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页码: 133/1027 每页显示数量

Strikingly Different Roles of SARS-CoV-2 Fusion Peptides Uncovered by Neutron Scattering

Authors: Andreas Santamaria, Krishna C Batchu, Olga Matsarskaia, Sylvain F Prévost, Daniela Russo, Francesca Natali, Tilo Seydel, Ingo Hoffmann, Valérie Laux, Michael Haertlein, Tamim A Darwish, Robert A Russell, Giacomo Corucci, Giovanna Fragneto, Armando Maestro, Nathan R Zaccai

Journal: J Am Chem Soc

PubMed ID: 35157798

Doi: 10.1021/jacs.1c09856

Products & Services: Peptide Synthesis

Telencephalic outputs from the medial entorhinal cortex are copied directly to the hippocampus

Authors: Sau Yee Tsoi, Merve Öncül, Ella Svahn, Mark Robertson, Zuzanna Bogdanowicz, Christina McClure, Gülşen Sürmeli

Journal: Elife

PubMed ID: 35188100

Doi: 10.7554/eLife.73162

Products & Services: PCR Cloning and Subcloning

A novel peptide-based electrochemical biosensor for breast cancer characterization over a poly 3-(3-aminophenyl) propionic acid matrix

Authors: Rafael da Fonseca Alves, Isabella Castro Martins, Diego Leoni Franco, Adriane das Graças Silva, Paula de Souza Santos, Luiz Ricardo Goulart, Yara Cristina de Paiva Maia, Alinne Tatiane Faria Silva, Thaise Gonçalves Araújo, Maria Del Pilar Taboada Sotomayor

Journal: Biosens Bioelectron

PubMed ID: 35217253

Doi: 10.1016/j.bios.2022.114081

Products & Services: DNA Sequencing

Performance evaluation of novel fluorescent-based lateral flow immunoassay (LFIA) for rapid detection and quantification of total anti-SARS-CoV-2 S-RBD binding antibodies in infected individuals

Authors: Farah M Shurrab, Nadin Younes, Duaa W Al-Sadeq, Na Liu, Hamda Qotba, Laith J Abu-Raddad, Gheyath K Nasrallah

Journal: Int J Infect Dis

PubMed ID: 35231609

Doi: 10.1016/j.ijid.2022.02.052

Products & Services: Catalog Antibody

Functional antibody-dependent cell mediated cytotoxicity (ADCC) responses to vaccine and circulating influenza strains following vaccination

Authors: Xuemin Chen, He-Ying Sun, Chun Yi Lee, Christina A Rostad, Jessica Trost, Rodrigo B Abreu, Michael A Carlock, Jason R Wilson, Shane Gansebom, Ted M Ross, David A Steinhauer, Evan J Anderson, Larry J Anderson

Journal: Virology

PubMed ID: 35255298

Doi: 10.1016/j.virol.2022.02.004

Products & Services: Plasmid DNA Preparation

Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor

Authors: Hongmao Sun, Nathan P Coussens, Carina Danchik, Leah M Wachsmuth, Mark J Henderson, Samarjit Patnaik, Matthew D Hall, Ashley L Molinaro, Dayle A Daines, Min Shen

Journal: J Chem Inf Model

PubMed ID: 35103473

Doi: 10.1021/acs.jcim.1c01188

Products & Services: Recombinant Antibody Expression

Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

Authors: John P Evans, Cong Zeng, Claire Carlin, Gerard Lozanski, Linda J Saif, Eugene M Oltz, Richard J Gumina, Shan-Lu Liu

Journal: Sci Transl Med

PubMed ID: 35166573

Doi: 10.1126/scitranslmed.abn8057

Products & Services: Custom Vector Construction

Dissolving Microneedle Delivery of a Prophylactic HPV Vaccine

Authors: Sayoni Ray, David M Wirth, Oscar A Ortega-Rivera, Nicole F Steinmetz, Jonathan K Pokorski

Journal: Biomacromolecules

PubMed ID: 35139303

Doi: 10.1021/acs.biomac.1c01345

Products & Services: Catalog Peptides

Discrepant serological findings in SARS-CoV-2 PCR negative, hospitalised patients with fever and acute respiratory symptoms during the pandemic

Authors: Gail Brenda Cross, Claire M Naftalin, Jinghao Nicholas Ngiam, Natasha Bagdasarian, Chek Meng Poh, Yun Shan Goh, Wan Ni Chia, Siti Naqiah Amrun, Sai Meng Tham, Hazel Teng, Rawan Alagha, Shoban Krishna Kumar, Shaun Shi Yan Tan, Lin Fa Wang, Paul Anantharajah Tambyah, Laurent Renia, Dale Fisher, Lisa F P Ng

