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Requires the Type II Secretion System for Pathogenicity and Survival in Grapevine

Authors: Brian Ingel, Claudia Castro, Lindsey Burbank, Nancy Her, N Itzel De Anda, Hannah Way, Peng Wang, M Caroline Roper

Journal: Mol Plant Microbe Interact

PubMed ID: 37188464

Doi: 10.1094/MPMI-03-23-0027-R

Products & Services: Gene Synthesis

Aggregative adherence fimbriae form compact structures as seen by SAXS

Authors: Rie Jønsson, Alexander Björling, Søren Roi Midtgaard, Grethe Vestergaard Jensen, Nicholas Skar-Gislinge, Lise Arleth, Steve Matthews, Karen Angeliki Krogfelt, Håvard Jenssen

Journal: Sci Rep

PubMed ID: 37783694

Doi: 10.1038/s41598-023-42079-0

Products & Services: Proteins, Expression, Isolation and Analysis

A morpheein equilibrium regulates catalysis in phosphoserine phosphatase SerB2 from Mycobacterium tuberculosis

Authors: Elise Pierson, Florian De Pol, Marianne Fillet, Johan Wouters

Journal: Commun Biol

PubMed ID: 37817000

Doi: 10.1038/s42003-023-05402-z

Products & Services: CRISPR Plasmids

MiR-143-3p/FNDC5 axis: a novel regulator of insulin sensitivity

Authors: Biao Li, Ying Dong, Siyuan Hu, Tiancai Liu

Journal: Endocrine

PubMed ID: 37815745

Doi: 10.1007/s12020-023-03522-4

Products & Services: DNA Sequencing

An in vitro-transcribed circular RNA targets the mitochondrial inner membrane cardiolipin to ablate EIF4G2/PTBP1 pan-adenocarcinoma

Authors: Zunyong Feng, Xuanbo Zhang, Jing Zhou, Qiang Li, Liuxi Chu, Guangfu Di, Zhengyuan Xu, Qun Chen, Ming Wang, Xiaochun Jiang, Hongping Xia, Xiaoyuan Chen

Journal: Nat Cancer

PubMed ID: 37845485

Doi: 10.1038/s43018-023-00650-8

Products & Services: DNA Sequencing

Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae

Authors: Yu-Min Li, Yu-Chao Mei, Ao-Hui Liu, Ru-Xin Wang, Runfa Chen, Hai-Ning Du

Journal: Cell Rep

PubMed ID: 37796660

Doi: 10.1016/j.celrep.2023.113186

Products & Services: Gene Synthesis

Differential modulation of cellular phenotype and drug sensitivity by extracellular matrix proteins in primary and metastatic pancreatic cancer cells

Authors: Olalekan H Usman, Sampath Kumar, Reddick R Walker, Gengqiang Xie, Hyeje C Sumajit, AbdelAziz R Jalil, Subramanian Ramakrishnan, Lawrence J Dooling, Yue Julia Wang, Jerome Irianto

Journal: Mol Biol Cell

PubMed ID: 37903222

Doi: 10.1091/mbc.E23-02-0075

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Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases

Authors: Shaojie Cui, Anchal Ghai, Yaqin Deng, Shili Li, Ruihui Zhang, Christopher Egbulefu, Guosheng Liang, Samuel Achilefu, Jin Ye

Journal: Mol Cell

PubMed ID: 37863053

Doi: 10.1016/j.molcel.2023.09.025

Products & Services: Molecular Biology Reagents

Propofol Promoted the Cell Growth and Epithelial Mesenchymal Transformation of the HTR-8/SVneo Cells through Targeting the METTL3 Mediated ZEB2

Authors: Long Cheng, Liang Zhao, Geng Wang

Journal: Reprod Sci

PubMed ID: 37814200

Doi: 10.1007/s43032-023-01368-9

Products & Services: Molecular Biology Reagents

Recombinant adeno-associated virus production evaluation in Chinese hamster ovary cells

Authors: Thu M Cao, Dayue Chen, Gavin C Barnard, Amy Shen

Journal: Biotechnol Bioeng

PubMed ID: 37902721

Doi: 10.1002/bit.28578

Products & Services: Proteins, Expression, Isolation and Analysis

Structure and function analysis of a type III preQ1-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence

Authors: Griffin M Schroeder , Daniil Kiliushik , Jermaine L Jenkins , Joseph E Wedekind

Journal: J Biol Chem .

