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页码: 37/1072 每页显示数量

Confined Gel-Electromembrane Extraction of Oligonucleotides

Authors: Cong Liu, Jie Liu, Quan Liu, Qianyun Zhu, Hao Wang, Xiangming Fang, Wenfang Zhang, Zilong Liu, Chuixiu Huang

Journal: Analytical Chemistry

PubMed ID: 39078883

Doi: 10.1021/acs.analchem.4c02239

Products & Services: Custom DNA/RNA Oligos

Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures

Authors: Hongwei Zhang , Zhanxi Gu , Yuan Zeng , Yu Zhang

Journal: Structure

PubMed ID: 38870940

Doi: 10.1016/j.str.2024.05.013

Products & Services: Protein and Antibody Isolation

Integrative analysis of the therapeutic mechanisms of Astragaloside IV in idiopathic pulmonary fibrosis via network pharmacology and molecular validation

Authors: Shanshan Chen; Jin Yan; Jing Zhang; Yiwen Ma; Yiliang Su; Yiming Yu

Journal: Scientific REPORTS

PubMed ID: 41224967

Doi: 10.1038/s41598-025-23354-8

Products & Services: Protein Electrophoresis and Western

Integrative analysis of the therapeutic mechanisms of Astragaloside IV in idiopathic pulmonary fibrosis via network pharmacology and molecular validation

Authors: Shanshan Chen; Jin Yan; Jing Zhang; Yiwen Ma; Yiliang Su; Yiming Yu

Journal: Scientific REPORTS

PubMed ID: 41224967

Doi: 10.1038/s41598-025-23354-8

Products & Services: Protein Electrophoresis and Western

The strongest protein binder is surprisingly labile

Authors: Alba Fernandez-Calvo, Antonio Reifs, Laura Saa, Aitziber L Cortajarena, David De Sancho, Raul Perez-Jimenez

Journal: Protein Sci

PubMed ID: 38864696

Doi: 10.1002/pro.5030

Products & Services: Molecular Biology Reagents

Lytic transglycosylase Slt of Pseudomonas aeruginosa as a periplasmic hub protein

Authors: Luis F Avila-Cobian, Stefania De Benedetti, Hidekazu Hoshino, Van T Nguyen, Amr M El-Araby, Safaa Sader, Daniel D Hu, Sara L Cole, Choon Kim, Jed F Fisher, Matthew M Champion, Shahriar Mobashery

Journal: Protein Sci

PubMed ID: 38864725

Doi: 10.1002/pro.5038

Products & Services: Molecular Biology Reagents

Efficient Chemical Synthesis of Multi-Monoubiquitylated and Diubiquitylated Histones by the α-Halogen Ketone-Mediated Strategy

Authors: Shuai Peng, Xin Liu, Chengpiao Lu, Haibo Wang, Xiaotong Liu, Qingyue Gong, Huizhong Tao, Hongrui Xu, Changlin Tian, Guoqiang Xu, Jia-Bin Li

Journal: Bioconjugate Chemistry

PubMed ID: 38954775

Doi: 10.1021/acs.bioconjchem.4c00130

Products & Services: Gene Synthesis Codon Optimization Custom Vector Construction

Identification of endothelial protein C receptor as a novel druggable agonistic target for reendothelialization promotion and thrombosis prevention of eluting stent

Authors: Jing Chen , Changyi Zhou , Weilun Fang , Jiasheng Yin , Jian Shi , Junbo Ge , Li Shen , Shi-Ming Liu , Shao-Jun Liu

Journal: Bioactive Materials

Doi: doi.org/10.1016/j.bioactmat.2024.07.028

Products & Services: Peptide Synthesis

Fluorinated Titanium Oxide (TiO2-xFx) Nanospindles as Ultrasound-Triggered Pyroptosis Inducers to Boost Sonodynamic Immunotherapy

Authors: Shumin Sun , Xuan Huang , Nailin Yang , Huali Lei , Zifan Pei , Zhihui Han , Lin Liu , Fei Gong , Qiao Yu , Jingrui Li , Youdong Chen , Liang Cheng

