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页码: 120/1028 每页显示数量

Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays

Authors: Beomki Lee, Jae-Hoon Ko, Jiho Park, Hee-Won Moon, Jin Yang Baek, Sunhee Jung, Hee-Young Lim, Kyung-Chang Kim, Kyungmin Huh, Sun Young Cho, Cheol-In Kang, Doo Ryeon Chung, Hee Jae Huh, Chi Ryang Chung, Yae-Jean Kim, Eun-Jeong Joo, Eun-Suk Kang, Kyong Ran Peck

Journal: Front Cell Infect Microbiol

PubMed ID: 35493733

Doi: 10.3389/fcimb.2022.822599

Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi

Authors: Yujie Yuan, Shu Cheng, Guangkai Bian, Pan Yan, Zhengning Ma, Wen Dai, Rong Chen, Shuai Fu, Huiwen Huang, Haoming Chi, Yousheng Cai, Zixin Deng & Tiangang Liu

Journal: Nature Catalysis

Doi: 10.1038/s41929-022-00762-x

Products & Services: Plasmid DNA Preparation

Indirubin-3’-monoxime acts as proteasome inhibitor:Therapeutic application in multiple myeloma

Authors: Zhen Yu , Xiaojing Wei , Lanting Liu , Hao Sun , Teng Fang , Lu Wang , Ying Li , Weiwei Sui , Kefei Wang , Yi He , Yaozhong Zhao , Wenyang Huang , Gang An , Fancui Meng , Changjiang Huang , Tengteng Yu , Kenneth C Anderson , Tao Cheng , Lugui Qiu , Mu Hao

Journal: EBioMedicine

PubMed ID: 35344764

Doi: 10.1016/j.ebiom.2022.103950

Products & Services: Proteins, Expression, Isolation and Analysis

Premetazoan Origin of Neuropeptide Signaling

Authors: Luis Alfonso Yañez-Guerra, Daniel Thiel, Gáspár Jékely

Journal: Mol Biol Evol

PubMed ID: 35277960

Doi: 10.1093/molbev/msac051

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Alternative splicing of an exitron determines the subnuclear localization of the Arabidopsis DNA glycosylase MBD4L under heat stress

Authors: Nicolás Miguel Cecchini , José Roberto Torres , Ignacio Lescano López, Santiago Cobo, Florencia Nota, María Elena Alvarez

Journal: Plant J

PubMed ID: 35061303

Doi: 10.1111/tpj.15675

Products & Services: Molecular Biology Reagents

Specification of CNS macrophage subsets occurs postnatally in defined niches

Authors: Takahiro Masuda, Lukas Amann, Gianni Monaco, Roman Sankowski, Ori Staszewski, Martin Krueger, Francesca Del Gaudio, Liqun He, Neil Paterson, Elisa Nent, Francisco Fernández-Klett, Ayato Yamasaki, Maximilian Frosch, Maximilian Fliegauf, Lance Fredrick Pahutan Bosch, Hatice Ulupinar, Nora Hagemeyer, Dietmar Schreiner, Cayce Dorrier, Makoto Tsuda, Claudia Grothe, Anne Joutel, Richard Daneman, Christer Betsholtz, Urban Lendahl, Klaus-Peter Knobeloch, Tim Lämmermann, Josef Priller, Katrin Kierdorf, Marco Prinz

Journal: Nature

PubMed ID: 35444273

Doi: 10.1038/s41586-022-04596-2

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Real meat and plant-based meat analogues have different in vitro protein digestibility properties

Authors: Yunting Xie, Linlin Cai, Di Zhao, Hui Liu, Xinglian Xu, Guanghong Zhou, Chunbao Li

Journal: Food Chem

PubMed ID: 35413556

Doi: 10.1016/j.foodchem.2022.132917

Products & Services: Proteins, Expression, Isolation and Analysis

Structural insights into the peptide selectivity and activation of human neuromedin U receptors

Authors: Chongzhao You , Yumu Zhang , Peiyu Xu , Sijie Huang , Wanchao Yin, H Eric Xu , Yi Jiang

