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Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles

Authors: Ashwanth C Francis, Anna Cereseto, Parmit K Singh, Jiong Shi, Eric Poeschla, Alan N Engelman, Christopher Aiken, Gregory B Melikyan

Journal: PLoS Pathog

PubMed ID: 35951676

Doi: 10.1371/journal.ppat.1010754

Products & Services: Protein and Antibody Isolation

Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase

Authors: Ryo Fujisawa, Cristian Polo Rivera, Karim P M Labib

Journal: Elife

PubMed ID: 35920641

Doi: 10.7554/eLife.76763

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Architecture and self-assembly of the jumbo bacteriophage nuclear shell

Authors: Thomas G Laughlin, Amar Deep, Amy M Prichard, Christian Seitz, Yajie Gu, Eray Enustun, Sergey Suslov, Kanika Khanna, Erica A Birkholz, Emily Armbruster, J Andrew McCammon, Rommie E Amaro, Joe Pogliano, Kevin D Corbett, Elizabeth Villa

Journal: Nature

PubMed ID: 35922510

Doi: 10.1038/s41586-022-05013-4

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Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene

Authors: Megan R Edwards, Olivia A Vogel, Hiroyuki Mori, Robert A Davey, Christopher F Basler

Journal: MBio

PubMed ID: 35997284

Doi: 10.1128/mbio.02243-22

Products & Services: Protein and Antibody Isolation

Free-energy landscape of two-state protein acylphosphatase with large contact order revealed by force-dependent folding and unfolding dynamics

Authors: Xuening Ma, Hao Sun, Haiyan Hong, Zilong Guo, Huanhuan Su, Hu Chen

Journal: Phys Rev E

PubMed ID: 36109974

Doi: 10.1103/PhysRevE.106.024404

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CAR-T Engager proteins optimize anti-CD19 CAR-T cell therapies for lymphoma

Authors: Lihe Su, Lan Wu, Roy R Lobb, Paul D Rennert, Christine Ambrose

Journal: Oncoimmunology

PubMed ID: 35990518

Doi: 10.1080/2162402X.2022.2111904

Products & Services: Mammalian Expression

Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts

Authors: Haarin Chun, James H Kurasawa, Philip Olivares, Ekaterina S Marakasova, Svetlana A Shestopal, Gabriela U Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O Obi, Ally K Smith, Patrick L Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K Strickland, Andrey G Sarafanov

Journal: J Thromb Haemost

PubMed ID: 35810466

Doi: 10.1111/jth.15817

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Efﬁcacy of glucose transporter inhibitors for the treatment of ERRα-overexpressed colorectal cancer

Authors: Miao Zhao, Cairong Xu, Hui Zhu

Journal: Acta Biochim Pol

PubMed ID: 36026615

Doi: 10.18388/abp.2020_5852

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T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition

Authors: En Cai, Casey Beppler, John Eichorst, Kyle Marchuk, Scott W Eastman, Matthew F Krummel

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35914144

Doi: 10.1073/pnas.2203247119

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A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif

Authors: Shan Wang, Sixing Lin, Qing Fang, Roland Gyampoh, Zhou Lu, Yingli Gao, David J Clarke, Kewen Wu, Laurent Trembleau, Yi Yu, Kwaku Kyeremeh, Bruce F Milne, Jioji Tabudravu, Hai Deng

Journal: Nat Commun

PubMed ID: 36028509

Doi: 10.1038/s41467-022-32774-3

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HIV-1-Infected CD4 T Cells Present MHC Class II-Restricted Epitope via Endogenous Processing

Authors: Mary M Addison, Gavin I Ellis, George J Leslie, Noah B Zawadzky, James L Riley, James A Hoxie, Laurence C Eisenlohr

Journal: J Immunol

PubMed ID: 36130133

Doi: 10.4049/jimmunol.2200145

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Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin

Authors: Yu Meng, Qing Wang, Zhe Ma, Weiyi Li, Kai Niu, Ting Zhu, Huixing Lin, Chengping Lu, Hongjie Fan

Journal: PLoS Pathog

PubMed ID: 35921364

Doi: 10.1371/journal.ppat.1010765

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Chemical and enzymatic modifications of 5-methylcytosine at the intersection of DNA damage, repair, and epigenetic reprogramming

Authors: Tuvshintugs Baljinnyam, Mark L Sowers, Chia Wei Hsu, James W Conrad, Jason L Herring, Linda C Hackfeld, Lawrence C Sowers

Journal: PLoS ONE

PubMed ID: 36037209

Doi: 10.1371/journal.pone.0273509

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A replicon RNA vaccine induces durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

Authors: Megan A Oâ Connor, David W Hawman, Kimberly Meade-White, Shanna Leventhal, Wenjun Song, Samantha Randall, Jacob Archer, Thomas B Lewis, Brieann Brown, Naoto Iwayama, Chul Ahrens, William Garrison, Solomon Wangari, Kathryn A Guerriero, Patrick Hanley, Jamie Lovaglio, Greg Saturday, Paul T Edlefsen, Amit Khandhar, Heinz Feldmann, Deborah Heydenburg Fuller, Jesse H Erasmus

Journal: biorxiv

PubMed ID: 35982677

Doi: 10.1101/2022.08.08.503239

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A novel method to purify small RNAs from human tissues for methylation analysis by LC-MS/MS

Authors: Rong Yang, Jianfeng Li, Yifan Wu, Xinli Jiang, Shuang Qu, Qiang Wang, Hongwei Liang, Ke Zen

Journal: Front Mol Biosci

PubMed ID: 36111135

Doi: 10.3389/fmolb.2022.949181

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α-Synuclein Interaction with Lipid Bilayer Discs

Authors: Marija Dubackic, Yun Liu, Elizabeth G Kelley, Crispin Hetherington, Michael Haertlein, Juliette M Devos, Sara Linse, Emma Sparr, Ulf Olsson

Journal: Langmuir

PubMed ID: 35952001

Doi: 10.1021/acs.langmuir.2c01368

Products & Services: Bacterial Expression

Characterization of Treponema denticola Major Surface Protein (Msp) by Deletion Analysis and Advanced Molecular Modeling

Authors: M Paula Goetting-Minesky, Valentina Godovikova, Wei Zheng, J Christopher Fenno

Journal: J Bacteriol

PubMed ID: 35913147

Doi: 10.1128/jb.00228-22

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Biophysical characterization of light-gated ion channels using planar automated patch clamp

Authors: Elena G Govorunova, Oleg A Sineshchekov, Leonid S Brown, John L Spudich

Journal: Front Mol Neurosci

PubMed ID: 36017077

Doi: 10.3389/fnmol.2022.976910

Products & Services: Mammalian Expression

The key molecular pattern BxCDP1 of induces plant immunity and enhances plant defense response two small peptide regions

Authors: Long-Jiao Hu, Xiao-Qin Wu, Tong-Yue Wen, Jian-Ren Ye, Yi-Jun Qiu, Lin Rui, Yan Zhang

Journal: Front Plant Sci

PubMed ID: 35991456

Doi: 10.3389/fpls.2022.937473

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A Defect in Lipoprotein Modification by Lgt Leads to Abnormal Morphology and Cell Death in Escherichia coli That Is Independent of Major Lipoprotein Lpp

Authors: S Legood, D Seng, I G Boneca, N Buddelmeijer

Journal: J Bacteriol

PubMed ID: 35938851

Doi: 10.1128/jb.00164-22

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The Use of Reproductive Indicators for Conservation Purposes: The Case Study of in Two Fully Protected Areas and Their Surrounding Zones (Central-Western Mediterranean)