Journal: ACS Nano

PubMed ID: 39010657

Doi: 10.1021/acsnano.4c05448

Products & Services: Protein and Antibody Isolation

Pooled CRISPRi screening reveals fungal-specific vulnerabilities across environments and genetic backgrounds

Authors: Lauren F Wensing; Philippe C Despr s; Desiree Francis; Meea Fogal; Anthony Hendriks; Nicholas C Gervais; Clara Fikry; Abdul-Rahman Adamu Bukari; Aleeza C Gerstein; Christina A Cuomo; Rebecca S Shapiro

Journal: biorxiv

PubMed ID: 41542621

Doi: 10.64898/2025.12.19.695556

Products & Services: DNA Sequencing

Design-driven optimization of low-cost reagent formulations for reproducible and high-yielding cell-free gene expression

Authors: Meagan L. Olsen; Caroline E. Copeland; Chad A. Sundberg; Rochelle Aw; Zachary M. Shaver; Govind Rao; James R. Swartz; Ashty S. Karim; Michael C. Jewett

Journal: Nature Communications

PubMed ID: 41786720

Doi: 10.1038/s41467-026-69605-8

Products & Services: ELISA Kits

Characterization of meiotic axis proteins in the model brown alga Ectocarpus

Authors: Emma I Kane; Lioba S Trefs; Lena Eckert; Susana M Coelho; John R Weir

Journal: EMBO Reports

PubMed ID: 41131160

Doi: 10.1038/s44319-025-00605-3

Characterization of meiotic axis proteins in the model brown alga Ectocarpus

Authors: Emma I Kane; Lioba S Trefs; Lena Eckert; Susana M Coelho; John R Weir

Journal: EMBO Reports

PubMed ID: 41131160

Doi: 10.1038/s44319-025-00605-3

Chlorinated bis-4-hydroxycoumarins suppress flavivirus replication by inhibiting dengue virus type 2 translation and replication

Authors: Naphat Loeanurit; Thi-Hong-Truc Phan; Kowit Hengphasatporn; Thanchanok Chanachanvong; Borwornlak Toopradab; Phornphimon Maitarad; Prangwalai Chanchaem; Vorthon Sawaswong; Sunchai Payungporn; Ajirawadee Suwanchan; Auwal Rabiu Auwal; Kittikhun Wangkanont; Thanyada Rungrotmongkol; Yasuteru Shigeta; Tanatorn Khotavivattana; Warinthorn Chavasiri; Siwaporn Boonyasuppayakorn

Journal: Scientific REPORTS

PubMed ID: 41545435

Doi: 10.1038/s41598-026-35654-8

Products & Services: Plasmid DNA Preparation

Chlorinated bis-4-hydroxycoumarins suppress flavivirus replication by inhibiting dengue virus type 2 translation and replication

Journal: Scientific REPORTS

PubMed ID: 41545435

Doi: 10.1038/s41598-026-35654-8

Products & Services: Plasmid DNA Preparation

Chlorinated bis-4-hydroxycoumarins suppress flavivirus replication by inhibiting dengue virus type 2 translation and replication

Journal: Scientific REPORTS

PubMed ID: 41545435

Doi: 10.1038/s41598-026-35654-8

Products & Services: Plasmid DNA Preparation

Design-driven optimization of low-cost reagent formulations for reproducible and high-yielding cell-free gene expression

Authors: Meagan L. Olsen; Caroline E. Copeland; Chad A. Sundberg; Rochelle Aw; Zachary M. Shaver; Govind Rao; James R. Swartz; Ashty S. Karim; Michael C. Jewett

Journal: Nature Communications

PubMed ID: 41786720

Doi: 10.1038/s41467-026-69605-8

Products & Services: ELISA Kits

Improvement and application of vacuum-infiltration system in tomato

Authors: Xinghao Yao, Ayat Taheri, Hang Liu, Yaojie Zhang, Ling Li, Jin Shao, Ke Wu, Qing Miao, Weizhi He, Xinyi Hu, Kexuan Tang

Journal: Horticulture research

Doi: doi.org/10.1093/hr/uhae197

Products & Services: Plasmid DNA Preparation

Engineering psychrophilic polymerase for nanopore long-read sequencing

Authors: Yaping Sun , Danny Hsu Ko , Jie Gao , Kang Fu , Yuanchen Mao , Yun He , Hui Tian

