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encoding GDP-D-mannose pyrophosphorylase from celery enhanced the accumulation of ascorbic acid and resistance to drought stress in

Authors: Yan-Hua Liu, Hao Wang, Jie-Xia Liu, Sheng Shu, Guo-Fei Tan, Meng-Yao Li, Ao-Qi Duan, Hui Liu, Ai-Sheng Xiong

Journal: PeerJ

PubMed ID: 35233296

Doi: 10.7717/peerj.12976

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encoding GDP-D-mannose pyrophosphorylase from celery enhanced the accumulation of ascorbic acid and resistance to drought stress in

Authors: Yan-Hua Liu, Hao Wang, Jie-Xia Liu, Sheng Shu, Guo-Fei Tan, Meng-Yao Li, Ao-Qi Duan, Hui Liu, Ai-Sheng Xiong

Journal: PeerJ

PubMed ID: 35233296

Doi: 10.7717/peerj.12976

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Challenges of expressing recombinant human tissue factor as a secreted protein in

Authors: Mohammad Jalili-Nik, Mohammad Soukhtanloo, Majid Mojarrad, Mohammad Hadi Sadeghian, Baratali Mashkani

Journal: Prep Biochem Biotechnol

PubMed ID: 35133942

Doi: 10.1080/10826068.2021.2023823

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Higher SARS-CoV-2 Spike Binding Antibody Levels and Neutralization Capacity 6 Months after Heterologous Vaccination with AZD1222 and BNT162b2

Authors: Brigitte Müller-Hilke, Franz Mai, Michael Müller, Johann Volzke, Emil C Reisinger

Journal: Vaccines (Basel)

PubMed ID: 35214780

Doi: 10.3390/vaccines10020322

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A broad-spectrum nanobody targeting the C-terminus of the hepatitis B surface antigen for chronic hepatitis B infection therapy

Authors: Yue Wang, Yaxian Mei, Zhenghong Ao, Yuanzhi Chen, Yichao Jiang, Xiaoqing Chen, Ruoyao Qi, Baorong Fu, Jixian Tang, Mujin Fang, Min You, Tianying Zhang, Quan Yuan, Wenxin Luo, Ningshao Xia

Journal: Antiviral Res

PubMed ID: 35183645

Doi: 10.1016/j.antiviral.2022.105265

Products & Services: Proteins, Expression, Isolation and Analysis

Metal Dependence and Functional Diversity of Type I Cas3 Nucleases

Authors: Sining Sun, Zunyu He, Paul Jiang, Rishika Baral, Maria-Eirini Pandelia

Journal: Biochemistry

PubMed ID: 35184547

Doi: 10.1021/acs.biochem.1c00779

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Impact of the clinically approved Petasites hybridus extract Ze 339 on intestinal mechanisms involved in the handling of histamine

Authors: Lina G Mettler, Karin Brecht, Veronika Butterweck, Henriette E Meyer Zu Schwabedissen

Journal: Biomed Pharmacother

PubMed ID: 35149385

Doi: 10.1016/j.biopha.2022.112698

Products & Services: Proteins, Expression, Isolation and Analysis

Calcium and integrin-binding protein 1-like interacting with an integrin α-cytoplasmic domain facilitates cellular immunity in Helicoverpa armigera

Authors: Ming-Ming Zhang, Ling-Ling Luo, Yu Liu, Gui-Jie Wang, Huan-Huan Zheng, Xu-Sheng Liu, Jia-Lin Wang

Journal: Dev Comp Immunol

PubMed ID: 35231466

Doi: 10.1016/j.dci.2022.104379

Products & Services: Recombinant Antibody Expression

Aluminum nanoparticles deliver a dual-epitope peptide for enhanced anti-tumor immunotherapy

Authors: Shuting Bai, Hao Jiang, Yuanshuai Song, Yining Zhu, Ming Qin, Chunting He, Guangsheng Du, Xun Sun

Journal: J Control Release

PubMed ID: 35217098

Doi: 10.1016/j.jconrel.2022.02.027

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Comparison of Neutralizing Antibody Responses at 6 Months Post Vaccination with BNT162b2 and AZD1222

