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页码: 43/1072 每页显示数量

Scaffold-enabled high-resolution cryo-EM structure determination of RNA

Authors: Daniel B Haack, Boris Rudolfs, Shouhong Jin, Kevin M Weeks, Navtej Toor

Journal: biorxiv

PubMed ID: 38915706

Doi: 10.1101/2024.06.10.598011

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Arboviruses antagonize insect Toll antiviral immune signaling to facilitate the coexistence of viruses with their vectors

Authors: Dongsheng Jia, Guozhong Luo, Heran Guan, Tingting Yu, Xinyan Sun, Yu Du, Yiheng Wang, Hongyan Chen, Taiyun Wei

Journal: PLoS Pathog

PubMed ID: 38865374

Doi: 10.1371/journal.ppat.1012318

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Auxin resistant 2 and short hypocotyl 2 regulate cotton fiber initiation and elongation

Authors: Fei Jin, Liping Zhu, Liyong Hou, Hongbin Li, Ling Li, Guanghui Xiao

Journal: Plant Physiol

PubMed ID: 38527791

Doi: 10.1093/plphys/kiae183

Products & Services: Protein and Antibody Isolation

Circ_002033 Regulates Proliferation, Apoptosis, and Oxidative Damage of Bovine Mammary Epithelial Cells via the miR-199a-5p-MAP3K11 Axis in Heat Stress

Authors: Hanfang Zeng, Shujie Li, Haomiao Chang, Yunfei Zhai, Haihui Wang, Hantong Weng, Zhaoyu Han

Journal: J Agric Food Chem

PubMed ID: 38869955

Doi: 10.1021/acs.jafc.3c09835

Products & Services: Protein and Antibody Isolation

Immune responses and reinfection of SARS-CoV-2 Omicron variant in patients with lung cancer

Authors: Chen Chen, Xiaoyun Zhou, Xiaoxing Gao, Ruili Pan, Qi He, Xiaobei Guo, Siyuan Yu, Na Wang, Qian Zhao, Mengzhao Wang, Yan Xu, Xiaohong Han

Journal: Int J Cancer

PubMed ID: 38837354

Doi: 10.1002/ijc.35038

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New wheat straw fermentation feed: recombinant efficient degradation of lignocellulose and increase feed protein

Authors: Xihua Chen, Xiaoyu Liang, Na Shi, Lu He, Yi Ma, Daochen Zhu, Zhong Ni, Huayou Chen

Journal: Prep Biochem Biotechnol

PubMed ID: 38824495

Doi: 10.1080/10826068.2024.2353637

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Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp

Authors: Maria A Schumacher, Rajiv R Singh, Raul Salinas

Journal: Nucleic Acids Res

PubMed ID: 38832628

Doi: 10.1093/nar/gkae459

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Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Authors: Olawale G Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M Lange, Cristian Polo Rivera, Tom D Deegan, Yinchen Chen, Melanie Wightman, Rachel Toth, Karim P M Labib, Sebastian Mathea, Neil Ranson, Rubén Fernández-Busnadiego, Miratul M K Muqit

Journal: SCIENCE ADVANCES

PubMed ID: 38848361

Doi: 10.1126/sciadv.adn7191

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TnpB homologues exapted from transposons are RNA-guided transcription factors

Authors: Tanner Wiegand, Florian T Hoffmann, Matt W G Walker, Stephen Tang, Egill Richard, Hoang C Le, Chance Meers, Samuel H Sternberg

Journal: Nature

PubMed ID: 38926585

Doi: 10.1038/s41586-024-07598-4

Understanding the Phase Behavior of a Multistimuli-Responsive Elastin-like Polymer: Insights from Dynamic Light Scattering Analysis

Authors: Peter C Swanson, Galen P Arnold, Carolyn E Curley, Savannah C Wakita, Jeffery D V Waters, Eva Rose M Balog

Journal: J Phys Chem B

PubMed ID: 38830627

Doi: 10.1021/acs.jpcb.4c00070

Products & Services: Molecular Biology Reagents

Production of norovirus-, rotavirus-, and enterovirus-like particles in insect cells is simplified by plasmid-based expression

Authors: Vili Lampinen, Stina Gröhn, Nina Lehmler, Minne Jartti, Vesa P Hytönen, Maren Schubert, Minna M Hankaniemi

