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A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing

Authors: Yongliang Tong , Runqiu Chen , Xinrong Lu , Cuiying Chen , Guiqin Sun , Xiaolu Yu , Shaoxian Lyu , Meiqing Feng , Yiru Long , Likun Gong , Li Chen

Journal: Int J Biol Macromol

PubMed ID: 39824395

Doi: 10.1016/j.ijbiomac.2025.139953

Products & Services: Gene Synthesis

Restoring tumor antigenicity activates the “bystander” T cell immune cycle

Authors: Yifan Yang , Qiumin Yu , Haoyu Zhang , Yuchen Liu , Hexuan Wang , Ningyi Yang , Yulian Shi , Wanli Zhang , Zijie Wu , Shitong Huang , Wenbin Xie , Ran Duan , Qiuli Mao , Xupeiyao Shi , Zheng Gao , Xiaoning Wang , Hanlin Guo , Lingxiao Chen , Yi Han , Ximing Li , Liyuan Chen , Siqi Tang , Ying Fan , Wenbing Yao , Hong Tian , Xiangdong Gao

Journal: J Control Release

PubMed ID: 39894265

Doi: 10.1016/j.jconrel.2025.01.094

Products & Services: Gene Synthesis

Manganese Galvanic Cells Intervene in Tumor Metabolism to Reinforce cGAS-STING Activation for Bidirectional Synergistic Hydrogen-Immunotherapy

Authors: Nailin Yang , Shumin Sun , Jiachen Xu , Fei Gong, Huali Lei , Yu Hao , Zifan Pei , Chenya Wang , Qiao Yu , Jihu Nie , Nan Jiang , Caifang Ni , Liang Cheng

Journal: Adv Mater

PubMed ID: 10.1002/adma.202414929

Doi: 10.1002/adma.202414929

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Computational design, expression, and characterization of a Plasmodium falciparum multi-epitope, multi-stage vaccine candidate (PfCTMAG)

Authors: Joan A Chick, Nadege N Abongdia, Robert A Shey, Tobias O Apinjoh

Journal: Heliyon

PubMed ID: 39906795

Doi: 10.1016/j.heliyon.2025.e42014

Products & Services: Bacterial Expression

TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy

Authors: Chunyang Cai, Chufeng Gu, Shuai He, Chunren Meng, Dongwei Lai, Jingfa Zhang, Qinghua Qiu

Journal: Clinical epigenetics

PubMed ID: 38172938

Doi: 10.1186/s13148-023-01619-1

Products & Services: Protein and Antibody Isolation

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Authors: Huixia Jia; Lin Yang; Yu Yang; He Liu; Jia Liu; Chunfeng Shang; Zengru Di; Benzhao He; Ke Zhang

Journal: Communications Chemistry

PubMed ID: 41611810

Doi: 10.1038/s42004-026-01914-x

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Authors: Huixia Jia; Lin Yang; Yu Yang; He Liu; Jia Liu; Chunfeng Shang; Zengru Di; Benzhao He; Ke Zhang

Journal: Communications Chemistry

PubMed ID: 41611810

Doi: 10.1038/s42004-026-01914-x

Steric confinement-induced emission probe for monitoring protein conformations in live cells

Authors: Huixia Jia; Lin Yang; Yu Yang; He Liu; Jia Liu; Chunfeng Shang; Zengru Di; Benzhao He; Ke Zhang

Journal: Communications Chemistry

PubMed ID: 41611810

Doi: 10.1038/s42004-026-01914-x

Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer

Authors: Ryan Blawski; Bujamin H. Vokshi; Xinyu Guo; Srushti Kittane; Mirna Sallaku; Wanlu Chen; Martina Gjyzari; Tony Cheung; Yuhan Zhang; Christopher Simpkins; Weiqiang Zhou; Amanda Kulick; Peihua Zhao; Meihan Wei; Pranavkrishna Shivashankar; Tatiana Prioleau; Pedram Razavi; Richard Koche; Vito W. Rebecca; Elisa de Stanchina; Pau Castel; Ho Man Chan; Maurizio Scaltriti; Emiliano Cocco; Hongkai Ji; Minkui Luo; Eneda Toska

