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Silencing of IGF2BP1 restrains ox-LDL-induced lipid accumulation and inflammation by reducing RUNX1 expression and promoting autophagy in macrophages

Authors: Mingxin Liu, Guizhou Tao, Yiming Cao, Yu Hu, Zhe Zhang

Journal: J Biochem Mol Toxicol

PubMed ID: 35179253

Doi: 10.1002/jbt.22994

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Development of a Test Card Based on Colloidal Gold Immunochromatographic Strips for Rapid Detection of Antibodies against Theileria equi and Babesia caballi

Authors: Guangpu Yang, Kewei Chen, Wei Guo, Zhe Hu, Ting Qi, Diqiu Liu, Yaoxin Wang, Cheng Du, Xiaojun Wang

Journal: Microbiol Spectr

PubMed ID: 35196786

Doi: 10.1128/spectrum.02411-21

Products & Services: Proteins, Expression, Isolation and Analysis

Genome-wide identification and characterization of aquaporins in mangrove plant Kandelia obovata and its role in response to the intertidal environment

Authors: Zejun Guo, Dongna Ma, Jing Li, Mingyue Wei, Ludan Zhang, Lichun Zhou, Xiaoxuan Zhou, Shanshan He, Lin Wang, Yingjia Shen, Qingshun Quinn Li, Hai-Lei Zheng

Journal: Plant Cell Environ

PubMed ID: 35141923

Doi: 10.1111/pce.14286

Products & Services: Protein Tools

Cytolysin A-mediated protein exportation efficiency and its role in enhancing the fitness of live recombinant Salmonella Typhi vaccine strain

Authors: F-K Loh, S Nathan, S-C Chow, C-M Fang

Journal: Lett Appl Microbiol

PubMed ID: 35138654

Doi: 10.1111/lam.13669

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Distinct Homologous and Variant-Specific Memory B-Cell and Antibody Response Over Time after SARS-CoV-2 mRNA Vaccination

Authors: Iana H Haralambieva, Jonathon M Monroe, Inna G Ovsyannikova, Diane E Grill, Gregory A Poland, Richard B Kennedy

Journal: J Infect Dis

PubMed ID: 35137144

Doi: 10.1093/infdis/jiac042

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Distinct Homologous and Variant-Specific Memory B-Cell and Antibody Response Over Time after SARS-CoV-2 mRNA Vaccination

Authors: Iana H Haralambieva, Jonathon M Monroe, Inna G Ovsyannikova, Diane E Grill, Gregory A Poland, Richard B Kennedy

Journal: J Infect Dis

PubMed ID: 35137144

Doi: 10.1093/infdis/jiac042

Products & Services: Recombinant Proteins

Ultrasensitive Label-Free DNA Detection Based on Solution-Gated Graphene Transistors Functionalized with Carbon Quantum Dots

Authors: Minghua Deng, Jinhua Li, Bichen Xiao, Zhanpeng Ren, Ziqin Li, Haiyang Yu, Jiashen Li, Jianying Wang, Zhaowei Chen, Xianbao Wang

Journal: Anal Chem

PubMed ID: 35147418

Doi: 10.1021/acs.analchem.1c05309

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Biochemical Screening of Potent Zika Virus Protease Inhibitors

Authors: Camila Coelho, Gloria Gallo, Leon Hardy, Maria Elena Bottazzi, Claudia Campos, Martin Würtele

Journal: ChemMedChem

PubMed ID: 35104396

Doi: 10.1002/cmdc.202100695

Products & Services: Proteins, Expression, Isolation and Analysis

TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer

Authors: Chanju Lee, Soyoung Kim, Chanmi Jeong, Inhee Cho, Juyeon Jo, Ik-Hwan Han, Hyunsu Bae

Journal: Int J Mol Sci

PubMed ID: 35216272

Doi: 10.3390/ijms23042157

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Enzymatic activity of glycosyltransferase GLT8D1 promotes human glioblastoma cell migration