Journal: Sci Rep

PubMed ID: 38937523

Doi: 10.1038/s41598-024-65316-6

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C-terminal Poly-histidine Tags Alter Escherichia coli Polyphosphate Kinase Activity and Susceptibility to Inhibition

Authors: Marvin Q Bowlin, Avery D Lieber, Abagail R Long, Michael J Gray

Journal: J Mol Biol

PubMed ID: 38866092

Doi: 10.1016/j.jmb.2024.168651

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IgE-Mediated Sensitization to Blo t 21 and Blo t 5 Is Associated With Asthma in the Tropics: A Case-Control Study

Authors: J Zakzuk, K Donado, E Mondol, V Marrugo, R Regino, J F López, K Hernandez, D Mercado, R Dennis, L Puerta, L Caraballo

Journal: J Investig Allergol Clin Immunol

PubMed ID: 38888580

Doi: 10.18176/jiaci.0892

Products & Services: Molecular Biology Reagents

A soybean cyst nematode suppresses microbial plant symbionts using a lipochitooligosaccharide-hydrolysing enzyme

Authors: Wei Chen, Di Wang, Shaoyong Ke, Yangrong Cao, Wensheng Xiang, Xiaoli Guo, Qing Yang

Journal: Nat Microbiol

PubMed ID: 38886584

Doi: 10.1038/s41564-024-01727-5

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Development of a Ferritin Protein Nanoparticle Vaccine with PRRSV GP5 Protein

Authors: Xinjian Chang, Jun Ma, Yanrong Zhou, Shaobo Xiao, Xun Xiao, Liurong Fang

Journal: Viruses

PubMed ID: 38932282

Doi: 10.3390/v16060991

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Functional characterization of a cystatin A from the bat Myotis davidii

Authors: Gabriel Cerqueira Alves Costa, Ricardo Jose Soares Torquato, Vinícius de Morais Gomes, Lívia Rosa-Fernandes, Giuseppe Palmisano, Aparecida Sadae Tanaka

Journal: Comp Biochem Physiol B Biochem Mol Biol

PubMed ID: 38936799

Doi: 10.1016/j.cbpb.2024.111003

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Assessing Predictive Value of SARS-CoV-2 Epitope-Specific CD8 T-Cell Response in Patients with Severe Symptoms

Authors: Cristina Martín-Martín, Estefanía Salgado Del Riego, Jose R Vidal Castiñeira, Maria Soledad Zapico-Gonzalez, Mercedes Rodríguez-Pérez, Viviana Corte-Iglesias, Maria Laura Saiz, Paula Diaz-Bulnes, Dolores Escudero, Beatriz Suárez-Alvarez, Carlos López-Larrea

Journal: Vaccines (Basel)

PubMed ID: 38932408

Doi: 10.3390/vaccines12060679

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Discovery, characterization, and comparative analysis of new UGT72 and UGT84 family glycosyltransferases

Authors: Tuo Li, Annika J E Borg, Leo Krammer, Hansjörg Weber, Rolf Breinbauer, Bernd Nidetzky

Journal: Commun Chem

PubMed ID: 38942997

Doi: 10.1038/s42004-024-01231-1

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DNA mismatch and damage patterns revealed by single-molecule sequencing

Authors: Mei Hong Liu, Benjamin M Costa, Emilia C Bianchini, Una Choi, Rachel C Bandler, Emilie Lassen, Marta Grońska-Pęski, Adam Schwing, Zachary R Murphy, Daniel Rosenkjær, Shany Picciotto, Vanessa Bianchi, Lucie Stengs, Melissa Edwards, Nuno Miguel Nunes, Caitlin A Loh, Tina K Truong, Randall E Brand, Tomi Pastinen, J Richard Wagner, Anne-Bine Skytte, Uri Tabori, Jonathan E Shoag, Gilad D Evrony

Journal: Nature

PubMed ID: 38867045

Doi: 10.1038/s41586-024-07532-8

Products & Services: Molecular Biology Reagents

Development of Broad-Spectrum Nanobodies for the Therapy and Diagnosis of SARS-CoV-2 and Its Multiple Variants

Authors: Lei He, Qian Wu, Zhaoyong Zhang, Lingling Chen, Kuai Yu, Leibin Li, Qiong Jia, Yanqun Wang, Jianqiang Ni, Chuanbin Wang, Qi Li, Xinyan Zhai, Jincun Zhao, Yuliang Liu, Ruiwen Fan, Yi-Ping Li

