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Anti-HIV Humoral Response Induced by Different Anti-Idiotype Antibody Formats: An In Silico and In Vivo Approach
Authors: Valeria Caputo, Ilaria Negri, Louiza Moudoud, Martina Libera, Luigi Bonizzi, Massimo Clementi, Roberta Antonia Diotti
Journal: Int J Mol Sci
PubMed ID: 38891926
Doi: 10.3390/ijms25115737
Products & Services: Molecular Biology Reagents   
Impact of N-Glycosylation on Protein Structure and Dynamics Linked to Enzymatic C–H Activation in the M. oryzae Lipoxygenase
Authors: Chris Whittington, Ajay Sharma, S Gage Hill, Anthony T Iavarone, Brian M Hoffman, Adam R Offenbacher
Journal: Biochemistry
PubMed ID: 38690768
Doi: 10.1021/acs.biochem.4c00109
Products & Services: Mutagenesis Services   
Manganese-dependent transcription regulation by MntR and PerR in Thermus thermophilus HB8
Authors: John K Barrows, Kamya A Stubbs, Irina F Padilla-Montoya, Thomas C Leeper, Michael W Van Dyke
Journal: Mol Microbiol
PubMed ID: 38735869
Products & Services: Nucleic Acid Purification   
Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA
Authors: Fangting Zuo, Li Jiang, Ni Su, Yaqiang Zhang, Bingkun Bao, Limei Wang, Yajie Shi, Huimin Yang, Xinyi Huang, Ruilong Li, Qingmei Zeng, Zhengda Chen, Qiuning Lin, Yingping Zhuang, Yuzheng Zhao, Xianjun Chen, Linyong Zhu & Yi Yang
Journal: nature chemical biology
PubMed ID: 38783134
Doi: 10.1038/s41589-024-01629-x
Products & Services: CRISPR KI Templates   
Quercetin induces itaconic acid-mediated M1/M2 alveolar macrophages polarization in respiratory syncytial virus infection
Authors: Li An , Qianwen Zhai , Keyu Tao , Yingcai Xiong , Weiying Ou , Ziwei Yu , Xingyu Yang , Jianjian Ji , Mengjiang Lu
Journal: Phytomedicine
PubMed ID: 38797031
Doi: 10.1016/j.phymed.2024.155761
Products & Services: Protein Electrophoresis and Western   
Identification of Fibrinogen as a Plasma Protein Binding Partner for Lecanemab Biosimilar IgG: Implications for Alzheimer's Disease Therapy
Authors: Jean-Pierre Bellier, Andrea Roman, Caitlyn Christiano, Juliana Au Anzai, Stephanie Moreno, Emily C Campbell, Lucas Godwin, Amy Li, Alan Chen, Sarah M Alan, Adriana Saba, Han Bin Yoo, Hyun-Sik Yang, Jasmeer P Chhatwal, Dennis J Selkoe, Lei Liu
Journal: biorxiv
PubMed ID: 38746192
Doi: 10.1101/2024.05.01.591892
Products & Services: Protein Electrophoresis and Western   
Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren's syndrome in mice by promoting TEC kinase degradation
Authors: Ya-Qi Yang, Yi-Jun Liu, Wen-Xuan Qiao, Wei Jin, Shun-Wei Zhu, Yu-Xi Yan, Qiong Luo, Qiang Xu
Journal: Acta Pharmacol Sin
PubMed ID: 38744938
Doi: 10.1038/s41401-024-01288-7
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Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement
Authors: Seiji Watanabe, Kangsa Amporndanai, Raheela Awais, Caroline Latham, Muhammad Awais, Paul M O'Neill, Koji Yamanaka, S Samar Hasnain
Journal: Sci Rep
PubMed ID: 38802492
Doi: 10.1038/s41598-024-62903-5
Products & Services: Gene Synthesis   
Molecular characteristics of Echinococcus multilocularis FABP1 and its regulatory functions on murine macrophages
Authors: Xiang Li, Peng Liao, Wenjing Zhou, Xinqi Yang, Bin Ye
Journal: Acta Trop
PubMed ID: 38729330
Doi: 10.1016/j.actatropica.2024.107247
Products & Services: Protein and Antibody Isolation   
