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Discovery of Two Novel Immunoepitopes and Development of Peptide-based Sarcoidosis Immunoassay

Authors: Changya Peng , Jaya Talreja , Brennen Steinbauer , Kazuhiko Shinki , Laura L Koth , Lobelia Samavati

Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PubMed ID: 38385694

Doi: 10.1164/rccm.202306-1054OC

Products & Services: Peptide Synthesis Polyclonal Antibody Services

An Antioxidative and Active Shrinkage Hydrogel Integratedly Promotes Re-Epithelization and Skin Constriction for Enhancing Wound Closure

Authors: Jiacheng Sun, Wang Jia, Hedong Qi, Jiawei Huo, Xiaodan Liao, Yuan Xu, Jun Wang, Zihao Sun, Yang Liu, Jingchao Liu, Mingming Zhen, Chunru Wang, Chunli Bai

Journal: Adv Mater

PubMed ID: 38332741

Doi: 10.1002/adma.202312440

Products & Services: Proteins, Expression, Isolation and Analysis

Essential functions of Inositol hexakisphosphate (IP6) in Murine Leukemia Virus replication

Authors: Banhi Biswas, Kin Kui Lai, Harrison Bracey, Siddhartha A K Datta, Demetria Harvin, Gregory A Sowd, Christopher Aiken, Alan Rein

Journal: biorxiv

PubMed ID: 38464197

Doi: 10.1101/2024.02.27.581940

Products & Services: Proteins, Expression, Isolation and Analysis

Architecture and flexibility of native kinetochores revealed by structural studies utilizing a thermophilic yeast

Authors: Daniel J Barrero, Sithara S Wijeratne, Xiaowei Zhao, Grace F Cunningham, Yan Rui, Christian R Nelson, Arimura Yasuhiro, Hironori Funabiki, Charles L Asbury, Zhiheng Yu, Radhika Subramanian, Sue Biggins

Journal: biorxiv

PubMed ID: 38464254

Doi: 10.1101/2024.02.28.582571

Products & Services: Recombinant Proteins

Unveiling PET Hydrolase Surface Dynamics through Fluorescence Microscopy

Authors: A P Rennison, A Nousi, P Westh, R Marie, M S Møller

Journal: Chembiochem

PubMed ID: 38224131

Doi: 10.1002/cbic.202300661

Products & Services: Molecular Biology Reagents

NY-ESO-1-specific T cell receptor-engineered T cells and Tranilast, a TRPV2 antagonist bivalent treatment enhances the killing of esophageal cancer: a dual-targeted cancer therapeutic route

Authors: Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang, Rongqi Huang, Zhiyuan Li

Journal: Cancer Cell Int

PubMed ID: 38336680

Doi: 10.1186/s12935-024-03249-w

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CD39 tumor infiltrating T cells from colorectal cancers exhibit dysfunctional phenotype

Authors: Yuan Feng, Xin Xu, Jiaxin Zhang, Christopher Sanderson, Jun Xia, Zhang Bu, Yili Yang, Peng Yang, Zhiliang Lu

Journal: Am J Cancer Res

PubMed ID: 38455401

Doi: 10.62347/IZEN3736

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Exploring the ATG9A interactome uncovers interaction with VPS13A

Authors: Alexander R van Vliet, Harold B J Jefferies, Peter A Faull, Jessica Chadwick, Fairouz Ibrahim, Mark J Skehel, Sharon A Tooze

Journal: J Cell Sci

PubMed ID: 38294121

Doi: 10.1242/jcs.261081

Products & Services: Proteins, Expression, Isolation and Analysis

A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency

Authors: Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl, Alana Rainbow-Fletcher, Paul Getty, Ian Anderson, Niall Barron, Jonathan Bones

Journal: Int J Mol Sci

PubMed ID: 38474031

Doi: 10.3390/ijms25052785

Products & Services: Codon Optimization

Seroprevalence of IgM/IgG and Neutralizing Antibodies against SARS-CoV-2 in Unvaccinated Young Adults from Mexico Who Reported Not Having Had a Previous COVID-19 Infection