Authors: Evangelos Terpos, Vangelis Karalis, Ioannis Ntanasis-Stathopoulos, Zoi Evangelakou, Maria Gavriatopoulou, Maria S Manola, Panagiotis Malandrakis, Despoina D Gianniou, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Biomedicines

PubMed ID: 35203547

Doi: 10.3390/biomedicines10020338

The Outer Membrane Lipoprotein Tp0136 Stimulates Human Platelet Activation and Aggregation Through PAR1 to Enhance G/G Signaling

Authors: Qiu-Yan Xu, Yong-Jing Wang, Li-Rong Lin, Li-Li Liu, Tian-Ci Yang

Journal: Front Immunol

PubMed ID: 35296084

Doi: 10.3389/fimmu.2022.818151

Products & Services: Proteins, Expression, Isolation and Analysis

The Secreted Protein PA3611 Promotes Bronchial Epithelial Cell Epithelial-Mesenchymal Transition via Integrin αvβ6-Mediated TGF-β1-Induced p38/NF-κB Pathway Activation

Authors: Lei Shu, Sixia Chen, Shaoqing Lin, Huan Lin, Yan Shao, Jing Yao, Lili Qu, Yunshi Zhang, Xing Liu, Xingran Du, Kaili Deng, Xiaolin Chen, Ganzhu Feng

Journal: Front Microbiol

PubMed ID: 35197937

Doi: 10.3389/fmicb.2021.763749

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Antibody-Drug Conjugate Targeting c-Kit for the Treatment of Small Cell Lung Cancer

Authors: Kwang-Hyeok Kim, Jin-Ock Kim, Jeong-Yang Park, Min-Duk Seo, Sang Gyu Park

Journal: Int J Mol Sci

PubMed ID: 35216379

Doi: 10.3390/ijms23042264

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Vasoactive Intestinal Peptide Indirectly Elicits Pituitary LH Secretion Independent of GnRH in Female Zebrafish

Authors: Sakura Tanaka, Nilli Zmora, Berta Levavi-Sivan, Yonathan Zohar

Journal: Endocrinology

PubMed ID: 34978328

Doi: 10.1210/endocr/bqab264

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A truncated CC-NB-ARC gene TaRPP13L1-3D positively regulates powdery mildew resistance in wheat via the RanGAP-WPP complex-mediated nucleocytoplasmic shuttle

Authors: Xiangyu Zhang, Guanghao Wang, Xiaojian Qu, Mengmeng Wang, Huan Guo, Lu Zhang, Tingdong Li, Yajuan Wang, Hong Zhang, Wanquan Ji

Journal: Planta

PubMed ID: 35133503

Doi: 10.1007/s00425-022-03843-0

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Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis

Authors: Ya Yang, Yanfei Chen, Yalei Zhao, Feiyang Ji, Lingjian Zhang, Shima Tang, Sainan Zhang, Qingqing Hu, Zuhong Li, Fen Zhang, Qian Li, Lanjuan Li

Journal: Stem Cell Res Ther

PubMed ID: 35123555

Doi: 10.1186/s13287-022-02734-1

Products & Services: Proteins, Expression, Isolation and Analysis

Metabolic Division in an Coculture System for Efficient Production of Kaempferide

Authors: Zetian Qiu, Xue Liu, Jia Li, Bin Qiao, Guang-Rong Zhao

Journal: ACS Synth Biol

PubMed ID: 35167258

Doi: 10.1021/acssynbio.1c00510

Products & Services: Plasmid DNA Preparation

Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA

Authors: Fernando Rodriguez, Irina A Yushenova, Daniel DiCorpo, Irina R Arkhipova

Journal: Nat Commun

PubMed ID: 35228526

Doi: 10.1038/s41467-022-28471-w

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Grafting Watermelon Onto Pumpkin Increases Chilling Tolerance by Up Regulating to Increase Putrescine Biosynthesis

Authors: Junyang Lu, Fei Cheng, Yuan Huang, Zhilong Bie

Journal: Front Plant Sci

PubMed ID: 35242149

Doi: 10.3389/fpls.2021.812396

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The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature

Authors: Galen J Correy, Daniel W Kneller, Gwyndalyn Phillips, Swati Pant, Silvia Russi, Aina E Cohen, George Meigs, James M Holton, Stefan Gahbauer, Michael C Thompson, Alan Ashworth, Leighton Coates, Andrey Kovalevsky, Flora Meilleur, James S Fraser

Journal: biorxiv

PubMed ID: 35169801

Doi: 10.1101/2022.02.07.479477

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Nuclear morphogenesis: forming a heterogeneous nucleus during embryogenesis

Authors: Albert Tsai, Justin Crocker

Journal: Development

PubMed ID: 35142344

Doi: 10.1242/dev.200266

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Postvaccination antibody titres predict protection against COVID-19 in patients with autoimmune diseases: survival analysis in a prospective cohort

Authors: Sakir Ahmed, Pankti Mehta, Aby Paul, S Anu, Somy Cherian, Veena Shenoy, Kaveri K Nalianda, Sanjana Joseph, Anagha Poulose, Padmanabha Shenoy

Journal: Ann Rheum Dis

PubMed ID: 35135831

Doi: 10.1136/annrheumdis-2021-221922

Products & Services: Recombinant Proteins

Strategy for Conjugating Oligopeptides to Mesoporous Silica Nanoparticles Using Diazirine-Based Heterobifunctional Linkers

Authors: Md Arif Khan, Ramy W Ghanim, Maelyn R Kiser, Mahsa Moradipour, Dennis T Rogers, John M Littleton, Luke H Bradley, Bert C Lynn, Stephen E Rankin, Barbara L Knutson

Journal: Nanomaterials (Basel)

PubMed ID: 35214937

Doi: 10.3390/nano12040608

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Poor neutralization and rapid decay of antibodies to SARS-CoV-2 variants in vaccinated dialysis patients

Authors: Jessica Bassi, Olivier Giannini, Chiara Silacci-Fregni, Laura Pertusini, Paolo Hitz, Tatiana Terrot, Yves Franzosi, Francesco Muoio, Christian Saliba, Marcel Meury, Exequiel A Dellota, Josh R Dillen, Patrick Hernandez, Nadine Czudnochowski, Elisabetta Cameroni, Nicola Beria, Mariangela Ventresca, Alberto Badellino, Soraya Lavorato-Hadjeres, Elisabetta Lecchi, Tecla Bonora, Matteo Mattiolo, Guido Trinci, Daniela Garzoni, Giuseppe Bonforte, Valentina Forni-Ogna, Davide Giunzioni, Lorenzo Berwert, Ravindra K Gupta, Paolo Ferrari, Alessandro Ceschi, Pietro Cippà, Davide Corti, Antonio Lanzavecchia, Luca Piccoli

Journal: PLoS ONE

PubMed ID: 35143540

Doi: 10.1371/journal.pone.0263328

Products & Services: Recombinant Proteins

Phosphorylation of MdERF17 by MdMPK4 Promotes Apple Fruit Peel Degreening during Light/Dark Transitions

Authors: Shuai Wang, Ting Wang, Qiqi Li, Chen Xu, Ji Tian, Yi Wang, Xinzhong Zhang, Xuefeng Xu, Zhenhai Han, Ting Wu

Journal: Plant Cell

PubMed ID: 35166845

Doi: 10.1093/plcell/koac049

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Microsphere Peptide-Based Immunoassay for the Detection of Recombinant Bovine Somatotropin in Injection Preparations

Authors: Nathalie G E Smits, Toine F H Bovee, Sidharam P Pujari, Leendert A van Ginkel, Michel W F Nielen, Bauke Albada

Journal: Biosensors (Basel)

PubMed ID: 35323408

Doi: 10.3390/bios12030138

Products & Services: Monoclonal Antibody Services

Specific anti-SARS-CoV-2 S1 IgY-scFv is a promising tool for recognition of the virus

Authors: Shikun Ge, Rao Wu, Tingting Zhou, Xiang Liu, Jin Zhu, Xiaoying Zhang

Journal: AMB Express

PubMed ID: 35150368

Doi: 10.1186/s13568-022-01355-4

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A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