Authors: Elena I Ilina, Camille Cialini, Dietlind L Gerloff, Maitane Duarte Garcia-Escudero, Céline Jeanty, Marie-Laëtitia Thézénas, Antoine Lesur, Vincent Puard, François Bernardin, Alina Moter, Anne Schuster, Monika Dieterle, Anna Golebiewska, Jean-Jacques Gérardy, Gunnar Dittmar, Simone P Niclou, Tanja Müller, Michel Mittelbronn

Journal: iScience

PubMed ID: 35198895

Doi: 10.1016/j.isci.2022.103842

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Enrofloxacin Promotes Plasmid-Mediated Conjugation Transfer of Fluoroquinolone-Resistance Gene

Authors: Yue Zhao, Zhengzheng Cao, Luqing Cui, Tianyu Hu, Kaixuan Guo, Fan Zhang, Xiangru Wang, Zhong Peng, Quan Liu, Menghong Dai

Journal: Front Microbiol

PubMed ID: 35250901

Doi: 10.3389/fmicb.2021.773664

Products & Services: Proteins, Expression, Isolation and Analysis

A Novel TRIM9 Protein Promotes NF-κB Activation Through Interacting With LvIMD in Shrimp During WSSV Infection

Authors: Mingzhe Sun, Shihao Li, Songjun Jin, Xuechun Li, Jianhai Xiang, Fuhua Li

Journal: Front Immunol

PubMed ID: 35281067

Doi: 10.3389/fimmu.2022.819881

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular basis of receptor binding and antibody neutralization of Omicron

Authors: Qin Hong, Wenyu Han, Jiawei Li, Shiqi Xu, Yifan Wang, Cong Xu, Zuyang Li, Yanxing Wang, Chao Zhang, Zhong Huang, Yao Cong

Journal: Nature

PubMed ID: 35228716

Doi: 10.1038/s41586-022-04581-9

Products & Services: Mammalian Expression

Far-Red Light Triggered Production of Bispecific T Cell Engagers (BiTEs) from Engineered Cells for Antitumor Application

Authors: Cuilin Zhang, Yingjun Shi, Lingjie Wu, Chenyi Wang, Naishun Liao, Fei Wang, Bixing Zhao, Yingchao Wang, Xiaolong Liu

Journal: ACS Synth Biol

PubMed ID: 35113526

Doi: 10.1021/acssynbio.1c00523

Products & Services: Proteins, Expression, Isolation and Analysis

From In Vitro Data to In Vivo Interspecies Danger Communication: A Study of Chemosensing via the Mouse Grueneberg Ganglion

Authors: Ana Catarina Lopes, Julien Brechbühl, Flavio Ferreira, Marjorie Amez-Droz, Marie-Christine Broillet

Journal: Animals (Basel)

PubMed ID: 35158677

Doi: 10.3390/ani12030356

Products & Services: Mammalian Expression

Rapid, Visual, and Sequence-Specific Detection of in Egg Liquid with vis-NEAA, a CRISPR/Cas12 Empowered New Strategy

Authors: Linlin Bai, Liu Wang, Shuqin Huang, Rong Bai, Xucong Lv, Liping Sun, Fang Zhang, Xiahong Xu

Journal: J Agric Food Chem

PubMed ID: 35138842

Doi: 10.1021/acs.jafc.1c06715

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Longitudinal analysis of antibody dynamics in COVID-19 convalescents reveals neutralizing responses up to 16 months after infection

Authors: Yang Yang, Minghui Yang, Yun Peng, Yanhua Liang, Jinli Wei, Li Xing, Liping Guo, Xiaohe Li, Jie Li, Jun Wang, Mianhuan Li, Zhixiang Xu, Mingxia Zhang, Fuxiang Wang, Yi Shi, Jing Yuan, Yingxia Liu

Journal: Nat Microbiol

PubMed ID: 35132197

Doi: 10.1038/s41564-021-01051-2

Products & Services: Gene Synthesis

encoding GDP-D-mannose pyrophosphorylase from celery enhanced the accumulation of ascorbic acid and resistance to drought stress in

Authors: Yan-Hua Liu, Hao Wang, Jie-Xia Liu, Sheng Shu, Guo-Fei Tan, Meng-Yao Li, Ao-Qi Duan, Hui Liu, Ai-Sheng Xiong

