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Targeting the COMMD4-H2B protein complex in lung cancer

Authors: Ming Tang, Joshua T Burgess, Mark Fisher, Didier Boucher, Emma Bolderson, Neha S Gandhi, Kenneth J O'Byrne, Derek J Richard, Amila Suraweera

Journal: Br J Cancer

PubMed ID: 37914802

Doi: 10.1038/s41416-023-02476-8

Products & Services: Proteins, Expression, Isolation and Analysis

Regioselective Glycosylation of Polyphenols by Family 1 Glycosyltransferases: Experiments and Simulations

Authors: Ruben M de Boer, Dovydas Vaitkus, Kasper Enemark-Rasmussen, Sören Maschmann, David Teze, Ditte H Welner

Journal: ACS Omega

PubMed ID: 38075805

Doi: 10.1021/acsomega.3c08255

Products & Services: Proteins, Expression, Isolation and Analysis

Extracellular electron uptake from a cathode by the lactic acid bacterium

Authors: Sara Tejedor-Sanz, Siliang Li, Biki Bapi Kundu, Caroline M Ajo-Franklin

Journal: Front Microbiol

PubMed ID: 38075918

Doi: 10.3389/fmicb.2023.1298023

Products & Services: Molecular Biology Reagents

Comparative Computational Analysis of Spike Protein Structural Stability in SARS-CoV-2 Omicron Subvariants

Authors: Anand Balupuri, Jeong-Min Kim, Kwang-Eun Choi, Jin Sun No, Il-Hwan Kim, Jee Eun Rhee, Eun-Jin Kim, Nam Sook Kang

Journal: Int J Mol Sci

PubMed ID: 38003257

Doi: 10.3390/ijms242216069

Products & Services: Molecular Biology Reagents

The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells

Authors: Jing Cheng, Yutong Wang, Lizheng Yin, Wenzhang Liang, Jing Zhang, Cuiqing Ma, Yu Zhang, Bo Liu, Jiachao Wang, Weiting Zhao, Miao Li, Lin Wei

Journal: MBio

PubMed ID: 37909764

Doi: 10.1128/mbio.01480-23

Products & Services: Molecular Biology Reagents

IRGM is a novel regulator of PD-L1 via promoting S6K1-mediated phosphorylation of YBX1 in hepatocellular carcinoma

Authors: Junnan Ru, Jiahua Lu, Jiangzhen Ge, Bo Ding, Rong Su, Yifan Jiang, Yujing Sun, Jun Ma, Yu Li, Jingqi Sun, Guangming Xu, Rongliang Tong, Shusen Zheng, Beng Yang, Jian Wu

Journal: Cancer Lett

PubMed ID: 37993085

Doi: 10.1016/j.canlet.2023.216495

Products & Services: Recombinant Antibody Expression

Mechanism of actin capping protein recruitment and turnover during clathrin-mediated endocytosis

Authors: Andrew K Lamb, Andres N Fernandez, Abdunaser Eadaim, Katelyn Johnson, Santiago M Di Pietro

Journal: J Cell Biol

PubMed ID: 37966720

Doi: 10.1083/jcb.202306154

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Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry

Authors: Haofeng Wang, Qi Yang, Xiaoce Liu, Zili Xu, Maolin Shao, Dongxu Li, Yinkai Duan, Jielin Tang, Xianqiang Yu, Yumin Zhang, Aihua Hao, Yajie Wang, Jie Chen, Chenghao Zhu, Luke Guddat, Hongli Chen, Leike Zhang, Xinwen Chen, Biao Jiang, Lei Sun, Zihe Rao, Haitao Yang

Journal: Nat Commun

PubMed ID: 37990007

Doi: 10.1038/s41467-023-42527-5

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Retraction: Epitopes screening and vaccine molecular design of SADS-CoV based on immunoinformatics

Authors:

Journal: Front Vet Sci

PubMed ID: 38105774

Doi: 10.3389/fvets.2023.1342203

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Delineation of DNA and mRNA COVID-19 vaccine-induced immune responses in preclinical animal models