Journal: Front Bioeng Biotechnol

PubMed ID: 39011153

Doi: 10.3389/fbioe.2024.1406722

Products & Services: PCR Cloning and Subcloning

Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection

Authors: Michael J Peluso, Dylan Ryder, Robert R Flavell, Yingbing Wang, Jelena Levi, Brian H LaFranchi, Tyler-Marie Deveau, Amanda M Buck, Sadie E Munter, Kofi A Asare, Maya Aslam, Walter Koch, Gyula Szabo, Rebecca Hoh, Monika Deswal, Antonio E Rodriguez, Melissa Buitrago, Viva Tai, Uttam Shrestha, Scott Lu, Sarah A Goldberg, Thomas Dalhuisen, Joshua J Vasquez, Matthew S Durstenfeld, Priscilla Y Hsue, J Daniel Kelly, Nitasha Kumar, Jeffrey N Martin, Aruna Gambhir, Ma Somsouk, Youngho Seo, Steven G Deeks, Zoltan G Laszik, Henry F VanBrocklin, Timothy J Henrich

Journal: Sci Transl Med

PubMed ID: 38959327

Doi: 10.1126/scitranslmed.adk3295

Products & Services: Molecular Biology Reagents

Force-regulated chaperone activity of BiP/ERdj3 is opposite to their homologs DnaK/DnaJ

Authors: Souradeep Banerjee, Debojyoti Chowdhury, Soham Chakraborty, Shubhasis Haldar

Journal: Protein Sci

PubMed ID: 38864739

Doi: 10.1002/pro.5068

Products & Services: Molecular Biology Reagents

Fit-for-purpose heterodivalent single-domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile

Authors: Everardo R Rodriguez Rodriguez, Rune Thorbjørn Nordvang, Marcus Petersson, Jakob Kræmmer Haar Rendsvig, Emma Wenzel Arendrup, Monica L Fernández Quintero, Timothy P Jenkins, Andreas H Laustsen, Sandra Wingaard Thrane

Journal: Protein Sci

PubMed ID: 38923049

Doi: 10.1002/pro.5035

Products & Services: Protein and Antibody Isolation

Development of a microbial dewaxing agent using three spore forming bacteria

Authors: Xiaoyan Guo; Xutao Zhao; Lizhu Li; Haibo Jin; Jianjun Wang

Journal: Bioresources and Bioprocessing

PubMed ID: 39115754

Doi: 10.1186/s40643-024-00795-z

Products & Services: Gene Synthesis

In silico advancements in Peptide-MHC interaction: A molecular dynamics study of predicted glypican-3 peptides and HLA-A*11:01

Authors: Thaweesak Chieochansin; Kamonpan Sanachai; Nitchakan Darai; Wannasiri Chiraphapphaiboon; Kornkan Choomee; Pa-thai Yenchitsomanus; Chanitra Thuwajit; Thanyada Rungrotmongkol

Journal: Heliyon

PubMed ID: 39263056

Doi: 10.1016/j.heliyon.2024.e36654

Products & Services: Peptide Synthesis

Optimizing the Design and Geometry of T Cell-Engaging Bispecific Antibodies Targeting CEA in Colorectal Cancer

Authors: Abdullah Elsayed, Louis Plüss, Larissa Nideroest, Giulia Rotta, Marina Thoma, Nathan Zangger, Frederik Peissert, Stefanie K Pfister, Christian Pellegrino, Sheila Dakhel Plaza, Roberto De Luca, Markus G Manz, Annette Oxenius, Emanuele Puca, Cornelia Halin, Dario Neri

Journal: Mol Cancer Ther

PubMed ID: 38638035

Doi: 10.1158/1535-7163.MCT-23-0766

Products & Services: Gene Synthesis

The adaptor protein ECAP, the corepressor LEUNIG, and the transcription factor BEH3 interact and regulate microsporocyte generation in Arabidopsis