Journal: J Med Virol

PubMed ID: 35171507

Doi: 10.1002/jmv.27656

Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1

Authors: Wallace H Liu, Robert E Miner, Brittany N Albaugh, Gene E Ananiev, Scott A Wildman, John M Denu

Journal: Biochemistry

PubMed ID: 35143176

Doi: 10.1021/acs.biochem.1c00698

Products & Services: Catalog Peptides

Tetrahymena thermophila granule lattice protein 3 improves solubility of sexual stage malaria antigens expressed in Escherichia coli

Authors: Cengiz Akkale, Donna Marie Cassidy-Hanley, Theodore G Clark

Journal: Protein Expr Purif

PubMed ID: 35134517

Doi: 10.1016/j.pep.2022.106060

Products & Services: GenParts™ DNA Fragments

Crp/fnr family protein binds to promoters of atxA and sodmn genes that regulate the expression of exotoxins in Bacillus anthracis

Authors: Divya Goel, Sudhir Kumar, Gopal Krishna Joshi, Prashant Rai, Rakesh Bhatnagar

Journal: Protein Expr Purif

PubMed ID: 35114377

Doi: 10.1016/j.pep.2022.106059

Products & Services: Recombinant Antibody Expression

Discrepant serological findings in SARS-CoV-2 PCR negative, hospitalised patients with fever and acute respiratory symptoms during the pandemic

Journal: J Med Virol

PubMed ID: 35171507

Doi: 10.1002/jmv.27656

Immunoaffinity monoliths for multiplexed extraction of preterm birth biomarkers from human blood serum in 3D printed microfluidic devices

Authors: Haifa M Almughamsi, Makella K Howell, Samuel R Parry, Joule E Esene, Jacob B Nielsen, Gregory P Nordin, Adam T Woolley

Journal: Analyst

PubMed ID: 35103723

Doi: 10.1039/d1an01365c

Products & Services: Recombinant Proteins

Higher SARS-CoV-2 Spike Binding Antibody Levels and Neutralization Capacity 6 Months after Heterologous Vaccination with AZD1222 and BNT162b2

Authors: Brigitte Müller-Hilke, Franz Mai, Michael Müller, Johann Volzke, Emil C Reisinger

Journal: Vaccines (Basel)

PubMed ID: 35214780

Doi: 10.3390/vaccines10020322

Products & Services: Catalog Peptides

Comparison of Neutralizing Antibody Responses at 6 Months Post Vaccination with BNT162b2 and AZD1222

Authors: Evangelos Terpos, Vangelis Karalis, Ioannis Ntanasis-Stathopoulos, Zoi Evangelakou, Maria Gavriatopoulou, Maria S Manola, Panagiotis Malandrakis, Despoina D Gianniou, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Biomedicines

PubMed ID: 35203547

Doi: 10.3390/biomedicines10020338

The Anticancer Effect of a Conjugated Antimicrobial Peptide Against Colorectal Cancer (CRC) Cells

Authors: Raed Obaid Saleh, Ihsan Naji Atiyah Essia, Saade Abdalkareem Jasim

Journal: J Gastrointest Cancer

PubMed ID: 35217999

Doi: 10.1007/s12029-021-00799-4

Products & Services: Peptide Synthesis

Calcium and integrin-binding protein 1-like interacting with an integrin α-cytoplasmic domain facilitates cellular immunity in Helicoverpa armigera

Authors: Ming-Ming Zhang, Ling-Ling Luo, Yu Liu, Gui-Jie Wang, Huan-Huan Zheng, Xu-Sheng Liu, Jia-Lin Wang

Journal: Dev Comp Immunol

PubMed ID: 35231466

Doi: 10.1016/j.dci.2022.104379

Products & Services: Recombinant Antibody Expression

Fitness benefits play a vital role in the retention of the Pi-ta susceptible alleles

Authors: Jia Liu, Suobing Zhang, Pengfei Xie, Long Wang, Jia-Yu Xue, Yanmei Zhang, Ruisen Lu, Yueyu Hang, Yue Wang, Xiaoqin Sun

Journal: Genetics

PubMed ID: 35143673

Doi: 10.1093/genetics/iyac019

Products & Services: Custom DNA/RNA Oligos

Impact of Superparamagnetic Iron Oxide Nanoparticles on THP-1 Monocytes and Monocyte-Derived Macrophages