Authors: Viviane M Andrade, Igor Maricic, Richa Kalia, Lauren Jachimowicz, Olivia Bedoya, Daniel W Kulp, Laurent Humeau, Trevor R F Smith

Journal: Hum Vaccin Immunother

PubMed ID: 38012018

Doi: 10.1080/21645515.2023.2281733

Products & Services: Plasmids for SARS-CoV-2 Detection and Research

Antagonistic conflict between transposon-encoded introns and guide RNAs

Authors: Rimantė Žedaveinytė, Chance Meers, Hoang C Le, Edan E Mortman, Stephen Tang, George D Lampe, Sanjana R Pesari, Diego R Gelsinger, Tanner Wiegand, Samuel H Sternberg

Journal: biorxiv

PubMed ID: 38045383

Doi: 10.1101/2023.11.20.567912

Products & Services: Molecular Biology Reagents

A Versatile Platform to Generate Prodrugs with Rapid and Precise Albumin Hitchhiking and High Cargo Loading for Tumor-Targeted Chemotherapy

Authors: Jing Li, Huimin Xing, Jie Chen, Hongyu Lu, Ze Tao, Yiran Tao, Yunqing Sun, Tao Su, Xin Li, Huansheng Chang, Shiyuan Chen, Zhuo Chen, Hao Yang, Jingqiu Cheng, Hong Zhu, Xiaofeng Lu

Journal: Small

PubMed ID: 37963821

Doi: 10.1002/smll.202304253

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Novel and unique rheumatoid factors cross-react with viral epitopes in COVID-19

Authors: Maya F Amjadi, Maxwell H Parker, Ryan R Adyniec, Zihao Zheng, Alex M Robbins, S Janna Bashar, Michael F Denny, Sara S McCoy, Irene M Ong, Miriam A Shelef

Journal: J Autoimmun

PubMed ID: 37956528

Doi: 10.1016/j.jaut.2023.103132

Products & Services: Proteins, Expression, Isolation and Analysis

Oncolytic adenoviruses expressing checkpoint inhibitors for cancer therapy

Authors: Daoyuan Xie , Yaomei Tian , Die Hu , Yuanda Wang , Yuling Yang , Bailing Zhou , Rui Zhang , Zhixiang Ren , Mohan Liu , Jie Xu , Chunyan Dong , Binyan Zhao , Li Yang

Journal: Signal Transduct Target Ther .

PubMed ID: 38016957

Doi: 10.1038/s41392-023-01683-2

Products & Services: Proteins, Expression, Isolation and Analysis

Structural insights into asymmetric activation of the calciumsensing receptor–Gq complex

Authors: Shenglong Ling, Xianyu Meng, Yuan Zhang, Zhemin Xia, Yingxin Zhou, Fan Yang, Pan Shi, Chaowei Shi, Changlin Tian

Journal: Cell Res .

PubMed ID: 37919470

Doi: 10.1038/s41422-023-00892-2

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Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations

Authors: Brittany N Williams, Adam Draper, Patrick F Lang, Tylor R Lewis, Audrey L Smith, Steven J Mayerl, Marie Rougié, Jeremy M Simon, Vadim Y Arshavsky, Scott H Greenwald, David M Gamm, Isabel Pinilla, Benjamin D Philpot

Journal: Hum Mol Genet

PubMed ID: 37975905

Doi: 10.1093/hmg/ddad199

Products & Services: Proteins, Expression, Isolation and Analysis

Reconstruction of dynamic mammary mini gland in vitro for normal physiology and oncogenesis

Authors: Lei Yuan, Shaofang Xie, Huiru Bai, Xiaoqin Liu, Pei Cai, Jing Lu, Chunhui Wang, Zuobao Lin, Shuying Li, Yajing Guo, Shang Cai

Journal: Nat Methods

PubMed ID: 37919421

Doi: 10.1038/s41592-023-02039-y

Products & Services: Proteins, Expression, Isolation and Analysis

IL-27 regulates NLRP3 inflammasome activation of MDSCs in experimental Sjögren's syndrome

