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OsPRMT6b balances plant growth and high temperature stress by feedback inhibition of abscisic acid signaling
Authors: Xin Jin, Qibing Lin, Xinyue Zhang, Shuang Zhang, Weiwei Ma, Peike Sheng, Limin Zhang, Minxi Wu, Xudong Zhu, Zhiwei Li, Bojuan Liu, Jiachang Wang, Yupeng Wang, Kun Dong, Ming Yu, Yulong Ren, Zhijun Cheng, Cailin Lei, Xiuping Guo, Xin Wang, Haiyang Wang, Fu-Qing Wu, Shanshan Zhu, Jianmin Wan
Journal: Nature Communications
PubMed ID: 40467572
Doi: 10.1038/s41467-025-60350-y
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Mechanism of DNA degradation by CBASS Cap5 endonuclease immune effector
Authors: Olga Rechkoblit, Daniela Sciaky, Mi Ni, Yangmei Li, Jithesh Kottur, Gang Fang, Aneel K Aggarwal
Journal: Nature Communications
PubMed ID: 40473611
Doi: 10.1038/s41467-025-60484-z
Products & Services: Gene Synthesis   
mRNA-LNP vaccines against hepatitis B virus induce protective immune responses in preventive and chronic mouse challenge models
Authors: María José Limeres, Rocio Gambaro, Malin Svensson, Silvia Fraude-El Ghazi, Leah Pretsch, Daniel Frank, German A Islan, Ignacio Rivero Berti, Matthias Bros, Ying K Tam, Hiromi Muramatsu, Norbert Pardi, Stephan Gehring, Maximiliano L Cacicedo
Journal: Molecular Therapy
PubMed ID: 40518670
Doi: 10.1016/j.ymthe.2025.06.027
ELD1 mediates photoperiodic flowering via OsCCA1 alternative splicing and interacts with phytochrome signaling in rice
Authors: Liang Cai, Benyuan Hao, Zhuang Xu, Song Cui, Qianyun Wu, Jiyoung Lee, Haigang Hou, Yuan Hu, Liang Zhu, Jie Wang, Wen Li, Kongyou Chang, Weihao Shao, Shanshan Zhu, Xiangchao Gan, Chao Li, Ling Jiang, Yunlu Tian, Xi Liu, Shijia Liu, Liangming Chen, Haiyang Wang, Shirong Zhou, Jianmin Wan
Journal: Nature Communications
PubMed ID: 40537466
Doi: 10.1038/s41467-025-60839-6
Products & Services: Protein Electrophoresis and Western   
Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijacking
Authors: Esther González-Almela, Alvaro Castells-Garcia, François Le Dily, Manuel Fernández Merino, Davide Carnevali, Pol Cusco, Luciano Di Croce, Maria Pia Cosma
Journal: Nature Communications
PubMed ID: 40537528
Doi: 10.1038/s41467-025-60534-6
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Large-scale experimental assessment of variant effects on the structure and function of the citrate transporter SLC13A5
Authors: Wen-An Wang, Evandro Ferrada, Christoph Klimek, Tanja Osthushenrich, Aidan MacNamara, Tabea Wiedmer, Giulio Superti-Furga
Journal: SCIENCE ADVANCES
PubMed ID: 40577459
Doi: 10.1126/sciadv.adx3011
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Cholangiocytes contribute to hepatocyte regeneration after partial liver injury during growth spurt in zebrafish
Authors: Sema Elif Eski, Jiarui Mi, Macarena Pozo-Morales, Gabriel Garnik Hovhannisyan, Camille Perazzolo, Rita Manco, Imane Ez-Zammoury, Dev Barbhaya, Anne Lefort, Frédérick Libert, Federico Marini, Esteban N Gurzov, Olov Andersson, Sumeet Pal Singh
Journal: nature COMMUNICATION
PubMed ID: 40480975
Doi: 10.1038/s41467-025-60334-y
Products & Services: Gene Synthesis   
Histidine-Specific Modification of Chitin-Binding protein21 via Visible Light-Mediated C–H Functionalization and Protein Ligation
Authors: Xinliang Liu, Ping Wang and Farong Ye
Journal: CCS Chemistry
Doi: 10.31635/ccschem.024.202404864