Authors: Cristina Porcu, Laura Carugati, Andrea Bellodi, Pierluigi Carbonara, Alessandro Cau, Danila Cuccu, Faustina Barbara Cannea, Martina Francesca Marongiu, Antonello Mulas, Alessandra Padiglia, Noemi Pascale, Paola Pesci, Maria Cristina Follesa

Journal: Biology (Basel)

PubMed ID: 36009815

Doi: 10.3390/biology11081188

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Dynamicity and persistence of severe acute respiratory syndrome coronavirus-2 antibody response after double dose and the third dose with BBV-152 and AZD1222 vaccines: A prospective, longitudinal cohort study

Authors: Debaprasad Parai, Hari Ram Choudhary, Girish Chandra Dash, Susmita Behera, Narayan Mishra, Dipti Pattnaik, Sunil Kumar Raghav, Sanjeeb Kumar Mishra, Subrat Kumar Sahoo, Aparajita Swain, Ira Mohapatra, Matrujyoti Pattnaik, Aparnamayee Moharana, Sandhya Rani Jena, Ira Praharaj, Subhra Subhadra, Srikanta Kanungo, Debdutta Bhattacharya, Sanghamitra Pati

Journal: Front Microbiol

PubMed ID: 36016787

Doi: 10.3389/fmicb.2022.942659

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Exfoliative Toxin E, Oligomeric State and Flip of P186: Implications for Its Action Mechanism

Authors: Carolina Gismene, Jorge Enrique Hernández González, Angela Rocio Niño Santisteban, Andrey Fabricio Ziem Nascimento, Lucas Dos Santos Cunha, Fábio Rogério de Moraes, Cristiano Luis Pinto de Oliveira, Caio C Oliveira, Paola Jocelan Scarin Provazzi, Pedro Geraldo Pascutti, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti

Journal: Int J Mol Sci

PubMed ID: 36077258

Doi: 10.3390/ijms23179857

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Purification of Crimean Congo Hemorrhagic Fever Virus (CCHFV) Nucleocapsid Protein Using Detergent Gradient and Free Thawing

Authors: Austin Royster, Sheema Mir

Journal: Bio Protoc

PubMed ID: 36082370

Doi: 10.21769/BioProtoc.4483

Products & Services: Plasmid DNA Preparation

Tachykinin Neuropeptides and Amyloid β (25-35) Assembly: Friend or Foe?

Authors: Xikun Liu, Pritam Ganguly, Yingying Jin, Michael J Jhatro, Joan-Emma Shea, Steven K Buratto, Michael T Bowers

Journal: J Am Chem Soc

PubMed ID: 35917596

Doi: 10.1021/jacs.2c03845

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Platinum nanoparticles (PtNPs)-based CRISPR/Cas12a platform for detection of nucleic acid and protein in clinical samples

Authors: Jiajie Liang, Peijun Teng, Liangshan Hu, Guanbo He, Qifang Song, Ying Zhang, Bin Peng, Gan Li, Wei Xiao, Donglin Cao, Yong Tang

Journal: Anal Chim Acta

PubMed ID: 36038232

Doi: 10.1016/j.aca.2022.340203

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Rapid detection of Phytophthora cinnamomi based on a new target gene Pcinn13739

Authors: Zhenpeng Chen, Binbin Jiao, Jing Zhou, Haibin He, Tingting Dai

Journal: Frontiers in cellular and infection microbiology

Doi: 10.3389/fcimb.2022.923700

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HGT is widespread in insects and contributes to male courtship in lepidopterans

Authors: Yang Li , Zhiguo Liu , Chao Liu , Zheyi Shi , Lan Pang , Chuzhen Chen , Yun Chen , Ronghui Pan , Wenwu Zhou , Xue-Xin Chen , Antonis Rokas , Jianhua Huang , Xing-Xing Shen

