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Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp

Authors: Maria A Schumacher, Rajiv R Singh, Raul Salinas

Journal: Nucleic Acids Res

PubMed ID: 38832628

Doi: 10.1093/nar/gkae459

Products & Services: Protein and Antibody Isolation

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Authors: Olawale G Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M Lange, Cristian Polo Rivera, Tom D Deegan, Yinchen Chen, Melanie Wightman, Rachel Toth, Karim P M Labib, Sebastian Mathea, Neil Ranson, Rubén Fernández-Busnadiego, Miratul M K Muqit

Journal: SCIENCE ADVANCES

PubMed ID: 38848361

Doi: 10.1126/sciadv.adn7191

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TnpB homologues exapted from transposons are RNA-guided transcription factors

Authors: Tanner Wiegand, Florian T Hoffmann, Matt W G Walker, Stephen Tang, Egill Richard, Hoang C Le, Chance Meers, Samuel H Sternberg

Journal: Nature

PubMed ID: 38926585

Doi: 10.1038/s41586-024-07598-4

Understanding the Phase Behavior of a Multistimuli-Responsive Elastin-like Polymer: Insights from Dynamic Light Scattering Analysis

Authors: Peter C Swanson, Galen P Arnold, Carolyn E Curley, Savannah C Wakita, Jeffery D V Waters, Eva Rose M Balog

Journal: J Phys Chem B

PubMed ID: 38830627

Doi: 10.1021/acs.jpcb.4c00070

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Baculovirus surface display of a chimeric E-NS1 protein of YFV protects against YFV infection

Authors: Carla Tomatis, María Florencia Ferrer, Silvia Aquila, Pablo Daniel Thomas, Paula Nazarena Arrías, Leticia Ferrelli, Matías Pidre, Victor Romanowski, Eugenio Antonio Carrera Silva, Ricardo Martín Gómez

Journal: Vaccine

PubMed ID: 38852036

Doi: 10.1016/j.vaccine.2024.06.013

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Identification and characterization of calcium binding protein, spermatid-associated 1 (CABS1)# in selected human tissues and fluids

Authors: Eduardo Reyes-Serratos, Joy Ramielle L Santos, Lakshmi Puttagunta, Stephen J Lewis, Mechiko Watanabe, Aron Gonshor, Robert Buck, A Dean Befus, Marcelo Marcet-Palacios

Journal: PLoS ONE

PubMed ID: 38753592

Doi: 10.1371/journal.pone.0301855

Development and validation of an HILIC/MS/MS method for determination of nusinersen in rabbit plasma

Authors: Xiao Zhang, Chunjie Sha, Wei Zhang, Fengjuan Zhao, Mingli Zhu, Guangyi Leng, Wanhui Liu

Journal: Heliyon

PubMed ID: 38799737

Doi: 10.1016/j.heliyon.2024.e31213

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Design of antiviral AGO2-dependent short hairpin RNAs

Authors: Yuanyuan Bie, Jieling Zhang, Jiyao Chen, Yumin Zhang, Muhan Huang, Leike Zhang, Xi Zhou, Yang Qiu

Journal: Virol Sin

PubMed ID: 38734183

Doi: 10.1016/j.virs.2024.05.001

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4-Octyl Itaconate Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis Via Regulating Microglia

Authors: Ning Zhao, Ming Yi, Lin-Jie Zhang, Qiu-Xia Zhang, Li Yang

Journal: Inflammation

PubMed ID: 38761250

Doi: 10.1007/s10753-024-02050-1

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Effect of three oral pathogens on the TMA-TMAO metabolic pathway

Authors: Xixuan Wang, Liyuan Chen, Ye Teng, Weige Xie, Lingyan Huang, Juan Wu, Hongwei Wang, Sijing Xie

Journal: Front Cell Infect Microbiol

PubMed ID: 38836053

Doi: 10.3389/fcimb.2024.1413787

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The autophagy protein Atg9 functions in glia and contributes to parkinsonian symptoms in a model of Parkinson's disease

Authors: Shuanglong Yi, Linfang Wang, Margaret S Ho, Shiping Zhang

Journal: Neural Regen Res

PubMed ID: 37862221

Doi: 10.4103/1673-5374.382259

Products & Services: Molecular Biology Reagents

Exosome-derived circUPF2 enhances resistance to targeted therapy by redeploying ferroptosis sensitivity in hepatocellular carcinoma