Products & Services: Gene Synthesis   Plasmid DNA Preparation   
High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1
Authors: Judith Reeks, Pravin Mahajan, Mellissa Clark, Suzanna R Cowan, Elena Di Daniel, Christopher P Earl, Samantha Fisher, Rhian S Holvey, Scott M Jackson, Emyr Lloyd-Evans, Carmine M Morgillo, Paul N Mortenson, Marc O'Reilly, Caroline J Richardson, Patrick Schöpf, Daniel M Tams, Helen Waller-Evans, Simon E Ward, Stuart Whibley, Pamela A Williams, Christopher N Johnson
Journal: Structure
PubMed ID: 40532704
Doi: 10.1016/j.str.2025.05.014
Products & Services: Codon Optimization   
Host protein ARF1 is a proviral factor for SARS-CoV-2 and a candidate broad-spectrum therapeutic target
Authors: Cunhuan Zhang, Yuan-Qin Min, Heng Xue, Haiyan Zhang, Kunpeng Liu, Yichao Tian, Ziying Yang, Zihan Zhao, Hang Yang, Chao Shan, Xiulian Sun & Yun-Jia Ning
Journal: nature COMMUNICATION
Doi: 10.1038/s41467-025-61431-8
Products & Services: Peptide Synthesis   
Patch-Clamp-like Micropipette Electrode with Exterior and Interior Interfaces for Simultaneous Monitoring of Extracellular and Intracellular Serotonin across Neuron
Authors: Jie Liu, Qin Zhou, Yuandong Liu,Yang Tian
Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Doi: 10.1002/anie.202504408
Products & Services: Gene Synthesis   
An Insect Salivary Sheath Protein Triggers Plant Resistance to Insects and Pathogens as a Conserved HAMP
Authors: Liangxuan Qi, Jing Li, Shuai Li, Jing Li, Han Wang, Lei Yang, Xinyang Tan, Zhichang Zhao, Guanghua Luo, Maofeng Jing, Ary A Hoffmann, Jichao Fang, Rui Ji
Journal: Advanced Science
PubMed ID: 40167256
Doi: 10.1002/advs.202415474
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Cathepsin L-dependent positive selection shapes clonal composition and functional fitness of CD4+ T cells
Authors: Elisabetta Petrozziello, Amina Sayed, João A Freitas, Christine Federle, Jelena Nedjic, Sarina Ravens, Batuhan Akçabozan, Anna M Schulz, Dietmar Zehn, Marc Schmidt-Supprian, Reinhard Obst, Immo Prinz, Martijn Verdoes, Jan Kisielow, Thomas Reinheckel, Tobias Straub, Stephen R Daley, Ludger Klein
Journal: nature immunology
PubMed ID: 40514418
Doi: 10.1038/s41590-025-02182-y
Products & Services: Peptide Synthesis   
De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS
Authors: Wenfeng Zhao, Guofeng Chen, Jian He, Xiaofang Shen, Muya Xiong, Liwei Xiong, Zhihao Qi, Hang Xie, Wanchen Li, Jiameng Li, Huixia Dou, Hangchen Hu, Haixia Su, Qiang Shao, Minjun Li, Hongbin Sun, Yechun Xu
Journal: Nature Communications
PubMed ID: 40461475
Doi: 10.1038/s41467-025-60297-0
Products & Services: Gene Synthesis   
Substrate-based discovery of α-hydroxycarboxylic acid derivatives as potential herbicides targeting dihydroxyacid dehydratase
Authors: Bo He, Yanhao Hu, Dongshan Liu, Xin Zang, Xu He, Wang Chen, Jingfang Yang, Mingfeng Feng, Ping Chen, Lirong Wei, Yu Li, Wei Yan, Jun Li, Zhike Feng, Jiahai Zhou, Yonghao Ye
Journal: Nature Communications
PubMed ID: 40467578
Doi: 10.1038/s41467-025-60489-8
Functional relocation of the maize chloroplast atpB gene to the nucleus restores photosynthetic competence to a gene-edited non-photosynthetic mutant
Authors: Venkata RamanaRao Mangu, Kelsey Jenkins, Anna Pratt, Kara A Boltz, Leila Pazouki, Alice Y Hui, Muruganantham Mookkan, Jeffrey M Staub
Journal: Plant Biotechnology Journal.
