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Production of VP3-only virus-like particles of Adeno-associated virus 2 in E coli cells

Authors: Chengyu Fu, Shruthi Gobbooru, Ashley T Martino, Woon-Kai Low

Journal: Protein Expr Purif

PubMed ID: 38754753

Doi: 10.1016/j.pep.2024.106502

Products & Services: Catalog Antibodies

Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis

Authors: Zhixin Ma, Yu Sun, Yang Yu, Wenjun Xiao, Zhijie Xiao, Tianyu Zhong, Xi Xiang, Zhigang Li

Journal: Cell Commun Signal

PubMed ID: 38802814

Doi: 10.1186/s12964-024-01669-9

Analysis of the molecular basis for the non-amylolytic and non-proteolytic nature of Aspergillus vadensis CBS 113365

Authors: Dujuan Liu, Sandra Garrigues, Helena Culleton, Vincent A McKie, Ronald P de Vries

Journal: N Biotechnol

PubMed ID: 38697469

Doi: 10.1016/j.nbt.2024.04.003

Products & Services: Gene Synthesis

Single-molecule assay guided crRNA optimization enhances specific microRNA detection by CRISPR-Cas12a

Authors: Kaizhao Chen, Wenjun Sun, Mingtian Zhong, Jiaqi Xie, Yongkun Huo, Xiuqi Lu, Ziting Chen, Bo Sun, Xingxu Huang, Xinjie Wang， Ming Liu , Xiaodong Ma, Peixiang Ma

Journal: Sensors and Actuators B: Chemical

Doi: 10.1016/j.snb.2024.135389

Products & Services: Protein Electrophoresis and Western

Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells

Authors: Renate L M Jansen, Rinse de Boer, Eline M F de Lange, Janet Koster, Rifka Vlijm, Hans R Waterham, Ida J van der Klei

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38762172

Doi: 10.1016/j.bbamcr.2024.119754

Products & Services: Molecular Biology Reagents

Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants

Authors: Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson, Thea K. Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L. Powell, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen & Rasmus Hartmann-Petersen

Journal: Nat Commun

PubMed ID: 38740822

Doi: 10.1038/s41467-024-48481-0

Products & Services: Mutagenesis Services

Biosynthetic production of anticoagulant heparin polysaccharides through metabolic and sulfotransferases engineering strategies

Authors: Jian-Qun Deng, Yi Li, Yu-Jia Wang, Ya-Lin Cao, Si-Yu Xin, Xin-Yu Li, Rui-Min Xi, Feng-Shan Wang & Ju-Zheng Sheng

Journal: Nat Commun

PubMed ID: 38704385

Doi: 10.1038/s41467-024-48193-5

Products & Services: Gene Synthesis

A Customized Biohybrid presenting Cascade Responses to Tumor Microenvironment

Authors: Feiyu Li, Peipei Zhu, Bingzhu Zheng, Zijie Lu, Chao Fang, Yike Fu, Xiang Li

Journal: Adv Mater

PubMed ID: 38723206

Doi: 10.1002/adma.202404901

Products & Services: Molecular Biology Reagents

Thalidomide derivatives degrade BCL-2 by reprogramming the binding surface of CRBN

Authors: Jianhui Wang (王建辉) , Marcel Heinz, Kang Han (韩康), Varun J. Shah, Sebastian Hasselbeck, Martin P. Schwalm, Rajeshwari Rathore, Gerhard Hummer, Jun Zhou (周俊), Ivan Dikic, Xinlai Cheng (承辛来)

Journal: Cell Reports Physical Science

Doi: doi.org/10.1016/j.xcrp.2024.101960

Products & Services: Molecular Biology Reagents

C9orf72-Associated Dipeptide Repeat Expansions Perturb ER-Golgi Vesicular Trafficking, Inducing Golgi Fragmentation and ER Stress, in ALS/FTD

Authors: Jessica Sultana, Audrey M G Ragagnin, Sonam Parakh, Sayanthooran Saravanabavan, Kai Ying Soo, Marta Vidal, Cyril Jones Jagaraj, Kunjie Ding, Sharlynn Wu, Sina Shadfar, Emily K Don, Anand Deva, Garth Nicholson, Dominic B Rowe, Ian Blair, Shu Yang, Julie D Atkin

Journal: Mol Neurobiol

PubMed ID: 38722513

Doi: 10.1007/s12035-024-04187-4

Products & Services: PCR Cloning and Subcloning

Polyglutamine-mediated ribotoxicity disrupts proteostasis and stress responses in Huntington's disease