Journal: Cell

PubMed ID: 35853453

Doi: doi.org/10.1016/j.cell.2022.06.014

Products & Services: Catalog Gene Editing

Regulation of Host Immune Response against Proteins via Computational mRNA Vaccine Design through Transcriptional Modification

Authors: Muhammad Naveed, Khizra Jabeen, Rubina Naz, Muhammad Saad Mughal, Ali A Rabaan, Muhammed A Bakhrebah, Fahad M Alhoshani, Mohammed Aljeldah, Basim R Al Shammari, Mohammed Alissa, Amal A Sabour, Rana A Alaeq, Maha A Alshiekheid, Mohammed Garout, Mohammed S Almogbel, Muhammad A Halwani, Safaa A Turkistani, Naveed Ahmed

Journal: Microorganisms

PubMed ID: 36014038

Doi: 10.3390/microorganisms10081621

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Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster

Authors: Julia R Port, Dylan H Morris, Jade C Riopelle, Claude Kwe Yinda, Victoria A Avanzato, Myndi G Holbrook, Trenton Bushmaker, Jonathan E Schulz, Taylor A Saturday, Kent Barbian, Colin A Russell, Rose Perry-Gottschalk, Carl I Shaia, Craig Martens, James O Lloyd-Smith, Robert J Fischer, Vincent J Munster

Journal: biorxiv

PubMed ID: 36032963

Doi: 10.1101/2022.08.15.504010

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Resolving the zinc binding capacity of honey bee vitellogenin and locating its putative binding sites

Authors: Vilde Leipart, Øyvind Enger, Diana Cornelia Turcu, Olena Dobrovolska, Finn Drabløs, Øyvind Halskau, Gro V Amdam

Journal: Insect Mol Biol

PubMed ID: 36054587

Doi: 10.1111/imb.12807

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Dysregulated naive B cells and de novo autoreactivity in severe COVID-19

Authors: Matthew C Woodruff, Richard P Ramonell, Natalie S Haddad, Fabliha A Anam, Mark E Rudolph, Tiffany A Walker, Alexander D Truong, Adviteeya N Dixit, Jenny E Han, Monica Cabrera-Mora, Martin C Runnstrom, Regina Bugrovsky, Jennifer Hom, Erin C Connolly, Igor Albizua, Vidhi Javia, Kevin S Cashman, Doan C Nguyen, Shuya Kyu, Ankur Singh Saini, Michael Piazza, Christopher M Tipton, Arezou Khosroshahi, Greg Gibson, Greg S Martin, Cheryl L Maier, Annette Esper, Scott A Jenks, F Eun-Hyung Lee, Ignacio Sanz

Journal: Nature

PubMed ID: 36044993

Doi: 10.1038/s41586-022-05273-0

Products & Services: Bacterial Expression

Riboflavin (Vitamin B2) Deficiency Induces Apoptosis Mediated by Endoplasmic Reticulum Stress and the CHOP Pathway in HepG2 Cells

Authors: Bo Zhang, Jun-Ting Cao, Yong-Bao Wu, Ke-Xin Gao, Ming Xie, Zheng-Kui Zhou, Jing Tang, Shui-Sheng Hou

Journal: Nutrients

PubMed ID: 36014863

Doi: 10.3390/nu14163356

Products & Services: Protein Electrophoresis and Western

Inhibitory effect of morin on aldolase 2 from Eimeria tenella

Authors: Junjing Hu, Mingfei Sun, Nanshan Qi, Asmaa M I Abuzeid, Juan Li, Haiming Cai, Minna Lv, Xuhui Lin, Shenquan Liao, Guoqing Li

