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Targeting Antigen-Presenting Cells to Enhance the Tumor-Spleen Immunity Cycle through Liposome-Neoantigen Vaccine

Authors: Yu Xu, Bing Wang, Yue Huang, JianPing Liao, Chenyi Wu, Chenxi Zhou, Zishi Kang, Shiyang Jiang, Bing-Chen Wu, Da Zhang, Ruihua Xu, Xiaolong Liu, Feng Wang

Journal: Advanced Science

PubMed ID: 40125791

Doi: 10.1002/advs.202500021

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Nanoscale DNA tracing reveals the self-organization mechanism of mitotic chromosomes

Authors: Kai Sandvold Beckwith, Andreas Brunner, Natalia Rosalia Morero, Ralf Jungmann, Jan Ellenberg

Journal: Cell

PubMed ID: 39554202

Doi: 10.1101/2024.10.28.620625

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A humanised ACE2, TMPRSS2, and FCGRT mouse model reveals the protective efficacy of anti-receptor binding domain antibodies elicited by SARS-CoV-2 hybrid immunity

Authors: Fernanda Ana-Sosa-Batiz; Shailendra Kumar Verma; Norazizah Shafee; Robyn Miller; Chris Conner; Kathryn M. Hastie; Julia Timis; Erin Maule; Michael N. Nguyen; Linda Tran; Krithik Varghese; Henry Madany; Audrey Elizabeth Street; Michelle Zandonatti; Meng Ling Moi; Kurt Jarnagin; David R. Webb; Erica Ollmann Saphire; Kenneth Kim; Sujan Shresta

Journal: EBioMedicine

PubMed ID: 40020261

Doi: 10.1016/j.ebiom.2025.105619

Products & Services: Protein and Antibody Isolation

Astragalus Polysaccharides Ameliorate Diabetic Bladder Dysfunction via Normalization of Neuromuscular Conduction

Authors: Shaochan Liang, Siyuan Xu, Shenglian Ye, Lang Liang, Hongliang Li, Jiaye Liu, Yao Zhang, Feng Zou, Xiaodan Liang, Bo Tan, Hongying Cao

Journal: J Agric Food Chem

PubMed ID: 40032633

Doi: 10.1021/acs.jafc.4c11577

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The structure and function of the ghrelin receptor coding for drug actions

Authors: Yuki Shiimura, Dohyun Im, Ryosuke Tany, Hidetsugu Asada, Ryoji Kise, Eon Kurumiya, Hideko Wakasugi-Masuho, Satoshi Yasuda, Kazuma Matsui, Jun-Ichi Kishikawa, Takayuki Kato, Takeshi Murata, Masayasu Kojima, So Iwata, Ikuo Masuho

Journal: Nat Struct Mol Biol

PubMed ID: 39833471

Doi: 39833471

Products & Services: Gene Synthesis

Expediting Genome Synthesis of Corynebacterium glutamicum with An Artificial Chromosome Vector

Authors: Zhanhua Zhang, Peixiong Hong, Zebin Li, Baitao Li, Tai Chen, Yue Shen, Xiaofeng Yang, Yanrui Ye, Yun Wang, Zhanglin Lin

Journal: Trends Biotechnol

PubMed ID: 40155267

Doi: 10.1016/j.tibtech.2025.02.019

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The E3 ubiquitin ligase SlATL2 suppresses tomato immunity by promoting SlCSN5a degradation during Pseudomonas syringae pv. tomato DC3000 infection

Authors: Yujie Dai, Xiaodan Li, Yeling He, Liya Zhu, Yan Bi, Fengming Song, Dayong Li

Journal: Horticulture research

PubMed ID: 40303438

Doi: 10.1093/hr/uhaf078

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The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade

Authors: Yijian Qiu; Olivia T. Stamatatos; Qingting Hu; Jed de Ruiter Swain; Suzanne Russo; Ava Sann; Ana S. H. Costa; Sara Violante; David L. Spector; Justin R. Cross; Michael J. Lukey

