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页码: 35/1072 每页显示数量

In Situ Noninvasive Monitoring of Cell Secretions Based on MOFs/AAO Hybrid Membrane Induced Asymmetric Ion Transport

Authors: Zhaohan Wang , Yafeng Wu , Zhi Wang , Zhaoyan Tian , Yu Liu , Songqin Liu

Journal: Biosensors & bioelectronics

Doi: 10.1016/j.bios.2024.116735

Products & Services: Recombinant Proteins

PICKLE-mediated nucleosome condensing drives H3K27me3 spreading for the inheritance of Polycomb memory during differentiation

Authors: Zhenwei Liang, ∙ Tao Zhu, ∙ Yaoguang Yu,∙ … ∙ Yuhai Cui ∙ Shangzhi Huang ∙ Chenlong Li

Journal: Molecular Cell

Doi: doi.org/10.1016/j.molcel.2024.08.018

Products & Services: Molecular Biology Reagents

Photoexcited Cryptochrome 1 Interacts With SPCHLESS to Regulate Stomatal Development in Arabidopsis

Authors: Li Chen 1 2, Xiaoli Cao , Yupeng Li 1 2, Minqing Liu 1, Yao Liu 1, Yan Guan 1 2, Jiaqi Ruan 1, Zhilei Mao 1 2, Wenxiu Wang 1 2, Hong-Quan Yang 1 2, Tongtong Guo

Journal: PLANT CELL AND ENVIRONMENT

PubMed ID: 39253954

Doi: 10.1111/pce.15123

Products & Services: Antibody Modification and Purification Services

Inhalation of Bioorthogonal Gene-Editable Spiky-Pollen Reprograms Tumor-Associated Macrophages for Lung Cancer Immunotherapy

Authors: Qianglan Lu , Ruiyue Chen , Fei Zeng, Zhiyong Liu, Yongchun Pan, Yanfeng Gao, Bangshun He and Yujun Song

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.202408767

Products & Services: Synthetic Guide RNA

Identification of an RNA-binding perturbing characteristic for thiopurine drugs and their derivatives to disrupt CELF1–RNA interaction

Authors: Yang Tan , Zhibo Zhao , Qingfang Han , Peipei Xu , Xiaopeng Shen , Yajun Jiang , Qiang Xu , Xingxin Wu

Journal: Nucleic Acids Research

PubMed ID: 39268573

Doi: 10.1093/nar/gkae788

Products & Services: Plasmid DNA Preparation

Tuning the fluidity and protein corona of ultrasound-responsive liposomal nanovaccines to program T cell immunity in mice

Authors: Jia He , Chaoyu Wang , Xiao Fang , Junyao Li , Xueying Shen , Junxia Zhang , Cheng Peng , Hongjian Li , Sai Li , Jeffrey M Karp , Rui Kuai

Journal: Nature Communications

PubMed ID: 39284814

Doi: 10.1038/s41467-024-52104-z

Products & Services: Peptide Synthesis

Epitope prime editing shields hematopoietic cells from CD123 immunotherapy for acute myeloid leukemia

Authors: Rui-Jin Ji , Guo-Hua Cao , Wei-Qiang Zhao , Mu-Yao Wang , Pan Gao, Yi-Zhou Zhang, Xue-Bin Wang, Hou-Yuan Qiu , Di-Di Chen, Xiao-Han Tong , Min Duan, Hao Yin, Ying Zhang

Journal: Cell Stem Cell

PubMed ID: 39353428

Doi: 10.1016/j.stem.2024.09.003

Products & Services: Synthetic Guide RNA

Structural characterization of the (deoxy)hypusination in Trichomonas vaginalis questions the bifunctionality of deoxyhypusine synthase

Authors: Elżbieta Wątor, Piotr Wilk, Paweł Kochanowski, Przemysław Grudnik

Journal: FEBS J

Doi: doi.org/10.1111/febs.17207

Products & Services: Gene Synthesis

SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites

Authors: Kaixiang Zhu, Lili Song, Linyue Wang, Lei Hua, Ziyu Luo, Tongyun Wang, Bo Qin, Shuofeng Yuan, Xiaopan Gao, Wenyi Mi, Sheng Cui

Journal: Acta Pharmaceutica Sinica B

PubMed ID: 39309499

Doi: doi.org/10.1016/j.apsb.2024.05.018

Products & Services: Gene Synthesis

Pyroptotic-Spatiotemporally Selective Delivery of siRNA against Pyroptosis and Autoimmune Diseases

