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Inhibition of Drp1- Fis1 interaction alleviates aberrant mitochondrial fragmentation and acute kidney injury

Authors: Zhixia Song, Yao Xia, Lang Shi, Hongchu Zha, Jing Huang, Xiaohong Xiang, Huiming Li, Hua Huang, Ruchi Yue, Hongtao Wang, Jiefu Zhu

Journal: Cell Mol Biol Lett

PubMed ID: 38439028

Doi: 10.1186/s11658-024-00553-1

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Comprehensive domain-specific analysis and immunoglobulin G profiling of anti-factor VIII antibodies using a bead-based multiplex immunoassay

Authors: Behnaz Pezeshkpoor, Ann-Cristin Berkemeier, Kerstin Herbst, Thilo Albert, Jens Müller, Johannes Oldenburg

Journal: J Thromb Haemost

PubMed ID: 38453023

Doi: 10.1016/j.jtha.2024.02.016

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CERK1 compromises Fusarium solani resistance by reducing jasmonate level and undergoes a negative feedback regulation via the MMK2-WRKY71 module in apple

Authors: Tingting Pei, Minghui Zhan, Dongshan Niu, Yuerong Liu, Jie Deng, Yuanyuan Jing, Pengmin Li, Changhai Liu, Fengwang Ma

Journal: Plant Cell Environ

PubMed ID: 38515330

Doi: 10.1111/pce.14896

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Superior migration ability of umbilical cord-derived mesenchymal stromal cells (MSCs) toward activated lymphocytes in comparison with those of bone marrow and adipose-derived MSCs

Authors: Akiko Hori, Atsuko Takahashi, Yuta Miharu, Satoru Yamaguchi, Masatoshi Sugita, Takeo Mukai, Fumitaka Nagamura, Tokiko Nagamura-Inoue

Journal: Front Cell Dev Biol

PubMed ID: 38529405

Doi: 10.3389/fcell.2024.1329218

Products & Services: Proteins, Expression, Isolation and Analysis

Enzymatic construction of a library of even- and odd-numbered heparosan oligosaccharides and their N-sulfonated derivatives

Authors: Xintong Xi, Weijiao Zhang, Litao Hu, Ruirui Xu, Yang Wang, Guocheng Du, Jian Chen, Zhen Kang

Journal: Int J Biol Macromol

PubMed ID: 38442831

Doi: 10.1016/j.ijbiomac.2024.130501

Products & Services: Proteins, Expression, Isolation and Analysis

Heterologous expression of taxane genes confers resistance to fall armyworm in Nicotiana benthamiana

Authors: Zhenlu Xu, Yaohua Zhai, Huimin Chang, Da Yan, Pengliang Ge, Guangming Ren, Lijun Zhang, Ye Yuan, Ruoyan Wang, Wentao Li, Fuguang Li, Maozhi Ren, Huijuan Mo

Journal: Plant Cell Rep

PubMed ID: 38472660

Doi: 10.1007/s00299-024-03169-z

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The LPS-inactivating enzyme acyloxyacyl hydrolase protects the brain from experimental stroke

Authors: Yuanbo Zhu, Yue Hu, Zhongwang Liu, Luping Chang, Xue Geng, Xuhui Yin, Bing-Qiao Zhao, Wenying Fan

Journal: Transl Res

PubMed ID: 38522823

Doi: 10.1016/j.trsl.2024.03.007

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Identification and expression analysis of family gene in L

Authors: Jiao Xu, Lingyang Kong, Weichao Ren, Zhen Wang, Lili Tang, Wei Wu, Xiubo Liu, Wei Ma, Shuquan Zhang

Journal: Heliyon

PubMed ID: 38545150

Doi: 10.1016/j.heliyon.2024.e27817

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of the grass carp interleukin-23 receptor and its proinflammatory role in intestinal inflammation

Authors: Panpan Han, Jian Tang, Xufang Xu, Pengkun Meng, Kang Wu, Bingyao Sun, Xuehong Song