Authors: Diana Lourdes Padilla-Bórquez, Mónica Guadalupe Matuz-Flores, Jorge Hernández-Bello, Gabriela Athziri Sánchez-Zuno, Samuel García-Arellano, Edith Oregon-Romero, Melva Guadalupe Herrera-Godina, Guillermo González-Estevez, Norma Patricia Adan-Bante, Jesús Alfredo Rosas-Rodríguez, José Francisco Muñoz-Valle

Journal: Can J Infect Dis Med Microbiol

PubMed ID: 38384428

Doi: 10.1155/2024/8871439

Products & Services: Proteins, Expression, Isolation and Analysis

ANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathway

Authors: Jiaqi Xu, Fei Wu, Yue Zhu, Tiantian Wu, Tianyue Cao, Wenxin Gao, Meng Liu, Weifeng Qian, Guannan Feng, Xiaoxue Xi, Shunyu Hou

Journal: Cancer Cell Int

PubMed ID: 38311733

Doi: 10.1186/s12935-024-03246-z

Products & Services: Proteins, Expression, Isolation and Analysis

The 3-hydroxyacyl-CoA dehydratase 1/2 form complex with trans-2-enoyl-CoA reductase involved in substrates transfer in very long chain fatty acid elongation

Authors: Youli Zhou, Rui Lv, Richard D Ye, Ruobing Ren, Leiye Yu

Journal: Biochem Biophys Res Commun

PubMed ID: 38422897

Doi: 10.1016/j.bbrc.2024.149588

Products & Services: Proteins, Expression, Isolation and Analysis

Plum blossom low molecular weight polypeptide protects HaCaT cells against UVB-induced oxidative damage in vitro and underlying mechanism

Authors: Zhixiong Chen, Ping Cao, Tingheng Zhu, Cui Yan, Zhongbo Zheng, Hong Yao

Journal: Skin Res Technol

PubMed ID: 38282275

Doi: 10.1111/srt.13582

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Efficient Expression and Characterization of an Endo-Type Lyase HCLase_M28 and Its Gradual Scale-Up Fermentation for the Preparation of Chondroitin Sulfate Oligosaccharides

Authors: Ruibao Ju, Baoqin Han, Feng Han, Yanfei Peng

Journal: Appl Biochem Biotechnol

PubMed ID: 38386140

Doi: 10.1007/s12010-024-04878-7

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Recombinant Rod Domain of Vimentin Reduces SARS-CoV-2 Viral Replication by Blocking Spike Protein-ACE2 Interactions

Authors: Fong Wilson Lam, Cameron August Brown, Shannon Elizabeth Ronca

Journal: Int J Mol Sci

PubMed ID: 38473724

Doi: 10.3390/ijms25052477

Products & Services: Molecular Biology Reagents

Bicistronic expression of nuclear transgenes in Chlamydomonas reinhardtii

Authors: Nick Jacobebbinghaus, Kyle J Lauersen, Olaf Kruse, Thomas Baier

Journal: the plant journal

PubMed ID: 38415961

Doi: 10.1111/tpj.16677

Products & Services: Gene Synthesis

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Authors: Leon Tejwani, Neal G Ravindra, Changwoo Lee, Yubao Cheng, Billy Nguyen, Kimberly Luttik, Luhan Ni, Shupei Zhang, Logan M Morrison, John Gionco, Yangfei Xiang, Jennifer Yoon, Hannah Ro, Fatema Haidery, Rosalie M Grijalva, Eunwoo Bae, Kristen Kim , Regina T Martuscello, Harry T Orr, Huda Y Zoghbi , Hayley S McLoughlin, Laura P W Ranum, Vikram G Shakkottai, Phyllis L Faust, Siyuan Wang, David van Dijk, Janghoo Lim

