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ALOX5 deficiency contributes to bladder cancer progression by mediating ferroptosis escape

Authors: Tianyao Liu, Xinyan Xu, Jiazheng Li, Ming Bai, Wenjie Zhu, Yanqing Liu, Siyang Liu, Zihan Zhao, Tianhang Li, Ning Jiang, Yuhao Bai, Qingyang Jin, Yulin Zhang, Yufeng Zheng, Shengkai Zhou, Shoubin Zhan, Ying Sun, Gaoli Liang, Yang Luo, Xi Chen, Hongqian Guo, Rong Yang

Journal: Cell Death Dis

PubMed ID: 38062004

Doi: 10.1038/s41419-023-06333-7

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Bioinformatics analyses of infiltrating immune cell participation on pancreatic ductal adenocarcinoma progression and in vivo experiment of the therapeutic effect of Shuangshen granules

Authors: Jiaqi Hu, Juling Jiang, Bowen Xu, Yue Li, Bei Wang, Shulin He, Xiaoling Ren, Bolun Shi, Xing Zhang, Honggang Zheng, Baojin Hua, Rui Liu

Journal: J Ethnopharmacol

PubMed ID: 38113986

Doi: 10.1016/j.jep.2023.117590

Products & Services: Proteins, Expression, Isolation and Analysis

Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients

Authors: Jean-Pierre Bellier, Yuqi Cai, Sarah M Alam, Thorsten Wiederhold, Arica Aiello, Jonathan S Vogelgsang, Sabina Berretta, Jasmeer P Chhatwal, Dennis J Selkoe, Lei Liu

Journal: Alzheimers Dement

PubMed ID: 38041855

Doi: 10.1002/alz.13557

Products & Services: Proteins, Expression, Isolation and Analysis

Acid phosphatase-like proteins, a biogenic amine and leukotriene-binding salivary protein family from the flea Xenopsylla cheopis

Authors: Stephen Lu, John F Andersen, Christopher F Bosio, B Joseph Hinnebusch, José M Ribeiro

Journal: Commun Biol

PubMed ID: 38110569

Doi: 10.1038/s42003-023-05679-0

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Agonistic Bivalent Human scFvs-Fcγ Fusion Antibodies to OX40 Ectodomain Enhance T Cell Activities against Cancer

Authors: Kodchakorn Mahasongkram, Kantaphon Glab-Ampai, Kanasap Kaewchim, Thanatsaran Saenlom, Monrat Chulanetra, Nitat Sookrung, Oytip Nathalang, Wanpen Chaicumpa

Journal: Vaccines (Basel)

PubMed ID: 38140230

Doi: 10.3390/vaccines11121826

Products & Services: Recombinant Proteins

Emerging variants of SARS-CoV-2 NSP10 highlight strong functional conservation of its binding to two non-structural proteins, NSP14 and NSP16

Authors: Huan Wang, Syed R A Rizvi, Danni Dong, Jiaqi Lou, Qian Wang, Watanyoo Sopipong, Yufeng Su, Fares Najar, Pratul K Agarwal, Frank Kozielski, Shozeb Haider

Journal: Elife

PubMed ID: 38127066

Doi: 10.7554/eLife.87884

Products & Services: Proteins, Expression, Isolation and Analysis

The density of anionic lipids modulates the adsorption of α-Synuclein onto lipid membranes

Authors: Alexandra Andersson, Sara Linse, Emma Sparr, Marco Fornasier, Peter Jönsson

Journal: Biophys Chem

PubMed ID: 38100855

Doi: 10.1016/j.bpc.2023.107143

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Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis

Authors: Huixiang Ma, Tucan Chen, Chengxu Li, Hao Xu, Qingyu Feng, Yunfei Su, Jianqiu Cai, Qingfu Zhu, Fei Liu, Liang Hu

Journal: Ocul Surf

PubMed ID: 38122863

Doi: 10.1016/j.jtos.2023.12.005

Products & Services: Molecular Biology Reagents

Salidroside attenuates myocardial remodeling in DOCA-salt-induced mice by inhibiting the endothelin 1 and PI3K/AKT/NFκB signaling pathways