Journal: Int J Biol Macromol

PubMed ID: 38521334

Doi: 10.1016/j.ijbiomac.2024.130946

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Correction to "Subtilisin 3 production from Microsporum canis is independent of keratin substrate availability"

Authors:

Journal: J Basic Microbiol

PubMed ID: 38533930

Doi: 10.1002/jobm.202470023

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Taraxasterol enhanced bladder cancer cells radiosensitivity via inhibiting the COX-2/PGE2/JAK2/STAT3/MMP pathway

Authors: Quanxin Wang, Ruiqi Zhang, Yijun He, Guangmin Mao, Zhaolu Kong

Journal: Int J Radiat Biol

PubMed ID: 38442139

Doi: 10.1080/09553002.2024.2324475

Products & Services: DNA Sequencing

Binding and Activation of LRP1-Dependent Cell Signaling in Schwann Cells Using a Peptide Derived from the Hemopexin Domain of MMP-9

Authors: John H Kim, Aashish Shivkumar, Masaki Norimoto, Sascha Castro Lingl, Christian Seitz, Rommie E Amaro, Steve L Gonias, Jerry Yang, Wendy M Campana

Journal: Biochemistry

PubMed ID: 38450612

Doi: 10.1021/acs.biochem.3c00705

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A long-term cohort study: the immune evasion and decreasing neutralization dominated the SARS-CoV-2 breakthrough infection

Authors: Qianyun Liu, Meihua Jin, Fanghua Mei, Hui Fan, Mengxue Gu, Yuzhen Zhang, Shengnan Qian, Xue Tan, Lei Ji, Zhen Zhang, Guozhong Chen, Huan Yan, Yu Chen, Ke Lan, Qing Geng, Kun Cai, Li Zhou

Journal: Front Cell Infect Microbiol

PubMed ID: 38572316

Doi: 10.3389/fcimb.2024.1381877

Products & Services: Proteins, Expression, Isolation and Analysis

Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability

Authors: Minhui Ye, Yingzhe Fang, Lu Chen, Zemin Song, Qing Bao, Fei Wang, Hao Huang, Jin Xu, Ziwen Wang, Ruijing Xiao, Meng Han, Song Gao, Hudan Liu, Baishan Jiang, Guoliang Qing

Journal: Nat Commun

PubMed ID: 38493213

Doi: 10.1038/s41467-024-46572-6

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Reduction in Interferon-Stimulated Genes Contributes to High-Yield Production of Influenza Virus in Suspension MDCK Cells

Authors: Qi Wang, Jian Luo, Beibei Li, Qian Ye, Wenting Xu, Feixia Gao, Linting Zhou, Wenyue Lu, Wen-Song Tan, Xiuling Li

Journal: Vaccines

PubMed ID: 38543921

Doi: 10.3390/vaccines12030287

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular basis for substrate transport of Mycobacterium tuberculosis ABC importer DppABCD

Authors: Tianyu Hu, Xiaolin Yang, Yuanchen Zhu, Fengjiang Liu, Xiuna Yang, Zhiqi Xiong, Jingxi Liang, Zhenli Lin, Yuting Ran, Luke W Guddat, Zihe Rao, Bing Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38507491

Doi: 10.1126/sciadv.adk8521

Products & Services: Proteins, Expression, Isolation and Analysis

The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation

Authors: Hang Xu, Zihao Yuan, Kunpeng Qin, Shuai Jiang , Li Sun

Journal: Elife

PubMed ID: 38489483

Doi: 10.7554/eLife.89974

Products & Services: Proteins, Expression, Isolation and Analysis

Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1

Authors: Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Gengfu Xiao, Zihe Rao, Lu Lu, Leike Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu

Journal: Signal Transduct Target Ther

PubMed ID: 38443334

Doi: 10.1038/s41392-024-01758-8

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Design and synthesis of APN and 3CLpro dual-target inhibitors based on STSBPT with anticoronavirus activity