Journal: Int J Parasitol Drugs Drug Resist

PubMed ID: 35952522

Doi: 10.1016/j.ijpddr.2022.07.002

Products & Services: Protein and Antibody Isolation

Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results

Authors: Christine D Palmer, Amy R Rappaport, Matthew J Davis, Meghan G Hart, Ciaran D Scallan, Sue-Jean Hong, Leonid Gitlin, Lauren D Kraemer, Sonia Kounlavouth, Aaron Yang, Lindsey Smith, Desiree Schenk, Mojca Skoberne, Kiara Taquechel, Martina Marrali, Jason R Jaroslavsky, Charmaine N Nganje, Elizabeth Maloney, Rita Zhou, Daniel Navarro-Gomez, Adrienne C Greene, Gijsbert Grotenbreg, Renee Greer, Wade Blair, Minh Duc Cao, Shawn Chan, Kyounghwa Bae, Alexander I Spira, Sameek Roychowdhury, David P Carbone, Brian S Henick, Charles G Drake, Benjamin J Solomon, Daniel H Ahn, Amit Mahipal, Steve B Maron, Benny Johnson, Raphael Rousseau, Roman Yelensky, Chih-Yi Liao, Daniel V T Catenacci, Andrew Allen, Andrew R Ferguson, Karin Jooss

Journal: Nat Med

PubMed ID: 35970920

Doi: 10.1038/s41591-022-01937-6

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Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity

Authors: Yvonne Joho, Vanessa Vongsouthi, Matthew A Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A Kaczmarski, Alessandro T Caputo, Santana Royan, Colin J Jackson, Albert Ardevol

Journal: Biochemistry

PubMed ID: 35951410

Doi: 10.1021/acs.biochem.2c00323

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Rabbit hemorrhagic disease virus VP60 protein expressed in recombinant swinepox virus self-assembles into virus-like particles with strong immunogenicity in rabbits

Authors: Changjin Liu, Min Lin, Huanyi Hu, Xiaolan Liu, Yanchao Bian, Xiaohua Huang, Xiaoxiang Li, Wenyang Yu, Feng Luo, Shunzhou Deng

Journal: Front Microbiol

PubMed ID: 35992711

Doi: 10.3389/fmicb.2022.960374

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Investigation of Transcript Variant 6 of as a Prognostic and Predictive Biomarker in Basal-Like MDA-MB-231 and MDA-MB-453 Cell Lines for Breast Cancer

Authors: Xin Zhang, Daniel O'Brien, Xiaohui Zhang

Journal: Oxid Med Cell Longev

PubMed ID: 36071863

Doi: 10.1155/2022/7078787

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TLNRD1 is a CCM complex component and regulates endothelial barrier integrity

Authors: Neil J. Ball; Sujan Ghimire; Gautier Follain; Ada O. Pajari; Diana Wurzinger; Monika Vaitkevi i t ; Alana R. Cowell; Bence Berki; Johanna Ivaska; Ilkka Paatero; Benjamin T. Goult; Guillaume Jacquemet

Journal: The Journal of cell biology

PubMed ID: 39013281

Doi: 10.1083/jcb.202310030

Expedient Synthesis of Ubiquitin-like Protein ISG15 Tools Through Chemo-Enzymatic Ligation Catalyzed by a Viral Protease Lbpro

Authors: Tian Wang , Chuntong Li , Meijing Wang , Jiachen Zhang , Qingyun Zheng , Lujun Liang , Guochao Chu , Xiaolin Tian , Haiteng Deng , Wei He , Lei Liu , Jinghong Li

Journal: Angew Chem Int Ed Engl

PubMed ID: 35962463

Doi: 10.1002/anie.202206205

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Enhancing the Catalytic Activity of Type II L-Asparaginase from Bacillus licheniformis through Semi-Rational Design

Authors: Yawen Zhou ,Linshu Jiao ,Juan Shen ,Huibing Chi ,Zhaoxin Lu ,Huawei Liu ,Fengxia Lu ,Ping Zhu

Journal: Int J Mol Sci

Doi: 10.3390/ijms23179663

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Dry powder inhalation technology for heart targeting applied to calcium phosphate nanoparticles loaded with active substances