Journal: Cell Reports

PubMed ID: 38700982

Doi: 10.1016/j.celrep.2024.114174

Products & Services: Peptide Synthesis

Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome

Authors: Hugh D. Goold, Heinrich Kroukamp, Paige E. Erpf, Yu Zhao, Philip Kelso, Julie Calame, John J. B. Timmins, Elizabeth L. I. Wightman, Kai Peng, Alexander C. Carpenter, Briardo Llorente, Carmen Hawthorne, Samuel Clay, Niël van Wyk, Elizabeth L. Daniel, Fergus Harrison, Felix Meier, Robert D. Willows, Yizhi Cai, Roy S. K. Walker, Xin Xu, Monica I. Espinosa, Giovanni Stracquadanio, Joel S. Bader, …Isak S. Pretorius

Journal: Nature Communications

PubMed ID: 39833175

Doi: 10.1038/s41467-024-55318-3

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Chemical tools to define and manipulate interferon-inducible Ubl protease USP18

Authors: Griffin J. Davis, Anthony O. Omole, Yejin Jung, Wioletta Rut, Ronald Holewinski, Kiall F. Suazo, Hong-Rae Kim, Mo Yang, Thorkell Andresson, Marcin Drag & Euna Yoo

Journal: Nature Communications

PubMed ID: 39843430

Doi: 10.1038/s41467-025-56336-5

Products & Services: Plasmid DNA Preparation

Nuclear Condensates of WW Domain-Containing Adaptor With Coiled-Coil Regulate Mitophagy via Alternative Splicing

Authors: Jiahe Wang, Yi Fan, Guowen Luo, Liang Xiong, Lijie Wang, Zhuoxuan Wu, Jiayi Wang, Zhengying Peng, Clifford J Rosen, Kefeng Lu, Junjun Jing, Quan Yuan, Zhenwei Zhang, Chenchen Zhou

Journal: Advanced Science

PubMed ID: 39840526

Doi: 10.1002/advs.202406759

Products & Services: Protein and Antibody Isolation

Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1

Authors: Fanchong Jian, Jing Wang, Ayijiang Yisimayi, Weiliang Song, Yanli Xu, Xiaosu Chen, Xiao Niu, Sijie Yang, Yuanling Yu, Peng Wang, Haiyan Sun, Lingling Yu, Jing Wang, Yao Wang, Ran An, Wenjing Wang, Miaomiao Ma, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Zhongyang Shen, Ronghua Jin, Yunlong Cao

Journal: Nature

PubMed ID: 39510125

Doi: 10.1038/s41586-024-08315-x

Products & Services: Gene Synthesis Codon Optimization

Spontaneous base flipping helps drive Nsp15’s preferences in double stranded RNA substrates

Authors: Zoe M. Wright, Kevin John Butay, Juno M. Krahn, Isha M. Wilson, Scott A. Gabel, Eugene F. DeRose, Israa S. Hissein, Jason G. Williams, Mario J. Borgnia, Meredith N. Frazier, Geoffrey A. Mueller & Robin E. Stanley

Journal: Nature Communications

PubMed ID: 39755678

Doi: 10.1038/s41467-024-55682-0

Divergent evolution of opposite base specificity and single-stranded DNA activity in animal and plant AP endonucleases

Authors: Marina Jordano-Raya, Carol E Schrader, Rafael R Ariza, Teresa Roldán-Arjona, Dolores Córdoba-Cañero

Journal: Nucleic Acids Research

PubMed ID: 39778867

Doi: 10.1093/nar/gkae1297

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A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD

Authors: Tristan X. McCallister, Colin K. W. Lim, Mayuri Singh, Sijia Zhang, Najah S. Ahsan, William M. Terpstra, Alisha Y. Xiong, M. Alejandra Zeballos C, Jackson E. Powell, Jenny Drnevich, Yifei Kang & Thomas Gaj

