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A Plasmodium apicoplast-targeted unique exonuclease/FEN exhibits interspecies functional differences attributable to an insertion that alters DNA-binding
Authors: Tribeni Chatterjee, Anupama Tiwari, Ritika Gupta, Himadri Shukla, Aastha Varshney, Satish Mishra, Saman Habib
Journal: Nucleic Acids Res
PubMed ID: 38888125
Doi: 10.1093/nar/gkae512
Products & Services: Gene Synthesis   
Optimization of dilution rate and mixed carbon feed for continuous production of recombinant plant sucrose:sucrose 1-fructosyltransferase in Komagataella phaffii
Authors: Avijeet S Jaswal, Ravikrishnan Elangovan, Saroj Mishra
Journal: Bioprocess Biosyst Eng
PubMed ID: 38904715
Doi: 10.1007/s00449-024-03045-w
Products & Services: PCR Cloning and Subcloning   
CoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels
Authors: Yin Liu, Xinyi Liu, Dongyi Wei, Lu Dang, Xiaoran Xu, Shisheng Huang, Liwen Li, Sanyun Wu, Jinxian Wu, Xiaoyan Liu, Wenjun Sun, Wanyu Tao, Yongchang Wei, Xingxu Huang, Kui Li, Xinjie Wang, Fuling Zhou
Journal: Nat Commun
PubMed ID: 38866774
Doi: 10.1038/s41467-024-49414-7
Products & Services: Gene Synthesis   
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria
Authors: Hunter L Abrahamsen, Tristan C Sanford, Casie E Collamore, Bronte A Johnstone, Michael J Coyne, Leonor García-Bayona, Michelle P Christie, Jordan C Evans, Allison J Farrand, Katia Flores, Craig J Morton, Michael W Parker, Laurie E Comstock, Rodney K Tweten
Journal: Nat Commun
PubMed ID: 38866748
Doi: 10.1038/s41467-024-49103-5
Products & Services: Recombinant Proteins   
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2-STAT3 pathway
Authors: Jiahua Yang, Xuechuan Li, Shili Chen, Guoqiang Li, Peng Pu, Yang Yang, Wenguang Wu, Yajun Geng, Yingbin Liu
Journal: Cancer Lett
PubMed ID: 38942137
Doi: 10.1016/j.canlet.2024.217067
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Mechanism and spectrum of inhibition of a 4´-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses
Authors: Calvin J Gordon, Simon M Walker, Egor P Tchesnokov, Dana Kocincova, Jared Pitts, Dustin S Siegel, Jason K Perry, Joy Y Feng, John P Bilello, Matthias Götte
Journal: J Biol Chem
PubMed ID: 38945449
Doi: 10.1016/j.jbc.2024.107514
Products & Services: Molecular Biology Reagents   
Recombinant Art v401 protein produces immunological tolerance by subcutaneous immunotherapy in a wormwood pollen-driven allergic asthma female mouse model
Authors: Tao Wang, Jiaoni Chi, Zhimin Li, Yue Zhang, Yaojun Wang, Ming Ding, Bin Zhou, JiaChen Gui, Qiang Li
Journal: PLoS ONE
PubMed ID: 38941291
Doi: 10.1371/journal.pone.0280418
Products & Services: Molecular Biology Reagents   
Single missense mutations in Vi capsule synthesis genes confer hypervirulence to Salmonella Typhi
Authors: Gi Young Lee, Jeongmin Song
Journal: Nat Commun
PubMed ID: 38898034
Doi: 10.1038/s41467-024-49590-6
Products & Services: Recombinant Proteins   