Authors: Feng-Lin Dong, Zong-Zhen Xu, Ying-Qiao Wang, Tao Li, Xin Wang, Jie Li

Journal: J Nanobiotechnology

PubMed ID: 38811968

Doi: 10.1186/s12951-024-02582-6

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EDA2R knockdown alleviates myocardial ischemia/reperfusion injury through inhibiting the activation of the NF-κB signaling pathway

Authors: Zhi-Hui Guan, Di Yang, Yi Wang, Jia-Bin Ma, Guo-Nian Wang

Journal: Exp Anim

PubMed ID: 38797667

Doi: 10.1538/expanim.24-0020

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Construction and immune effect evaluation of the S protein heptad repeat-based nanoparticle vaccine against porcine epidemic diarrhea virus

Authors: Dan Yang, Xinglin Wang, Xu Yang, Shanshan Qi, Feiyu Zhao, Donghua Guo, Chunqiu Li, Qinghe Zhu, Xiaoxu Xing, Yang Cao, Dongbo Sun

Journal: Virology

PubMed ID: 38801794

Doi: 10.1016/j.virol.2024.110113

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Graph-Based Pangenome of Actinidia chinensis Reveals Structural Variations Mediating Fruit Degreening

Authors: Yingzhen Wang, Pengwei Li, Yanyan Zhu, Feng Zhang, Sijia Zhang, Yan He, Ying Wu, Yunzhi Lin, Hongtao Wang, Wangmei Ren, Lihuan Wang, Ying Yang, Runze Wang, Pengpeng Zheng, Yongsheng Liu, Songhu Wang, Junyang Yue

Journal: Adv Sci (Weinh)

PubMed ID: 38757662

Doi: 10.1002/advs.202400322

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Preamplification-free ultra-fast and ultra-sensitive point-of-care testing via LwaCas13a

Authors: Wanting Zeng, Wanping Chen, Yang Liu, Ting Zhang, Chao Zhai, Wenqiang Li, Longyu Wang, Cheng Zhang, Qili Zeng, Fei Wang, Lixin Ma

Journal: Biosens Bioelectron

PubMed ID: 38776799

Doi: 10.1016/j.bios.2024.116400

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Micro-and nano-plastics induce kidney damage and suppression of innate immune function in zebrafish (Danio rerio) larvae

Authors: Hui Yang, Jian Ju, Yuting Wang, Zhu Zhu, Wenyan Lu, Yingying Zhang

Journal: Sci Total Environ

PubMed ID: 38703841

Doi: 10.1016/j.scitotenv.2024.172952

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Intranasal vaccination with an NDV-vectored SARS-CoV-2 vaccine protects against Delta and Omicron challenges

Authors: Bryce M Warner, Jacob G E Yates, Robert Vendramelli, Thang Truong, Courtney Meilleur, Lily Chan, Alexander Leacy, Phuc H Pham, Yanlong Pei, Leonardo Susta, Sarah K Wootton, Darwyn Kobasa

Journal: npj Vaccines

PubMed ID: 38782986

Doi: 10.1038/s41541-024-00870-8

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Development and characterization of an antibody that recognizes influenza virus N1 neuraminidases

Authors: Nan Chen, Renxi Wang, Wanlu Zhu, Xiangjun Hao, Jing Wang, Guojiang Chen, ChunXia Qiao, Xinying Li, Chenghua Liu, Beifen Shen, Jiannan Feng, Lihui Chai, Zuyin Yu, He Xiao

Journal: PLoS ONE

PubMed ID: 38723016

Doi: 10.1371/journal.pone.0302865

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Design, Construction, and Validation of a Yeast-Displayed Chemically Expanded Antibody Library

Authors: Arlinda Rezhdo, Rebecca L Hershman, James A Van Deventer

Journal: biorxiv

PubMed ID: 38853888

Doi: 10.1101/2024.05.29.596443

Products & Services: Protein and Antibody Isolation

Temperature-dependent iron motion in extremophile rubredoxins - no need for 'corresponding states'

Authors: Francis E Jenney, Hongxin Wang, Simon J George, Jin Xiong, Yisong Guo, Leland B Gee, Juan José Marizcurrena, Susana Castro-Sowinski, Anna Staskiewicz, Yoshitaka Yoda, Michael Y Hu, Kenji Tamasaku, Nobumoto Nagasawa, Lei Li, Hiroaki Matsuura, Tzanko Doukov, Stephen P Cramer