PubMed ID: 37660906

Doi: 10.1016/j.jbc.2023.105208

Products & Services: Mutagenesis Services

A novel C-type lectin (SpccCTL) suppresses MCRV replication by binding viral protein and regulating antiviral peptides in Scylla paramamosain

Authors: Qing-Feng Yang, Shouhu Li, Guang-Peng Feng, Chuang Qin, Xiu-Wen Min, Wen-Hong Fang, Yue Wu, Jin Zhou, Xin-Cang Li

Journal: Fish Shellfish Immunol

PubMed ID: 37827249

Doi: 10.1016/j.fsi.2023.109143

Products & Services: Proteins, Expression, Isolation and Analysis

CRISPR/Cas9 System-Mediated Multi-copy Expression of an Alkaline Serine Protease in for the Production of XOD-Inhibitory Peptides

Authors: Shounan Wang, Yibin Xue, Peng Zhang, Qiaojuan Yan, Yanxiao Li, Zhengqiang Jiang

Journal: J Agric Food Chem

PubMed ID: 37807677

Doi: 10.1021/acs.jafc.3c04138

Products & Services: Proteins, Expression, Isolation and Analysis

Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies

Authors: Matthias Schmidt, Namil Lee, Chunjun Zhan, Jacob B Roberts, Alberto A Nava, Leah S Keiser, Aaron A Vilchez, Yan Chen, Christopher J Petzold, Robert W Haushalter, Lars M Blank, Jay D Keasling

Journal: ACS Synth Biol

PubMed ID: 37851920

Doi: 10.1021/acssynbio.3c00367

Products & Services: Proteins, Expression, Isolation and Analysis

Cornelia de Lange Syndrome mutations in SMC1A cause cohesion defects in yeast

Authors: Jingrong Chen, Erin N Floyd, Dean S Dawson, Susannah Rankin

Journal: Genetics

PubMed ID: 37650609

Doi: 10.1093/genetics/iyad159

Products & Services: Proteins, Expression, Isolation and Analysis

The CD4+ T cell repertoire specific for citrullinated peptides shows evidence of immune tolerance

Authors: Matthew K McElwee, Thamotharampillai Dileepan, Shawn A Mahmud, Marc K Jenkins

Journal: J Exp Med

PubMed ID: 37831103

Doi: 10.1084/jem.20230209

Products & Services: Peptide Synthesis

Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform

Authors: Alexander Ernst, Indre Piragyte, Ayisha Marwa Mp, Ngoc Dung Le, Denis Grandgirard, Stephen L Leib, Andrew Oates, Nadia Mercader

Journal: Sci Rep

PubMed ID: 37813860

Doi: 10.1038/s41598-023-43911-3

Products & Services: Molecular Biology Reagents

Allele-dependent expression and functionality of lipid enzyme PDAT affects diatom carbon storage and growth

Authors: Yufang Pan, Wanting Zhang, Xiaofei Wang, Juliette Jouhet, Eric Maréchal, Jin Liu, Xiao-Qin Xia, Hanhua Hu

Journal: Plant Physiol

PubMed ID: 37930282

Doi: 10.1093/plphys/kiad581

Products & Services: Monoclonal Antibody Services

Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells

Authors: Paalini Sathiyaseelan, Suganthi Chittaranjan, Steve E Kalloger, Jennifer Chan, Nancy E Go, Mario A Jardon, Cally J Ho, Theodore Hui, Jing Xu, Christine Chow, Dongxia Gao, Fraser D Johnson, William W Lockwood, Gregg B Morin, Daniel J Renouf, David F Schaeffer, Sharon M Gorski

