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Impact of surface receptors TLR2, CR3, and FcγRIII on Rhodococcus equi phagocytosis and intracellular survival in macrophages

Authors: Bibiana Petri da Silveira , Rola Barhoumi , Jocelyne M Bray , Hannah M Cole-Pfeiffer , Cory J Mabry , Robert C Burghardt , Noah D Cohen, Angela I Bordin

Journal: Immunity

PubMed ID: 38018994

Doi: 10.1128/iai.00383-23

Products & Services: Plasmid DNA Preparation

The HIV capsid mimics karyopherin engagement of FG-nucleoporins

Authors: C. F. Dickson, S. Hertel, A. J. Tuckwell, N. Li, J. Ruan, S. C. Al-Izzi, N. Ariotti, E. Sierecki, Y. Gambin, R. G. Morris, G. J. Towers, T. Böcking & D. A. Jacques

Journal: Nature

PubMed ID: 38267582

Doi: 10.1038/s41586-023-06969-7

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The cryo-EM structure of homotetrameric attachment glycoprotein from langya henipavirus

Authors: Yingying Guo , Songyue Wu , Wenting Li , Haonan Yang , Tianhao Shi , Bin Ju , Zheng Zhang , Renhong Yan

Journal: Nat Commun

PubMed ID: 38280880

Doi: 10.1038/s41467-024-45202-5

Products & Services: Recombinant Antibody Expression

Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Authors: Eike-Christian Wamhoff , Larance Ronsard , Jared Feldman , Grant A Knappe , Blake M Hauser , Anna Romanov , James Brett Case , Shilpa Sanapala , Evan C Lam , Kerri J St Denis , Julie Boucau , Amy K Barczak , Alejandro B Balazs , Michael S Diamond , Aaron G Schmidt , Daniel Lingwood , Mark Bathe

Journal: Nat Commun

PubMed ID: 38291019

Doi: 10.1038/s41467-024-44869-0

Products & Services: PCR Cloning and Subcloning

Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy

Authors: Binh An Nguyen , Virender Singh , Shumaila Afrin , Anna Yakubovska , Lanie Wang , Yasmin Ahmed , Rose Pedretti , Maria Del Carmen Fernandez-Ramirez , Preeti Singh , Maja Pękała , Luis O Cabrera Hernandez , Siddharth Kumar , Andrew Lemoff , Roman Gonzalez-Prieto , Michael R Sawaya , David S Eisenberg , Merrill Douglas Benson , Lorena Saelices

Journal: Nat Commun

PubMed ID: 38233397

Doi: 10.1038/s41467-024-44820-3

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STYXL1 regulates CCT complex assembly and flagellar tubulin folding in sperm formation

Authors: Yu Chen , Mengjiao Luo , Haixia Tu , Yaling Qi , Yueshuai Guo , Xiangzheng Zhang , Yiqiang Cui , Mengmeng Gao , Xin Zhou , Tianyu Zhu , Hui Zhu , Chenghao Situ , Yan Li , Xuejiang Guo

Journal: Nat Commun

PubMed ID: 38168070

Doi: 10.1038/s41467-023-44337-1

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Cryo-EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH

Authors: Niraj Kumar , Shivani Sharma , Prem S Kaushal

Journal: Nat Commun

PubMed ID: 38245551

Doi: 10.1038/s41467-024-44879-y

Products & Services: Gene Synthesis

Biomimetic Control over Bimetallic Nanoparticle Structure and Activity via Peptide Capping Ligand Sequence

Authors: Maichong Xie, Ryuichi Shimogawa, Yang Liu, Lihua Zhang, Alexandre C. Foucher, Prahlad K. Routh, Eric A. Stach, Anatoly I. Frenkel*, and Marc R. Knecht