Authors: Ranen Aviner, Ting-Ting Lee, Vincent B Masto, Kathy H Li, Raul Andino, Judith Frydman

Journal: Nat Cell Biol

PubMed ID: 38741019

Doi: 10.1038/s41556-024-01414-x

Products & Services: ORF cDNA Clones/MolecularCloud

A PACAP-activated network for secretion requires coordination of Ca influx and Ca mobilization

Authors: Xiaohuan Chen, Nicole A Bell, Breanna L Coffman, Agustin A Rabino, Rafael Garcia-Mata, Paul J Kammermeier, David I Yule, Daniel Axelrod, Alan V Smrcka, David R Giovannucci, Arun Anantharam

Journal: Mol Biol Cell

PubMed ID: 38758660

Doi: 10.1091/mbc.E24-02-0083

Products & Services: Molecular Biology Reagents

Disulfidptosis in head and neck squamous carcinoma: Integrative bioinformatic and in-vitro analysis

Authors: Xufeng Huang, Jinyan Yang, Qi Wang, Rao Fu, Xutao Wen, Zhengrui Li, Ling Zhang

Journal: Oral Dis

PubMed ID: 38696646

Doi: 10.1111/odi.14977

Products & Services: Molecular Biology Reagents

Two-point immobilization of M3 muscarinic receptor: a method for recognizing receptor antagonists in natural products

Authors: Xiaomin Huang, Ting Wang, Ludan Wang, Yantao Sun, Ziru Zhang, Yajun Zhang

Journal: BMC Chem

PubMed ID: 38702791

Doi: 10.1186/s13065-024-01198-z

Products & Services: DNA Sequencing

Lysineless HiBiT and NanoLuc Tagging Systems as Alternative Tools Monitoring Targeted Protein Degradation

Authors: Hanfeng Lin, Kristin Riching, May Poh Lai, Dong Lu, Ran Cheng, Xiaoli Qi, Jin Wang

Journal: biorxiv

PubMed ID: 38798562

Doi: 10.1101/2024.05.14.594249

Products & Services: Molecular Biology Reagents

Novel enzymes for biodegradation of polycyclic aromatic hydrocarbons identified by metagenomics and functional analysis in short-term soil microcosm experiments

Authors: Kinga K Nagy, Kristóf Takács, Imre Németh, Bálint Varga, Vince Grolmusz, Mónika Molnár, Beáta G Vértessy

Journal: Sci Rep

PubMed ID: 38773163

Doi: 10.1038/s41598-024-61566-6

Products & Services: Gene Synthesis

Nonspecific phospholipases C3 and C4 interact with PIN-FORMED2 to regulate growth and tropic responses in Arabidopsis

Authors: Teng Li, Shujuan Zhang, Shuaibing Yao, Xuebing Li, Qianru Jia, Jingya Yuan, Wenhua Zhang, Xuemin Wang, Qun Zhang

Journal: Plant Cell

PubMed ID: 38442314

Doi: 10.1093/plcell/koae071

Products & Services: Protein and Antibody Isolation

Structural characterization of E22G Aβ fibrils H detected MAS NMR

Authors: Natalie C Golota, Brian Michael, Edward P Saliba, Sara Linse, Robert G Griffin

Journal: Phys Chem Chem Phys

PubMed ID: 38715538

Doi: 10.1039/d4cp00553h

Products & Services: Molecular Biology Reagents

Arg-biodynamers as antibiotic potentiators through interacting with Gram-negative outer membrane lipopolysaccharides

Authors: Mohamed A M Kamal, Justine Bassil, Brigitta Loretz, Anna K H Hirsch, Sangeun Lee, Claus-Michael Lehr

Journal: Eur J Pharm Biopharm

PubMed ID: 38795784

Doi: 10.1016/j.ejpb.2024.114336

Products & Services: Catalog Peptides

Deletion of Asb15b gene can lead to a significant decrease in zebrafish intermuscular bone

Authors: Minghui Niu, Huamin Whang, Zhichao Wu, Shouwen Jiang, Liangbiao Chen

Journal: Gene

PubMed ID: 38754570

Doi: 10.1016/j.gene.2024.148561

Cysteine, sodium metabisulfite, and glutathione enhance crosslinking between proteins during high moisture meat analog extrusion processing and may improve the fibrousness of the products

Authors: Jana K Richter, Preston Watanabe, Josh Bernin, Brennan Smith, Rachel Mitacek, Girish M Ganjyal

