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Production of norovirus-, rotavirus-, and enterovirus-like particles in insect cells is simplified by plasmid-based expression
Authors: Vili Lampinen, Stina Gröhn, Nina Lehmler, Minne Jartti, Vesa P Hytönen, Maren Schubert, Minna M Hankaniemi
Journal: Sci Rep
PubMed ID: 38937523
Doi: 10.1038/s41598-024-65316-6
Products & Services: Molecular Biology Reagents   
Cost-Efficient Expression of Human Cardiac Myosin Heavy Chain in C2C12 Cells with a Non-Viral Transfection Reagent
Authors: Albin E Berg, Lok Priya Velayuthan, Alf Månsson, Marko Ušaj
Journal: Int J Mol Sci
PubMed ID: 38928453
Doi: 10.3390/ijms25126747
Products & Services: Molecular Biology Reagents   
CircVIRMA enhances cell malignant behavior by governing the miR-452-5p/CREBRF pathway in cervical cancer
Authors: Chengluo Hao, Jianjun Han, Kechao Xiang, Yun Wang, Xiangrui Chen, Chen Yang, Ailin Liang, Li Jia
Journal: Naunyn Schmiedebergs Arch Pharmacol
PubMed ID: 38850300
Doi: 10.1007/s00210-024-03159-8
Products & Services: Molecular Biology Reagents   
Circ_002033 Regulates Proliferation, Apoptosis, and Oxidative Damage of Bovine Mammary Epithelial Cells via the miR-199a-5p-MAP3K11 Axis in Heat Stress
Authors: Hanfang Zeng, Shujie Li, Haomiao Chang, Yunfei Zhai, Haihui Wang, Hantong Weng, Zhaoyu Han
Journal: J Agric Food Chem
PubMed ID: 38869955
Doi: 10.1021/acs.jafc.3c09835
Immune responses and reinfection of SARS-CoV-2 Omicron variant in patients with lung cancer
Authors: Chen Chen, Xiaoyun Zhou, Xiaoxing Gao, Ruili Pan, Qi He, Xiaobei Guo, Siyuan Yu, Na Wang, Qian Zhao, Mengzhao Wang, Yan Xu, Xiaohong Han
Journal: Int J Cancer
PubMed ID: 38837354
Doi: 10.1002/ijc.35038
Products & Services: Catalog Peptides   
Structure of the E. coli nucleoid-associated protein YejK reveals a novel DNA binding clamp
Authors: Maria A Schumacher, Rajiv R Singh, Raul Salinas
Journal: Nucleic Acids Res
PubMed ID: 38832628
Doi: 10.1093/nar/gkae459
NbPTR1 confers resistance against Pseudomonas syringae pv actinidiae in kiwifruit
Authors: Shin-Mei Yeh, Minsoo Yoon, Sidney Scott, Abhishek Chatterjee, Lauren M Hemara, Ronan K Y Chen, Tianchi Wang, Kerry Templeton, Erik H A Rikkerink, Jay Jayaraman, Cyril Brendolise
Journal: Plant Cell Environ
PubMed ID: 38899426
Doi: 10.1111/pce.15002
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Double promoter and tandem gene strategy for efficiently expressing recombinant FGF21
Authors: Longying Liu, Nuoyi Ning, Simeng Xu, Dongqing Chen, Luping Zhou, Zhimou Guo, Xinmiao Liang, Xianlong Ye
Journal: Microb Cell Fact
PubMed ID: 38867280
Doi: 10.1186/s12934-024-02447-5
Products & Services: Gene Synthesis   
Development of a Ferritin Protein Nanoparticle Vaccine with PRRSV GP5 Protein
Authors: Xinjian Chang, Jun Ma, Yanrong Zhou, Shaobo Xiao, Xun Xiao, Liurong Fang
Journal: Viruses
PubMed ID: 38932282
Doi: 10.3390/v16060991
Products & Services: Molecular Biology Reagents   
Discovery, characterization, and comparative analysis of new UGT72 and UGT84 family glycosyltransferases