IMT030122, A novel engineered EpCAM/CD3/4-1BB tri-specific antibody, enhances T-cell recruitment and demonstrates anti-tumor activity in mouse models of colorectal cancer
Authors: Jianbo Shen, Niliang Qian, Guili Xu, Xiaoqian Dou, Ying An, Cuima Yang, Yujie Liu, Yunhui Liu, Xiujie Pan, Jingjing Wang, Guijun Bai, Hao Chen, Xiaolin Zhu, Xin Gao, Guoxiong Zhou, Qinzhi Xu
Journal: Int Immunopharmacol
PubMed ID: 38878486
Doi: 10.1016/j.intimp.2024.112424
Products & Services: Protein and Antibody Isolation   
Monoterpene-chalcone conjugates and diarylheptanoids isolated from the seeds of Alpinia katsumadai Hayata with cytotoxic activity
Authors: Hua-Lin You, Bo Zhou, Meng-Jia Guo, Xin-Man Zhao, Xiao-Long Li, Xiang-Chun Shen, Nen-Ling Zhang
Journal: Phytochemistry
PubMed ID: 38945281
Doi: 10.1016/j.phytochem.2024.114197
Products & Services: PCR Cloning and Subcloning   
Plasmodium vivax serological exposure markers: PvMSP1-42-induced humoral and memory B-cell response generates long-lived antibodies
Authors: Feng Lu, Jiahui Xu, Yaobao Liu, Zhenyu Ren, Junhu Chen, Weijuan Gong, Yi Yin, Yinyue Li, Li Qian, Xinlong He, Xiu Han, Zhijie Lin, Jingyuan Lu, Wenwen Zhang, Jiali Liu, Didier Menard, Eun-Taek Han, Jun Cao
Journal: PLoS Pathog
PubMed ID: 38941356
Doi: 10.1371/journal.ppat.1012334
Products & Services: Protein and Antibody Isolation   
SepM mutation in Streptococcus mutans clinical isolates and related function analysis
Authors: Shanshan Liu, Yidan Shao, Zhenzhen Zhang, Wen Xu, Yudong Liu, Kai Zhang, Li Xu, Qingwei Zheng, Yu Sun
Journal: BMC Oral Health
PubMed ID: 38918777
Doi: 10.1186/s12903-024-04436-x
Products & Services: Gene Synthesis   
OsNLP3 enhances grain weight and reduces grain chalkiness in rice
Authors: Liang-Qi Sun, Yu Bai, Jie Wu, Shi-Jun Fan, Si-Yan Chen, Zheng-Yi Zhang, Jin-Qiu Xia, Shi-Mei Wang, Yu-Ping Wang, Peng Qin, Shi-Gui Li, Ping Xu, Zhong Zhao, Cheng-Bin Xiang, Zi-Sheng Zhang
Journal: Plant Commun
PubMed ID: 38853433
Doi: 10.1016/j.xplc.2024.100999
Products & Services: Recombinant Proteins   
M tuberculosis PrrA binds the dosR promoter and regulates mycobacterial adaptation to hypoxia
Authors: Yannik A Haller, Jiapei Jiang, Zijian Wan, Alexia Childress, Shaopeng Wang, Shelley E Haydel
Journal: Tuberculosis (Edinb)
PubMed ID: 38885567
Doi: 10.1016/j.tube.2024.102531
Products & Services: Custom Vector Construction   
The Gene Network That Regulates Head Organizer Activity in Is Differentially Regulated in Epidermis and Gastrodermis
Authors: Laura Iglesias Ollé, Chrystelle Perruchoud, Paul Gerald Layague Sanchez, Matthias Christian Vogg, Brigitte Galliot
Journal: Biomedicines
PubMed ID: 38927481
Doi: 10.3390/biomedicines12061274
Products & Services: DNA Sequencing   
Immuno-Microbial Signature of Vaccine-Induced Immunity against SARS-CoV-2
Authors: Lesley Umeda, Amada Torres, Braden P Kunihiro, Noelle C Rubas, Riley K Wells, Krit Phankitnirundorn, Rafael Peres, Ruben Juarez, Alika K Maunakea
Journal: Vaccines (Basel)
PubMed ID: 38932366
Doi: 10.3390/vaccines12060637
Products & Services: Gene Synthesis   