Authors: Youle Zheng, Jin Feng, Yanbin Song, Yixin Yu, Min Ling, Mengjia Zhang, Haijiao Xie, Wentao Li

Journal: J Med Virol

PubMed ID: 38483056

Doi: 10.1002/jmv.29512

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Effects of annexin B18 from Echinococcus granulosus sensu lato on mouse macrophages

Authors: Yanxin Chen, Ruiqi Hua, Guoqing Shao, Xiaowei Zhu, Wei Hou, Shengqiong Li, Aiguo Yang, Guangyou Yang

Journal: Exp Parasitol

PubMed ID: 38432406

Doi: 10.1016/j.exppara.2024.108723

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Transmission Reducing and Enhancing Monoclonal Antibodies against Plasmodium vivax Gamete Surface Protein Pvs48/45

Authors: Geetha P Bansal, Maisa da Silva Araujo, Yi Cao, Emily Shaffer, Jessica Evangelista Araujo, Jansen Fernandes Medeiros, Clifford Hayashi, Joseph Vinetz, Nirbhay Kumar

Journal: Infect Immun

PubMed ID: 38289124

Doi: 10.1128/iai.00374-23

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Structure of the human KMN complex and implications for regulation of its assembly

Authors: Soumitra Polley, Tobias Raisch, Sabrina Ghetti, Marie Körner, Melina Terbeck, Frauke Gräter, Stefan Raunser, Camilo Aponte-Santamaría, Ingrid R Vetter, Andrea Musacchio

Journal: NATURE STRUCTURAL & MOLECULAR BIOLOGY

PubMed ID: 38459128

Doi: 10.1038/s41594-024-01230-9

Products & Services: Peptide Synthesis

Design of amyloidogenic peptide traps

Authors: Danny D Sahtoe, Ewa A Andrzejewska, Hannah L Han, Enrico Rennella, Matthias M Schneider, Georg Meisl, Maggie Ahlrichs, Justin Decarreau, Hannah Nguyen, Alex Kang, Paul Levine, Mila Lamb, Xinting Li, Asim K Bera, Lewis E Kay, Tuomas P J Knowles, David Baker

Journal: Nature Chemical Biology

PubMed ID: 38503834

Doi: 10.1038/s41589-024-01578-5

Products & Services: Gene Synthesis

Efficient production of isomaltulose using engineered Yarrowia lipolytica strain facilitated by non-yeast signal peptide-mediated cell surface display

Authors: Juanjuan Liu, Jiao Li, Peng Chen, Yan Zeng, Jiangang Yang, Yuanxia Sun

Journal: J Sci Food Agric

PubMed ID: 38436580

Doi: 10.1002/jsfa.13426

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miR396b/GRF6 module contributes to salt tolerance in rice

Authors: Huanran Yuan, Mingxing Cheng, Ruihua Wang, Zhikai Wang, Fengfeng Fan, Wei Wang, Fengfeng Si, Feng Gao, Shaoqing Li

Journal: Plant Biotechnol J

PubMed ID: 38454780

Doi: 10.1111/pbi.14326

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De Novo Multienzyme Synthetic Pathways for Lactic Acid Production

Authors: Xu-Wei Ding, Jing Rong, Ze-Peng Pan, Xin-Xin Zhu, Zhen-Yu Zhu, Qi Chen, Zhi-Jun Zhang, Jian-He Xu, Chun-Xiu Li, and Gao-Wei Zheng

Journal: ACS Catal

Doi: doi.org/10.1021/acscatal.3c05489

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lncCPSET1 acts as a scaffold for MLL2/COMPASS to regulate Bmp4 and promote the formation of chicken primordial germ cells

Authors: Ying Ding, Chen Zhang, Qisheng Zuo, Kai Jin, Bichun Li

Journal: Mol Genet Genomics

PubMed ID: 38551742

Doi: 10.1007/s00438-024-02127-4

Products & Services: Molecular Biology Reagents

Adaptive Darwinian off-target resistance mechanisms to selective RET inhibition in RET driven cancer