Journal: PeerJ

PubMed ID: 35233296

Doi: 10.7717/peerj.12976

Products & Services: Recombinant Proteins

encoding GDP-D-mannose pyrophosphorylase from celery enhanced the accumulation of ascorbic acid and resistance to drought stress in

Authors: Yan-Hua Liu, Hao Wang, Jie-Xia Liu, Sheng Shu, Guo-Fei Tan, Meng-Yao Li, Ao-Qi Duan, Hui Liu, Ai-Sheng Xiong

Journal: PeerJ

PubMed ID: 35233296

Doi: 10.7717/peerj.12976

Products & Services: Recombinant Proteins

Challenges of expressing recombinant human tissue factor as a secreted protein in

Authors: Mohammad Jalili-Nik, Mohammad Soukhtanloo, Majid Mojarrad, Mohammad Hadi Sadeghian, Baratali Mashkani

Journal: Prep Biochem Biotechnol

PubMed ID: 35133942

Doi: 10.1080/10826068.2021.2023823

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Higher SARS-CoV-2 Spike Binding Antibody Levels and Neutralization Capacity 6 Months after Heterologous Vaccination with AZD1222 and BNT162b2

Authors: Brigitte Müller-Hilke, Franz Mai, Michael Müller, Johann Volzke, Emil C Reisinger

Journal: Vaccines (Basel)

PubMed ID: 35214780

Doi: 10.3390/vaccines10020322

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A broad-spectrum nanobody targeting the C-terminus of the hepatitis B surface antigen for chronic hepatitis B infection therapy

Authors: Yue Wang, Yaxian Mei, Zhenghong Ao, Yuanzhi Chen, Yichao Jiang, Xiaoqing Chen, Ruoyao Qi, Baorong Fu, Jixian Tang, Mujin Fang, Min You, Tianying Zhang, Quan Yuan, Wenxin Luo, Ningshao Xia

Journal: Antiviral Res

PubMed ID: 35183645

Doi: 10.1016/j.antiviral.2022.105265

Products & Services: Proteins, Expression, Isolation and Analysis

Metal Dependence and Functional Diversity of Type I Cas3 Nucleases

Authors: Sining Sun, Zunyu He, Paul Jiang, Rishika Baral, Maria-Eirini Pandelia

Journal: Biochemistry

PubMed ID: 35184547

Doi: 10.1021/acs.biochem.1c00779

Products & Services: Codon Optimization

Impact of the clinically approved Petasites hybridus extract Ze 339 on intestinal mechanisms involved in the handling of histamine

Authors: Lina G Mettler, Karin Brecht, Veronika Butterweck, Henriette E Meyer Zu Schwabedissen

Journal: Biomed Pharmacother

PubMed ID: 35149385

Doi: 10.1016/j.biopha.2022.112698

Products & Services: Proteins, Expression, Isolation and Analysis

Calcium and integrin-binding protein 1-like interacting with an integrin α-cytoplasmic domain facilitates cellular immunity in Helicoverpa armigera

Authors: Ming-Ming Zhang, Ling-Ling Luo, Yu Liu, Gui-Jie Wang, Huan-Huan Zheng, Xu-Sheng Liu, Jia-Lin Wang

Journal: Dev Comp Immunol

PubMed ID: 35231466

Doi: 10.1016/j.dci.2022.104379

Products & Services: Recombinant Antibody Expression

Aluminum nanoparticles deliver a dual-epitope peptide for enhanced anti-tumor immunotherapy

Authors: Shuting Bai, Hao Jiang, Yuanshuai Song, Yining Zhu, Ming Qin, Chunting He, Guangsheng Du, Xun Sun

Journal: J Control Release

PubMed ID: 35217098

Doi: 10.1016/j.jconrel.2022.02.027

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Comparison of Neutralizing Antibody Responses at 6 Months Post Vaccination with BNT162b2 and AZD1222