Authors: Xiaoyu Xia, Qiqiang Long, Jie Zha, Tingting Jiang, Junqiao Guo, Bo Jiang, Xiaojing Li, Genhong Yao

Journal: Int Immunol

PubMed ID: 37756640

Doi: 10.1093/intimm/dxad037

Products & Services: Molecular Biology Reagents

Autoimmune amelogenesis imperfecta in patients with APS-1 and coeliac disease

Authors: Yael Gruper, Anette S B Wolff, Liad Glanz, Frantisek Spoutil, Mihaela Cuida Marthinussen, Adriana Osickova, Yonatan Herzig, Yael Goldfarb, Goretti Aranaz-Novaliches, Jan Dobeš, Noam Kadouri, Osher Ben-Nun, Amit Binyamin, Bar Lavi, Tal Givony, Razi Khalaila, Tom Gome, Tomáš Wald, Blanka Mrazkova, Carmel Sochen, Marine Besnard, Shifra Ben-Dor, Ester Feldmesser, Elisaveta M Orlova, Csaba Hegedűs, István Lampé, Tamás Papp, Szabolcs Felszeghy, Radislav Sedlacek, Esti Davidovich, Noa Tal, Dror S Shouval, Raanan Shamir, Carole Guillonneau, Zsuzsa Szondy, Knut E A Lundin, Radim Osicka, Jan Prochazka, Eystein S Husebye, Jakub Abramson

Journal: Nature

PubMed ID: 37993717

Doi: 10.1038/s41586-023-06776-0

Products & Services: Proteins, Expression, Isolation and Analysis

Mechanism of δ Mediated Transcription Activation in Bacillus subtilis: Interaction with α CTD of RNA Polymerase Stabilizes δ and Successively Facilitates the Open Complex Formation

Authors: Aniruddha Tewary, Ranjit Kumar Prajapati, Jayanta Mukhopadhyay

Journal: J Mol Biol

PubMed ID: 37972688

Doi: 10.1016/j.jmb.2023.168366

Products & Services: Proteins, Expression, Isolation and Analysis

RNA is a key component of extracellular DNA networks in Pseudomonas aeruginosa biofilms

Authors: Sudarsan Mugunthan, Lan Li Wong, Fernaldo Richtia Winnerdy, Stephen Summers, Muhammad Hafiz Bin Ismail, Yong Hwee Foo, Tavleen Kaur Jaggi, Oliver W Meldrum, Pei Yee Tiew, Sanjay H Chotirmall, Scott A Rice, Anh Tuân Phan, Staffan Kjelleberg, Thomas Seviour

Journal: Nat Commun

PubMed ID: 38012164

Doi: 10.1038/s41467-023-43533-3

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Effects of protoscoleces excretory-secretory products of Echinococcus granulosus on hepatocyte growth, function, and glucose metabolism

Authors: Guangyi Luo, Haiwen Li, Qiong Lu, Jiangtao Cao, Hailong Lv, Yufeng Jiang

Journal: Acta Trop

PubMed ID: 37944837

Doi: 10.1016/j.actatropica.2023.107066

Products & Services: Molecular Biology Reagents

Ana Castillo Discusses Sexuality, Identity, and Life-Then and Now

Authors: Liliana C Gonzalez, Stacy I Macias

Journal: J Lesbian Stud

PubMed ID: 37791458

Doi: 10.1080/10894160.2023.2250670

Products & Services: Plasmid DNA Preparation

Diurnal regulation of alternative splicing associated with thermotolerance in rice by two glycine-rich RNA-binding proteins

Authors: Chuang Yang, Anni Luo, Hai-Ping Lu, Seth Jon Davis, Jian-Xiang Liu

Journal: Sci Bull (Beijing)

PubMed ID: 38044192

Doi: 10.1016/j.scib.2023.11.046

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2

Authors: Shengnan Zhu, Qingning Yuan, Xinzhu Li, Xinheng He, Shiyi Shen, Dongxue Wang, Junrui Li, Xi Cheng, Xiaoqun Duan, H Eric Xu, Jia Duan