Authors: Christina Polasky, Tim Studt, Ann-Kathrin Steuer, Kristin Loyal, Kerstin Lüdtke-Buzug, Karl-Ludwig Bruchhage, Ralph Pries

Journal: Front Mol Biosci

PubMed ID: 35211509

Doi: 10.3389/fmolb.2022.811116

Products & Services: Proteins, Expression, Isolation and Analysis

Circular dichroism spectroscopic assessment of structural changes upon protein thermal unfolding at contrasting pH: Comparison with molecular dynamics simulations

Authors: Ponciano García-Gutiérrez, Menandro Camarillo-Cadena, Liliana I Vera-Robles, Rafael A Zubillaga, Andrés Hernández-Arana

Journal: Spectrochim Acta A Mol Biomol Spectrosc

PubMed ID: 35245803

Doi: 10.1016/j.saa.2022.121039

Products & Services: Gene Synthesis

Overexpression of sonic hedgehog enhances the osteogenesis in rat ectomesenchymal stem cells

Authors: Weijiang Wu, Zhe Wang, Zhijian Zhang, Wenjing Yang, Xin Fan, Jili Xu, Zhiqiang Huang, Qixiang Shao

Journal: Cell Tissue Bank

PubMed ID: 35147838

Doi: 10.1007/s10561-022-09994-4

Products & Services: Plasmid DNA Preparation

Overexpression of sonic hedgehog enhances the osteogenesis in rat ectomesenchymal stem cells

Authors: Weijiang Wu, Zhe Wang, Zhijian Zhang, Wenjing Yang, Xin Fan, Jili Xu, Zhiqiang Huang, Qixiang Shao

Journal: Cell Tissue Bank

PubMed ID: 35147838

Doi: 10.1007/s10561-022-09994-4

Products & Services: Plasmid DNA Preparation

Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines

Authors: Noëmi Johanna Roos, Riccardo Vincenzo Mancuso, Gerda Mawududzi Sanvee, Jamal Bouitbir, Stephan Krähenbühl

Journal: Food Chem Toxicol

PubMed ID: 35182693

Doi: 10.1016/j.fct.2022.112869

Products & Services: Proteins, Expression, Isolation and Analysis

E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2

Authors: Stephanie N Langel, Francine L Kelly, David M Brass, Andrew E Nagler, Dylan Carmack, Joshua J Tu, Tatianna Travieso, Ria Goswami, Sallie R Permar, Maria Blasi, Scott M Palmer

Journal: Cell Death Discov

PubMed ID: 35169120

Doi: 10.1038/s41420-022-00855-3

Products & Services: Plasmid DNA Preparation

RNA interference targeting UL25 gene as a gene therapy approach against BHV-1

Authors: Elaheh Amjadimanesh, Azam Mokhtari, Behnaz Saffar

Journal: Res Vet Sci

PubMed ID: 35182967

Doi: 10.1016/j.rvsc.2022.02.007

Products & Services: Custom DNA/RNA Oligos

Structural characterization of the ANTAR antiterminator domain bound to RNA

Authors: James L Walshe, Rezwan Siddiquee, Karishma Patel, Sandro F Ataide

Journal: Nucleic Acids Res

PubMed ID: 35150565

Doi: 10.1093/nar/gkac074

Products & Services: Gene Synthesis

Structural characterization of the ANTAR antiterminator domain bound to RNA

Authors: James L Walshe, Rezwan Siddiquee, Karishma Patel, Sandro F Ataide

Journal: Nucleic Acids Res

PubMed ID: 35150565

Doi: 10.1093/nar/gkac074

Products & Services: Gene Synthesis

Elucidating the acid-base mechanisms underlying otolith overgrowth in fish exposed to ocean acidification

Authors: Garfield T Kwan, Martin Tresguerres

Journal: Sci Total Environ

PubMed ID: 35143791

Doi: 10.1016/j.scitotenv.2022.153690

Products & Services: Polyclonal Antibody Services

Finger stick blood test to assess postvaccination SARS-CoV-2 neutralizing antibody response against variants

Authors: Sing Mei Lim, Hoi Lok Cheng, Huan Jia, Patthara Kongsuphol, Bhuvaneshwari D/O Shunmuganathan, Ming Wei Chen, Say Yong Ng, Xiaohong Gao, Shuvan Prashant Turaga, Sascha P Heussler, Jyoti Somani, Sharmila Sengupta, Dousabel M Y Tay, Megan E McBee, Barnaby E Young, Paul A MacAry, Hadley D Sikes, Peter R Preiser