Authors: Qiao Liu, Qingman Luo, Bin Zhong, Kecheng Tang, Xueling Chen, Shengqian Yang, Xiaohui Li

Journal: Eur J Pharmacol

PubMed ID: 38048979

Doi: 10.1016/j.ejphar.2023.176236

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The egg ribonuclease SjCP1412 accelerates liver fibrosis caused by infection involving damage-associated molecular patterns (DAMPs)

Authors: Qi-Feng Li, Yi-Xin Li, Ying-Ying Yang, Pan-Pan Dong, Cong-Jin Mei, Ju-Lu Lu, Jian-Feng Zhang, Hai-Yong Hua, Chun-Rong Xiong, Chuan-Xin Yu, Li-Jun Song, Kun Yang

Journal: Parasitology

PubMed ID: 38105713

Doi: 10.1017/S0031182023001361

Products & Services: Molecular Biology Reagents

Immunogenicity Persistence of a Third-Dose Homologous BBIBP-CorV/CoronaVac Boosting Vaccination: A Prospective Open-Label Study

Authors: Na Ren, Zhihong Wang, Sikang Gao

Journal: Viral Immunol

PubMed ID: 38109058

Doi: 10.1089/vim.2023.0075

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Pro-osteogenic role of interleukin-22 in calcific aortic valve disease

Authors: Huifang Deng, Huadong Li, Zongtao Liu, Na Shen, Nianguo Dong, Cheng Deng, Fayuan Liu

Journal: Atherosclerosis

PubMed ID: 38104486

Doi: 10.1016/j.atherosclerosis.2023.117424

Products & Services: Proteins, Expression, Isolation and Analysis

Ferricyanide-promoted Oxidative Activation and Ligation of Protein Thioacids in Neutral Aqueous Media

Authors: Guo-Chao Chu, Lu-Jun Liang, Rui Zhao, Yan-Yan Guo, Chun-Tong Li, Chong Zuo, Huasong Ai, Xiao Hua, Zi-Chen Li, Yi-Ming Li, Lei Liu

Journal: CCS Chemistry

Doi: 10.31635/ccschem.023.202303397

Products & Services: Proteins, Expression, Isolation and Analysis

Immunoswitch Nanomodulators Enable Active Targeting and Selective Proliferation of Regulatory T Cells for Multiple Sclerosis Therapy

Authors: Xiaoshuang Wang , Zhilin Liu , Di Wang , Yingyu Zhang , Honglei Zhang , Fuxin Xue , Xianhong Wang , Zhaohui Tang , Xuemei Han

Journal: ACS Nano .

PubMed ID: 38113242

Doi: 10.1021/acsnano.3c09225

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In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma

Authors: Qiang Cheng, Lukas Farbiak, Amogh Vaidya, Erick Guerrero, Eunice E Lee, Elysha K Rose, Xu Wang, Joshua Robinson, Sang M Lee, Tuo Wei, William E Miller, Ester Alvarez Benedicto, Xizhen Lian, Richard C Wang, Daniel J Siegwart

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38109533

Doi: 10.1073/pnas.2313009120

Products & Services: Proteins, Expression, Isolation and Analysis

Suppression of overactive IGF-1 attenuates trauma-induced heterotopic ossification in mice

Authors: Dong Mao, Kai Wang, Hong Jiang, Jingyi Mi, Xiaoyun Pan, Gang Zhao, Yongjun Rui

Journal: Am J Pathol

PubMed ID: 38101566

Doi: 10.1016/j.ajpath.2023.11.012

Products & Services: Molecular Biology Reagents

The p30 protein of the African swine fever virus behaves as an RNase

Authors: Satyendu Nandy, Nilave Ranjan Bora, Shubham Gaurav, Sachin Kumar

Journal: Virology

PubMed ID: 38086285

Doi: 10.1016/j.virol.2023.109967

Products & Services: Molecular Biology Reagents

High levels of alpha-gal with large variation in the salivary glands of lone star ticks fed on human blood