Fluorescence Sensing of Eclampsia Biomarkers via the Immunosorbent Atom Transfer Radical Polymerization Assay
Authors: Nan Ma, Jian Zhang, Jinming Kong, Xueji Zhang
Journal: Anal Chem
PubMed ID: 38728011
Doi: 10.1021/acs.analchem.4c00110
Products & Services: Protein and Antibody Isolation   
Elucidation of the Catalytic Sequence of Dihydroorotate Dehydrogenase B from : Evidence for Accumulation of a Flavin Bisemiquinone State in Catalysis
Authors: Corine O Smith, Graham R Moran
Journal: Biochemistry
PubMed ID: 38691339
Doi: 10.1021/acs.biochem.4c00025
Products & Services: Gene Synthesis   
A ferritin nanoparticle vaccine based on the hemagglutinin extracellular domain of swine influenza A (H1N1) virus elicits protective immune responses in mice and pigs
Authors: Pan Tang, Enhui Cui, Jinghua Cheng, Benqiang Li, Jie Tao, Ying Shi, Jiajie Jiao, Enqi Du, Jingyu Wang, Huili Liu
Journal: Front Immunol
PubMed ID: 38835763
Doi: 10.3389/fimmu.2024.1361323
Products & Services: Codon Optimization   
Structural insights into the molecular mechanism of phytoplasma immunodominant membrane protein
Authors: Chang Yi Liu, Han Pin Cheng, Chan Pin Lin, Yi Ting Liao, Tzu Ping Ko, Shin Jen Lin, Shih Shun Lin, Hao Ching Wang
Journal: IUCrJ
PubMed ID: 38656311
Doi: 10.1107/S2052252524003075
Products & Services: Molecular Biology Reagents   
Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL316 of herpes simplex virus 1
Authors: Akihisa Kato, Ryoji Iwasaki, Kousuke Takeshima, Yuhei Maruzuru, Naoto Koyanagi, Tohru Natsume, Hideo Kusano, Shungo Adachi, Shuichi Kawano, Yasushi Kawaguchi
Journal: J Virol
PubMed ID: 38819171
Doi: 10.1128/jvi.00747-24
Products & Services: Gene Synthesis   
Mutation of SIVA, a candidate metastasis gene identified from clonally related bilateral breast cancers, promotes breast cancer cell spread in vitro and in vivo
Authors: Anke Vermehren-Schmaedick, Myron Peto, Wendy Wagoner, Kami E Chiotti, Elizabeth Ramsey, Xiaoyan Wang, Shauna Rakshe, Jessica Minnier, Rosalie Sears, Paul Spellman, Shiuh-Wen Luoh
Journal: PLoS ONE
PubMed ID: 38722955
Doi: 10.1371/journal.pone.0302856
Products & Services: PCR Cloning and Subcloning   
Development and application of a cycleave dual-probe fluorescence quantitative PCR method for simultaneous detection of Mycoplasma gallisepticum ts-11 vaccine strain and non-ts-11 strains
Authors: Xue Wang, Nana Sun, Meng Wang, Hui Wang, Yuhan Liu, Hao Shi, Hao Zhu, Peidong Li, Fuyou Zhang, Tianyao Yang, Zhaoyang Li, Chunguo Liu
Journal: Poult Sci
PubMed ID: 38878745
Doi: 10.1016/j.psj.2024.103907
Products & Services: PCR Cloning and Subcloning   
Radiation-primed TGF-β trapping by engineered extracellular vesicles for targeted glioblastoma therapy
Authors: Ruyu Liang, Hongyu Lu, Haifeng Zhu, Gaofeng Liang, Junxia Zhang, Jun Gao, Tian Tian
Journal: J Control Release
PubMed ID: 38740092
Doi: 10.1016/j.jconrel.2024.05.022
Products & Services: DNA Sequencing   
Delivery of endolysin across outer membrane of Gram-negative bacteria using translocation domain of botulinum neurotoxin
Authors: Wonbeom Park, Myungseo Park, Jihwan Chun, Jaehyeon Hwang, Suhyun Kim, Nayoon Choi, Soo Min Kim, SeungJoo Kim, Sangwon Jung, Kwan Soo Ko, Dae-Hyuk Kweon
Journal: Int J Antimicrob Agents
PubMed ID: 38795926
Doi: 10.1016/j.ijantimicag.2024.107216
Products & Services: DNA Sequencing   
CRISPR/Cas9-Mediated Knockout of the Lycopene ε-Cyclase for Efficient Astaxanthin Production in the Green Microalga