Journal: Cell Rep

PubMed ID: 37952153

Doi: 10.1016/j.celrep.2023.113406

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Non-canonical MLL1 activity regulates centromeric phase separation and genome stability

Authors: Liang Sha, Zi Yang, Sojin An, Wentao Yang, Sungmin Kim, Hoon Oh, Jing Xu, Jun Yin, He Wang, Heinz-Josef Lenz, Woojin An, Uhn-Soo Cho, Yali Dou

Journal: Nat Cell Biol

PubMed ID: 37945831

Doi: 10.1038/s41556-023-01270-1

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ZNF70 regulates IL-1β secretion of macrophages to promote the proliferation of HCT116 cells via activation of NLRP3 inflammasome and STAT3 pathway in colitis-associated colorectal cancer

Authors: Zhihong Zhang, Mingyue Li, Yi Tai, Yue Xing, Hongxiang Zuo, Xuejun Jin, Juan Ma

Journal: Cell Signal

PubMed ID: 38000525

Doi: 10.1016/j.cellsig.2023.110979

Products & Services: Molecular Biology Reagents

Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding

Authors: Zhi Li , Ning Wu , Jing Wang , Yang Yue , Lihua Geng , Quanbin Zhang

Journal: Br J Pharmacol .

PubMed ID: 37994102

Doi: 10.1111/bph.16288

Products & Services: Proteins, Expression, Isolation and Analysis

Chimeric Antigen Receptor T Cell Therapy Targeting Epithelial Cell Adhesion Molecule in Gastric Cancer: Mechanisms of Tumor Resistance

Authors: Yanping Yang, Raymond Louie, Janusz Puc, Yogindra Vedvyas, Yago Alcaina, Irene M Min, Matt Britz, Fabio Luciani, Moonsoo M Jin

Journal: Cancers (Basel)

PubMed ID: 38067255

Doi: 10.3390/cancers15235552

Products & Services: Proteins, Expression, Isolation and Analysis

Regulation of Atg8 membrane deconjugation by cysteine proteases in the malaria parasite Plasmodium berghei

Authors: Akancha Mishra, Aastha Varshney, Satish Mishra

Journal: Cell Mol Life Sci

PubMed ID: 37910326

Doi: 10.1007/s00018-023-05004-2

Products & Services: Peptide Synthesis

Enhancing the Physicochemical Attributes of Dough and Noodles through the Incorporation of Laccase

Authors: Xiaoyu Zhu, Shijin Zhang, Luyao Bian, Juan Shen, Chong Zhang, Sivakumar Manickam, Yang Tao, Zhaoxin Lu

Journal: Foods

PubMed ID: 38002203

Doi: 10.3390/foods12224146

Products & Services: Proteins, Expression, Isolation and Analysis

Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51

Authors: Lei Tao, Yue Zhou, Xiangyu Pan, Yuan Luo, Jiahao Qiu, Xia Zhou, Zhiqian Chen, Yan Li, Lian Xu, Yang Zhou, Zeping Zuo, Chunqi Liu, Liang Wang, Xiaocong Liu, Xinyu Tian, Na Su, Zhengnan Yang, Yu Zhang, Kun Gou, Na Sang, Huan Liu, Jiao Zou, Yuzhou Xiao, Xi Zhong, Jing Xu, Xinyu Yang, Kai Xiao, Yanyang Liu, Shengyong Yang, Yong Peng, Junhong Han, Xiaobo Cen, Yinglan Zhao

Journal: Nat Commun

PubMed ID: 37973845

Doi: 10.1038/s41467-023-42850-x

Products & Services: Molecular Biology Reagents

Author Correction: A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques

Authors: Ting Bian, Meng Hao, Xiaofan Zhao, Chuanyi Zhao, Gang Luo, Zhendong Zhang, Guangcheng Fu, Lu Yang, Yi Chen, Yudong Wang, Changming Yu, Yilong Yang, Jianmin Li, Wei Chen