Authors: Tuo Li, Annika J E Borg, Leo Krammer, Hansjörg Weber, Rolf Breinbauer, Bernd Nidetzky
Journal: Commun Chem
PubMed ID: 38942997
Doi: 10.1038/s42004-024-01231-1
Products & Services: Molecular Biology Reagents   
DNA mismatch and damage patterns revealed by single-molecule sequencing
Authors: Mei Hong Liu, Benjamin M Costa, Emilia C Bianchini, Una Choi, Rachel C Bandler, Emilie Lassen, Marta Grońska-Pęski, Adam Schwing, Zachary R Murphy, Daniel Rosenkjær, Shany Picciotto, Vanessa Bianchi, Lucie Stengs, Melissa Edwards, Nuno Miguel Nunes, Caitlin A Loh, Tina K Truong, Randall E Brand, Tomi Pastinen, J Richard Wagner, Anne-Bine Skytte, Uri Tabori, Jonathan E Shoag, Gilad D Evrony
Journal: Nature
PubMed ID: 38867045
Doi: 10.1038/s41586-024-07532-8
Products & Services: Molecular Biology Reagents   
IgE-Mediated Sensitization to Blo t 21 and Blo t 5 Is Associated With Asthma in the Tropics: A Case-Control Study
Authors: J Zakzuk, K Donado, E Mondol, V Marrugo, R Regino, J F López, K Hernandez, D Mercado, R Dennis, L Puerta, L Caraballo
Journal: J Investig Allergol Clin Immunol
PubMed ID: 38888580
Doi: 10.18176/jiaci.0892
Products & Services: Molecular Biology Reagents   
C-terminal Poly-histidine Tags Alter Escherichia coli Polyphosphate Kinase Activity and Susceptibility to Inhibition
Authors: Marvin Q Bowlin, Avery D Lieber, Abagail R Long, Michael J Gray
Journal: J Mol Biol
PubMed ID: 38866092
Doi: 10.1016/j.jmb.2024.168651
Products & Services: Molecular Biology Reagents   
A soybean cyst nematode suppresses microbial plant symbionts using a lipochitooligosaccharide-hydrolysing enzyme
Authors: Wei Chen, Di Wang, Shaoyong Ke, Yangrong Cao, Wensheng Xiang, Xiaoli Guo, Qing Yang
Journal: Nat Microbiol
PubMed ID: 38886584
Doi: 10.1038/s41564-024-01727-5
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Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2
Authors: J Wouter Beugelink, Els Sweep, Bert J C Janssen, Joost Snijder, Matti F Pronker
Journal: J Mol Biol
PubMed ID: 38852931
Doi: 10.1016/j.jmb.2024.168649
Products & Services: Catalog Peptides   
Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice
Authors: Szu-Hsien Sam Wu, Somi Kim, Heetak Lee, Ji-Hyun Lee, So-Yeon Park, Réka Bakonyi, Isaree Teriyapirom, Natalia Hallay, Sandra Pilat-Carotta, Hans-Christian Theussl, Jihoon Kim, Joo-Hyeon Lee, Benjamin D Simons, Jong Kyoung Kim, Gabriele Colozza, Bon-Kyoung Koo
Journal: Nat Commun
PubMed ID: 38862535
Doi: 10.1038/s41467-024-49382-y
Products & Services: Molecular Biology Reagents   
New wheat straw fermentation feed: recombinant efficient degradation of lignocellulose and increase feed protein
Authors: Xihua Chen, Xiaoyu Liang, Na Shi, Lu He, Yi Ma, Daochen Zhu, Zhong Ni, Huayou Chen
Journal: Prep Biochem Biotechnol
PubMed ID: 38824495
Doi: 10.1080/10826068.2024.2353637
Products & Services: Gene Synthesis   
TnpB homologues exapted from transposons are RNA-guided transcription factors
Authors: Tanner Wiegand, Florian T Hoffmann, Matt W G Walker, Stephen Tang, Egill Richard, Hoang C Le, Chance Meers, Samuel H Sternberg
Journal: Nature
PubMed ID: 38926585