An optimized and robust workflow for quantifying the canonical histone ubiquitination marks H2AK119ub and H2BK120ub by LC-MS/MS
Authors: Mariana Lopes, Peder J Lund, Benjamin A Garcia
Journal: biorxiv
PubMed ID: 38915586
Doi: 10.1101/2024.06.11.596744
Products & Services: Catalog Peptides   
Identification of a human type XVII collagen fragment with high capacity for maintaining skin health
Authors: Xinglong Wang, Shuyao Yu, Ruoxi Sun, Kangjie Xu, Kun Wang, Ruiyan Wang, Junli Zhang, Wenwen Tao, Shangyang Yu, Kai Linghu, Xinyi Zhao, Jingwen Zhou
Journal: Synth Syst Biotechnol
PubMed ID: 38911060
Doi: 10.1016/j.synbio.2024.06.001
Products & Services: Gene Synthesis   
A novel BSL-2 Lassa virus reverse genetics system modelling the complete viral life cycle
Authors: Xiaoyou Hu, Xu Bai, Fangling Tian, Yifan Xing, Yi Shi, Yimin Tong, Jin Zhong
Journal: Emerg Microbes Infect
PubMed ID: 38747061
Doi: 10.1080/22221751.2024.2356149
Distance tuneable integral membrane protein containing floating bilayers directed self-assembly
Authors: Stephen C L Hall, David J Hardy, Éilís C Bragginton, Hannah Johnston, Tudor Onose, Rachel Holyfield, Pooja Sridhar, Timothy J Knowles, Luke A Clifton
Journal: Nanoscale
PubMed ID: 38940744
Doi: 10.1039/d3nr04622b
Products & Services: Protein and Antibody Isolation   
Metabolic Engineering of for Production of Canthaxanthin, Zeaxanthin, and Astaxanthin
Authors: Peerada Promdonkoy, Akaraphol Watcharawipas, Suriyaporn Bubphasawan, Kitisak Sansatchanon, Nattida Suwanakitti, Kanokarn Kocharin, Weerawat Runguphan
Journal: J Fungi (Basel)
PubMed ID: 38921419
Doi: 10.3390/jof10060433
Products & Services: Codon Optimization   
A 14-amino acid cationic peptide Bolespleenin from the marine fish mudskipper Boleophthalmus pectinirostris exhibiting potent antimicrobial activity and therapeutic potential
Authors: Yuqi Bai, Weibin Zhang, Wenbin Zheng, Xin-Zhan Meng, Yingyi Duan, Chang Zhang, Fangyi Chen, Ke-Jian Wang
Journal: Biochem Pharmacol
PubMed ID: 38852647
Doi: 10.1016/j.bcp.2024.116344
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Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy
Authors: Vadim A Klenchin, Natasha M Clark, Nida K Keles, Saverio Capuano, Rosemarie Mason, Guangping Gao, Aimee Broman, Emek Kose, Taina T Immonen, Christine M Fennessey, Brandon F Keele, Jeffrey D Lifson, Mario Roederer, Matthew R Gardner, David T Evans
Journal: biorxiv
PubMed ID: 38895320
Doi: 10.1101/2024.05.30.593694
Products & Services: Codon Optimization   
The role of MASP1 in the complement system and expression characteristics in response to GCRV infection in grass carp
Authors: Yuling Wei, Zhao Lv, Tiaoyi Xiao, Zongjun Du
Journal: Fish Shellfish Immunol
PubMed ID: 38901682
Doi: 10.1016/j.fsi.2024.109712
Products & Services: Protein and Antibody Isolation   
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein
Authors: Qi Yang, Bao Xue, Fengjiang Liu, Yongzhi Lu, Jielin Tang, Mengrong Yan, Qiong Wu, Ruyi Chen, Anqi Zhou, Lijie Liu, Junjun Liu, Changbin Qu, Qingxin Wu, Muqing Fu, Jiayi Zhong, Jianwei Dong, Sijie Chen, Fan Wang, Yuan Zhou, Jie Zheng, Wei Peng, Jinsai Shang, Xinwen Chen
