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LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland

Authors: Rongze Ma , Difei Gong , Huanyang You , Chongshen Xu , Yunzhe Lu , Gabriele Bergers , Zena Werb , Ophir D Klein , Claudia K Petritsch , Pengfei Lu

Journal: Cell Rep

PubMed ID: 35172155

Doi: 10.1016/j.celrep.2022.110375

Products & Services: Recombinant Proteins

Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis

Authors: Jingwei Xu, Charles F Ericson, Yun-Wei Lien, Florentine U N Rutaganira, Fabian Eisenstein, Miki Feldmüller, Nicole King, Martin Pilhofer

Journal: Nat Microbiol

PubMed ID: 35165385

Doi: 10.1038/s41564-022-01059-2

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of gluten-degrading prolyl endoprotease from Thermococcus kodakarensis

Authors: Radhakrishna Shetty, Claus Heiner Bang-Berthelsen, Klaudia Weronika Ciurkot, Mike Vestergaard, Per Mårten Hägglund, Harishchandra S Prakash, Timothy John Hobley

Journal: FEMS Microbiol Lett

PubMed ID: 35038331

Doi: 10.1093/femsle/fnac006

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Multilevel interactions between native and ectopic isoprenoid pathways affect global metabolism in rice

Authors: Lucía Pérez, Rui Alves, Laura Perez-Fons, Alfonso Albacete, Gemma Farré, Erika Soto, Ester Vilaprinyó, Cristina Martínez-Andújar, Oriol Basallo, Paul D Fraser, Vicente Medina, Changfu Zhu, Teresa Capell, Paul Christou

Journal: Transgenic Res

PubMed ID: 35201538

Doi: 10.1007/s11248-022-00299-6

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Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

Authors: Mingzhu Yang, Hanwen Yu, Xiu Yu, Shiqi Liang, Yuanlang Hu, Yuxin Luo, Zsuzsanna Izsvák, Chuanbo Sun, Jichang Wang

Journal: Cell Stem Cell

PubMed ID: 35143761

Doi: 10.1016/j.stem.2022.01.010

Products & Services: Proteins, Expression, Isolation and Analysis

Expressing 2-keto acid pathway enzymes significantly increases photosynthetic isobutanol production

Authors: Hao Xie, Peter Lindblad

Journal: Microb Cell Fact

PubMed ID: 35105340

Doi: 10.1186/s12934-022-01738-z

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The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging

Authors: Yilin Ying, Xuefei Hu, Peng Han, Aaron Mendez-Bermudez, Serge Bauwens, Rita Eid, Li Tan, Mélanie Pousse, Marie-Joseph Giraud-Panis, Yiming Lu, Eric Gilson, Jing Ye

Journal: Nucleic Acids Res

PubMed ID: 35150283

Doi: 10.1093/nar/gkac065

Products & Services: Proteins, Expression, Isolation and Analysis

Immune Response of Adult Sickle Cell Disease Patients after COVID-19 Vaccination: The Experience of a Greek Center

Authors: Christos Varelas, Eleni Gavriilaki, Ioanna Sakellari, Philippos Klonizakis, Evaggelia-Evdoxia Koravou, Ioanna Christodoulou, Ioulia Mavrikou, Andreas Kourelis, Fani Chatzopoulou, Dimitrios Chatzidimitriou, Tasoula Touloumenidou, Apostolia Papalexandri, Achilles Anagnostopoulos, Efthimia Vlachaki

Journal: J Clin Med

PubMed ID: 35207208

Doi: 10.3390/jcm11040937

ATPase subunits of the 26S proteasome are important for oocyte maturation in the brown planthopper

Authors: Xu Cheng, Wei Wang, Lu Zhang, Rui-Rui Yang, Ya Ma, Yan-Yuan Bao

Journal: Insect Mol Biol

PubMed ID: 35084067

Doi: 10.1111/imb.12761

Products & Services: Proteins, Expression, Isolation and Analysis

PDE4D targeting enhances anti-tumor effects of sorafenib in clear cell renal cell carcinoma and attenuates MAPK/ERK signaling in a CRAF-dependent manner

Authors: Minghua Cao, Karol Nawalaniec, Amrendra K Ajay, Yueming Luo, Romana Moench, Yanfei Jin, Sheng Xiao, Li-Li Hsiao, Ana Maria Waaga-Gasser

Journal: Transl Oncol

PubMed ID: 35196602

Doi: 10.1016/j.tranon.2022.101377

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The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory human intestinal model