Journal: Nature Communications

PubMed ID: 39779681

Doi: 10.1038/s41467-024-55548-5

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Evolution of Omicron lineage towards increased fitness in the upper respiratory tract in the absence of severe lung pathology

Authors: Arthur Wickenhagen, Meaghan Flagg, Julia R. Port, Claude Kwe Yinda, Kerry Goldin, Shane Gallogly, Jonathan E. Schulz, Tessa Lutterman, Brandi N. Williamson, Franziska Kaiser, Reshma K. Mukesh, Sarah van Tol, Brian Smith, Neeltje van Doremalen, Colin A. Russell, Emmie de Wit & Vincent J. Munster

Journal: Nature Communications

PubMed ID: 39799119

Doi: 10.1038/s41467-025-55938-3

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IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer

Authors: Masataka Amisaki, Abderezak Zebboudj, Hiroshi Yano, Siqi Linsey Zhang, George Payne, Adrienne Kaya Chandra, Rebecca Yu, Pablo Guasp, Zachary M. Sethna, Akihiro Ohmoto, Luis A. Rojas, Charlotte Cheng, Theresa Waters, Alexander Solovyov, Stephen Martis, Ashley S. Doane, Charlotte Reiche, Emmanuel M. Bruno, Martina Milighetti, Kevin Soares, Zagaa Odgerel, John Alec Moral, Julia N. Zhao, Mithat Gönen, …Vinod P. Balachandran

Journal: Nature

PubMed ID: 39814891

Doi: 10.1038/s41586-024-08426-5

Products & Services: Recombinant Proteins

Rapid and comprehensive detection of viral antibodies and nucleic acids via an acoustofluidic integrated molecular diagnostics chip: AIMDx

Authors: Jiao Qian , Jianping Xia , Samantha Chiang , Jessica F Liu , Ke Li , Feng Li , Fang Wei , Mohammad Aziz , Yong Kim , Vinson Go , James Morizio , Ruoyu Zhong , Ye He , Kaichun Yang , Otto O Yang , David T W Wong , Luke P Lee , Tony Jun Huang

Journal: SCIENCE ADVANCES

PubMed ID: 39813350

Doi: 10.1126/sciadv.adt5464

Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development

Authors: Han Koo, Kyung Chan Park, Hyun Ahm Sohn, Minho Kang, Dong Joon Kim, Zee-Yong Park, Sehoon Park, Sang Hyun Min, Seong-Hwan Park, Yeon-Mi You, Yohan Han, Bo-Kyung Kim, Chul-Ho Lee, Yeon-Soo Kim, Sang J. Chung, Young Il Yeom & Dong Chul Lee

Journal: Nature Communications

PubMed ID: 39819877

Doi: 10.1038/s41467-024-54476-8

Products & Services: Protein and Antibody Isolation

Single-cell transcriptome atlas of lamprey exploring Natterin- induced white adipose tissue browning

Authors: Yue Pang, Yating Qin, Zeyu Du, Qun Liu, Jin Zhang, Kai Han, Jiali Lu, Zengbao Yuan, Jun Li, Shanshan Pan, Xinrui Dong, Mengyang Xu, Dantong Wang, Shuo Li, Zhen Li, Yadong Chen, Zhisheng Zhao, Zhe Zhang, Shunqin Chuan, Yue Song, Mingjie Sun, Xiaodong Jia, Zhangyong Xia, Liping Zhan, …Guangyi Fan

Journal: Nature Communications

PubMed ID: 39820434

Doi: 10.1038/s41467-025-56153-w

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Lymphatic platelet thrombosis limits bone repair by precluding lymphatic transporting DAMPs

Authors: Yangkang Zheng, Lin Cong, Li Zhao, Pengyu Wang, Lianping Xing, Junling Liu, Hao Xu, Ning Li, Yongjian Zhao, Luying Yuan, Qi Shi, Xueqing Sun, Qianqian Liang & YongJun Wang