Authors: L Paulina Maldonado-Ruiz, Kathryn E Reif, Anuradha Ghosh, Stephanie Foré, Rachel L Johnson, Yoonseong Park

Journal: Sci Rep

PubMed ID: 38049505

Doi: 10.1038/s41598-023-48437-2

Products & Services: Molecular Biology Reagents

Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides

Authors: Guillaume Gaud, Sooraj Achar, François X P Bourassa, John Davies, Teri Hatzihristidis, Seeyoung Choi, Taisuke Kondo, Selamawit Gossa, Jan Lee, Paul Juneau, Naomi Taylor, Christian S Hinrichs, Dorian B McGavern, Paul François, Grégoire Altan-Bonnet, Paul E Love

Journal: Nat Immunol

PubMed ID: 38057618

Doi: 10.1038/s41590-023-01725-5

Products & Services: Peptide Synthesis

Enhancing CAR-T cells: unleashing lasting impact potential with phytohemagglutinin activation in in vivo leukemia model

Authors: Berranur Sert, Gamze Gulden, Tarik Teymur, Yasin Ay, Raife Dilek Turan, Onur Mert Unaldi, Elanur Guzenge, Hamza Emir Erdil, Sevim Isik, Pinar Oz, Ilknur Bozkurt, Samed Ozer, Tahire Yurdakul, Osman Kamali, Ercument Ovali, Nevzat Tarhan, Cihan Tastan

Journal: Cancer Gene Ther

PubMed ID: 38092962

Doi: 10.1038/s41417-023-00709-9

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JH degradation pathway participates in hormonal regulation of larval development of Bombyx mori following λ-cyhalothrin exposure

Authors: Yue Su, Wanwan Wang, Yixin Dai, Ruinan Qi, Haoyi Gu, Xiqian Guo, Xinyu Liu, Yuying Ren, Fanchi Li, Bing Li, Haina Sun

Journal: Chemosphere

PubMed ID: 38056714

Doi: 10.1016/j.chemosphere.2023.140871

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Structural basis of branching during RNA splicing

Authors: Daniel B Haack, Boris Rudolfs, Cheng Zhang, Dmitry Lyumkis, Navtej Toor

Journal: Nat Struct Mol Biol

PubMed ID: 38057551

Doi: 10.1038/s41594-023-01150-0

Products & Services: Gene Synthesis

Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron-Specific Reactivity in a Vaccination Cohort

Authors: Michael Schoefbaenker, Rieke Neddermeyer, Theresa Guenther, Marlin M Mueller, Marie-Luise Romberg, Nica Classen, Marc T Hennies, Eike R Hrincius, Stephan Ludwig, Joachim E Kuehn, Eva U Lorentzen

Journal: Vaccines (Basel)

PubMed ID: 38140236

Doi: 10.3390/vaccines11121832

Products & Services: Plasmid DNA Preparation

tRF-1:30-Gly-CCC-3 inhibits thyroid cancer via binding to PC and modulating metabolic reprogramming

Authors: Bifei Fu, YuMing Lou, Xiaofeng Lu, Zhaolin Wu, Junjie Ni, Cong Jin, Pu Wu, Chaoyang Xu

Journal: Life Sci Alliance

PubMed ID: 38081642

Doi: 10.26508/lsa.202302285

Products & Services: Proteins, Expression, Isolation and Analysis

Chromosome recombination and modification by LoxP-mediated evolution in Vibrio natriegens using CRISPR-associated transposases

Authors: Jiaqi Xu, Yijie Sun, Jianping Wu, Sheng Yang, Lirong Yang

Journal: Biotechnol Bioeng

PubMed ID: 38131162

Doi: 10.1002/bit.28639

Products & Services: Gene Synthesis

A naturally occurring HA-stabilizing amino acid (HA1-Y17) in an A(H9N2) low-pathogenic influenza virus contributes to airborne transmission

