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Dissecting Molecular Phenotypes Through FACS-Based Pooled CRISPR Screens

Authors: Oriana Genolet, Liat Ravid Lustig, Edda G Schulz

Journal: Methods Mol Biol

PubMed ID: 35218528

Doi: 10.1007/7651_2021_457

Products & Services: Plasmid DNA Preparation

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity

Authors: Guillaume A Petit, Yaoqin Hong, Karrera Y Djoko, Andrew E Whitten, Emily J Furlong, Airlie J McCoy, Jacqueline M Gulbis, Makrina Totsika, Jennifer L Martin, Maria A Halili

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35234148

Doi: 10.1107/S2059798322000729

Products & Services: Bacterial Expression

PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

Authors: Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant

Journal: J Immunother Cancer

PubMed ID: 35140112

Doi: 10.1136/jitc-2021-003526

Products & Services: Catalog Peptides

Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation

Authors: Leena Halim, Kushal K Das, Daniel Larcombe-Young, Adam Ajina, Andrea Candelli, Reuben Benjamin, Richard Dillon, David M Davies, John Maher

Journal: Front Immunol

PubMed ID: 35222427

Doi: 10.3389/fimmu.2022.836549

Products & Services: Mutagenesis Services

Longitudinal analysis of antibody dynamics in COVID-19 convalescents reveals neutralizing responses up to 16 months after infection

Authors: Yang Yang, Minghui Yang, Yun Peng, Yanhua Liang, Jinli Wei, Li Xing, Liping Guo, Xiaohe Li, Jie Li, Jun Wang, Mianhuan Li, Zhixiang Xu, Mingxia Zhang, Fuxiang Wang, Yi Shi, Jing Yuan, Yingxia Liu

Journal: Nat Microbiol

PubMed ID: 35132197

Doi: 10.1038/s41564-021-01051-2

Products & Services: Gene Synthesis

Engineering laboratory/factory-specific phage-resistant strains of Escherichia coli by mutagenesis and screening

Authors: Qi Shen, Xiao-Ting Zhou, Qian Guo, Ya-Ping Xue, Yu-Guo Zheng

Journal: World J Microbiol Biotechnol

PubMed ID: 35128603

Doi: 10.1007/s11274-022-03239-y

Products & Services: Proteins, Expression, Isolation and Analysis

Engineering laboratory/factory-specific phage-resistant strains of Escherichia coli by mutagenesis and screening

Authors: Qi Shen, Xiao-Ting Zhou, Qian Guo, Ya-Ping Xue, Yu-Guo Zheng

Journal: World J Microbiol Biotechnol

PubMed ID: 35128603

Doi: 10.1007/s11274-022-03239-y

Products & Services: Proteins, Expression, Isolation and Analysis

FXYD domain containing ion transport regulator 5 (FXYD5) silencing promotes cell viability and alleviates inflammatory response in cerulein-induced AR42J cells by blocking JAK2/STAT3 signaling pathway

Authors: Licheng Ding, Jie Li

Journal: Bioengineered

PubMed ID: 35042436

Doi: 10.1080/21655979.2021.2023795

Products & Services: Gene Synthesis

Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies

Authors: Marta Ferraroni, Andrea Angeli, Simone Carradori, Claudiu T Supuran

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35234146

Doi: 10.1107/S2059798322000079

Products & Services: Codon Optimization

Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies

Authors: Marta Ferraroni, Andrea Angeli, Simone Carradori, Claudiu T Supuran

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35234146

Doi: 10.1107/S2059798322000079

Products & Services: Codon Optimization

CoronaVac and ChAdOx1 Vaccination and Gamma Infection Elicited Neutralizing Antibodies against the SARS-CoV-2 Delta Variant

Authors: Marcilio Jorge Fumagalli, Luiza Antunes Castro-Jorge, William Marciel de Souza, Patrick Orestes de Azevedo, Alana Witt Hansen, Ricardo Tostes Gazzinelli, Benedito Antônio Lopes da Fonseca, Fernando Rosado Spilki, Luiz Tadeu Moraes Figueiredo