Journal: Sci Rep

PubMed ID: 38806591

Doi: 10.1038/s41598-024-62261-2

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Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2

Authors: Dan Gao, Wei-Wei Yi, Bo Liu, Cong-En Zhang, Cui-Cui Yang, Li Zeng, Lin Li, Guangbin Luo, Lan Zhang, Zhen-Yu Ju, Jia-Bo Wang

Journal: J Adv Res

PubMed ID: 38704089

Doi: 10.1016/j.jare.2024.04.027

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CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma

Authors: Lin Tan, Han Zhang, Yun Ding, Yangyun Huang, Daqiang Sun

Journal: Sci Rep

PubMed ID: 38755183

Doi: 10.1038/s41598-024-61804-x

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Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4

Authors: Jianyao Zeng, Yuan Fang, Zixuan Zhang, Zhenzhen Lv, Xiaodie Wang, Qian Huang, Zhidan Tian, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Jing Yu, Tao Liu, Qijun Qian

Journal: Oncogene

PubMed ID: 38806619

Doi: 10.1038/s41388-024-03066-5

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A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy

Authors: Dan A Tudorica, Bishal Basak, Alexia S Puerta Cordova, Grace Khuu, Kevin Rose, Michael Lazarou, Erika L F Holzbaur, James H Hurley

Journal: J Cell Biol

PubMed ID: 38728007

Doi: 10.1083/jcb.202309015

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Post-transcriptional regulation of the T-box gene midline via the 3'UTR in Drosophila is complex and cell and tissue-dependent

Authors: Kalpana Makhijani, Jordan Mar, Ivana Gaziova, Krishna Moorthi Bhat

Journal: Genetics

PubMed ID: 38805187

Doi: 10.1093/genetics/iyae087

Products & Services: Molecular Biology Reagents

Stacked mutations in wheat homologues of rice SEMI-DWARF1 confer a novel semi-dwarf phenotype

Authors: Barbora Ndreca, Alison Huttly, Sajida Bibi, Carlos Bayon, George Lund, Joshua Ham, Rocío Alarcón-Reverte, John Addy, Danuše Tarkowská, Stephen Pearce, Peter Hedden, Stephen G Thomas, Andrew L Phillips

Journal: BMC Plant Biol

PubMed ID: 38724935

Doi: 10.1186/s12870-024-05098-1

Products & Services: Mutant Libraries

Acts as a Positive Regulator of Secondary Cell Wall Synthesis in Sudan Grass ( S)

Authors: Yanzhong Huang, Juanzi Wu, Jianyu Lin, Zhiwei Liu, Zhengfeng Mao, Chen Qian, Xiaoxian Zhong

Journal: Plants (Basel)

PubMed ID: 38794423

Doi: 10.3390/plants13101352

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Accuracy of Anti-SARS-CoV-2 Antibody in Comparison with Surrogate Viral Neutralization Test in Persons Living with HIV, Systemic Lupus Erythematosus, and Chronic Kidney Disease

Authors: Marita Restie Tiara, Chrisan Bimo Prayuda, Tara Titian Maulidya, Hofiya Djauhari, Dadang Suhendar, Rudi Wisaksana, Laniyati Hamijoyo, Rudi Supriyadi, Agnes Rengga Indrati, Bachti Alisjahbana

Journal: Vaccines (Basel)

PubMed ID: 38793809

Doi: 10.3390/vaccines12050558

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Computer-Aided Semi-Rational Design to Enhance the Activity of l-Sorbosone Dehydrogenase from Gluconobacter oxidans WSH-004

Authors: Dong Li, Xinglong Wang, Lin Huo, Weizhu Zeng, Jianghua Li, Jingwen Zhou

Journal: J Agric Food Chem

PubMed ID: 38701424

Doi: 10.1021/acs.jafc.3c08365

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Engineered probiotics with sustained release of interleukin-2 for the treatment of inflammatory bowel disease after oral delivery

Authors: Maoyi Li, Nanhui Liu, Jiafei Zhu, Yumin Wu, Le Niu, Yi Liu, Linfu Chen, Boxiong Bai, Yu Miao, Yang Yang, Qian Chen