Journal: Nat Commun

PubMed ID: 35440625

Doi: 10.1038/s41467-022-29683-w

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Characterization of Calcium-Dependent Protein Kinase 2A, a Potential Drug Target Against Cryptosporidiosis

Authors: Fanfan Shu, Yu Li, Wenlun Chu, Xuehua Chen, Ziding Zhang, Yaqiong Guo, Yaoyu Feng, Lihua Xiao, Na Li

Journal: Front Microbiol

PubMed ID: 35558125

Doi: 10.3389/fmicb.2022.883674

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Hypericin nanoparticles for self-illuminated photodynamic cytotoxicity based on bioluminescence resonance energy transfer

Authors: Hao-Han Yu, Qiu-Ping Deng, Qing-Hua Zheng, Yi Wang, Jian Shen, Jia-Hong Zhou

Journal: Int J Pharm

PubMed ID: 35427744

Doi: 10.1016/j.ijpharm.2022.121738

Products & Services: Plasmid DNA Preparation

Artemether inhibits proliferation, invasion and migration of hepatocellular carcinoma cells via targeting of CYP2J2

Authors: Xionglin Zhu, Mei Yang, Zhiling Song, Guangbing Yao, Qifeng Shi

Journal: Oncol Lett

PubMed ID: 35464300

Doi: 10.3892/ol.2022.13300

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Secretes Small RNA to Target Host and Retard Plant Floral Transition During Infection

Authors: Bo-Sen Zhang, Ying-Chao Li, Hui-Shan Guo, Jian-Hua Zhao

Journal: Front Plant Sci

PubMed ID: 35519822

Doi: 10.3389/fpls.2022.847086

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A Novel Multi-Epitope Edible Vaccine Candidate for Newcastle Disease Virus: Approach

Authors: Atena Mozafari, Jafar Amani, Shahla Shahsavandi, Ali Hatef Salmanian

Journal: Iran J Biotechnol

PubMed ID: 36337069

Doi: 10.30498/ijb.2022.298822.3119

Products & Services: Molecular Biology Tools

Family 1 Glycosyltransferase UGT706F8 from Selectively Catalyzes the Synthesis of Silibinin 7--β-d-Glucoside

Authors: Gonzalo N Bidart, Natalia Putkaradze, Folmer Fredslund, Christian Kjeldsen, Ander Garralda Ruiz, Jens Ø Duus, David Teze, Ditte H Welner

Journal: ACS Sustain Chem Eng

PubMed ID: 35493695

Doi: 10.1021/acssuschemeng.1c07593

Products & Services: Bacterial Expression

Novel insight into the transformation of peptides and potential benefits in brown fermented goat milk by mesoporous magnetic dispersive solid phase extraction-based peptidomics

Authors: Wei Jia, An Du, Zibian Fan, Lin Shi

Journal: Food Chem

PubMed ID: 35504074

Doi: 10.1016/j.foodchem.2022.133110

Products & Services: Proteins, Expression, Isolation and Analysis

Development of Antifungal Peptides against Cryptococcus neoformans; Leveraging Knowledge about the Mutant Susceptibility for Lead Compound Development

Authors: Robert J Tancer, Yina Wang, Siddhi Pawar, Chaoyang Xue, Gregory R Wiedman

Journal: Microbiol Spectr

PubMed ID: 35377230

Doi: 10.1128/spectrum.00439-22

Products & Services: Monoclonal Antibody Services

The C-Terminal Transmembrane Domain of Cowpea Mild Mottle Virus TGBp2 Is Critical for Plasmodesmata Localization and for Its Interaction With TGBp1 and TGBp3

Authors: Chong Jiang, Shiqi Shan, Yue Huang, Chenyang Mao, Hehong Zhang, Yanjun Li, Jianping Chen, Zhongyan Wei, Zongtao Sun