PubMed ID: 40467523
Doi: 10.1111/pbi.70175
Products & Services: Catalog Antibodies   
Polymerised superparamagnetic antigen presenting cell lymphocyte capture for enriching tumour reactive T-cells and neoantigen identification
Authors: Chung-Yao Hsu, Po-Cheng Tsai, Jung-Chen Lin, Chen-Hsueh Pai, Yun-Jui Teng, Bing-Yu Yao, Cheng-Yin Fei, Gwo Harn Max Shiau, Leon Cw Lin, Sean Lo, Hung-Chih Yang, Che-Ming Jack Hu
Journal: Nature Communications
PubMed ID: 40456725
Doi: 10.1038/s41467-025-60321-3
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Constitutive down-regulation of liguleless alleles in sorghum drives increased productivity and water use efficiency
Authors: Nikhil Jaikumar, Truyen Quach, Zhengxiang Ge, Natalya Nersesian, Shirley J Sato, Scott M McCoy, Ming Guo, Andrew D B Leakey, Stephen P Long, Tom Elmo Clemente
Journal: Plant Biotechnology Journal.
PubMed ID: 40452217
Doi: 10.1111/pbi.70150
Products & Services: Gene Synthesis   
Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap-DNAs and Alleviating Pulmonary Fibrosis
Authors: Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen
Journal: Advanced Science
PubMed ID: 40539399
Doi: 10.1002/advs.202505357
Lysosomal Cathepsin S Escape Facilitates Near Infrared Light-Triggered Pyroptosis Via an Antibody-Indocyanine Green Conjugate
Authors: Fan Chen, Xue-Fei Tian, Teng Yang, Yu-Jie Dai, Da-Yuan Chen, Hong-Bo Chen, Takaya Shimura, Xin-Fang Li, Chu-Lin Sha, Qing Ji, Jun Cao, Mei-Yu Fang, Jin-Biao Shang, Jian-Min Fang, Ye Lu, Wei-Hui Zheng, Peng Guo, Wei-Hong Tan
Journal: Advanced Science
PubMed ID: 40539828
Doi: 10.1002/advs.202504851
Products & Services: Monoclonal Antibody Services   
Topoisomerase I Inhibition in ETV4-overexpressed Non-Small Cell Lung Cancer Promotes Replication and Transcription Mediated R-Loop Accumulation and DNA Damage
Authors: Jiaxi Zhang, Yan Wang, Shanhu Cao, Shelly M Xie, Bei Liu, Yimeng Li, Yuqi Hou, Xue Meng, Mingzhu Ruan, Di Bu, Jia Kang, Ruxin Li, Lei Lou, Juan Wang, Lingxiao Xing
Journal: Advanced Science
PubMed ID: 40548893
Doi: 10.1002/advs.202409307
Products & Services: PCR Cloning and Subcloning   
Coordinated early immune response in the lungs is required for effective control of SARS-CoV-2 replication
Authors: Klara Lenart, Hendrik Feuerstein, Mariana Prado Marmorato, Laura Perez Vidakovics, Gerald McInerney, Mimi Guebre-Xabier, Jessica F Trost, Bengt Eriksson, Gale Smith, Nita Patel, Karin Loré
Journal: Nature Communications
PubMed ID: 40562777
Doi: 10.1038/s41467-025-60885-0
Products & Services: Gene Synthesis   
Single-Cell and Spatial Transcriptomic Profiling of Penile Squamous Cell Carcinoma Reveals Dynamics of Tumor Differentiation and Immune Microenvironment