Authors: Xiangjie Sun, Jessica A Belser, Joanna A Pulit-Penaloza, Nicole Brock, Troy J Kieran, Hui Zeng, Claudia Pappas, Terrence M Tumpey, Taronna R Maines

Journal: MBio

PubMed ID: 38112470

Doi: 10.1128/mbio.02957-23

Products & Services: Recombinant Proteins

Lateralized response of skull bone marrow via osteopontin signaling in mice after ischemia reperfusion

Authors: Chaoran Xu, Qia Zhang, Yi Zhang, Huaijun Chen, Tianchi Tang, Junjie Wang, Siqi Xia, Gao Chen, Jianmin Zhang

Journal: J Neuroinflammation

PubMed ID: 38071333

Doi: 10.1186/s12974-023-02980-x

Products & Services: Proteins, Expression, Isolation and Analysis

The potential of lactose to inhibit cereulide biosynthesis of emetic Bacillus cereus in milk

Authors: Yin Zheng, Wenxing Xu, Hui Guo, Shubo Yu, Liang Xue, Moutong Chen, Jumei Zhang, Zhenlin Xu, Qingping Wu, Juan Wang, Yu Ding

Journal: Int J Food Microbiol

PubMed ID: 38096676

Doi: 10.1016/j.ijfoodmicro.2023.110517

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a rapid assay for β-etherase activity using a novel chromogenic substrate

Authors: Itzel Celeste Romero-Soto, Jorge A Rodríguez, Vicente Paúl Armenta-Pérez, Raúl Balam Martínez-Pérez, Rosa María Camacho-Ruiz, Leociley Rocha Alencar Menezes, Guilherme Lanzi Sassaki, Arquimedes Santana-Filho, María Angeles Camacho-Ruiz

Journal: Talanta

PubMed ID: 38091749

Doi: 10.1016/j.talanta.2023.125501

Products & Services: Codon Optimization

High-fidelity large-diversity monoclonal mammalian cell libraries by cell cycle arrested recombinase-mediated cassette exchange

Authors: Chuan Chen, Zening Wang, Minhyo Kang, Ki Baek Lee, Xin Ge

Journal: Nucleic Acids Res

PubMed ID: 37941133

Doi: 10.1093/nar/gkad1001

Products & Services: Proteins, Expression, Isolation and Analysis

Bu-Shen-Tian-Jing formulas alleviate the mitochondrial damage induced by oxidative stress in ovarian granulosa cells exposed to DEHP through the HDAC3-HSP90AA pathway

Authors: Hui Zhang, Huihua Wang, Qing Zhang, Hui Wang, Yuhang Zhu, Fangfang Wang, Jun Lin, Jue Zhou, Fan Qu

Journal: Pharm Biol

PubMed ID: 37655754

Doi: 10.1080/13880209.2023.2249193

Products & Services: Proteins, Expression, Isolation and Analysis

Crystal structure of ricin toxin A chain complexed with a highly potent pterin-based small-molecular inhibitor

Authors: Masaru Goto, Natsumi Sakamoto, Shoko Higashi, Rena Kawata, Kazuki Nagatsu, Ryota Saito

Journal: J Enzyme Inhib Med Chem

PubMed ID: 37259593

Doi: 10.1080/14756366.2023.2219038

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted mutagenesis of the β-strand DNA binding region of African swine fever virus histone-like protein (pA104R) impairs DNA-binding activity and antibody recognition

Authors: Ana Catarina Urbano, Nicolas Ferreira, Nuno Jordão, Fernando Boinas, Carlos Martins, Fernando Ferreira

Journal: Antiviral Res

PubMed ID: 38103699

Doi: 10.1016/j.antiviral.2023.105784

Products & Services: Molecular Biology Reagents

Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization

Authors: Tong Ye, Zhouguang Jiao, Xin Li, Zhanlong He, Yanyan Li, Fengmei Yang, Xin Zhao, Youchun Wang, Weijin Huang, Meng Qin, Yingmei Feng, Yefeng Qiu, Wenhui Yang, Lingfei Hu, Yaling Hu, Yu Zhai, Erqiang Wang, Di Yu, Shuang Wang, Hua Yue, Yishu Wang, Hengliang Wang, Li Zhu, Guanghui Ma, Wei Wei