Journal: Front Microbiol

PubMed ID: 35495691

Doi: 10.3389/fmicb.2022.860695

Products & Services: Proteins, Expression, Isolation and Analysis

The Copper Resistome of Group B Streptococcus Reveals Insight into the Genetic Basis of Cellular Survival during Metal Ion Stress

Authors: Kelvin G K Goh, Matthew J Sullivan, Glen C Ulett

Journal: J Bacteriol

PubMed ID: 35404113

Doi: 10.1128/jb.00068-22

Products & Services: Mutant Libraries

N-terminal signal peptides facilitate the engineering of PVC complex as a potent protein delivery system

Authors: Feng Jiang, Jiawei Shen, Jiaxuan Cheng, Xia Wang, Jianguo Yang, Ningning Li, Ning Gao, Qi Jin

Journal: Sci Adv

PubMed ID: 35486720

Doi: 10.1126/sciadv.abm2343

Products & Services: Custom DNA/RNA Oligos

MIMAS: microfluidic platform in tandem with MALDI mass spectrometry for protein quantification from small cell ensembles

Authors: Jorvani Cruz Villarreal, Rory Kruithoff, Ana Egatz-Gomez, Paul D Coleman, Robert Ros, Todd R Sandrin, Alexandra Ros

Journal: Anal Bioanal Chem

PubMed ID: 35385983

Doi: 10.1007/s00216-022-04038-y

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Multi-Omics Analysis Reveals That Synergistically Regulates SGAs and Fruit Development

Authors: Hao Guo, Mengdi Mao, Yuan Deng, Lisong Sun, Ridong Chen, Peng Cao, Jun Lai, Yueran Zhang, Chao Wang, Chun Li, Yiran Li, Qunhang Bai, Tingting Tan, Jun Yang, Shouchuang Wang

Journal: Front Plant Sci

PubMed ID: 35463452

Doi: 10.3389/fpls.2022.860577

Products & Services: Protein Tools

The structure of Phocaeicola vulgatus sialic acid acetylesterase

Authors: Hannah Scott, Gideon J Davies, Zachary Armstrong

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 35503212

Doi: 10.1107/S2059798322003357

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Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy

Authors: Chao Wang, Li Fan, Rabia R Khawaja, Bangyan Liu, Lihong Zhan, Lay Kodama, Marcus Chin, Yaqiao Li, David Le, Yungui Zhou, Carlo Condello, Lea T Grinberg, William W Seeley, Bruce L Miller, Sue-Ann Mok, Jason E Gestwicki, Ana Maria Cuervo, Wenjie Luo, Li Gan

Journal: Nat Commun

PubMed ID: 35413950

Doi: 10.1038/s41467-022-29552-6

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Mechanism of RNA polymerase I selection by transcription factor UAF

Authors: Florence Baudin, Brice Murciano, Herman K H Fung, Simon A Fromm, Simone Mattei, Julia Mahamid, Christoph W Müller

Journal: Sci Adv

PubMed ID: 35442737

Doi: 10.1126/sciadv.abn5725

Products & Services: PCR Cloning and Subcloning

A Novel Homozygous Variant Leading to Type-1 Familial Glucocorticoid Deficiency

Authors: Idris Mohammed, Basma Haris, Khalid Hussain

Journal: J Endocr Soc

PubMed ID: 35506146

Doi: 10.1210/jendso/bvac058

Products & Services: Plasmid DNA Preparation

Expanding the Editing Window of Cytidine Base Editors With the Rad51 DNA-Binding Domain in Rice

Authors: Chunjie Wei, Hao Liu, Wenwen Wang, Pengyu Luo, Qiuling Chen, Rou Li, Chong Wang, José Ramón Botella, Hui Zhang

Journal: Front Plant Sci

PubMed ID: 35548314

Doi: 10.3389/fpls.2022.865848

Products & Services: Mammalian Expression

Insights into the inhibition of type I-F CRISPR-Cas system by a multifunctional anti-CRISPR protein AcrIF24

Authors: Lingguang Yang, Laixing Zhang, Peipei Yin, Hao Ding, Yu Xiao, Jianwei Zeng, Wenhe Wang, Huan Zhou, Qisheng Wang, Yi Zhang, Zeliang Chen, Maojun Yang, Yue Feng