Journal: Nature metabolism

PubMed ID: 39192144

Doi: 10.1038/s42255-024-01104-w

Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator

Authors: Demeng Sun, Xiang Li, Qingning Yuan, Yuanxia Wang, Pan Shi, Huanhuan Zhang, Tao Wang, Wenjing Sun, Shenglong Ling, Yuanchun Liu, Jinglin Lai, Wenqin Xie, Wanchao Yin, Lei Liu, H. Eric Xu, Changlin Tian

Journal: Cell Res

PubMed ID: 40118988

Doi: doi.org/10.1038/s41422-025-01095-7

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A Functional 3D Biomimetic Osteon Accelerates Bone Regeneration

Authors: Chenxu Zhu, Zexi Li, Xubin Qiu, Baizhen Zhao, Huan Wang, Lijie Wang, Ming Zhuang, Jinbo Liu, Fengxuan Han, Bin Li

Journal: Advanced Functional Materials

Doi: 10.1002/adfm.202500603

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Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide–HLA-I Fusion Protein by Armoring with Mutein IFNα

Authors: Douwe Freerk Samplonius , Anne Paulien van Wijngaarden , Lisanne Koll , Xiurong Ke , Wijnand Helfrich

Journal: Int J Mol Sci

PubMed ID: 40243928

Doi: ijms26073178

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Antigen-presenting cancer associated fibroblasts enhance antitumor immunity and predict immunotherapy response

Authors: Junquan Song, Rongyuan Wei, Chenchen Liu, Zhenxiong Zhao, Xuanjun Liu, Yanong Wang, Fenglin Liu, Xiaowen Liu

Journal: Nature Communications

PubMed ID: 40038297

Doi: 10.1038/s41467-025-57465-7

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Structural basis for the activation of plant bunyavirus replication machinery and its dual-targeted inhibition by ribavirin

Authors: Jia Li, Lei Cao, Yaqian Zhao, Jinghan Shen, Lei Wang, Mingfeng Feng, Min Zhu, Yonghao Ye, Richard Kormelink, Xiaorong Tao, Xiangxi Wang

Journal: Nat Plants

PubMed ID: 40044941

Doi: 10.1038/s41477-025-01940-y

Oxytocin induces embryonic diapause

Authors: Jessica L Minder, Sarah B Winokur, Janaye Stephens, Jie Tong, Naomi L Cassel, Luisa Schuster, Habon A Issa, Michael Cammer, Latika Khatri, Gaia Moisan, Maria Alvarado-Torres, Orlando Aristizábal, Youssef Z Wadghiri, Sang Yong Kim, Silvana Valtcheva, Catherine Pei-Ju Lu, Moses V Chao, Robert C Froemke

Journal: SCIENCE ADVANCES

PubMed ID: 40043121

Doi: 10.1126/sciadv.adt1763

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Monitoring mRNA vaccine antigen expression in vivo using PET/CT

Authors: Gabrielle S Blizard, Garima Dwivedi, Yi-Gen Pan, Catherine Hou, Jean M Etersque, Hooda Said, Anik Chevrier, Marc Lavertu, Houping Ni, Benjamin Davis, Ying Tam, Quy Cao, Robert H Mach, Drew Weissman, Mohamad-Gabriel Alameh, Mark A Sellmyer

Journal: Nature Communications

PubMed ID: 40044669

Doi: 10.1038/s41467-025-57446-w

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The conductance of KCNQ2 and its pathogenic variants is determined by individual subunit gating

Authors: Andy Hinojo-Perez, Jodene Eldstrom, Ying Dou, Allan Marinho-Alcara, Michaela A Edmond, Alicia de la Cruz, Marta E Perez Rodriguez, Maykelis Diaz-Solares, Derek M Dykxhoorn, David Fedida, Rene Barro-Soria

Journal: SCIENCE ADVANCES

PubMed ID: 40043113

Doi: 10.1126/sciadv.adr7012

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Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

Authors: Lanfang Ren, Zeda Zhao, Yuqing Chao, Panting Yu, Zhoufang Mei, Bing Du, Yiyun Cheng

Journal: Advanced Science

PubMed ID: 40056044

Doi: 10.1002/advs.202500844

The structural basis for the human procollagen lysine hydroxylation and dual-glycosylation