Journal: J Cell Sci

PubMed ID: 37701987

Doi: 10.1242/jcs.260644

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The Exocyst Subunit CsExo70B Promotes Both Fruit Length and Disease Resistance via Regulating Receptor Kinase Abundance at Plasma Membrane in Cucumber

Authors: Liu Liu , Jiacai Chen , Chaoheng Gu , Shaoyun Wang , Yufan Xue , Zhongyi Wang , Lijie Han , Weiyuan Song , Xiaofeng Liu , Jiahao Zhang , Min Li , Chuang Li , Liming Wang , Xiaolan Zhang , Zhaoyang Zhou

Journal: Plant Biotechnol J .

PubMed ID: 37795910

Doi: 10.1111/pbi.14189

Products & Services: Peptide Synthesis

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

Authors: Eirini Giannakopoulou , Madeleine Lehander , Stina Virding Culleton , Weiwen Yang , Yingqian Li , Terhi Karpanen , Tetsuichi Yoshizato , Even H Rustad , Morten Milek Nielsen , Ravi Chand Bollineni , Trung T Tran , Marina Delic-Sarac , Thea Johanne Gjerdingen , Karolos Douvlataniotis , Maarja Laos , Muhammad Ali , Amy Hillen , Stefania Mazzi , Desmond Wai Loon Chin , Adi Mehta , Jeppe Sejerø Holm , Amalie Kai Bentzen , Marie Bill , Marieke Griffioen , Tobias Gedde-Dahl, Sören Lehmann , Sten Eirik W Jacobsen , Petter S Woll , Johanna Olweus

Journal: Nat Cancer .

PubMed ID: 37783807

Doi: 10.1038/s43018-023-00642-8

Products & Services: Gene Synthesis Peptide Synthesis

Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2

Authors: Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz

Journal: PLoS Pathog

PubMed ID: 37856551

Doi: 10.1371/journal.ppat.1011728

Products & Services: Proteins, Expression, Isolation and Analysis

Fasciola hepatica antioxidant and protease-inhibitor cocktail recombinant vaccines administered five times elicit potent and sustained immune responses in sheep but do not confer protection

Authors: Krystyna Cwiklinski, Amanda McEvoy, Jesús López Corrales, Heather Jewhurst, Nichola Eliza Davies Calvani, Carolina De Marco Verissimo, Amber Louise Dorey, Orla M Keane, John Pius Dalton, Richard Lalor

Journal: Vet Parasitol

PubMed ID: 37826973

Doi: 10.1016/j.vetpar.2023.110049

Products & Services: Proteins, Expression, Isolation and Analysis

Identification and evaluation in-vitro of conserved peptides with high affinity to MHC-I as potential protective epitopes for Newcastle disease virus vaccines

Authors: Luis Tataje-Lavanda, Edith Málaga, Manuela Verastegui, Egma Mayta Huatuco, Eliana Icochea, Manolo Fernández-Díaz, Mirko Zimic

Journal: BMC Vet Res

PubMed ID: 37805566

Doi: 10.1186/s12917-023-03726-w

Products & Services: Molecular Biology Reagents

A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity

Authors: Jackson Gabriel Miyamoto, Eduardo Shigueo Kitano, André Zelanis, Pedro Gabriel Nachtigall, Inácio Junqueira-de-Azevedo, Sávio Stefanini Sant'Anna, Rogério Lauria da Silva, Patrícia Alessandra Bersanetti, Adriana Karaoglanovic Carmona, Pedro José Barbosa Pereira, Solange M T Serrano, Maria Luiza Vilela Oliva, Alexandre Keiji Tashima

Journal: Biochimie

PubMed ID: 37839625

Doi: 10.1016/j.biochi.2023.10.010

Products & Services: Peptide Synthesis

Sulforaphane alleviates the meiosis defects induced by 3-nitropropionic acid in mouse oocytes