Authors: Zongyou Pan, Kaiwang Xu, Guanrui Huang, Haoran Hu, Huang Yang, Haotian Shen, Kaijie Qiu, Canlong Wang, Tengjing Xu, Xinning Yu, Jinhua Fang, Jiajie Wang, Yunting Lin, Jiacheng Dai, Yuting Zhong, Hongyun Song, Sunan Zhu, Siheng Wang, Zhuxing Zhou, Chuyue Sun, Zhaopeng Tang, Shiyao Liao, Guang Yang, Zhiyuan You, Xuesong Dai, Zhengwei Mao

Journal: ADVANCED MATERIALS

PubMed ID: 39081086

Doi: 10.1002/adma.202407115

Products & Services: Recombinant Proteins

Efficient Design of Affilin Protein Binders for HER3

Authors: Anna M. Diaz-Rovira; Jonathan Lotze; Gregor Hoffmann; Chiara Pallara; Alexis Molina; Ina Coburger; Manja Gloser-Br unig; Maren Meysing; Madlen Zwarg; Luc a D az; Victor Guallar; Eva Bosse-Doenecke; Sergi Roda

Journal: International Journal of Molecular Sciences

PubMed ID: 40429825

Doi: 10.3390/ijms26104683

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Efficient Design of Affilin Protein Binders for HER3

Journal: International Journal of Molecular Sciences

PubMed ID: 40429825

Doi: 10.3390/ijms26104683

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Determining the pharmacological potential and biological role of linear pseudoscorpion toxins via functional profiling

Authors: Pelin Erkoc; Susanne Schiffmann; Thomas Ulsh fer; Marina Henke; Michael Marner; Jonas Kr mer; Reinhard Predel; Till F. Sch berle; Sabine Hurka; Ludwig Dersch; Andreas Vilcinskas; Robert F rst; Tim L ddecke

Journal: iScience

PubMed ID: 39021791

Doi: 10.1016/j.isci.2024.110209

Lysophospholipid signaling coordinates outer membrane homeostasis in Escherichia coli

Authors: Gerald R. Enverso; M. Stephen Trent

Journal: MBio

PubMed ID: 41979331

Doi: 10.1128/mbio.00567-26

Products & Services: Gene Synthesis

Pleiotropic Anti-Cancer Activities of Novel Non-Covalent Thioredoxin Reductase Inhibitors Against Triple Negative Breast Cancer

Authors: Brenna Flowers; Abigail Rullo; An Zhang; Keacha Chang; Valentina Z. Petukhova; Sammy Y. Aboagye; Francesco Angelucci; David L. Williams; Steven Kregel; Pavel Petukhov; Irida Kastrati

Journal: Free radical biology & medicine

PubMed ID: 39643141

Doi: 10.1016/j.freeradbiomed.2024.12.010

Mitochondrial rewiring with small-molecule drug-free nanoassemblies unleashes anticancer immunity

Authors: Lulu Ren , Jianqin Wan , Xiaoyan Li , Jie Yao , Yan Ma , Fanchao Meng , Shusen Zheng , Weidong Han , Hangxiang Wang

Journal: Nature Communications

PubMed ID: 39227567

Doi: 10.1038/s41467-024-51945-y

Products & Services: Protein and Antibody Reagents

EXTL3 and NPC1 are mammalian host factors for Autographa californica multiple nucleopolyhedrovirus infection

Authors: Yuege Huang , Hong Mei , Chunchen Deng , Wei Wang , Chao Yuan , Yan Nie , Jia-Da Li , Jia Liu

Journal: Nature Communications

PubMed ID: 39231976

Doi: 10.1038/s41467-024-52193-w

Products & Services: Protein and Antibody Isolation

A bioorthogonal probiotic platform spatiotemporally releases nanobodies in deep tumor for cancer chemoimmunotherapy

Authors: Ruiyue Chen , Qianglan Lu , Fei Zeng , Shurong Qin , Yongchun Pan , Zhiyong Liu , Yuzhen Wang , Bangshun He , Wenjin Qi , Yujun Song

Journal: Materials Today

Doi: 10.1016/j.mattod.2024.09.002

Products & Services: Recombinant Proteins

Rapid generation of long, chemically modified pegRNAs for prime editing

Authors: Xinlin Lei , Anhui Huang , Didi Chen , Xuebin Wang , Ruijin Ji , Jinlin Wang , Yizhou Zhang , Yuming Zhang , Shuhan Lu , Kun Zhang , Qiubing Chen , Ying Zhang , Hao Yin