Doi: 10.1038/s41586-024-07598-4
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system
Authors: Olawale G Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M Lange, Cristian Polo Rivera, Tom D Deegan, Yinchen Chen, Melanie Wightman, Rachel Toth, Karim P M Labib, Sebastian Mathea, Neil Ranson, Rubén Fernández-Busnadiego, Miratul M K Muqit
Journal: SCIENCE ADVANCES
PubMed ID: 38848361
Doi: 10.1126/sciadv.adn7191
Understanding the Phase Behavior of a Multistimuli-Responsive Elastin-like Polymer: Insights from Dynamic Light Scattering Analysis
Authors: Peter C Swanson, Galen P Arnold, Carolyn E Curley, Savannah C Wakita, Jeffery D V Waters, Eva Rose M Balog
Journal: J Phys Chem B
PubMed ID: 38830627
Doi: 10.1021/acs.jpcb.4c00070
Products & Services: Molecular Biology Reagents   
Cholesterol neutralized vemurafenib treatment by promoting melanoma stem‑like cells via its metabolite 27‑hydroxycholesterol
Authors: Xiaohong Wang, Feiliang Zhong, Tingting Chen, Hongbo Wang, Weifang Wang, Hongkai Jin, Chouyang Li, Xuan Guo, Ying Liu, Yu Zhang, Bo Li
Journal: Cell Mol Life Sci
PubMed ID: 38775844
Doi: 10.1007/s00018-024-05267-3
Engineered probiotics with sustained release of interleukin-2 for the treatment of inflammatory bowel disease after oral delivery
Authors: Maoyi Li, Nanhui Liu, Jiafei Zhu, Yumin Wu, Le Niu, Yi Liu, Linfu Chen, Boxiong Bai, Yu Miao, Yang Yang, Qian Chen
Journal: Biomaterials
PubMed ID: 38735180
Doi: doi.org/10.1016/j.biomaterials.2024.122584
Products & Services: Catalog Antibody   
Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry
Authors: Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J Gibbings, Laura Trinkle-Mulcahy, John W Copeland
Journal: Int J Mol Sci
PubMed ID: 38891874
Doi: 10.3390/ijms25115686
Blue light-mediated gene expression as a promising strategy to reduce antibiotic resistance in Escherichia coli
Authors: Qingwei Jiang, Feng Geng, Juan Shen, Ping Zhu, Zhaoxin Lu, Fengxia Lu, Libang Zhou
Journal: Biotechnol J
PubMed ID: 38719589
Doi: 10.1002/biot.202400023
Effect of Free Cysteine Residues to Serine Mutation on Cellodextrin Phosphorylase
Authors: Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi
Journal: J Appl Glycosci (1999)
PubMed ID: 38863949
Doi: 10.5458/jag.jag.JAG-2023_0011
Products & Services: Molecular Biology Reagents   
Micro-and nano-plastics induce kidney damage and suppression of innate immune function in zebrafish (Danio rerio) larvae
Authors: Hui Yang, Jian Ju, Yuting Wang, Zhu Zhu, Wenyan Lu, Yingying Zhang
Journal: Sci Total Environ
PubMed ID: 38703841
Doi: 10.1016/j.scitotenv.2024.172952
Products & Services: Catalog Antibody   
Tetrahydroxy stilbene glucoside rejuvenates aging hematopoietic stem cells with predilection for lymphoid differentiation via AMPK and Tet2
Authors: Dan Gao, Wei-Wei Yi, Bo Liu, Cong-En Zhang, Cui-Cui Yang, Li Zeng, Lin Li, Guangbin Luo, Lan Zhang, Zhen-Yu Ju, Jia-Bo Wang
Journal: J Adv Res
PubMed ID: 38704089
Doi: 10.1016/j.jare.2024.04.027
CRTAC1 identified as a promising diagnosis and prognostic biomarker in lung adenocarcinoma