Journal: J Sci Food Agric

PubMed ID: 38804791

Doi: 10.1002/jsfa.13569

Products & Services: Protein Electrophoresis and Western

Nanobody-based immunosensor for the detection of H pylori in saliva

Authors: Mohammad Ia Ahmad, Célia G Amorim, Luay F Abu Qatouseh, Maria C B S M Montenegro

Journal: Biosens Bioelectron

PubMed ID: 38810413

Doi: 10.1016/j.bios.2024.116423

Products & Services: Gene Synthesis

for Deciphering Selenium-Encoded Peptide and a Pyrolysis-Thermolysis Dietary Model for Minimizing Loss of "KKSe(M)R" during Processing

Authors: Xin Wang, Wei Jia

Journal: J Agric Food Chem

PubMed ID: 38770928

Doi: 10.1021/acs.jafc.4c01638

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Cellular metabolism of substance P produces neurokinin-1 receptor peptide agonists with diminished cyclic AMP signaling

Authors: Tamas Kriska, Jayashree Natarajan, Anja Herrnreiter, Sang-Kyu Park, Sandra L Pfister, Michael J Thomas, Alexander Widiapradja, Scott P Levick, William B Campbell

Journal: Am J Physiol Cell Physiol

PubMed ID: 38798270

Doi: 10.1152/ajpcell.00103.2024

Products & Services: Molecular Biology Reagents

CYP116B5-SOX: An artificial peroxygenase for drug metabolites production and bioremediation

Authors: Daniele Giuriato, Gianluca Catucci, Danilo Correddu, Giovanna Di Nardo, Gianfranco Gilardi

Journal: Biotechnol J

PubMed ID: 38719620

Doi: 10.1002/biot.202300664

Products & Services: Custom Vector Construction

Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling

Authors: Nydia Tejeda-Muñoz, Yagmur Azbazdar, Eric A Sosa, Julia Monka, Pu-Sheng Wei, Grace Binder, Kuo-Ching Mei, Yerbol Z Kurmangaliyev, Edward M De Robertis

Journal: Biol Open

PubMed ID: 38713004

Doi: 10.1242/bio.060269

Products & Services: PCR Cloning and Subcloning

Cloning and functional characterization of novel human neutralizing anti-interferon-alpha and anti-interferon-beta antibodies

Authors: Emmanouil Papasavvas, Lily Lu, Matthew Fair, Isabela Oliva, Joel Cassel, Sonali Majumdar, Karam Mounzer, Jay R Kostman, Pablo Tebas, Amit Bar-Or, Kar Muthumani, Luis J Montaner

Journal: biorxiv

PubMed ID: 38746170

Doi: 10.1101/2024.05.05.591636

Products & Services: Recombinant Proteins

Nanoemulsions and nanocapsules as carriers for the development of intranasal mRNA vaccines

Authors: Mireya L Borrajo, Gustavo Lou, Shubaash Anthiya, Philipp Lapuhs, David Moreira Álvarez, Araceli Tobío, María Isabel Loza, Anxo Vidal, María José Alonso

Journal: Drug Deliv Transl Res

PubMed ID: 38811465

Doi: 10.1007/s13346-024-01635-5

Products & Services: Catalog Peptides

Single-shot dendritic cell targeting SARS-CoV-2 vaccine candidate induces broad, durable and protective systemic and mucosal immunity in mice

Authors: Nicholas You Zhi Cheang, Kai Sen Tan, Peck Szee Tan, Kiren Purushotorma, Wee Chee Yap, Kirsteen McInnes Tullett, Benson Yen Leong Chua, Aileen Ying-Yan Yeoh, Caris Qi Hui Tan, Xinlei Qian, Huixin Chen, Douglas Jie Wen Tay, Irina Caminschi, Yee Joo Tan, Paul Anthony Macary, Chee Wah Tan, Mireille Hanna Lahoud, Sylvie Alonso

Journal: Mol Ther

PubMed ID: 38715364

Doi: 10.1016/j.ymthe.2024.05.003

Products & Services: Serology SARS-Cov-2 detection kits

E3 ubiquitin ligase RNF2 protects polymerase ι from destabilization

Authors: Mikolaj Fedorowicz, Agnieszka Halas, Matylda Macias, Ewa Sledziewska-Gojska, Roger Woodgate, Justyna McIntyre

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38705361

Doi: 10.1016/j.bbamcr.2024.119743

Products & Services: Molecular Biology Reagents

An integrated multi-omics approach reveals polymethoxylated flavonoid biosynthesis in Citrus reticulata cv Chachiensis