Journal: Nature Biotechnology

PubMed ID: 39349835

Doi: doi.org/10.1038/s41587-024-02394-x

Products & Services: Custom DNA/RNA Oligos Gene Synthesis Synthetic Guide RNA

Antimony Component Schottky Nanoheterojunctions as UltrasoundHeightened Pyroptosis Initiators for Sonocatalytic Immunotherapy

Authors: Jihu Nie, Nailin Yang , Shumin Sun , Li Wang , Zifan Pei, Jie Wu, Qiao Yu, Zhihui Han ,Youdong Chen , Liang Cheng

Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PubMed ID: 39305135

Doi: 10.1002/anie.202416426

Products & Services: Protein and Antibody Isolation

Pleiotropic Anti-Cancer Activities of Novel Non-Covalent Thioredoxin Reductase Inhibitors Against Triple Negative Breast Cancer

Authors: Brenna Flowers; Abigail Rullo; An Zhang; Keacha Chang; Valentina Z. Petukhova; Sammy Y. Aboagye; Francesco Angelucci; David L. Williams; Steven Kregel; Pavel Petukhov; Irida Kastrati

Journal: Free radical biology & medicine

PubMed ID: 39643141

Doi: 10.1016/j.freeradbiomed.2024.12.010

Design of a Fluorescence Polarization Probe for Enterovirus 2C Proteins

Authors: Kan Li; Hiwot A Demssie; Jun Wang

Journal: Journal of Medicinal Chemistry

PubMed ID: 40542722

Doi: 10.1021/acs.jmedchem.5c01219

Determining the pharmacological potential and biological role of linear pseudoscorpion toxins via functional profiling

Journal: iScience

PubMed ID: 39021791

Doi: 10.1016/j.isci.2024.110209

Determining the pharmacological potential and biological role of linear pseudoscorpion toxins via functional profiling

Journal: iScience

PubMed ID: 39021791

Doi: 10.1016/j.isci.2024.110209

Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening

Authors: Tibor Viktor Szalai; Vincenzo di Lorenzo; Nikolett P czka; Levente M. Mihalovits; L szl Petri; Qirat F. Ashraf; Elvin D. de Araujo; Viktor Honti; D vid Bajusz; Gy rgy M. Keser

Journal: ACS medicinal chemistry letters

PubMed ID: 40529081

Doi: 10.1021/acsmedchemlett.4c00622

Products & Services: Peptide Synthesis

Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening

Authors: Tibor Viktor Szalai; Vincenzo di Lorenzo; Nikolett P czka; Levente M. Mihalovits; L szl Petri; Qirat F. Ashraf; Elvin D. de Araujo; Viktor Honti; D vid Bajusz; Gy rgy M. Keser

Journal: ACS medicinal chemistry letters

PubMed ID: 40529081

Doi: 10.1021/acsmedchemlett.4c00622

Products & Services: Peptide Synthesis

Open-Source Throttling of CD8+ T Cells in Brain with Low-Intensity Focused Ultrasound-Guided Sequential Delivery of CXCL10, IL-2, and aPD-L1 for Glioblastoma Immunotherapy

Authors: Lei Dong , Yini Zhu , Haoge Zhang , Lin Gao , Zhiqi Zhang , Xiaoxuan Xu , Leqian Ying , Lu Zhang , Yue Li , Zhengcheng Yun , Danqi Zhu , Chang Han , Tingting Xu , Hui Yang , Shenghong Ju , Xiaoyuan Chen , Haijun Zhang , Jinbing Xie

Journal: ADVANCED MATERIALS

PubMed ID: 39264011

Doi: 10.1002/adma.202407235

Products & Services: Recombinant Proteins

Strontium-Modified porous attapulgite composite hydrogel scaffold with advanced angiogenic and osteogenic potential for bone defect repair

Authors: Chun Liu , Su Ni , Xiaoyu Wu , Linxiang Zhang , Ting Dai , Aiqin Wang , Hongbin Zhao

Journal: COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING

Doi: doi.org/10.1016/j.compositesa.2024.108492

Products & Services: Protein Electrophoresis and Western

Identification of antimicrobial bioactive peptides from the camel milk protein lactoferrin: Molecular docking, molecular dynamic simulation, and in vitro study

Authors: Mohammed Alzain , Ehab M.M. Ali , Mazin Zamzami , Ishtiaq Qadri , Hani Choudhry , Kamel Chaieb , Bochra Kouidhi , Hisham N. Altayb

Journal: food and humanity

Doi: doi.org/10.1016/j.foohum.2024.100414

Products & Services: Peptide Synthesis

Diffusiophoresis promotes phase separation and transport of biomolecular condensates