Authors: Lin Tan, Han Zhang, Yun Ding, Yangyun Huang, Daqiang Sun
Journal: Sci Rep
PubMed ID: 38755183
Doi: 10.1038/s41598-024-61804-x
A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy
Authors: Dan A Tudorica, Bishal Basak, Alexia S Puerta Cordova, Grace Khuu, Kevin Rose, Michael Lazarou, Erika L F Holzbaur, James H Hurley
Journal: J Cell Biol
PubMed ID: 38728007
Doi: 10.1083/jcb.202309015
Products & Services: Molecular Biology Reagents   
Antitumor activity of Z15-0-2, a bispecific nanobody targeting PD-1 and CTLA-4
Authors: Jianyao Zeng, Yuan Fang, Zixuan Zhang, Zhenzhen Lv, Xiaodie Wang, Qian Huang, Zhidan Tian, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Jing Yu, Tao Liu, Qijun Qian
Journal: Oncogene
PubMed ID: 38806619
Doi: 10.1038/s41388-024-03066-5
Post-transcriptional regulation of the T-box gene midline via the 3'UTR in Drosophila is complex and cell and tissue-dependent
Authors: Kalpana Makhijani, Jordan Mar, Ivana Gaziova, Krishna Moorthi Bhat
Journal: Genetics
PubMed ID: 38805187
Doi: 10.1093/genetics/iyae087
Products & Services: Molecular Biology Reagents   
Identification and characterization of calcium binding protein, spermatid-associated 1 (CABS1)# in selected human tissues and fluids
Authors: Eduardo Reyes-Serratos, Joy Ramielle L Santos, Lakshmi Puttagunta, Stephen J Lewis, Mechiko Watanabe, Aron Gonshor, Robert Buck, A Dean Befus, Marcelo Marcet-Palacios
Journal: PLoS ONE
PubMed ID: 38753592
Doi: 10.1371/journal.pone.0301855
EDA2R knockdown alleviates myocardial ischemia/reperfusion injury through inhibiting the activation of the NF-κB signaling pathway
Authors: Zhi-Hui Guan, Di Yang, Yi Wang, Jia-Bin Ma, Guo-Nian Wang
Journal: Exp Anim
PubMed ID: 38797667
Doi: 10.1538/expanim.24-0020
Products & Services: Molecular Biology Reagents   
Filtered Saliva for Rapid and Accurate Analyte Detection for POC Diagnostics
Authors: Nadia Farsaeivahid, Christian Grenier, Ming L Wang
Journal: Diagnostics (Basel)
PubMed ID: 38893615
Doi: 10.3390/diagnostics14111088
BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation
Authors: Swati Garg, Wei Ni, Basudev Chowdhury, Ellen L Weisberg, Martin Sattler, James D Griffin
Journal: Cell Death Differ
PubMed ID: 38816579
Doi: 10.1038/s41418-024-01306-5
Products & Services: Molecular Biology Reagents   
L-serine deficiency: on the properties of the Asn133Ser variant of human phosphoserine phosphatase
Authors: Loredano Pollegioni, Barbara Campanini, Jean-Marc Good, Zoraide Motta, Giulia Murtas, Valeria Buoli Comani, Despina-Christina Pavlidou, Noëlle Mercier, Laureane Mittaz-Crettol, Silvia Sacchi, Francesco Marchesani
Journal: Sci Rep
PubMed ID: 38816452
Doi: 10.1038/s41598-024-63164-y
Insights into PCSK9-LDLR Regulation and Trafficking via the Differential Functions of MHC-I Proteins HFE and HLA-C
Authors: Sepideh Mikaeeli, Ali Ben Djoudi Ouadda, Alexandra Evagelidis, Rachid Essalmani, Oscar Henrique Pereira Ramos, Carole Fruchart-Gaillard, Nabil G Seidah
Journal: Cells
PubMed ID: 38786080
Doi: 10.3390/cells13100857
Products & Services: Mutant Libraries   