Journal: npj Vaccines

PubMed ID: 38017028

Doi: 10.1038/s41541-023-00780-1

Products & Services: Proteins, Expression, Isolation and Analysis

Inflammation primes the kidney for recovery by activating AZIN1 A-to-I editing

Authors: Segewkal Heruye, Jered Myslinski, Chao Zeng, Amy Zollman, Shinichi Makino, Azuma Nanamatsu, Quoseena Mir, Sarath Chandra Janga, Emma H Doud, Michael T Eadon, Bernhard Maier, Michiaki Hamada, Tuan M Tran, Pierre C Dagher, Takashi Hato

Journal: biorxiv

PubMed ID: 37986799

Doi: 10.1101/2023.11.09.566426

Products & Services: Gene Synthesis

Dual function of Zika virus NS2B-NS3 protease

Authors: Sergey A Shiryaev, Piotr Cieplak, Anton Cheltsov, Robert C Liddington, Alexey V Terskikh

Journal: PLoS Pathog

PubMed ID: 38011215

Doi: 10.1371/journal.ppat.1011795

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Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid

Authors: Sílvia Àvila-Cabré, Míriam Pérez-Trujillo, Joan Albiol, Pau Ferrer

Journal: Microb Cell Fact

PubMed ID: 37978380

Doi: 10.1186/s12934-023-02241-9

Products & Services: Proteins, Expression, Isolation and Analysis

Comparison of biliary protein spectrum in gallstone patients with obesity and those with normal body weight

Authors: Min-Zhi Chen, Ping Xie, Xiao-Chang Wu, Zhen-Hua Tan, Hai Qian, Zhi-Hong Ma, Xing Yao

Journal: Hepatobiliary Pancreat Dis Int

PubMed ID: 38040523

Doi: 10.1016/j.hbpd.2023.11.007

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A Subunit Vaccine Candidate Composed of Mpox Virus A29L, M1R, A35R, and B6R Elicits Robust Immune Response in Mice

Authors: Xuetao Yang , Xidan Yang , Shouwen Du , Congxia Hu , Xiu Yang , Xingyun Wang , Xing Hu , Nino Rcheulishvili , Peng George Wang and Jihui Lin

Journal: Vaccines.

Doi: 10.3390/vaccines11091420

Products & Services: Gene Synthesis

Fluorescence-quenching lateral flow immunoassay for “turn-on” and sensitive detection of anti-SARS-CoV-2 neutralizing antibodies in human serum

Authors: Lun Bian , Qiangqiang Fu , Zhuoheng Gan , Ze Wu , Yuchen Song , Yufeng Xiong , Fang Hu, Lei Zheng

Journal: Adv Sci (Weinh) .

PubMed ID: 38032112

Doi: 10.1002/advs.202305774

Products & Services: Recombinant Proteins

Functional Characterization of Novel Variants Identified in Two Unrelated Patients with Morbid Obesity in Qatar

Authors: Idris Mohammed, Senthil Selvaraj, Wesam S Ahmed, Tara Al-Barazenji, Ayat S Hammad, Hajar Dauleh, Luis R Saraiva, Mashael Al-Shafai, Khalid Hussain

Journal: Int J Mol Sci

PubMed ID: 38003551

Doi: 10.3390/ijms242216361

Products & Services: Proteins, Expression, Isolation and Analysis

Validation of a highly sensitive HaloTag-based assay to evaluate the potency of a novel class of allosteric β-Galactosidase correctors

Authors: Mikhail Rudinskiy, Maria Pons-Vizcarra, Tatiana Soldà, Ilaria Fregno, Timothy Jan Bergmann, Ana Ruano, Aida Delgado, Sara Morales, Xavier Barril, Manolo Bellotto, Elena Cubero, Ana María García-Collazo, Natalia Pérez-Carmona, Maurizio Molinari

Journal: PLoS ONE

PubMed ID: 38019733

Doi: 10.1371/journal.pone.0294437

Products & Services: Proteins, Expression, Isolation and Analysis

Galectin-14 promotes hepatocellular carcinoma tumor growth enhancing heparan sulfate proteoglycan modification