Authors: Viet Sang Doan , Ibraheem Alshareedah , Anurag Singh , Priya R Banerjee , Sangwoo Shin

Journal: Nature Communications

PubMed ID: 37461689

Doi: 10.1038/s41467-024-51840-6

Products & Services: Peptide Synthesis

AntigenBoost: enhanced mRNA-based antigen expression through rational amino acid substitution

Authors: Yumiao Gao, Siran Zhu, Huichun Li, Xueting Hao, Wen Chen, Deng Pan, Zhikang Qian

Journal: BRIEFINGS IN BIOINFORMATICS

PubMed ID: 39400114

Doi: 10.1093/bib/bbae468

Products & Services: Gene Synthesis

Efficient Design of Affilin Protein Binders for HER3

Journal: International Journal of Molecular Sciences

PubMed ID: 40429825

Doi: 10.3390/ijms26104683

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Arabidopsis cryptochromes interact with SOG1 to promote the repair of DNA double-strand breaks

Authors: Li Chen , Minqing Liu , Yupeng Li , Yan Guan, Jiaqi Ruan , Zhilei Mao , Wenxiu Wang , Hong-Quan Yang , Tongtong Guo

Journal: BBRC

Doi: 10.1016/j.bbrc.2024.150233

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The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress

Authors: Ying Ma , Jiarong Guo , Haipeng Rao , Jingyu Xin , Xinyi Song , Rui Liu , Shan Shao , Jiajia Hou , Liyu Kong , Zhigang Hu , Lingfeng He , Feiyan Pan , Zhigang Guo

Journal: Journal of extracellular vesicles

PubMed ID: 39235072

Doi: 10.1002/jev2.12505

Products & Services: Gene Synthesis

Chemoproteomic profiling unveils binding and functional diversity of endogenous proteins that interact with endogenous triplex DNA

Authors: Hongzhan Xu , Jing Ye # , Kui-Xing Zhang # , Qingxi Hu , Tongxiao Cui , Chong Tong , Mengqi Wang , Huichao Geng , Kun-Ming Shui , Yan Sun , Jian Wang , Xiaomeng Hou , Kai Zhang , Ran Xie , Yafei Yin , Nan Chen , Jia-Yu Chen

Journal: nature Chemistry

PubMed ID: 39223307

Doi: 10.1038/s41557-024-01609-7

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OsFAD1–OsMYBR22 modulates clustered spikelet through regulating BRD3 in rice

Authors: Mingxing Cheng , Huanran Yuan , Ruihua Wang , Fengfeng Fan , Fengfeng Si , Xiong Luo , Wei Liu , Shaoqing Li

Journal: Journal of integrative plant biology

PubMed ID: 39279451

Doi: doi.org/10.1111/jipb.13775

Products & Services: Peptide Synthesis

Clathrin-associated carriers enable recycling through a kiss-and-run mechanism

Authors: Jiachao Xu, Yu Liang, Nan Li, Song Dang, Amin Jiang, Yiqun Liu, Yuting Guo, Xiaoyu Yang, Yi Yuan, Xinyi Zhang, Yaran Yang, Yongtao Du, Anbing Shi, Xiaoyun Liu, Dong Li, Kangmin He

Journal: Nature Cell Biology

PubMed ID: 39300312

Doi: 10.1038/s41556-024-01499-4

Products & Services: Molecular Biology Reagents

OsGRF6-OsYUCCA1/OsWRKY82 Signaling Cascade Upgrade Grain Yield and Bacterial Blight Resistance in Rice

Authors: Huanran Yuan, Mingxing Cheng, Fengfeng Fan , Xingfei Zheng , Ruihua Wang , Fengfeng Si , Xiong Luo, Nengwu Li 1, Shaoqing Li

Journal: Advanced Science

PubMed ID: 38923395

Doi: 10.1002/advs.202407733

Products & Services: Gene Synthesis

Discovery of alkaline laccases from basidiomycete fungi through machine learning-based approach

Authors: Xing Wan, Sazzad Shahrear, Shea Wen Chew, Francisco Vilaplana, Miia R Mäkelä

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 39261970

Doi: 10.1186/s13068-024-02566-6

Products & Services: Gene Synthesis

Translation of Overlapping Open Reading Frames Promoted by Type 2 IRESs in Avian Calicivirus Genomes

Authors: Yani Arhab , Tatyana V Pestova , Christopher U T Hellen

Journal: Viruses

PubMed ID: 39339889

Doi: 10.3390/v16091413

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Allosteric Covalent Inhibitors of the STAT3 Transcription Factor from Virtual Screening