Authors: Jacob Sebastian Kneip, Niklas Kniepkamp, Junhwan Jang, Maria Grazia Mortaro, EonSeon Jin, Olaf Kruse, Thomas Baier
Journal: Plants (Basel)
PubMed ID: 38794462
Doi: 10.3390/plants13101393
Products & Services: PCR Cloning and Subcloning   Gene Synthesis   
Development of a Plant-Expressed Subunit Vaccine against Brucellosis
Authors: Daria A Rutkowska, Lissinda H Du Plessis, Essa Suleman, Martha M O'Kennedy, Deepak B Thimiri Govinda Raj, Yolandy Lemmer
Journal: Microorganisms
PubMed ID: 38930429
Doi: 10.3390/microorganisms12061047
Products & Services: Catalog Peptides   
Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
Authors: Jeannette L Tenthorey, Serena Del Banco, Ishrak Ramzan, Hayley Klingenberg, Chang Liu, Michael Emerman, Harmit S Malik
Journal: biorxiv
PubMed ID: 38765965
Doi: 10.1101/2024.05.07.592993
Products & Services: PCR Cloning and Subcloning   
Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia
Authors: Nuchjira Takheaw, Kamonporn Kotemul, Ratthakorn Chaiwut, Supansa Pata, Witida Laopajon, Kuntalee Rangnoi, Montarop Yamabhai, Watchara Kasinrerk
Journal: Antibodies (Basel)
PubMed ID: 38804310
Doi: 10.3390/antib13020042
Products & Services: Catalog Peptides   
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase
Authors: Garrett L Schey, Emily R Hildebrandt, You Wang, Safwan Diwan, Holly A Passetti, Gavin W Potts, Andrea M Sprague-Getsy, Ethan R Leoni, Taylor S Kuebler, Yuk Y Sham, James L Hougland, Lorena S Beese, Walter K Schmidt, Mark D Distefano
Journal: Int J Mol Sci
PubMed ID: 38791363
Doi: 10.3390/ijms25105324
Products & Services: Catalog Peptides   
Imprinted lncRNA KCNQ1OT1 regulates CDKN1C expression through promoter binding and chromatin folding in pigs
Authors: Yongfeng Zhou, Hao Yu, Daoyu Zhang, Zhengzhu Wang, Qi Li, Xinglan An, Sheng Zhang, Ziyi Li
Journal: Gene
PubMed ID: 38772516
Doi: 10.1016/j.gene.2024.148590
Products & Services: Protein and Antibody Isolation   
Identification of phosphorylated small ORF-encoded peptides in Hep3B cells by LC/MS/MS
Authors: Mingbo Peng, Yutian Zhou, Cuihong Wan
Journal: J Proteomics
PubMed ID: 38823442
Doi: 10.1016/j.jprot.2024.105214
Products & Services: Catalog Peptides   
A new strategy to generate nanobodies for the coumaphos based on the synthesized nanobody libraries
Authors: Ruyu Fang, Yingxue Li, Fei Liu, Yifan Liang, Yu Wang, Guohua Zhong, Zhenlin Xu, Bruce D Hammock, Hong Wang
Journal: Food Chem
PubMed ID: 38833869
Doi: 10.1016/j.foodchem.2024.139684
Production of VP3-only virus-like particles of Adeno-associated virus 2 in E coli cells
Authors: Chengyu Fu, Shruthi Gobbooru, Ashley T Martino, Woon-Kai Low
Journal: Protein Expr Purif
PubMed ID: 38754753
Doi: 10.1016/j.pep.2024.106502
Products & Services: Catalog Antibodies   
Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis
Authors: Zhixin Ma, Yu Sun, Yang Yu, Wenjun Xiao, Zhijie Xiao, Tianyu Zhong, Xi Xiang, Zhigang Li
Journal: Cell Commun Signal
PubMed ID: 38802814
Doi: 10.1186/s12964-024-01669-9
Development of a Selective and Stable Antimicrobial Peptide
Authors: Kyra E. Groover; Justin R. Randall; Bryan W. Davies
Journal: ACS Infectious Diseases
PubMed ID: 38712889
Doi: 10.1021/acsinfecdis.4c00142
Products & Services: Peptide Synthesis   
Computational design of generalist cyclopropanases with stereodivergent selectivity