Authors: Hongjian Song, Zhichao Tong, Guixiang Xie, Yaowei Li, Yubo Zhao, Fengpu Fan, Zongzheng Yang, Qing Shi, Qian Zhang, Feng Wen, Hongxue Meng, Haonan Li, Pengyu Guo, Dayong Hou, Zhenwei Zhang, Zhihao Yin, Ziyi Liu, Jianwei Wang, Peng Zhang, Peng Dai, Changfu Li, Lichen Teng, Yangyang Xu, Dexin Ding, Tao Xu, Jianzhang Li, Yongsheng Chen, Yu Qiu, XiaoWei Hu, Wentao Liu, Liang Wu, Roman Nawroth, Guibo Li, Hang Su, Ziqing Deng, Ziqi Wang, Di Wang, Wanhai Xu
Journal: Advanced Science
PubMed ID: 40470730
Doi: 10.1002/advs.202500216
Products & Services: PCR Cloning and Subcloning   
Synthetic biology-driven induction of mature TLS formation enhances antitumor immunity in colorectal cancer
Authors: Ze Mi, Juan Chen, Zhewen Zhang, Jiahao Liu, Yiyi Lei, Hongpei Tan, Wei Li, Xiaoyuan Chen, Pengfei Rong
Journal: SCIENCE ADVANCES
PubMed ID: 40531967
Doi: 10.1126/scitranslmed.ado8395
Products & Services: DNA Sequencing   
Chemokines kill bacteria without triggering antimicrobial resistance by binding anionic phospholipids
Authors: Sergio M Pontejo, Sophia Martinez, Allison Zhao, Kevin Barnes, Jaime de Anda, Haleh Alimohamadi, Ernest Y Lee, Acacia F Dishman, Brian F Volkman, Gerard C L Wong, David N Garboczi, Angela Ballesteros, Philip M Murphy
Journal: SCIENCE ADVANCES
PubMed ID: 40479071
Doi: 10.1126/sciadv.ads2675
Products & Services: Plasmid DNA Preparation   
Assembly and the gating mechanism of the Pel exopolysaccharide export complex PelBC of Pseudomonas aeruginosa
Authors: Marius Benedens, Cristian Rosales-Hernandez, Sabine A P Straathof, Jennifer Loschwitz, Otto Berninghausen, Giovanni Maglia, Roland Beckmann, Alexej Kedrov
Journal: Nature Communications
PubMed ID: 40473691
Doi: 10.1038/s41467-025-60605-8
Products & Services: Gene Synthesis   
The pioneer transcription factor Zelda facilitates the exit from regeneration and restoration of patterning in Drosophila
Authors: Anish Bose, Keaton Schuster, Chandril Kodali, Surabhi Sonam, Rachel K Smith-Bolton
Journal: SCIENCE ADVANCES
PubMed ID: 40479065
Doi: 10.1126/sciadv.ads5743
Products & Services: PCR Cloning and Subcloning   
Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI
Authors: Edward D B Lopatto, Jesús M Santiago-Borges, Denise A Sanick, Sameer Kumar Malladi, Philippe N Azimzadeh, Morgan W Timm, Isabella F Fox, Aaron J Schmitz, Jackson S Turner, Shaza M Sayed Ahmed, Lillian Ortinau, Nathaniel C Gualberto, Jerome S Pinkner, Karen W Dodson, Ali H Ellebedy, Andrew L Kau, Scott J Hultgren
Journal: SCIENCE ADVANCES
PubMed ID: 40540557
Doi: 10.1126/sciadv.adw0698
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Molecular basis of the hepatobiliary tropism of typhoid toxin promoting Salmonella pathogenicity
Authors: Hwa Young Kim, Gi Young Lee, Andrew J Thompson, Ryan McBride, Dah-Jiun Fu, James C Paulson, Jeongmin Song
Journal: SCIENCE ADVANCES
PubMed ID: 40479051
Doi: 10.1126/sciadv.adt2040
Products & Services: Catalog Antibodies   
ATP13A1 engages SEC61 to facilitate substrate-specific translocation
Authors: Xiaoyan Yang, Yi Li, Chengxi Yang, Tingting Li, Zhiyu Fang, Zhigang Feng, Jun Liao, Yan Zou
Journal: SCIENCE ADVANCES