Authors: Wei-Jian Li, Xuan Zhang, Ming Shen, Hong-Lin Liu, Li-Ren Ding

Journal: Food Chem Toxicol

PubMed ID: 37783421

Doi: 10.1016/j.fct.2023.114083

Products & Services: Molecular Biology Reagents

Discovering human cell-compatible gene therapy virus variants via optimized screening in mouse models

Authors: Moyu Dai, Ning Yang, Kai Xu, Jingwen Zhang, Xueke Li, Ying Zhang, Wei Li

Journal: Cell Prolif

PubMed ID: 37864397

Doi: 10.1111/cpr.13565

Products & Services: Proteins, Expression, Isolation and Analysis

T cells Use Focal Adhesions to Pull Themselves Through Confined Environments

Authors: Alexia Caillier, David Oleksyn, Deborah J Fowell, Jim Miller, Patrick W Oakes

Journal: biorxiv

PubMed ID: 37904911

Doi: 10.1101/2023.10.16.562587

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a counterselectable system for rapid and efficient CRISPR-based genome engineering in Zymomonas mobilis

Authors: Yanli Zheng, Hongmei Fu, Jue Chen, Jie Li, Yuejie Bian, Ping Hu, Lei Lei, Yihan Liu, Jiangke Yang, Wenfang Peng

Journal: Microb Cell Fact

PubMed ID: 37833755

Doi: 10.1186/s12934-023-02217-9

Products & Services: Proteins, Expression, Isolation and Analysis

Rules and mechanisms governing G protein coupling selectivity of GPCRs

Authors: Ikuo Masuho , Ryoji Kise , Pablo Gainza , Ee Von Moo , Xiaona Li , Ryosuke Tany , Hideko Wakasugi-Masuho , Bruno E Correia , Kirill A Martemyanov

Journal: Cell Rep .

PubMed ID: 37742189

Doi: 10.1016/j.celrep.2023.113173

Products & Services: Gene Synthesis

Evaluation and comparison of immune responses induced by two Mpox mRNA vaccine candidates in mice

Authors: Xidan Yang , Congxia Hu , Xuetao Yang , Xiu Yang , Xing Hu , Xingyun Wang , Cong Liu, Yuan Yuan , Shouwen Du , Peng George Wang, Jihui Lin

Journal: J Med Virol .

PubMed ID: 37800627

Doi: 10.1002/jmv.29140

Products & Services: Peptide Synthesis

Horizontally transferred salivary protein promotes insect feeding by suppressing ferredoxin-mediated plant defenses

Authors: Yi-Zhe Wang , Yu-Xuan Ye , Jia-Bao Lu , Xin Wang , Hai-Bin Lu , Ze-Long Zhang , Zhuang-Xin Ye , Yu-Wen Lu , Zong-Tao Sun , Jian-Ping Chen , Jun-Min Li , Chuan-Xi Zhang , Hai-Jian Huang

Journal: Mol Biol Evol .

PubMed ID: 37804524

Doi: 10.1093/molbev/msad221

Products & Services: Catalog Antibody

Rapid characterization of anti-CRISPR proteins and optogenetically engineered variants using a versatile plasmid interference system

Authors: Guoxu Song, Chunhong Tian, Jiahui Li, Fei Zhang, Yuxin Peng, Xing Gao and Yong Tian

Journal: Nucleic Acids Research

Doi: 10.1093/nar/gkad995

Products & Services: Gene Synthesis

Establishment and characterization of a novel indirect ELISA method based on ASFV antigenic epitope-associated recombinant protein

Authors: Jiaxin Jin , Yilin Bai , Yuanyuan Zhang , Wenlong Lu , Shuai Zhang , Xuyang Zhao , Yaning Sun , Yanan Wu , Angke Zhang , Gaiping Zhang , Aijun Sun , Guoqing Zhuang

Journal: Int J Biol Macromol .