Journal: Nat Commun

PubMed ID: 35411005

Doi: 10.1038/s41467-022-29581-1

Products & Services: Mutant Libraries

Cellular Immune Response in Patients Immunized with Three Vaccine Doses of Different Vaccination Schemes Authorized by the Chilean Ministry of Health in January 2022

Authors: Paz Beatriz Tabilo Valenzuela, Gabriela Flores Balter, Gustavo Saint-Pierre Contreras, Daniel Conei Valencia, Catalina Moreno Calderón, Constanza Bohle Venegas, Marcia Guajardo Rivera, Francisco Silva Ojeda, Maria Jesus Vial Covarrubias

Journal: Life (Basel)

PubMed ID: 35455024

Doi: 10.3390/life12040534

Products & Services: Proteins, Expression, Isolation and Analysis

A Novel Immunochromatographic Strip Based on Latex Microspheres for the Rapid Detection of North American-Type Porcine Reproductive and Respiratory Syndrome Virus

Authors: Wansheng Li, Minhua Li, Hongliang Zhang, Chao Li, Hu Xu, Bangjun Gong, Jun Fu, Zhenyang Guo, Jinmei Peng, Guohui Zhou, Zhijun Tian, Qian Wang

Journal: Front Microbiol

PubMed ID: 35572691

Doi: 10.3389/fmicb.2022.882112

Products & Services: Proteins, Expression, Isolation and Analysis

SNX27-Retromer directly binds ESCPE-1 to transfer cargo proteins during endosomal recycling

Authors: Boris Simonetti, Qian Guo, Manuel Giménez-Andrés, Kai-En Chen, Edmund R R Moody, Ashley J Evans, Mintu Chandra, Chris M Danson, Tom A Williams, Brett M Collins, Peter J Cullen

Journal: PLoS Biol

PubMed ID: 35417450

Doi: 10.1371/journal.pbio.3001601

Products & Services: Proteins, Expression, Isolation and Analysis

Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22

Authors: Zehua Sun, Wei Li, John W Mellors, Rimas Orentas, Dimiter S Dimitrov

Journal: Front Immunol

PubMed ID: 35464476

Doi: 10.3389/fimmu.2022.869825

Products & Services: Proteins, Expression, Isolation and Analysis

Suppression of lysosomal-associated protein transmembrane 5 ameliorates cardiac function and inflammatory response by inhibiting the nuclear factor-kappa B (NF-κB) pathway after myocardial infarction in mice

Authors: Zhanchun Song, Xiaozeng Wang, Lianqi He, Liang Chen, Zhichao Ren, Siyu Song

Journal: Exp Anim

PubMed ID: 35491099

Doi: 10.1538/expanim.22-0008

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Reverse Electron Transfer by Respiratory Complex I Catalyzed in a Modular Proteoliposome System

Authors: John J Wright, Olivier Biner, Injae Chung, Nils Burger, Hannah R Bridges, Judy Hirst

Journal: J Am Chem Soc

PubMed ID: 35380814

Doi: 10.1021/jacs.2c00274

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-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone

Authors: Océane Tournière, James M Gahan, Henriette Busengdal, Natascha Bartsch, Fabian Rentzsch

Journal: Sci Adv

PubMed ID: 35442742

Doi: 10.1126/sciadv.abi7109

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Characterization of BLUF-photoreceptors present in Acinetobacter nosocomialis

Authors: Inés Abatedaga, Bárbara Perez Mora, Marisel Tuttobene, Gabriela Müller, Daiana Biancotti, Claudio D Borsarelli, Lorena Valle, Maria A Mussi

Journal: PLoS ONE

PubMed ID: 35442978

Doi: 10.1371/journal.pone.0254291

Products & Services: PCR Cloning and Subcloning

Design of Potent and Proteolytically Stable Biaryl-Stapled GLP-1R/GIPR Peptide Dual Agonists