Journal: Mol Pharm

PubMed ID: 38920116

Doi: 10.1021/acs.molpharmaceut.4c00165

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Synthetic Peptides Elicit Humoral Response against Porcine Reproductive and Respiratory Syndrome Virus in Swine

Authors: Francisco Perez-Duran, Fernando Calderon-Rico, Luis Enrique Franco-Correa, Alicia Gabriela Zamora-Aviles, Roberto Ortega-Flores, Daniel Durand-Herrera, Alejandro Bravo-Patiño, Ricarda Cortes-Vieyra, Ilane Hernandez-Morales, Rosa Elvira Nuñez-Anita

Journal: Vaccines (Basel)

PubMed ID: 38932381

Doi: 10.3390/vaccines12060652

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mRNA Vaccine for Alzheimer's Disease: Pilot Study

Authors: Armine Hovakimyan, Garri Chilingaryan, Olga King, Joia Kai Capocchi, Jean Paul Chadarevian, Hayk Davtyan, Roman Kniazev, Michael G Agadjanyan, Anahit Ghochikyan

Journal: Vaccines (Basel)

PubMed ID: 38932388

Doi: 10.3390/vaccines12060659

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Exploring a novel GH13_5 α-amylase from Jeotgalibacillus malaysiensis D5 for raw starch hydrolysis

Authors: Nurfatini Radzlin, Mohd Shukuri Mohamad Ali, Kian Mau Goh, Amira Suriaty Yaakop, Iffah Izzati Zakaria, Ummirul Mukminin Kahar

Journal: AMB Express

PubMed ID: 38874807

Doi: 10.1186/s13568-024-01722-3

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Structural and mechanistic insights into a lysosomal membrane enzyme HGSNAT involved in Sanfilippo syndrome

Authors: Boyang Zhao, Zhongzheng Cao, Yi Zheng, Phuong Nguyen, Alisa Bowen, Robert H Edwards, Robert M Stroud, Yi Zhou, Menno Van Lookeren Campagne, Fei Li

Journal: Nat Commun

PubMed ID: 38918376

Doi: 10.1038/s41467-024-49614-1

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Double promoter and tandem gene strategy for efficiently expressing recombinant FGF21

Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang, Xianlong Ye

Journal: Microb Cell Fact

PubMed ID: 38867280

Doi: 10.1186/s12934-024-02447-5

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NbPTR1 confers resistance against Pseudomonas syringae pv actinidiae in kiwifruit

Authors: Shin-Mei Yeh, Minsoo Yoon, Sidney Scott, Abhishek Chatterjee, Lauren M Hemara, Ronan K Y Chen, Tianchi Wang, Kerry Templeton, Erik H A Rikkerink, Jay Jayaraman, Cyril Brendolise

Journal: Plant Cell Environ

PubMed ID: 38899426

Doi: 10.1111/pce.15002

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Interleukin-1 beta (IL-1β) as adjuvant enhances the immune effects of Aeromonas veronii inactivated vaccine in largemouth bass (Micropterus salmoides)

Authors: Ze-Sheng Zhang, Heng-Chu Ren, Xie Gu, Qian-Rong Liang, Hui Fei, Yu-Hong Yang, Shun Yang, Liang-Yin He, Li-Li Liu

Journal: Int J Biol Macromol

PubMed ID: 38876231

Doi: 10.1016/j.ijbiomac.2024.133135

Products & Services: Molecular Biology Reagents

Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2

Authors: J Wouter Beugelink, Els Sweep, Bert J C Janssen, Joost Snijder, Matti F Pronker

Journal: J Mol Biol

PubMed ID: 38852931

Doi: 10.1016/j.jmb.2024.168649

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Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice

Authors: Szu-Hsien Sam Wu, Somi Kim, Heetak Lee, Ji-Hyun Lee, So-Yeon Park, Réka Bakonyi, Isaree Teriyapirom, Natalia Hallay, Sandra Pilat-Carotta, Hans-Christian Theussl, Jihoon Kim, Joo-Hyeon Lee, Benjamin D Simons, Jong Kyoung Kim, Gabriele Colozza, Bon-Kyoung Koo