Journal: Neuron

PubMed ID: 38016472

Doi: 10.1016/j.neuron.2023.10.039

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Discoveries of GPR39 as an evolutionarily conserved receptor for bile acids and of its involvement in biliary acute pancreatitis

Authors: Zhentao Zi 1 2, Yi Rao

Journal: Sci Adv

PubMed ID: 38306436

Doi: 10.1126/sciadv.adj0146

Products & Services: Gene Synthesis

Examination of SARS-CoV-2 serological test results from multiple commercial and laboratory platforms with an in-house serum panel

Authors: Sandra N Lester, Megan Stumpf, Brandi D Freeman, Lisa Mills, Jarad Schiffer, Vera Semenova, Tao Jia, Rita Desai, Peter Browning, Bailey Alston, Muyiwa Ategbole, Shanna Bolcen, Alexander Chen, Ebenezer David, Panagiotis Manitis, Heather Tatum, Yunlong Qin, Briana Zellner, Jan Drobeniuc, Alexandra Tejada-Strop, Payel Chatterjee, Punya Shrivastava-Ranjan, M Harley Jenks, Laura K McMullan, Mike Flint, Christina F Spiropoulou, Glenn P Niemeyer, Bonnie J Werner, Christopher J Bean, Jeffrey A Johnson, Alex R Hoffmaster, Panayampalli S Satheshkumar, Amy J Schuh, S Michele Owen, Natalie J Thornburg

Journal: Access Microbiol

PubMed ID: 38482357

Doi: 10.1099/acmi.0.000463.v4

Products & Services: Proteins, Expression, Isolation and Analysis

Efficient production of 2'-fucosyllactose from fructose through metabolically engineered recombinant Escherichia coli

Authors: Ran You, Lei Wang, Meirong Hu, Yong Tao

Journal: Microb Cell Fact

PubMed ID: 38303005

Doi: 10.1186/s12934-024-02312-5

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The expression of genes encoding novel Sesame oleosin variants facilitates enhanced triacylglycerol accumulation in Arabidopsis leaves and seeds

Authors: Sanket Anaokar, Yuanxue Liang, Xiao-Hong Yu, Yingqi Cai, Yuanheng Cai, John Shanklin

Journal: New Phytol

PubMed ID: 38329350

Doi: 10.1111/nph.19548

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Phospho-eIF4E stimulation regulates coronavirus entry by selective expression of cell membrane-residential factors

Authors: Xiu-Zhong Zhang, Jing Wang, Wen-Jun Tian, Jing-Ling You, Xiao-Jing Chi, Xiao-Jia Wang

Journal: J Virol

PubMed ID: 38299843

Doi: 10.1128/jvi.01948-23

Products & Services: Gene Synthesis

Distinct structural variants and repeat landscape shape the genomes of the ancient grapes Aglianico and Falanghina

Authors: Riccardo Aversano, Marina Iovene , Salvatore Esposito , Alberto L'Abbate , Clizia Villano , Ermanno Di Serio , Maria Francesca Cardone , Carlo Bergamini , Riccardo Aiese Cigliano , Vincenzo D'Amelia , Luigi Frusciante , Domenico Carputo

Journal: BMC Plant Biol.

PubMed ID: 38317087

Doi: 10.1186/s12870-024-04778-2

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Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1

Authors: Xiangwei Wu, Yunxiang Du, Lu-Jun Liang, Ruichao Ding, Tianyi Zhang, Hongyi Cai, Xiaolin Tian, Man Pan, Lei Liu

Journal: Nat Commun .

PubMed ID: 38341401

Doi: 10.1038/s41467-024-45635-y

Products & Services: Gene Synthesis

Mage Transposon: A Novel Gene Delivery System for Mammalian Cells

Authors: Jinghan Tian, Doudou Tong, Zhendong Li, Erqiang Wang, Yifei Yu, Hangya Lv, Zhendan Hu, Fang Sun, Guoping Wang, Min He, Tian Xia

Journal: Nucleic Acids Res .