Authors: Benthe van der Lugt, Maartje C P Vos, Mechteld Grootte Bromhaar, Noortje Ijssennagger, Frank Vrieling, Jocelijn Meijerink, Wilma T Steegenga

Journal: Heliyon

PubMed ID: 35169646

Doi: 10.1016/j.heliyon.2022.e08883

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Synthesis and identification of lithocholic acid 3-sulfate as RORγt ligand to inhibit Th17 cell differentiation

Authors: Riping Xiao, Kawai Lei, Hioha Kuok, Wende Deng, Yuxin Zhuang, Yanqing Tang, Zhengyang Guo, Hongyan Qin, Li-Ping Bai, Ting Li

Journal: J Leukoc Biol

PubMed ID: 35188700

Doi: 10.1002/JLB.1MA0122-513R

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Aqueous Extract of Reprogramming Macrophage Polarization by Activating TLR4-NF-κB Signaling Pathway

Authors: Shushu Qian, Xuan Han, Xiaocao Sha, Fang Tian, Hong Huang, Pengjun Jiang, Guoshun Huang, Bangyun Ma, Hong Zhang, Yiye Zhu, Xuemei Sun

Journal: J Inflamm Res

PubMed ID: 35210810

Doi: 10.2147/JIR.S345497

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orter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor

Authors: Chan Zou, Jordan A Beard, Guoping Yang, William E Evans, Erik J Bonten

Journal: J Inflamm Res

PubMed ID: 35221708

Doi: 10.2147/JIR.S333725

Products & Services: Plasmid DNA Preparation

High density lipoprotein nanoparticle as delivery system for radio-sensitising miRNA: An investigation in 2D/3D head and neck cancer models

Authors: Pouya Dehghankelishadi, Michelle F Maritz, Parisa Badiee, Benjamin Thierry

Journal: Int J Pharm

PubMed ID: 35176332

Doi: 10.1016/j.ijpharm.2022.121585

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A machine learning approach-based array sensor for rapidly predicting the mechanisms of action of antibacterial compounds

Authors: Zhijun Li, Kun Jin, Hong Chen, Liyuan Zhang, Guitao Zhang, Yizhou Jiang, Haixia Zou, Wentao Wang, Guangpei Qi, Xiangmeng Qu

Journal: Nanoscale

PubMed ID: 35167631

Doi: 10.1039/d1nr07452k

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The small DdrR protein directly interacts with the UmuDAb regulator of the mutagenic DNA damage response in

Authors: Anja Pavlin, Gregor Bajc, Nadine Fornelos, Douglas F Browning, Matej Butala

Journal: J Bacteriol

PubMed ID: 35191762

Doi: 10.1128/jb.00601-21

Products & Services: ORF cDNA Clones/MolecularCloud

Occludin Promotes Adhesion of CD8 T Cells and Melanocytes in Vitiligo via the HIF-1 Signaling Pathway

Authors: Puyu Zou, Yangfan Xiao, Qiancheng Deng, Yaqian Shi, Ruixuan You, Zixin Pi, Jiani Liu, Yi Zhan, Qinghai Zeng, Zhuotong Zeng, Rong Xiao

Journal: Oxid Med Cell Longev

PubMed ID: 35222802

Doi: 10.1155/2022/6732972

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FXYD domain containing ion transport regulator 5 (FXYD5) silencing promotes cell viability and alleviates inflammatory response in cerulein-induced AR42J cells by blocking JAK2/STAT3 signaling pathway

Authors: Licheng Ding, Jie Li

Journal: Bioengineered

PubMed ID: 35042436

Doi: 10.1080/21655979.2021.2023795

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Occludin Promotes Adhesion of CD8 T Cells and Melanocytes in Vitiligo via the HIF-1 Signaling Pathway

Authors: Puyu Zou, Yangfan Xiao, Qiancheng Deng, Yaqian Shi, Ruixuan You, Zixin Pi, Jiani Liu, Yi Zhan, Qinghai Zeng, Zhuotong Zeng, Rong Xiao

Journal: Oxid Med Cell Longev

PubMed ID: 35222802

Doi: 10.1155/2022/6732972

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The small DdrR protein directly interacts with the UmuDAb regulator of the mutagenic DNA damage response in

Authors: Anja Pavlin, Gregor Bajc, Nadine Fornelos, Douglas F Browning, Matej Butala

Journal: J Bacteriol

PubMed ID: 35191762

Doi: 10.1128/jb.00601-21

Products & Services: ORF cDNA Clones/MolecularCloud

Identification and Characterization of a Set of Monocot BAHD Monolignol Transferases