Journal: Signal Transduct Target Ther
PubMed ID: 38853183
Doi: 10.1038/s41392-024-01858-5
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Exploring AlphaFold2 s Performance on Predicting Amino Acid Side-Chain Conformations and Its Utility in Crystal Structure Determination of B318L Protein
Authors: Haifan Zhao; Heng Zhang; Zhun She; Zengqiang Gao; Qi Wang; Zhi Geng; Yuhui Dong
Journal: International Journal of Molecular Sciences
PubMed ID: 36769074
Doi: 10.3390/ijms24032740
Exploring AlphaFold2 s Performance on Predicting Amino Acid Side-Chain Conformations and Its Utility in Crystal Structure Determination of B318L Protein
Authors: Haifan Zhao; Heng Zhang; Zhun She; Zengqiang Gao; Qi Wang; Zhi Geng; Yuhui Dong
Journal: International Journal of Molecular Sciences
PubMed ID: 36769074
Doi: 10.3390/ijms24032740
PAM-flexible Engineered FnCas9 variants for robust and ultra-precise genome editing and diagnostics
Authors: Sundaram Acharya, Asgar Hussain Ansari, Prosad Kumar Das, Seiichi Hirano, Meghali Aich, Riya Rauthan, Sudipta Mahato, Savitri Maddileti, Sajal Sarkar, Manoj Kumar, Rhythm Phutela, Sneha Gulati, Abdul Rahman, Arushi Goel, C Afzal, Deepanjan Paul, Trupti Agrawal, Vinay Kumar Pulimamidi, Subhadra Jalali, Hiroshi Nishimasu, Indumathi Mariappan, Osamu Nureki, Souvik Maiti, Debojyoti Chakraborty
Journal: Nat Commun
PubMed ID: 38942756
Doi: 10.1038/s41467-024-49233-w
Products & Services: Gene Synthesis   
Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity
Authors: Siddhi Omkar, Courtney Shrader, Joel R Hoskins, Jake T Kline, Megan M Mitchem, Luca Fornelli, Sue Wickner, Andrew W Truman
Journal: biorxiv
PubMed ID: 38915721
Doi: 10.1101/2024.06.13.598777
Products & Services: Molecular Biology Reagents   
miR-520e and its promoter region DNA methylation as potential biomarkers in atherosclerosis
Authors: Mimi Mu, Gao Liu, Xiaoyu Ding, Lijun Xue, Dandan Li, Yunhua Zhu, Nan Zhang, Jia Wu, Junjun Wang
Journal: Biochem Cell Biol
PubMed ID: 38917487
Doi: 10.1139/bcb-2023-0326
Products & Services: Molecular Biology Reagents   
Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels
Authors: Emily Mantlo, Jessie D Trujillo, Natasha N Gaudreault, Igor Morozov, Charles E Lewis, Franco Matias-Ferreyra, Chester McDowell, Dashzeveg Bold, Taeyong Kwon, Konner Cool, Velmurugan Balaraman, Daniel Madden, Bianca Artiaga, Jayme Souza-Neto, Jeffrey B Doty, Mariano Carossino, Udeni Balasuriya, William C Wilson, Nikolaus Osterrieder, Lisa Hensley, Juergen A Richt
Journal: Emerg Microbes Infect
PubMed ID: 38712637
Doi: 10.1080/22221751.2024.2352434
Products & Services: PCR Cloning and Subcloning   
Effect of TIMPs and Their Minimally Engineered Variants in Blocking Invasion and Migration of Brain Cancer Cells
Authors: Elham Taheri, Maryam Raeeszadeh-Sarmazdeh
Journal: biorxiv
PubMed ID: 38895489
Doi: 10.1101/2024.06.05.597644
Products & Services: Catalog Peptides   
H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs
Authors: Fei-Fei Ge, Li-Pin Shen, De-Quan Yang, Xian-Cao Yang, Xin Li, Hai-Xiao Shen, Jian Wang, Shixin Huang
Journal: Microbiol Spectr
PubMed ID: 38874403
Doi: 10.1128/spectrum.00445-24
Products & Services: Gene Synthesis   
Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in
Authors: Marcus Foo, Luke R Frietze, Behnam Enghiad, Yujie Yuan, Christopher D Katanski, Huimin Zhao, Tao Pan
Journal: ACS Chem Biol
PubMed ID: 38912606
Doi: 10.1021/acschembio.4c00278
Products & Services: Gene Synthesis   
Identification of a novel glycoside hydrolase family 8 xylanase from Deinococcus geothermalis and its application at low temperatures
Authors: Tingting Wang, Min Lin, Yongliang Yan, Shijie Jiang, Qilin Dai, Zhengfu Zhou, Jin Wang
Journal: Arch Microbiol
PubMed ID: 38884653
Doi: 10.1007/s00203-024-04055-8
Products & Services: Protein and Antibody Isolation   
Transgenic Soybean for Production of Thermostable α-Amylase
Authors: Zhenyan Cao, Ye Jiang, Jiajie Li, Ting Zheng, Chaoyang Lin, Zhicheng Shen
Journal: Plants (Basel)
PubMed ID: 38891347
Doi: 10.3390/plants13111539
Products & Services: Recombinant Proteins   
Scaffold-enabled high-resolution cryo-EM structure determination of RNA
Authors: Daniel B Haack, Boris Rudolfs, Shouhong Jin, Kevin M Weeks, Navtej Toor
Journal: biorxiv
PubMed ID: 38915706
Doi: 10.1101/2024.06.10.598011
Products & Services: Molecular Biology Reagents   
Arboviruses antagonize insect Toll antiviral immune signaling to facilitate the coexistence of viruses with their vectors
Authors: Dongsheng Jia, Guozhong Luo, Heran Guan, Tingting Yu, Xinyan Sun, Yu Du, Yiheng Wang, Hongyan Chen, Taiyun Wei
Journal: PLoS Pathog
PubMed ID: 38865374
Doi: 10.1371/journal.ppat.1012318
Products & Services: Polyclonal Antibody Services   
Heterologous booster vaccination enhances antibody responses to SARS-CoV-2 by improving Tfh function and increasing B-cell clonotype SHM frequency
Authors: Yanli Song, Jiaolei Wang, Zhihui Yang, Changgui Li
Journal: Frontiers in Immunology
Doi: 10.3389/fimmu.2024.1406138
Products & Services: Catalog Peptides   
Tight Junction Component Occludin Binds to FIP5 to Regulate Endosome Trafficking and Mitotic Spindle Function
Authors: Zichao Zhang , Jing Chen , Rongze Ma , Chongshen Xu , Yunzhe Lu , Jiecan Zhou , Kun Xia , Pengfei Lu
Journal: Adv Sci (Weinh)
PubMed ID: 38884279
Doi: 10.1002/advs.202308822
Products & Services: Recombinant Proteins   
A bispecific antibody exhibits broad neutralization against SARS-CoV-2 Omicron variants XBB.1.16, BQ.1.1 and sarbecoviruses
Authors: Yingdan Wang # 1 2, Aihua Hao # 1, Ping Ji # 1, Yunping Ma # 1 3, Zhaoyong Zhang # 4, Jiali Chen 1, Qiyu Mao 1, Xinyi Xiong 4, Palizhati Rehati 1, Yajie Wang 1, Yanqun Wang 4, Yumei Wen 1, Lu Lu 1, Zhenguo Chen 1, Jincun Zhao 5 6, Fan Wu 7, Jinghe Huang 8 9, Lei Sun 10
Journal: Nat Commun
PubMed ID: 38879565
Doi: 10.1038/s41467-024-49096-1
Products & Services: Gene Synthesis   
Molecular recognition of the atypical chemokine-like peptide GPR15L by its cognate receptor GPR15