Authors: Vivek Subbiah, Mohamed A Gouda, J Bryan Iorgulescu, Ramona Dadu, Keyur Patel, Steven Sherman, Maria Cabanillas, Mimi Hu, Luz E Castellanos, Behrang Amini, Funda Meric-Bernstam, Tao Shen, Jie Wu

Journal: NPJ Precis Oncol

PubMed ID: 38438731

Doi: 10.1038/s41698-024-00563-4

Products & Services: Molecular Biology Reagents

Evaluating microcystinase A-based approach on microcystins degradation during harvested cyanobacterial blooms

Authors: Siyu Yang, Jun Zuo, Hans-Peter Grossart, Guofei Dai, Jin Liu, Lirong Song, Nanqin Gan

Journal: Environ Pollut

PubMed ID: 38548158

Doi: 10.1016/j.envpol.2024.123878

Products & Services: Molecular Biology Reagents

Microfluidic Synthesis of Scalable Layer-by-Layer Multiple Antigen Nano-Delivery Platform for SARS-CoV-2 Vaccines

Authors: Yang Xu, Kazuya Masuda, Christine Groso, Rick Hassan, Ziyou Zhou, Kelsey Broderick, Moriya Tsuji, Christopher Tison

Journal: Vaccines (Basel)

PubMed ID: 38543973

Doi: 10.3390/vaccines12030339

Products & Services: Proteins, Expression, Isolation and Analysis

Nanopore analysis of salvianolic acids in herbal medicines

Authors: Pingping Fan, Shanyu Zhang, Yuqin Wang, Tian Li, Hanhan Zhang, Panke Zhang, Shuo Huang

Journal: Nat Commun

PubMed ID: 38443335

Doi: 10.1038/s41467-024-45543-1

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Characterization of c-di-AMP signaling in the periodontal pathobiont, Treponema denticola

Authors: Aidan D Moylan, Dhara T Patel, Claire O'Brien, Edward J A Schuler, Annie N Hinson, Richard T Marconi, Daniel P Miller

Journal: Mol Oral Microbiol

PubMed ID: 38436552

Doi: 10.1111/omi.12458

Products & Services: Proteins, Expression, Isolation and Analysis

Safety and immunogenicity of CoronaVac and ChAdOx1 heterologous prime-boost vaccines in an overweight population in Chiang Mai, Thailand

Authors: Kriangkrai Chawansuntati, Supachai Sakkhachornphop, Sayamon Hongjaisee, Saranta Freeouf, Patumrat Sripan, Nattaya Nusartsang, Romanee Chaiwarith, Tavitiya Sudjaritruk, Khuanchai Supparatpinyo, Jiraprapa Wipasa

Journal: Vaccine X

PubMed ID: 38549951

Doi: 10.1016/j.jvacx.2024.100475

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Machine learning developed a CD8 exhausted T cells signature for predicting prognosis, immune infiltration and drug sensitivity in ovarian cancer

Authors: Rujun Chen, Yicai Zheng, Chen Fei, Jun Ye, He Fei

Journal: Sci Rep

PubMed ID: 38461331

Doi: 10.1038/s41598-024-55919-4

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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy

Authors: Gerhard Frey, Ana Paula G Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler, Hwai Wen Chang, William J Boyle, Jay M Short

Journal: MAbs

PubMed ID: 38445633

Doi: 10.1080/19420862.2024.2322562

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Mt10 Vaccine Protects Diversity Outbred Mice from CVB3 Infection by Producing Virus-Specific Neutralizing Antibodies and Diverse Antibody Isotypes

Authors: Mahima T Rasquinha, Kiruthiga Mone, Meghna Sur, Ninaad Lasrado, Chandirasegaran Massilamany, Stephen D Kachman, David Steffen, Jay Reddy