PubMed ID: 37865977

Doi: 10.1016/j.ijbiomac.2023.127311

Products & Services: Peptide Synthesis

Structural and functional characterization of Aedes aegypti pupal cuticle protein that controls dengue virus infection

Authors: Qingqing Huang, Edem Gavor, Nikhil Kumar Tulsian, Jingsong Fan, Qingsong Lin, Yu Keung Mok, R Manjunatha Kini, J Sivaraman

Journal: Protein Sci

PubMed ID: 37593853

Doi: 10.1002/pro.4761

Products & Services: Codon Optimization

A two-arm analysis of the immune response to heterologous boosting of inactivated SARS-CoV-2 vaccines

Authors: Arnone Nithichanon, Ludthawun Kamuthachad, Kanin Salao, Wisitsak Phoksawat, Chatcharin Kamsom, Surasakdi Wongratanacheewin, Chonlatip Pipattanaboon, Sakawrat Kanthawong, Umaporn Yordpratum, Sirinart Aromseree, Atibordee Meesing, Piroon Mootsikapun, Steven W Edwards, Supranee Phanthanawiboon

Journal: Sci Rep

PubMed ID: 37907584

Doi: 10.1038/s41598-023-46053-8

Products & Services: Molecular Biology Reagents

The cell-end protein Tea4 spatially regulates hyphal branch initiation and appressorium remodeling in the blast fungus

Authors: Audra Mae Rogers, Rachel Taylor, Martin John Egan

Journal: Mol Biol Cell

PubMed ID: 37903237

Doi: 10.1091/mbc.E23-06-0214

Products & Services: PCR Cloning and Subcloning

SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition

Authors: Rachel Erickson, Chang Huang, Cameron Allen, Joanna Ireland, Gwynne Roth, Zhongcheng Zou, Jinghua Lu, Bernard A P Lafont, Nicole L Garza, Beniah Brumbaugh, Ming Zhao, Motoshi Suzuki, Lisa Olano, Joseph Brzostowski, Elizabeth R Fischer, Homer L Twigg, Reed F Johnson, Peter D Sun

Journal: Nat Commun

PubMed ID: 37821447

Doi: 10.1038/s41467-023-42140-6

Products & Services: Gene Synthesis

Differential regulation of fibronectin expression and fibrillogenesis by autocrine TGF-β1 signaling in malignant and benign mammary epithelial cells

Authors: Michael M Sofroniou, Christopher A Lemmon

Journal: Int J Biochem Cell Biol

PubMed ID: 37866655

Doi: 10.1016/j.biocel.2023.106478

Products & Services: Stable Cell Lines

Modulating biofilm can potentiate activity of novel plastic-degrading enzymes

Authors: Sophie A Howard, Ronan R McCarthy

Journal: NPJ Biofilms Microbiomes

PubMed ID: 37788986

Doi: 10.1038/s41522-023-00440-1

Products & Services: Gene Synthesis

Development of CRISPR/Cas9-Based Genome Editing Tools for Polyploid Yeast Cyberlindnera jadinii and Its Application in Engineering Heterologous Steroid-Producing Strains

Authors: Lishan Gu, Rongxin Zhang, Xuqian Fan, Yu Wang, Kaiyu Ma, Jingjing Jiang, Gen Li, Honglei Wang, Feiyu Fan, Xueli Zhang

Journal: ACS Synth Biol

PubMed ID: 37816156

Doi: 10.1021/acssynbio.3c00278

Products & Services: Codon Optimization

MpADC, an L-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis

Authors: Pengfu Liu, Saixue Xie, Qian Guo, Yan Chen, Junying Fan, Ashok Kumar Nadda, Xiaoluo Huang, Xiaohe Chu

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 37876019

Doi: 10.1186/s13068-023-02405-0

Products & Services: Proteins, Expression, Isolation and Analysis

Author Correction: Host susceptibility and structural and immunological insight of S proteins of two SARS-CoV-2 closely related bat coronaviruses