Authors: M Gordon Joyce, Hannah A D King, Ines Elakhal-Naouar, Aslaa Ahmed, Kristina K Peachman, Camila Macedo Cincotta, Caroline Subra, Rita E Chen, Paul V Thomas, Wei-Hung Chen, Rajeshwer S Sankhala, Agnes Hajduczki, Elizabeth J Martinez, Caroline E Peterson, William C Chang, Misook Choe, Clayton Smith, Parker J Lee, Jarrett A Headley, Mekdi G Taddese, Hanne A Elyard, Anthony Cook, Alexander Anderson, Kathryn McGuckin Wuertz, Ming Dong, Isabella Swafford, James Brett Case, Jeffrey R Currier, Kerri G Lal, Sebastian Molnar, Manoj S Nair, Vincent Dussupt, Sharon P Daye, Xiankun Zeng, Erica K Barkei, Hilary M Staples, Kendra Alfson, Ricardo Carrion, Shelly J Krebs, Dominic Paquin-Proulx, Nicos Karasavva, Victoria R Polonis, Linda L Jagodzinski, Mihret F Amare, Sandhya Vasan, Paul T Scott, Yaoxing Huang, David D Ho, Natalia de Val, Michael S Diamond, Mark G Lewis, Mangala Rao, Gary R Matyas, Gregory D Gromowski, Sheila A Peel, Nelson L Michael, Diane L Bolton, Kayvon Modjarrad

Journal: Sci Transl Med

PubMed ID: 34914540

Doi: 10.1126/scitranslmed.abi5735

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Pyruvate:ferredoxin oxidoreductase and low abundant ferredoxins support aerobic photomixotrophic growth in cyanobacteria

Authors: Yingying Wang, Xi Chen, Katharina Spengler, Karoline Terberger, Marko Boehm, Jens Appel, Thomas Barske, Stefan Timm, Natalia Battchikova, Martin Hagemann, Kirstin Gutekunst

Journal: Elife

PubMed ID: 35138247

Doi: 10.7554/eLife.71339

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Genome-edited powdery mildew resistance in wheat without growth penalties

Authors: Shengnan Li #, Dexing Lin # , Yunwei Zhang # , Min Deng # , Yongxing Chen , Bin Lv , Boshu Li , Yuan Lei , Yanpeng Wang , Long Zhao , Yueting Liang , Jinxing Liu , Kunling Chen , Zhiyong Liu , Jun Xiao , Jin-Long Qiu , Caixia Gao

Journal: Nature

PubMed ID: 35140403

Doi: 10.1038/s41586-022-04395-9

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Shrimp Plasma MANF Works as an Invertebrate Anti-Inflammatory Factor via a Conserved Receptor Tyrosine Phosphatase

Authors: Kaiwen Luo, Yaohui Chen, Fan Wang

Journal: J Immunol

PubMed ID: 35149533

Doi: 10.4049/jimmunol.2100595

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Effect of gastrointestinal alterations mimicking elderly conditions on in vitro digestion of meat and soy proteins

Authors: Chong Wang, Fan Zhao, Yun Bai, Chunbao Li, Xinglian Xu, Karsten Kristiansen, Guanghong Zhou

Journal: Food chemistry

Doi: 10.1016/j.foodchem.2022.132465

Products & Services: Nucleic Acid Purification & Analysis

p21 restricts influenza A virus by perturbing the viral polymerase complex and upregulating type I interferon signaling

Authors: Chao Ma, Yuhan Li, Yanan Zong, Tony Velkov, Chenxi Wang , Xinyu Yang , Ming Zhang, Zhimin Jiang, Haoran Sun, Qi Tong, Honglei Sun , Juan Pu, Munir Iqbal, Jinhua Liu , Chongshan Dai , Yipeng Sun

Journal: PLoS Pathog

PubMed ID: 35180274

Doi: 10.1371/journal.ppat.1010295

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LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland

Authors: Rongze Ma , Difei Gong , Huanyang You , Chongshen Xu , Yunzhe Lu , Gabriele Bergers , Zena Werb , Ophir D Klein , Claudia K Petritsch , Pengfei Lu