Authors: Jiawen Wen, Yayu Wang, Xu Lu, Huimin Pan, Dian Jin, Jialing Wen, Canzhi Jin, Sunil Kumar Sahu, Jianmu Su, Xinyue Luo, Xiaohuan Jin, Jiao Zhao, Hong Wu, E-Hu Liu, Huan Liu

Journal: Nat Commun

PubMed ID: 38734724

Doi: 10.1038/s41467-024-48235-y

Products & Services: Recombinant Proteins

Early Animal Origin of BACE1 APP/Aβ Proteolytic Function

Authors: James A Langeland, Lillian Baumann, Eva M DeYoung, Raphaela Angelina Varella, Nkatha Mwenda, Alejandro Aguirre, D Blaine Moore

Journal: Biology (Basel)

PubMed ID: 38785802

Doi: 10.3390/biology13050320

Products & Services: Gene Synthesis

Three in one: An effective and universal vaccine expressing heterologous tandem RBD trimer by rabies virus vector protects mice against SARS-CoV-2

Authors: Jingbo Huang, Weiqi Wang, Hailun Li, Yujie Bai, Yumeng Song, Cuicui Jiao, Hongli Jin, Pei Huang, Haili Zhang, Xianzhu Xia, Feihu Yan, Yuanyuan Li, Hualei Wang

Journal: Antiviral Res

PubMed ID: 38740191

Doi: 10.1016/j.antiviral.2024.105905

Products & Services: Gene Synthesis

Generation and evaluation of cancer binding capacity of HLA-A2-WT1 complex-targeting antibody

Authors: Xue Yao, Sandro Matosevic

Journal: Immunol Lett

PubMed ID: 38810886

Doi: 10.1016/j.imlet.2024.106881

Products & Services: Molecular Biology Reagents

Transcriptome dynamics of the BHK21 cell line in response to human coronavirus OC43 infection

Authors: Mianhuan Li, Yang Yang, Pusen Wang, Weitao Que, Lin Zhong, Zhao Cai, Yang Liu, Liang Yang, Yingxia Liu

Journal: Microbiol Res

PubMed ID: 38761489

Doi: 10.1016/j.micres.2024.127750

Products & Services: Protein and Antibody Isolation

A glutathione S-transferase from confers resistance to Fusarium head blight in wheat

Authors: Lanfei Zhao, Amy Bernardo, Fanmei Kong, Wei Zhao, Yanhong Dong, Hyeonju Lee, Harold N Trick, Jessica Rupp Noller, Guihua Bai

Journal: Phytopathology

PubMed ID: 38709206

Doi: 10.1094/PHYTO-03-24-0106-SC

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer

Authors: Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao

Journal: Front Pharmacol

PubMed ID: 38835669

Doi: 10.3389/fphar.2024.1392328

Products & Services: Gene Synthesis

Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity

Authors: Fanomezana M Ranaivoson, Rieke Bande, Isabell Cardaun, Antonio De Riso, Annette Gärtner, Pui Loke, Christina Reinisch, Prasuna Vogirala, Edward Beaumont

Journal: IUCrJ

PubMed ID: 38656308

Doi: 10.1107/S2052252524002549

Products & Services: Molecular Biology Reagents

CXCR3 participates in asymmetric division of mouse oocytes by modulating actin dynamics

Authors: Wei-Jian Li, Rong-Yang Li, Da-Yu Wang, Ming Shen, Hong-Lin Liu

Journal: Theriogenology

PubMed ID: 38788628

Doi: 10.1016/j.theriogenology.2024.05.028

Products & Services: Protein and Antibody Isolation

Intranasal Vaccination with a Respiratory-Syncytial-Virus-Based Virus-like Particle Displaying the G Protein Conserved Region Induces Severe Weight Loss and Pathology upon Challenge with Wildtype Respiratory Syncytial Virus

Authors: Megolhubino Terhüja, Manjunath Siddappa, Pramila Lamichhane, Chetan D Meshram, Timothy A Snider, Jerry W Ritchey, Antonius G P Oomens

Journal: Viruses

PubMed ID: 38932136

Doi: 10.3390/v16060843

Products & Services: Catalog Antibodies

Systemic LPS Administration Stimulates the Activation of Non-Neuronal Cells in an Experimental Model of Spinal Muscular Atrophy

Authors: Eleni Karafoulidou, Evangelia Kesidou, Paschalis Theotokis, Chrystalla Konstantinou, Maria-Konstantina Nella, Iliana Michailidou, Olga Touloumi, Eleni Polyzoidou, Ilias Salamotas, Ofira Einstein, Athanasios Chatzisotiriou, Marina-Kleopatra Boziki, Nikolaos Grigoriadis