Journal: Vaccines (Basel)

PubMed ID: 38543901

Doi: 10.3390/vaccines12030266

Products & Services: Proteins, Expression, Isolation and Analysis

ENGINEERED NANOBODIES WITH PROGRAMMABLE TARGET ANTIGEN PROTEOLYSIS (PTAP) FUSIONS REGULATE INTRACELLULAR ALPHA-SYNUCLEIN IN VITRO AND IN VIVO

Authors: Diptaman Chatterjee, Lianna Y D'Brant, Benjamin M Hiller, David J Marmion, Ivette M Sandoval, Kelvin C Luk, Fredric P Manfredsson, Anne Messer, Jeffrey H Kordower, David C Butler

Journal: Res Sq

PubMed ID: 38585932

Doi: 10.21203/rs.3.rs-4088206/v1

Products & Services: Proteins, Expression, Isolation and Analysis

ADAMTS5 Promotes Permeability of the Blood-Brain Barrier during Subspecies Invading the Central Nervous System

Authors: Zuoxi Chen, Fangzhi Du, Ruihua Zhang, Qingyun Wu, Zhiyu Lu, Rui-Li Zhang, Qianqiu Wang

Journal: ACS Infect Dis

PubMed ID: 38536197

Doi: 10.1021/acsinfecdis.3c00664

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A network pharmacological approach for the identification of potential therapeutic targets of - a complex traditional Siddha formulation

Authors: Agnes Preethy H, Yanamandram Balasubramanian Venkatakrishnan, Vigneshwar Ramakrishnan, Uma Maheswari Krishnan

Journal: J Biomol Struct Dyn

PubMed ID: 38459935

Doi: 10.1080/07391102.2024.2322612

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The eukaryotic-like characteristics of small GTPase, roadblock and TRAPPC3 proteins from Asgard archaea

Authors: Linh T Tran, Caner Akıl, Yosuke Senju, Robert C Robinson

Journal: Commun Biol

PubMed ID: 38472392

Doi: 10.1038/s42003-024-05888-1

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Expression and functional analysis of a recombinant aquaporin Z from Antarctic Pseudomonas sp AMS3

Authors: S Balakrishnan, R N Z R A Rahman, N D M Noor, W Latip, M S M Ali

Journal: Proteins

PubMed ID: 38477414

Doi: 10.1002/prot.26680

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Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin

Authors: Ruoyu Zhou, Liuqing He, Jiahao Zhang, Xiaofeng Zhang, Yanyan Li, Xiechao Zhan, Liang Tao

Journal: Nat Commun

PubMed ID: 38438396

Doi: 10.1038/s41467-024-46394-6

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Is there an immunological cross-reactivity of antibodies to the myelin oligodendrocyte glycoprotein and coronaviruses?

Authors: Kathrin Schanda, Sara Mariotto, Dagmar Rudzki, Angelika Bauer, Alessandro Dinoto, Patrizia Rossi, Sergio Ferrari, Sven Jarius, Brigitte Wildemann, Federica Boso, Bruno Giometto, Daniel Engels, Tania Kümpfel, Eva-Maria Wendel, Kevin Rostasy, Markus Reindl

Journal: Brain Commun

PubMed ID: 38576796

Doi: 10.1093/braincomms/fcae106

Products & Services: Proteins, Expression, Isolation and Analysis

Gene regulatory network co-option is sufficient to induce a morphological novelty in

Authors: Gavin Rice, Tatiana Gaitan-Escudero, Kenechukwu Charles-Obi, Julia Zeitlinger, Mark Rebeiz

Journal: biorxiv

PubMed ID: 38585823

Doi: 10.1101/2024.03.22.584840

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Evaluation of Long-Term Adaptive Immune Responses Specific to SARS-CoV-2: Effect of Various Vaccination and Omicron Exposure

Authors: Hyunhye Kang, Jin Jung, Geon Young Ko, Jihyun Lee, Eun-Jee Oh