Gene network-based and ensemble modeling-based selection of tumor-associated antigens with a predicted low risk of tissue damage for targeted immunotherapy
Authors: Christopher Lischer, Martin Eberhardt, Cindy Flamann, Johannes Berges, Esther Güse, Anja Wessely, Adrian Weich, Jimmy Retzlaff, Jan Dörrie, Niels Schaft, Manuel Wiesinger, Johannes März, Beatrice Schuler-Thurner, Harald Knorr, Shailendra Gupta, Krishna Pal Singh, Gerold Schuler, Markus Vincent Heppt, Elias Andreas Thomas Koch, Nadine D van Kleef, Julian J Freen-van Heeren, Annelies W Turksma, Olaf Wolkenhauer, Bettina Hohberger, Carola Berking, Heiko Bruns, Julio Vera
Journal: J Immunother Cancer
PubMed ID: 38724462
Doi: 10.1136/jitc-2023-008104
Products & Services: Gene Synthesis   
CircZFR promotes colorectal cancer progression via stabilizing BCLAF1 and regulating the miR-3127-5p/RTKN2 axis
Authors: Jiaxin Chen, Huijuan Wang, Jianbin Xu, Engeng Chen, Qing Meng, Jiawei Wang, Haoyi Xiang, Wei Zhou, Ge Shan, Zhenyu Ju, Zhangfa Song
Journal: Sci China Life Sci
PubMed ID: 38805063
Doi: 10.1007/s11427-023-2514-y
Construction of a grpE-based plasmid addiction system in Escherichia coli and its application in phloroglucinol biosynthesis
Authors: Ji-Ming Wang, Yu-Jin Cao, Xiao Men, Hai-Bo Zhang
Journal: J Appl Microbiol
PubMed ID: 38724452
Doi: 10.1093/jambio/lxae116
Detection of calcitonin gene-related peptide based on increased antigen-driven interaction with antibody variable regions
Authors: Yueqing Cheng, Yujie Gao, Shengshuo Zhang, Yujie Zou, Guangwei Zhao, Liyuan Zheng, Binghui Hou, Mei Li, Jinhua Dong
Journal: Front Bioeng Biotechnol
PubMed ID: 38882635
Doi: 10.3389/fbioe.2024.1395330
Products & Services: Molecular Biology Reagents   
Glycan Profile and Sequence Variants of Certified Ricin Reference Material and Other Ricin Samples Yield Unique Molecular Signature Features
Authors: Roland Josuran, Andreas Wenger, Christian Müller, Bettina Kampa, Sylvia Worbs, Brigitte G Dorner, Sabina Gerber
Journal: Toxins (Basel)
PubMed ID: 38922138
Doi: 10.3390/toxins16060243
TOP CAR with TMIGD2 as a safe and effective costimulatory domain in CAR cells treating human solid tumors
Authors: Christopher D Nishimura, Devin Corrigan, Xiang Yu Zheng, Phillip M Galbo, Shan Wang, Yao Liu, Yao Wei, Linna Suo, Wei Cui, Nadia Mercado, Deyou Zheng, Cheng Cheng Zhang, Xingxing Zang
Journal: Sci Adv
PubMed ID: 38718110
Doi: 10.1126/sciadv.adk1857
HIV BG505 SOSIP664 trimer with 3M-052-AF/alum induces human autologous tier-2 neutralizing antibodies
Authors: William O Hahn, K Rachael Parks, Mingchao Shen, Gabriel Ozorowski, Holly Janes, Lamar Ballweber-Fleming, Amanda S Woodward Davis, Chris Duplessis, Mark Tomai, Antu K Dey, Zachary K Sagawa, Stephen C De Rosa, Aaron Seese, Latha Kallur Siddaramaiah, Leonidas Stamatatos, Wen-Hsin Lee, Leigh M Sewall, Dalton Karlinsey, Hannah L Turner, Vanessa Rubin, Sarah Furth, Kellie MacPhee, Michael Duff, Lawrence Corey, Michael C Keefer, Srilatha Edupuganti, Ian Frank, Janine Maenza, Lindsey R Baden, Ollivier Hyrien, Rogier W Sanders, John P Moore, Andrew B Ward, Georgia D Tomaras, David C Montefiori, Nadine Rouphael, M Juliana McElrath