Journal: Nature Communications

PubMed ID: 39827193

Doi: 10.1038/s41467-025-56147-8

Products & Services: Protein Electrophoresis and Western

Direct repeat region 3’ end modifications regulate Cas12a activity and expand its applications

Authors: Wei Zhang , Yinyin Zhong , Jiaqi Wang , Guangrong Zou , Qiaozhen Chen , Chaoxing Liu

Journal: Nucleic Acids Res

PubMed ID: 39883010

Doi: 10.1093/nar/gkaf040

Products & Services: PCR Cloning and Subcloning

An Insect Eﬀector Mimics Its Host Immune Regulator to Undermine Plant Immunity

Authors: Jianmei Fu , Shuai Li , Jing Li , Zhichang Zhao , Jing Li , Xinyang Tan , Shan Yu , Maofeng Jing , Keyan Zhu-Salzman , Jichao Fang , Rui Ji

Journal: Adv Sci (Weinh)

PubMed ID: 39853648

Doi: doi.org/10.1002/advs.202409186

Products & Services: Peptide Synthesis

Light signal regulates endoreduplication and tomato fruit expansion through the SlPIF1a-SlTLFP8-SlCDKB2 module

Authors: Jiaojiao Zhang, Jiayi Xu, Xinman Wang, Ying Liu, Shuangtao Li, Jialong Zhang, Lingfeng He, Luqin Guo, Chonghua Li, Xin-Xu Li, Yang-Dong Guo, Na Zhang

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 39847324

Doi: 10.1073/pnas.2404445122

Products & Services: Polyclonal Antibody Services

Deep mutational scanning and machine learning for the analysis of antimicrobial-peptide features driving membrane selectivity

Authors: Justin R. Randall; Luiz C. Vieira; Claus O. Wilke; Bryan W. Davies

Journal: Nature biomedical engineering

PubMed ID: 39085646

Doi: 10.1038/s41551-024-01243-1

Products & Services: Peptide Synthesis

Dictating the spatial-temporal delivery of molecular adjuvant and antigen for the enhanced vaccination

Authors: Yumeng Yan , Xiaonan Huang , Lili Yuan , To Ngai , Guanghui Ma , Yufei Xia

Journal: Biomaterials

PubMed ID: 38968687

Doi: 10.1016/j.biomaterials.2024.122697

Products & Services: Peptide Synthesis

Engineered Magneto-Piezoelectric Nanoparticles-Enhanced Scaffolds Disrupt Biofilms and Activate Oxidative Phosphorylation in Icam1+ Macrophages for Infectious Bone Defect Regeneration

Authors: Hao Wu , Changcheng Chen , Jiangfeng Li , Dongmei Yu , Xun Wu , Hai Huang , Zhen Tang , Qi Wu , Shichao Yan , Ning Wang , Mo Wang , Feilong Wei , Yunlong Yu , Duan Wang , Mengting Shi , Xusong Yue , Pengfei Cao , Zenghui Zheng , Xiaokang Li , Baolin Guo , Lei Shi , Zheng Guo

Journal: ACS Nano

PubMed ID: 39690461

Doi: 10.1021/acsnano.4c13562

Products & Services: Protein Electrophoresis and Western

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Authors: Marcell Crispim; Ignasi Bofill Verdaguer; Agust n Hern ndez; Thales Kronenberger; ngel Fenollar; Lydia Fumiko Yamaguchi; Mar a P a Alberione; Miriam Ramirez; Sandra Souza de Oliveira; Alejandro Miguel Katzin; Luis Izquierdo; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III; Kirk W. Deitsch; James J Collins III

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Remotely Sequential Activation of Biofunctional MXenes for Spatiotemporally Controlled Photothermal Cancer Therapy Integrated with Multimodal Imaging

Authors: Jing Jia , Xiaobo Zhang , Yiran Li , Tian Wang , Ying An , Xinrong Yan , Bin Liu , Chaoyi Yang , Huangxian Ju