Journal: ACS Nano

PubMed ID: 38227802

Doi: 10.1021/acsnano.3c10016

Products & Services: Peptide Synthesis

Cross-feeding promotes heterogeneity within yeast cell populations

Authors: Kevin K Y Hu, Ankita Suri, Geoff Dumsday, Victoria S Haritos

Journal: Nat Commun

PubMed ID: 38200012

Doi: 10.1038/s41467-023-44623-y

Products & Services: Codon Optimization

Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake

Authors: Kazuki Takeda, Taki Saito, Sakura Sasaki, Akifumi Eguchi, Makoto Sugiyama, Saeka Eto, Kio Suzuki, Ryo Kamata

Journal: Toxics

PubMed ID: 38251008

Doi: 10.3390/toxics12010052

Products & Services: DNA Sequencing

Single-Molecule Analysis of SARS-CoV-2 Double-Stranded Polynucleotides Using Solid-State Nanopore with AI-Assisted Detection and Classification: Implications for Understanding Disease Severity

Authors: Ibrar Alam, Thitikorn Boonkoom, Harit Pitakjakpipop, Poramin Boonbanjong, Kawin Loha, Thanaya Saeyang, Jarunee Vanichtanankul, Deanpen Japrung

Journal: ACS Appl Bio Mater

PubMed ID: 38194666

Doi: 10.1021/acsabm.3c00998

Products & Services: PCR Cloning and Subcloning

Safety, Immunogenicity, and Mechanism of a Rotavirus mRNA-LNP Vaccine in Mice

Authors: Chenxing Lu, Yan Li, Rong Chen, Xiaoqing Hu, Qingmei Leng, Xiaopeng Song, Xiaochen Lin, Jun Ye, Jinlan Wang, Jinmei Li, Lida Yao, Xianqiong Tang, Xiangjun Kuang, Guangming Zhang, Maosheng Sun, Yan Zhou, Hongjun Li

Journal: Viruses

PubMed ID: 38399987

Doi: 10.3390/v16020211

Products & Services: Molecular Biology Reagents

Efficient treatment of colon cancer with codelivery of TRAIL and imatinib by liposomes

Authors: Rongrong Fu, Rui Chang, Andong Peng, Changshun Feng, Weifan Zhu, Yi Chen, Xue Tian, Rui Wang, Hui Yan, Dianlong Jia, Jun Li

Journal: Pharm Dev Technol

PubMed ID: 38230653

Doi: 10.1080/10837450.2024.2301763

Products & Services: Proteins, Expression, Isolation and Analysis

Structural insights into the activation and inhibition of CXC chemokine receptor 3

Authors: Haizhan Jiao, Bin Pang, Aijun Liu, Qiang Chen, Qi Pan, Xiankun Wang, Yunong Xu, Ying-Chih Chiang, Ruobing Ren, Hongli Hu

Journal: Nat Struct Mol Biol

PubMed ID: 38177682

Doi: 10.1038/s41594-023-01175-5

Products & Services: Proteins, Expression, Isolation and Analysis

Host protein EPCAM interacting with EtMIC8-EGF is essential for attachment and invasion of Eimeria tenella in chickens

Authors: Lingyu Sun, Chao Li, Ningning Zhao, Bingxiang Wang, Hongmei Li, Hairong Wang, Xiao Zhang, Xiaomin Zhao

Journal: Microb Pathog

PubMed ID: 38281605

Doi: 10.1016/j.micpath.2024.106549

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering for Sustainable Production of the Pomegranate Seed Oil-Derived Punicic Acid

Authors: Kaifeng Wang, Yueyue Zhou, Lizhen Cao, Lu Lin, Rodrigo Ledesma-Amaro, Xiao-Jun Ji

Journal: J Agric Food Chem

PubMed ID: 38282297

Doi: 10.1021/acs.jafc.3c08718

Products & Services: Gene Synthesis

Up-regulation of lncRNA WT1-AS ameliorates Aβ-stimulated neuronal injury through modulation of miR-186-5p/CCND2 axis in Alzheimer's disease

Authors: Yun Tang, Xiaojiu Zhang, Shihui Wang, Lu Liu, Qing Wang, Yufeng Liu, Yadong Yu, Qijin Zhai

Journal: Cell Mol Biol (Noisy-le-grand)