PubMed ID: 38300794

Doi: 10.1093/nar/gkae048

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An oncolytic virus–T cell chimera for cancer immunotherapy

Authors: Yuxuan Chen , Xiaohong Chen , Weier Bao , Gang Liu , Wei Wei , Yuan Ping

Journal: Nat Biotechnol .

PubMed ID: 38336902

Doi: 10.1038/s41587-023-02118-7

Products & Services: Recombinant Proteins

A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection

Authors: Lorena M Coria , Juan Manuel Rodriguez , Agostina Demaria , Laura A Bruno , Mayra Rios Medrano , Celeste Pueblas Castro , Eliana F Castro , Sabrina A Del Priore , Andres C Hernando Insua , Ingrid G Kaufmann , Lucas M Saposnik , William B Stone , Lineia Prado , Ulises S Notaro , Ayelen N Amweg , Pablo U Diaz , Martin Avaro , Hugo Ortega , Ana Ceballos , Valeria Krum , Francisco M Zurvarra , Johanna E Sidabra , Ignacio Drehe , Jonathan A Baqué , Mariana Li Causi , Analia V De Nichilo , Cristian J Payes , Teresa Southard , Julio C Vega , Albert J Auguste , Diego E Álvarez , Juan M Flo , Karina A Pasquevich , Juliana Cassataro

Journal: Nat Commun

PubMed ID: 38307851

Doi: 10.1038/s41467-024-45180-8

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The chromatin-associated lncREST ensures effective replication stress response by promoting the assembly of fork signaling factors

Authors: Luisa Statello , José Miguel Fernandez-Justel , Jovanna González , Marta Montes , Alessia Ranieri , Enrique Goñi , Aina M Mas , Maite Huarte

Journal: Nat Commun

PubMed ID: 38302450

Doi: 10.1038/s41467-024-45183-5

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A Cancer Nanovaccine for Co-Delivery of Peptide Neoantigens and Optimized Combinations of STING and TLR4 Agonists

Authors: Jessalyn J. Baljon, Alexander J. Kwiatkowski, Hayden M. Pagendarm, Payton T. Stone, Amrendra Kumar, Vijaya Bharti, Jacob A. Schulman, Kyle W. Becker, Eric W. Roth, Plamen P. Christov, Sebastian Joyce, and John T. Wilson*

Journal: ACS Nano

PubMed ID: 38386282

Doi: 10.1021/acsnano.3c04471

Products & Services: Peptide Synthesis

Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA. 2.86 and FLip variants

Authors: Panke Qu 1, Kai Xu 1, Julia N Faraone 2, Negin Goodarzi 1, Yi-Min Zheng 1, Claire Carlin 3, Joseph S Bednash 4, Jeffrey C Horowitz 4, Rama K Mallampalli 4, Linda J Saif 5, Eugene M Oltz 6, Daniel Jones 7, Richard J Gumina 8, Shan-Lu Liu

Journal: Cell

PubMed ID: 38194968

Doi: 10.1016/j.cell.2023.12.026

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SPR spectroscopic analysis of myosin binding to wild type and mutant UNC45B

Authors: Silvana Valdebenito, Eliseo Eugenin, Andres Oberhauser

Journal: MicroPubl Biol

PubMed ID: 38404916

Doi: 10.17912/micropub.biology.001131

Products & Services: Recombinant Proteins

Imaging of extracellular and intracellular ATP in pancreatic beta cells reveals correlation between glucose metabolism and purinergic signalling

Authors: Seyed M Ghiasi, Nynne M Christensen, Per A Pedersen, Emil Z Skovhøj, Ivana Novak