Authors: Evangelos Terpos, Vangelis Karalis, Ioannis Ntanasis-Stathopoulos, Zoi Evangelakou, Maria Gavriatopoulou, Maria S Manola, Panagiotis Malandrakis, Despoina D Gianniou, Efstathios Kastritis, Ioannis P Trougakos, Meletios A Dimopoulos

Journal: Biomedicines

PubMed ID: 35203547

Doi: 10.3390/biomedicines10020338

The Outer Membrane Lipoprotein Tp0136 Stimulates Human Platelet Activation and Aggregation Through PAR1 to Enhance G/G Signaling

Authors: Qiu-Yan Xu, Yong-Jing Wang, Li-Rong Lin, Li-Li Liu, Tian-Ci Yang

Journal: Front Immunol

PubMed ID: 35296084

Doi: 10.3389/fimmu.2022.818151

Products & Services: Proteins, Expression, Isolation and Analysis

The Secreted Protein PA3611 Promotes Bronchial Epithelial Cell Epithelial-Mesenchymal Transition via Integrin αvβ6-Mediated TGF-β1-Induced p38/NF-κB Pathway Activation

Authors: Lei Shu, Sixia Chen, Shaoqing Lin, Huan Lin, Yan Shao, Jing Yao, Lili Qu, Yunshi Zhang, Xing Liu, Xingran Du, Kaili Deng, Xiaolin Chen, Ganzhu Feng

Journal: Front Microbiol

PubMed ID: 35197937

Doi: 10.3389/fmicb.2021.763749

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Vasoactive Intestinal Peptide Indirectly Elicits Pituitary LH Secretion Independent of GnRH in Female Zebrafish

Authors: Sakura Tanaka, Nilli Zmora, Berta Levavi-Sivan, Yonathan Zohar

Journal: Endocrinology

PubMed ID: 34978328

Doi: 10.1210/endocr/bqab264

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Multilevel interactions between native and ectopic isoprenoid pathways affect global metabolism in rice

Authors: Lucía Pérez, Rui Alves, Laura Perez-Fons, Alfonso Albacete, Gemma Farré, Erika Soto, Ester Vilaprinyó, Cristina Martínez-Andújar, Oriol Basallo, Paul D Fraser, Vicente Medina, Changfu Zhu, Teresa Capell, Paul Christou

Journal: Transgenic Res

PubMed ID: 35201538

Doi: 10.1007/s11248-022-00299-6

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The non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging

Authors: Yilin Ying, Xuefei Hu, Peng Han, Aaron Mendez-Bermudez, Serge Bauwens, Rita Eid, Li Tan, Mélanie Pousse, Marie-Joseph Giraud-Panis, Yiming Lu, Eric Gilson, Jing Ye

Journal: Nucleic Acids Res

PubMed ID: 35150283

Doi: 10.1093/nar/gkac065

Products & Services: Proteins, Expression, Isolation and Analysis

Immune Response of Adult Sickle Cell Disease Patients after COVID-19 Vaccination: The Experience of a Greek Center

Authors: Christos Varelas, Eleni Gavriilaki, Ioanna Sakellari, Philippos Klonizakis, Evaggelia-Evdoxia Koravou, Ioanna Christodoulou, Ioulia Mavrikou, Andreas Kourelis, Fani Chatzopoulou, Dimitrios Chatzidimitriou, Tasoula Touloumenidou, Apostolia Papalexandri, Achilles Anagnostopoulos, Efthimia Vlachaki