Journal: Nat Commun

PubMed ID: 38862535

Doi: 10.1038/s41467-024-49382-y

Products & Services: Molecular Biology Reagents

Cost-Efficient Expression of Human Cardiac Myosin Heavy Chain in C2C12 Cells with a Non-Viral Transfection Reagent

Authors: Albin E Berg, Lok Priya Velayuthan, Alf Månsson, Marko Ušaj

Journal: Int J Mol Sci

PubMed ID: 38928453

Doi: 10.3390/ijms25126747

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CircVIRMA enhances cell malignant behavior by governing the miR-452-5p/CREBRF pathway in cervical cancer

Authors: Chengluo Hao, Jianjun Han, Kechao Xiang, Yun Wang, Xiangrui Chen, Chen Yang, Ailin Liang, Li Jia

Journal: Naunyn Schmiedebergs Arch Pharmacol

PubMed ID: 38850300

Doi: 10.1007/s00210-024-03159-8

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Exploring AlphaFold2 s Performance on Predicting Amino Acid Side-Chain Conformations and Its Utility in Crystal Structure Determination of B318L Protein

Authors: Haifan Zhao; Heng Zhang; Zhun She; Zengqiang Gao; Qi Wang; Zhi Geng; Yuhui Dong

Journal: International Journal of Molecular Sciences

PubMed ID: 36769074

Doi: 10.3390/ijms24032740

Temperature-dependent iron motion in extremophile rubredoxins - no need for 'corresponding states'

Authors: Francis E Jenney, Hongxin Wang, Simon J George, Jin Xiong, Yisong Guo, Leland B Gee, Juan José Marizcurrena, Susana Castro-Sowinski, Anna Staskiewicz, Yoshitaka Yoda, Michael Y Hu, Kenji Tamasaku, Nobumoto Nagasawa, Lei Li, Hiroaki Matsuura, Tzanko Doukov, Stephen P Cramer

Journal: Sci Rep

PubMed ID: 38806591

Doi: 10.1038/s41598-024-62261-2

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Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2

Authors: Dan Gao, Wei-Wei Yi, Bo Liu, Cong-En Zhang, Cui-Cui Yang, Li Zeng, Lin Li, Guangbin Luo, Lan Zhang, Zhen-Yu Ju, Jia-Bo Wang

Journal: J Adv Res

PubMed ID: 38704089

Doi: 10.1016/j.jare.2024.04.027

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CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma

Authors: Lin Tan, Han Zhang, Yun Ding, Yangyun Huang, Daqiang Sun

Journal: Sci Rep

PubMed ID: 38755183

Doi: 10.1038/s41598-024-61804-x

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Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4

Authors: Jianyao Zeng, Yuan Fang, Zixuan Zhang, Zhenzhen Lv, Xiaodie Wang, Qian Huang, Zhidan Tian, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Jing Yu, Tao Liu, Qijun Qian

Journal: Oncogene

PubMed ID: 38806619

Doi: 10.1038/s41388-024-03066-5

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A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy

Authors: Dan A Tudorica, Bishal Basak, Alexia S Puerta Cordova, Grace Khuu, Kevin Rose, Michael Lazarou, Erika L F Holzbaur, James H Hurley

Journal: J Cell Biol

PubMed ID: 38728007

Doi: 10.1083/jcb.202309015

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Post-transcriptional regulation of the T-box gene midline via the 3'UTR in Drosophila is complex and cell and tissue-dependent

Authors: Kalpana Makhijani, Jordan Mar, Ivana Gaziova, Krishna Moorthi Bhat

Journal: Genetics

PubMed ID: 38805187

Doi: 10.1093/genetics/iyae087

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Stacked mutations in wheat homologues of rice SEMI-DWARF1 confer a novel semi-dwarf phenotype

Authors: Barbora Ndreca, Alison Huttly, Sajida Bibi, Carlos Bayon, George Lund, Joshua Ham, Rocío Alarcón-Reverte, John Addy, Danuše Tarkowská, Stephen Pearce, Peter Hedden, Stephen G Thomas, Andrew L Phillips

Journal: BMC Plant Biol

PubMed ID: 38724935

Doi: 10.1186/s12870-024-05098-1

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Acts as a Positive Regulator of Secondary Cell Wall Synthesis in Sudan Grass ( S)