Journal: Bioeng Transl Med

PubMed ID: 35600666

Doi: 10.1002/btm2.10293

Regulation of integrin α5β1 conformational states and intrinsic affinities by metal ions and the ADMIDAS

Authors: Jordan M Anderson, Jing Li, Timothy A Springer

Journal: Mol Biol Cell

PubMed ID: 35108026

Doi: 10.1091/mbc.E21-11-0536

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Design of Synthetic Mammalian Promoters Using Highly Palindromic Subsequences

Authors: Polina Govorkova, Chee Ka Candice Lam, Kevin Truong

Journal: ACS Synth Biol

PubMed ID: 35225601

Doi: 10.1021/acssynbio.1c00600

Products & Services: PCR Cloning and Subcloning

Challenges of expressing recombinant human tissue factor as a secreted protein in

Authors: Mohammad Jalili-Nik, Mohammad Soukhtanloo, Majid Mojarrad, Mohammad Hadi Sadeghian, Baratali Mashkani

Journal: Prep Biochem Biotechnol

PubMed ID: 35133942

Doi: 10.1080/10826068.2021.2023823

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The protective effects of Mirtazapine against lipopolysaccharide (LPS)-induced brain vascular hyperpermeability

Authors: Yuehong Pu, Lei Zhao, Yao Xi, Yichun Xia, Yiming Qian

Journal: Bioengineered

PubMed ID: 35081868

Doi: 10.1080/21655979.2021.2024962

Products & Services: ORF cDNA Clones/MolecularCloud

Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics

Authors: Simon D Weaver, Naviya Schuster-Little, Rebecca J Whelan

Journal: Anal Methods

PubMed ID: 35175250

Doi: 10.1039/d1ay02145a

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Genome-wide identification and characterization of AINTEGUMENTA-LIKE (AIL) family genes in apple (Malus domestica Borkh)

Authors: Xiaolei Han, Kai Liu, Gaopeng Yuan, Shanshan He, Peihua Cong, Caixia Zhang

Journal: Genomics

PubMed ID: 35151838

Doi: 10.1016/j.ygeno.2022.110313

Products & Services: Protein Tools

NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Authors: Jia Li, Zhao Xu

Journal: Mol Med Rep

PubMed ID: 35191517

Doi: 10.3892/mmr.2022.12649

Products & Services: Custom DNA/RNA Oligos

Ecology and Diversity of Culturable Fungal Species Associated with Soybean Seedling Diseases in the Midwestern United States

Authors: Mirian F Pimentel, Ali Y Srour, Amanda J Warner, Jason P Bond, Carl A Bradley, John Rupe, Martin I Chilvers, J Alejandro Rojas, Janette L Jacobs, Christopher R Little, Alison E Robertson, Loren J Giesler, Dean Malvick, Kiersten Wise, Albert Tenuta, Ahmad M Fakhoury

Journal: J Appl Microbiol

PubMed ID: 35226387

Doi: 10.1111/jam.15507

Products & Services: PCR and Cloning

High-throughput split-protein profiling by combining transposon mutagenesis and regulated protein-protein interactions with deep sequencing

Authors: Kai Zhou, Thomas Litfin, Md Solayman, Huijun Zhao, Yaoqi Zhou, Jian Zhan

Journal: Int J Biol Macromol

PubMed ID: 35120933

Doi: 10.1016/j.ijbiomac.2022.01.173

Products & Services: Custom DNA/RNA Oligos

An insect antifreeze protein from Anatolica polita enhances the cryoprotection of Xenopus laevis eggs and embryos

Authors: Predrag Jevtić, K Wade Elliott, Shelby E Watkins, Jonathan A Sreter, Katarina Jovic, Ian B Lehner, Paul W Baures, John G Tsavalas, Daniel L Levy, Krisztina Varga

Journal: J Exp Biol

PubMed ID: 35014670

Doi: 10.1242/jeb.243662

Products & Services: Custom DNA/RNA Oligos

Ultrasensitive Label-Free DNA Detection Based on Solution-Gated Graphene Transistors Functionalized with Carbon Quantum Dots

Authors: Minghua Deng, Jinhua Li, Bichen Xiao, Zhanpeng Ren, Ziqin Li, Haiyang Yu, Jiashen Li, Jianying Wang, Zhaowei Chen, Xianbao Wang