Authors: Lei Shi, Changjiang Li, Gaofeng Lv, Xing Li, Wutao Feng, Yujing Bi, Wenhui Wang, Youqun Wang, Lei Zhu, Wenqiang Tang, Ying Fu

Journal: Plant Cell

PubMed ID: 38526222

Doi: 10.1093/plcell/koae086

Products & Services: Gene Synthesis

Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system

Authors: Danping Zhang 1, Liyang Du 1, Haishan Gao 2 3, Cai Yuan 4, Zhonghui Lin 1

Journal: Nucleic Acids Res

PubMed ID: 38967023

Doi: 10.1093/nar/gkae569

Products & Services: Gene Synthesis

Evaluation of combination vaccines targeting transmission of Plasmodium falciparum and P. vivax

Authors: Yi Cao 1, Clifford T H Hayashi , Maisa da Silva Araujo , Abhai K Tripathi , Alice Oliveira Andrade , Jansen Fernandes Medeiros , Joseph Vinetz & Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39033079

Doi: 10.1016/j.vaccine.2024.07.041

Products & Services: Codon Optimization

Amplification editing enables efficient and precise duplication of DNA from short sequence to megabase and chromosomal scale

Authors: Ruiwen Zhang , Zhou He , Yajing Shi , Xiangkun Sun , Xinyu Chen , Guoquan Wang , Yizhou Zhang , Pan Gao , Ying Wu , Shuhan Lu , Junyi Duan , Shangwu Sun , Na Yang , Wei Fan , Kaitao Zhao , Bei Yang , Yuchen Xia , Yan Zhang , Ying Zhang , Hao Yin

Journal: Cell

PubMed ID: 38936359

Doi: 10.1016/j.cell.2024.05.056

Products & Services: Custom RNAi Services

Mechanisms Ensuring Fidelity of Family X DNA Polymerases in Programmed DNA rearrangements in Paramecium tetraurelia

Authors: Antonin Nourisson, Sophia Missoury, Ahmed Haouz, Marc Delarue

Journal: biorxiv

Doi: 2024.07.26.605286

Products & Services: Gene Synthesis

Cytochrome b5 diversity in green lineages preceded the evolution of syringyl lignin biosynthesis

Authors: Xianhai Zhao, Yunjun Zhao, Qing-Yin Zeng, Chang-Jun Liu

Journal: Plant Cell

PubMed ID: 38657101

Doi: 10.1093/plcell/koae120

Products & Services: Gene Synthesis

A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease

Authors: Kai S. Yang; Lauren R. Blankenship; Syuan-Ting Alex Kuo; Yan J. Sheng; Pingwei Li; Carol A. Fierke; David H. Russell; Xin Yan; Shiqing Xu; Wenshe Ray Liu

Journal: ACS Chemical Biology

PubMed ID: 36629751

Doi: 10.1021/acschembio.2c00695

Products & Services: Protein and Antibody Isolation

In silico advancements in Peptide-MHC interaction: A molecular dynamics study of predicted glypican-3 peptides and HLA-A*11:01

Authors: Thaweesak Chieochansin; Kamonpan Sanachai; Nitchakan Darai; Wannasiri Chiraphapphaiboon; Kornkan Choomee; Pa-thai Yenchitsomanus; Chanitra Thuwajit; Thanyada Rungrotmongkol

Journal: Heliyon

PubMed ID: 39263056

Doi: 10.1016/j.heliyon.2024.e36654

Products & Services: Peptide Synthesis

A Novel Y-Shaped, S-O-N-O-S-Bridged Crosslink between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease

Authors: Kai S. Yang; Lauren R. Blankenship; Syuan-Ting Alex Kuo; Yan J. Sheng; Pingwei Li; Carol A. Fierke; David H. Russell; Xin Yan; Shiqing Xu; Wenshe Ray Liu