Authors: Zhongyuan Zhang , You Zheng , Lu Xu , Yang Yue , Kexin Xu , Fei Li 1, Fei Xu
Journal: Cell Discov
PubMed ID: 38918398
Doi: 10.1038/s41421-024-00698-5
Products & Services: Peptide Synthesis   
The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer
Authors: Pengfei Yan , Xi Lin , Lijie Wu , Lu Xu , Fei Li , Junlin Liu , Fei Xu
Journal: Nat Commun
PubMed ID: 38898050
Doi: 10.1038/s41467-024-49625-y
Products & Services: Gene Synthesis   
Auxin resistant 2 and short hypocotyl 2 regulate cotton fiber initiation and elongation
Authors: Fei Jin, Liping Zhu, Liyong Hou, Hongbin Li, Ling Li, Guanghui Xiao
Journal: Plant Physiol
PubMed ID: 38527791
Doi: 10.1093/plphys/kiae183
Products & Services: Protein and Antibody Isolation   
Interleukin-1 beta (IL-1β) as adjuvant enhances the immune effects of Aeromonas veronii inactivated vaccine in largemouth bass (Micropterus salmoides)
Authors: Ze-Sheng Zhang, Heng-Chu Ren, Xie Gu, Qian-Rong Liang, Hui Fei, Yu-Hong Yang, Shun Yang, Liang-Yin He, Li-Li Liu
Journal: Int J Biol Macromol
PubMed ID: 38876231
Doi: 10.1016/j.ijbiomac.2024.133135
Products & Services: Molecular Biology Reagents   
Development of GPC3-CAR-NK cells and optimization as a therapy for HCC
Authors: Bihui Cao, Qianqian Ni, Zhuxin Chen, Shuo Yang, Xinkui Zhang, Haotao Su, Zhenfeng Zhang, Qi Zhao, Xiaolan Zhu, Manting Liu
Journal: J Leukoc Biol
PubMed ID: 38922297
Doi: 10.1093/jleuko/qiae144
Products & Services: Molecular Biology Reagents   
Androgen-responsive FOXP4 is a target for endometrial carcinoma
Authors: Kayo Kayahashi, Mahadi Hasan, Anowara Khatun, Susumu Kohno, Jumpei Terakawa, Shin-Ichi Horike, Natsumi Toyoda, Ayumi Matsuoka, Takashi Iizuka, Takeshi Obata, Masanori Ono, Yasunari Mizumoto, Chiaki Takahashi, Hiroshi Fujiwara, Takiko Daikoku
Journal: Commun Biol
PubMed ID: 38890503
Doi: 10.1038/s42003-024-06433-w
Products & Services: Molecular Biology Reagents   
Molecular determinants of olfactory receptor activation: Comparative analysis of Olfr205 and Olfr740 family member responses to indole
Authors: Guangyao Li, Li Wang, Fangzhou Ye, Shengju Li, Hongmeng Yu
Journal: Arch Biochem Biophys
PubMed ID: 38880319
Doi: 10.1016/j.abb.2024.110061
Products & Services: Molecular Biology Reagents   
Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering
Authors: Mona Alharbi, Andrew Lai, Nihar Godbole, Dominic Guanzon, Soumyalekshmi Nair, Felipe Zuñiga, Alexander Quinn, Mengliu Yang, Sherry Y Wu, Carlos Salomon
Journal: Int J Cancer
PubMed ID: 38848494
Doi: 10.1002/ijc.35055
Products & Services: Molecular Biology Reagents   
Selenium nanoparticles enhance mucosal immunity against Mycobacterium bovis infection
Authors: Xin Ge, Zhengmin Liang, Kui Li, Yuhui Dong, Yuanzhi Wang, Yiduo Liu, ZiYi Liu, Haoran Wang, Yue Nan, SiYan Chen, Lin Li, Yanbin Guo, Xiangmei Zhou
Journal: Int Immunopharmacol
PubMed ID: 38878484
Doi: 10.1016/j.intimp.2024.112384
Products & Services: Molecular Biology Reagents   
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