Journal: Viruses

PubMed ID: 35215895

Doi: 10.3390/v14020305

Products & Services: Gene Synthesis

Genome-wide identification and characterization of aquaporins in mangrove plant Kandelia obovata and its role in response to the intertidal environment

Authors: Zejun Guo, Dongna Ma, Jing Li, Mingyue Wei, Ludan Zhang, Lichun Zhou, Xiaoxuan Zhou, Shanshan He, Lin Wang, Yingjia Shen, Qingshun Quinn Li, Hai-Lei Zheng

Journal: Plant Cell Environ

PubMed ID: 35141923

Doi: 10.1111/pce.14286

Products & Services: Protein Tools

Silencing of IGF2BP1 restrains ox-LDL-induced lipid accumulation and inflammation by reducing RUNX1 expression and promoting autophagy in macrophages

Authors: Mingxin Liu, Guizhou Tao, Yiming Cao, Yu Hu, Zhe Zhang

Journal: J Biochem Mol Toxicol

PubMed ID: 35179253

Doi: 10.1002/jbt.22994

Products & Services: Custom DNA/RNA Oligos

Backbone NMR resonance assignment of the intrinsically disordered UBact protein from Nitrospira nitrosa

Authors: Steven M Bonn, David Fushman

Journal: Biomol NMR Assign

PubMed ID: 35107780

Doi: 10.1007/s12104-022-10070-x

Products & Services: Custom Vector Construction

RNA modifications stabilize the tertiary structure of tRNAfMet by locally increasing conformational dynamics

Authors: Thomas Biedenbänder, Vanessa de Jesus, Martina Schmidt-Dengler, Mark Helm, Björn Corzilius, Boris Fürtig

Journal: Nucleic Acids Res

PubMed ID: 35137185

Doi: 10.1093/nar/gkac040

Products & Services: Plasmid DNA Preparation

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

Authors: Prasidda Khadka, Zachary J Reitman, Sophie Lu, Graham Buchan, Gabrielle Gionet, Frank Dubois, Diana M Carvalho, Juliann Shih, Shu Zhang, Noah F Greenwald, Travis Zack, Ofer Shapira, Kristine Pelton, Rachel Hartley, Heather Bear, Yohanna Georgis, Spandana Jarmale, Randy Melanson, Kevin Bonanno, Kathleen Schoolcraft, Peter G Miller, Alexandra L Condurat, Elizabeth M Gonzalez, Kenin Qian, Eric Morin, Jaldeep Langhnoja, Leslie E Lupien, Veronica Rendo, Jeromy Digiacomo, Dayle Wang, Kevin Zhou, Rushil Kumbhani, Maria E Guerra Garcia, Claire E Sinai, Sarah Becker, Rachel Schneider, Jayne Vogelzang, Karsten Krug, Amy Goodale, Tanaz Abid, Zohra Kalani, Federica Piccioni, Rameen Beroukhim, Nicole S Persky, David E Root, Angel M Carcaboso, Benjamin L Ebert, Christine Fuller, Ozgun Babur, Mark W Kieran, Chris Jones, Hasmik Keshishian, Keith L Ligon, Steven A Carr, Timothy N Phoenix, Pratiti Bandopadhayay

Journal: Nat Commun

PubMed ID: 35105861

Doi: 10.1038/s41467-022-28198-8

Products & Services: Gene Synthesis

Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lung

Authors: Xinxin Wang, Jie Luo, Zhiyuan Wen, Lei Shuai, Chong Wang, Gongxun Zhong, Xijun He, Huizhen Cao, Renqiang Liu, Jinying Ge, Ronghong Hua, Ziruo Sun, Xijun Wang, Jinliang Wang, Zhigao Bu