PubMed ID: 40498833
Doi: 10.1126/sciadv.adt1346
Products & Services: Protein and Antibody Isolation   
HIV-1 binds dynein directly to hijack microtubule transport machinery
Authors: Somayesadat Badieyan, Drew Lichon, Sevnur Komurlu Keceli, Michael P Andreas, John P Gillies, Wang Peng, Jiong Shi, Morgan E DeSantis, Christopher R Aiken, Till Böcking, Tobias W Giessen, Edward M Campbell, Michael A Cianfrocco
Journal: SCIENCE ADVANCES
PubMed ID: 40532013
Doi: 10.1126/sciadv.adn6796
LPS-enriched interaction drives spectrum conversion in antimicrobial peptides: Design and optimization of AA16 derivatives for targeting gram-negative bacteria
Authors: Wanyang Xiao, Ruize Sun, Jietao Lou, Yanyan Xu, Xiaokun Li, Kaiyun Xin, Weijie Lu, Chenhui Sun, Tianbao Chen, Yitian Gao, Di Wu
Journal: Eur J Med Chem
PubMed ID: 40048797
Doi: 10.1016/j.ejmech.2025.117462
Products & Services: Peptide Synthesis   
Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation
Authors: Zixuan Mei, Kamuran Yilamu, Weiyu Ni, Panyang Shen, Nan Pan, Huasen Chen, Yingfeng Su, Lei Guo, Qunan Sun, Zhaomei Li, Dongdong Huang, Xiangqian Fang, Shunwu Fan, Haitao Zhang, Shuying Shen
Journal: nature COMMUNICATION
PubMed ID: 40425566
Doi: 10.1038/s41467-025-60037-4
Products & Services: Catalog Antibodies   Protein and Antibody Isolation   
MechanismsofaureobasidinA inhibition and drug resistance in a fungal IPC synthase complex
Authors: Xinyue Wu , Xin Gong , Tian Xie
Journal: nature COMMUNICATION
PubMed ID: 40442105
Doi: doi.org/10.1038/s41467-025-60423-y
Products & Services: Protein and Antibody Isolation   
DNA-Engineered Modular Nanovaccines Featuring Precise Topology for Enhanced Immunogenicity
Authors: Yanfei Qu, Dawei Wang, Yunlong Zhang, Fengyun Shen, Binghui Xia, Qin Xu, Qisheng Wang, Huating Kong, Ying Zhu, Lihua Wang, Itamar Willner, Xiurong Yang, Chunhai Fan, Lele Sun
Journal: ADVANCED MATERIALS
PubMed ID: 40371439
Doi: 10.1002/adma.202500577
Products & Services: Protein and Antibody Reagents   
Deep Proteomic Profiling of the Intra-Golgi Trafficking Intermediates
Authors: Farhana Taher Sumya , Walter S Aragon-Ramirez , Vladimir V Lupashin
Journal: Molecular biology of the cell
PubMed ID: 40397568
Doi: 10.1091/mbc.E24-12-0556
Products & Services: Gene Synthesis   
Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease
Authors: Peifen Lu, Hongxiu Yuan, Gang Wang, Yixi Dong, Runyu Zhao, Jia Man, Jianwei Jiao, Zhaoyin Wang, Jin Jiao
Journal: Theranostics
Doi: 10.7150/thno.111583
Products & Services: Protein and Antibody Isolation   
Engineering galactose oxidase for biocatalytic synthesis of 2-(furan-2-yl)-2-oxoacetic acid, a critical precursor of cefuroxime
Authors: Tong Zhang, Hao Wei, Yunju Zhang, Tengteng Qi, Kehao Yuan, Bin Wang, Ziyan Zhang, Liangqing Chen, Qinyuan Ma, Xiuzhen Gao
Journal: Journal Pre-proof
Doi: 10.1016/j.gresc.2025.05.010
Cnidaria XIAP activates caspase-mediated cell death