Journal: ACS Chemical Biology

PubMed ID: 36629751

Doi: 10.1021/acschembio.2c00695

Products & Services: Protein and Antibody Isolation

An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern

Authors: Wenjuan Du; Daniel L. Hurdiss; Dubravka Drabek; Anna Z. Mykytyn; Franziska K. Kaiser; Mariana Gonz lez-Hern ndez; Diego Mu oz-Santos; Mart M. Lamers; Rien van Haperen; Wentao Li; Ieva Drulyte; Chunyan Wang; Isabel Sola; Federico Armando; Georg Beythien; Malgorzata Ciurkiewicz; Wolfgang Baumg rtner; Kate Guilfoyle; Tony Smits; Joline van der Lee; Frank J.M. van Kuppeveld; Geert van Amerongen; Bart L. Haagmans; Luis Enjuanes; Albert D.M.E. Osterhaus; Frank Grosveld; Berend-Jan Bosch

Journal: Science immunology

PubMed ID: 35471062

Doi: 10.1126/sciimmunol.abp9312

Acceptors stability modulates the efficiency of post-translational protein N-glycosylation

Authors: Paula M Couto, Carlos M A Guardia, Facundo L Couto, Carlos A Labriola, María S Labanda, Julio J Caramelo

Journal: FASEB J

PubMed ID: 38934375

Doi: 10.1096/fj.202302267R

Products & Services: Protein and Antibody Isolation Gene Synthesis

Mechanism of ceramide synthase inhibition by fumonisin B1

Authors: Zike Zhang 1 2 4, Qi Fang 1 2 4, Tian Xie 1 2, Xin Gong

Journal: Structure

Doi: 10.1016/j.str.2024.06.002

Products & Services: Protein and Antibody Isolation

Regulatory Peptide Encoded by the Primary Transcript of miR396a Influences Gene Expression and Root Development in Solanum lycopersicum

Authors: Zhengjie Wang, Ruili Lv, Chenglin Su, Yan Li, Sizhe Fang, Ruirui Yang, Jiaxuan Zhu, Ruiming Wang, Jun Meng, Yushi Luan

Journal: J Agric Food Chem

PubMed ID: 38994823

Doi: 10.1021/acs.jafc.4c03588

Products & Services: Peptide Synthesis

Impact of Equilibrative Nucleoside Transporters TgAT1, TgENT1, and TgENT3 on Toxoplasma gondii Infection and Differentiation

Authors: Amber Goerner, Gabriel Messina, Lea Drogalis Beckham, Bruno Martorelli Di Genova

Journal: biorxiv

Doi: doi.org/10.1101/2024.07.10.601519

Products & Services: Gene Synthesis

Comparative biochemistry of PET hydrolase-carbohydrate-binding module fusion enzymes on a variety of PET substrates

Authors: Andrew Philip Rennison , Andreas Prestel , Peter Westh , Marie Sofie Møller

Journal: Enzyme and Microbial Technology

PubMed ID: 39047349

Doi: 10.1016/j.enzmictec.2024.110479

Products & Services: Gene Synthesis Mutagenesis Services

Discovery of antimicrobial peptides clostrisin and cellulosin from Clostridium: insights into their structures, co-localized biosynthetic gene clusters, and antibiotic activity

Authors: Moisés Alejandro Alejo Hernandez , Katia Pamela Villavicencio Sánchez , Rosendo Sánchez Morales , Karla Georgina Hernández-Magro Gil, David Silverio Moreno-Gutiérrez , Eddie Guillermo Sanchez-Rueda , Yanet Teresa-Cruz , Brian Choi, Armando Hernández Garcia , Alba Romero-Rodríguez, Oscar Juárez , Siseth Martínez-Caballero , Mario Figueroa , Corina-Diana Ceapă

Journal: Beilstein Journal of Organic Chemistry

PubMed ID: 39109298

Doi: 10.3762/bjoc.20.159

Products & Services: Gene Synthesis

Integration of validated functional evidence to support the pathogenicity of KCNH2 variants

Authors: Reema W Aljassar, Qianyi Shen, Buthaina Albash, Jamie I Vandenberg, Mohammad A Ebrahim, Chai-Ann Ng

Journal: Genet Med Open

PubMed ID: 39669639

Doi: 10.1016/j.gimo.2024.101868

Products & Services: Gene Synthesis

Development of a microbial dewaxing agent using three spore forming bacteria

Authors: Xiaoyan Guo; Xutao Zhao; Lizhu Li; Haibo Jin; Jianjun Wang