Journal: PLoS Pathog

PubMed ID: 35176124

Doi: 10.1371/journal.ppat.1010343

Products & Services: Proteins, Expression, Isolation and Analysis

E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2

Authors: Stephanie N Langel, Francine L Kelly, David M Brass, Andrew E Nagler, Dylan Carmack, Joshua J Tu, Tatianna Travieso, Ria Goswami, Sallie R Permar, Maria Blasi, Scott M Palmer

Journal: Cell Death Discov

PubMed ID: 35169120

Doi: 10.1038/s41420-022-00855-3

Products & Services: Plasmid DNA Preparation

Supramolecular assembly of chloroplast NADH dehydrogenase-like complex with photosystem I from Arabidopsis thaliana

Authors: Xiaodong Su, Duanfang Cao, Xiaowei Pan, Lifang Shi, Zhenfeng Liu, Luca Dall'Osto, Roberto Bassi, Xinzheng Zhang, Mei Li

Journal: Mol Plant

PubMed ID: 35123031

Doi: 10.1016/j.molp.2022.01.020

Products & Services: Gene Synthesis

Rapid, High Throughput, Automated Detection Of SARS-Cov-2 Neutralizing Antibodies Against Native-Like Vaccine And Delta Variant Spike Trimers

Authors: Narayanaiah Cheedarla, Hans Verkerke, Sindhu Potlapalli, Kaleb McLendon, Anamika Patel, Filipp Frank, Gregory Damhorst, Huixia Wu, William O'Sick, Daniel Graciaa, Fuad Hudaib, David Alter, Jeannette Bryksin, Eric Ortlund, Jeannette Guarner, Sara Auld, Sarita Shah, Wilbur Lam, Dawn Mattoon, Joseph Johnson, David Wilson, Madhav Dhodapkar, Sean Stowell, Andrew Neish, John Roback

Journal: Res Sq

PubMed ID: 35194599

Doi: 10.21203/rs.3.rs-1322411/v1

Products & Services: Mammalian Expression

Mesophyll conductance is unaffected by expression of Arabidopsis PIP1 aquaporins in the plasmalemma of Nicotiana

Authors: Victoria C Clarke, Baxter Massey, Aleu Mani George, John R Evans, Susanne von Caemmerer, Michael Groszmann

Journal: J Exp Bot

PubMed ID: 35184158

Doi: 10.1093/jxb/erac065

Products & Services: Gene Synthesis

Engineering of thick human functional myocardium via static stretching and electrical stimulation

Authors: Danielle Pretorius, Asher M Kahn-Krell, Wesley C LaBarge, Xi Lou, Jianyi Zhang

Journal: iScience

PubMed ID: 35243219

Doi: 10.1016/j.isci.2022.103824

Products & Services: Proteins, Expression, Isolation and Analysis

Construction and characterization of two SARS-CoV-2 minigenome replicon systems

Authors: Hu Zhang, Douglas K Fischer, Masahiro Shuda, Patrick S Moore, Shou-Jiang Gao, Zandrea Ambrose, Haitao Guo

Journal: J Med Virol

PubMed ID: 35137972

Doi: 10.1002/jmv.27650

Products & Services: ORF cDNA Clones/MolecularCloud

Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation

Authors: Monicah N Bwayi, Efren Garcia-Maldonado, Sergio C Chai, Boer Xie, Shirish Chodankar, Andrew D Huber, Jing Wu, Kavya Annu, William C Wright, Hyeong-Min Lee, Jayaraman Seetharaman, Jingheng Wang, Cameron D Buchman, Junmin Peng, Taosheng Chen

Journal: Nucleic Acids Res

PubMed ID: 35212371

Doi: 10.1093/nar/gkac133

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Expression and characterization of a novel lytic polysaccharide monooxygenase, PdLPMO9A, from the edible fungus Pleurotus djamor and its synergistic interactions with cellulase in corn straw biomass saccharification