Journal: Small

PubMed ID: 39665387

Doi: 10.1002/smll.202410535

Products & Services: Synthetic Guide RNA

High-Speed Sequential DNA Computing Using a Solid-State DNA Origami Register

Authors: Qian Zhang, Mingqiang Li, Yuqing Tang, Jinyan Zhang, Chenyun Sun, Yaya Hao, Jianing Cheng, Xiaodong Xie, Sisi Jia, Hui Lv, Fei Wang, and Chunhai Fan

Journal: ACS central science

Doi: doi.org/10.1021/acscentsci.4c01557

Products & Services: CRISPR KI Templates

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

Authors: Qi Qu, Yan Chen, Yu Wang, Weiche Wang, Shating Long, Heng-Ye Yang, Jianfeng Wu, Mengqi Li, Xiao Tian, Xiaoyan Wei, Yan-Hui Liu, Shengrong Xu, Jinye Xiong, Chunyan Yang, Zhenhua Wu, Xi Huang, Changchuan Xie, Yaying Wu, Zheni Xu, Cixiong Zhang, Baoding Zhang, Jin-Wei Feng, Junjie Chen, Yuanji Feng, Huapan Fang, Liyun Lin, Z K Xie, Beibei Sun, Huayu Tian, Yong Yu, Hai-Long Piao, Xiao-Song Xie, Xianming Deng, Chen-Song Zhang, Sheng-Cai Lin

Journal: Nature

PubMed ID: 39695235

Doi: 10.1038/s41586-024-08348-2

Products & Services: Synthetic Guide RNA

Structural Insights into the High Basal Activity and Inverse Agonism of the Orphan GPR6 Receptor Implicated in Parkinson s Disease

Authors: Mahta Barekatain; Linda C. Johansson; Jordy H. Lam; Hao Chang; Anastasiia V. Sadybekov; Gye Won Han; Joseph Russo; Joshua Bliesath; Nicola Brice; Mark B. L. Carlton; Kumar S. Saikatendu; Hukai Sun; Sean T. Murphy; Holger Monenschein; Hans H. Schiffer; Petr Popov; Corinne A. Lutomski; Carol V. Robinson; Zhi-Jie Liu; Tian Hua; Vsevolod Katritch; Vadim Cherezov

Journal: Science Signaling

PubMed ID: 39626010

Doi: 10.1126/scisignal.ado8741

Structural Insights into the High Basal Activity and Inverse Agonism of the Orphan GPR6 Receptor Implicated in Parkinson s Disease

Journal: Science Signaling

PubMed ID: 39626010

Doi: 10.1126/scisignal.ado8741

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1 N2 loop of Spike N-terminal domain

Authors: Xiao Niu, Zhiqiang Li, Jing Wang, Fanchong Jian, Yuanling Yu, Weiliang Song, Ayijiang Yisimayi, Shuo Du, Zhiying Zhang, Qianran Wang, Ran An, Yao Wang, Peng Wang, Haiyan Sun, Lingling Yu, Sijie Yang, Tianhe Xiao, Qingqing Gu, Fei Shao, Youchun Wang, Junyu Xiao, Yunlong Cao

Journal: Emerg Microbes Infec.

PubMed ID: 39361729

Doi: 10.1080/22221751.2024.2412990

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Exploring bifunctional molecules for anti-SARS-CoV-2 and anti-inflammatory activity through structure-based virtual screening, SAR investigation, and biological evaluation

Authors: Jiani Lu , Yingying He , Yaqi Li , Xixiang Chen , Hongtao Li , Xuwen Chen , Jianrong Xu , Hongzhuan Chen ，Ying Wang , Xiao He , Shunying Liu , Lili Chen

Journal: Int J Biol Macromol

PubMed ID: 39653224

Doi: 10.1016/j.ijbiomac.2024.138529

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Mechanistic study of SCOOPs recognition by MIK2–BAK1 complex reveals the role of N-glycans in plant ligand–receptor– coreceptor complex formation

Authors: Huimin Wu , Lihao Wan , Zunyong Liu , Yunqing Jian , Chenchen Zhang , Xiakun Mao , Zhiyun Wang , Qiang Wang , Yaxin Hu , Lizhong Xiong , Zhujun Xia , Juan Xue , Shan Li , Ping He , Libo Shan , Shutong Xu