Journal: J Clin Med

PubMed ID: 35207208

Doi: 10.3390/jcm11040937

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

Authors: M Gordon Joyce, Hannah A D King, Ines Elakhal-Naouar, Aslaa Ahmed, Kristina K Peachman, Camila Macedo Cincotta, Caroline Subra, Rita E Chen, Paul V Thomas, Wei-Hung Chen, Rajeshwer S Sankhala, Agnes Hajduczki, Elizabeth J Martinez, Caroline E Peterson, William C Chang, Misook Choe, Clayton Smith, Parker J Lee, Jarrett A Headley, Mekdi G Taddese, Hanne A Elyard, Anthony Cook, Alexander Anderson, Kathryn McGuckin Wuertz, Ming Dong, Isabella Swafford, James Brett Case, Jeffrey R Currier, Kerri G Lal, Sebastian Molnar, Manoj S Nair, Vincent Dussupt, Sharon P Daye, Xiankun Zeng, Erica K Barkei, Hilary M Staples, Kendra Alfson, Ricardo Carrion, Shelly J Krebs, Dominic Paquin-Proulx, Nicos Karasavva, Victoria R Polonis, Linda L Jagodzinski, Mihret F Amare, Sandhya Vasan, Paul T Scott, Yaoxing Huang, David D Ho, Natalia de Val, Michael S Diamond, Mark G Lewis, Mangala Rao, Gary R Matyas, Gregory D Gromowski, Sheila A Peel, Nelson L Michael, Diane L Bolton, Kayvon Modjarrad

Journal: Sci Transl Med

PubMed ID: 34914540

Doi: 10.1126/scitranslmed.abi5735

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Pyruvate:ferredoxin oxidoreductase and low abundant ferredoxins support aerobic photomixotrophic growth in cyanobacteria

Authors: Yingying Wang, Xi Chen, Katharina Spengler, Karoline Terberger, Marko Boehm, Jens Appel, Thomas Barske, Stefan Timm, Natalia Battchikova, Martin Hagemann, Kirstin Gutekunst

Journal: Elife

PubMed ID: 35138247

Doi: 10.7554/eLife.71339

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Antibody-Drug Conjugate Targeting c-Kit for the Treatment of Small Cell Lung Cancer

Authors: Kwang-Hyeok Kim, Jin-Ock Kim, Jeong-Yang Park, Min-Duk Seo, Sang Gyu Park

Journal: Int J Mol Sci

PubMed ID: 35216379

Doi: 10.3390/ijms23042264

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Characterization of gluten-degrading prolyl endoprotease from Thermococcus kodakarensis

Authors: Radhakrishna Shetty, Claus Heiner Bang-Berthelsen, Klaudia Weronika Ciurkot, Mike Vestergaard, Per Mårten Hägglund, Harishchandra S Prakash, Timothy John Hobley

Journal: FEMS Microbiol Lett

PubMed ID: 35038331

Doi: 10.1093/femsle/fnac006

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A truncated CC-NB-ARC gene TaRPP13L1-3D positively regulates powdery mildew resistance in wheat via the RanGAP-WPP complex-mediated nucleocytoplasmic shuttle

Authors: Xiangyu Zhang, Guanghao Wang, Xiaojian Qu, Mengmeng Wang, Huan Guo, Lu Zhang, Tingdong Li, Yajuan Wang, Hong Zhang, Wanquan Ji

Journal: Planta

PubMed ID: 35133503

Doi: 10.1007/s00425-022-03843-0

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Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis

Authors: Ya Yang, Yanfei Chen, Yalei Zhao, Feiyang Ji, Lingjian Zhang, Shima Tang, Sainan Zhang, Qingqing Hu, Zuhong Li, Fen Zhang, Qian Li, Lanjuan Li

Journal: Stem Cell Res Ther

PubMed ID: 35123555

Doi: 10.1186/s13287-022-02734-1

Products & Services: Proteins, Expression, Isolation and Analysis

Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis

Authors: Jingwei Xu, Charles F Ericson, Yun-Wei Lien, Florentine U N Rutaganira, Fabian Eisenstein, Miki Feldmüller, Nicole King, Martin Pilhofer

Journal: Nat Microbiol

PubMed ID: 35165385

Doi: 10.1038/s41564-022-01059-2

Products & Services: Proteins, Expression, Isolation and Analysis

Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

Authors: Mingzhu Yang, Hanwen Yu, Xiu Yu, Shiqi Liang, Yuanlang Hu, Yuxin Luo, Zsuzsanna Izsvák, Chuanbo Sun, Jichang Wang

Journal: Cell Stem Cell

PubMed ID: 35143761

Doi: 10.1016/j.stem.2022.01.010

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Expressing 2-keto acid pathway enzymes significantly increases photosynthetic isobutanol production