PubMed ID: 38372094

Doi: 10.14715/cmb/2024.70.1.27

Products & Services: Molecular Biology Reagents

Assessing the protection elicited by virus-like particles expressing the RSV pre-fusion F and tandem repeated G proteins against RSV rA2 line19F infection in mice

Authors: Min-Ju Kim, Ki Back Chu, Su-Hwa Lee, Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Eun-Kyung Moon, Fu-Shi Quan

Journal: Respir Res

PubMed ID: 38178222

Doi: 10.1186/s12931-023-02641-w

Products & Services: Codon Optimization

Chronic cortisol stimulation enhances hypothalamus-specific enrichment of metabolites in the rainbow trout brain

Authors: Ayelén M Blanco, Femilarani Antomagesh, Sara Comesaña, José L Soengas, Mathilakath M Vijayan

Journal: Am J Physiol Endocrinol Metab

PubMed ID: 38294699

Doi: 10.1152/ajpendo.00410.2023

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Spatial and Single-Cell Transcriptomics Reveal a Cancer-Associated Fibroblast Subset in HNSCC That Restricts Infiltration and Antitumor Activity of CD8+ T Cells

Authors: Chuwen Li, Haiyan Guo, Peisong Zhai, Ming Yan, Chun Liu, Xiaoning Wang, Chaoji Shi, Jiang Li, Tong Tong, Zhiyuan Zhang, Hailong Ma, Jianjun Zhang

Journal: Cancer Res

PubMed ID: 37930937

Doi: 10.1158/0008-5472.CAN-23-1448

Products & Services: Proteins, Expression, Isolation and Analysis

Tuning plasmid DNA amounts for cost-effective transfections of mammalian cells: when less is more

Authors: Aida Carreño, Rubén Guerrero-Yagüe, Enriqueta Casal, Rosa Mendoza, José Luis Corchero

Journal: Appl Microbiol Biotechnol

PubMed ID: 38212965

Doi: 10.1007/s00253-024-13003-x

Products & Services: Molecular Biology Reagents

Remodelling the inguinal adipose sensory system to switch on the furnace: Electroacupuncture stimulation induces brown adipose thermogenesis

Authors: Mengjiang Lu , Ziwei Yu , Xingyu Yang , Li An , Xinyue Jing , Tiancheng Xu , Mengqian Yuan , Bin Xu , Zhi Yu

Journal: Diabetes Obes Metab .

PubMed ID: 38229447

Doi: 10.1111/dom.15444

Products & Services: Proteins, Expression, Isolation and Analysis

LL‐37_Renalexin hybrid peptide exhibits antimicrobial activity at lower MICs than its counterpart single peptides

Authors: Julius Kwesi Narh , Nestor G Casillas-Vega , Xristo Zarate

Journal: Appl Microbiol Biotechnol .

PubMed ID: 38229302

Doi: 10.1007/s00253-023-12887-5

Products & Services: Gene Synthesis

High-Yield Expression and Purification of Scygonadin, an Antimicrobial Peptide, Using the Small Metal-Binding Protein SmbP

Authors: Jessica J. Gomez-Lugo 1 , Nestor G. Casillas-Vega , Alma Gomez-Loredo , Isaias Balderas-Renteria and Xristo Zarate

Journal: Microorganisms

Doi: 10.3390/microorganisms12020278

Products & Services: Gene Synthesis

Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain

Authors: Yanqun Wang, Zhaoyong Zhang, Minnan Yang, Xinyi Xiong, Qihong Yan, Lei Cao, Peilan Wei, Yuting Zhang, Lu Zhang, Kexin Lv, Jiantao Chen, Xuesong Liu, Xiaochu Zhao, Juxue Xiao, Shengnan Zhang, Airu Zhu, Mian Gan, Jingjun Zhang, Ruoxi Cai, Jianfen Zhuo, Yanjun Zhang, Haiyue Rao, Bin Qu, Yuanyuan Zhang, Lei Chen, Jun Dai, Linling Cheng, Qingtao Hu, Yaoqing Chen, Huibin Lv, Ray T Y So, Malik Peiris, Jingxian Zhao, Xiaoqing Liu, Chris Ka Pun Mok, Xiangxi Wang, Jincun Zhao

