37866655
Doi: 10.1016/j.biocel.2023.106478
Products & Services: Stable Cell Lines   
Modulating biofilm can potentiate activity of novel plastic-degrading enzymes
Authors: Sophie A Howard, Ronan R McCarthy
Journal: NPJ Biofilms Microbiomes
PubMed ID: 37788986
Doi: 10.1038/s41522-023-00440-1
Products & Services: Gene Synthesis   
Development of CRISPR/Cas9-Based Genome Editing Tools for Polyploid Yeast Cyberlindnera jadinii and Its Application in Engineering Heterologous Steroid-Producing Strains
Authors: Lishan Gu, Rongxin Zhang, Xuqian Fan, Yu Wang, Kaiyu Ma, Jingjing Jiang, Gen Li, Honglei Wang, Feiyu Fan, Xueli Zhang
Journal: ACS Synth Biol
PubMed ID: 37816156
Doi: 10.1021/acssynbio.3c00278
Products & Services: Codon Optimization   
Novel ADAMTS13 mutations in a patient with congenital thrombotic thrombocytopenic purpura
Authors: Zhitao Wang, Xinhui Zhang, Xueqin Lu, Peng Peng, Huiru Wang, Shanglong Feng, Li Zhou
Journal: Hematology
PubMed ID: 37850618
Doi: 10.1080/16078454.2023.2269513
Modular multiwell viscoelastic hydrogel platform for two- and three-dimensional cell culture applications
Authors: Mackenzie L Skelton, James L Gentry, Leilani R Astrab, Joshua A Goedert, E Brynn Earl, Emily L Pham, Tanvi Bhat, Steven R Caliari
Journal: biorxiv
PubMed ID: 37873098
Doi: 10.1101/2023.10.09.561449
Tafluprost promotes axon regeneration after optic nerve crush via Zn-mTOR pathway
Authors: Siting Wu, Canying Liu, Jiahui Tang, Caiqing Wu, Qi Zhang, Zhe Liu, Jiaxu Han, Jingfei Xue, Jicheng Lin, Yuze Chen, Jinpeng Yang, Yehong Zhuo, Yiqing Li
Journal: Neuropharmacology
PubMed ID: 37832634
Doi: 10.1016/j.neuropharm.2023.109746

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