Journal: Cell Signal

PubMed ID: 38373668

Doi: 10.1016/j.cellsig.2024.111109

Products & Services: Proteins, Expression, Isolation and Analysis

Chimeric antigen receptor T cells targeting the GM3(Neu5Gc) ganglioside

Authors: Julia Heinzelbecker, Marte Fauskanger, Ida Jonson, Ute Krengel, Geir Åge Løset, Ludvig Munthe, Anders Tveita

Journal: Front Immunol

PubMed ID: 38370401

Doi: 10.3389/fimmu.2024.1331345

Products & Services: Gene Synthesis

Long noncoding RNA ABHD11-AS1 interacts with SART3 and regulates CD44 RNA alternative splicing to promote lung carcinogenesis

Authors: Po-Shun Wang, Zulong Liu, Osama Sweef, Jie Xie, Jing Chen, Haining Zhu, Patti C Zeidler-Erdely, Chengfeng Yang, Zhishan Wang

Journal: Environ Int

PubMed ID: 38364571

Doi: 10.1016/j.envint.2024.108494

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KNL1 and NDC80 represent new universal markers for the detection of functional centromeres in plants

Authors: Ludmila Oliveira, Pavel Neumann, Yennifer Mata-Sucre, Yi-Tzu Kuo, André Marques, Veit Schubert, Jiří Macas

Journal: Chromosome Res

PubMed ID: 38403686

Doi: 10.1007/s10577-024-09747-x

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Supplementation of citrus pectin with whole-cell pectinase PG5 on Pichia pastoris promotes recovery of colitis and enhances intestinal barrier function in DSS-treated mice

Authors: Li Zhang, Jing Ren, Tianfei Yu, Yuanrong Li, Yanshun Li, Shuang Lu, Xiaohua Guo

Journal: Int J Biol Macromol

PubMed ID: 38428761

Doi: 10.1016/j.ijbiomac.2024.130476

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Precise fine-turning of GhTFL1 by base editing tools defines ideal cotton plant architecture

Authors: Guanying Wang, Fuqiu Wang, Zhongping Xu, Ying Wang, Can Zhang, Yi Zhou, Fengjiao Hui, Xiyan Yang, Xinhui Nie, Xianlong Zhang, Shuangxia Jin

Journal: Genome Biol

PubMed ID: 38409014

Doi: 10.1186/s13059-024-03189-8

Design and development of multiepitope chimeric antigens by bioinformatic and bacterial based recombinant expression methods, with potential application for bovine tuberculosis serodiagnosis

Authors: Cassiano Martin Batista, Josir Laine Veschi, Vanessa Felipe de Souza, Leonardo Foti, Lea Chapaval Andri

Journal: Vet Immunol Immunopathol

PubMed ID: 38377627

Doi: 10.1016/j.vetimm.2024.110729

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Functional analyses of TRAF6 gene in Argopecten scallops

Authors: Xiaotong Zhang, Xia Wang, Jieyu Chen, Min Chen, Xia Lu, Junhao Ning, Haijun Liu, Guilong Liu, Xin Xu, Xiaoxu Qu, Kai Yu, He Xu, Chunde Wang, Bo Liu

Journal: Fish Shellfish Immunol

PubMed ID: 38354964

Doi: 10.1016/j.fsi.2024.109443

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Deficiency in PHD2-mediated hydroxylation of HIF2α underlies Pacak-Zhuang syndrome

Authors: Fraser G Ferens, Cassandra C Taber, Sarah Stuart, Mia Hubert, Daniel Tarade, Jeffrey E Lee, Michael Ohh

Journal: Commun Biol

PubMed ID: 38418569

Doi: 10.1038/s42003-024-05904-4

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Crossprotection induced by virus-like particles containing influenza dual-hemagglutinin and M2 ectodomain

Authors: Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Min-Ju Kim, Ki-Back Chu, Hae-Ji Kang, Fu-Shi Quan

Journal: Nanomedicine (Lond)

PubMed ID: 38390688

Doi: 10.2217/nnm-2023-0353

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Establishment of a Dual-Vector System for Gene Delivery Utilizing Prototype Foamy Virus