Journal: Cells

PubMed ID: 38727321

Doi: 10.3390/cells13090785

Products & Services: Protein and Antibody Isolation

Investigating the Antimicrobial Effects of a Novel Peptide Derived From Listeriolysin S on , and : An In Silico and In Vitro Study

Authors: Mojgan Sarabi Nobakht, Kaveh Bazyar, Mohammad Sadegh Ghalyanchi Langeroudi, Mandana Mirzaei, Mehdi Goudarzi, Ali Shivaee

Journal: Bioinform Biol Insights

PubMed ID: 38765021

Doi: 10.1177/11779322241252513

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Modified Zhenwu Tang delays chronic renal failure progression by modulating oxidative stress and hypoxic responses in renal proximal tubular epithelial cells

Authors: Yuan-Yuan Zhang, Pei-Pei Jin, Deng-Zhou Guo, Dong Bian

Journal: Heliyon

PubMed ID: 38803876

Doi: 10.1016/j.heliyon.2024.e31265

Products & Services: Protein and Antibody Isolation

SARS-CoV-2 Surveillance of Wild Mice and Rats in North American Cities

Authors: Lisa K F Lee, Chelsea G Himsworth, Natalie Prystajecky, Antonia Dibernardo, L Robbin Lindsay, Theresa M Albers, Rajeev Dhawan, Ken Henderson, Guy Mulder, Harveen K Atwal, Imara Beattie, Bruce K Wobeser, Michael H Parsons, Kaylee A Byers

Journal: Ecohealth

PubMed ID: 38748281

Doi: 10.1007/s10393-024-01679-6

Products & Services: Molecular Biology Reagents

Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes

Authors: Noam Levin, Sanghyun P Kim, Charles A Marquardt, Nolan R Vale, Zhiya Yu, Sivasish Sindiri, Jared J Gartner, Maria Parkhurst, Sri Krishna, Frank J Lowery, Nikolaos Zacharakis, Lior Levy, Todd D Prickett, Tiffany Benzine, Satyajit Ray, Robert V Masi, Billel Gasmi, Yong Li, Rafiqul Islam, Alakesh Bera, Stephanie L Goff, Paul F Robbins, Steven A Rosenberg

Journal: J Immunother Cancer

PubMed ID: 38816232

Doi: 10.1136/jitc-2023-008645

Products & Services: Gene Synthesis

Application of MALDI-MS for characterization of fucoidan hydrolysates and screening of endo-fucoidanase activity

Authors: Diego S Reyes-Weiss, Margot Bligh, Nanna Rhein-Knudsen, Jan-Hendrik Hehemann, Manuel Liebeke, Bjørge Westereng, Svein Jarle Horn

Journal: Carbohydr Polym

PubMed ID: 38858030

Doi: 10.1016/j.carbpol.2024.122317

Products & Services: Molecular Biology Reagents

Selective activation of naïve B cells with unique epitope specificity shapes autoantibody formation in celiac disease

Authors: Saykat Das, Jorunn Stamnaes, Lene S Høydahl, Christine Skagen, Knut E A Lundin, Jørgen Jahnsen, Ludvig M Sollid, Rasmus Iversen

Journal: J Autoimmun

PubMed ID: 38754235

Doi: 10.1016/j.jaut.2024.103241

Products & Services: Gene Synthesis

Structural basis for raccoon dog receptor recognition by SARS-CoV-2

Authors: Fu-Chun Hsueh, Ke Shi, Alise Mendoza, Fan Bu, Wei Zhang, Hideki Aihara, Fang Li

Journal: PLoS Pathog

PubMed ID: 38709834

Doi: 10.1371/journal.ppat.1012204

Products & Services: Molecular Biology Reagents

Development of multiplexed orthogonal base editor (MOBE) systems

Authors: Quinn T Cowan, Sifeng Gu, Wanjun Gu, Brodie L Ranzau, Tatum S Simonson, Alexis C Komor

Journal: Nat Biotechnol

PubMed ID: 38773305

Doi: 10.1038/s41587-024-02240-0

Products & Services: Codon Optimization

The Hansenula polymorpha mitochondrial carrier family protein Mir1 is dually localized at peroxisomes and mitochondria

Authors: Marc Pilegaard Pedersen, Justina C Wolters, Rinse de Boer, Arjen M Krikken, Ida J van der Klei

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38702017

Doi: 10.1016/j.bbamcr.2024.119742

Products & Services: Codon Optimization