Journal: Nature

PubMed ID: 38093012

Doi: 10.1038/s41586-023-06809-8

Products & Services: Molecular Biology Reagents

Functional divergence of a bacterial enzyme promotes healthy or acneic skin

Authors: Irshad A Hajam, Madhusudhanarao Katiki, Randall McNally, María Lázaro-Díez, Stacey Kolar, Avradip Chatterjee, Cesia Gonzalez, Mousumi Paulchakrabarti, Biswa Choudhury, J R Caldera, Trieu Desmond, Chih-Ming Tsai, Xin Du, Huiying Li, Ramachandran Murali, George Y Liu

Journal: Nat Commun

PubMed ID: 38052825

Doi: 10.1038/s41467-023-43833-8

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Generation and Characterization of SORT1-Targeted Antibody-Drug Conjugate for the Treatment of SORT1-Positive Breast Tumor

Authors: Weiliang Zhuang, Wei Zhang, Liping Xie, Lei Wang, Yuan Li, Ziyu Wang, Ao Zhang, Haitao Qiu, Jun Feng, Baohong Zhang, Youjia Hu

Journal: Int J Mol Sci

PubMed ID: 38139459

Doi: 10.3390/ijms242417631

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Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors

Authors: Jody Pacalon, Guillaume Audic, Justine Magnat, Manon Philip, Jérôme Golebiowski, Christophe J Moreau, Jérémie Topin

Journal: Nat Commun

PubMed ID: 38081900

Doi: 10.1038/s41467-023-44058-5

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Targeted mutagenesis of the herpesvirus fusogen central helix captures transition states

Authors: Momei Zhou, Benjamin Vollmer, Emily Machala, Muyuan Chen, Kay Grünewald, Ann M Arvin, Wah Chiu, Stefan L Oliver

Journal: Nat Commun

PubMed ID: 38042814

Doi: 10.1038/s41467-023-43011-w

Products & Services: Proteins, Expression, Isolation and Analysis

Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis

Authors: Xiaojian Shi, Marisa DeCiucis, Kariona A Grabinska, Jean Kanyo, Adam Liu, Tukiet T Lam, Hongying Shen

Journal: Mol Cell

PubMed ID: 38157846

Doi: 10.1016/j.molcel.2023.12.008

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Humoral and cellular immunogenicity and efficacy of a coxsackievirus A10 vaccine in mice

Authors: Huan-Huan An, Meng Li, Rui-Lun Liu, Jie Wu, Sheng-Li Meng, Jing Guo, Ze-Jun Wang, Sha-Sha Qian, Shuo Shen

Journal: Emerg Microbes Infect

PubMed ID: 36373411

Doi: 10.1080/22221751.2022.2147022

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SAXS/WAXS data of conformationally flexible ribose binding protein

Authors: Jagrity Choudhury, Kento Yonezawa, Anu Anu, Nobutaka Shimizu, Barnali Chaudhuri

Journal: Data Brief

PubMed ID: 38178847

Doi: 10.1016/j.dib.2023.109932

Products & Services: Molecular Biology Reagents

Discovery of GPX4 inhibitors through FP-based high-throughput screening

Authors: Yu Cao, Bin Wu, Ying Xu, Mingchen Wang, Xinyu Wu, Xiaochen Liang, Jin Lin, Zhihai Li, Hua Lin, Cheng Luo, Shijie Chen

Journal: Eur J Med Chem

PubMed ID: 38145603

Doi: 10.1016/j.ejmech.2023.116044

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HERPUD1 governs tumor cell mitochondrial function via inositol 1,4,5-trisphosphate receptor-mediated calcium signaling

Authors: Felipe Paredes, Mario Navarro-Marquez, Clara Quiroga, Danica Jiménez-Gallegos, Samantha M Yeligar, Valentina Parra, Marioly Müller, Mario Chiong, Andrew F G Quest, Alejandra San Martin, Sergio Lavandero