Authors: Soo-Yeon Cho, Yoon Jae Lee, Seong-Mook Jung, Young Min Son, Cha-Gyun Shin, Eui Tae Kim, Kyoung-Dong Kim

Journal: J Microbiol Biotechnol

PubMed ID: 38379304

Doi: 10.4014/jmb.2312.12026

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A diffusible small-RNA-based Turing system dynamically coordinates organ polarity

Authors: Emanuele Scacchi, Gael Paszkiewicz, Khoa Thi Nguyen, Shreyas Meda, Agata Burian, Walter de Back, Marja C P Timmermans

Journal: Nat Plants

PubMed ID: 38409292

Doi: 10.1038/s41477-024-01634-x

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Long-Term Dynamic Changes in Hybrid Immunity over Six Months after Inactivated and Adenoviral Vector Vaccination in Individuals with Previous SARS-CoV-2 Infection

Authors: Nungruthai Suntronwong, Sitthichai Kanokudom, Chompoonut Auphimai, Thanunrat Thongmee, Suvichada Assawakosri, Preeyaporn Vichaiwattana, Ritthideach Yorsaeng, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Pornjarim Nilyanimit, Donchida Srimuan, Thaksaporn Thatsanathorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Yong Poovorawan

Journal: Vaccines (Basel)

PubMed ID: 38400163

Doi: 10.3390/vaccines12020180

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Involvement of a catalase gene in lignin catalysis and immune defense against pathogenic fungus in Coptotermes formosanus: a potential new target for termite control

Authors: Wenhui Zeng, Danni Shen, Wenjing Wu, Shijun Zhang, Zhiqiang Li, Dandan Zhang

Journal: Pest Manag Sci

PubMed ID: 38358092

Doi: 10.1002/ps.8029

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Contribution of to Docosahexaenoic Acid (DHA) Synthesis at the Transcriptional Regulation Level in Common Carp,

Authors: Hanyuan Zhang, Peizhen Li, Youxiu Zhu, Yanliang Jiang, Jianxin Feng, Zixia Zhao, Jian Xu

Journal: Animals (Basel)

PubMed ID: 38396511

Doi: 10.3390/ani14040544

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Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice

Authors: Arezo Kaveh-Samani, Samaneh Dalali, Fatemeh Kaviani, Tohid Piri-Gharaghie, Abbas Doosti

Journal: BMC Immunol

PubMed ID: 38310250

Doi: 10.1186/s12865-024-00602-6

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Comparative analysis of tuberculin and defined antigen skin tests for detection of bovine tuberculosis in buffaloes (Bubalus bubalis) in Haryana state, India

Authors: Mohit Kumar, Tarun Kumar, Babu Lal Jangir, Mahavir Singh, Devan Arora, Yogesh Bangar, Andrew Conlan, Martin Vordermeier, Douwe Bakker, S M Byregowda, Sreenidhi Srinivasan, Vivek Kapur, Naresh Jindal

Journal: BMC Vet Res

PubMed ID: 38395846

Doi: 10.1186/s12917-024-03913-3

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Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation

Authors: Yue Liu, Zhihui Zhang, Hongmiao Hu, Wei Chen, Fan Zhang, Qian Wang, Changshi Wang, Kaige Yan, Jiamu Du

Journal: Nat Plants

PubMed ID: 38413824

Doi: 10.1038/s41477-024-01640-z

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Improving the Efficiency of CRISPR Ribonucleoprotein-Mediated Precise Gene Editing by Small Molecules in Porcine Fibroblasts

Authors: Yunjing Zhao, Xinyu Li, Chang Liu, Chaoqian Jiang, Xiaochen Guo, Qianqian Xu, Zhi Yin, Zhonghua Liu, Yanshuang Mu

Journal: Animals (Basel)

PubMed ID: 38473105

Doi: 10.3390/ani14050719

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