Authors: Yanli Li, Tongbing Li, Juntong Guo, Gang Wang, Guang Chen

Journal: Bioresour Technol

PubMed ID: 35121098

Doi: 10.1016/j.biortech.2022.126792

Products & Services: Recombinant Antibody Expression

The function of glucose metabolism in embryonic diapause of annual killifish

Authors: Xiaowen Gao, Tianyi Cai, Yongtong Lin, Rui Zhu, Wenxin Hao, Shuming Guo, Guangfu Hu

Journal: Comp Biochem Physiol Part D Genomics Proteomics

PubMed ID: 35149343

Doi: 10.1016/j.cbd.2022.100965

Products & Services: Recombinant Proteins

Anti-Neuronal Nuclear Antibody 3 Autoimmunity Targets Dachshund Homolog 1

Authors: Anastasia Zekeridou, Binxia Yang, Vanda A Lennon, Yong Guo, Liang Wu, Claudia F Lucchinetti, Andrew McKeon, Sean J Pittock, Eoin P Flanagan

Journal: Ann Neurol

PubMed ID: 35150165

Doi: 10.1002/ana.26320

Products & Services: Plasmid DNA Preparation

The protective effects of Mirtazapine against lipopolysaccharide (LPS)-induced brain vascular hyperpermeability

Authors: Yuehong Pu, Lei Zhao, Yao Xi, Yichun Xia, Yiming Qian

Journal: Bioengineered

PubMed ID: 35081868

Doi: 10.1080/21655979.2021.2024962

Products & Services: ORF cDNA Clones/MolecularCloud

Characterization, mRNA expression profile, subcellular distribution and association analysis with piglet diarrhea of porcine matrix metallopeptidase 7 (pMMP7)

Authors: Buyue Niu, Lu Liu, Zhihua Chen, Mingxing Kou, Xiuqin Yang, Yuan Sun, Shengwei Di, Xibiao Wang, Jiancheng Cai, Dongchun Guo

Journal: Gene

PubMed ID: 35182673

Doi: 10.1016/j.gene.2022.146319

Products & Services: Protein Tools

Serum TK1 protein and C-reactive protein correlate to treatment response and predict survival in dogs with hematologic malignancies

Authors: S Saellström, H Sharif, K K Jagarlamudi, H Rönnberg, L Wang, S Eriksson

Journal: Res Vet Sci

PubMed ID: 35245727

Doi: 10.1016/j.rvsc.2022.02.019

Products & Services: Catalog Peptides

Human cardiac myosin-binding protein C phosphorylation- and mutation-dependent structural dynamics monitored by time-resolved FRET

Authors: Rhye-Samuel Kanassatega, Thomas A Bunch, Victoria C Lepak, Christopher Wang, Brett A Colson

Journal: J Mol Cell Cardiol

PubMed ID: 35227736

Doi: 10.1016/j.yjmcc.2022.02.005

Products & Services: GenParts™ DNA Fragments

Cathepsin B inhibitor alleviates Th1, Th17, and Th22 transcription factor signaling dysregulation in experimental autoimmune encephalomyelitis

Authors: Mushtaq A Ansari, Ahmed Nadeem, Musaad A Alshammari, Sabry M Attia, Saleh A Bakheet, Mohammad R Khan, Thamer H Albekairi, Abdullah F Alasmari, Khaled Alhosaini, Faleh Alqahtani, Haneen A Al-Mazroua, Sheikh F Ahmad

Journal: Exp Neurol

PubMed ID: 35122866

Doi: 10.1016/j.expneurol.2022.113997

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Polycystin-1 and hydrostatic pressure are implicated in glioblastoma pathogenesis in vitro

Authors: Ilianna Zoi, Antonios N Gargalionis, Kostas A Papavassiliou, Narjes Nasiri-Ansari, Christina Piperi, Efthimia K Basdra, Athanasios G Papavassiliou

Journal: J Cell Mol Med

PubMed ID: 35106909

Doi: 10.1111/jcmm.17212

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ROCK2 Polymorphism and Expression Contribute to Increased Susceptibility and Poor Prognosis in Hepatocellular Carcinoma