Authors: Junjiang Peng, Wenguo Li, Deqiang Yao, Ying Xia, Qian Wang, Yan Cai, Shaobai Li, Mi Cao, Yafeng Shen, Peixiang Ma, Rijing Liao, Jie Zhao, An Qin, Yu Cao

Journal: Nature Communications

PubMed ID: 40069201

Doi: 10.1038/s41467-025-57768-9

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USP7 V517F mutation as a mechanism of inhibitor resistance

Authors: Yu-Ling Miao, Fengying Fan, Yong-Jun Cheng, Li Jia, Shan-Shan Song, Xia-Juan Huan, Xu-Bin Bao, Jian Ding, Xuekui Yu, Jin-Xue He

Journal: Nature Communications

PubMed ID: 40087304

Doi: 10.1038/s41467-025-56981-w

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Authors: Jingjing Wang, Yong Ma, Zimu Li, Hang Yuan, Banghui Liu, Zexuan Li, Mengzhen Su, Gul Habib, Yutong Liu, Lutang Fu, Peiyi Wang, Mei Li, Jun He, Jing Chen, Peng Zhou, Zhengli Shi, Xinwen Chen, Xiaoli Xiong

Journal: SCIENCE ADVANCES

PubMed ID: 40085715

Doi: 10.1126/sciadv.adr8772

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Developing Quorum Sensing-Based Collaborative Dynamic Control System in Halomonas TD01

Authors: Yi-Na Lin, Yu-Xi Li, Ye Zheng, Yi-Hao Deng, Kai-Xuan Liu, Yue Gan, Hao Li, Jun Wang, Jia-Wen Peng, Rui-Zhe Deng, Huai-Ming Wang, Hui Wang, Jian-Wen Ye

Journal: Advanced Science

PubMed ID: 40091435

Doi: 10.1002/advs.202408083

Products & Services: Protein Electrophoresis and Western

Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma

Authors: Hao Shi, Yajie Yang, Jiwei Gao, Satendra Kumar, Hong Xie, Ziqing Chen, Jiawen Lyu, Harri Sihto, Virve Koljonen, Silvia Vega-Rubin-de-Celis, Vladana Vukojevic, Filip Farnebo, Viveca Björnhagen, Anders Höög, C Christofer Juhlin, Linkiat Lee, Malin Wickström, Jürgen C Becker, John Inge Johnsen, Catharina Larsson, Weng-Onn Lui

Journal: Nature Communications

PubMed ID: 40108758

Doi: 10.1080/15548627.2025.2477385

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Acute diacylglycerol production activates critical membrane-shaping proteins leading to mitochondrial tubulation and fission

Authors: Joshua G Pemberton, Krishnendu Roy, Yeun Ju Kim, Tara D Fischer, Vijay Joshi, Elizabeth Ferrer, Richard J Youle, Thomas J Pucadyil, Tamas Balla

Journal: Nature Communications

PubMed ID: 40102394

Doi: 10.1038/s41467-025-57439-9

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Reprogramming yeast metabolism for customized starch-rich micro-grain through low-carbon microbial manufacturing

Authors: Zhihui Shi, Zhaoyu Xu, Weihe Rong, Hongbing Sun, Hongyi Zhou, Qianqian Yuan, Aixuan Xiao, Hongfei Ma, Tao Cai, Guokun Wang, Yanhe Ma

Journal: Nature Communications

PubMed ID: 40118900

Doi: 10.1038/s41467-025-58067-z

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Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome

Authors: Jessica C Hargarten, Kenneth Ssebambulidde, Seher H Anjum, Malcolm J Vaughan, Jintao Xu, Anutosh Ganguly, Brittany Dulek, Francisco Otaizo-Carrasquero, Brian Song, Sijia Tao, Yoon-Dong Park, Terri L Scott, Tracey-Ann Höltermann, Raymond F Schinazi, Prashant Chittiboina, Bridgette Jeanne Billioux, Dima A Hammoud, Michal A Olszewski, Peter R Williamson