Journal: Cell Rep

PubMed ID: 35172155

Doi: 10.1016/j.celrep.2022.110375

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Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis

Authors: Jingwei Xu, Charles F Ericson, Yun-Wei Lien, Florentine U N Rutaganira, Fabian Eisenstein, Miki Feldmüller, Nicole King, Martin Pilhofer

Journal: Nat Microbiol

PubMed ID: 35165385

Doi: 10.1038/s41564-022-01059-2

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of gluten-degrading prolyl endoprotease from Thermococcus kodakarensis

Authors: Radhakrishna Shetty, Claus Heiner Bang-Berthelsen, Klaudia Weronika Ciurkot, Mike Vestergaard, Per Mårten Hägglund, Harishchandra S Prakash, Timothy John Hobley

Journal: FEMS Microbiol Lett

PubMed ID: 35038331

Doi: 10.1093/femsle/fnac006

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Multilevel interactions between native and ectopic isoprenoid pathways affect global metabolism in rice

Authors: Lucía Pérez, Rui Alves, Laura Perez-Fons, Alfonso Albacete, Gemma Farré, Erika Soto, Ester Vilaprinyó, Cristina Martínez-Andújar, Oriol Basallo, Paul D Fraser, Vicente Medina, Changfu Zhu, Teresa Capell, Paul Christou

Journal: Transgenic Res

PubMed ID: 35201538

Doi: 10.1007/s11248-022-00299-6

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Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

Authors: Mingzhu Yang, Hanwen Yu, Xiu Yu, Shiqi Liang, Yuanlang Hu, Yuxin Luo, Zsuzsanna Izsvák, Chuanbo Sun, Jichang Wang

Journal: Cell Stem Cell

PubMed ID: 35143761

Doi: 10.1016/j.stem.2022.01.010

Products & Services: Proteins, Expression, Isolation and Analysis

Expressing 2-keto acid pathway enzymes significantly increases photosynthetic isobutanol production

Authors: Hao Xie, Peter Lindblad

Journal: Microb Cell Fact

PubMed ID: 35105340

Doi: 10.1186/s12934-022-01738-z

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The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging

Authors: Yilin Ying, Xuefei Hu, Peng Han, Aaron Mendez-Bermudez, Serge Bauwens, Rita Eid, Li Tan, Mélanie Pousse, Marie-Joseph Giraud-Panis, Yiming Lu, Eric Gilson, Jing Ye

Journal: Nucleic Acids Res

PubMed ID: 35150283

Doi: 10.1093/nar/gkac065

Products & Services: Proteins, Expression, Isolation and Analysis

Immune Response of Adult Sickle Cell Disease Patients after COVID-19 Vaccination: The Experience of a Greek Center

Authors: Christos Varelas, Eleni Gavriilaki, Ioanna Sakellari, Philippos Klonizakis, Evaggelia-Evdoxia Koravou, Ioanna Christodoulou, Ioulia Mavrikou, Andreas Kourelis, Fani Chatzopoulou, Dimitrios Chatzidimitriou, Tasoula Touloumenidou, Apostolia Papalexandri, Achilles Anagnostopoulos, Efthimia Vlachaki

Journal: J Clin Med

PubMed ID: 35207208

Doi: 10.3390/jcm11040937

ATPase subunits of the 26S proteasome are important for oocyte maturation in the brown planthopper

Authors: Xu Cheng, Wei Wang, Lu Zhang, Rui-Rui Yang, Ya Ma, Yan-Yuan Bao

Journal: Insect Mol Biol

PubMed ID: 35084067

Doi: 10.1111/imb.12761

Products & Services: Proteins, Expression, Isolation and Analysis

PDE4D targeting enhances anti-tumor effects of sorafenib in clear cell renal cell carcinoma and attenuates MAPK/ERK signaling in a CRAF-dependent manner

Authors: Minghua Cao, Karol Nawalaniec, Amrendra K Ajay, Yueming Luo, Romana Moench, Yanfei Jin, Sheng Xiao, Li-Li Hsiao, Ana Maria Waaga-Gasser

Journal: Transl Oncol