Authors: Hao Xie, Peter Lindblad

Journal: Microb Cell Fact

PubMed ID: 35105340

Doi: 10.1186/s12934-022-01738-z

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ATPase subunits of the 26S proteasome are important for oocyte maturation in the brown planthopper

Authors: Xu Cheng, Wei Wang, Lu Zhang, Rui-Rui Yang, Ya Ma, Yan-Yuan Bao

Journal: Insect Mol Biol

PubMed ID: 35084067

Doi: 10.1111/imb.12761

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Nuclear morphogenesis: forming a heterogeneous nucleus during embryogenesis

Authors: Albert Tsai, Justin Crocker

Journal: Development

PubMed ID: 35142344

Doi: 10.1242/dev.200266

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Microsphere Peptide-Based Immunoassay for the Detection of Recombinant Bovine Somatotropin in Injection Preparations

Authors: Nathalie G E Smits, Toine F H Bovee, Sidharam P Pujari, Leendert A van Ginkel, Michel W F Nielen, Bauke Albada

Journal: Biosensors (Basel)

PubMed ID: 35323408

Doi: 10.3390/bios12030138

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The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory human intestinal model

Authors: Benthe van der Lugt, Maartje C P Vos, Mechteld Grootte Bromhaar, Noortje Ijssennagger, Frank Vrieling, Jocelijn Meijerink, Wilma T Steegenga

Journal: Heliyon

PubMed ID: 35169646

Doi: 10.1016/j.heliyon.2022.e08883

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Strategy for Conjugating Oligopeptides to Mesoporous Silica Nanoparticles Using Diazirine-Based Heterobifunctional Linkers

Authors: Md Arif Khan, Ramy W Ghanim, Maelyn R Kiser, Mahsa Moradipour, Dennis T Rogers, John M Littleton, Luke H Bradley, Bert C Lynn, Stephen E Rankin, Barbara L Knutson

Journal: Nanomaterials (Basel)

PubMed ID: 35214937

Doi: 10.3390/nano12040608

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Poor neutralization and rapid decay of antibodies to SARS-CoV-2 variants in vaccinated dialysis patients

Authors: Jessica Bassi, Olivier Giannini, Chiara Silacci-Fregni, Laura Pertusini, Paolo Hitz, Tatiana Terrot, Yves Franzosi, Francesco Muoio, Christian Saliba, Marcel Meury, Exequiel A Dellota, Josh R Dillen, Patrick Hernandez, Nadine Czudnochowski, Elisabetta Cameroni, Nicola Beria, Mariangela Ventresca, Alberto Badellino, Soraya Lavorato-Hadjeres, Elisabetta Lecchi, Tecla Bonora, Matteo Mattiolo, Guido Trinci, Daniela Garzoni, Giuseppe Bonforte, Valentina Forni-Ogna, Davide Giunzioni, Lorenzo Berwert, Ravindra K Gupta, Paolo Ferrari, Alessandro Ceschi, Pietro Cippà, Davide Corti, Antonio Lanzavecchia, Luca Piccoli

Journal: PLoS ONE

PubMed ID: 35143540

Doi: 10.1371/journal.pone.0263328

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Phosphorylation of MdERF17 by MdMPK4 Promotes Apple Fruit Peel Degreening during Light/Dark Transitions

Authors: Shuai Wang, Ting Wang, Qiqi Li, Chen Xu, Ji Tian, Yi Wang, Xinzhong Zhang, Xuefeng Xu, Zhenhai Han, Ting Wu

Journal: Plant Cell

PubMed ID: 35166845

Doi: 10.1093/plcell/koac049

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Postvaccination antibody titres predict protection against COVID-19 in patients with autoimmune diseases: survival analysis in a prospective cohort

Authors: Sakir Ahmed, Pankti Mehta, Aby Paul, S Anu, Somy Cherian, Veena Shenoy, Kaveri K Nalianda, Sanjana Joseph, Anagha Poulose, Padmanabha Shenoy

Journal: Ann Rheum Dis

PubMed ID: 35135831

Doi: 10.1136/annrheumdis-2021-221922

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