Authors: Tibor Viktor Szalai; Vincenzo di Lorenzo; Nikolett P czka; Levente M. Mihalovits; L szl Petri; Qirat F. Ashraf; Elvin D. de Araujo; Viktor Honti; D vid Bajusz; Gy rgy M. Keser

Journal: ACS medicinal chemistry letters

PubMed ID: 40529081

Doi: 10.1021/acsmedchemlett.4c00622

Products & Services: Peptide Synthesis

Lysophospholipid signaling coordinates outer membrane homeostasis in Escherichia coli

Authors: Gerald R. Enverso; M. Stephen Trent

Journal: MBio

PubMed ID: 41979331

Doi: 10.1128/mbio.00567-26

Products & Services: Gene Synthesis

Design of a Fluorescence Polarization Probe for Enterovirus 2C Proteins

Authors: Kan Li; Hiwot A Demssie; Jun Wang

Journal: Journal of Medicinal Chemistry

PubMed ID: 40542722

Doi: 10.1021/acs.jmedchem.5c01219

A maternal brain hormone that builds bone

Authors: Muriel E Babey, William C Krause, Kun Chen, Candice B Herber, Zsofia Torok, Joni Nikkanen, Ruben Rodriguez, Xiao Zhang, Fernanda Castro-Navarro, Yuting Wang, Erika E Wheeler, Saul Villeda, J Kent Leach, Nancy E Lane, Erica L Scheller, Charles K F Chan, Thomas H Ambrosi, Holly A Ingraham

Journal: Nature

PubMed ID: 38987585

Products & Services: Peptide Synthesis

Preparation of polyclonal antibody against thrombospondin 2 recombinant protein and its functional verification in pulmonary hypertension syndrome in broilers

Authors: Wen Peng, Chenxi Jiang, Gaofeng Cai, Liling Liu, Xiaoquan Guo, Xiaona Gao, Guyue Li, Zhanhong Zheng, Pei Liu, Ping Liu

Journal: International Journal of Biological Macromolecules

PubMed ID: 38906344

Doi: doi.org/10.1016/j.ijbiomac.2024.133284

Products & Services: Protein and Antibody Isolation

Transcription elongation of the plant RNA polymerase IV is prone to backtracking

Authors: Chengli Fang, Kun Huang, Xiaoxian Wu, Hongwei Zhang, Zhanxi Gu, Jiawei Wang, Yu Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 39178250

Doi: 10.1126/sciadv.adq3087

Products & Services: Protein and Antibody Isolation

A two-pronged nanostrategy of iron metabolism disruption to synergize tumor therapy by triggering the paraptosis-apoptosis hybrid pathway

Authors: Huali Lei , Guanghui Hou , Lin Liu , Zifan Pei , Youdong Chen , Yujie Lu , Nalin Yang , Shumin Sun , Liang Cheng

Journal: ACS Nano

PubMed ID: 39121010

Doi: 10.1021/acsnano.4c06199

Products & Services: Peptide Synthesis

25-Hydroxycholesterol inhibits Hantavirus infection by reprogramming cholesterol metabolism

Authors: Yamei Dang , Yuan Wang , Jing Wei , Hui Zhang , Qiqi Yang , Bin Wang , Jia Li , Chuantao Ye , Yang Chen , Peijun Han , Xiaolei Jin , Jia Wang , Xiaohui Bao , He Liu , Hongwei Ma , Liang Zhang , Linfeng Cheng , Yangchao Dong , Yinlan Bai , Yinghui Li , Yingfeng Lei , Zhikai Xu , Fanglin Zhang , Wei Ye

Journal: FREE RADICAL BIOLOGY AND MEDICINE

PubMed ID: 39209137

Doi: 10.1016/j.freeradbiomed.2024.08.029

Products & Services: Codon Optimization

Activation of ATF3 via the integrated stress response pathway regulates innate immune response to restrict Zika virus

Authors: Pheonah Badu , Gabriele Baniulyte , Morgan A Sammons , Cara T Pager

Journal: Virology Journal

PubMed ID: 39212382

Doi: 10.1128/jvi.01055-24

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Reduced Cross-Protective Potential of Omicron Compared to Ancestral SARS-CoV-2 Spike Vaccines Against Potentially Zoonotic Coronaviruses

Authors: Tyler RennerMatthew StuibleBrian CassSylvie PerretJulie GuimondSimon Lord-DufourMichael J. McCluskieYves DurocherBassel Akache