Journal: SCIENCE ADVANCES

PubMed ID: 40117367

Doi: 10.1126/sciadv.adi9885

Products & Services: Protein Electrophoresis and Western

Large Library Docking for Polypharmacology

Authors: Yujin Wu; Seth Vigneron; Joao Braz; Karthik Srinivasan; Elissa A. Fink; Xi-Ping Huang; Xinyu Xu; Harald Huebner; Joseph Y. Kim; Jing Wang; Tara Pfeiffer; Kensuke Sakamoto; Dmytro S. Radchenko; Ramona M. Rodriguiz; Yurii S. Moroz; John J. Irwin; Peter Gmeiner; Christian Billesboelle; Bryan L. Roth; Allan I. Basbaum; Aashish Manglik; William C. Wetsel; Brian K. Shoichet

Journal: Journal of Medicinal Chemistry

PubMed ID: 41712624

Doi: 10.1021/acs.jmedchem.5c03810

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GLP1 alleviates oleic acid-propelled lipocalin-2 generation by tumor-infiltrating CD8+ T cells to reduce polymorphonuclear MDSC recruitment and enhances viral immunotherapy in pancreatic cancer

Authors: Jingyi Wu, Peng Qian, Yifeng Han, Chuning Xu, Mao Xia, Ping Zhan, Jiwu Wei, Jie Dong

Journal: Cellular & molecular immunology

PubMed ID: 39910336

Doi: 10.1038/s41423-025-01260-3

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Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery

Authors: Jiaolong Wang, Rune T Kidmose, Niels Boegholm, Nevin K Zacharia, Mads B Thomsen, Anni Christensen, Tara Malik, Karl Lechtreck, Esben Lorentzen

Journal: The Journal of Biological Chemistry

PubMed ID: 39880089

Doi: 10.1016/j.jbc.2025.108237

Products & Services: Gene Synthesis Codon Optimization

Cell-autonomous innate immunity by proteasome-derived defence peptides

Authors: Karin Goldberg, Arseniy Lobov, Paola Antonello, Merav D Shmueli, Idan Yakir, Tal Weizman, Adi Ulman, Daoud Sheban, Einav Laser, Matthias P Kramer, Ronen Shteinvil, Guoyun Chen, Angham Ibraheem, Vera Sysoeva, Vered Fishbain-Yoskovitz, Gayatree Mohapatra, Anat Abramov, Sandy Shimshi, Kseniia Ogneva, Madhurima Nandy, Sivan Amidror, Hadar Bootz-Maoz, Shanny H Kuo, Nili Dezorella, Assaf Kacen, Aaron Javitt, Gee W Lau, Nissan Yissachar, Zvi Hayouka, Yifat Merbl

Journal: Nature

PubMed ID: 40044870

Doi: 10.1038/s41586-025-08615-w

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Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody

Authors: Susanne H D Ständer, Cyril F Reboul, Sarah N Le, Daniel E Williams, Peter G Chandler, Mauricio G S Costa, David E Hoke, John D T Jimma, James Fodor, Gustavo Fenalti, Stuart I Mannering, Benjamin T Porebski, Peter Schofield, Daniel Christ, Malcolm Buckle, Sheena McGowan, Dominika Elmlund, Kasper D Rand, Ashley M Buckle

Journal: Nature Communications

PubMed ID: 40055307

Doi: 10.1038/s41467-025-57492-4

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Splenic red pulp macrophages eliminate the liver-resistant Streptococcus pneumoniae from the blood circulation of mice

Authors: Haoran An, Yijia Huang, Zhifeng Zhao, Kunpeng Li, Jingjing Meng, Xueting Huang, Xianbin Tian, Hongyu Zhou, Jiamin Wu, Qionghai Dai, Jing-Ren Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 40073120

Doi: 10.1126/sciadv.adq6399

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PNPLA6 regulates retinal homeostasis by choline through phospholipid turnover

Authors: Takashi Ono, Yoshitaka Taketomi, Takayoshi Higashi, Hiroyasu Sato, Chika Mochizuki-Ono, Yuki Nagasaki, Takashi Ueta, Takashi Miyai, Suzumi M Tokuoka, Yoshiya Oda, Yasumasa Nishito, Tomio Ono, Choji Taya, Satoru Arata, Sumiko Watanabe, Tomoyoshi Soga, Tetsuya Hirabayashi, Makoto Aihara, Makoto Murakami