Authors: Yuan Chen, Meng Wu, Zihao Yuan, Qingyue Wang, Hang Xu, Li Sun
Journal: International Journal of Biological Macromolecules
PubMed ID: 40288723
Doi: doi.org/10.1016/j.ijbiomac.2025.143427
Products & Services: Protein and Antibody Isolation   
Multi-level ROS regulation to activate innate and adaptive immune therapies
Authors: Ke-Ke Feng, Cheng-Lei Li, Yi-Fan Tu, Shi-Cheng Tian, Rui Xiong, Bai-Sheng Sa, Jing-Wei Shao
Journal: Chemical Engineering Journal
Doi: doi.org/10.1016/j.cej.2025.163429
Products & Services: Gene Synthesis   
A rationally designed injury kidney targeting peptide library and its application in rescuing acute kidney injury
Authors: Yushuo Xiao, Zhijian Tong, Huidie Xu, Zhouyan Jia, Chen Wang, Yang Cao, Liangliang Song, Siyu Hao, Jing Yang, Yihao Zhou, Yunhao Xie, Peng Wu, Tong He, Yancai Wu, Robert B Petersen, Anlin Peng, Chun Zhang, Hong Chen, Ling Zheng, Kun Huang
Journal: SCIENCE ADVANCES
PubMed ID: 40315322
Doi: 10.1126/sciadv.adt3943
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Structural basis for hepatitis E virus neutralization by potent human antibodies
Authors: Luis M Molinos-Albert, Eduard Baquero, Cyril Planchais, Virginie Doceul, Hicham El Costa, Estelle Mottez, Vincent Mallet, Stanislas Pol, Matthew L Albert, Nicole Pavio, Cécile Alanio, Jordan D Dimitrov, Hugo Mouquet
Journal: SCIENCE ADVANCES
PubMed ID: 40333967
Doi: 10.1126/sciadv.adu8811
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A novel, covalent broad-spectrum inhibitor targeting human coronavirus Mpro
Authors: Jing Sun, Deheng Sun, Qi Yang, Dong Wang, Jingjing Peng, Hu Guo, Xiaoyu Ding, Zhao Chen, Bin Yuan, Yan A Ivanenkov, Jinwei Yuan, Bogdan A Zagribelnyy, Yiyun He, Jingyi Su, Ling Wang, Jielin Tang, Zhun Li, Rong Li, Taotao Li, Xiaoyu Hu, Xing Liang, Airu Zhu, Peilan Wei, Yaya Fan, Sang Liu, Jie Zheng, Xin Guan, Alex Aliper, Minglei Yang, Dmitry S Bezrukov, Zhanhong Xie, Victor A Terentiev, Guilin Peng, Daniil A Polykovskiy, Alexander S Malyshev, Maxim N Malkov, Qingsong Zhu, Alán Aspuru-Guzik, Xiao Ding, Xin Cai, Man Zhang, Jingxian Zhao, Nanshan Zhong, Feng Ren, Xinwen Chen, Alex Zhavoronkov, Jincun Zhao
Journal: Nature Communications
PubMed ID: 40374668
Doi: 10.1038/s41467-025-59870-4
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Interleukin-34-dependent perivascular macrophages promote vascular function in the brain
Authors: Hannah Van Hove, Chaim Glück, Wiebke Mildenberger, Ekaterina Petrova, Upasana Maheshwari, Philipp Häne, Victor Kreiner, Mitchell Bijnen, Caroline Mussak, Sebastian G Utz, Jeanne Droux, Florian Ingelfinger, Christian Ashworth, Sebastian A Stifter, Elsa Roussel, Iva Lelios, Marijne Vermeer, Sheng-Fu Huang, Quanyu Zhou, Zhenyue Chen, Charlotte Calvet, Soline Bourgeois, Johanna Schaffenrath, Daniel Razansky, Jean X Juang, Kenichi Asano, Pawel Pelczar, Sarah Mundt, Bruno Weber, Susanne Wegener, Sonia Tugues, Christian Stockmann, Burkhard Becher, Annika Keller, Mohamad El Amki, Melanie Greter