Authors: Rebecca A Smith, Emily T Beebe, Craig A Bingman, Kirk Vander Meulen, Alexis Eugene, Alexander J Steiner, Steven D Karlen, John Ralph, Brian G Fox

Journal: Plant Physiol

PubMed ID: 35134228

Doi: 10.1093/plphys/kiac035

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Identification and Characterization of a Set of Monocot BAHD Monolignol Transferases

Authors: Rebecca A Smith, Emily T Beebe, Craig A Bingman, Kirk Vander Meulen, Alexis Eugene, Alexander J Steiner, Steven D Karlen, John Ralph, Brian G Fox

Journal: Plant Physiol

PubMed ID: 35134228

Doi: 10.1093/plphys/kiac035

Products & Services: Plasmid DNA Preparation

Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy

Authors: Flavia Rodrigues Oliveira Silva, Nelson Batista Lima, Maria Helena Bellini, Luiz Felipe Silva Teixeira, Eric Yiwei Du, Niloufar Jamshidi, Justin Gooding, Adam David Martin, Alexander Macmillan, Christopher Peter Marquis, Pall Thordarson

Journal: Nanotheranostics

PubMed ID: 35223382

Doi: 10.7150/ntno.68789

Products & Services: Mammalian Expression

Rapid screening of aptamers for fluorescent targets by integrated digital PCR and flow cytometry

Authors: Xiaona Fang, Wenjing Li, Tian Gao, Qurat Ul Ain Zahra, Zhaofeng Luo, Renjun Pei

Journal: Talanta

PubMed ID: 35180537

Doi: 10.1016/j.talanta.2022.123302

Products & Services: Custom DNA/RNA Oligos

Transformation of by for the Expression of the Hemagglutinin of Avian Influenza Virus H5

Authors: Inkar Castellanos-Huerta, Gabriela Gómez-Verduzco, Guillermo Tellez-Isaias, Guadalupe Ayora-Talavera, Bernardo Bañuelos-Hernández, Víctor Manuel Petrone-García, Gilberto Velázquez-Juárez, Isidro Fernández-Siurob

Journal: Microorganisms

PubMed ID: 35208815

Doi: 10.3390/microorganisms10020361

Products & Services: Codon Optimization

The Anticancer Effect of a Conjugated Antimicrobial Peptide Against Colorectal Cancer (CRC) Cells

Authors: Raed Obaid Saleh, Ihsan Naji Atiyah Essia, Saade Abdalkareem Jasim

Journal: J Gastrointest Cancer

PubMed ID: 35217999

Doi: 10.1007/s12029-021-00799-4

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Aluminum nanoparticles deliver a dual-epitope peptide for enhanced anti-tumor immunotherapy

Authors: Shuting Bai, Hao Jiang, Yuanshuai Song, Yining Zhu, Ming Qin, Chunting He, Guangsheng Du, Xun Sun

Journal: J Control Release

PubMed ID: 35217098

Doi: 10.1016/j.jconrel.2022.02.027

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A self-assembling nanoparticle vaccine targeting the conserved epitope of influenza virus hemagglutinin stem elicits a cross-protective immune response

Authors: Yongbo Qiao, Shuang Li, Shenghui Jin, Yi Pan, Yuhua Shi, Wei Kong, Yaming Shan

Journal: Nanoscale

PubMed ID: 35157751

Doi: 10.1039/d1nr08460g

Products & Services: Plasmid DNA Preparation

A Novel CD3/BCMA Bispecific T-cell Redirecting Antibody for the Treatment of Multiple Myeloma

Authors: Mengshang Xiong, Ruoqi Liu, Xiaomin Lei, Dongmei Fan, Fangzhen Lin, Wei Hao, Xiangfei Yuan, Yuanyuan Yang, Xiaolong Zhang, Zhou Ye, Yang Lu, Yanjun Zhang, Jianxiang Wang, Dongsheng Xiong

Journal: J Immunother

PubMed ID: 34711791

Doi: 10.1097/CJI.0000000000000401

Products & Services: Proteins, Expression, Isolation and Analysis

Ligand-directed bias of G protein signaling at the dopamine D2 receptor

Authors: Ee Von Moo , Kasper Harpsøe , Alexander S Hauser , Ikuo Masuho , Hans Bräuner-Osborne , David E Gloriam , Kirill A Martemyanov

Journal: Cell Chem Biol .