Authors: Eride Quarta,Lorenzo Degli Esposti, Ruggero Bettini ,Fabio Sonvico ,Daniele Catalucci , Michele Iafisco ,Claudio De Luca ,Giovanna Trevisi ,Paolo Colombo ,Alessandra Rossi ,Francesca Buttini , Gaia Colombo

Journal: Drug Delivery Science and Technology

Doi: doi.org/10.1016/j.jddst.2022.103719

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Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides

Authors: Nayeli Escudero Castelán , Dean C Semmens , Luis Alfonso Yañez Guerra , Meet Zandawala , Mario Dos Reis , Susan E Slade , James H Scrivens , Cleidiane G Zampronio , Alexandra M Jones , Olivier Mirabeau , Maurice R Elphick

Journal: BMC Biol

PubMed ID: 36002813

Doi: 10.1186/s12915-022-01387-z

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The neurodevelopmental gene MSANTD2 belongs to a gene family formed by recurrent molecular domestication of Harbinger transposons at the base of vertebrates

Authors: Ema Etchegaray, Dominique Baas, Magali Naville, Zofia Haftek-Terreau, Jean Nicolas Volff

Journal: Mol Biol Evol

PubMed ID: 35980103

Doi: 10.1093/molbev/msac173

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Human Claudin-Derived Peptides Block the Membrane Fusion Process of Zika Virus and Are Broad Flavivirus Inhibitors

Authors: Jim Zoladek, Julien Burlaud-Gaillard, Maxime Chazal, Sophie Desgraupes, Patricia Jeannin, Antoine Gessain, Nathalie Pardigon, Mathieu Hubert, Philippe Roingeard, Nolwenn Jouvenet, Philippe V Afonso

Journal: Microbiol Spectr

PubMed ID: 36040168

Doi: 10.1128/spectrum.02989-22

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TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons

Authors: Wendy Wing Sze Yue, Lin Yuan, Joao M Braz, Allan I Basbaum, David Julius

Journal: Elife

PubMed ID: 35968676

Doi: 10.7554/eLife.80139

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Secretion of collagenases by Saccharomyces cerevisiae for collagen degradation

Authors: Han Xiao, Xiufang Liu, Yunzi Feng, Lin Zheng, Mouming Zhao, Mingtao Huang

Journal: Biotechnol Biofuels Bioprod

PubMed ID: 36031598

Doi: 10.1186/s13068-022-02186-y

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Preferential binding of DAP-PGs by major peptidoglycan recognition proteins found in cell-free hemolymph of Manduca sexta

Authors: Udeshika Kariyawasam, Mansi Gulati, Yang Wang, Haibo Bao, Tisheng Shan, Xiuru Li, Xiaolong Cao, Niranji Sumathipala, Yingxia Hu, Xiufeng Zhang, Geert-Jan Boons, Haobo Jiang

Journal: Insect Biochem Mol Biol

PubMed ID: 36007680

Doi: 10.1016/j.ibmb.2022.103827

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Development and application of a rapid all-in-one plasmid CRISPR-Cas9 system for iterative genome editing in Bacillus subtilis

Authors: Yu Zou, Lu Qiu, Aowen Xie, Wenyuan Han, Shangbo Zhang, Jinshan Li, Shumiao Zhao, Yingjun Li, Yunxiang Liang, Yongmei Hu

Journal: Microb Cell Fact

PubMed ID: 35999638

Doi: 10.1186/s12934-022-01896-0

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N1-methylpseudouridine found within COVID-19 mRNA vaccines produces faithful protein products

Authors: Kyusik Q Kim, Bhagyashri D Burgute, Shin-Cheng Tzeng, Crystal Jing, Courtney Jungers, Junya Zhang, Liewei L Yan, Richard D Vierstra, Sergej Djuranovic, Bradley S Evans, Hani S Zaher

Journal: Cell Rep

PubMed ID: 35988540

Doi: 10.1016/j.celrep.2022.111300

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