Authors: Xiuyuan Ou, Ge Xu, Pei Li, Yan Liu, Fuwen Zan, Pan Liu, Jiaxin Hu, Xing Lu, Siwen Dong, Yao Zhou, Zhixia Mu, Zhiqiang Wu, Jianwei Wang, Qi Jin, Pinghuang Liu, Jian Lu, Xiangxi Wang, Zhaohui Qian

Journal: Cell Discov

PubMed ID: 37813850

Doi: 10.1038/s41421-023-00597-1

Products & Services: Proteins, Expression, Isolation and Analysis

G-quadruplexes of KSHV oriLyt play important roles in promoting lytic DNA replication

Authors: Prerna Dabral, Timsy Uppal, Subhash C Verma

Journal: Microbiol Spectr

PubMed ID: 37800915

Doi: 10.1128/spectrum.05316-22

Products & Services: Proteins, Expression, Isolation and Analysis

Expression of a SAG protein with a CAP domain from Eimeria necatrix and its role in invasion and immunoprotection

Authors: Feiyan Wang, Amin Zhang, Xuelian Fan, Qianqian Feng, Zhizhi Zhang, Dandan Liu, Shijie Su, Zhaofeng Hou, Jinjun Xu, Xilong Kang, Zhiming Pan, Hunjie Hu, Jianping Tao

Journal: Vet Parasitol

PubMed ID: 37931477

Doi: 10.1016/j.vetpar.2023.110060

Products & Services: Proteins, Expression, Isolation and Analysis

Quercetin ameliorates ferroptosis of rat cardiomyocytes via activation of the SIRT1/p53/SLC7A11 signaling pathway to alleviate sepsis‑induced cardiomyopathy

Authors: Xin Lin, Xiaoxia Zhao, Qingfeng Chen, Xiaoyue Wang, Yongya Wu, Hao Zhao

Journal: Int J Mol Med

PubMed ID: 37859612

Doi: 10.3892/ijmm.2023.5319

Products & Services: Proteins, Expression, Isolation and Analysis

Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs

Authors: Ghasidit Pornnoppadol, Layne G Bond, Michael J Lucas, Jennifer M Zupancic, Yun-Huai Kuo, Boya Zhang, Colin F Greineder, Peter M Tessier

Journal: Cell Chem Biol

PubMed ID: 37890480

Doi: 10.1016/j.chembiol.2023.09.008

Products & Services: Combinatorial DNA Libraries

Evaluation of potential targets to enhance the sensitivity of cholangiocarcinoma cells to anticancer drugs

Authors: Paula Sanchon-Sanchez, Oscar Briz, Rocio I R Macias, Mar Abad, Anabel Sanchez-Martin, Jose J G Marin, Elisa Lozano

Journal: Biomed Pharmacother

PubMed ID: 37832404

Doi: 10.1016/j.biopha.2023.115658

Products & Services: Custom RNAi Services

Chemoproteomic capture of RNA binding activity in living cells

Authors: Andrew J Heindel, Jeffrey W Brulet, Xiantao Wang, Michael W Founds, Adam H Libby, Dina L Bai, Michael C Lemke, David M Leace, Thurl E Harris, Markus Hafner, Ku-Lung Hsu

Journal: Nat Commun

PubMed ID: 37805600

Doi: 10.1038/s41467-023-41844-z

Products & Services: Mutant Libraries

Investigation of Immunostimulatory Effects of IFN-γ Cytokine and CD40 Ligand Costimulatory Molecule for Development of HIV-1 Therapeutic Vaccine Candidate

Authors: Fatemeh Heidarnejad, Azam Bolhassani, Soheila Ajdary, Alireza Milani, Seyed Amir Sadeghi

Journal: Adv Biol (Weinh)

PubMed ID: 37840398

Doi: 10.1002/adbi.202300402

Products & Services: Molecular Biology Reagents

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