Journal: medrxiv
PubMed ID: 38766048
Doi: 10.1101/2024.05.08.24306957
Products & Services: Monoclonal Antibody Services   
The intrinsic substrate specificity of the human tyrosine kinome
Authors: Tomer M. Yaron-Barir, Brian A. Joughin, Emily M. Huntsman, Alexander Kerelsky, Daniel M. Cizin, Benjamin M. Cohen, Amit Regev, Junho Song, Neil Vasan, Ting-Yu Lin, Jose M. Orozco, Christina Schoenherr, Cari Sagum, Mark T. Bedford, R. Max Wynn, Shih-Chia Tso, David T. Chuang, Lei Li, Shawn S.-C. Li, Pau Creixell, Konstantin Krismer, Mina Takegami, Harin Lee, Bin Zhang, Jingyi Lu, Ian Cossentino, Sean D. Landry, Mohamed Uduman, John Blenis, Olivier Elemento, Margaret C. Frame, Peter V. Hornbeck, Lewis C. Cantley, Benjamin E. Turk, Michael B. Yaffe & Jared L. Johnson
Journal: Nature
PubMed ID: 38720073
Doi: 10.1038/s41586-024-07407-y
Products & Services: Codon Optimization   
Contemporary HIV-1 consensus Env with AI-assisted redesigned hypervariable loops promote antibody binding
Authors: Hongjun Bai, Eric Lewitus, Yifan Li, Paul V. Thomas, Michelle Zemil, Mélanie Merbah, Caroline E. Peterson, Thujitha Thuraisamy, Phyllis A. Rees, Agnes Hajduczki, Vincent Dussupt, Bonnie Slike, Letzibeth Mendez-Rivera, Annika Schmid, Erin Kavusak, Mekhala Rao, Gabriel Smith, Jessica Frey, Alicea Sims, Lindsay Wieczorek, Victoria Polonis, Shelly J. Krebs, Julie A. Ake, Sandhya Vasan, Diane L. Bolton, M. Gordon Joyce, Samantha Townsley & Morgane Rolland
Journal: Nat Commun
PubMed ID: 38724518
Doi: 10.1038/s41467-024-48139-x
Products & Services: Gene Synthesis   
Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin
Authors: Di Qu, Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton, James M. Bean, Inna V. Krieger, James C. Sacchettini, Sabine Ehrt, Courtney C. Aldrich & Dirk Schnappinger
Journal: Nat Commun
PubMed ID: 38755122
Doi: 10.1038/s41467-024-48448-1.
Products & Services: Catalog Antibody   
Enhanced detection of ligand-PPARγ binding based on surface plasmon resonance through complexation with SRC1- or NCOR2-related polypeptide
Authors: Yiting Wang , Mingzhu Luo , Luyang Che , Qixin Wu , Jingzhe Li , Yanyan Ma , Jingyi Wang , Changzhen Liu
Journal: International Journal of Biological Macromolecules
PubMed ID: 38670200
Doi: 10.1016/j.ijbiomac.2024.131865
Products & Services: Gene Synthesis   
A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries
Authors: Angele Bruce , Victor Adebomi , Patrick Czabala , Jonathan Palmer , William M McFadden , Zachary C Lorson , Ryan L Slack , Gaurav Bhardwaj , Stefan G Sarafianos , Monika Raj
Journal: Angew Chem Int Ed Engl
PubMed ID: 38529717
Doi: 10.1002/anie.202320045
Products & Services: PCR Cloning and Subcloning   
Computer-Aided Semi-Rational Design to Enhance the Activity of l-Sorbosone Dehydrogenase from Gluconobacter oxidans WSH-004
Authors: Dong Li, Xinglong Wang, Lin Huo, Weizhu Zeng, Jianghua Li, Jingwen Zhou
Journal: J Agric Food Chem
PubMed ID: 38701424
Doi: 10.1021/acs.jafc.3c08365
Products & Services: Codon Optimization   

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