Authors: Zhuofan Shen; Mary G. Siriboe; Xinkun Ren; Thakshila Dayananda; Jermaine L. Jenkins; Sagar D. Khare; Rudi Fasan
Journal: Nature Communications
PubMed ID: 41587967
Doi: 10.1038/s41467-026-68327-1
Computational design of generalist cyclopropanases with stereodivergent selectivity
Authors: Zhuofan Shen; Mary G. Siriboe; Xinkun Ren; Thakshila Dayananda; Jermaine L. Jenkins; Sagar D. Khare; Rudi Fasan
Journal: Nature Communications
PubMed ID: 41587967
Doi: 10.1038/s41467-026-68327-1
Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics
Authors: Jiyun Zhu; Alexandria M. Kemp; Bala C. Chenna; Vivek Kumar; Andrew Rademacher; Sangho Yun; Arthur Laganowsky; Thomas D. Meek
Journal: ACS catalysis
PubMed ID: 39722883
Doi: 10.1021/acscatal.4c04695
Bioinformatic prediction and experimental validation of RiPP recognition elements
Authors: Kyle E. Shelton; Douglas A. Mitchell
Journal: Methods in enzymology
PubMed ID: 36682862
Doi: 10.1016/bs.mie.2022.08.050
Bioinformatic prediction and experimental validation of RiPP recognition elements
Authors: Kyle E. Shelton; Douglas A. Mitchell
Journal: Methods in enzymology
PubMed ID: 36682862
Doi: 10.1016/bs.mie.2022.08.050
Bioinformatic prediction and experimental validation of RiPP recognition elements
Authors: Kyle E. Shelton; Douglas A. Mitchell
Journal: Methods in enzymology
PubMed ID: 36682862
Doi: 10.1016/bs.mie.2022.08.050
Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells
Authors: Renate L M Jansen, Rinse de Boer, Eline M F de Lange, Janet Koster, Rifka Vlijm, Hans R Waterham, Ida J van der Klei
Journal: Biochim Biophys Acta Mol Cell Res
PubMed ID: 38762172
Doi: 10.1016/j.bbamcr.2024.119754
Products & Services: Molecular Biology Reagents   
Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants
Authors: Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson, Thea K. Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L. Powell, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen & Rasmus Hartmann-Petersen
Journal: Nat Commun
PubMed ID: 38740822
Doi: 10.1038/s41467-024-48481-0
Products & Services: Mutagenesis Services   
Biosynthetic production of anticoagulant heparin polysaccharides through metabolic and sulfotransferases engineering strategies
Authors: Jian-Qun Deng, Yi Li, Yu-Jia Wang, Ya-Lin Cao, Si-Yu Xin, Xin-Yu Li, Rui-Min Xi, Feng-Shan Wang & Ju-Zheng Sheng
Journal: Nat Commun
PubMed ID: 38704385
Doi: 10.1038/s41467-024-48193-5
Products & Services: Gene Synthesis   
Single-molecule assay guided crRNA optimization enhances specific microRNA detection by CRISPR-Cas12a
Authors: Kaizhao Chen, Wenjun Sun, Mingtian Zhong, Jiaqi Xie, Yongkun Huo, Xiuqi Lu, Ziting Chen, Bo Sun, Xingxu Huang, Xinjie Wang, Ming Liu , Xiaodong Ma, Peixiang Ma
Journal: Sensors and Actuators B: Chemical
Doi: 10.1016/j.snb.2024.135389
Products & Services: Protein Electrophoresis and Western   
C9orf72-Associated Dipeptide Repeat Expansions Perturb ER-Golgi Vesicular Trafficking, Inducing Golgi Fragmentation and ER Stress, in ALS/FTD
Authors: Jessica Sultana, Audrey M G Ragagnin, Sonam Parakh, Sayanthooran Saravanabavan, Kai Ying Soo, Marta Vidal, Cyril Jones Jagaraj, Kunjie Ding, Sharlynn Wu, Sina Shadfar, Emily K Don, Anand Deva, Garth Nicholson, Dominic B Rowe, Ian Blair, Shu Yang, Julie D Atkin
Journal: Mol Neurobiol
PubMed ID: 38722513
Doi: 10.1007/s12035-024-04187-4