Journal: Biomaterials

PubMed ID: 38735180

Doi: doi.org/10.1016/j.biomaterials.2024.122584

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Cholesterol neutralized vemurafenib treatment by promoting melanoma stem‑like cells via its metabolite 27‑hydroxycholesterol

Authors: Xiaohong Wang, Feiliang Zhong, Tingting Chen, Hongbo Wang, Weifang Wang, Hongkai Jin, Chouyang Li, Xuan Guo, Ying Liu, Yu Zhang, Bo Li

Journal: Cell Mol Life Sci

PubMed ID: 38775844

Doi: 10.1007/s00018-024-05267-3

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Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Authors: Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J Gibbings, Laura Trinkle-Mulcahy, John W Copeland

Journal: Int J Mol Sci

PubMed ID: 38891874

Doi: 10.3390/ijms25115686

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ICG-labeled PD-L1-antagonistic affibody dimer for tumor imaging and enhancement of tumor photothermal-immunotherapy

Authors: Dianlong Jia, Shiqi Zhao, Huimin Liu, Xinyu Zhan, Zhongxia Zhou, Mingjia Lv, Xiufeng Tang, Wen Guo, Hui Li, Lilan Sun, Yidong Zhong, Baoqing Tian, Dandan Yuan, Xiaohui Tang, Qing Fan

Journal: Int J Biol Macromol

PubMed ID: 38704065

Doi: 10.1016/j.ijbiomac.2024.132058

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Ferritinophagy mediates adaptive resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer

Authors: Hui Wang, Qianfan Hu, Yuzhong Chen, Xing Huang, Yipeng Feng, Yuanjian Shi, Rutao Li, Xuewen Yin, Xuming Song, Yingkuan Liang, Te Zhang, Lin Xu, Gaochao Dong, Feng Jiang

Journal: Nat Commun

PubMed ID: 38760351

Doi: 10.1038/s41467-024-48433-8

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HIV-1 with gag processing defects activates cGAS sensing

Authors: Rebecca P Sumner, Henry Blest, Meiyin Lin, Carlos Maluquer de Motes, Greg J Towers

Journal: Retrovirology

PubMed ID: 38778414

Doi: 10.1186/s12977-024-00643-0

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Blue light-mediated gene expression as a promising strategy to reduce antibiotic resistance in Escherichia coli

Authors: Qingwei Jiang, Feng Geng, Juan Shen, Ping Zhu, Zhaoxin Lu, Fengxia Lu, Libang Zhou

Journal: Biotechnol J

PubMed ID: 38719589

Doi: 10.1002/biot.202400023

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Effect of Free Cysteine Residues to Serine Mutation on Cellodextrin Phosphorylase

Authors: Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi

Journal: J Appl Glycosci (1999)

PubMed ID: 38863949

Doi: 10.5458/jag.jag.JAG-2023_0011

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A systematic analysis of affinity tags in the haloarchaeal expression system, for protein purification

Authors: Ram Karan, Dominik Renn, Thorsten Allers, Magnus Rueping

Journal: Front Microbiol

PubMed ID: 38873150

Doi: 10.3389/fmicb.2024.1403623

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CRISPR-Cas9 immune-evasive hESCs are rejected following transplantation into immunocompetent mice

Authors: Henriette Reventlow Frederiksen, Alexandra Glantz, Kåre Kryger Vøls, Søren Skov, Pernille Tveden-Nyborg, Kristine Freude, Ulrik Doehn

Journal: Front Genome Ed

PubMed ID: 38863835

Doi: 10.3389/fgeed.2024.1403395

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Understanding the Enzyme ()-Norcoclaurine Synthase Promiscuity to Aldehydes and Ketones

Authors: Brunno A Salvatti, Marcelo A Chagas, Phillipe O Fernandes, Yan F X Ladeira, Aline S Bozzi, Veronica S Valadares, Ana Paula Valente, Amanda S de Miranda, Willian R Rocha, Vinicius G Maltarollo, Adolfo H Moraes

Journal: J Chem Inf Model

PubMed ID: 38776464

Doi: 10.1021/acs.jcim.3c01773

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Therapeutic potentials of nonpeptidic V2R agonists for partial cNDI-causing V2R mutants

Authors: Ritsuki Kuramoto, Ryoji Kise, Mayu Kanno, Kouki Kawakami, Tatsuya Ikuta, Noriko Makita, Asuka Inoue

Journal: PLoS ONE

PubMed ID: 38748623

Doi: 10.1371/journal.pone.0303507

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HIV BG505 SOSIP664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies

Authors: William O Hahn, K Rachael Parks, Mingchao Shen, Gabriel Ozorowski, Holly Janes, Lamar Ballweber-Fleming, Amanda S Woodward Davis, Chris Duplessis, Mark Tomai, Antu K Dey, Zachary K Sagawa, Stephen C De Rosa, Aaron Seese, Latha Kallur Siddaramaiah, Leonidas Stamatatos, Wen-Hsin Lee, Leigh M Sewall, Dalton Karlinsey, Hannah L Turner, Vanessa Rubin, Sarah Furth, Kellie MacPhee, Michael Duff, Lawrence Corey, Michael C Keefer, Srilatha Edupuganti, Ian Frank, Janine Maenza, Lindsey R Baden, Ollivier Hyrien, Rogier W Sanders, John P Moore, Andrew B Ward, Georgia D Tomaras, David C Montefiori, Nadine Rouphael, M Juliana McElrath

Journal: medrxiv

PubMed ID: 38766048

Doi: 10.1101/2024.05.08.24306957

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A Novel Fluorescence-Based Microplate Assay for High-Throughput Screening of hSULT1As Inhibitors

Authors: Xiaoting Niu, Yufan Fan, Liwei Zou, Guangbo Ge

Journal: Biosensors (Basel)

PubMed ID: 38920579

Doi: 10.3390/bios14060275

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Anticancer Effects of the Trivalent Organoarsenical 2-Amino-4-(dihydroxyarsinoyl) Butanoate

Authors: Venkadesh Sarkarai Nadar, Kunie Yoshinaga-Sakurai, Barry P Rosen

Journal: Organometallics

PubMed ID: 38817537

Doi: 10.1021/acs.organomet.4c00082

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The intrinsic substrate specificity of the human tyrosine kinome

Authors: Tomer M. Yaron-Barir, Brian A. Joughin, Emily M. Huntsman, Alexander Kerelsky, Daniel M. Cizin, Benjamin M. Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M. Orozco, Christina Schoenherr, Cari Sagum, Mark T. Bedford, R. Max Wynn, Shih-Chia Tso, David T. Chuang, Lei Li, Shawn S.-C. Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D. Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C. Frame, Peter V. Hornbeck, Lewis C. Cantley, Benjamin E. Turk, Michael B. Yaffe & Jared L. Johnson

Journal: Nature

PubMed ID: 38720073

Doi: 10.1038/s41586-024-07407-y

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Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin

Authors: Di Qu, Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton, James M. Bean, Inna V. Krieger, James C. Sacchettini, Sabine Ehrt, Courtney C. Aldrich & Dirk Schnappinger

Journal: Nat Commun

PubMed ID: 38755122

Doi: 10.1038/s41467-024-48448-1.

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Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding

Authors: Hongjun Bai, Eric Lewitus, Yifan Li, Paul V. Thomas, Michelle Zemil, Mélanie Merbah, Caroline E. Peterson, Thujitha Thuraisamy, Phyllis A. Rees, Agnes Hajduczki, Vincent Dussupt, Bonnie Slike, Letzibeth Mendez-Rivera, Annika Schmid, Erin Kavusak, Mekhala Rao, Gabriel Smith, Jessica Frey, Alicea Sims, Lindsay Wieczorek, Victoria Polonis, Shelly J. Krebs, Julie A. Ake, Sandhya Vasan, Diane L. Bolton, M. Gordon Joyce, Samantha Townsley & Morgane Rolland

Journal: Nat Commun

PubMed ID: 38724518

Doi: 10.1038/s41467-024-48139-x

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Structural basis for double-stranded RNA recognition by SID1

Authors: Runhao Wang, Ye Cong, Dandan Qian, Chuangye Yan, Deshun Gong

Journal: Nucleic Acids Res

PubMed ID: 38742627

Doi: 10.1093/nar/gkae395

Enhanced detection of ligand-PPARγ binding based on surface plasmon resonance through complexation with SRC1- or NCOR2-related polypeptide

Authors: Yiting Wang , Mingzhu Luo , Luyang Che , Qixin Wu , Jingzhe Li , Yanyan Ma , Jingyi Wang , Changzhen Liu

Journal: International Journal of Biological Macromolecules

PubMed ID: 38670200

Doi: 10.1016/j.ijbiomac.2024.131865

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