Journal: Anal Chem

PubMed ID: 35147418

Doi: 10.1021/acs.analchem.1c05309

Products & Services: Gene Synthesis

The interplay of viral loads, clinical presentation, and serological responses in SARS-CoV-2 - Results from a prospective cohort of outpatient COVID-19 cases

Authors: Kerstin Puchinger, Noemi Castelletti, Raquel Rubio-Acero, Christof Geldmacher, Tabea M Eser, Flora Deák, Ivana Paunovic, Abhishek Bakuli, Elmar Saathoff, Alexander von Meyer, Alisa Markgraf, Philine Falk, Jakob Reich, Friedrich Riess, Philipp Girl, Katharina Müller, Katja Radon, Jessica Michelle Guggenbuehl Noller, Roman Wölfel, Michael Hoelscher, Inge Kroidl, Andreas Wieser, Laura Olbrich

Journal: Virology

PubMed ID: 35245784

Doi: 10.1016/j.virol.2022.02.002

Hydroxychloroquine for prophylaxis of COVID-19 in health workers: A randomized clinical trial

Authors: Jorge Rojas-Serrano, Angelica Margarita Portillo-Vásquez, Ireri Thirion-Romero, Joel Vázquez-Pérez, Fidencio Mejía-Nepomuceno, Alejandra Ramírez-Venegas, Karla Midori Pérez-Kawabe, Rogelio Pérez-Padilla

Journal: PLoS ONE

PubMed ID: 35139097

Doi: 10.1371/journal.pone.0261980

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Increased Fibrosis in a Mouse Model of Anti-Laminin 332 Mucous Membrane Pemphigoid Remains Unaltered by Inhibition of Aldehyde Dehydrogenase

Authors: Sabrina Patzelt, Manuela Pigors, Heiko Steenbock, Leonard Diel, Katharina Boch, Lenche Chakievska, Sven Künzel, Hauke Busch, Anke Fähnrich, Jürgen Brinckmann, Enno Schmidt

Journal: Front Immunol

PubMed ID: 35197965

Doi: 10.3389/fimmu.2021.812627

Products & Services: Proteins, Expression, Isolation and Analysis

High level SARS-CoV-2 nucleocapsid refolding using mild condition for inclusion bodies solubilization: Application of high pressure at pH 90

Authors: Rosa Maria Chura-Chambi, Alvaro Rossan de Brandão Prieto-da-Silva, Matheus Martins Di Lela, João Ezequiel Oliveira, Patricia Estima Antonia Abreu, Luciana Regina Meireles, Heitor Franco de Andrade Junior, Ligia Morganti

Journal: PLoS ONE

PubMed ID: 35113919

Doi: 10.1371/journal.pone.0262591

Products & Services: Proteins, Expression, Isolation and Analysis

The receptor CgIL-17R1 expressed in granulocytes mediates the CgIL-17 induced haemocytes proliferation in Crassostrea gigas

Authors: Wanqing Cao, Weilin Wang, Siqi Fan, Jialuo Li, Qing Li, Shasha Wu, Lingling Wang, Linsheng Song

Journal: Dev Comp Immunol

PubMed ID: 35183562

Doi: 10.1016/j.dci.2022.104376

Products & Services: Proteins, Expression, Isolation and Analysis

Genome-wide identification and functional characterization of gene family reveal their involvement in response to drought stress in

Authors: Guangzhen Shi, Xinxia Zhu

Journal: PeerJ

PubMed ID: 35186477

Doi: 10.7717/peerj.12883

Products & Services: Protein Tools

Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease

Authors: Gapisha Karunakaran, Yidai Yang, Véronique Tremblay, Zhibin Ning, Jade Martin, Amine Belaouad, Daniel Figeys, Joseph S Brunzelle, Patrick M Giguere, Alain Stintzi, Jean-François Couture

Journal: FEBS Lett

PubMed ID: 35122247

Doi: 10.1002/1873-3468.14295

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APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells

Authors: Yingying Liu, Xiaochuan Ma, Hui Yang, Xun Li, Yingli Ma, Brandon Ason, Suling Liu, Liaoyuan A Hu

Journal: Biochem J

PubMed ID: 35084016

Doi: 10.1042/BCJ20210813

Products & Services: Gene Synthesis

Trans-seeding of Alzheimer-related tau protein by a yeast prion

Authors: Martin Flach, Cedric Leu, Alfonso Martinisi, Zhiva Skachokova, Stephan Frank, Markus Tolnay, Henning Stahlberg, David T Winkler

Journal: Alzheimers Dement

PubMed ID: 35142027

Doi: 10.1002/alz.12581

Products & Services: Mutant Libraries

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