Journal: Cell Rep

PubMed ID: 38175758

Doi: 10.1016/j.celrep.2023.113653

Products & Services: Recombinant Proteins

The Development of a Rabies Virus-Vectored Vaccine against , Targeting BBI39

Authors: Shantel Rios, Bibek Bhattachan, Kruthi Vavilikolanu, Chrysoula Kitsou, Utpal Pal, Matthias J Schnell

Journal: Vaccines (Basel)

PubMed ID: 38250891

Doi: 10.3390/vaccines12010078

Products & Services: Recombinant Proteins

factor H-binding proteins are not required for serum resistance and infection in mammals

Authors: Nicholas A Cramer, Kalya M Socarras, Joshua Earl, Garth D Ehrlich, Richard T Marconi

Journal: Infect Immun

PubMed ID: 38289123

Doi: 10.1128/iai.00529-23

Products & Services: Codon Optimization

Structural role of K224 in taniborbactam inhibition of NDM-1

Authors: Daisuke Ono, Maria F Mojica, Christopher R Bethel, Yoshikazu Ishii, Salvador I Drusin, Diego M Moreno, Alejandro J Vila, Robert A Bonomo

Journal: Antimicrob Agents Chemother

PubMed ID: 38174924

Doi: 10.1128/aac.01332-23

Products & Services: Molecular Biology Reagents

Comparison of mouse models of microbial experience reveals differences in microbial diversity and response to vaccination

Authors: Autumn E Sanders, Henriette Arnesen, Frances K Shepherd, Dira S Putri, Jessica K Fiege, Mark J Pierson, Shanley N Roach, Harald Carlsen, David Masopust, Preben Boysen, Ryan A Langlois

Journal: mSphere

PubMed ID: 38286428

Doi: 10.1128/msphere.00654-23

Products & Services: Recombinant Proteins

Antibody reactive immunomes of and are diverse and defined by conformational antigenic determinants

Authors: Tian Luo, Jignesh G Patel, Xiaofeng Zhang, Jere W McBride

Journal: Front Cell Infect Microbiol

PubMed ID: 38264730

Doi: 10.3389/fcimb.2023.1321291

Products & Services: Catalog Peptides

Recombinantly expressed virus-like particles (VLPs) of canine circovirus for development of an indirect ELISA

Authors: Alison Neef, Babu Kanti Nath, Tridip Das, Daniel Luque, Jade K Forwood, Shane R Raidal, Shubhagata Das

Journal: Vet Res Commun

PubMed ID: 38163840

Doi: 10.1007/s11259-023-10290-z

Products & Services: Gene Synthesis

ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism

Authors: Edrees H Rashan, Abigail K Bartlett, Daven B Khana, Jingying Zhang, Raghav Jain, Andrew J Smith, Zakery N Baker, Taylor Cook, Alana Caldwell, Autumn R Chevalier, Brian F Pfleger, Peng Yuan, Daniel Amador-Noguez, Judith A Simcox, David J Pagliarini

Journal: biorxiv

PubMed ID: 38260250

Doi: 10.1101/2024.01.09.574893

Products & Services: Codon Optimization

Affinity-assisted covalent self-assembly of PduQ-SpyTag and Nox-SpyCatcher to construct multi-enzyme complexes on the surface of magnetic microsphere modified with chelated Ni

Authors: Mianxing Luo, Meng Zhang, Changbiao Chi, Guo Chen

Journal: Int J Biol Macromol

PubMed ID: 38218263

Doi: 10.1016/j.ijbiomac.2024.129365

Products & Services: Gene Synthesis

Comparative Analysis of Two NNMT Bisubstrate Inhibitors through Chemoproteomic Studies: Uncovering the Role of Unconventional SAM Analogue Moiety for Improved Selectivity

Authors: Ying Meng, Iredia D Iyamu, Noha A M Ahmed, Rong Huang

Journal: ACS Chem Biol

PubMed ID: 38181447

Doi: 10.1021/acschembio.3c00531

Products & Services: Proteins, Expression, Isolation and Analysis

A framework for Frizzled-G protein coupling and implications to the PCP signaling pathways

Authors: Zhibin Zhang , Xi Lin , Ling Wei , Yiran Wu , Lu Xu , Lijie Wu , Xiaohu Wei , Suwen Zhao, Xiangjia Zhu , Fei Xu

Journal: Cell Discov .