Products & Services: PCR Cloning and Subcloning   
Polyglutamine-mediated ribotoxicity disrupts proteostasis and stress responses in Huntington's disease
Authors: Ranen Aviner, Ting-Ting Lee, Vincent B Masto, Kathy H Li, Raul Andino, Judith Frydman
Journal: Nat Cell Biol
PubMed ID: 38741019
Doi: 10.1038/s41556-024-01414-x
Products & Services: ORF cDNA Clones/MolecularCloud   
A PACAP-activated network for secretion requires coordination of Ca influx and Ca mobilization
Authors: Xiaohuan Chen, Nicole A Bell, Breanna L Coffman, Agustin A Rabino, Rafael Garcia-Mata, Paul J Kammermeier, David I Yule, Daniel Axelrod, Alan V Smrcka, David R Giovannucci, Arun Anantharam
Journal: Mol Biol Cell
PubMed ID: 38758660
Doi: 10.1091/mbc.E24-02-0083
Products & Services: Molecular Biology Reagents   
Disulfidptosis in head and neck squamous carcinoma: Integrative bioinformatic and in-vitro analysis
Authors: Xufeng Huang, Jinyan Yang, Qi Wang, Rao Fu, Xutao Wen, Zhengrui Li, Ling Zhang
Journal: Oral Dis
PubMed ID: 38696646
Doi: 10.1111/odi.14977
Products & Services: Molecular Biology Reagents   
Two-point immobilization of M3 muscarinic receptor: a method for recognizing receptor antagonists in natural products
Authors: Xiaomin Huang, Ting Wang, Ludan Wang, Yantao Sun, Ziru Zhang, Yajun Zhang
Journal: BMC Chem
PubMed ID: 38702791
Doi: 10.1186/s13065-024-01198-z
Products & Services: DNA Sequencing   
Lysineless HiBiT and NanoLuc Tagging Systems as Alternative Tools Monitoring Targeted Protein Degradation
Authors: Hanfeng Lin, Kristin Riching, May Poh Lai, Dong Lu, Ran Cheng, Xiaoli Qi, Jin Wang
Journal: biorxiv
PubMed ID: 38798562
Doi: 10.1101/2024.05.14.594249
Products & Services: Molecular Biology Reagents   
Novel enzymes for biodegradation of polycyclic aromatic hydrocarbons identified by metagenomics and functional analysis in short-term soil microcosm experiments
Authors: Kinga K Nagy, Kristóf Takács, Imre Németh, Bálint Varga, Vince Grolmusz, Mónika Molnár, Beáta G Vértessy
Journal: Sci Rep
PubMed ID: 38773163
Doi: 10.1038/s41598-024-61566-6
Products & Services: Gene Synthesis   
Nonspecific phospholipases C3 and C4 interact with PIN-FORMED2 to regulate growth and tropic responses in Arabidopsis
Authors: Teng Li, Shujuan Zhang, Shuaibing Yao, Xuebing Li, Qianru Jia, Jingya Yuan, Wenhua Zhang, Xuemin Wang, Qun Zhang
Journal: Plant Cell
PubMed ID: 38442314
Doi: 10.1093/plcell/koae071
Products & Services: Protein and Antibody Isolation   
Structural characterization of E22G Aβ fibrils H detected MAS NMR
Authors: Natalie C Golota, Brian Michael, Edward P Saliba, Sara Linse, Robert G Griffin
Journal: Phys Chem Chem Phys
PubMed ID: 38715538
Doi: 10.1039/d4cp00553h
Products & Services: Molecular Biology Reagents   
Arg-biodynamers as antibiotic potentiators through interacting with Gram-negative outer membrane lipopolysaccharides
Authors: Mohamed A M Kamal, Justine Bassil, Brigitta Loretz, Anna K H Hirsch, Sangeun Lee, Claus-Michael Lehr
Journal: Eur J Pharm Biopharm
PubMed ID: 38795784
Doi: 10.1016/j.ejpb.2024.114336
Products & Services: Catalog Peptides   
Deletion of Asb15b gene can lead to a significant decrease in zebrafish intermuscular bone
Authors: Minghui Niu, Huamin Whang, Zhichao Wu, Shouwen Jiang, Liangbiao Chen
Journal: Gene
PubMed ID: 38754570
Doi: 10.1016/j.gene.2024.148561
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