PubMed ID: 34302750

Doi: 10.1016/j.chembiol.2021.07.004

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and evaluation of imatinib as an inhibitor for SARS-CoV-2

Authors: Nirmitee Mulgaonkar, Haoqi Wang, Samavath Mallawarachchi, Daniel Růžek, Byron Martina, Sandun Fernando

Journal: J Biomol Struct Dyn

PubMed ID: 35220926

Doi: 10.1080/07391102.2022.2045221

Products & Services: Mammalian Expression

Long noncoding RNA ADIRF antisense RNA 1 upregulates insulin receptor substrate 1 to decrease the aggressiveness of osteosarcoma by sponging microRNA-761

Authors: Lingling Xu, Yinling Tan, Fengxia Xu, Yong Zhang

Journal: Bioengineered

PubMed ID: 35030964

Doi: 10.1080/21655979.2021.2019872

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membrane vesicles cause endothelial barrier failure and lung injury

Authors: Mark J McVey, Mazharul Maishan, Anna Foley, Razan Turki, Elyse J Roach, Rose Deschler, Sarah Weidenfeld, Neil M Goldenberg, Cezar M Khursigara, Wolfgang M Kuebler

Journal: Eur Respir J

PubMed ID: 35169027

Doi: 10.1183/13993003.01500-2021

Products & Services: ORF cDNA Clones/MolecularCloud

Vaccination Strategies at a COVID-19 Mass Vaccination Site

Authors: Sheng-Huang Hsiao, Sheng-Jean Huang, Chiao-Yu Huang

Journal: Int J Health Policy Manag

PubMed ID: 35247942

Doi: 10.34172/ijhpm.2022.6881

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Base excision repair system targeting DNA adducts of trioxacarcin/LL-D49194 antibiotics for self-resistance

Authors: Xiaorong Chen, Noah P Bradley, Wei Lu, Katherine L Wahl, Mei Zhang, Hua Yuan, Xian-Feng Hou, Brandt F Eichman, Gong-Li Tang

Journal: Nucleic Acids Res

PubMed ID: 35191495

Doi: 10.1093/nar/gkac085

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NR3C2 suppresses the proliferation, migration, invasion and angiogenesis of colon cancer cells by inhibiting the AKT/ERK signaling pathway

Authors: Jia Li, Zhao Xu

Journal: Mol Med Rep

PubMed ID: 35191517

Doi: 10.3892/mmr.2022.12649

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OmpA may be used as a novel target to enrich and detect Escherichia coli in milk samples

Authors: Yichen Tian, Kaiqing Yang, Yaoqiang Shi, Jinyang Zhang, Qinqin Han, Xueshan Xia, Yuzhu Song

Journal: J Dairy Sci

PubMed ID: 35151480

Doi: 10.3168/jds.2021-20974

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An insect antifreeze protein from Anatolica polita enhances the cryoprotection of Xenopus laevis eggs and embryos

Authors: Predrag Jevtić, K Wade Elliott, Shelby E Watkins, Jonathan A Sreter, Katarina Jovic, Ian B Lehner, Paul W Baures, John G Tsavalas, Daniel L Levy, Krisztina Varga

Journal: J Exp Biol

PubMed ID: 35014670

Doi: 10.1242/jeb.243662

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Crystal packing reveals rapamycin-mediated homodimerization of an FK506-binding domain

Authors: Ajit Kumar Singh, Ketul Saharan, Somanath Baral, Sheng Luan, Dileep Vasudevan

Journal: Int J Biol Macromol

PubMed ID: 35218805

Doi: 10.1016/j.ijbiomac.2022.02.107

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Backbone NMR resonance assignment of the intrinsically disordered UBact protein from Nitrospira nitrosa

Authors: Steven M Bonn, David Fushman

Journal: Biomol NMR Assign

PubMed ID: 35107780

Doi: 10.1007/s12104-022-10070-x

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Development and validation of an LC-MS/MS based quantitative assay for marmoset insulin in serum

Authors: Robinson W Goy, Hemanta K Shrestha, Ricki J Colman, Natalie J Dukes, Toni E Ziegler, Amita Kapoor

Journal: J Chromatogr B Analyt Technol Biomed Life Sci

PubMed ID: 35247678

Doi: 10.1016/j.jchromb.2022.123150

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Development and validation of an LC-MS/MS based quantitative assay for marmoset insulin in serum

Authors: Robinson W Goy, Hemanta K Shrestha, Ricki J Colman, Natalie J Dukes, Toni E Ziegler, Amita Kapoor