PubMed ID: 38182578

Doi: s41421-023-00627-y

Products & Services: Codon Optimization

Tomato-made edible COVID-19 vaccine TOMAVAC induces neutralizing IgGs in the blood sera of mice and humans

Authors: Zabardast T Buriev, Shukhrat E Shermatov, Dilshod E Usmanov, Mukhammadjon K Mirzakhmedov, Khurshida A Ubaydullaeva, Venera S Kamburova, Bakhtiyor K Rakhmanov, Mirzakamol S Ayubov, Adkham N Abdullaev

Journal: Front Nutr

PubMed ID: 38260078

Doi: 10.3389/fnut.2023.1275307

Products & Services: Gene Synthesis

Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice

Authors: Kaili Fu 1, Alvin Ho Kwan Cheung 2, Chi Chun Wong 1, Weixin Liu 1, Yunfei Zhou 1, Feixue Wang 1, Pingmei Huang 1, Kai Yuan 1, Olabisi Oluwabukola Coker 1, Yasi Pan 1, Danyu Chen 1, Nga Man Lam 3, Mengxue Gao 4, Xiang Zhang 1, He Huang 4, Ka Fai To 2, Joseph Jao Yiu Sung 5, Jun Yu

Journal: Cell

PubMed ID: 38295787

Doi: 10.1016/j.cell.2024.01.004

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Smart lattice light-sheet microscopy for imaging rare and complex cellular events

Authors: Yu Shi , Jimmy S Tabet , Daniel E Milkie , Timothy A Daugird , Chelsea Q Yang , Alex T Ritter , Andrea Giovannucci , Wesley R Legant

Journal: Nat Methods

PubMed ID: 38167656

Doi: 10.1038/s41592-023-02126-0

Products & Services: PCR Cloning and Subcloning

GDF15 linked to maternal risk of nausea and vomiting during pregnancy

Authors: M Fejzo # 1, N Rocha Cimino # 2, S M Lockhart # 2, C J Petry # 2, R G Kay 2 3, K Burling 2 4, P Barker 2 4, A L George 3, N Yasara 5, A Premawardhena 6 7, S Gong 8 9, E Cook 8, D Rimmington 2, K Rainbow 2, D J Withers 2, V Cortessis 10, P M Mullin 11, K W MacGibbon 12, E Jin, A Kam, A Campbell , O Polasek , G Tzoneva , F M Gribble , G S H Yeo , B Y H Lam , V Saudek, I A Hughes, K K Ong, J R B Perry , A Sutton Cole , M Baumgarten , P Welsh , N Sattar , G C S Smith , D S Charnock-Jones, A P Coll, C L Meek Mettananda , C Hayward, N Mancuso , S O'Rahilly

Journal: Nature

PubMed ID: 38092039

Doi: 10.1038/s41586-023-06921-9

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Circ_0087199 depletion attenuates lipopolysaccharides-induced human periodontal ligament cell injury through the miR-527/TLR4 axis

Authors: Jing Wang , Na Huo , Chuan Cai , Yu Zhang, Rui Xiao

Journal: Immunity

PubMed ID: 38270303

Doi: 10.1002/iid3.1153

Complement receptor 1 is the human erythrocyte receptor for erythrocyte binding protein

Authors: Seong-Kyun Lee, Cécile Crosnier, Paola Carolina Valenzuela-Leon, Brian L P Dizon, John P Atkinson, Jianbing Mu, Gavin J Wright, Eric Calvo, Karthigayan Gunalan, Louis H Miller