Authors: Yifang Yang, Candy Lee, Reddy Rajasekhar Reddy, David J Huang, Weixia Zhong, Vân T B Nguyen-Tran, Weijun Shen, Qing Lin

Journal: ACS Chem Biol

PubMed ID: 35417146

Doi: 10.1021/acschembio.2c00175

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Dynamics of Neutralizing Antibody and T-Cell Responses to SARS-CoV-2 and Variants of Concern after Primary Immunization with CoronaVac and Booster with BNT162b2 or ChAdOx1 in Health Care Workers

Authors: Watsamon Jantarabenjakul, Pimpayao Sodsai, Napaporn Chantasrisawad, Anusara Jitsatja, Sasiprapa Ninwattana, Nattakarn Thippamom, Vichaya Ruenjaiman, Chee Wah Tan, Rakchanok Pradit, Jiratchaya Sophonphan, Supaporn Wacharapluesadee, Lin-Fa Wang, Thanyawee Puthanakit, Nattiya Hirankarn, Opass Putcharoen

Journal: Vaccines (Basel)

PubMed ID: 35632395

Doi: 10.3390/vaccines10050639

Products & Services: Recombinant Proteins

Type XX Collagen Is Elevated in Circulation of Patients with Solid Tumors

Authors: Jeppe Thorlacius-Ussing, Christina Jensen, Emilie A Madsen, Neel I Nissen, Tina Manon-Jensen, Inna M Chen, Julia S Johansen, Hadi M H Diab, Lars N Jørgensen, Morten A Karsdal, Nicholas Willumsen

Journal: Int J Mol Sci

PubMed ID: 35456962

Doi: 10.3390/ijms23084144

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Inhibitor of DNA binding 2 (ID2) regulates the expression of developmental genes and tumorigenesis in ewing sarcoma

Authors: Stacia L Koppenhafer, Kelli L Goss, Ellen Voigt, Emma Croushore, William W Terry, Jason Ostergaard, Peter M Gordon, David J Gordon

Journal: Oncogene

PubMed ID: 35422476

Doi: 10.1038/s41388-022-02310-0

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Immunization With Recombinant Y75B8A8 Partially Protects Local Crossbred Female Goats From Infection

Authors: Xiaowei Tian, Mingmin Lu, Yongqian Bu, Yang Zhang, Kalibixiati Aimulajiang, Meng Liang, Charles Li, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li

Journal: Front Vet Sci

PubMed ID: 35445096

Doi: 10.3389/fvets.2022.765700

Products & Services: Proteins, Expression, Isolation and Analysis

Development of an Indirect ELISA Kit for Rapid Detection of Varicella-Zoster Virus Antibody by Glycoprotein E

Authors: Yan Niu, Aiping Wang, Jingming Zhou, Hongliang Liu, Yumei Chen, Peiyang Ding, Yanhua Qi, Chao Liang, Xifang Zhu, Gaiping Zhang

Journal: Front Microbiol

PubMed ID: 35572642

Doi: 10.3389/fmicb.2022.897752

Products & Services: Mammalian Expression

The miR-532-E2F1 feedback loop contributes to gastric cancer progression

Authors: Shanting Gao, Xiaomin Bu, Yongyue Gao, Zengtao Bao, Wenchao Shi, Lipeng Luan, Huiyu Chen, Baoming Zhang, Qingshui Tian, Wenxian Guan, Liuqing Yang

Journal: Cell Death Dis

PubMed ID: 35440106

Doi: 10.1038/s41419-022-04832-7

Products & Services: Plasmid DNA Preparation

is a 3D matrix-specific mediator of mechanosensitive stem cell lineage commitment

Authors: Jieung Baek, Paola A Lopez, Sangmin Lee, Taek-Soo Kim, Sanjay Kumar, David V Schaffer

Journal: Sci Adv

PubMed ID: 35427160

Doi: 10.1126/sciadv.abm4646

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A single point mutation in the Plasmodium falciparum 3'-5' exonuclease does not alter piperaquine susceptibility