Journal: Nature Communications

PubMed ID: 40082403

Doi: 10.1038/s41467-025-57402-8

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A CPC-shelterin-BTR axis regulates mitotic telomere deprotection

Authors: Diana Romero-Zamora, Samuel Rogers, Ronnie Ren Jie Low, Scott G Page, Blake J E Lane, Shunya Kosaka, Andrew B Robinson, Lucy French, Noa Lamm, Fuyuki Ishikawa, Makoto T Hayashi, Anthony J Cesare

Journal: Nature Communications

PubMed ID: 40097392

Doi: 10.1038/s41467-025-57456-8

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FGF2 Mediated USP42-PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Authors: Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li

Journal: Advanced Science

PubMed ID: 40091484

Doi: 10.1002/advs.202408724

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Orally delivered toxin–binding protein protects against diarrhoea in a murine cholera model

Authors: Marcus Petersson, Franz G Zingl, Everardo Rodriguez-Rodriguez, Jakob K H Rendsvig, Heidi Heinsøe, Emma Wenzel Arendrup, Natalia Mojica, Dario Segura Peña, Nikolina Sekulić, Ute Krengel, Monica L Fernández-Quintero, Timothy P Jenkins, Lone Gram, Matthew K Waldor, Andreas H Laustsen, Sandra Wingaard Thrane

Journal: Nature Communications

PubMed ID: 40108169

Doi: 10.1038/s41467-025-57945-w

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Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining

Authors: Yan Wang, Fuyuan Shen, Chen Zhao, Jiali Li, Wen Wang, Yamu Li, Jia Gan, Haojian Zhang, Xuefeng Chen, Qiang Chen, Fangyu Wang, Ying Liu, Yan Zhou

Journal: Nucleic Acids Res

PubMed ID: 40114375

Doi: 10.1093/nar/gkaf200

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Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1

Authors: Qinyu Zhu, Madeleine F Yaggi, Nikolaus Jork, Henning J Jessen, Melinda M Diver

Journal: Nature Communications

PubMed ID: 40113814

Doi: 10.1038/s41467-025-58076-y

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Machine Learning-Aided Identification of Fecal Extracellular Vesicle microRNA Signatures for Noninvasive Detection of Colorectal Cancer

Authors: Zhaowei Zhang, Xuyang Liu, Chuanyue Peng, Rui Du, Xiaoqin Hong, Jia Xu, Jiaming Chen, Xiaomin Li, Yujing Tang, Yuwei Li, Yang Liu, Chen Xu, Dingbin Liu

Journal: ACS Nano

PubMed ID: 40033785

Doi: 10.1021/acsnano.4c16698

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GPR132 regulates the function of NK cells through the Gαs/CSK/ZAP70/NF-κB signaling pathway as a potential immune checkpoint

Authors: Xinhui Hui, Min Xue, Yaojun Ren, Yiran Chen, Xuenan Chen, Muhammad Asad Farooq, Yuzhou Ji, Weirong Zhan, Yunhe Huang, Bingtan Du, Jie Yao, Yixin Duan, Wenzheng Jiang

Journal: Sci Adv

PubMed ID: 40043109

Doi: doi/10.1126/sciadv.adr9395

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Manganese-Driven Plasmid Nanofibers Formed In Situ for Cancer Gene Delivery and Metalloimmunotherapy

Authors: Jiexin Li, Ruiqi Yang, Chen Zhang, Jonathan F Lovell, Yumiao Zhang

Journal: J Am Chem Soc

PubMed ID: 40065259

Doi: 10.1021/jacs.4c18511

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Meiotic crossovers revealed by differential visualization of homologous chromosomes using enhanced haplotype oligo-painting in cucumber

Authors: Yafeng Wu，Zixuan Chen，Fengxiang Chen，Juan Su，Jianyu Han，Songqin Liu

Journal: Plant Biotechnol J

PubMed ID: 39661709

Doi: 10.1111/pbi.14546

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Examining the Role of Threonine Phosphorylation in Ubiquitin’s Function Using Chemical Protein Synthesis