Authors: Lifeng Qin, Xin Liu, Li'na Lan, Xiaoping Lv

Journal: Int J Gen Med

PubMed ID: 35173468

Doi: 10.2147/IJGM.S343968

Products & Services: GenParts™ DNA Fragments

Safety and immunogenicity of heterologous and homologous inactivated and adenoviral-vectored COVID-19 vaccine regimens in healthy adults: a prospective cohort study

Authors: Nasamon Wanlapakorn, Nungruthai Suntronwong, Harit Phowatthanasathian, Ritthideach Yorsaeng, Preeyaporn Vichaiwattana, Thanunrat Thongmee, Chompoonut Auphimai, Donchida Srimuan, Thaksaporn Thatsanatorn, Suvichada Assawakosri, Sitthichai Kanokudom, Yong Poovorawan

Journal: Hum Vaccin Immunother

PubMed ID: 35209809

Doi: 10.1080/21645515.2022.2029111

A broad-spectrum nanobody targeting the C-terminus of the hepatitis B surface antigen for chronic hepatitis B infection therapy

Authors: Yue Wang, Yaxian Mei, Zhenghong Ao, Yuanzhi Chen, Yichao Jiang, Xiaoqing Chen, Ruoyao Qi, Baorong Fu, Jixian Tang, Mujin Fang, Min You, Tianying Zhang, Quan Yuan, Wenxin Luo, Ningshao Xia

Journal: Antiviral Res

PubMed ID: 35183645

Doi: 10.1016/j.antiviral.2022.105265

Products & Services: Proteins, Expression, Isolation and Analysis

Ecology and Diversity of Culturable Fungal Species Associated with Soybean Seedling Diseases in the Midwestern United States

Authors: Mirian F Pimentel, Ali Y Srour, Amanda J Warner, Jason P Bond, Carl A Bradley, John Rupe, Martin I Chilvers, J Alejandro Rojas, Janette L Jacobs, Christopher R Little, Alison E Robertson, Loren J Giesler, Dean Malvick, Kiersten Wise, Albert Tenuta, Ahmad M Fakhoury

Journal: J Appl Microbiol

PubMed ID: 35226387

Doi: 10.1111/jam.15507

Products & Services: PCR and Cloning

Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening

Authors: Antonella Falconieri, Giovanni Minervini, Federica Quaglia, Geppo Sartori, Silvio C E Tosatto

Journal: Cancers (Basel)

PubMed ID: 35205757

Doi: 10.3390/cancers14041009

Products & Services: Plasmid DNA Preparation

Melanocortin receptor agonists suppress experimental autoimmune uveitis

Authors: Tat Fong Ng, Kaleb Dawit, Andrew W Taylor

Journal: Exp Eye Res

PubMed ID: 35196505

Doi: 10.1016/j.exer.2022.108986

Products & Services: Mammalian Expression

Charge-Modulated Accessibility of Tyrosine Residues for Silk-Elastin Copolymer Cross-Linking

Authors: Constancio Gonzalez-Obeso, Fredrik G Backlund, David L Kaplan

Journal: Biomacromolecules

PubMed ID: 35113522

Doi: 10.1021/acs.biomac.1c01192

Products & Services: Custom DNA/RNA Oligos

Photodynamic Activation of the Cholecystokinin 1 Receptor with Tagged Genetically Encoded Protein Photosensitizers: Optimizing the Tagging Patterns

Authors: Yuan Li, Zong Jie Cui

Journal: Photochem Photobiol

PubMed ID: 35211987

Doi: 10.1111/php.13611

Products & Services: Plasmid DNA Preparation

Photodynamic Activation of the Cholecystokinin 1 Receptor with Tagged Genetically Encoded Protein Photosensitizers: Optimizing the Tagging Patterns