Authors: Liming Gou, Gang Yang, Sujuan Ma, Tong Ding, Luan Sun, Fang Liu, Jin Huang, Wei Gao

Journal: J Biomed Res

PubMed ID: 37977559

Doi: 10.7555/JBR.37.20230085

Products & Services: Proteins, Expression, Isolation and Analysis

EBF2 Links KMT2D-Mediated H3K4me1 to Suppress Pancreatic Cancer Progression via Upregulating KLLN

Authors: Bing Yao, Mengying Xing, Shixin Meng, Shang Li, Jingwan Zhou, Ming Zhang, Chen Yang, Shuang Qu, Yucui Jin, Hongyan Yuan, Ke Zen, Changyan Ma

Journal: Adv Sci (Weinh)

PubMed ID: 38015024

Doi: 10.1002/advs.202302037

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A nanoparticle vaccine displaying the ookinete PSOP25 antigen elicits transmission-blocking antibody response against Plasmodium berghei

Authors: Guixiang Yao, Hui Min, Xinxin Yu, Fei Liu, Liwang Cui, Yaming Cao

Journal: Parasit Vectors

PubMed ID: 37932796

Doi: 10.1186/s13071-023-06020-8

Products & Services: Proteins, Expression, Isolation and Analysis

Suburban Population of Bobcats (Lynx rufus) in Connecticut, USA, Tested Negative for SARS-CoV-2, November 2021-February 2022

Authors: Maureen Sims, Zeinab Helal, Milton Levin, Tracy Rittenhouse, Jason Hawley, Guillermo R Risatti

Journal: J Wildl Dis

PubMed ID: 37924242

Doi: 10.7589/JWD-D-23-00054

Products & Services: Proteins, Expression, Isolation and Analysis

Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective against Omicron

Authors: Daniela Bottero, Erika Rudi, Pablo Martin Aispuro, Eugenia Zurita, Emilia Gaillard, Maria M Gonzalez Lopez Ledesma, Juan Malito, Matthew Stuible, Nicolas Ambrosis, Yves Durocher, Andrea V Gamarnik, Andrés Wigdorovitz, Daniela Hozbor

Journal: Front Immunol

PubMed ID: 38022542

Doi: 10.3389/fimmu.2023.1271209

Products & Services: Proteins, Expression, Isolation and Analysis

Dynamics of Serum-Neutralizing Antibody Responses in Vaccinees through Multiple Doses of the BNT162b2 Vaccine

Authors: Jared Sheehan, Caleb M Ardizzone, Mayank Khanna, Amber J Trauth, Michael E Hagensee, Alistair J Ramsay

Journal: Vaccines (Basel)

PubMed ID: 38006052

Doi: 10.3390/vaccines11111720

Products & Services: Gene Synthesis

Cytoplasmic production of Fabs in chemically defined media in fed-batch fermentation

Authors: Angel Castillo-Corujo, Mirva J Saaranen, Lloyd W Ruddock

Journal: Protein Expr Purif

PubMed ID: 37979630

Doi: 10.1016/j.pep.2023.106404

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular Analysis of a Congenital Myasthenic Syndrome Due to a Pathogenic Variant Affecting the C-Terminus of ColQ

Authors: Susie Barbeau, Fannie Semprez, Alexandre Dobbertin, Laurine Merriadec, Florine Roussange, Bruno Eymard, Damien Sternberg, Emmanuel Fournier, Hanice Karasoy, Cécile Martinat, Claire Legay

Journal: Int J Mol Sci

PubMed ID: 38003406

Doi: 10.3390/ijms242216217

Products & Services: Gene Synthesis

Interplay between stochastic enzyme activity and microtubule stability drives detyrosination enrichment on microtubule subsets

Authors: Qing Tang, Sebastian Sensale, Charles Bond, Jiazheng Xing, Andy Qiao, Siewert Hugelier, Arian Arab, Gaurav Arya, Melike Lakadamyali

Journal: Curr Biol

PubMed ID: 37979580

Doi: 10.1016/j.cub.2023.10.068

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