Journal: J Chromatogr B Analyt Technol Biomed Life Sci

PubMed ID: 35247678

Doi: 10.1016/j.jchromb.2022.123150

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Distinct impact of DMARD combination and monotherapy in immunogenicity of an inactivated SARS-CoV-2 vaccine in rheumatoid arthritis

Authors: Ana Cristina Medeiros-Ribeiro, Karina Rossi Bonfiglioli, Diogo Souza Domiciano, Andrea Yukie Shimabuco, Henrique Carriço da Silva, Carla G S Saad, Emily Figueiredo Neves Yuki, Sandra Gofinet Pasoto, Carlo Scognamiglio Renner Araujo, Tatiane Lie Nakai, Clóvis Artur Silva, Tatiana Pedrosa, Léonard de Vinci Kanda Kupa, Matheus Santos Rodrigues Silva, Guilherme Guimarães Moreira Balbi, Esper Georges Kallas, Nádia Emi Aikawa, Eloisa Bonfa

Journal: Ann Rheum Dis

PubMed ID: 35135832

Doi: 10.1136/annrheumdis-2021-221735

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Microparticles from Hyperphosphatemia-Stimulated Endothelial Cells Promote Vascular Calcification Through Astrocyte-Elevated Gene-1

Authors: Yazhou Xiang, Yingjie Duan, Zhong Peng, Hong Huang, Wenjun Ding, En Chen, Zilong Liu, Chengyun Dou, Jianlong Li, Jihong Ou, Qingsong Wan, Bo Yang, Zhangxiu He

Journal: Calcif Tissue Int

PubMed ID: 35195734

Doi: 10.1007/s00223-022-00960-6

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Physiological ROS controls Upd3-dependent modeling of ECM to support cardiac function in

Authors: Jayati Gera, Prerna Budakoti, Meghna Suhag, Lolitika Mandal, Sudip Mandal

Journal: Sci Adv

PubMed ID: 35179958

Doi: 10.1126/sciadv.abj4991

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Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

Authors: Chi-Chuan Lin, Kin Man Suen, Polly-Anne Jeffrey, Lukasz Wieteska, Jessica A Lidster, Peng Bao, Alistair P Curd, Amy Stainthorp, Caroline Seiler, Hans Koss, Eric Miska, Zamal Ahmed, Stephen D Evans, Carmen Molina-París, John E Ladbury

Journal: Mol Cell

PubMed ID: 35231400

Doi: 10.1016/j.molcel.2022.02.005

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CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity

Authors: Yiru Long , Jianhua Sun , Tian-Zhang Song , Tingting Liu , Feng Tang , Xinxin Zhang, Longfei Ding , Yunqiu Miao , Weiliang Zhu , Xiaoyan Pan , Qi An, Mian Qin , Xiankun Tong , Xionghua Peng , Pan Yu, Peng Zhu , Jianqing Xu , Xiaoyan Zhang , Yachun Zhang , Datao Liu, Ben Chen , Huilin Chen , Leike Zhang , Gengfu Xiao, Jianping Zuo , Wei Tang , Ji Zhou, Heng Li , Zhijian Xu, Hong-Yi Zheng , Xin-Yan Long , Qiuping Qin , Yong Gan , Jin Ren , Wei Huang , Yong-Tang Zheng , Guangyi Jin , Likun Gong

Journal: Cell Discov .

PubMed ID: 35102138

Doi: 10.1038/s41421-021-00370-2

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Development of SARS-CoV-2 variant protein microarray for profiling humoral immunity in vaccinated subjects

Authors: Tzong-Shiann Ho, Pin-Xian Du, Wen-Yu Su, Harvey M Santos, Ya-Lan Lin, Yi-Yu Chou, Batuhan Birol Keskin, Chi Ho Pau, Guan-Da Syu

Journal: Biosens Bioelectron

PubMed ID: 35168024

Doi: 10.1016/j.bios.2022.114067

CoronaVac and ChAdOx1 Vaccination and Gamma Infection Elicited Neutralizing Antibodies against the SARS-CoV-2 Delta Variant

Authors: Marcilio Jorge Fumagalli, Luiza Antunes Castro-Jorge, William Marciel de Souza, Patrick Orestes de Azevedo, Alana Witt Hansen, Ricardo Tostes Gazzinelli, Benedito Antônio Lopes da Fonseca, Fernando Rosado Spilki, Luiz Tadeu Moraes Figueiredo

Journal: Viruses

PubMed ID: 35215895

Doi: 10.3390/v14020305

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