Journal: Free Radic Biol Med

PubMed ID: 38043868

Doi: 10.1016/j.freeradbiomed.2023.11.022

Products & Services: Proteins, Expression, Isolation and Analysis

Photosensitizer-singlet oxygen sensor conjugated silica nanoparticles for photodynamic therapy and bioimaging

Authors: Jeladhara Sobhanan, Kenji Ono, Takuya Okamoto, Makoto Sawada, Paul S Weiss, Vasudevanpillai Biju

Journal: Chem Sci

PubMed ID: 38332815

Doi: 10.1039/d3sc03877g

Products & Services: Molecular Biology Reagents

Circ_0000115 Protects Against Cerebral Ischemia Injury by Suppressing Neuronal Apoptosis, Oxidative Stress and Inflammation by miR-1224-5p/Nos3 Axis In Vitro

Authors: Ying Cao, Yanbing Xu, Rui Zhang, Junsheng Qi, Qiuyu Su, Zhiqiang Chen

Journal: Mol Biotechnol

PubMed ID: 38151617

Doi: 10.1007/s12033-023-01005-5

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Antibodies to D7L salivary proteins as a new serological tool to estimate human exposure to mosquitoes

Authors: Sophana Chea, Laura Willen, Sreynik Nhek, Piseth Ly, Kristina Tang, James Oristian, Roberto Salas-Carrillo, Aiyana Ponce, Paola Carolina Valenzuela Leon, Dara Kong, Sokna Ly, Ratanak Sath, Chanthap Lon, Rithea Leang, Rekol Huy, Christina Yek, Jesus G Valenzuela, Eric Calvo, Jessica E Manning, Fabiano Oliveira

Journal: medrxiv

PubMed ID: 38318204

Doi: 10.1101/2023.12.22.23300438

Products & Services: Proteins, Expression, Isolation and Analysis

Cell cycle status of male and female gametes during Arabidopsis reproduction

Authors: Yoav Voichek, Bohdana Hurieva, Caroline Michaud, Anna Schmücker, Zaida Vergara, Bénédicte Desvoyes, Crisanto Gutierrez, Viktoria Nizhynska, Benjamin Jaegle, Michael Borg, Frédéric Berger, Magnus Nordborg, Mathieu Ingouff

Journal: Plant Physiol

PubMed ID: 37757882

Doi: 10.1093/plphys/kiad512

Products & Services: Gene Synthesis

Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule

Authors: Yi-Wen Wu, Wei-Chun HuangFu, Tony Eight Lin, Chao-Hsiang Peng, Huang-Ju Tu, Ting-Yi Sung, Tzu-Ying Sung, Shih-Chung Yen, Shiow-Lin Pan, Kai-Cheng Hsu

Journal: Int J Biol Macromol

PubMed ID: 38163507

Doi: 10.1016/j.ijbiomac.2023.129074

Products & Services: ORF cDNA Clones/MolecularCloud

Injectable CNPs/DMP1-loaded self-assembly hydrogel regulating inflammation of dental pulp stem cells for dentin regeneration

Authors: Yue Zhao, Lutong Song, Mengchen Li, Haoran Peng, Xinyi Qiu, Yuyang Li, Bijun Zhu, Chao Liu, Shuangshuang Ren, Leiying Miao

Journal: Mater Today Bio

PubMed ID: 38170028

Doi: 10.1016/j.mtbio.2023.100907

Products & Services: Proteins, Expression, Isolation and Analysis

Interaction between membrane curvature sensitive factors SpoVM and SpoIVA in Bicelle condition

Authors: Jiali Chen, Yifan Wang, Shuru Lin, Quanxiang Yu, Zhengfei Qi, Wenqi Jiang, Qiang Zhao, Qingshan Bill Fu

Journal: Biochem Biophys Res Commun

PubMed ID: 38141557

Doi: 10.1016/j.bbrc.2023.149395

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