Authors: Yuan Li, Zong Jie Cui

Journal: Photochem Photobiol

PubMed ID: 35211987

Doi: 10.1111/php.13611

Products & Services: Plasmid DNA Preparation

Fitness benefits play a vital role in the retention of the Pi-ta susceptible alleles

Authors: Jia Liu, Suobing Zhang, Pengfei Xie, Long Wang, Jia-Yu Xue, Yanmei Zhang, Ruisen Lu, Yueyu Hang, Yue Wang, Xiaoqin Sun

Journal: Genetics

PubMed ID: 35143673

Doi: 10.1093/genetics/iyac019

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A self-assembling nanoparticle vaccine targeting the conserved epitope of influenza virus hemagglutinin stem elicits a cross-protective immune response

Authors: Yongbo Qiao, Shuang Li, Shenghui Jin, Yi Pan, Yuhua Shi, Wei Kong, Yaming Shan

Journal: Nanoscale

PubMed ID: 35157751

Doi: 10.1039/d1nr08460g

Products & Services: Plasmid DNA Preparation

SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria-Infected Persons, Cambodia

Authors: Jessica Manning, Irfan Zaidi, Chanthap Lon, Luz Angela Rosas, Jae-Keun Park, Aiyana Ponce, Jennifer Bohl, Sophana Chea, Maria Karkanitsa, Sokunthea Sreng, Huy Rekol, Char Meng Chour, Dominic Esposito, Jeffery K Taubenberger, Matthew J Memoli, Kaitlyn Sadtler, Patrick E Duffy, Fabiano Oliveira

Journal: Emerg Infect Dis

PubMed ID: 35076009

Doi: 10.3201/eid2802.211725

Products & Services: Recombinant Proteins

Long noncoding RNASEH1-AS1 exacerbates the progression of non-small cell lung cancer by acting as a ceRNA to regulate microRNA-516a-5p/FOXK1 and thereby activating the Wnt/β-catenin signaling pathway

Authors: Chan Zhang, Jian Huang, Ke Lou, Hui Ouyang

Journal: Cancer Med

PubMed ID: 35166053

Doi: 10.1002/cam4.4509

Products & Services: Gene Synthesis

Non-ionic detergent assists formation of supercharged nanodiscs and insertion of membrane proteins

Authors: Frederik G Tidemand, Sara Blemmer, Nicolai T Johansen, Lise Arleth, Martin Cramer Pedersen

Journal: Biochim Biophys Acta Biomembr

PubMed ID: 35182589

Doi: 10.1016/j.bbamem.2022.183884

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LncRNA NORAD Mediates the Proliferation and Apoptosis of Diffuse Large-B-Cell Lymphoma via Regulation of miR-345-3p/TRAF6 Axis

Authors: Yang Li, Yuanyuan Lv, Jiangya Wang, Xiuli Zhu, Jian Chen, Wenting Zhang, Chuan Wang, Lian Jiang

Journal: Arch Med Res

PubMed ID: 35164979

Doi: 10.1016/j.arcmed.2022.01.004

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African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-B Signaling Pathway

Authors: Qi Wang , Luyu Zhou , Jiang Wang , Dan Su , Dahua Li , Yongkun Du , Guoyu Yang , Gaiping Zhang , Beibei Chu

Journal: Viruses

PubMed ID: 35215987

Doi: 10.3390/v14020394

Products & Services: Gene Synthesis

Parallel profiling of antigenicity alteration and immune escape of SARS-CoV-2 Omicron and other variants

Authors: Cong Sun , Yin-Feng Kang , Yuan-Tao Liu , Xiang-Wei Kong , Hui-Qin Xu , Dan Xiong , Chu Xie , Yi-Hao Liu , Sui Peng , Guo-Kai Feng , Zheng Liu , Mu-Sheng Zeng

Journal: Signal Transduct Target Ther

PubMed ID: 35136040

Doi: 10.1038/s41392-022-00910-6

Products & Services: Gene Synthesis Proteins, Expression, Isolation and Analysis

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