Authors: Bingji Wang, Chuntong Li, Fangyu Zhao, Luyu Shi, Xu Li, Yijie Liu, Shuzhe Sun, Ligong Yuan, Maoshen Sun, Yingyue Zhang, Jing Shi, Lu-Jun Liang

Journal: JACS Au

Doi: doi/10.1021/jacsau.5c00067

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Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants

Authors: Shouya Feng, Matthew C Wierzbowski, Katja Hrovat-Schaale, Andreas Dumortier, Yaoyuan Zhang, Maria Zyulina, Paul J Baker, Thomas Reygaerts, Annemarie Steiner, Dominic De Nardo, Dhanya Lakshmi Narayanan, Florian Milhavet, Alberto Pinzon-Charry, Juan Ignacio Arostegui, Raju P Khubchandani, Matthias Geyer, Guilaine Boursier, Seth L Masters

Journal: nature immunology

PubMed ID: 39930093

Doi: 10.1038/s41590-025-02088-9

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Network pharmacology analysis of Lanatoside C: molecular targets and mechanisms in the treatment of ulcerative colitis

Authors: Wenjing Zhu; Zhengjie Zhang; Xinyuan Wang

Journal: Frontiers in molecular biosciences

PubMed ID: 40191037

Doi: 10.3389/fmolb.2025.1552360

AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens

Authors: Chenkai Li; Darcy Sutherland; S. Austin Hammond; Chen Yang; Figali Taho; Lauren Bergman; Simon Houston; Ren L. Warren; Titus Wong; Linda M. N. Hoang; Caroline E. Cameron; Caren C. Helbing; Inanc Birol

Journal: BMC Genomics

PubMed ID: 35078402

Doi: 10.1186/s12864-022-08310-4

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A Modified Variant of Fasciola hepatica FhSAP-2 (mFhSAP-2) as a Recombinant Vaccine Candidate Induces High-Avidity IgG2c Antibodies and Enhances T Cell Activation in C57BL/6 Mice

Authors: Riseilly Ramos-Nieves; Albersy Armina-Rodriguez; Maria Del Mar Figueroa-Gispert; Ghalib Figueroa-Qui ones; Carlimar Ocasio-Malav ; Ana M. Espino

Journal: Vaccines

PubMed ID: 40432154

Doi: 10.3390/vaccines13050545

The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade

Authors: Yijian Qiu; Olivia T. Stamatatos; Qingting Hu; Jed de Ruiter Swain; Suzanne Russo; Ava Sann; Ana S. H. Costa; Sara Violante; David L. Spector; Justin R. Cross; Michael J. Lukey

Journal: Nature metabolism

PubMed ID: 39192144

Doi: 10.1038/s42255-024-01104-w

FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestries

Authors: Ambroise Wonkam, Kevin Esoh, Rachel M Levine, Valentina Josiane Ngo Bitoungui, Khuthala Mnika, Nikitha Nimmagadda, Erin A D Dempsey, Siana Nkya, Raphael Z Sangeda, Victoria Nembaware, Jack Morrice, Fujr Osman, Michael A Beer, Julie Makani, Nicola Mulder, Guillaume Lettre, Martin H Steinberg, Rachel Latanich, James F Casella, Daiana Drehmer, Dan E Arking, Emile R Chimusa, Jonathan S Yen, Gregory A Newby, Stylianos E Antonarakis

Journal: Nature Communications

PubMed ID: 40025045

Doi: 10.1038/s41467-025-57413-5

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Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity

Authors: Liora S Katz, Emira J Visser, Kathrin F Plitzko, Marloes A M Pennings, Peter J Cossar, Isabelle L Tse, Markus Kaiser, Luc Brunsveld, Christian Ottmann, Donald K Scott

Journal: Nature Communications

PubMed ID: 40025013

Doi: 10.1038/s41467-025-57241-7

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Blockade of ZMIZ1-GATA4 Axis Regulation Restores Youthfulness to Aged Cartilage

Authors: Jiho Nam, Hyunmin Woo, Jihye Yang, Seok Jung Kim, Kwang Pyo Lee, Ji Hoon Yu, Tae Joo Park, Seong-Il Eyun, Siyoung Yang

Journal: Advanced Science

PubMed ID: 40040621

Doi: 10.1002/advs.202404311

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