Authors: Yanzhong Huang, Juanzi Wu, Jianyu Lin, Zhiwei Liu, Zhengfeng Mao, Chen Qian, Xiaoxian Zhong

Journal: Plants (Basel)

PubMed ID: 38794423

Doi: 10.3390/plants13101352

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Accuracy of Anti-SARS-CoV-2 Antibody in Comparison with Surrogate Viral Neutralization Test in Persons Living with HIV, Systemic Lupus Erythematosus, and Chronic Kidney Disease

Authors: Marita Restie Tiara, Chrisan Bimo Prayuda, Tara Titian Maulidya, Hofiya Djauhari, Dadang Suhendar, Rudi Wisaksana, Laniyati Hamijoyo, Rudi Supriyadi, Agnes Rengga Indrati, Bachti Alisjahbana

Journal: Vaccines (Basel)

PubMed ID: 38793809

Doi: 10.3390/vaccines12050558

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Identification and characterization of calcium binding protein, spermatid-associated 1 (CABS1)# in selected human tissues and fluids

Authors: Eduardo Reyes-Serratos, Joy Ramielle L Santos, Lakshmi Puttagunta, Stephen J Lewis, Mechiko Watanabe, Aron Gonshor, Robert Buck, A Dean Befus, Marcelo Marcet-Palacios

Journal: PLoS ONE

PubMed ID: 38753592

Doi: 10.1371/journal.pone.0301855

Development and validation of an HILIC/MS/MS method for determination of nusinersen in rabbit plasma

Authors: Xiao Zhang, Chunjie Sha, Wei Zhang, Fengjuan Zhao, Mingli Zhu, Guangyi Leng, Wanhui Liu

Journal: Heliyon

PubMed ID: 38799737

Doi: 10.1016/j.heliyon.2024.e31213

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Design of antiviral AGO2-dependent short hairpin RNAs

Authors: Yuanyuan Bie, Jieling Zhang, Jiyao Chen, Yumin Zhang, Muhan Huang, Leike Zhang, Xi Zhou, Yang Qiu

Journal: Virol Sin

PubMed ID: 38734183

Doi: 10.1016/j.virs.2024.05.001

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4-Octyl Itaconate Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis Via Regulating Microglia

Authors: Ning Zhao, Ming Yi, Lin-Jie Zhang, Qiu-Xia Zhang, Li Yang

Journal: Inflammation

PubMed ID: 38761250

Doi: 10.1007/s10753-024-02050-1

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Effect of Free Cysteine Residues to Serine Mutation on Cellodextrin Phosphorylase

Authors: Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi

Journal: J Appl Glycosci (1999)

PubMed ID: 38863949

Doi: 10.5458/jag.jag.JAG-2023_0011

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A systematic analysis of affinity tags in the haloarchaeal expression system, for protein purification

Authors: Ram Karan, Dominik Renn, Thorsten Allers, Magnus Rueping

Journal: Front Microbiol

PubMed ID: 38873150

Doi: 10.3389/fmicb.2024.1403623

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CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice

Authors: Henriette Reventlow Frederiksen, Alexandra Glantz, Kåre Kryger Vøls, Søren Skov, Pernille Tveden-Nyborg, Kristine Freude, Ulrik Doehn

Journal: Front Genome Ed

PubMed ID: 38863835

Doi: 10.3389/fgeed.2024.1403395

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Understanding the Enzyme ()-Norcoclaurine Synthase Promiscuity to Aldehydes and Ketones

Authors: Brunno A Salvatti, Marcelo A Chagas, Phillipe O Fernandes, Yan F X Ladeira, Aline S Bozzi, Veronica S Valadares, Ana Paula Valente, Amanda S de Miranda, Willian R Rocha, Vinicius G Maltarollo, Adolfo H Moraes

Journal: J Chem Inf Model

PubMed ID: 38776464

Doi: 10.1021/acs.jcim.3c01773

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Therapeutic potentials of nonpeptidic V2R agonists for partial cNDI-causing V2R mutants

Authors: Ritsuki Kuramoto, Ryoji Kise, Mayu Kanno, Kouki Kawakami, Tatsuya Ikuta, Noriko Makita, Asuka Inoue

Journal: PLoS ONE

PubMed ID: 38748623

Doi: 10.1371/journal.pone.0303507

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