Journal: Immunity
PubMed ID: 40315842
Doi: 10.1016/j.immuni.2025.04.003
Products & Services: Gene Synthesis   
Biomimetic culture substrates for modelling homeostatic intestinal epithelium in vitro
Authors: Sorosh Abdollahi, Bahareh Zarin, Maryam Vatani, Fereshteh Vajhadin, Mohsen Hassani, Pezhman Jalali, Keekyoung Kim, Amir Sanati-Nezhad
Journal: Nature Communications
PubMed ID: 40316543
Doi: 10.1038/s41467-025-59459-x
Products & Services: Molecular Biology Reagents   
Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity
Authors: Zilong Zhao, Benxia Hu, Yalan Deng, Melinda Soeung, Jun Yao, Lanxin Bei, Yaohua Zhang, Pengju Gong, Lisa A Huang, Zhou Jiang, Jian Gao, Shuang Peng, Tina K Nguyen, Menuka Karki, Bora Lim, Cassian Yee, Jared K Burks, Qing Zhang, Li Ma, Jianjun Gao, Nizar M Tannir, Leng Han, Dihua Yu, Linghua Wang, Michael A Curran, Maria A Gubbiotti, Giannicola Genovese, Boyi Gan, Wenbo Li, Pavlos Msaouel, Liuqing Yang, Chunru Lin
Journal: Immunity
PubMed ID: 40359940
Doi: 10.1016/j.immuni.2025.04.020
Products & Services: Protein and Antibody Isolation   
Neuron-targeted gene therapy rescues multiple phenotypes of STXBP1-related disorders in mice and is well tolerated in nonhuman primates
Authors: Rangoli Aeran, Annie Tanenhaus, Sheila M S Sears, Nathan J Moerke, Adam Miller, Camille Artur, Yosr Bouhlal, Peter F Bove, Alexander J Diaz de Arce, Saki Shimizu, Jason Le, Keith Place, Dixon Hoffelt, Tselmeg Amarlkhagva, Jennifer Su, Ming Chen, Brooke A Babineau, John McLaughlin, Myat Soe, Warren Macdonald, I Winnie Lin, Dhruv Bole, Kristen M Valentine, Elizabeth Hallam, Puja Dhanota, Serena Liu, Steven A Tan, Ben Zhao, Raghavendra Hosur, Maria Candida Vila, Suresh Poda, Archana Belle, Stephanie Tagliatela
Journal: Molecular Therapy
PubMed ID: 40349107
Doi: 10.1016/j.ymthe.2025.05.011
TRIM23 mediates cGAS-induced autophagy in anti-HSV defense
Authors: Dhiraj Acharya, Zuberwasim Sayyad, Helene Hoenigsperger, Maximilian Hirschenberger, Matthew Zurenski, Kannan Balakrishnan, Junji Zhu, Sebastian Gableske, Jiro Kato, Shen-Ying Zhang, Jean-Laurent Casanova, Joel Moss, Konstantin M J Sparrer, Michaela U Gack
Journal: Nature Communications
PubMed ID: 40360474
Doi: 10.1038/s41467-025-59338-5
Import mechanism of peroxisomal proteins with an N-terminal signal sequence
Authors: Michael L Skowyra , Tom A Rapoport
Journal: Nature Cell Biology
PubMed ID: 40346349
Doi: 10.1038/s41556-025-01662-5
Products & Services: Peptide Synthesis   
Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila
Authors: Sabrina J Fletcher, Eugenia S Bardossy, Lorena Tomé-Poderti, Thomas Moss, Vanesa Mongelli, Lionel Frangeul, Hervé Blanc, Yann Verdier, Joelle Vinh, Shaeri Mukherjee, Maria-Carla Saleh
Journal: SCIENCE ADVANCES
PubMed ID: 40378201
Doi: 10.1126/sciadv.adv1286
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