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38261617

Doi: 10.1073/pnas.2316304121

Products & Services: Molecular Biology Reagents

Multidimensional Optimization of for Carotenoid Overproduction

Authors: Jian Fan, Yang Zhang, Wenhao Li, Zhizhen Li, Danli Zhang, Qiwen Mo, Mingfeng Cao, Jifeng Yuan

Journal: Biodes Res

PubMed ID: 38213763

Doi: 10.34133/bdr.0026

Products & Services: PCR Cloning and Subcloning

A conserved protein inhibitor brings under check the activity of RNase E in cyanobacteria

Authors: Su-Juan Liu, Gui-Ming Lin, Yu-Qi Yuan, Wenli Chen, Ju-Yuan Zhang, Cheng-Cai Zhang

Journal: Nucleic Acids Res

PubMed ID: 38000383

Doi: 10.1093/nar/gkad1094

Products & Services: Proteins, Expression, Isolation and Analysis

Pharmacokinetic Analyses of a Lipid Nanoparticle-Encapsulated mRNA-Encoded Antibody against Rift Valley Fever Virus

Authors: Shuo Wang, Ziling Zhu, Jianmin Li

Journal: Mol Pharm

PubMed ID: 38295278

Doi: 10.1021/acs.molpharmaceut.3c01016

Products & Services: Proteins, Expression, Isolation and Analysis

Long chain capsaicin analogues synthetized by CALB-CLEAs show cytotoxicity on glioblastoma cell lines

Authors: Tania Diaz-Vidal, Vicente Paúl Armenta-Pérez, Luis Carlos Rosales-Rivera, Georgina Cristina Basulto-Padilla, Raúl Balam Martínez-Pérez, Juan Carlos Mateos-Díaz, Yanet K Gutiérrez-Mercado, Alejandro A Canales-Aguirre, Jorge A Rodríguez

Journal: Appl Microbiol Biotechnol

PubMed ID: 38217255

Doi: 10.1007/s00253-023-12856-y

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Functional characterization of the dimeric form of PDGF-derived fusion peptide fabricated based on theoretical arguments

Authors: Maryam Sadeghi-Ardebili, Sadegh Hasannia, Bahareh Dabirmanesh, Ramazan Ali Khavari-Nejad

Journal: Sci Rep

PubMed ID: 38200288

Doi: 10.1038/s41598-024-51707-2

Products & Services: Peptide Synthesis

A small-molecule activation mechanism that directly opens the KCNQ2 channel

Authors: Shaoying Zhang, Demin Ma, Kun Wang, Ya Li, Zhenni Yang, Xiaoxiao Li, Junnan Li, Jiangnan He, Lianghe Mei, Yangliang Ye, Zongsheng Chen, Juwen Shen, Panpan Hou, Jiangtao Guo, Qiansen Zhang, Huaiyu Yang

Journal: Nat Chem Biol

PubMed ID: 38167918

Doi: 10.1038/s41589-023-01515-y

Products & Services: Gene Synthesis

Ewing Sarcoma Related protein 1 recognizes R-loops by binding DNA forks

Authors: Michelle A Lay, Valery F Thompson, Ajibola D Adelakun, Jacob C Schwartz

Journal: biorxiv

PubMed ID: 38293191

Doi: 10.1101/2024.01.20.576463

Products & Services: Molecular Biology Reagents

The adc1 knockout with proC overexpression in Synechocystis sp PCC 6803 induces a diversion of acetyl-CoA to produce more polyhydroxybutyrate

Authors: Suthira Utharn, Saowarath Jantaro

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 38218963

Doi: 10.1186/s13068-024-02458-9

Products & Services: Proteins, Expression, Isolation and Analysis

A glycoside hydrolase 30 protein BpXynC of Bacillus paralicheniformis NMSW12 recognized as A MAMP triggers plant immunity response

Authors: Chenjie Yu, Xiaoli Liang, Yan Song, Qurban Ali, Xihao Yang, Linli Zhu, Qin Gu, Vladislav Kuptsov, Emilia Kolomiets, Huijun Wu, Xuewen Gao

Journal: Int J Biol Macromol

PubMed ID: 38286384

Doi: 10.1016/j.ijbiomac.2024.129750

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