Journal: Nat Plants

PubMed ID: 39511418

Doi: 10.1038/s41477-024-01836-3

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Immunoaffinity Intact Top-Down Mass Spectrometry for Quantification of Neuron-Specific Enolase Gamma, a Low-Abundance Protein Biomarker

Authors: Sebastian A H van den Wildenberg , Sylvia A A M Genet , Maarten A C Broeren , Joost L J van Dongen , Maxime C M van den Oetelaar , Luc Brunsveld , Volkher Scharnhorst , Daan van de Kerkhof

Journal: Anal Chem

PubMed ID: 39710932

Doi: 10.1021/acs.analchem.4c04677

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Utilization of Fc-specific peptide to orientally immobilize antibodies markedly improves the analytical performance of lateral flow immunoassay strips for aflatoxin B1

Authors: Jin Li , Xintong Li , Yulian Wang , Qianxu Zhou , Guoqing Shi

Journal: Microchemical Journal

Doi: 10.1016/j.microc.2024.112404

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Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

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Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

Authors: Julia Lara; Lautaro Diacovich; Felipe Trajtenberg; Nicole Larrieux; Emilio L. Malchiodi; Marisa M. Fern ndez; Gabriela Gago; Hugo Gramajo; Alejandro Buschiazzo

Journal: Nature Communications

PubMed ID: 32710080

Doi: 10.1038/s41467-020-17504-x

Products & Services: Recombinant Proteins

Beyond the MEP Pathway: A novel kinase required for prenol utilization by malaria parasites

Journal: PLOS Pathogens

PubMed ID: 38277417

Doi: 10.1371/journal.ppat.1011557

Products & Services: PCR Cloning and Subcloning

Prolonged Omicron-specific B cell maturation alleviates immune imprinting induced by SARS-CoV-2 inactivated vaccine

Authors: Ayijiang Yisimayi, Weiliang Song, Jing Wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Ran An, Yao Wang, Haiyan Sun, Peng Wang, Lingling Yu, Fei Shao, Ronghua Jin, Zhongyang Shen, Youchun Wang, Yunlong Cao

Journal: Emerg Microbes Infec.

PubMed ID: 39360822

Doi: 10.1080/22221751.2024.2412623

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Respiratory syncytial virus glycoprotein G impedes CX3CR1-activation by CX3CL1 and monocyte function

Authors: Robert Meineke, Ayse Agac, Marie-Christin Knittler, Martin Ludlow, Albert D. M. E. Osterhaus & Guus F. Rimmelzwaan

Journal: npj Viruses

Doi: doi.org/10.1038/s44298-024-00075-9

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SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis

Authors: Xiao Guo , Shimin Yang , Zeng Cai , Shunhua Zhu , Hongyun Wang , Qianyun Liu , Zhen Zhang , Jiangpeng Feng , Xianying Chen , Yingjian Li , Jikai Deng , Jiejie Liu , Jiali Li , Xue Tan , Zhiying Fu , Ke Xu , Li Zhou , Yu Chen

Journal: J Cell Biol

PubMed ID: 39680116

Doi: 10.1083/jcb.202404131

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Combinations of HDAC Inhibitor and PPAR Agonist Induce Ferroptosis of Leukemic Stem Cell-like Cells in Acute Myeloid Leukemia

Authors: Hui Zhou, Dongmei Qin, Chendi Xie, Jie Zhou, Shuman Jia, Ziwei Zhou, Yi Qiu, Bing Xu, Jie Zha

Journal: Clinical Cancer Research

PubMed ID: 39321217

Doi: 10.1158/1078-0432.CCR-24-0796.

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An Oral Nanovaccine Secreted by Genetically Engineered and Ultrasound-Responsive Bacteria for Colon Cancer Immunotherapy

Authors: Jiexin Li, Ruiqi Yang, Yihang Yuan, He Ren, Chao Fang, Jonathan F Lovell, and Yumiao Zhang