Authors: Nonlawat Boonyalai, Kirakarn Kirativanich, Chatchadaporn Thamnurak, Chantida Praditpol, Brian A Vesely, Mariusz Wojnarski, John S Griesenbeck, Norman C Waters

Journal: Malar J

PubMed ID: 35459163

Doi: 10.1186/s12936-022-04148-z

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Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery

Authors: Tian Zhou, Xinyi Zhu, Zhizhong Ye, Yong-Fei Wang, Chao Yao, Ning Xu, Mi Zhou, Jianyang Ma, Yuting Qin, Yiwei Shen, Yuanjia Tang, Zhihua Yin, Hong Xu, Yutong Zhang, Xiaoli Zang, Huihua Ding, Wanling Yang, Ya Guo, John B Harley, Bahram Namjou, Kenneth M Kaufman, Leah C Kottyan, Matthew T Weirauch, Guojun Hou, Nan Shen

Journal: Nat Commun

PubMed ID: 35388006

Doi: 10.1038/s41467-022-29514-y

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Distinct Stress-Dependent Signatures of Cellular and Extracellular tRNA-Derived Small RNAs

Authors: Guoping Li, Aidan C Manning, Alex Bagi, Xinyu Yang, Priyanka Gokulnath, Michail Spanos, Jonathan Howard, Patricia P Chan, Thadryan Sweeney, Robert Kitchen, Haobo Li, Brice D Laurent, Sary F Aranki, Maria I Kontaridis, Louise C Laurent, Kendall Van Keuren-Jensen, Jochen Muehlschlegel, Todd M Lowe, Saumya Das

Journal: Adv Sci (Weinh)

PubMed ID: 35373532

Doi: 10.1002/advs.202200829

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Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis

Authors: Yiqi Yang , Yixuan Lin , Minqi Wang , Kai Yuan , Qishan Wang , Pei Mu , Jingke Du , Zhifeng Yu , Shengbing Yang ， Kai Huang , Yugang Wang , Hanjun Li , Tingting Tang

Journal: Bone Res

PubMed ID: 35260560

Doi: doi.org/10.1038/s41413-022-00198-w

Products & Services: Proteins, Expression, Isolation and Analysis

DNA immunotherapy targeting BARF1 induces potent anti-tumor responses against Epstein-Barr-virus-associated carcinomas

Authors: Xizhou Zhu, Alfredo Perales-Puchalt, Krzysztof Wojtak, Ziyang Xu, Kun Yun, Pratik S Bhojnagarwala , Devivasha Bordoloi , Daniel H Park, Kevin Liaw, Mamadou A Bah, Paul M Lieberman , Ebony N Gary , Ami Patel , David B Weiner

Journal: Mol Ther Oncolytics

PubMed ID: 35071745

Doi: 10.1016/j.omto.2021.12.017

Products & Services: Plasmid DNA Preparation Peptide Synthesis

RNF115 Inhibits the Post-ER Trafficking ofTLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination ofRAB1A and RAB13

Authors: Zhi-Dong Zhang , Hong-Xu Li , Hu Gan , Zhen Tang , Yu-Yao Guo , Shu-Qi Yao , Tianzi Liuyu , Bo Zhong , Dandan Lin

Journal: Adv Sci (Weinh)

PubMed ID: 35343654

Doi: doi.org/10.1002/advs.202105391

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SARS-CoV-2 variant B.1.1.7 caused HLA-A2 CD8 T cell epitope mutations for impaired cellular immune response.

Authors: Chanchan Xiao, Lipeng Mao , Zhigang Wang , Lijuan Gao , Guodong Zhu , Jun Su , Xiongfei Chen , Jun Yuan , Yutian Hu, Zhinan Yin, Jun Xie , Weiqing Ji , Haitao Niu , Feng Gao, Oscar Junhong Luo , Lianbo Xiao , Pengcheng Wang , Guobing Chen

Journal: iScience

PubMed ID: 35194575

Doi: 10.1016/j.isci.2022.103934

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